Acne-removing and repairing extract, preparation method thereof and acne-removing and repairing facial mask containing the same

Abstract

The present invention discloses a plant-derived acne-repairing extract, a preparation method thereof, and an acne-repairing mask containing the same. The plant acne-repairing extract contains extracts of bitter melon, magnolia bark, and wormwood, and by weight, 3 to 10 parts of bitter melon, 5 to 8 parts of magnolia bark, and 0.5 to 5 parts of wormwood. The plant acne-repairing component described in the present invention is formed by compounding extracts of pure natural plant raw materials, and the plant efficacy in the complex also has an antibacterial effect, achieving zero-addition and preservative-free storage, which is gentler and safer. Adding this plant extract complex to the acne-repairing mask can effectively inhibit skin bacterial infection and growth, regulate sebum secretion, significantly eliminate inflammation, promote new muscle growth, repair acne marks, and smooth acne pits.

Description

Technical Field

[0001] The present invention relates to the technical field of daily necessities, and more specifically, to an acne-repairing extract of plant origin, a preparation method thereof and an acne-repairing facial mask containing the extract. Background Art

[0002] Acne, also known as pimples, blackheads, and acne, is caused by abnormal keratinocytes, microbial infection, abnormal hormone secretion, inflammation, and other reasons that damage the structure of the hair follicles and sebaceous glands. Various factors create an environment that is conducive to the growth of Propionibacterium acnes, leading to a vicious cycle of further destruction of the skin microecology. It is a relatively common skin problem at present. With the popularization of electronic products, the abundance of entertainment facilities, and the increasing pace and pressure of work, the huge task of "fighting acne" is not only faced by teenagers in adolescence, but also by middle-aged people who are approaching their thirties. Acne removal products have always been widely in demand.

[0003] Acne products that once abused antibiotics have been eliminated from the market. Due to their drug resistance, irritation and weakened skin resistance, people have turned their attention to natural herbal essences. Acne preparations from natural herbal sources can not only reduce irritation, but also have more significant and lasting acne removal effects. However, single-channel acne removal solutions often cannot meet the needs. Herbal acne essences are difficult to penetrate, and the acne removal process is slow. This has spawned a large number of chemical acne enhancers. Starting from different acne removal mechanisms, they cut off the formation path of acne and destroy the conditions for the formation of acne skin, thereby inhibiting the formation of new acne. For example, exfoliating, regulating sebum secretion, and removing the culprits that clog pores in order to achieve acne suppression effects. Salicylic acid, fruit acid, and azelaic acid are popular. Although these methods can effectively remove hyperactive keratin, permeate hair follicles, correct excessive sebum keratinization, and have obvious acne removal effects, they often have a low pH, high irritation, and are very easy to over-exfoliate, resulting in damage to the skin barrier. After successful acne removal, there is a new problem of sensitive skin.

[0004] Therefore, to this day, there is still a need for gentle and effective acne treatment products. Summary of the invention

[0005] In view of the shortcomings of existing acne removal products, especially the problems of unclear acne removal effect and excessive damage to the skin barrier by chemical acne removal, the present invention provides a mild, effective and fast plant-derived acne repair extract. The extract and the acne repair mask containing the extract can achieve the effects of acne removal, repair and skin strengthening from multiple dimensions such as unblocking pores, regulating sebum secretion, anti-inflammatory and soothing, inhibiting Propionibacterium acnes, repairing acne marks and skin barrier.

[0006] According to one aspect of the present invention, the present invention provides a plant-derived acne-repairing extract, characterized in that it contains extracts of bitter melon, magnolia bark and wormwood, with 3 to 10 parts of bitter melon, 5 to 8 parts of magnolia bark and 0.5 to 5 parts of wormwood in parts by mass.

[0007] In a preferred embodiment, the acne-repairing extract is composed of extracts of bitter melon, magnolia bark and wormwood.

[0008] According to the present invention, the above-mentioned acne-removing and repairing extract is an ethanol extract.

[0009] In the present invention, the above three Chinese herbal compound extracts having both medicinal and edible properties can achieve the effects of removing acne and reducing inflammation, resisting bacteria and preserving, and fading marks and promoting skin regeneration.

[0010] According to another aspect of the present invention, the present invention provides a method for preparing the above-mentioned acne-removing and repairing extract, characterized in that it comprises the following steps:

[0011] (1) Drying bitter melon, Magnolia officinalis, and Artemisia argyi to a moisture content of 12% (±2%) and crushing them;

[0012] (2) Using ethanol aqueous solution with a volume of 5 to 15 times the mass of the dried and crushed bitter melon, Magnolia officinalis, and Artemisia argyi as solvent, extracting for 1 to 5 hours to obtain an alcohol extract.

[0013] (3) Concentrating the alcohol extract to obtain an acne-repairing extract.

