Anti-hair loss composition and preparation method and application thereof

Abstract

The present invention provides an anti-hair loss composition and a preparation method and application thereof, belonging to the technical field of daily cosmetics. The anti-hair loss composition includes the following components by weight percentage: 12-20% plant extract; 0.3-1.0% moisturizer; 0.05-0.3% penetrant; 0.3-0.8% conditioner; 0.5-1.0% preservative, 0.02-0.05% colorant and water balance. The anti-hair loss composition provided by the present invention significantly improves the interaction between the components by adjusting the types and addition amounts of each component, and a mixture of grape seed extract, Polygonum multiflorum root extract, Ganoderma lucidum root extract, Saw palmetto extract, Equisetum arvense leaf extract and Ligusticum chuanxiong extract as a plant extract can nourish hair follicles, enhance hair toughness, and improve the anti-hair loss effect while nourishing hair.

Description

Technical Field

[0001] The invention belongs to the technical field of daily cosmetics, and particularly relates to an anti-hair loss composition and a preparation method and application thereof. Background Art

[0002] With the accelerated pace of life, modern young people have become more and more serious about hair loss due to irregular diet and work and rest, huge life pressure and other reasons, causing many people to have sparse hair or even baldness at a young age. In mild cases, it affects personal appearance, and in severe cases, it causes personal psychological trauma. Studies have found that hair loss is mainly caused by the following reasons: First, the deterioration of the human body's scalp ecology leads to a disorder of the scalp environment, causing loose or blocked hair follicles; second, metabolic disorders in the body stimulate the sebaceous glands to secrete vigorously, resulting in a large amount of oil pressing on the roots of the hair, which blocks the blood and nutrition supply required by the hair, resulting in seborrheic alopecia; third, the lack of trace elements leads to malnutrition of hair follicles and difficulty in hair growth.

[0003] Hair loss can be divided into seborrheic alopecia and alopecia areata according to the mechanism of etiology. Seborrheic alopecia (SA), also known as male pattern baldness (MPA) and androgenic alopecia (AGA), is a progressive hair loss on the head, also known as male pattern baldness and androgenic alopecia. It is a common and frequently occurring disease in dermatology and one of the intractable diseases. Studies have shown that abnormal androgen levels are the main pathogenesis of seborrheic alopecia: testosterone in hair follicle cells is converted into dihydrotestosterone (DHT) by 5-reductase (5-AR), which causes hair follicle cells to enter the resting phase through a series of cellular biochemical reactions, thereby causing terminal hair to transform into vellus hair, ultimately leading to hair loss.

[0004] At present, there are a wide variety of anti-hair loss shampoos on the market, and the effects vary. Traditional anti-hair loss shampoos achieve the anti-hair loss effect by adding chemical substances. However, such shampoos are very likely to irritate the hair or skin, causing allergies, and therefore are difficult to meet the needs of the general public. In recent years, some anti-hair loss shampoos with plant extracts as the main ingredient have appeared. However, due to the short contact time between shampoo and the scalp during use, the active ingredients in the plant extracts are difficult to fully exert their effects in a short period of time, resulting in insignificant anti-hair loss effects, especially for preventing seborrheic alopecia.

[0005] Chinese patent CN114224797A discloses an anti-hair loss essence and a preparation method thereof, a Chinese herbal composition and a preparation method thereof, comprising the following components by weight: 3-5 parts of angelica extract, 0.08-0.16 parts of Linderae sibiricum extract, 3-5 parts of saffron extract, 3-5 parts of black ganoderma extract, 3-5 parts of ginseng extract, 0.2-0.4 parts of nasturtium extract, 3-5 parts of Polygonum multiflorum extract, 3-5 parts of Chuanxiong extract, and 1-2 parts of pea extract. The anti-hair loss Chinese herbal composition can improve the activity of tyrosinase and increase melanin synthesis, effectively promote the proliferation of hair follicle cells, and achieve the effect of tightening hair and making white hair black, but the anti-hair loss effect of the composition is not significant.

