Liquid transfer device
By using components such as multi-channel switching valves, connecting pipelines, inert gas emission components, and liquid level sensors in the liquid transfer device, the problems of liquid reagent residue and corrosion are solved, and high-precision liquid transfer is achieved.
Patent Information
- Application Number
- CN202310638175.4
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2023-05-31
- Publication Date
- 2026-02-06
- Estimated Expiration
- 2043-05-31
AI Technical Summary
In existing technologies, water- and oxygen-sensitive and highly corrosive liquid reagents are prone to remain in the extraction and discharge pipelines during the transfer process, leading to syringe corrosion and reduced liquid transfer accuracy.
The system employs a multi-channel switching valve, syringe, connecting pipeline, and inert gas discharge assembly. The liquid is temporarily stored through the connecting pipeline, and residual liquid is discharged using the inert gas discharge assembly. Combined with a liquid level sensor and buffer container, the liquid volume is controlled. Inert gas is used to maintain the pressure inside the source container to avoid liquid residue and corrosion.
It effectively avoids liquid residue in the transfer device, prevents corrosion, and improves the accuracy of liquid transfer precision and quantity.
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Figure CN116637667B_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The present application relates to the technical field of chemical liquid delivery, in particular to a liquid transfer device. BACKGROUND
[0002] In the process of scientific research, it is inevitable to add various liquid reagents which are sensitive to water and oxygen and have strong corrosivity into a reaction flask. Since the liquid reagent solution is prone to react with water and oxygen in the air to cause the deterioration of the drug, it is necessary to completely isolate oxygen during storage and transfer. In addition, the high corrosivity of the liquid reagent also requires that the reagent cannot be left in the transfer device for a long time.
[0003] The related art usually uses various pumps such as high-precision syringe pumps, peristaltic pumps and gear pumps to transfer liquid reagents which are sensitive to water and oxygen and have strong corrosivity. Among them, the gear pump and the peristaltic pump can realize continuous liquid delivery, and the high-precision syringe pump realizes intermittent liquid transfer by cooperating the syringe with the multi-channel valve. The high-precision syringe pump takes the syringe itself as a liquid temporary storage container, switches the valve to the valve connected to the liquid to be extracted, forms a vacuum when pulling the syringe piston to extract the liquid into the syringe, and then pushes the temporarily stored liquid in the syringe out after switching different valves.
[0004] Since the high-precision syringe pump needs to be connected to the reagent bottle in actual use, the liquid reagent enters the syringe from top to bottom, and the liquid is also pushed from bottom to top during discharge. Since the connecting pipeline has a certain length, part of the extracted liquid will be left in the extraction pipeline and cannot all reach the syringe; when the syringe piston is pushed to the end during discharge, part of the liquid will be left in the discharge pipeline and cannot all be discharged. In other words, due to the influence of the extraction and discharge pipelines, the liquid will be left in the syringe, which will further seriously corrode the high-precision syringe pump.
[0005] Therefore, effectively avoiding the residual liquid in the liquid transfer device is a technical problem to be solved by those skilled in the art. SUMMARY
[0006] The present application provides a liquid transfer device which can effectively avoid the residual liquid in the liquid transfer device.
[0007] To solve the above technical problems, the present application provides a liquid transfer device, which comprises a multi-channel switching valve, a syringe, a connecting pipeline and an inert gas discharge assembly.
[0008] The multi-channel switching valve comprises a common port, a plurality of interfaces and a switcher; the connecting pipeline temporarily stores the liquid to be transferred, and its length is determined according to the capacity of the liquid to be transferred and the condition that the liquid to be transferred does not enter the syringe;
[0009] The injector and the inert gas discharge assembly are connected to a common port at one end of the multi-channel switch valve through the connecting pipeline, and the other end of the multi-channel switch valve is connected to the source container and the target container through respective interfaces; the injector and the inert gas discharge assembly are in communication with the source container and the target container through the connecting pipeline, the common port, the switch valve and the corresponding interfaces;
[0010] The inert gas discharge assembly delivers inert gas outward through the connecting pipeline; the injector transfers the liquid to be transferred from the source container to the target container through the connecting pipeline and the multi-channel switch valve.