[0014] Preferably, bitter melon, Magnolia officinalis and Artemisia argyi are dried, crushed, extracted and concentrated together.

[0015] Preferably, bitter melon, Magnolia officinalis and Artemisia argyi are dried separately, crushed together, extracted and concentrated.

[0016] Preferably, bitter melon, Magnolia officinalis and Artemisia argyi are dried and crushed separately, extracted and concentrated together.

[0017] Preferably, bitter melon, Magnolia officinalis and Artemisia argyi are dried, crushed, extracted and concentrated together.

[0018] Preferably, bitter melon, Magnolia officinalis and Artemisia argyi are dried, crushed, extracted, concentrated and then mixed.

[0019] Preferably, the drying temperature in step (1) is 40-60°C, most preferably 45°C.

[0020] Preferably, the drying time in step (1) is 16-32 hours, most preferably 24 hours.

[0021] Those skilled in the art will appreciate that the pulverization may be performed using various commonly used methods in the art, such as a traditional Chinese medicine pulverizer, etc. Preferably, the pulverization is performed until the pulverization passes through a 20-mesh sieve.

[0022] Preferably, the extraction temperature in step (2) is 45-55°C, most preferably 50°C.

[0023] Preferably, the volume fraction of ethanol in the ethanol aqueous solution in step (2) is at least 60%.

[0024] Preferably, the extraction time in step (2) is 3 hours.

[0025] Preferably, the concentration ratio of the alcohol extract in step (3) (i.e. the volume ratio of the alcohol extract before and after concentration) is 15:1-6:1, most preferably 10:1.

[0026] Preferably, the concentration temperature in step (3) is 37-50°C, most preferably 40°C.

[0027] Those skilled in the art will appreciate that concentration can be performed using various commonly used methods in the art, such as vacuum concentration using a rotary evaporator.

[0028] According to another aspect of the present invention, the present invention provides an acne-repairing extract prepared by the above preparation method.

[0029] According to another aspect of the present invention, the present invention provides an acne-repairing facial mask liquid, characterized in that it contains the above-mentioned acne-repairing extract.

[0030] In a preferred embodiment, the acne-removing and repairing facial mask liquid contains, by mass percentage: 3-15% emollient, 0.1-2% thickener, 0-0.15% neutralizer, 0.5-5% keratin exfoliant, 10-50% of the acne-removing and repairing extract, 0.5-5% oil-control auxiliary acne-removing agent, 0.2-1% anti-inflammatory soothing agent, 0.5-3% repair agent, 0-1% fragrance and / or pigment, and 20-85% deionized water.

[0031] Preferably, the emollient is a polyol, for example, one or more selected from propylene glycol, butylene glycol, glycerol, etc. 1,3-butylene glycol and glycerol are further preferred, and more preferably, the mass ratio of the two is: (1-10):1.

[0032] Preferably, the thickener is selected from one or more of carbomer, acrylic acid (esters), pectin, hyaluronic acid, starch, sodium alginate, xanthan gum, etc. Carbomer U21 is further preferred, which has emulsifying and thickening capabilities, increases the slipperiness and softness of the mask, and enables the system to accommodate a small amount of grease.

[0033] Preferably, the neutralizing agent is selected from one or more of NaOH, KOH, aminomethyl propanol, and triethanolamine. Aminomethyl propanol is further preferred. By adding the neutralizing agent, the pH of the mask liquid is adjusted to 5.5 to 7.0.

[0034] Preferably, the keratin exfoliant may be an acid, for example, one or more selected from VC, VC acetate, azelaic acid, ellagic acid, salicylic acid, fruit acid, glycolic acid, etc. The keratin exfoliant may also be an enzyme, for example, one or more selected from papain, lysozyme, bromelain, etc. The enzymes may reduce the adhesion of desmosomes in keratinocytes, promote the shedding of keratinocytes and skin renewal. Macromolecular papain is further preferred.

[0035] Traditional papain has a small molecular weight and can penetrate deeply into the bottom layer of the skin, thereby decomposing the collagen in the bottom layer of the skin. Large molecular papain is obtained through acrylic polymer encapsulation and immobilization treatment. It can only stay in the epidermis and target the epidermal keratin to achieve zero-irritation peeling and softening, helping the penetration of acne-removing ingredients to play a role, and at the same time can correct the problems of disordered sebum secretion and abnormal cell keratinization in acne-prone skin.

[0036] Preferably, the oil-controlling auxiliary acne-removing agent is niacinamide, which can control oil, brighten and inhibit acne.

[0037] Preferably, the anti-inflammatory and allergy-relief agent is selected from one or more of prebiotics, plant fermentation filtrate, Scutellaria baicalensis extract, Gentiana violet extract, bisabolol, licorice extract, Centella asiatica extract, allantoin, peptides, etc. Dipotassium glycyrrhizinate and allantoin are further preferred, and 0.5% dipotassium glycyrrhizinate and 0.2% allantoin are further preferred.