[0006] Chinese patent CN103446563B discloses a Chinese herbal medicine composition for preventing hair loss that inhibits the activity of 5α-reductase, which is composed of the following components: saw palmetto extract, bayberry peel extract, arborvitae extract, angelica extract, rhizoma anemarrhenae extract, herba prunellae extract, ginger extract, sophora flavescens extract, japanese jackfruit extract, schisandra chinensis fruit extract, kaempferia galanga extract. The Chinese herbal medicine compound for hair loss can be used to treat symptoms of seborrheic alopecia caused by male androgen. However, the Chinese herbal medicine composition contains a variety of Chinese medicinal ingredients that are prone to allergic reactions, and the moisturizing effect on the scalp and hair follicles is not ideal.

[0007] Therefore, it is necessary to develop a composition and a preparation method thereof that can effectively prevent hair loss, and can effectively moisturize hair follicles and enhance hair toughness. Summary of the invention

[0008] Based on the deficiencies in the prior art, the present invention aims to provide an anti-hair loss composition and a preparation method and application thereof.

[0009] In order to achieve the above object, the present invention adopts the following technical solution:

[0010] An anti-hair loss composition comprises the following components by weight percentage: 12-20% of plant extract, 0.3-1.0% of moisturizing agent, 0.05-0.3% of penetrant, 0.3-0.8% of conditioning agent, 0.5-1.0% of preservative, 0.02-0.05% of colorant and the balance of water.

[0011] Preferably, the anti-hair loss composition comprises the following components by weight percentage: 15-18% plant extract; 0.3-0.6% moisturizer; 0.1-0.2% penetrant; 0.4-0.6% conditioner; 0.6-0.8% preservative, 0.03-0.05% colorant and the balance water.

[0012] The plant extract is selected from one or more of grape seed extract, polygonum multiflorum root extract, ginger extract, ganoderma lucidum root extract, sophora flavescens root extract, angelica root extract, saw palmetto extract, equisetum arvense leaf extract, chuanxiong extract and orientalis extract;

[0013] Preferably, the plant extract is selected from one or more of grape seed extract, Polygonum multiflorum root extract, Ganoderma lucidum root extract, Angelica sinensis root extract, Saw palmetto extract, Equisetum arvense leaf extract, Ligusticum chuanxiong extract and Platycladus orientalis extract.

[0014] More preferably, the plant extract is a mixture of grape seed extract, Polygonum multiflorum root extract, Ganoderma lucidum root extract, Serenoa repens extract, Equisetum arvense leaf extract and Ligusticum chuanxiong extract.

[0015] Further preferably, the plant extracts are grape seed extract, Polygonum multiflorum root extract, Ganoderma lucidum root extract, Saw palmetto extract, Equisetum arvense leaf extract and Ligusticum chuanxiong extract in a mass ratio of 1:3-5:2-3:1-3:1-3:2-5.

[0016] More preferably, the plant extracts are grape seed extract, Polygonum multiflorum root extract, Ganoderma lucidum root extract, Saw palmetto extract, Equisetum arvense leaf extract and Ligusticum chuanxiong extract in a mass ratio of 1:4:2:2:1:5.

[0017] During the implementation of the present invention, it was unexpectedly found that a mixture of grape seed extract, Polygonum multiflorum root extract, Ganoderma lucidum root extract, Saw palmetto extract, Equisetum arvense leaf extract and Ligusticum chuanxiong extract as a plant extract can nourish hair follicles and enhance hair toughness.

[0018] The moisturizing agent is selected from one or more of butylene glycol, glycerin and hyaluronic acid;

[0019] Preferably, the moisturizing agent is a mixture of butylene glycol and glycerol, and the mass ratio of the two is 3:1.

[0020] The penetrant is selected from one or more of tanshinone, tetrahydropiperine, inositol and laurocapram;

[0021] Preferably, the penetrant is a mixture of tanshinone, tetrahydropiperine and inositol;

[0022] More preferably, the mass ratio of tanshinone, tetrahydropiperine and inositol is 2-3:2:1; further preferably, the mass ratio of tanshinone, tetrahydropiperine and inositol is 3:2:1.

[0023] The conditioning agent is a mixture of hydrolyzed glycosaminoglycan and betaine. Preferably, the mass ratio of the hydrolyzed glycosaminoglycan to betaine is 1:1.

