A kind of preparation device of paracetamol granules

By designing a acetaminophen and chlorpheniramine maleate granule preparation device with crushing, pretreatment, granulation and sieving mechanisms, the problems of damaging the molecular structure of raw materials and low particle saturation during the extrusion process were solved, and the efficient preparation of high-quality granules and recycling of waste materials were achieved.

CN118634729BActive Publication Date: 2025-01-10SHANDONG ZIBO XINCAT PHARM CO LTD
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Patent Information

Application Number
CN202411128143.0
Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
Filing Date
2024-08-16
Publication Date
2025-01-10
Estimated Expiration
2044-08-16

AI Technical Summary

Technical Problem

Existing acetaminophen and chlorpheniramine maleate granule preparation equipment is prone to damaging the molecular structure of raw materials during the extrusion process, and the granule saturation is not high, so it is necessary to increase the extrusion force to meet the requirements.

Method used

A device for preparing acetaminophen and chlorpheniramine maleate granules was designed, which includes crushing, pretreatment, granulation, pressurization and sieving mechanisms. The raw materials are crushed by crushing blades, the raw materials are squeezed by upper and lower crushing plates in the pretreatment mechanism, the extrusion rollers and air pump in the granulation mechanism are used in conjunction with high-density rubber to achieve uniform extrusion, and the inclined screen in the sieving mechanism is vibrated to separate the crushed materials and granules.

Benefits of technology

This method achieves increased particle saturation without damaging the molecular structure of the raw materials, and recovers waste materials through a sieving mechanism, thereby improving preparation efficiency and particle quality.

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Abstract

This invention relates to the field of pharmaceutical manufacturing technology, specifically to a device for preparing acetaminophen and chlorpheniramine maleate granules, to solve the problems mentioned in the background art. To achieve the above objective, this invention provides the following technical solution: a device for preparing acetaminophen and chlorpheniramine maleate granules, comprising a body, a pulverizing mechanism fixedly connected to the upper end of the body, a pretreatment mechanism fixedly connected to the upper end of the pulverizing mechanism, a feeding port on the upper surface of the body, and a granulation mechanism rotatably connected inside the body. In this invention, when the connecting tube 2 slides, it drives the internally fixed needle tube to slide inside the connecting tube 2, simultaneously passing through the rubber sheet inside the connecting tube 2, allowing the gas in the air chamber to be transmitted through the needle tube to the sliding tube, and then through the sliding tube to the inside of the connecting tube 1. The connecting tube 1 inflates each semi-circular groove, and applies pressure to the high-density rubber, thus resulting in more saturated granules.
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Description

Technical Field

[0001] The invention relates to the technical field of medicine manufacturing, in particular to a device for preparing acetaminophen granules. Background Art

[0002] The preparation device of acetaminophen granules is a device used to produce acetaminophen granules. Acetophen granules are a commonly used medicine, which is often used to relieve symptoms such as fever, headache, nasal congestion, etc. caused by colds and flu.

[0003] At the beginning of the preparation of acetaminophen and pheniramine granules, acetaminophen and pheniramine are processed with different strengths. If the same strength is used, the internal molecular structure of the raw materials will be destroyed. At the same time, the relative extrusion force in the existing granulation mechanism may cause the particles to have low saturation, and the extrusion force needs to be increased. Summary of the invention

[0004] The object of the present invention is to provide a device for preparing acetaminophen phenazone granules to solve the problems raised in the above background technology. To achieve the above object, the present invention provides the following technical solution: a device for preparing acetaminophen phenazone granules, comprising a body, a crushing mechanism is fixedly connected to the upper end of the body, a pretreatment mechanism is fixedly connected to the upper end of the crushing mechanism, a feeding port is provided on the upper surface of the body, a granulating mechanism is rotatably connected to the inside of the body, a pressurizing mechanism is arranged inside the granulating mechanism, a screening mechanism is arranged inside the body, and a connecting mechanism is arranged between the granulating mechanism and the pressurizing mechanism;

[0005] The pulverizing mechanism comprises a pulverizing box, the pulverizing box is fixedly connected to the upper surface of the machine body, and pulverizing blades are rotatably connected inside the pulverizing box.