[0038] Preferably, the repair agent is madecassoside and bilberry seed oil. Further preferably, the mass ratio of the two is: (0.1-1): (0.5-2). The repair agent can help soothe allergies, shrink fibroblasts, promote skin wound healing, fill acne pits, smooth skin texture, strengthen skin barrier, and establish a benign skin keratinization cycle.

[0039] According to another aspect of the present invention, the present invention provides a facial mask patch, which comprises a facial mask base fabric and the facial mask liquid of the present invention. Preferably, the amount of the facial mask liquid in the facial mask patch is 20-30g.

[0040] Those skilled in the art will appreciate that various facial mask base fabrics in the art can be used in the present invention.

[0041] The beneficial effects of the present invention are as follows:

[0042] The present invention provides a plant-derived acne-repairing extract and its application in an acne-repairing mask. The plant-derived acne-repairing extract is derived from all-natural herbal plants, has low irritation, and has multiple functions of acne removal, antiseptic and anti-inflammatory, can simplify the formula, and reduce the proportion of chemical components. The acne-repairing mask contains 5-dimensional acne-repairing technology: First, by matching with macromolecular papain, it is mild and zero-irritating, and it exfoliates the cutin in a targeted manner to dredge blocked hair follicles; second, the plant-derived acne-repairing extract has both acne removal and antiseptic, and the effects of lightening marks and regenerating skin; third, niacinamide assists in oil control and anti-inflammatory, brightens scarred acne skin, corrects and strengthens the normal secretion function of sebum; fourth, dipotassium glycyrrhizinate is matched with allantoin for anti-inflammatory and soothing, protecting the skin that sees the light again; fifth, madecassoside is matched with European bilberry seed oil to reshape the skin barrier, strengthen the immunity of acne skin, and fill pits and lighten marks. The five-dimensional acne-removing scheme follows the principle of monarch, minister, assistant and envoy, synergistically enhances synergy, can quickly remove acne and lighten marks, and is mild, soothing and non-irritating, effectively solving the shortcomings of existing products. BRIEF DESCRIPTION OF THE DRAWINGS

[0043] Figure 1 Changes in the average scores of volunteers' skin health visa indicators

[0044] Figure 2 Comparison of the acne condition of volunteer 1 before and after using the anti-acne mask of Example 7

[0045] Figure 3 Comparison of acne scars on the face of volunteer 2 before and after using the anti-acne mask of Example 10 DETAILED DESCRIPTION

[0046] The present invention will be further described below in conjunction with specific embodiments. It should be understood that these embodiments are only used to illustrate the present invention and are not intended to limit the scope of the present invention. In addition, it should be understood that after reading the content recorded in the present invention, those skilled in the art can make various changes or modifications to the present invention, and these equivalent forms fall within the scope limited by the present invention equally.

[0047] Example 1

[0048] The plant-derived acne-repairing extract of the present invention is prepared according to the following steps:

[0049] S1, placing 600 g of bitter melon, 800 g of Magnolia officinalis, and 200 g of Artemisia argyi in an oven at 45° C. for 24 hours, and crushing them together with a traditional Chinese medicine grinder to obtain a mixed powder.

[0050] S2, add 60% ethanol aqueous solution with a volume fraction of 10 times the mass of the mixed powder obtained in S1 as solvent, heat and extract in a water bath at 50°C for 3 hours to obtain an alcohol extract.

[0051] S3, vacuum concentrate the alcohol extract at 40°C using a rotary evaporator with a concentration ratio of 10:1 to obtain an acne-repairing extract.

[0052] Example 2

[0053] The plant-derived acne-repairing extract of the present invention is prepared according to the following steps:

[0054] S1, placing 1000 g of bitter melon, 500 g of Magnolia officinalis, and 50 g of Artemisia argyi in an oven at 45° C. for 24 hours, and crushing them together with a traditional Chinese medicine grinder to obtain a mixed powder.

[0055] S2, add 60% ethanol aqueous solution with a volume fraction of 10 times the mass of the mixed powder obtained in S1 as solvent, heat and extract in a water bath at 50°C for 3 hours to obtain an alcohol extract.

[0056] S3, vacuum concentrate the alcohol extract at 40°C using a rotary evaporator with a concentration ratio of 10:1 to obtain an acne-repairing extract.

[0057] Example 3

[0058] The plant-derived acne-repairing extract of the present invention is prepared according to the following steps:

[0059] S1, placing 300 g of bitter melon, 700 g of Magnolia officinalis, and 500 g of Artemisia argyi in an oven at 45° C. for 24 hours, and crushing them together with a traditional Chinese medicine grinder to obtain a mixed powder.