[0011] Optionally, a buffer container and a liquid level sensor are further included;
[0012] The connecting pipeline includes a first connecting pipeline and a second connecting pipeline; the buffer container is arranged between the first connecting pipeline and the second connecting pipeline;
[0013] One end of the first connecting pipeline is connected to the injector and the inert gas discharge assembly, and the other end is connected to one end of the buffer container; one end of the second connecting pipeline is connected to the other end of the buffer container, and the other end is connected to the common port;
[0014] The liquid level sensor is arranged between the buffer container and the multi-channel switch valve and is used to measure the liquid level in the second connecting pipeline;
[0015] The buffer container is used to temporarily store the liquid drawn from the source container.
[0016] Optionally, the liquid level sensor is installed at a target position of the second connecting pipeline.
[0017] Optionally, the number of interfaces of the multi-channel switch valve is equal to the sum of the number of source containers and the number of target containers.
[0018] Optionally, the inert gas discharge assembly includes a gas on-off switch and an inert gas source with a pressure regulating function;
[0019] The inert gas source is used to output inert gas and adjust the pressure of the output gas according to the current gas pressure demand;
[0020] One end of the gas on-off switch is connected to the inert gas source, and the other end is connected to one end of the connecting pipeline, for controlling whether the inert gas is delivered into the connecting pipeline.
[0021] Optionally, the gas on-off switch is a first electromagnetic valve.
[0022] Optionally, the gas on-off switch is a manual switch valve.
[0023] Optionally, the liquid transfer device further comprises a pressure maintaining pipeline.
[0024] One end of the pressure maintaining pipeline is connected to the inert gas discharge assembly, and the other end is connected to the source container.
[0025] The pressure maintaining pipeline is used to deliver inert gas into the source container to maintain the positive pressure in the source container.
[0026] Optionally, a pressure regulating valve can be added to the pressure maintaining pipeline to control the gas pressure of the pressure maintaining pipeline.
[0027] Optionally, the pressure maintaining pipeline is provided with the same number of gas on-off switches as the source containers.
[0028] As can be seen from the above technical solution, the connecting pipeline is used as a temporary storage container for the liquid to be transferred, and the liquid to be transferred does not need to enter the syringe, which can effectively solve the problem of corrosion of the syringe caused by the residual liquid in the syringe. The inert gas discharge assembly is added between the multi-channel switching valve and the syringe, and the residual liquid in the connecting pipeline can be discharged by delivering inert gas into the connecting pipeline. In this way, there is no liquid residual in the connecting pipeline and the syringe, which can effectively avoid the residual liquid in the liquid transfer device, thereby effectively avoiding the corrosion problem of the liquid transfer device caused by the strong corrosive liquid. Further, the residual liquid is completely blown into the target container by the inert gas, which is also beneficial to improve the precision of the liquid transfer amount. BRIEF DESCRIPTION OF DRAWINGS
[0029] In order to more clearly illustrate the embodiments of the present application, the drawings needed in the embodiments will be briefly introduced below. Obviously, the drawings in the following description are only some embodiments of the present application, and other drawings can be obtained by those skilled in the art without creative labor.
[0030] Figure 1 A structure schematic diagram of an embodiment of the liquid transfer device provided by the present application;
[0031] Figure 2 A structure schematic diagram of another embodiment of the liquid transfer device provided by the present application;
[0032] Figure 3 A structure schematic diagram of another embodiment of the liquid transfer device provided by the present application;
[0033] Figure 4 This is a schematic diagram of a structure in an embodiment of the liquid transfer device provided in this invention. Detailed Implementation
[0034] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments in this application, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of this application.
[0035] The terms "first," "second," etc., in the specification, claims, and accompanying drawings of this application are used to distinguish different objects, not to describe a specific order. Furthermore, the terms "comprising" and "having," and any variations thereof, are intended to cover non-exclusive inclusion. For example, an apparatus comprising a series of structures or components is not limited to the listed components or structures, but may include components or structures not listed.
[0036] To enable those skilled in the art to better understand the technical solution of this application, various non-limiting embodiments of the technical solution of this application will be described below with reference to the accompanying drawings.
