Magnetic artificial retina and manufacturing method thereof

Abstract

The present application relates to the technical field of stimulating medical devices, and is related to implanted stimulators. A magnetic artificial retina and a method for manufacturing the same are provided, wherein the artificial retina comprises a retinal stimulator and an auxiliary locator. The retinal stimulator comprises an inner magnetic part and an electrode portion, wherein the inner magnetic part is arranged on the inner side of the electrode portion. The auxiliary locator comprises an outer magnetic part and a locator housing, wherein the locator housing wraps the outer magnetic part, and a curved protrusion is formed on one side of the locator housing that wraps one end of the outer magnetic part for being arranged close to the eyeball. The inner magnetic part and the outer magnetic part can be magnetically adsorbed together. The magnetic artificial retina can use magnetic attraction to place the retinal stimulator on the patient's eyeball, which is easy to operate and causes less damage to the eyeball.

Description

Technical Field

[0001] The present application relates to the technical field of stimulating medical devices, and is related to implanted stimulators, and in particular to a magnetic artificial retina and a method for manufacturing the same. Background Art

[0002] In clinical treatment, it is often necessary to implant some artificial medical devices into the human body to help patients recover or restore certain physiological functions. Artificial retinas usually include retinal stimulators, which can help patients with impaired vision due to aging or congenital macular retinopathy to restore functional vision.

[0003] The stimulation area of ​​the retinal stimulator of the artificial retina usually corresponds to the retinal macular area in the eye and is close to it to obtain a better stimulation effect. The traditional methods of fixing the retinal stimulator during implantation include suturing, fixing nails, etc. Among them, the suturing fixation method is very likely to cause irreversible damage to the thinner and more fragile retinal parts, and the suturing operation process is very complicated and has a high surgical risk. The fixing method of using fixing nails to fix the retinal stimulator to the eyeball tissue usually designs the nail tip to be conical and the bottom area of ​​the cone is larger than the cross-sectional area of ​​the nail rod to prevent the fixing nail from coming out after implantation. Setting fixing nails can easily cause damage to the retina. At the same time, the fixing nails are usually set at the edge of the stimulation area, which may cause the retinal stimulator to be far away from the retinal tissue in actual operation, affecting the treatment effect. The use of fixing nails will also increase the volume of the retinal stimulator, thereby increasing the risk of surgery. Both of the above-mentioned fixing schemes for retinal stimulators make it difficult to remove the retinal stimulator. When the retinal stimulator fails or reaches the end of its life and needs to be replaced, the above-mentioned fixing methods will increase the difficulty and risk of the retinal stimulator replacement operation.

[0004] On the other hand, in order to achieve better therapeutic effects, it is necessary to make the stimulating electrodes of the retinal stimulator as close to or even fit the retina as possible. Since the wall of the eyeball is an arc surface, the retinal stimulator often needs to use flexible electrodes or hard electrodes that form a curved surface so that the retinal stimulator can fit the eyeball. Among them, flexible electrodes often use fixing pins to closely fit the stimulation point to the retina. This method has the disadvantages that the retinal stimulator is prone to damage such as cracking and breaking, cannot be reused, and the number of electrodes is limited. Curved hard electrodes (such as the Utah electrode based on silicon material, Utahelectrode, "Implantable Neural Microelectrodes". 2020.Vol.34, No.1 "Materials Guide") are often difficult to process and have high production costs.

[0005] CN208838247U discloses a silicone-encapsulated artificial retina implant, which includes a coil base and a neural electrode. The coil base includes a transmission coil and a silicone sheet sleeve that matches the shape of the eyeball, and the transmission coil is encapsulated in the silicone sheet sleeve. The two ends of the silicone sheet sleeve are connected by a bandage, and the silicone sheet sleeve can be fixed to the eyeball through the bandage. The neural electrode includes a silicone arc sleeve and an electrode plate. The electrode plate is arranged in the silicone arc sleeve, one end of the silicone arc sleeve is connected to the side wall of the integrated package body, and the other end of the silicone arc sleeve matches the shape of the eyeball and is provided with a groove. One end of the electrode plate extends out of the silicone arc sleeve and is connected to the substrate in the integrated package body, and the other end of the electrode plate is provided with a stimulation part that can contact the eyeball, and the stimulation part is located in the groove. A titanium nail hole is penetrated through the neural electrode, and a titanium nail that can be fixed to the eyeball is penetrated in the titanium nail hole.

