A device for holding liquids during a multichannel pipetting operation
By designing a multi-gun device with an ultraviolet lamp, efficient disinfection and contamination prevention of solution transfer were achieved, solving the problems of low operational efficiency and contamination risk in existing technologies, and improving experimental efficiency and success rate.
Patent Information
- Application Number
- CN202311049016.7
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2023-08-21
- Publication Date
- 2025-11-07
- Estimated Expiration
- 2043-08-21
AI Technical Summary
Existing multi-channel pipette devices require frequent cleaning and sterilization during solution transfer, resulting in low operational efficiency. Furthermore, failure to sterilize in a timely manner may lead to sample contamination and affect experimental results.
A device comprising a shell, a liquid tank, an ultraviolet lamp, and a liquid membrane was designed. The liquid membrane and the device are sterilized by the ultraviolet lamp. The inverted triangular prism-shaped liquid tank and the serrated open window are used to ensure solution transfer efficiency and prevent contamination.
It improves solution transfer efficiency, reduces the risk of experimental sample contamination, simplifies consumable handling, and increases experimental operation efficiency and success rate.
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Figure CN117205981B_ABST
Abstract
Description
TECHNICAL FIELD
[0001] The present application belongs to the technical field of liquid containing device for row gun liquid transfer, and particularly relates to a device for containing liquid during row gun liquid transfer. BACKGROUND
[0002] In the process of molecular biology experiment, especially in the process of PCR experiment, due to the necessity of repeating the biology experiment, the detection personnel need to mix buffer, enzyme and other solutions in the centrifugal tube first, and then transfer the mixed solution into 8-row or 96-hole plate for machine operation. In the process of transferring the solution, the experiment personnel will use a continuous liquid dispenser or a row gun for operation, and the row gun is favored due to its high operation efficiency and convenience.
[0003] Since the mixed solution is in the centrifugal tube with small diameter, and the row gun is equipped with multiple elastic suction nozzles, it is impossible to connect all the suction nozzles with the suction head (gun head) at one time and extend into the centrifugal tube to suck the liquid. Therefore, the experiment personnel usually use a cuboid plastic groove, sterilize it at high temperature, pour the mixed solution into the groove, and then use the row gun to suck and transfer the solution. However, this simple device has some defects, such as: the liquid transfer device needs to be cleaned and sterilized before each use, and the operation efficiency is low. If the device is not sterilized in time, the experimental sample may be contaminated, the experimental result may be affected, and the experiment may fail. SUMMARY
[0004] Therefore, the present application provides a device for containing liquid during row gun liquid transfer, which can improve the solution transfer efficiency, reduce the experimental sample pollution, and improve the experimental operation efficiency.
[0005] To achieve the above-mentioned purpose, the technical scheme of the present application is as follows:
[0006] A device for containing liquid during row gun liquid transfer, comprising a shell, a liquid containing groove; the liquid containing groove is located on one side in the shell, and an ultraviolet lamp, a cross rod and a liquid containing film are further arranged in the shell; the ultraviolet lamp is fixed on the side wall on the other side in the shell; the liquid containing film is rolled into a drum shape and is sleeved on the cross rod; one end of the cross rod is connected with the shell; a power adapter and a switch are arranged on the outer side of the shell; the power adapter is connected with an external power supply and the ultraviolet lamp; the switch is connected with the power adapter; the liquid containing groove is in the shape of an inverted triangular prism; connecting windows are arranged on both sides of the liquid containing groove; an open window is arranged on the side of the shell close to the liquid containing groove; the liquid containing film is attached to the liquid containing groove through the connecting windows; a door is arranged on the shell and located in front of the cross rod.
[0007] Further, an LED lamp is arranged in the shell and connected with the power adapter.
[0008] Further, the material of the shell, the liquid loading groove and the crossbar is polypropylene material, and the material of the liquid loading film is PE film.