[0060] S2, add 60% ethanol aqueous solution with a volume fraction of 10 times the mass of the mixed powder obtained in S1 as solvent, heat and extract in a water bath at 50°C for 3 hours to obtain an alcohol extract.

[0061] S3, vacuum concentrate the alcohol extract at 40°C using a rotary evaporator with a concentration ratio of 10:1 to obtain an acne-repairing extract.

[0062] Example 4

[0063] Follow these steps to prepare your plant-derived acne-repairing extract:

[0064] S1, placing 1100 g of bitter melon and 600 g of Magnolia officinalis in an oven at 45° C. for 24 hours, and crushing them together with a traditional Chinese medicine grinder to obtain a mixed powder.

[0065] S2, add 60% ethanol aqueous solution with a volume fraction of 10 times the mass of the mixed powder obtained in S1 as solvent, heat and extract in a water bath at 50°C for 3 hours to obtain an alcohol extract.

[0066] S3, vacuum concentrate the alcohol extract at 40°C using a rotary evaporator with a concentration ratio of 10:1 to obtain an acne-repairing extract.

[0067] Example 5

[0068] Follow these steps to prepare your plant-derived acne-repairing extract:

[0069] S1, 1280 g of Magnolia officinalis and 300 g of Artemisia argyi are placed in an oven at 45° C. for 24 hours, and then crushed together using a traditional Chinese medicine grinder to obtain a mixed powder.

[0070] S2, add 60% ethanol aqueous solution with a volume fraction of 10 times the mass of the mixed powder obtained in S1 as solvent, heat and extract in a water bath at 50°C for 3 hours to obtain an alcohol extract.

[0071] S3, vacuum concentrate the alcohol extract at 40°C using a rotary evaporator with a concentration ratio of 10:1 to obtain an acne-repairing extract.

[0072] Example 6

[0073] Follow these steps to prepare your plant-derived acne-repairing extract:

[0074] S1, placing 1100 g of bitter melon and 500 g of wormwood in an oven at 45° C. for 24 hours, and crushing them together with a traditional Chinese medicine grinder to obtain a mixed powder.

[0075] S2, add 60% ethanol aqueous solution with a volume fraction of 10 times the mass of the mixed powder obtained in S1 as solvent, heat and extract in a water bath at 50°C for 3 hours to obtain an alcohol extract.

[0076] S3, vacuum concentrate the alcohol extract at 40°C using a rotary evaporator with a concentration ratio of 10:1 to obtain an acne-repairing extract.

[0077] Example 7

[0078] Prepare the acne-repairing facial mask of the present invention according to the following method:

[0079] Weigh 3 parts of 1,3-butylene glycol, 1 part of glycerol, 0.3 parts of carbomer U21, 0.5 parts of dipotassium glycyrrhizinate, 0.2 parts of allantoin, 0.5 parts of bilberry seed oil, and an appropriate amount of deionized water at 100°C, and homogenize at low speed for 2 minutes;

[0080] The mixture was cooled to 50°C with stirring, and 0.12 parts of aminomethyl propanol was added dropwise while stirring;

[0081] Add 1 part of niacinamide, 2 parts of macromolecular papain, 50 parts of the acne-repairing extract prepared in Example 1 and 0.1 parts of madecassoside, add deionized water to make the system 100 parts by mass, stir evenly, and prepare an acne-repairing facial mask liquid.

[0082] The above-mentioned acne-removing and repairing facial mask liquid is filled with 25g according to the conventional method, and sealed to obtain the acne-removing and repairing facial mask.

[0083] Example 8

[0084] Prepare the acne-repairing facial mask of the present invention according to the following method:

[0085] Weigh 3 parts of 1,3-butylene glycol, 1 part of glycerol, 0.3 parts of carbomer U21, 0.5 parts of dipotassium glycyrrhizinate, 0.2 parts of allantoin, 0.5 parts of bilberry seed oil, and an appropriate amount of deionized water at 100°C, and homogenize at low speed for 2 minutes;

[0086] The mixture was cooled to 50°C with stirring, and 0.12 parts of aminomethyl propanol was added dropwise while stirring;

[0087] Add 1 part of niacinamide, 2 parts of macromolecular papain, 30 parts of the acne-repairing extract prepared in Example 1 and 0.1 parts of madecassoside, add deionized water to make the system 100 parts by mass, stir evenly, and prepare an acne-repairing facial mask liquid.

[0088] The above-mentioned acne-removing and repairing facial mask liquid is filled with 25g according to the conventional method, and sealed to obtain the acne-removing and repairing facial mask.