[0006] The silicone-encapsulated artificial retinal implant disclosed in the above utility model uses a combination of titanium nails and bandages to fix the neural electrodes (i.e., retinal stimulators), which still has the aforementioned defects of using fixing nails to fix retinal stimulators. In addition, the electrode plate of the implant still needs to form a curved surface that matches the shape of the eyeball, which still has the disadvantages of high processing difficulty and high production cost. Summary of the invention

[0007] This application is made in view of the above-mentioned state of the prior art. The purpose of this application is to provide a magnetic artificial retina, which can use magnetic suction to set a retinal stimulator on the patient's eyeball, which is easy to operate and causes less damage to the eyeball.

[0008] The present application also provides a method for manufacturing the above-mentioned magnetic artificial retina.

[0009] The present application provides a magnetic artificial retina, which includes a retinal stimulator and an auxiliary locator, wherein the retinal stimulator includes an inner magnetic part and an electrode part, wherein the inner magnetic part is arranged on the inner side of the electrode part, and the auxiliary locator includes an outer magnetic part and a locator shell, wherein the locator shell wraps the outer magnetic part, and a surface of one end of the locator shell wraps the outer magnetic part and is used for being arranged close to the eyeball, and a curved protrusion is formed on the surface, wherein the inner magnetic part and the outer magnetic part can be magnetically adsorbed together.

[0010] In at least one possible embodiment, the electrode portion is a hard electrode portion, which includes a hard electrode substrate and a plurality of hard stimulation electrodes, or the electrode portion is a flexible electrode portion, which includes a flexible electrode substrate and a plurality of flexible stimulation electrodes.

[0011] In at least one possible embodiment, the retinal stimulator also includes: an adhesive layer, which connects the internal magnetic part to the inner side of the electrode part; a chip, which is connected to the electrode part and is used to send a signal to the electrode part; a packaging layer, which is connected to the electrode part to encapsulate the internal magnetic part and the chip; and a stimulator housing, which is connected to the electrode part to accommodate the packaging layer, and at least one of the stimulator housing, the adhesive layer, the packaging layer and the locator housing is made of a biocompatible material.

[0012] In at least one possible implementation, the inner magnetic component and / or the outer magnetic component is a high temperature resistant magnetized magnetic component.

[0013] In at least one possible embodiment, one or more through holes are formed at one end of the locator housing that does not include the external magnetic member, for connecting the auxiliary locator to the periphery of the eyeball.

[0014] In at least one possible embodiment, the auxiliary locator also includes a support member for maintaining the shape of the auxiliary locator, the support member includes a support member head and a support member tail, the support member head is a planar structure, the external magnetic member is connected to the support member head, and the support member tail is a curved structure.

[0015] In at least one possible embodiment, the surface of the inner magnetic part is covered with an inner magnetic part film layer, which is a biocompatible material, and / or the surface of the outer magnetic part is covered with an outer magnetic part film layer, which is a biocompatible material.

[0016] The present application also provides a method for manufacturing a magnetic artificial retina, the magnetic artificial retina comprising a retinal stimulator and an auxiliary locator, the manufacturing of the retinal stimulator comprising the following steps: A1: using an adhesive to connect the inner magnetic part to the inner side of the electrode part; A2: forming a stimulator housing by injection molding, the stimulator housing connecting the electrode part and accommodating the inner magnetic part. The manufacturing of the auxiliary locator comprises the following steps: B1: providing an outer magnetic film layer on the surface of the outer magnetic part; B2: forming a locator housing by injection molding, the locator housing wrapping the outer magnetic part and the support part, one end of the support part being connected to the outer magnetic part.

[0017] In at least one possible embodiment, the method for manufacturing a magnetic artificial retina further includes: before step A1, electrically connecting the chip to the electrode portion; between step A1 and step A2, connecting the electrode portion to the packaging layer.

[0018] In at least one possible embodiment, the method for manufacturing a magnetic artificial retina further includes: before step A1, depositing an inner magnetic component film layer on the surface of the inner magnetic component by using physical vapor deposition or chemical vapor deposition.