[0037] First, please refer to Figure 1 , Figure 1 This is a schematic diagram of one embodiment of the liquid transfer device provided in this embodiment. The liquid transfer device of this embodiment may include the following:
[0038] The liquid transfer device of this application is used to transfer liquid from a source container 11 to a target container 12. For ease of description, the liquid is referred to as the liquid to be transferred. The liquid to be transferred can be any liquid reagent, including water- and oxygen-sensitive and highly corrosive solutions, as well as non-corrosive ordinary liquids. The original container holding the liquid to be transferred is referred to as the source container 11, and the target location for the transfer of the liquid to be transferred is referred to as the target container 12. The source container 11 and the target container 12 can be any container capable of holding the liquid to be transferred, and the target container 12 is a reaction flask. The liquid transfer device can transfer liquid from multiple source containers 11 to one or more target containers 12, meaning that this application does not limit the number of source containers 11 and target containers 12.
[0039] In this embodiment, the liquid transfer device may include a multi-channel switching valve 2, a syringe 3, a connecting pipeline 4, and an inert gas emission assembly 5.
[0040] The multi-channel switching valve 2 can include a common port 21, a plurality of interfaces 22, and a switcher 23. One end of the switcher 23 is fixedly connected with the common port 21, and the other end is connected with one of the plurality of interfaces 22 according to actual needs. The number of the interfaces 22 can be selected according to actual needs, taking into account the liquid transfer efficiency and cost. The number of the interfaces of the multi-channel switching valve 2 is equal to the sum of the number of the source containers 11 and the number of the target containers 12. For example, the number of the source containers 11 is 2, and the number of the target containers 12 is 1. Therefore, the number of the interfaces of the multi-channel switching valve 2 is 3, and the multi-channel switching valve 2 is a 3-channel switching valve.
[0041] The connecting pipeline 4 is used for temporarily storing the liquid to be transferred. That is, the liquid to be transferred is first temporarily stored in the connecting pipeline 4 by the syringe 3 from the source container 11. When the pipeline is connected to the target container 12 by the multi-channel switching valve 2, the liquid to be transferred in the connecting pipeline 4 is pushed into the target container 12 by the syringe 3, and the liquid to be transferred does not enter the syringe 4. Correspondingly, the length of the connecting pipeline 4 is determined according to the volume of the liquid to be transferred and the condition that the liquid to be transferred does not enter the syringe 4. The material of the connecting pipeline 4 can be any pipeline suitable for transporting and storing the liquid to be transferred, such as glass or polytetrafluoroethylene. The present application does not make any limitation in this regard.
[0042] In the present embodiment, the syringe 3 transfers the liquid to be transferred from the source container 11 to the target container 12 through the connecting pipeline 4 and the multi-channel switching valve 2. The syringe 3 can be any injection device for extracting and pushing the liquid by the push-pull piston 31, and the present application does not make any limitation in this regard. The inert gas discharge assembly 5 can transport the inert gas outward through the connecting pipeline 4. The inert gas discharge assembly 5 can be a structure for outputting any inert gas, such as helium. The syringe 3 is connected to the common port 21 of the multi-channel switching valve 2 through the connecting pipeline 4. The other end of the multi-channel switching valve 2 is connected to the source container 11 and the target container 12 through the interfaces 22, respectively. The inert gas discharge assembly 5 is connected to the common port 21 of the multi-channel switching valve 2 through the connecting pipeline 4. The inert gas discharge assembly 5 is connected to the corresponding interface of the target container 12 through the switcher 23. In this way, the syringe 3 can be connected to the source container 11 or the target container 12 through the connecting pipeline 4, the common port 21, the switcher 23, and the corresponding interface, so as to realize the extraction of the liquid from the source container 11 by the syringe 3 and the pushing of the liquid into the target container 12. The inert gas discharged by the inert gas discharge assembly 5 can be transported to the connecting pipeline 4 and the target container 12.
[0043] Of course, the positions, sizes and types of the multi-channel switching valve 2, the syringe 3, the connecting pipeline 4 and the inert gas discharge assembly 5 can be flexibly adjusted according to the actual physical space and internal device structure of the liquid transfer device, and the present application does not make any limitation in this regard.