[0024] During the implementation of the present invention, it was unexpectedly found that controlling the mass ratio of the penetrant and the conditioner can significantly improve the nourishing effect of the composition, effectively adjust the water-oil balance of the scalp, activate the scalp, help the scalp restore normal metabolism, and form a protective barrier.

[0025] Preferably, the mass ratio of the penetrant to the conditioner is 1:2-6; more preferably, the mass ratio of the penetrant to the conditioner is 1:2-4; further preferably, the mass ratio of the penetrant to the conditioner is 1:2-3.

[0026] The preservative is a mixture of ethylhexylglycerin and p-hydroxyacetophenone, and the mass ratio of the two is 1:4.

[0027] The colorant is a conventional colorant in the art.

[0028] As a preferred embodiment, the anti-hair loss composition comprises the following components by weight percentage:

[0029] Plant extract 18%; moisturizer 0.5%; penetrant 0.18%; conditioner 0.5%; preservative 0.6%, colorant 0.04% and water balance;

[0030] The plant extracts are grape seed extract, Polygonum multiflorum root extract, Ganoderma lucidum root extract, Saw palmetto extract, Equisetum arvense leaf extract and Ligusticum chuanxiong extract in a mass ratio of 1:4:2:2:1:5;

[0031] The moisturizing agent is butylene glycol and glycerin in a mass ratio of 3:1;

[0032] The penetrant is tanshinone, tetrahydropiperine and inositol in a mass ratio of 3:2:1;

[0033] The conditioning agent is hydrolyzed glucosaminoglycan and betaine in a mass ratio of 1:1.

[0034] The preservatives are ethylhexylglycerin and p-hydroxyacetophenone in a mass ratio of 1:4.

[0035] The present invention also provides a method for preparing the above anti-hair loss composition, comprising the following steps:

[0036] (1) Weigh the amount of conditioning agent and water in the formula into a stirring pot, soak for 30 minutes, then add the penetrant and stir slowly to raise the temperature to 85°C. After keeping the temperature and stirring for 30 minutes, add the preservative, moisturizer and plant extract and continue to keep the temperature and stir for 30 minutes. After all components are dissolved evenly, start to cool down;

[0037] (2) When the temperature drops to 45° C., add the colorant and stir evenly, then continue to cool to room temperature to obtain the anti-hair loss composition.

[0038] The present invention also provides application of the anti-hair loss composition in preparing hair care products.

[0039] The hair care products include but are not limited to shampoo, scalp care lotion, conditioner and hair treatment cream.

[0040] Compared with the prior art, the present invention has the following beneficial effects:

[0041] (1) The anti-hair loss composition provided by the present invention significantly improves the interaction between the components by adjusting the types and addition amounts of the components. The mixture of grape seed extract, Polygonum multiflorum root extract, Ganoderma lucidum root extract, Saw palmetto extract, Equisetum arvense leaf extract and Ligusticum chuanxiong extract as the plant extract can nourish the hair follicles, enhance the toughness of the hair, and improve the anti-hair loss effect while nourishing the hair.

[0042] (2) The present invention uses a mixture of hydrolyzed glucosaminoglycans and betaine as a conditioning agent, and a mixture of tanshinone, tetrahydropiperine and inositol as a penetrant. During the implementation process, it was unexpectedly found that controlling the mass ratio of the penetrant and the conditioning agent can significantly improve the nourishing effect of the composition, effectively regulate the water and oil balance of the scalp, activate the scalp, help the scalp restore normal metabolism, and form a protective barrier.

[0043] (3) The present invention can improve the absorption of the active ingredients in the plant extracts by hair by reasonably controlling the types of the plant extracts used in combination with the conditioners and penetrants, thereby improving the antibacterial effect. DETAILED DESCRIPTION

[0044] The above features mentioned in the present invention or the features mentioned in the embodiments can be combined in any way. All the features explained in the specification of this case can be used in combination with any method form, and each feature disclosed in the specification can be replaced by any alternative feature that can provide the same, equal or similar purpose. Therefore, unless otherwise specified, the disclosed features are only general examples of equal or similar features.