[0019] The magnetic artificial retina provided in the present application can use magnetic suction to set the retinal stimulator on the patient's eyeball. Compared with the existing method of fixing the retinal stimulator by suturing or fixing nails, this technical solution has a good attachment effect, less damage to the eyeball, more convenient surgical operation and easy removal of the retinal stimulator. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] Figure 1 It is a schematic diagram of the structure of an artificial retina according to one embodiment of the present application.

[0021] Figure 2 It is a schematic structural diagram of an artificial retina from another perspective according to one embodiment of the present application.

[0022] Figure 3 It is a schematic diagram of the internal structure of an auxiliary locator according to one embodiment of the present application.

[0023] Figure 4 Schematic diagram of the internal structure of the retinal stimulator according to the first embodiment of the present application.

[0024] Figure 5 Schematic diagram of the internal structure of a retinal stimulator according to the second embodiment of the present application.

[0025] Figure 6 Schematic diagram of the internal structure of a retinal stimulator according to the third embodiment of the present application.

[0026] Description of Reference Numerals

[0027] 100 Eyeball

[0028] 10. Retinal Stimulator

[0029] 11 Internal magnetic parts

[0030] 12 Internal magnetic film layer

[0031] 13 Stimulator housing

[0032] 131 Stimulator bulge

[0033] 14 Adhesive layer

[0034] 15 Electrode

[0035] 151 Hard Electrode Substrate

[0036] 152 Rigid Stimulation Electrode

[0037] 153 Flexible electrode substrate

[0038] 154 Flexible Stimulation Electrode

[0039] 16 Chip

[0040] 17 Encapsulation layer

[0041] 18 Lead

[0042] 20 Auxiliary positioner

[0043] 21 External magnetic parts

[0044] 22 External magnetic film layer

[0045] 23 Support

[0046] 231 Support head

[0047] 232 Support tail

[0048] 24 Positioner housing

[0049] 241 Surface convexity

[0050] 25 Through Holes

[0051] 30 Package

[0052] 40 Wire

[0053] 50 Connecting belt DETAILED DESCRIPTION

[0054] The exemplary embodiments of the present application are described below with reference to the accompanying drawings. It should be understood that these specific descriptions are only used to teach those skilled in the art how to implement the present application, and are not intended to exhaust all possible methods of the present application, nor to limit the scope of the present application.

[0055] The embodiments of the present application provide a magnetic artificial retina (hereinafter, sometimes referred to as "artificial retina"), such as Figure 1 and Figure 2 As shown, it can include a retinal stimulator 10 and an auxiliary locator 20. The retinal stimulator 10 can be arranged inside the eyeball 100, and in particular, can be arranged in the macular area of ​​the inner retina of the eyeball. One end of the auxiliary locator 20 can be arranged at the sclera outside the eyeball corresponding to the retinal macular area.

[0056] like Figures 4 to 6As shown, the retinal stimulator 10 may include an inner magnetic part 11, a stimulator housing 13, an adhesive layer 14 and an electrode part 15. The inner magnetic part 11 is arranged on the inner side of the electrode part 15. The adhesive layer 14 can be adhered to and connected to the inner magnetic part 11. The electrode part 15 can be arranged on a side of the retina of the retinal stimulator 10 close to the eyeball 100, and can be attached to the retina (particularly the macula). The stimulator housing 13 can be connected to the electrode part 15 to form a cavity to accommodate the inner magnetic part 11 and other retinal stimulation components.

[0057] Preferably, a stimulator protrusion 131 may be formed on a side of the stimulator housing 13 away from the inner wall of the eyeball to facilitate clamping of the retinal stimulator 10 .

[0058] Regarding the specific structure of the retinal stimulator 10, three specific embodiments are given below.

[0059] First embodiment

[0060] like Figure 4 As shown, the retinal stimulator 10 provided in the first embodiment of the present application may further include a chip 16 and a packaging layer 17. The electrode portion 15 is a hard electrode portion, which may include a hard electrode substrate 151 and a hard stimulation electrode 152. A plurality of hard stimulation electrodes 152 may be provided on the hard electrode substrate 151.