[0006] Preferably, the pretreatment mechanism comprises a box body, the upper surface of the box body is fixedly connected with a motor, the surface of the box body is fixedly connected with a double slide groove, the interior of the box body is slidably connected with an upper crushing plate, the interior of the box body is fixedly connected with a lower crushing plate, the lower end of the motor output shaft is fixedly connected with a rotating rod, the surface of the rotating rod is fixedly connected with a bevel gear 1, the bevel gear 1 is meshed with a bevel gear 2, the interior of the box body is rotatably connected with a rotating rod, one side of the bevel gear 2 is fixedly connected to one end of the rotating rod, the interior of the double slide groove is slidably connected with a rectangular frame, the interior of the rectangular frame is slidably connected with a square frame, connecting rods are fixedly connected on both sides of the surface of the square frame, the side surface of the connecting rod is fixedly connected to the upper crushing plate, the other end of the rotating rod is fixedly connected with a protrusion, the upper crushing plate and the lower crushing plate are each provided with two, and are symmetrically arranged, the distance between the upper crushing plate and the lower crushing plate on one side is greater than that between the upper crushing plate and the lower crushing plate on the other side, the protrusion is rotatably connected in the interior of the square frame through the rotating rod, and the lower end of the rotating rod is fixedly connected to the crushing blade.

[0007] Preferably, the granulation mechanism includes a driving motor, the driving motor is fixedly connected to the side of the machine body, a rotating rod 1 is fixedly connected to the side of the output shaft of the driving motor, a gear is fixedly connected to the surface of the rotating rod 1, an extrusion roller is fixedly connected to the other end of the rotating rod 1, a semicircular groove is provided on the surface of the extrusion roller, a high-density rubber is fixedly connected to the edge of the semicircular groove, a connecting pipe is fixedly connected to the inside of the extrusion roller, two gears and two extrusion rollers are provided, and they are symmetrically arranged, and are rotatably connected inside the machine body, and the two gears are in a meshing state.

[0008] Preferably, the boosting mechanism includes an air pump, which is fixedly connected to the other side of the machine body, a T-shaped pipe is fixedly connected to the side of the output end of the air pump, one end of the T-shaped pipe is fixedly connected to an air cavity, an extrusion block is fixedly connected to the side of the extrusion roller, the other end of the T-shaped pipe is slidably connected to a sliding rod, a spring is provided on the side of the sliding rod, and one end of the sliding rod is fixedly connected to a pressing air valve.

[0009] Preferably, the screening mechanism includes a telescopic rod, the upper end of the telescopic rod is fixedly connected to the inclined screen, the inside of the body is rotatably connected to a rotating rod 2, a transmission belt is transmitted between the rotating rod 2 and the rotating rod 1, the lower end of the body is fixedly connected to a support block, the rotating rod 2 is rotatably connected inside the support block, the other side of the rotating rod 2 is fixedly connected to a Z-shaped rod, the upper end of the support block is rotatably connected to a semicircular rod, the other end of the semicircular rod is fixedly connected to an arc-shaped slide groove, and the inside of the arc-shaped slide groove is slidably connected to an arc-shaped slider.

[0010] Preferably, the connecting mechanism includes a connecting tube 1 and a connecting tube 2, one end of the connecting tube 1 is fixedly connected to the other side of the connecting pipe and is in a connected state, the connecting tube 2 is fixedly connected to the side of the air cavity, the side of the connecting tube 1 is fixedly connected with a triangular protrusion 1, the surface of the connecting tube 2 is slidably connected with a sliding tube, the side of the sliding tube is fixedly connected with a triangular protrusion 2, the inside of the sliding tube is fixedly connected with a needle tube, the surface of the needle tube is provided with a telescopic spring, and the inside of the connecting tube 2 is fixedly connected with a rubber sheet.

[0011] Preferably, multiple groups are provided at one end of the connecting pipe, and each pipe is fixedly connected to each row of semicircular grooves and is in a connected state, the upper edge of the high-density rubber is fixedly connected to the surface of the semicircular groove, and the lower end of the high-density rubber is in a fit state with the semicircular groove.

[0012] Preferably, the Z-shaped rod is rotatably connected inside the support block via a second rotating rod, and the other end of the Z-shaped rod is fixedly connected to the side surface of the arc-shaped sliding block.

[0013] In the present invention, when the connecting tube 2 slides, the internally fixed needle tube is driven to slide inside the connecting tube 2, and at the same time, the rubber sheet inside the connecting tube 2 is passed through, so that the gas in the air cavity is transmitted to the sliding tube through the needle tube, and then transmitted to the inside of the connecting tube 1 through the sliding tube. The connecting pipeline inflates the inside of each semicircular groove through the connecting tube 1 and puts pressure on the high-density rubber, so that the extruded particles have a higher degree of fullness.

[0014] In the present invention, the upper crushing plate is driven to perform reciprocating rectangular motion inside the box through the connecting rod, and the raw materials are squeezed through the lower crushing plate to achieve the pretreatment effect without destroying the molecules inside the amine and pheniramine raw materials. Different pretreatment effects are achieved according to the different squeezing forces.

