Preparation method for porous implant grafting and printing

Abstract

An embodiment of the present application provides a preparation method for grafting and printing a porous implant, including: laying tantalum metal powder on a substrate, melting the tantalum metal powder using a first laser and a second laser to obtain the root of the implant; scanning the root of the implant to obtain the contour of the root of the implant; covering the root of the implant with titanium alloy powder; determining the printing origin of the neck of the implant according to the contour of the root of the implant; printing the neck of the implant, starting from the printing origin, melting the titanium alloy powder using the first laser or the second laser to obtain the finished implant. Through multiple processing methods, the present application fuses and prints different types of metal powders to be formed, realizes the processing of implants by combining the material characteristics of different materials, and can obtain a porous implant with excellent comprehensive performance and high practicability.

Description

Technical Field

[0001] This application relates to the technical field of medical biomaterial preparation, and particularly to a preparation method for grafting and printing porous implants. Background Art

[0002] Dental implant technology is one of the main methods for repairing tooth loss and damage. Tantalum metal is widely used in the field of biomaterials, such as bone repair and implant manufacturing, due to its extremely high corrosion resistance, extremely low thermal expansion coefficient, and excellent biocompatibility.

[0003] Existing metal dental implants include single-material types and composite-material types. For single-material implants, such as titanium alloy or tantalum metal, when using titanium alloy, its performance as a biomaterial is limited, while when using excellent-performance tantalum metal, the cost is high, which is not conducive to the promotion and popularization of products. However, for composite-material implants, although they can combine the advantages of both materials, they are often two-piece implants that require two surgeries to complete implantation, with obvious defects. Summary of the Invention

[0004] In view of the above, it is necessary to propose a preparation method for grafting and printing porous implants to obtain porous implants with excellent comprehensive performance and high practicability.

[0005] A preparation method for grafting and printing porous implants includes the following steps:

[0006] Lay tantalum metal powder on a substrate, and use a first laser and a second laser to melt the tantalum metal powder to obtain the root of the implant;

[0007] Scan the root of the implant to obtain the contour of the root of the implant;

[0008] Cover the root of the implant with titanium alloy powder;

[0009] Determine the printing origin of the neck of the implant according to the contour of the root of the implant;

[0010] Print the neck of the implant, starting from the printing origin, and use the first laser or the second laser to melt the titanium alloy powder to obtain the finished implant.

[0011] In a possible implementation manner, the step of laying tantalum metal powder on the substrate includes:

[0012] Control a powder spreading device to lay the tantalum metal powder on the substrate, and the thickness of the tantalum metal powder is 30 - 50 μm.

[0013] In a possible implementation manner, the step of melting the tantalum metal powder to obtain the root of the implant includes:

[0014] Control the deflection of the scanning galvanometer to melt the tantalum metal powder with the printing laser to obtain the root of the implant.

[0015] In a possible implementation manner, the step of controlling the deflection of the scanning galvanometer to melt the tantalum metal powder with the printing laser to obtain the root of the implant further includes:

[0016] Control the laser beam to scan the tantalum metal powder layer by layer to form a structure with a dense center and porous unit cells on the outside.

[0017] In a possible implementation manner, the printing laser includes a first laser and a second laser. The first laser preheats the tantalum metal powder, and the second laser melts the tantalum metal powder.

[0018] In a possible implementation manner, before the step of printing the neck of the implant, starting from the printing origin point, melting the titanium alloy powder with the first laser or the second laser to obtain the finished implant, it includes:

[0019] Perform multiple scans to preheat the titanium alloy powder.

[0020] In a possible implementation manner, the step of covering the root of the implant with the titanium alloy powder includes:

[0021] Cover the root of the implant with titanium alloy powder having a particle size of 15 - 53 μm, wherein the covering height of the titanium alloy powder covering the root of the implant is 30 - 50 μm.

[0022] In a possible implementation manner, the root of the implant includes a first thread structure, a porous structure, and a second thread structure connected in sequence.

[0023] In a possible implementation manner, the porous structure includes a dense central part and an outer layer part, and the outer layer part includes porous unit cells.

[0024] In a possible implementation manner, the tantalum metal powder is at the first station, the titanium alloy powder is at the second station, and after the root of the implant is formed at the first station, it is transferred to the second station.

[0025] A method for grafting and printing a porous implant proposed in this application grafts and prints a finished implant from tantalum metal and titanium alloy through a secondary processing method, combines the material characteristics of the two materials, and realizes the preparation of a porous implant with excellent comprehensive performance, high practicability, and appropriate cost. Description of the Drawings

[0026] Figure 1It is a schematic flowchart of the steps of a method for preparing a porous implant according to an embodiment of the present application.