[0044] In the technical solution provided in the present embodiment, the connecting pipeline is used as a temporary storage container for the liquid to be transferred, and the liquid to be transferred does not need to enter the syringe, which can effectively solve the problem that the liquid to be transferred is corroded in the syringe. The inert gas discharge assembly is added between the multi-channel switching valve and the syringe, and the liquid remaining in the connecting pipeline can be discharged by conveying inert gas to the connecting pipeline. In this way, there is no liquid remaining in the connecting pipeline and the syringe, which can effectively avoid the problem that the liquid to be transferred remains in the liquid transfer device, thereby effectively avoiding the corrosion problem of the liquid transfer device itself caused by the strong corrosive liquid. Further, the remaining liquid is completely blown into the target container by using inert gas, which is also beneficial to improve the precision of the liquid transfer amount.
[0045] It can be understood that, in the related art, the liquid remains in the syringe due to the influence of the extraction and discharge pipelines, which not only seriously corrodes the high-precision syringe pump, but also affects the liquid transfer precision. In order to further improve the precision of the liquid transfer amount of the liquid transfer device, based on the above-mentioned embodiment, the present application also provides another embodiment, which is described below with reference to Figure 2 , which can include the following content:
[0046] The liquid transfer device can further include a liquid level sensor 6 and a buffer container 7. Correspondingly, the connecting pipeline 4 of the above-mentioned embodiment is two sections, i.e., the connecting pipeline 4 can include a first connecting pipeline 41 and a second connecting pipeline 42; the buffer container 7 is arranged between the first connecting pipeline 41 and the second connecting pipeline 42; and the liquid level sensor 6 is arranged between the buffer container 7 and the multi-channel switching valve 2.
[0047] In the present embodiment, after the buffer container 7 is added to the liquid transfer device, the connection relationship of the entire device is as follows: one end of the first connecting pipeline 41 is connected to the syringe 3 and the inert gas discharge assembly 5 respectively, and the other end is connected to one end of the buffer container 7; one end of the second connecting pipeline 42 is connected to the other end of the buffer container 7, and the other end is connected to the common port 21 of the multi-channel switching valve 2.
[0048] The liquid level sensor 6 is used to measure the liquid level in the second connecting pipeline 42, and any sensor capable of detecting the liquid level can be used, and the present application does not make any limitation. The buffer container 7 is used to temporarily store the liquid drawn from the source container 11. Specifically, the second connecting pipeline 42 and the buffer container 7 of the present embodiment both temporarily store the liquid to be transferred. During the liquid drawing process, the switcher 23 of the multi-channel switching valve 2 is switched to the interface corresponding to the source container 11, and the piston 31 of the syringe 3 is pulled down to form a negative pressure to draw the liquid in the source container 11 into the second connecting pipeline 42. The liquid level in the second connecting pipeline 42 is detected by the liquid level sensor 6. When the liquid level reaches the specified position of the second connecting pipeline 42, i.e., the target position of the present embodiment, the drawing action of the syringe 3 is paused, and the current position of the piston 31 in the syringe 3 is read. According to the corresponding relationship between the movement distance of the piston 31 of the syringe 3 and the drawn liquid, the movement distance of the piston 31 is determined based on the amount of the current liquid to be transferred. Based on the current position of the piston 31 and the required movement distance, the piston 31 is moved to the corresponding target position. The amount of the liquid drawn from the current position of the piston 31 to the target position is drawn into the buffer container 7. The buffer container 7 can be a buffer bottle, and the material of the buffer container 7 is not limited to glass, but can also use other corrosion-resistant materials such as PTFE (Polytetrafluoroethylene), PP (Polypropylene), stainless steel, and other materials resistant to specific reagents.
[0049] As can be seen from the above, by adding a buffer container between the multi-channel switching valve and the syringe, the liquid is temporarily stored in the buffer container, which can further avoid direct contact with the syringe to corrode the equipment, and can also shorten the length of the connecting pipeline and reduce the volume of the entire device, which is more practical. With the help of the liquid level sensor, the time when the liquid enters the buffer container is detected, and the phenomenon of insufficient liquid drawing caused by the length of the connecting pipeline does not occur, which solves the problem of precision error of the liquid transfer amount caused by the length of the connecting pipeline between the source container and the equipment, and further improves the precision of the liquid transfer amount.