[0015] In the present invention, the arc-shaped slide groove is pushed to make the semicircular rod perform arc-shaped reciprocating motion on the upper surface of the support block. When the semicircular rod performs arc-shaped reciprocating motion, the inclined screen is squeezed to vibrate. The inclined screen moves through the telescopic rod. When the inclined screen vibrates, the crushed materials generated during granulation are separated from the particles, and the waste materials can be further recycled. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 It is a schematic diagram of the three-dimensional appearance of the present invention;

[0017] Figure 2 It is a schematic diagram of the crushing box and other structures of the present invention;

[0018] Figure 3 It is a schematic diagram of the side cross-sectional structure of the pretreatment mechanism of the present invention;

[0019] Figure 4 For the present invention Figure 3 A is a schematic diagram of the enlarged structure;

[0020] Figure 5 It is a schematic diagram of the double slide and other structures of the present invention;

[0021] Figure 6 This is a schematic diagram of the front structure of the machine body of the present invention;

[0022] Figure 7 It is a schematic diagram of the internal structure of the machine body of the present invention;

[0023] Figure 8 It is an enlarged structural schematic diagram of the granulation mechanism of the present invention;

[0024] Fig. 9 It is a schematic diagram of the side cross-sectional structure of the squeezing roller of the present invention;

[0025] Fig.10 For the present invention Fig. 9 Middle B is a schematic diagram of the enlarged structure;

[0026] Fig.11 It is a schematic diagram of the connecting pipeline and other structures of the present invention;

[0027] Fig.12 This is a schematic diagram of the cross-sectional structure of a T-shaped pipeline of the present invention;

[0028] Fig.13 It is an enlarged structural schematic diagram of the connection mechanism of the present invention;

[0029] Fig.14 It is a schematic diagram of the side cross-sectional structure of the connecting mechanism of the present invention;

[0030] Fig.15 It is a schematic diagram of the arc chute and other structures of the present invention.

[0031] In the figure: 1, machine body; 2, crushing mechanism; 3, pretreatment mechanism; 4, feeding port; 5, granulation mechanism; 6, boosting mechanism; 7, screening mechanism; 8, connecting mechanism; 21, crushing box; 22, crushing blades; 31, box body; 32, motor; 33, double slide; 34, upper crushing plate; 35, lower crushing plate; 36, rotating rod; 37, bevel gear one; 38, rotating rod; 39, bevel gear two; 310, rectangular frame; 311, connecting rod; 312, square frame; 313, bump; 51, driving motor; 52, rotating rod one; 53, gear; 54, squeezing roller; 55, semicircular groove; 56, high-density rubber; 57, connecting pipe; 61, air pump; 62. T-shaped pipe; 63. air cavity; 64. extrusion block; 65. sliding rod; 66. spring; 67. push air valve; 71. telescopic rod; 72. inclined screen; 73. transmission belt; 74. rotating rod 2; 75. support block; 76. Z-shaped rod; 77. arc-shaped slide groove; 78. arc-shaped slider; 79. semicircular rod; 81. connecting tube 1; 82. triangular protrusion 1; 83. sliding tube; 84. connecting tube 2; 85. triangular protrusion 2; 86. needle tube; 87. telescopic spring; 88. rubber sheet. DETAILED DESCRIPTION

[0032] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technical personnel in this field without creative work are within the scope of protection of the present invention.

[0033] See also Figures 1 to 15The present invention provides a technical solution: a paracetamol granule preparation device, comprising a body 1, a crushing mechanism 2 is fixedly connected to the upper end of the body 1, a pretreatment mechanism 3 is fixedly connected to the upper end of the crushing mechanism 2, a feeding port 4 is provided on the upper surface of the body 1, a granulating mechanism 5 is rotatably connected to the inside of the body 1, a pressurizing mechanism 6 is arranged inside the granulating mechanism 5, a sieving mechanism 7 is arranged inside the body 1, and a connecting mechanism 8 is arranged between the granulating mechanism 5 and the pressurizing mechanism 6;

[0034] The pulverizing mechanism 2 includes a pulverizing box 21 , which is fixedly connected to the upper surface of the machine body 1 , and a pulverizing blade 22 is rotatably connected inside the pulverizing box 21 .