[0061] The inner magnetic member 11 can be connected to the back side of the chip 16 (the side away from the electrode part 15 is the back side) through the adhesive layer 14. The chip 16 can be connected to the inner side of the electrode part 15. For example, the chip 16 can be connected to the electrode part 15 by flip-chip bonding. The chip 16 can send an electrical signal to the electrode part 15 to control the operation of the electrode part 15 and stimulate the patient's retina to achieve a therapeutic effect or function.

[0062] The packaging layer 17 can be connected to the hard electrode substrate 151, and the internal magnetic component 11 and the chip 16 can be packaged between the packaging layer 17 and the hard electrode substrate 151. The packaging layer 17 can be made of glass, ceramic, metal, etc., and can be airtightly packaged by laser welding, metal bonding, brazing, etc.

[0063] Preferably, the adhesive layer 14 can be silicone or epoxy resin, etc., and can be silicone or epoxy resin with good biocompatibility in particular. It is understood that materials with good biocompatibility can avoid adverse reactions such as allergies and rejection, increase the service life of the artificial retina, etc. Exemplarily, the biocompatible silicone can be a single-component or two-component silicone, and can be a high-temperature curing or room-temperature curing silicone. The biocompatible epoxy resin can be a single-component or two-component epoxy resin, and can be a high-temperature curing or room-temperature curing epoxy resin.

[0064] Preferably, the material of the hard stimulation electrode 152 may be a biocompatible material, for example, titanium, gold, platinum, platinum-iridium alloy, iridium oxide, and the like.

[0065] Preferably, the chip 16 may be an ASIC chip (Application Specific Integrated Circuit).

[0066] Second embodiment

[0067] Refer to the following Figure 5 The second embodiment according to the present application is described. Components having the same or similar structures or functions as those in the first embodiment are marked with the same reference numerals, and detailed descriptions of these components are omitted.

[0068] In this embodiment, the internal magnetic member 11 is directly connected to the hard electrode substrate 151 through the adhesive layer 14, and the chip 16 is connected to the hard stimulation electrode 152 in the form of wire bonding through the lead 18. That is, the surface pads of the chip 16 can be connected to the pads of the hard stimulation electrode 152 through the lead 18. The lead 18 can be a welding material allowed for active implantable medical devices, such as aluminum wire, gold wire, platinum wire, platinum-iridium alloy wire, etc.

[0069] In this embodiment, the chip 16 may be disposed on the back side of the electrode substrate 151 , in parallel with or separated from the inner magnetic member 11 , instead of being disposed between the electrode substrate 151 and the inner magnetic member 11 as in the first embodiment.

[0070] Third embodiment

[0071] Refer to the following Figure 6 The third embodiment of the present application is described. Components having the same or similar structures or functions as those in the first embodiment are denoted by the same reference numerals, and detailed descriptions of these components are omitted.

[0072] In this embodiment, the electrode portion 15 is a flexible electrode portion, and the electrode portion 15 may include a flexible electrode substrate 153 and a flexible stimulation electrode 154. The surface of the inner magnetic member 11 may be covered with the inner magnetic member film layer 12. In this embodiment, the chip 16 may not be provided in the retinal stimulator 10, and the electrode portion 15 may be connected to an external chip using a wire. In this embodiment, a flexible package may be used, and the flexible package layer may be made of an organic polymer material with good biocompatibility, such as polyimide (PI) and polyparaxylene (Parylene).

[0073] It should be understood that some aspects or features of the above-mentioned embodiments may be appropriately combined.

[0074] For example, when the diameter of the eyeball is 24 mm, the radial length of the retinal stimulator 10 may be 5 mm, and the distance between the retinal stimulator 10 and the retina (macular area) of the fundus may be 0.26 mm.

[0075] Further, such as Figure 2 and Figure 3 As shown, the auxiliary locator 20 may include an external magnetic member 21, a support member 23, and a locator housing 24. The external magnetic member 21 may attract the internal magnetic member 11, that is, the magnetic directions of the external magnetic member 21 and the internal magnetic member 11 are the same. After the artificial retina is implanted into the eyeball, the retinal stimulator 10 may be positioned at a suitable position inside the eyeball 100 by relying on the magnetic attraction between the internal magnetic member 11 and the external magnetic member 21.