[0009] Further, the lower end of the open window is sawtooth-shaped, the liquid loading film is pulled out from the open window and cut downward.
[0010] Further, the open window is consistent in height with the connecting window.
[0011] Further, the sliding rail is used between the door and the shell.
[0012] The present application has the following advantages:
[0013] 1) The ultraviolet lamp is used to disinfect and sterilize the liquid loading film and the whole device, so that the risk of solution pollution during the experiment is reduced, and the success rate of the experiment is improved.
[0014] 2) The experimental solution is placed on the liquid loading film, so that the solution cannot leak into the liquid loading groove to form pollution, the used liquid loading film is cut through the sawtooth of the open window after each use, the unused liquid loading film is recycled, the consumables are conveniently handled, the utilization rate of consumables is improved, and the operation is simple, which is beneficial to improve the experimental efficiency.
[0015] 3) The liquid loading groove is set as an inverted triangular prism, which is beneficial to the attachment of the liquid loading film and the gathering of the mixed solution during use, facilitates the transfer of liquid, and improves the pipetting efficiency. BRIEF DESCRIPTION OF DRAWINGS
[0016] Figure 1 It is a structure schematic view of the device for containing liquid when the row gun pipetting is carried out according to the embodiment of the present application.
[0017] Figure 2 It is a left view of the device for containing liquid when the row gun pipetting is carried out according to the embodiment of the present application.
[0018] Figure 3 It is a right view of the device for containing liquid when the row gun pipetting is carried out according to the embodiment of the present application.
[0019] Figure 4 It is a top view of the device for containing liquid when the row gun pipetting is carried out according to the embodiment of the present application.
[0020] Figure 5 It is a front view of the device for containing liquid when the row gun pipetting is carried out according to the embodiment of the present application.
[0021] 1 is an ultraviolet lamp, 2 is a crossbar, 3 is a liquid loading film, 4 is a connecting window, 5 is a shell, 6 is an open window, 7 is a switch, 8 is a power adapter, 9 is a liquid loading groove, 10 is a sawtooth, and 11 is a door. DETAILED DESCRIPTION
[0022] To provide a more detailed understanding of the features and technical content of this invention, the implementation of this invention will be described in detail below with reference to the accompanying drawings. The accompanying drawings are for reference only and are not intended to limit this invention.
[0023] like Figures 1-5 As shown, the liquid-holding device for pipetting in this embodiment of the invention includes a housing 5 and a liquid-holding tank 9. The liquid-holding tank 9 is located inside one side of the housing 5. The other side of the housing 5 is provided with an ultraviolet lamp 1, a crossbar 2, and a liquid-holding membrane 3. The ultraviolet lamp 1 is fixed to the side wall of the other side of the housing 5. The liquid-holding membrane 3 is rolled into a roller shape and fitted onto the crossbar 2. One end of the crossbar 2 is connected to the housing 5. The outer side of the housing 5 is provided with a power adapter 8 and a switch 7. The power adapter 8 connects to an external power source and the ultraviolet lamp 1. The switch 7 is connected to the power adapter 8 and controls the ultraviolet lamp 1. The ultraviolet lamp 1 is used to disinfect and sterilize the entire pipetting device, especially the liquid-holding membrane 3. The liquid-holding tank 9 is an inverted triangular prism shape, which is beneficial for use. The liquid film 3 adheres to the liquid tank 9 and allows the mixed MIX solution to converge. The liquid tank 9 has connecting windows 4 on both sides, and the housing 5 has an open window 6 on the side near the liquid tank 9. The connecting windows 4 and the open window 6 are at the same height. The lower end of the open window 6 has serrations 10. During use, the liquid film 3 passes through the connecting window 4, and the liquid film 3 is pressed onto the liquid tank 9 by the nozzle used in the experiment. After use, the liquid film 3 is pulled out from the open window 6 and cut using the serrations 10. The housing 5 has a door 11, which can be connected to the housing 5 by a slide rail. The door 11 is located in front of the crossbar 2. Opening the door 5 allows operation of the liquid film 3.