[0089] Example 9

[0090] Prepare the acne-repairing facial mask of the present invention according to the following method:

[0091] Weigh 3 parts of 1,3-butylene glycol, 1 part of glycerol, 0.3 parts of carbomer U21, 0.5 parts of dipotassium glycyrrhizinate, 0.2 parts of allantoin, 0.5 parts of bilberry seed oil, and an appropriate amount of deionized water at 100°C, and homogenize at low speed for 2 minutes;

[0092] The mixture was cooled to 50°C with stirring, and 0.12 parts of aminomethyl propanol was added dropwise while stirring;

[0093] Add 1 part of niacinamide, 2 parts of macromolecular papain, 10 parts of the acne-repairing extract prepared in Example 1 and 0.1 parts of madecassoside, add deionized water to make the system 100 parts by mass, stir evenly, and prepare an acne-repairing facial mask liquid.

[0094] The above-mentioned acne-removing and repairing facial mask liquid is filled with 25g according to the conventional method, and sealed to obtain the acne-removing and repairing facial mask.

[0095] Example 10

[0096] Prepare the acne-repairing facial mask of the present invention according to the following method:

[0097] Weigh 3 parts of 1,3-butylene glycol, 1 part of glycerol, 0.3 parts of carbomer U21, 0.5 parts of dipotassium glycyrrhizinate, 0.2 parts of allantoin, 0.5 parts of bilberry seed oil, and an appropriate amount of deionized water at 100°C, and homogenize at low speed for 2 minutes;

[0098] The mixture was cooled to 50°C with stirring, and 0.12 parts of aminomethyl propanol was added dropwise while stirring;

[0099] Add 1 part of niacinamide, 2 parts of macromolecular papain, 10 parts of the acne-repairing extract prepared in Example 2 and 0.1 parts of madecassoside, add deionized water to make the system 100 parts by mass, stir evenly, and prepare an acne-repairing facial mask liquid.

[0100] The above-mentioned acne-removing and repairing facial mask liquid is filled with 25g according to the conventional method, and sealed to obtain the acne-removing and repairing facial mask.

[0101] Embodiment 11

[0102] Prepare the acne-repairing facial mask of the present invention according to the following method:

[0103] Weigh 3 parts of 1,3-butylene glycol, 1 part of glycerol, 0.3 parts of carbomer U21, 0.5 parts of dipotassium glycyrrhizinate, 0.2 parts of allantoin, 0.5 parts of bilberry seed oil, and an appropriate amount of deionized water at 100°C, and homogenize at low speed for 2 minutes;

[0104] The mixture was cooled to 50°C with stirring, and 0.12 parts of aminomethyl propanol was added dropwise while stirring;

[0105] Add 1 part of niacinamide, 2 parts of macromolecular papain, 30 parts of the acne-repairing extract prepared in Example 2 and 0.1 parts of madecassoside, add deionized water to make the system 100 parts by mass, stir evenly, and prepare an acne-repairing facial mask liquid.

[0106] The above-mentioned acne-removing and repairing facial mask liquid is filled with 25g according to the conventional method, and sealed to obtain the acne-removing and repairing facial mask.

[0107] Example 12

[0108] Prepare the acne-repairing facial mask of the present invention according to the following method:

[0109] Weigh 3 parts of 1,3-butylene glycol, 1 part of glycerol, 0.3 parts of carbomer U21, 0.5 parts of dipotassium glycyrrhizinate, 0.2 parts of allantoin, 0.5 parts of bilberry seed oil, and an appropriate amount of deionized water at 100°C, and homogenize at low speed for 2 minutes;

[0110] The mixture was cooled to 50°C with stirring, and 0.12 parts of aminomethyl propanol was added dropwise while stirring;

[0111] Add 1 part of niacinamide, 2 parts of macromolecular papain, 50 parts of the acne-repairing extract prepared in Example 2 and 0.1 parts of madecassoside, add deionized water to make the system 100 parts by mass, stir evenly, and prepare an acne-repairing facial mask liquid.

[0112] The above-mentioned acne-removing and repairing facial mask liquid is filled with 25g according to the conventional method, and sealed to obtain the acne-removing and repairing facial mask.

[0113] Embodiment 13

[0114] Prepare the acne-repairing facial mask of the present invention according to the following method:

[0115] Weigh 3 parts of 1,3-butylene glycol, 1 part of glycerol, 0.3 parts of carbomer U21, 0.5 parts of dipotassium glycyrrhizinate, 0.2 parts of allantoin, 0.5 parts of bilberry seed oil, and an appropriate amount of deionized water at 100°C, and homogenize at low speed for 2 minutes;

[0116] The mixture was cooled to 50°C with stirring, and 0.12 parts of aminomethyl propanol was added dropwise while stirring;

[0117] Add 1 part of niacinamide, 2 parts of macromolecular papain, 50 parts of the acne-repairing extract prepared in Example 3 and 0.1 parts of madecassoside, add deionized water to make the system 100 parts by mass, stir evenly, and prepare an acne-repairing facial mask liquid.

[0118] The above-mentioned acne-removing and repairing facial mask liquid is filled with 25g according to the conventional method, and sealed to obtain the acne-removing and repairing facial mask.