[0045] The present invention will be further described below in conjunction with specific examples. These examples are only used to illustrate the present invention and are not intended to limit the scope of the present invention. In the following examples, the implementation methods for specifying specific conditions are usually based on conventional conditions or the conditions recommended by the manufacturer. Unless otherwise specified, all percentages and fractions are by weight.

[0046] Unless otherwise defined, all professional and scientific terms used herein have the same meanings as those known to those skilled in the art. In addition, any methods and materials similar or equivalent to those described herein can be applied to the methods of the present invention. The preferred implementation methods and materials described herein are for demonstration purposes only.

[0047] The purchase manufacturers and models of the components used in the following examples are:

[0048]

[0049] Example 1 An anti-hair loss composition and preparation method thereof

[0050] The composition includes the following components by weight percentage:

[0051]

[0052] The preparation method comprises the following steps:

[0053] (1) Weigh the amount of conditioning agent and water in the formula into a stirring pot, soak for 30 minutes, then add the penetrant and stir slowly to raise the temperature to 85°C. After keeping the temperature and stirring for 30 minutes, add the preservative, moisturizer and plant extract and continue to keep the temperature and stir for 30 minutes. After all components are dissolved evenly, start to cool down;

[0054] (2) When the temperature drops to 45° C., add the colorant and stir evenly, then continue to cool to room temperature to obtain the anti-hair loss composition.

[0055] Example 2 An anti-hair loss composition and its preparation method

[0056] The composition includes the following components by weight percentage:

[0057]

[0058] The preparation method comprises the following steps:

[0059] (1) Weigh the amount of conditioning agent and water in the formula into a stirring pot, soak for 30 minutes, then add the penetrant and stir slowly to raise the temperature to 85°C. After keeping the temperature and stirring for 30 minutes, add the preservative, moisturizer and plant extract and continue to keep the temperature and stir for 30 minutes. After all components are dissolved evenly, start to cool down;

[0060] (2) When the temperature drops to 45° C., add the colorant and stir evenly, then continue to cool to room temperature to obtain the anti-hair loss composition.

[0061] Example 3 An anti-hair loss composition and its preparation method

[0062] The composition includes the following components by weight percentage:

[0063]

[0064] The preparation method comprises the following steps:

[0065] (1) Weigh the amount of conditioning agent and water in the formula into a stirring pot, soak for 30 minutes, then add the penetrant and stir slowly to raise the temperature to 85°C. After keeping the temperature and stirring for 30 minutes, add the preservative, moisturizer and plant extract and continue to keep the temperature and stir for 30 minutes. After all components are dissolved evenly, start to cool down;

[0066] (2) When the temperature drops to 45° C., add the colorant and stir evenly, then continue to cool to room temperature to obtain the anti-hair loss composition.

[0067] Example 4 An anti-hair loss composition and its preparation method

[0068] The composition includes the following components by weight percentage:

[0069]

[0070] The preparation method comprises the following steps:

[0071] (1) Weigh the amount of conditioning agent and water in the formula into a stirring pot, soak for 30 minutes, then add the penetrant and stir slowly to raise the temperature to 85°C. After keeping the temperature and stirring for 30 minutes, add the preservative, moisturizer and plant extract and continue to keep the temperature and stir for 30 minutes. After all components are dissolved evenly, start to cool down;

[0072] (2) When the temperature drops to 45° C., add the colorant and stir evenly, then continue to cool to room temperature to obtain the anti-hair loss composition.

[0073] Comparative Example 1

[0074] The difference from Example 4 is that the conditioning agent is only hydrolyzed glucosaminoglycan, i.e., 0.5 parts of hydrolyzed glucosaminoglycan, and the other components and contents are the same as those in Example 4.

[0075] Comparative Example 2

[0076] The difference from Example 4 is that the conditioning agent is hydrolyzed glycosaminoglycan and betaine in a mass ratio of 4:1, i.e., 0.4 parts of hydrolyzed glycosaminoglycan and 0.1 parts of betaine, and the other components and contents are the same as those in Example 4.

[0077] Comparative Example 3

[0078] The difference from Example 4 is that the penetrant is tetrahydropiperine and inositol, that is, 0.12 parts of tetrahydropiperine and 0.06 parts of inositol, and the other components and contents are the same as those in Example 4.