[0024] The shell 5, liquid tank 9 and crossbar 2 are made of polypropylene, and the liquid membrane 3 is made of PE film.
[0025] In routine experiments, the amount of solution used is small, and the solution will not overflow the liquid membrane 3.
[0026] The specific usage process of a device for holding liquid during pipetting according to an embodiment of the present invention is as follows:
[0027] Before using the device, the experimenter wears new latex gloves and operates on the ultraviolet clean bench, slides the warehouse door on the front of the device upward, puts the liquid loading film rolled into a drum on the horizontal rod on the inner side wall of the film loading warehouse, slides the warehouse door downward again, connects the power adapter, turns on the power, opens the switch of the ultraviolet lamp on the outside of the liquid loading device, disinfects and sterilizes the device, especially the liquid loading film to be used. After 15 minutes, turn off the switch of the ultraviolet lamp, slide the warehouse door upward, pull out the liquid loading film to pass through the connecting window of the liquid loading tank, then pass through the open window on the other side of the liquid loading tank, press the liquid loading film downward with the gun head used in the experiment to make it adhere to the liquid loading tank, then add the MIX solution mixed in advance, use the gun to transfer the solution on the film in the liquid loading tank to improve the solution transfer efficiency. After completing the liquid transfer, pull out the used liquid loading film from the open window, and use the sawtooth at the lower end of the open window to cut the used film section for easy waste disposal. After use, use the drum to recover the film exposed in the liquid loading tank to the drum-shaped liquid loading film, slide the warehouse door downward, turn on the ultraviolet lamp switch, and disinfect and sterilize the entire device and the liquid loading film.
[0028] The specific models of the above-mentioned devices are not limited and described in detail, and the deep connection mode of the above-mentioned devices is not described in detail, which is well known to those skilled in the art.
[0029] The above only describes the preferred embodiments of the present application, and is not used to limit the protection scope of the present application. Any modifications, equivalent replacements and improvements made within the spirit and principles of the present application shall be included in the protection scope of the present application.
Claims
1. A device for holding liquid during a gang pipetting operation, characterized in that Including shell, liquid tank; The liquid tank is located in the shell one side, the shell still is equipped with ultraviolet lamp, cross rod, liquid loading film, the ultraviolet lamp is fixed on the other side wall in the shell, the liquid loading film is rolled into the drum shape, is equipped with in the cross rod, one end of the cross rod is connected with the shell, the outside surface of the shell is equipped with power adapter and switch, the power adapter is connected with the ultraviolet lamp outside power supply, the switch is connected with the power adapter;The liquid tank is inverted triangular prism, both sides of the liquid tank are equipped with connecting window, the side of the shell close to the liquid tank is equipped with open window, the liquid loading film passes through the connecting window and is attached to the liquid tank, the shell is equipped with warehouse door, the warehouse door is located in the front of the cross rod.
2. A device for holding liquid during pipetting by a row of pipettes according to claim 1, characterized in that The shell is equipped with LED lamp, and the LED lamp is connected with the power adapter.
3. The device of claim 1, wherein the device is a liquid reservoir for use in a liquid handling gun. The material of the shell, liquid tank and cross rod is polypropylene material, and the material of the liquid loading film is PE film.
4. The device of claim 1, wherein the device is a liquid reservoir for use in a liquid handling gun. The lower end of the open window is sawtooth, the liquid loading film is pulled out from the open window and cut downward.
5. The device of claim 1, wherein the device is a liquid reservoir for use in a liquid handling gun. The open window and the connecting window are consistent in height.
6. The device of claim 1, wherein, The warehouse door and the shell adopt slide rail up and down sliding.
Citation Information
Patent Citations
Freeze-drying preparation based on quantitative pipetting device
CN114367322A
Suction device
CN1292729A