[0027] Figure 2 It is a schematic flowchart of the method for preparing a porous implant according to another embodiment of the present application.

[0028] Figure 3 Is Figure 1 It is a schematic structural diagram of the finished implant obtained by the method for preparing a porous implant shown.

[0029] Figure 4 Is Figure 3 It is a schematic cross-sectional structural diagram of the finished implant shown.

[0030] Description of main element symbols

[0031] Finished implant 100

[0032] Root of implant 10

[0033] First thread structure 11

[0034] Porous structure 12

[0035] Central part 121

[0036] Outer layer part 122

[0037] Second thread structure 13

[0038] Neck of implant 20 Detailed implementation manners

[0039] In order to make the objectives, technical solutions and advantages of the present application clearer, the present application will be further described in detail below with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are only used to explain the present application and are not used to limit the present application. All other embodiments obtained by those of ordinary skill in the art based on the embodiments in the present application without creative efforts shall fall within the scope of protection of the present application.

[0040] In the description of the present application, it should be understood that the orientation or positional relationship indicated by the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", etc. is based on the orientation or positional relationship shown in the drawings. It is only for the convenience of describing the present application and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation. Therefore, it should not be construed as a limitation to the present application. In addition, the terms "first" and "second" are only used for descriptive purposes and cannot be understood as indicating or implying relative importance or implicitly specifying the quantity of the indicated technical features. Thus, the features defined with "first" and "second" may explicitly or implicitly include one or more of the said features. In the description of the present application, "a plurality of" means two or more, unless otherwise specifically defined.

[0041] In the description of the present application, it should be noted that unless otherwise clearly specified and defined, the terms "mounted", "connected" and "coupled" shall be construed broadly. For example, it may be a fixed connection, a detachable connection, or an integral connection; it may be a mechanical connection, an electrical connection or a connection capable of mutual communication; it may be directly connected, or indirectly connected through an intermediate medium, and it may be the internal communication of two elements or the interaction relationship between two elements. For those of ordinary skill in the art, the specific meanings of the above terms in the present application can be understood according to specific circumstances.

[0042] In the present application, unless otherwise clearly specified and defined, the first feature being "on" or "under" the second feature may include the direct contact between the first and second features, or may include the situation where the first and second features are not in direct contact but in contact through additional features therebetween. Moreover, the first feature being "above", "over" and "on top of" the second feature includes that the first feature is directly above and obliquely above the second feature, or merely means that the horizontal height of the first feature is higher than that of the second feature. The first feature being "under", "beneath" and "underneath" the second feature includes that the first feature is directly below and obliquely below the second feature, or merely means that the horizontal height of the first feature is lower than that of the second feature.

[0043] The following disclosure provides many different embodiments or examples for implementing different structures of the present application. To simplify the disclosure of the present application, the components and settings of specific examples are described below. Of course, they are only examples and are not intended to limit the present application. In addition, the present application may repeat reference numerals and / or reference letters in different examples. Such repetition is for the purpose of simplification and clarity, and does not itself indicate the relationship between the various embodiments and / or settings discussed. In addition, the present application provides examples of various specific processes and materials, but those of ordinary skill in the art can be aware of the application of other processes and / or the use of other materials.

[0044] Please refer to Figure 1 , the first embodiment of the present application provides a method for preparing a porous implant graft by printing, including the following steps:

[0045] S10: Lay tantalum metal powder on the substrate, and use the first laser and the second laser to melt the tantalum metal powder to obtain the root 10 of the implant.

[0046] Please refer to Figure 3 , it should be explained that the root 10 of the implant is the part implanted into the human tissue, and the part outside the human tissue is the neck 20 of the implant. Therefore, tantalum metal that has no negative impact on human health and no rejection reaction is used. The outer edge of the root 10 of the implant has a threaded structure to firmly connect to the human tissue and ensure the use strength. In this embodiment, the 3D model of the root 10 of the implant can be designed by CAD software first, the placement position and slicing operation can be set by magics software, and then the path planning can be carried out according to the structural characteristics of the root 10 of the implant. After setting the corresponding printing parameters, control the powder spreading device of the 3D printer to lay the tantalum metal powder on the forming substrate of the printer, and then melt the powder to obtain the root 10 of the implant.

[0047] S20: Scan the root 10 of the implant to obtain the contour of the root 10 of the implant.