[0079] Comparative Example 4

[0080] The difference from Example 4 is that the mass ratio of the penetrant to the conditioner is 1:9, and the other components and contents are the same as those in Example 4.

[0081] Right now:

[0082]

[0083] Comparative Example 5

[0084] The difference from Example 4 is that the mass ratio of the penetrant to the conditioner is 9:1, and the other components and contents are the same as those in Example 4.

[0085] Right now:

[0086]

[0087] Comparative Example 6

[0088] The composition disclosed in Example 24 of prior art CN103446563B.

[0089] Comparative Example 7

[0090] Prior art: The composition disclosed in Example 6 of CN117298015A.

[0091] Effect test:

[0092] 1. Irritation test-multiple skin irritation tests

[0093] (1) Materials and methods

[0094] 1.1. Test substance: brown liquid. Use the sample as is during the experiment.

[0095] 1.2 Experimental animals and breeding environment:

[0096] Experimental animals: 4 New Zealand rabbits per group, weighing 1.8-2.2 kg, provided by Guangdong Medical Laboratory Animal Center, Laboratory Animal Production License No.: SCXK (Guangdong) 2019-0035, Quality Certificate: 44411600012783.

[0097] Breeding environment: 20-26℃, relative humidity 40-70%, experimental animal use license number: SCXK (Guangdong) 2021-0260.

[0098] Feed: Feed was provided by Guangdong Medical Experimental Animal Center, quality certificate number: 2307140062.

[0099] 1.3 Test method:

[0100] 1.3.1 Testing standard: "Technical Specification for Safety of Cosmetics" (2015 edition), Chapter 6, 4, Skin Irritation / Corrosion Test.

[0101] 1.3.2 Exposure method: Before the test, cut off the hair on both sides of the spine of the experimental animal's back, and the hair removal area is about 3cm×3cm on the left and right. Apply 0.5mL of the test substance on the left side of the animal's skin, with an application area of ​​about 2.5cm×2.5cm, once a day for 14 consecutive days, and the other side is used as a blank control. Starting from the second day, cut the hair before each application, use pure water to remove the residual test substance, and treat the control area in the same way. Observe the results after one hour.

[0102] 1.3.3 Observation operation: Observe the skin reaction under natural light and score the skin erythema and water according to the scoring standards given in Table 1 "Skin Irritation Reaction Scoring" in Chapter 6, 4 Skin Irritation / Corrosion Test of "Technical Specifications for Safety of Cosmetics" (2015 Edition) for 14 consecutive days.

[0103] 1.3.4 Result evaluation: After the test, calculate the average score of each animal per day according to the following formula, and determine the skin irritation intensity according to Table 2 "Skin Irritation Intensity Classification" in Chapter 6, 4 Skin Irritation / Corrosion Test of "Technical Specifications for Safety of Cosmetics" (2015 edition).

[0104] Average score per animal per day = / 14

[0105] (2) Test results are shown in Table 1 below.

[0106] Table 1 Results of multiple skin irritation tests on New Zealand rabbits

[0107]

[0108] According to the test results in Table 1 above, it can be seen that the anti-hair loss composition prepared by the present invention is non-irritating and can be used safely.

[0109] 2. Antibacterial performance test - inhibiting Malassezia and Propionibacterium acnes

[0110] According to Article 7.3 of QB / T2738-2012 "Evaluation Methods for Antibacterial and Antimicrobial Effects of Daily Chemical Products".

[0111] Prepare bacterial suspension: dilute the test bacterial suspension appropriately with PBS solution. The required concentration is: take 0.1 mL and drop it into 5.0 mL of control sample solution (PBS). The number of colonies recovered is 1×10 4 -9×10 4CFU / mL; According to the requirements, the composition prepared in the above embodiments and comparative examples has an action time of 5 min and a temperature of 23°C±1°C on Malassezia furfur and Propionibacterium acnes, respectively, and the test is repeated three times: the Malassezia furfur antibacterial test culture dish is placed in an incubator at 28-30°C and cultured for 72h, and the Propionibacterium acnes test culture dish is placed in an incubator at 37°C under anaerobic conditions and cultured for 72h; the negative control group is PBS and the culture medium has no bacterial growth.