[0050] As an embodiment of the above embodiment, in order to facilitate operation, facilitate installation, and reduce the requirements of the operator, the target position can be determined in advance based on the actual scene, and the liquid level sensor 6 is directly installed at the target position of the second connecting pipeline. The operator can only pause the operation of the syringe 3 when the liquid level reaches the liquid level sensor 6.
[0051] As another embodiment of the above embodiment, in order to further improve the precision of the liquid transfer amount, the liquid level sensor 6 is installed as close to the switching valve 2 as possible. In order to better control the on-off of the inert gas and realize on-demand delivery of the inert gas, the inert gas discharge assembly 5 of the present embodiment can include a gas on-off switch 51 and an inert gas source 52, such as Figure 4As shown, the inert gas source 52 is used to output inert gas; the inert gas source 52 of the embodiment has a pressure regulating function, that is, the inert gas source 52 is pressure-adjustable, and the pressure of the output gas can be adjusted in real time or at a fixed time according to the current gas pressure demand. One end of the gas on-off switch 51 is connected with the inert gas source 52, and the other end is connected with one end of the connecting pipeline 4, for controlling whether the inert gas is delivered into the connecting pipeline 4. In order to improve the practicability and flexibility, the gas on-off switch 51 can be an electromagnetic valve, and for the sake of distinction, it is referred to as a first electromagnetic valve. The gas on-off switch 51 can also be a manual switch valve. In other words, the method for controlling the inert gas of the embodiment is not limited to using an electromagnetic valve, and any method capable of controlling the on-off of the gas can be used, such as a manual switch valve.
[0052] Further, in the prior art, the high-precision syringe pump needs to extract liquid through the vacuum negative pressure of the syringe in actual use. However, the water-oxygen-sensitive reagent is usually stored in a sealed bottle. As the liquid is continuously extracted, a new dynamic pressure balance point is formed between the negative pressure in the bottle and the negative pressure of the syringe. The balance point dynamically changes and is difficult to calculate, resulting in a large error between the extracted liquid quantity and the target quantity, and greatly reducing the precision of the liquid transfer of the syringe pump. In order to solve the drawbacks of the prior art, based on the above embodiment, please refer to Figure 3 , the liquid transfer device can further include a pressure maintaining pipeline 8, one end of the pressure maintaining pipeline 8 is connected to the inert gas discharge assembly 5, and the other end is connected to the source containing container 11. A pressure regulating valve 9 and a gas on-off switch 81 can be further connected in the middle, for separately adjusting the gas pressure in the pressure maintaining pipeline and the on-off of the gas. After the system increases the pressure maintaining pipeline 8, the inert gas can pass through the connecting pipeline 4 or the pressure maintaining pipeline 8. In order to generate negative pressure to extract liquid, the inert gas discharge assembly 5 includes an inert gas source 52 and a gas on-off switch 51. The gas on-off switch 51 is used to control whether the inert gas enters the connecting pipeline 4. Correspondingly, one end of the pressure maintaining pipeline 8 is connected to the inert gas source 52. The pressure maintaining pipeline 8 is used to deliver the inert gas into the source containing container 11, so as to maintain the positive pressure in the source containing container. During the liquid extraction process, the negative pressure will not be formed due to the reduction of the liquid, and the precision of the liquid transfer quantity is affected due to the generation of the negative pressure in the source containing container.
[0053] The embodiment introduces the inert gas into the sealed source containing container 11 through the pressure maintaining pipeline, avoids the formation of negative pressure in the source containing container during the liquid extraction process, affects the liquid suction quantity, and further improves the precision of the liquid transfer quantity.