[0076] The support member 23 can help the auxiliary locator 20 maintain hardness and shape, and it can include a support member head 231 and a support member tail 232. The support member head 231 can be a planar structure so that the external magnetic member 21 can be set. It can be understood that the support member 23 and the external magnetic member 21 can be connected by gluing, or the locator shell 24 can be relatively fixed by the locator shell 24 when the locator shell 24 is injection molded. The support member tail 232 can be a curved surface structure, and its shape can be the same or close to the curvature of the periphery of the eyeball (especially the periphery in the horizontal direction) so that the auxiliary locator 20 can be set outside the eyeball 100. The locator shell 24 can wrap the external magnetic member 21 and the support member 23, and the inner side of one end of the locator shell 24 that wraps the external magnetic member 21 (the side that is curved in an arc and points to the center of the circle is the inner side, that is, the side close to the eyeball is the inner side) can form a curved protrusion 241. It can be understood that the curved protrusion 241 can push up the wall of the eyeball toward the inside of the eyeball, so that the inner wall of the eyeball (retina) fits or approaches the retinal stimulator 10. Using the curved protrusion 241 to push up the inner wall of the eyeball inward can make the retinal stimulator and the retina fit effectively without using a flexible electrode or a hard electrode with a curved surface, which can reduce the processing difficulty and production cost of the electrode part.

[0077] It is understood that the positioner housing 24 can be made of a soft material with good biocompatibility, and the support member 23 can support the auxiliary positioner 20 to maintain its shape. In this embodiment, the shape of the auxiliary positioner 20 is roughly an arc with a central angle of 90 degrees. It is not excluded that the shape of the auxiliary positioner 20 (especially its positioner housing 24) can be roughly an arc with a central angle of 120 degrees, 180 degrees, etc. Figure 2As shown, one end of the housing 24 of the auxiliary locator 20 that does not include the external magnetic member 21 may form one or more through holes 25 (exemplarily, 4 in the figure), and the through holes may be used to position and connect the auxiliary locator 20 to the outside of the eyeball 100 by suturing or the like. The through hole 25 may not pass through the support member 23 to avoid exposure of the internal components of the auxiliary locator 20. It can be understood that the through hole 25 of the auxiliary locator 20 may be away from the macular area of ​​the retina, and the aperture of the through hole may be smaller, so it is less damaging to the eyeball (especially near the macular area of ​​the retina) than using a fixing pin to fix the retinal stimulator, and the difficulty and risk of the operation are also lower.

[0078] It is understandable that the inner magnetic member 11 and the outer magnetic member 21 can be magnetized magnetic sheets or unmagnetized magnetic sheets. Preferably, the inner magnetic member 11 and / or the outer magnetic member 21 can be magnetized and high temperature resistant magnetic sheets, such as magnetized strontium ferrite magnetic sheets or magnetized samarium cobalt magnetic sheets, to avoid the subsequent magnetization affecting other electronic components and the subsequent high temperature process on the wall causing the magnetic member to demagnetize.

[0079] It can be understood that the tissue outside the fundus where the auxiliary locator 20 is located is soft and can accommodate an implant of a certain size, so the size of the external magnetic member 21 can be flexibly adjusted within a certain range as needed. At the same time, the size and type of the magnetic member can be selected in a wide range, and the magnetic sheet suitable for different patients can be customized by adjusting the size and type of the external magnetic member.

[0080] Preferably, the surfaces of the inner magnetic member 11 and the outer magnetic member 21 may be covered with a film layer (especially when the inner magnetic member 11 is not airtightly packaged, a film layer needs to be covered on the outer surface of the inner magnetic member 11). For example, Figure 3 and Figure 6 As shown in , the surface of the inner magnetic part 11 can be covered with an inner magnetic part film layer 12, and the surface of the outer magnetic part 21 can be covered with an outer magnetic part film layer 22. The inner magnetic part film layer 12 and the outer magnetic part film layer 22 can be biocompatible film layers, that is, they are made of materials with good biocompatibility. The film layer can be a metal film layer, such as titanium (Ti), gold (Au), platinum (Pt), iridium (Ir), etc. An organic material film layer can also be selected, such as polyimide (PI), polyparaxylene (Parylene), polytetrafluoroethylene (PTFE), etc. Setting a film layer with good biocompatibility can avoid adverse reactions such as allergies and rejection, and increase the service life of the artificial retina.