[0119] Embodiment 14

[0120] Prepare the acne-repairing facial mask of the present invention according to the following method:

[0121] Weigh 3 parts of 1,3-butylene glycol, 1 part of glycerol, 0.3 parts of carbomer U21, 0.5 parts of dipotassium glycyrrhizinate, 0.2 parts of allantoin, 0.5 parts of bilberry seed oil, and an appropriate amount of deionized water at 100°C, and homogenize at low speed for 2 minutes;

[0122] The mixture was cooled to 50°C with stirring, and 0.12 parts of aminomethyl propanol was added dropwise while stirring;

[0123] Add 1 part of niacinamide, 2 parts of macromolecular papain, 30 parts of the acne-repairing extract prepared in Example 3 and 0.1 parts of madecassoside, add deionized water to make the system 100 parts by mass, stir evenly, and prepare an acne-repairing facial mask liquid.

[0124] The above-mentioned acne-removing and repairing facial mask liquid is filled with 25g according to the conventional method, and sealed to obtain the acne-removing and repairing facial mask.

[0125] Embodiment 15

[0126] Prepare the acne-repairing facial mask of the present invention according to the following method:

[0127] Weigh 3 parts of 1,3-butylene glycol, 1 part of glycerol, 0.3 parts of carbomer U21, 0.5 parts of dipotassium glycyrrhizinate, 0.2 parts of allantoin, 0.5 parts of bilberry seed oil, and an appropriate amount of deionized water at 100°C, and homogenize at low speed for 2 minutes;

[0128] The mixture was cooled to 50°C with stirring, and 0.12 parts of aminomethyl propanol was added dropwise while stirring;

[0129] Add 1 part of niacinamide, 2 parts of macromolecular papain, 10 parts of the acne-repairing extract prepared in Example 3 and 0.1 parts of madecassoside, add deionized water to make the system 100 parts by mass, stir evenly, and prepare an acne-repairing facial mask liquid.

[0130] The above-mentioned acne-removing and repairing facial mask liquid is filled with 25g according to the conventional method, and sealed to obtain the acne-removing and repairing facial mask.

[0131] Comparative Example 1

[0132] Prepare the acne-removing mask as follows:

[0133] Weigh 3 parts of 1,3-butylene glycol, 1 part of glycerol, 0.3 parts of carbomer U21, 0.5 parts of dipotassium glycyrrhizinate, 0.2 parts of allantoin, 0.5 parts of bilberry seed oil, and an appropriate amount of deionized water at 100°C, and homogenize at low speed for 2 minutes;

[0134] The mixture was cooled to 50°C with stirring, and 0.12 parts of aminomethyl propanol was added dropwise while stirring;

[0135] Add 1 part of niacinamide, 2 parts of macromolecular papain, 50 parts of the acne-repairing extract prepared in Example 4 and 0.1 parts of madecassoside, add deionized water to make the system 100 parts by mass, stir evenly, and prepare an acne-repairing facial mask liquid.

[0136] The above-mentioned acne-removing and repairing facial mask liquid is filled with 25g according to the conventional method, and sealed to obtain the acne-removing and repairing facial mask.

[0137] Comparative Example 2

[0138] Prepare the acne-removing mask as follows:

[0139] Weigh 3 parts of 1,3-butylene glycol, 1 part of glycerol, 0.3 parts of carbomer U21, 0.5 parts of dipotassium glycyrrhizinate, 0.2 parts of allantoin, 0.5 parts of bilberry seed oil, and an appropriate amount of deionized water at 100°C, and homogenize at low speed for 2 minutes;

[0140] The mixture was cooled to 50°C with stirring, and 0.12 parts of aminomethyl propanol was added dropwise while stirring;

[0141] Add 1 part of niacinamide, 2 parts of macromolecular papain, 50 parts of the acne-repairing extract prepared in Example 5 and 0.1 parts of madecassoside, add deionized water to make the system 100 parts by mass, stir evenly, and prepare an acne-repairing facial mask liquid.

[0142] The above-mentioned acne-removing and repairing facial mask liquid is filled with 25g according to the conventional method, and sealed to obtain the acne-removing and repairing facial mask.

[0143] Comparative Example 3

[0144] Prepare the acne-removing mask as follows:

[0145] Weigh 3 parts of 1,3-butylene glycol, 1 part of glycerol, 0.3 parts of carbomer U21, 0.5 parts of dipotassium glycyrrhizinate, 0.2 parts of allantoin, 0.5 parts of bilberry seed oil, and an appropriate amount of deionized water at 100°C, and homogenize at low speed for 2 minutes;

[0146] The mixture was cooled to 50°C with stirring, and 0.12 parts of aminomethyl propanol was added dropwise while stirring;

[0147] Add 1 part of niacinamide, 2 parts of macromolecular papain, 50 parts of the acne-repairing extract prepared in Example 6 and 0.1 parts of madecassoside, add deionized water to make the system 100 parts by mass, stir evenly, and prepare an acne-repairing facial mask liquid.