[0054] Further, as shown in Figure 4As shown, in order to prevent mutual contamination between reagents, the branch of the pressure maintaining pipeline 8 of the above embodiment can also be added with a gas on-off switch such as an electromagnetic valve, the number of gas on-off switches is the same as the number of source containers, and each gas on-off switch is used to control the gas path of the corresponding source container. For example Figure 4 As shown, the source container includes two, and the corresponding gas on-off switch is also provided with two, that is, the gas on-off switch 82 controls the source container 13, and the gas on-off switch 81 controls the source container 11.
[0055] In order to make the skilled in the art more clearly understand the technical solutions of the present application, the present application also gives an illustrative embodiment, please refer to Figure 4 In the present embodiment, the multi-channel switching valve 2 can adopt a three-channel switching valve, which includes three interfaces, in order to facilitate description, the three interfaces are respectively called the first interface 221, the second interface 222, and the third interface 223. The present embodiment is to use the syringe 3 to transfer the liquid of the source container 11 and the source container 13 to the target container 12, the source container 11 and the source container 13 can be sealed reagent bottles, the target container 12 can be a reaction flask, the gas on-off switch 51, the gas on-off switch 81, and the gas on-off switch 82 can adopt electromagnetic valves, and the buffer container 7 can adopt a buffer bottle, the present embodiment can include the following contents:
[0056] The liquid transfer device may include a sealed source container 11, a sealed source container 13, a target container 12, a multi-channel switching valve 2, a syringe 3, connecting pipes between the parts, namely a first connecting pipe 41 and a second connecting pipe 42, a liquid level sensor 6, a buffer container 7, a gas on / off switch 51, an inert gas source 52, a pressure holding pipe 8, a pressure regulating valve 9, a first branch gas path 801 connecting the pressure holding pipe 8 to the source container 11 to input inert gas, a second branch gas path 802 connecting the pressure holding pipe 8 to the source container 13 to input inert gas, a gas on / off switch 81 controlling the first branch gas path 801, and a gas on / off switch 82 controlling the second branch gas path 802. The multi-channel switching valve 2 can switch between the common port 21 and different interfaces via a switcher 23. For example, to extract reagents from the source container 11, the switcher 23 can be rotated to interface 221 to connect the common port 21 to interface 211. The multi-channel switching valve 2 is connected to the lower end of the buffer container 7 via a second connecting pipe 42 for temporary storage of the aspirated reagent liquid. A liquid level sensor 6 is installed between the multi-channel switching valve 2 and the buffer container 7 to detect the liquid level in the second connecting pipe 42, thereby improving the accuracy of liquid aspiration. The upper end of the buffer container 7 is connected to the syringe 3 and the outlet of the gas on / off switch 51. The inlet of the gas on / off switch 51 is connected to the inert gas source 52, and the gas on / off switch 51 controls the flow of inert gas. The pressure regulating valve 9 is used to adjust the gas pressure in the pressure holding pipe 8, which maintains the gas pressure in the source container 11 and source container 13. When drawing liquid from the sealed bottle, the gas on / off switches 81 and 82 are opened, and inert gas is continuously introduced into the source container 11 and source container 13 to maintain a certain positive pressure. During the liquid extraction process, negative pressure will not be formed due to the decrease of liquid, thus avoiding the impact of negative pressure on the accuracy of liquid transfer.
[0057] During liquid aspiration, the switch 23 of the multi-channel switching valve 2 is turned to interface 221, controlling the piston 31 of the syringe 3 to move downwards, creating negative pressure to draw liquid from the source container 11. When the liquid reaches the level sensor 6, the operation of the syringe 3 is paused, the current position of the piston 31 is read, and then the piston 31 is moved quantitatively to draw a quantitative amount of reagent into the buffer container 7. The level sensor avoids the accuracy error in liquid transfer caused by the length of the connecting tubing between the reagent bottle and the equipment; furthermore, the transferred liquid does not directly contact the syringe, preventing corrosion of the syringe.
[0058] When the liquid suction is completed, the switcher 23 is switched to the interface 222, the pipeline is connected to the target container 12, the piston 31 is moved to the highest point, the liquid is discharged into the target container 12, the gas on-off switch 51 is opened, the inert gas is introduced, the buffer container 7 and the liquid in the pipeline are completely discharged into the target container 12, the liquid residue in the buffer container 7 and the pipeline is avoided, the liquid transfer error is reduced, and the corrosion problem of the liquid residue is solved.