[0048] In an embodiment of the present application, a CCD scanning device can be used to scan the root 10 of the implant to obtain the formed contour of the root 10 of the implant.

[0049] S30: Cover the root 10 of the implant with titanium alloy powder.

[0050] In an embodiment of the present application, the titanium alloy powder can be set on the forming substrate of another station, or after recovering the tantalum metal powder on the forming substrate of the original station, the titanium alloy powder can be laid on the same substrate. Similarly, control the powder spreading device of the 3D printer to lay the titanium alloy powder.

[0051] S40: Determine the printing origin of the neck 20 of the implant according to the contour of the root 10 of the implant.

[0052] In an embodiment of the present application, a preset algorithm can be used to calculate the contour of the root 10 of the implant to accurately determine the printing origin of the neck 20 of the implant, so as to ensure the printing accuracy at the connection between the root 10 of the implant and the neck 20 of the implant. In this embodiment, a CCD scanning device is used to scan the contour and determine the printing origin, and the deviation of the grafting accuracy between the root 10 of the implant and the neck 20 of the implant can be controlled within 0.1 mm.

[0053] S50: Print the neck 20 of the implant. Starting from the printing origin, the titanium alloy powder is melted by the first laser or the second laser to obtain the finished implant 100.

[0054] Since the titanium alloy powder is coated on the root 10 of the implant, the titanium alloy powder after melting can firmly fix the formed neck 20 of the implant on the root 10 of the implant, realizing the finished implant 100 formed by grafting two materials.

[0055] In an embodiment, laying tantalum metal powder on the substrate in step S10 includes controlling the powder laying device to lay tantalum metal powder on the substrate, and the thickness of the tantalum metal powder is 30 - 50 μm.

[0056] In an embodiment, melting the tantalum metal powder in step S10 to obtain the root 10 of the implant includes:

[0057] Controlling the deflection of the scanning galvanometer to melt the tantalum metal powder with the printing laser to obtain the root 10 of the implant. In this embodiment, the angle of the laser is changed by adjusting the angle of the scanning galvanometer, so as to melt the tantalum metal powder along a preset path.

[0058] Please refer to Figure 4 , in an embodiment, the step of controlling the deflection of the scanning galvanometer to melt the tantalum metal powder with the printing laser to obtain the root 10 of the implant further includes:

[0059] Controlling the laser beam to scan the tantalum metal powder layer by layer to form a structure with a dense center and porous crystal cells on the outside.

[0060] The laser scans layer by layer according to the slices and paths pre-made by the software. The porous crystal cells form a porous structure 12, and the porous structure 12 is located in the middle section of the root 10 of the implant. Both ends of the root 10 of the implant are still thread structures. The porous structure 12 can effectively promote tissue growth, thereby firmly fixing the root 10 of the implant on the bone tissue. At the same time, the root 10 of the implant is relatively rough, while the neck 20 of the implant is relatively smooth, similar to the outer surface of a healthy tooth. The smooth neck can avoid the attachment and growth of bacteria during use and is convenient for cleaning, thereby improving the comprehensive performance of the implant.

[0061] In one embodiment, the printing laser includes a first laser and a second laser. The first laser preheats the tantalum metal powder, and the second laser melts the tantalum metal powder.

[0062] In this embodiment, the beam of the first laser is thicker to efficiently preheat the tantalum metal powder, and the beam of the second laser is thinner to directly melt the tantalum metal powder. The thinner beam can improve the printing accuracy. Since tantalum has a high melting point, the first laser and the second laser are used simultaneously for hot melting.

[0063] Please refer to Figure 2 , in one embodiment, before the step of processing the titanium alloy powder with the printing origin as the starting point to obtain the finished implant 100, it may include:

[0064] S41: Perform multiple scans to preheat the titanium alloy powder.

[0065] The melting point of titanium alloy is slightly lower than that of tantalum. Therefore, using one of the first laser or the second laser can meet the temperature requirements for hot melting.

[0066] In this embodiment, the diameter of the laser beam for melting the titanium alloy powder can be 70 - 120 μm.

[0067] In one embodiment, covering the root 10 of the implant with the titanium alloy powder may specifically include:

[0068] Cover the root 10 of the implant with titanium alloy powder having a particle size of 15 - 53 μm, where the covering height of the titanium alloy powder covering the root 10 of the implant is 30 - 50 μm.

[0069] Please continue to refer to Figure 3 , in one embodiment, the root 10 of the implant includes a first thread structure 11, a porous structure 12, and a second thread structure 13 connected in sequence. Among them, the first thread structure 11 is provided at one end away from the implant neck 20, and its property is approximately conical. The outer circumferential shapes of the second thread structure 13 and the porous structure 12 are approximately cylindrical.