[0112] The antibacterial rate is calculated according to the following formula: antibacterial rate = 100% × (average colony count of control sample - average colony count of test sample) / average colony count of control sample; and the test results (retain 1 decimal place) are recorded in Table 2.

[0113] Table 2

[0114]

[0115] According to the test data in Table 2 above, it can be seen that the compositions prepared in Examples 1-4 of the present invention have obvious antibacterial effects, among which the composition prepared in Example 4 has the best antibacterial effect and can better adjust the hair microecology. After 72 hours, the antibacterial rate of Malassezia can reach more than 90%, and the inhibition rate of Propionibacterium acnes can reach more than 80%. In Comparative Examples 1-3, changing the type of conditioner or penetrant or the mass ratio of the conditioner will affect the antibacterial effect of the composition to a certain extent. When the mass ratio of the conditioner and the penetrant is changed in Comparative Examples 4-5 and is not within the scope of protection claimed by the present invention, the antibacterial effect of the composition will be significantly affected. Comparative Examples 6 and 7 are compositions disclosed in the prior art, and their inhibitory effects on Propionibacterium acnes are obviously inferior to those of the present invention.

[0116] 3. 5α-reductase inhibition assay

[0117] (1) Test method: A control group solution and a test group solution were prepared separately and incubated; the control group solution was an enzyme reaction system, and the enzyme reaction system was incubated at 37°C for 30 min.

[0118] Test group solution: The plant extracts in Examples 1-4 and Comparative Examples 6-7 were dissolved in 50% ethanol to prepare a solution with a concentration of 1%; 0.5 mL of the solution was placed in an enzyme reaction system and incubated at 37° C. for 30 min.

[0119] (2) The formula of the enzyme reaction system is as follows: 5 mL of deionized water, 2 μL of 1 mmol / L testosterone, 600 μL of 10 mg / mL rat steroid 5α-reductase solution, and 200 μL of 1 mmol / L NADPH solution.

[0120] (3) Detection step: Use a UV-visible spectrophotometer to detect the decrease in absorbance of the control group solution and the test group solution before and after incubation at a wavelength of 340 nm. The decrease in absorbance of the control group solution is recorded as △A0, and the decrease in absorbance of the test group solution is recorded as △An (△A1-△A6).

[0121] And calculate the enzyme activity inhibition rate.

[0122] Enzyme activity inhibition rate (%) = (△A0-△An) / △A0×100%

[0123] Among them, △A0 is the absorbance decrease value of the control group solution, △An is △A1-△A6, which are the absorbance decrease values ​​of the test group solutions prepared with the plant extracts in Examples 1-4 and Comparative Examples 6-7 respectively; the enzyme activity inhibition rate is recorded in Table 3.

[0124] Table 3

[0125]

[0126] According to the test results in Table 3 above, the plant extracts in the compositions provided in Examples 1-4 of the present invention can significantly inhibit the activity of 5α-reductase, reduce the production of dihydrotestosterone, and promote the division of hair follicle cells, thereby achieving excellent anti-hair loss effects. Comparative Examples 6-7 are components disclosed in the prior art, and their effects of inhibiting 5α-reductase activity are significantly inferior to those of Examples 1-4 of the present application.

[0127] 4. Satisfaction test

[0128] 4.1 Test Articles:

[0129] (1) Test products: samples prepared in Examples 1-4 and Comparative Examples 1-5;

[0130] (2) Control product: A commercially available product with no anti-hair loss effect, tested in parallel with the test product.

[0131] 4.2 Usage instructions: Apply an appropriate amount of the sample to the scalp and massage the scalp in a spiral motion with your fingertips for 5-10 minutes until it is completely absorbed. Use once a day.

[0132] 4.3 Subjects: A total of 60 subjects, aged 22-43 years old, 10 in each group, met the voluntary inclusion criteria.

[0133] 4.4 Environmental conditions: temperature 20-22℃, relative humidity 40%RH-60%RH.

[0134] 4.5 Testing method: The test shall be carried out in accordance with the specific requirements of the "Technical Specification for Safety of Cosmetics" (2015 edition). The product shall be scored after 2 weeks of use. The highest score is 10 points and the lowest score is 0 points. The score can be a decimal. The average value of the scores given by each volunteer (keep 1 decimal place) shall be recorded in Table 4.