[0059] As can be seen from the above, the inert gas is continuously introduced into the closed reagent bottle, the air pressure in the reagent bottle is maintained, and the precision of the liquid transfer amount is improved; secondly, the liquid level sensor is added after the multi-channel switch valve, the precision error of the liquid transfer amount caused by the length of the connecting pipeline is avoided; finally, the buffer bottle and the inert gas passage controlled by the electromagnetic valve are added between the multi-channel switch valve and the syringe, the corrosion of the strong corrosive liquid to the device itself is avoided, the residual liquid is completely blown into the reaction bottle, and the precision of the liquid transfer amount is improved.
[0060] The liquid transfer device provided in the application is described in detail. The embodiments in the specification are described in a progressive manner, and each embodiment mainly describes the difference from other embodiments. The same and similar parts of each embodiment can be referred to each other. It should be pointed out that the ordinary skilled in the art can make some improvements and modifications without departing from the principle of the application, and these improvements and modifications also fall within the protection scope of the claims of the application.
Claims
1. A liquid transfer device, characterized in that, Includes a multi-channel switching valve, syringe, connecting tubing, inert gas venting assembly, buffer container, level sensor, and pressure holding tubing; The multi-channel switching valve includes a common port, multiple interfaces, and a switcher; the connecting pipeline temporarily stores water-oxygen sensitive and highly corrosive solutions to be transferred, and its length is determined according to the capacity of the water-oxygen sensitive and highly corrosive solutions to be transferred and to prevent them from entering the syringe. The syringe and the inert gas emission assembly are connected to the common port at one end of the multi-channel switching valve through the connecting pipe. The other end of the multi-channel switching valve is connected to the source container and the target container through various interfaces. The syringe and the inert gas emission assembly are connected to the source container and the target container through the connecting pipe, the common port, the switch and the corresponding interfaces. The connecting pipeline includes a first connecting pipeline and a second connecting pipeline; the buffer container is disposed between the first connecting pipeline and the second connecting pipeline; one end of the first connecting pipeline is connected to the syringe and the inert gas emission assembly, and the other end is connected to one end of the buffer container; one end of the second connecting pipeline is connected to the other end of the buffer container, and the other end is connected to the common port; the liquid level sensor, used to measure the liquid level in the second connecting pipeline, is disposed between the buffer container and the multi-channel switching valve; the buffer container is used to temporarily store the liquid drawn from the source container; The inert gas emission assembly delivers inert gas to the outside through the connecting pipeline; the syringe transfers the water-oxygen-sensitive and highly corrosive solution to be transferred from the source container to the target container through the connecting pipeline and the multi-channel switching valve. One end of the pressure-holding pipeline is connected to the inert gas emission assembly, and the other end is connected to the source container; the pressure-holding pipeline is used to deliver inert gas to the source container to maintain the positive pressure inside the source container.
2. The liquid transfer device according to claim 1, characterized in that, The liquid level sensor is installed at the target location in the second connecting pipeline.
3. The liquid transfer device according to claim 1, characterized in that, The number of interfaces of the multi-channel switching valve is equal to the sum of the number of source containers and the number of target containers.
4. The liquid transfer device according to claim 1, characterized in that, The inert gas emission assembly includes a gas on / off switch and an inert gas source with pressure regulation function; The inert gas source is used to output inert gas, and the pressure of the output gas is adjusted according to the current gas pressure requirement; One end of the gas on / off switch is connected to the inert gas source, and the other end is connected to one end of the connecting pipeline, used to control whether the inert gas is delivered to the connecting pipeline.
5. The liquid transfer device according to claim 4, characterized in that, The gas on / off switch is the first solenoid valve.
6. The liquid transfer device according to claim 4, characterized in that, The gas on / off switch is a manually operated valve.
7. The liquid transfer device according to claim 1, characterized in that, A pressure regulating valve is also provided between the pressure holding short circuit and the inert gas emission component; the pressure regulating valve is used to control the gas pressure of the pressure holding pipeline independently; the pressure holding pipeline is also provided with a gas on / off switch with the same number as the source container.
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