A pig whole genome low-density 5K SNP chip and its application
By designing a low-density 5K SNP chip suitable for the pig genome, the problem of high cost of high-density chips is solved, low-cost and high-accuracy genome selection is achieved, and the progress of pig breeding is promoted.
Patent Information
- Application Number
- CN202310759309.8
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2023-06-26
- Publication Date
- 2025-03-21
- Estimated Expiration
- 2043-06-26
AI Technical Summary
The expensive price of high-density SNP chips limits the widespread application of genome selection technology in actual animal husbandry production. The design and application of low-density SNP chips can solve this bottleneck problem, but the existing technology lacks low-density SNP chips suitable for the pig genome.
A pig whole genome low-density 5K SNP chip was designed, containing 5603 SNP molecular markers. By screening the resequencing data of big white pigs, the chip density was reduced by FSFS and MOLO algorithms, and sites with good polymorphism and high detection rate were added to ensure the diversity and uniformity of the sites.
The genotypes of more than ones are determined at a low cost, which improves the accuracy of genome selection, promotes the realization of early selection, shortens generation intervals, and accelerates genetic progress.