[0148] The above-mentioned acne-removing and repairing facial mask liquid is filled with 25g according to the conventional method, and sealed to obtain the acne-removing and repairing facial mask.

[0149] Example 16

[0150] 240 volunteers with acne on their faces were recruited and divided into 12 groups, each with 20 people. The masks prepared by Examples 7-15 and Comparative Examples 1-3 were used for 4 consecutive weeks, 3 times / week, to test the efficacy of the products. The improvement effect of the mask of the present invention on acne skin was evaluated by two methods: a consumer questionnaire and a VISA skin tester. The instrument detection indicators are skin texture, red area and pores, and the percentage ranking of the indicators in the same age group (automatically given by the instrument) is used for characterization. The higher the percentage, the higher the score of the indicator, indicating a higher health level.

[0151] By the attached Figure 1 It can be seen that after using the products of Examples 7-15, the average percentage of skin texture of the 9 groups of volunteers increased from the initial value of 60% to 87%, indicating that the acne-removing and repairing mask of the present invention can make the skin texture smoother, indicating that the skin inflammation pustules are discharged and the hair follicle abscess is improved. Combined with the standard light VISA images of individual volunteer cases, the facial skin conditions before and after use are compared (see Appendix Figure 2 , 3 ) It can be seen that acne scars are significantly lightened due to the smoother growth of new skin. The pore value gradually improved from the initial value of 3% to 26%, and the red area gradually improved from the initial value of 19% to 48%, indicating that the sebum is healthier, the pores are convergent, and the skin is more delicate and smoother than before treatment. The redness of the epidermis and superficial epidermis has also been significantly repaired, and the redness has obviously subsided, which is directly related to the reduction of skin inflammation and the enhancement of skin barrier repair. However, the acne skin of volunteers who used comparison products 1-3 did not improve.

[0152] According to the statistical results of the volunteer questionnaire (see Table 1 below), the acne-removing and repairing mask produced by the plant acne-removing extract of the present invention has obvious effects in four aspects: acne-removing and anti-inflammatory, mildness, fading acne marks, and repairing acne pits. In Comparative Example 1, due to the lack of the acne-removing component wormwood, its repair effect and soothing effect are not good. In Comparative Example 2, Magnolia officinalis and wormwood have certain soothing and antibacterial effects, but the prognosis and repair effects of acne are not obvious, and the acne-removing effect cannot be consolidated; in Comparative Example 3, 35% of users reported that there was no acne-removing effect. Only the acne-removing and repairing extract of the present invention, which is extracted from bitter melon, Magnolia officinalis, and wormwood, can effectively resist inflammation and inhibit bacteria, and remove acne marks.

[0153] Table 1 Statistical results of consumer usage survey

[0154]

[0155] The above is an explanation of the embodiments of the present invention. However, the present invention is not limited to the above embodiments. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention shall be included in the protection scope of the present invention.

Claims

1. A plant-derived acne-repairing extract, characterized in that: The acne-removing and repairing extract is composed of extracts of bitter melon, magnolia bark and wormwood, and in parts by mass, the bitter melon is 3 to 10 parts, the magnolia bark is 5 to 8 parts, and the wormwood is 0.5 to 5 parts. The acne-removing and repairing extract is an ethanol extract, and the volume fraction of ethanol in the solvent ethanol aqueous solution is at least 60%.

2. The method for preparing the acne-repairing extract according to claim 1, characterized in that: The steps include: (1) Dry bitter melon, Magnolia officinalis, and Artemisia argyi to a moisture content of 12%±2% and crush them; (2) using an ethanol aqueous solution of 5 to 15 times the mass of the dried and crushed bitter melon, magnolia bark, and wormwood as a solvent, extracting for 1 to 5 hours to obtain an ethanol extract, wherein the volume fraction of ethanol in the solvent ethanol aqueous solution is at least 60%; (3) Concentrating the alcohol extract to obtain an acne-repairing extract.

3. The preparation method according to claim 2, characterized in that: Bitter melon, Magnolia officinalis and mugwort are dried, crushed, extracted and concentrated together; or, bitter melon, Magnolia officinalis and mugwort are dried separately, crushed, extracted and concentrated together; or, bitter melon, Magnolia officinalis and mugwort are dried separately, crushed, extracted and concentrated together; or, bitter melon, Magnolia officinalis and mugwort are dried separately, crushed, extracted and concentrated together; or, bitter melon, Magnolia officinalis and mugwort are dried separately, crushed, extracted and concentrated and then mixed.