[0135] Table 4

[0136]

[0137] According to the test data in Table 4 above, it can be seen that the anti-hair loss composition prepared by the present invention has good dry combing properties, that is, the softness of the hair is improved after use, and the anti-hair loss effect and anti-itching effect are relatively good, that is, it can achieve the effects of anti-itching, anti-hair loss and hair solidification. In particular, the product prepared in Example 4 has better user experience and the best comprehensive score.

[0138] The above embodiments are preferred implementation modes of the present invention, but the implementation modes of the present invention are not limited to the above embodiments. Any other changes, modifications, substitutions, combinations, and simplifications that do not deviate from the spirit and principles of the present invention should be equivalent replacement methods and are included in the protection scope of the present invention.

Claims

1. An anti-hair loss composition, characterized in that: The composition comprises the following components by weight percentage: 12-20% plant extract; 0.3-1.0% moisturizer; 0.05-0.3% penetrant; 0.3-0.8% conditioner; 0.5-1.0% preservative; 0.02-0.05% colorant and the balance of water; The plant extracts are grape seed extract, Polygonum multiflorum root extract, Ganoderma lucidum root extract, Saw palmetto fruit extract, Equisetum arvense leaf extract and Ligusticum chuanxiong extract in a mass ratio of 1:3-5:2-3:1-3:1-3:2-5; The penetrant is a mixture of tanshinone, tetrahydropiperine and inositol in a mass ratio of 2-3:2:1; The conditioning agent is a mixture of hydrolyzed glucosaminoglycan and betaine in a mass ratio of 1:1; The mass ratio of the penetrant to the conditioner is 1:2-3.

2. The anti-hair loss composition according to claim 1, characterized in that: The invention comprises the following components by weight percentage: 15-18% of plant extract, 0.3-0.6% of moisturizing agent, 0.1-0.2% of penetrant, 0.4-0.6% of conditioning agent, 0.6-0.8% of preservative, 0.03-0.05% of colorant and the balance of water.

3. The anti-hair loss composition according to claim 1, characterized in that: The plant extracts are grape seed extract, Polygonum multiflorum root extract, Ganoderma lucidum root extract, Saw palmetto fruit extract, Equisetum arvense leaf extract and Ligusticum chuanxiong extract in a mass ratio of 1:4:2:2:1:

5.

4. The anti-hair loss composition according to claim 1, characterized in that: The moisturizer is selected from one or more of butylene glycol, glycerin and hyaluronic acid.

5. The anti-hair loss composition according to any one of claims 1 to 4, characterized in that: The anti-hair loss composition comprises the following components by weight percentage: Grape seed extract 1.2%, Polygonum multiflorum root extract 4.8%, Ganoderma lucidum root extract 2.4%, Saw palmetto fruit extract 2.4%, Equisetum arvense leaf extract 1.2%, Ligusticum chuanxiong extract 6%, Butylene glycol 0.375%, Glycerin 0.125%, Tanshinone 0.9%, Tetrahydropiperine 0.6%, Inositol 0.3%, Hydrolyzed glycosaminoglycan 0.25%, Betaine 0.25%, Ethylhexylglycerin 0.12%, Parahydroxyacetophenone 0.48%, Colorant 0.04% and Water as the balance.

6. The method for preparing the anti-hair loss composition according to any one of claims 1 to 4, characterized in that: The steps include: (1) Weigh the amount of conditioning agent and water in the formula into a stirring pot, soak for 30 minutes, then add the penetrant, slowly stir and heat to 85° C., keep stirring for 30 minutes, then add the preservative, moisturizer and plant extract, and continue to keep stirring for 30 minutes. After all components are evenly dissolved, start to cool down; (2) When the temperature drops to 45° C., a colorant is added and stirred evenly, and then the temperature is further lowered to room temperature to obtain the anti-hair loss composition.

7. Use of the anti-hair loss composition according to any one of claims 1 to 4 or the anti-hair loss composition prepared by the preparation method according to claim 6 in preparing hair care products.

8. The use according to claim 7, characterized in that: The hair washing and care products include shampoo, scalp care solution, hair conditioner or hair treatment cream.

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