[0081] Preferably, the support member 23 can be made of a material with good biocompatibility, such as a polymer material or a metal material. For example, the polymer material can be polytetrafluoroethylene (PTFE), polyvinyl alcohol (PVA), etc., and the metal material can be titanium (Ti), gold (Au), platinum (Pt), etc.

[0082] Preferably, the stimulator housing 13 and the locator housing 24 can be made of biocompatible silicone, for example, single-component or two-component silicone, high-temperature curing silicone or room-temperature curing silicone. Alternatively, other suitable biocompatible materials can be used.

[0083] It is understandable that Figure 1 and Figure 2 As shown, the artificial retina of the present application may also include a package 30, which may be connected to the retinal stimulator 10 via a wire 40, and the package 30 may also be connected to a connecting belt 50, which may at least partially surround the periphery of the eyeball to assist in placing the retinal stimulator 10 and the package 30 on the eyeball. When using the artificial retina, it may also be used in conjunction with an external camera or other device, such as sending image information to the artificial retina through a camera on glasses in the form of wireless transmission.

[0084] The embodiment of the present application also provides a method for manufacturing a magnetic artificial retina, wherein the manufacturing of the retinal stimulator 10 may include the following steps:

[0085] A1: The inner magnetic member 11 is connected to the inner side of the electrode portion 15 using an adhesive.

[0086] A2: The stimulator housing 13 is formed by injection molding, and the stimulator housing 13 is connected to the electrode part 15 and accommodates the inner magnetic part 11.

[0087] The manufacturing of the auxiliary positioner 20 may include the following steps:

[0088] B1: Depositing the outer magnetic component film layer 22 on the surface of the outer magnetic component 21 by physical vapor deposition or chemical vapor deposition. For example, magnetron sputtering equipment, evaporation equipment, etc. may be used.

[0089] B2: The positioner housing 24 is formed by injection molding, and the positioner housing 24 wraps the external magnetic member 21 and the support member 23 , and one end of the support member is connected to the external magnetic member 21 .

[0090] When the electrode portion 15 of the retinal stimulator 10 is a hard electrode portion (hard package), before step A1, the chip 16 may be electrically connected to the electrode portion 15. Between steps A1-A2, the electrode portion 15 may be connected to the package layer 17.

[0091] When the electrode portion 15 of the retinal stimulator 10 is a flexible electrode portion (flexible package), before step A1, the inner magnetic component film layer 12 may be deposited on the surface of the inner magnetic component 11 by using physical vapor deposition or chemical vapor deposition.

[0092] It can be understood that based on the specific structure of the aforementioned artificial retina, its manufacturing method may also include the steps of drilling a hole in the locator housing 24, placing the retinal stimulator 10 and / or the auxiliary locator 20 into a magnetizer to magnetize the inner magnetic part 11 and the outer magnetic part 21, etc.

[0093] The following briefly describes some of the beneficial effects of the above-mentioned embodiments of the present application.

[0094] The embodiment of the present application provides a magnetic suction type artificial retina and a manufacturing method thereof, which uses a magnetic suction scheme to set the retinal stimulator to the retina using magnetic suction force. Compared with the existing method of fixing the retinal stimulator by suturing or fixing nails, this technical solution has a good attachment effect, less damage to the eyeball, more convenient surgical operation, and easy removal of the retinal stimulator. At the same time, the artificial retina uses the curved protrusion 241 to push the inner wall of the eyeball inward, so that the retinal stimulator can be effectively attached to the retina without using a flexible electrode or a hard electrode forming a curved surface, thereby reducing the processing difficulty and production cost of the retinal stimulator.

[0095] It is understood that in the present application, when the number of parts or components is not particularly limited, the number may be one or more, and the multiple here means two or more. For the case where the number of parts or components shown in the drawings and / or described in the specification is a specific number such as two, three, four, etc., the specific number is usually exemplary and not restrictive, and it can be understood as multiple, that is, two or more, but this does not mean that the present application excludes the case of one.

[0096] It should be understood that the above embodiments are merely exemplary and are not intended to limit the present application. Those skilled in the art may make various modifications and changes to the above embodiments under the guidance of the present application without departing from the scope of the present application.