4. The preparation method according to claim 2, characterized in that: The drying temperature in step (1) is 40-60°C.

5. The preparation method according to claim 4, characterized in that: The drying temperature in step (1) is 45°C.

6. The preparation method according to claim 2, characterized in that: The drying time in step (1) is 16-32 hours.

7. The preparation method according to claim 6, characterized in that: The drying time in step (1) is 24 hours.

8. The preparation method according to claim 2, characterized in that: The extraction temperature in step (2) is 45-55°C.

9. The preparation method according to claim 8, characterized in that: The extraction temperature in step (2) is 50°C.

10. The preparation method according to claim 2, characterized in that: The extraction time in step (2) is 3 hours.

11. The preparation method according to claim 2, characterized in that: The concentration ratio of the alcohol extract in step (3) is 15:1-6:

1.

12. The preparation method according to claim 11, characterized in that: The concentration ratio of the alcohol extract in step (3) is 10:

1.

13. The preparation method according to claim 2, characterized in that: The concentration temperature in step (3) is 37-50°C.

14. The preparation method according to claim 13, characterized in that: The concentration temperature in step (3) is 40°C.

15. The acne-repairing extract prepared by the preparation method according to any one of claims 2 to 14.

16. An acne-removing and repairing facial mask liquid, characterized in that: Contains the acne-repairing extract as claimed in claim 1 or 15.

17. The acne-removing and repairing facial mask liquid according to claim 16, characterized in that: The acne-removing and repairing facial mask liquid contains, by mass percentage: 3-15% emollient, 0.1-2% thickener, 0-0.15% neutralizer, 0.5-5% keratin exfoliant, 10-50% of the acne-removing and repairing extract, 0.5-5% oil-control auxiliary acne-removing agent, 0.2-1% anti-inflammatory and soothing agent, 0.5-3% repair agent, 0-1% fragrance and / or pigment, and 20-85% deionized water.

18. The acne-removing and repairing facial mask liquid according to claim 17, characterized in that: The emollient is a polyol selected from one or more of propylene glycol, butylene glycol and glycerin.

19. The acne-removing and repairing facial mask liquid according to claim 18, characterized in that: The emollients are 1,3-butylene glycol and glycerin.

20. The acne-removing and repairing facial mask liquid according to claim 19, characterized in that: The mass ratio of 1,3-butanediol to glycerol is: (1-10):

1.

21. The acne-removing and repairing facial mask liquid according to claim 17, characterized in that: The thickener is selected from one or more of carbomer, acrylic acid (ester), pectin, hyaluronic acid, starch, sodium alginate and xanthan gum.

22. The acne-removing and repairing facial mask liquid according to claim 21, characterized in that: The thickener is Carbopol U21.

23. The acne-removing and repairing facial mask liquid according to claim 17, characterized in that: The neutralizing agent is selected from one or more of NaOH, KOH, aminomethyl propanol and triethanolamine.

24. The acne-removing and repairing facial mask liquid according to claim 23, characterized in that: The neutralizing agent is aminomethyl propanol.

25. The acne-removing and repairing facial mask liquid according to claim 17, characterized in that: The keratin exfoliating agent is an acid selected from one or more of VC, VC acetate, azelaic acid, ellagic acid, salicylic acid, fruit acid, and glycolic acid.

26. The acne-removing and repairing facial mask liquid according to claim 17, characterized in that: The keratin exfoliating agent is an enzyme selected from one or more of papain, lysozyme, and bromelain.

27. The acne-removing and repairing facial mask liquid according to claim 26, characterized in that: The keratin exfoliating agent is macromolecular papain.

28. The acne-removing and repairing facial mask liquid according to claim 17, characterized in that: The oil-controlling auxiliary acne-removing agent is niacinamide.

29. The acne-removing and repairing facial mask liquid according to claim 17, characterized in that: The anti-inflammatory and allergy-relieving agent is selected from one or more of prebiotics, plant fermentation filtrate, scutellaria baicalensis extract, gentian violet extract, bisabolol, licorice extract, Centella asiatica extract, allantoin, and peptides.

30. The acne-removing and repairing facial mask liquid according to claim 29, characterized in that: The anti-inflammatory and allergy-relieving agents are dipotassium glycyrrhizinate and allantoin.

31. The acne-removing and repairing facial mask liquid according to claim 30, characterized in that: In terms of mass percentage, dipotassium glycyrrhizinate is 0.5%, and allantoin is 0.2%.

32. The acne-removing and repairing facial mask liquid according to claim 17, characterized in that: The repairing agents are madecassoside and bilberry seed oil.

33. The acne-removing and repairing facial mask liquid according to claim 32, characterized in that: The mass ratio of madecassoside to bilberry seed oil is: (0.1-1):(0.5-2).

34. A facial mask, characterized in that: The facial mask patch comprises a facial mask base fabric and the facial mask liquid as described in any one of claims 16-33.

35. The facial mask patch according to claim 34, characterized in that: The amount of mask liquid in the mask is 20-30g.

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