[0070] Please continue to refer to Figure 4 , in one embodiment, the porous structure 12 includes a dense central part 121 and an outer layer part 122. The outer layer part 122 includes porous unit cells. The dense central part 121 plays a main supporting role, and the porous unit cell structure in the outer layer part 122 is conducive to tissue passing through and promoting its growth, thus playing the role of firm positioning.

[0071] In one embodiment, the tantalum metal powder is at the first station, and the titanium alloy powder is at the second station. After the root 10 of the implant is formed at the first station, it is transferred to the second station. The first station and the second station can be different stations, or the tantalum metal powder in the first station can be recycled, the first station can be cleaned and then used as the second station. The present application does not limit the specific method, aiming to realize the forming of two different powders to be formed.

[0072] The tantalum metal powder includes tantalum metal powder, and the titanium alloy powder includes titanium alloy powder. Tantalum metal is used to make the root 10 of the implant. This material has excellent biocompatibility and can promote the rapid ingrowth of tissues. Titanium alloy has the characteristics of high strength, good rigidity and high cost performance. The present application combines the advantages of the two materials, makes full use of strengths and avoids weaknesses, improves the performance of the implant while controlling the cost, and has practicability.

[0073] For those skilled in the art, it is obvious that the present application is not limited to the details of the above exemplary embodiments, and without departing from the spirit or basic characteristics of the present application, the present application can be implemented in other specific forms. Therefore, from any point of view, the embodiments should be regarded as exemplary and non-limiting.

[0074] The above embodiments are only used to illustrate the technical solutions of the present application and not to limit them. Although the present application has been described in detail with reference to the preferred embodiments, those of ordinary skill in the art should understand that the technical solutions of the present application can be modified or equivalently replaced without departing from the spirit and scope of the technical solutions of the present application.

Claims

1. A preparation method for grafting and printing a porous implant, characterized in that, The method includes the following steps: Lay tantalum metal powder on a substrate, use a first laser to emit a first laser to preheat the tantalum metal powder, and use a second laser to emit a second laser to melt the tantalum metal powder to obtain a root of an implant, wherein the beam of the first laser is thicker than the beam of the second laser; Scan the root of the implant to obtain the contour of the root of the implant; Cover the root of the implant with titanium alloy powder. The step of covering the root of the implant with titanium alloy powder includes: covering the root of the implant with titanium alloy powder having a particle size of 15 - 53 μm, and the covering height of the titanium alloy powder covering the root of the implant is 30 - 50 μm; Determine the printing origin of the neck of the implant according to the contour of the root of the implant; Print the neck of the implant. Starting from the printing origin, use the first laser or the second laser to thermally melt the titanium alloy powder to obtain a finished implant.

2. The method for preparing a porous implant by grafting and printing according to claim 1, wherein, The step of laying tantalum metal powder on the substrate includes: Controlling a powder laying device to lay the tantalum metal powder on the substrate, and the thickness of the tantalum metal powder is 30 - 50 μm.

3. The method for preparing a porous implant by grafting and printing according to claim 1, wherein, The step of thermally melting the tantalum metal powder to obtain the root of the implant includes: Controlling a scanning galvanometer to deflect so that a printing laser melts the tantalum metal powder to obtain the root of the implant.

4. The method for preparing a porous implant by grafting and printing according to claim 3, characterized in that, The step of controlling the scanning galvanometer to deflect so that the printing laser melts the tantalum metal powder to obtain the root of the implant further includes: Controlling the laser beam to scan the tantalum metal powder layer by layer to form a structure with a dense center and porous cells on the outside.

5. The method for preparing a porous implant by grafting and printing according to claim 1, characterized in that, Before the step of printing the neck of the implant, starting from the printing origin, using the first laser or the second laser to thermally melt the titanium alloy powder to obtain a finished implant, it includes: Performing multiple scans to preheat the titanium alloy powder.

6. The method for preparing a porous implant by grafting and printing according to claim 1, characterized in that, The root of the implant includes a first thread structure, a porous structure, and a second thread structure connected in sequence.

7. The method for preparing a porous implant by grafting and printing according to claim 6, characterized in that, The porous structure includes a dense central part and an outer layer part, and the outer layer part includes porous cells.

8. The method for preparing a porous implant by grafting and printing according to claim 1, wherein The tantalum metal powder is at a first station, the titanium alloy powder is at a second station, and after the root of the implant is formed at the first station, it is transferred to the second station.

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