Claims

1. A magnetic artificial retina, characterized in that: It includes a retinal stimulator (10) and an auxiliary positioning device (20), The retinal stimulator (10) comprises an internal magnetic component (11), an electrode portion (15), a chip (16) and a packaging layer (17). The inner magnetic member (11) is arranged on the inner side of the electrode portion (15). The chip (16) is connected to the electrode portion (15) and is used to send a signal to the electrode portion (15). The encapsulation layer (17) is connected to the electrode portion (15) to encapsulate the inner magnetic member (11) and the chip (16). The auxiliary positioner (20) comprises an external magnetic member (21) and a positioner housing (24). The locator housing (24) wraps the external magnetic member (21), and a curved protrusion (241) is formed on a surface of one end of the locator housing (24) wrapping the external magnetic member (21) and being arranged close to the eyeball. The retinal stimulator (10) is used to be arranged on the retina inside the eyeball, and the auxiliary positioner (20) is used to be arranged on the sclera of the eyeball. The inner magnetic component (11) and the outer magnetic component (21) can be magnetically attracted together.

2. The magnetic artificial retina according to claim 1, characterized in that: The electrode portion (15) is a hard electrode portion, and the electrode portion (15) comprises a hard electrode substrate (151) and a plurality of hard stimulation electrodes (152), or The electrode portion (15) is a flexible electrode portion, and the electrode portion (15) comprises a flexible electrode substrate (153) and a plurality of flexible stimulation electrodes (154).

3. The magnetic artificial retina according to claim 1, characterized in that: The retinal stimulator (10) further comprises: an adhesive layer (14) connecting the inner magnetic member (11) to the inner side of the electrode portion (15), and a stimulator housing (13), the stimulator housing (13) being connected to the electrode portion (15) to accommodate the packaging layer (17), At least one of the stimulator housing (13), the adhesive layer (14), the packaging layer (17) and the locator housing (24) is made of a biocompatible material.

4. The magnetic artificial retina according to claim 1, characterized in that: The inner magnetic component (11) and / or the outer magnetic component (21) are high temperature resistant magnetized magnetic components.

5. The magnetic artificial retina according to claim 1, characterized in that: One or more through holes (25) are formed at one end of the locator housing (24) that does not include the external magnetic member (21) and are used to connect the auxiliary locator (20) to the periphery of the eyeball.

6. The magnetic artificial retina according to claim 1, characterized in that: The auxiliary positioner (20) further comprises a support member (23) for maintaining the shape of the auxiliary positioner (20). The support member (23) comprises a support member head portion (231) and a support member tail portion (232). The support member head (231) is a planar structure, and the external magnetic member (21) is connected to the support member head (231). The support member tail (232) is a curved surface structure.

7. The magnetic artificial retina according to claim 1, characterized in that: The surface of the inner magnetic member (11) is covered with an inner magnetic member film layer (12), the inner magnetic member film layer (12) is a biocompatible material, and / or The surface of the external magnetic component (21) is covered with an external magnetic component film layer (22), and the external magnetic component film layer (22) is a biocompatible material.

8. A method for manufacturing a magnetic artificial retina, characterized in that: The magnetic artificial retina comprises a retinal stimulator (10) and an auxiliary positioning device (20). The manufacturing of the retinal stimulator (10) comprises the following steps: A1: Use adhesive to connect the inner magnetic part (11) to the inner side of the electrode part (15). A2: forming a stimulator housing (13) by injection molding, wherein the stimulator housing (13) is connected to the electrode portion (15) and accommodates the inner magnetic member (11); The manufacturing of the auxiliary positioner (20) comprises the following steps: B1: an external magnetic member film layer (22) is provided on the surface of the external magnetic member (21), B2: A positioner housing (24) is formed by injection molding, wherein the positioner housing (24) wraps the external magnetic member (21) and the support member (23), and one end of the support member (23) is connected to the external magnetic member (21).

9. The method for manufacturing a magnetic artificial retina according to claim 8, characterized in that: Also includes: Before step A1, the chip (16) is electrically connected to the electrode portion (15). Between step A1 and step A2, the electrode portion (15) is connected to the encapsulation layer (17).

10. The method for manufacturing a magnetic artificial retina according to claim 8, characterized in that: Before step A1, an inner magnetic component film layer (12) is deposited on the surface of the inner magnetic component (11) by using physical vapor deposition or chemical vapor deposition.

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