[0035] The pretreatment mechanism 3 includes a box body 31, the upper surface of the box body 31 is fixedly connected to a motor 32, the surface of the box body 31 is fixedly connected to a double slide 33, the interior of the box body 31 is slidably connected to an upper crushing plate 34, the interior of the box body 31 is fixedly connected to a lower crushing plate 35, the lower end of the output shaft of the motor 32 is fixedly connected to a rotating rod 36, the surface of the rotating rod 36 is fixedly connected to a bevel gear 1 37, the bevel gear 1 37 is meshed with a bevel gear 2 39, the interior of the box body 31 is rotatably connected to a rotating rod 38, one side of the bevel gear 2 39 is fixedly connected to one end of the rotating rod 38, the interior of the double slide 33 is slidably connected to a rectangular frame 310, the interior of the rectangular frame 310 is slidably connected to a square frame 312, the surface of the square frame 312 is fixedly connected to connecting rods 311, and the connecting rods 312 are fixedly connected to the two sides of the surface. The side of the rod 311 is fixedly connected to the upper crushing plate 34, and the other end of the rotating rod 38 is fixedly connected with a protrusion 313. The upper crushing plates 34 and the lower crushing plates 35 are each provided with two, and are symmetrically arranged. The distance between the upper crushing plates 34 and the lower crushing plates 35 on one side is greater than that between the upper crushing plates 34 and the lower crushing plates 35 on the other side. The protrusion 313 is rotatably connected inside the square frame 312 through the rotating rod 38, and the lower end of the rotating rod 36 is fixedly connected to the crushing blade 22. The upper crushing plate 34 is driven to reciprocate in the box body 31 through the connecting rod 311, and the raw materials are squeezed through the lower crushing plate 35 to achieve the pretreatment effect, and the molecules inside the aminophenol and xanthine raw materials will not be destroyed. Different pretreatment effects are achieved according to the different squeezing forces.

[0036] The granulating mechanism 5 includes a driving motor 51, which is fixedly connected to the side of the machine body 1. A rotating rod 52 is fixedly connected to the side of the output shaft of the driving motor 51. A gear 53 is fixedly connected to the surface of the rotating rod 52. An extrusion roller 54 is fixedly connected to the other end of the rotating rod 52. A semicircular groove 55 is provided on the surface of the extrusion roller 54. A high-density rubber 56 is fixedly connected to the edge of the semicircular groove 55. A connecting pipe 57 is fixedly connected to the inside of the extrusion roller 54. Two gears 53 and two extrusion rollers 54 are provided, and they are symmetrically arranged. Both are rotatably connected inside the machine body 1. The two gears 53 are in a meshing state. Multiple groups are provided at one end of the connecting pipe 57, and each pipe is fixedly connected to each row of semicircular grooves 55 and is in a connected state. The upper edge of the high-density rubber 56 is fixedly connected to the surface of the semicircular groove 55, and the lower end of the high-density rubber 56 is in a fit state with the semicircular groove 55.

[0037] The boosting mechanism 6 includes an air pump 61, which is fixedly connected to the other side of the body 1. A T-shaped pipe 62 is fixedly connected to the side of the output end of the air pump 61, one end of the T-shaped pipe 62 is fixedly connected to an air cavity 63, the side of the extrusion roller 54 is fixedly connected to an extrusion block 64, the other end of the T-shaped pipe 62 is slidably connected to a slide rod 65, a spring 66 is provided on the side of the slide rod 65, and one end of the slide rod 65 is fixedly connected to a pressing air valve 67.

[0038] The screening mechanism 7 includes a telescopic rod 71, the upper end of which is fixedly connected to a sloped screen 72, a rotating rod 74 is rotatably connected inside the body 1, a transmission belt 73 is transmission-connected between the rotating rod 74 and the rotating rod 1 52, a support block 75 is fixedly connected to the bottom end of the body 1, the rotating rod 74 is rotatably connected inside the support block 75, a Z-shaped rod 76 is fixedly connected to the other side of the rotating rod 74, a semicircular rod 79 is rotatably connected to the upper end of the support block 75, and an arc-shaped slide groove 77 is fixedly connected to the other end of the semicircular rod 79. An arc-shaped slider 78 is slidably connected inside, and a Z-shaped rod 76 is rotatably connected inside the support block 75 through a rotating rod 74. The other end of the Z-shaped rod 76 is fixedly connected to the side of the arc-shaped slider 78. The arc-shaped slide groove 77 is pushed to make the semicircular rod 79 perform an arc-shaped reciprocating motion on the upper surface of the support block 75. When the semicircular rod 79 performs an arc-shaped reciprocating motion, the inclined screen 72 is squeezed to vibrate it. The inclined screen 72 moves through the telescopic rod 71. When the inclined screen 72 vibrates, the crushed materials produced during granulation are separated from the particles, and the waste materials can be further recycled.

[0039] The connecting mechanism 8 includes a connecting tube 1 81 and a connecting tube 2 84. One end of the connecting tube 1 81 is fixedly connected to the other side of the connecting pipe 57 and is in a connected state. The connecting tube 2 84 is fixedly connected to the side of the air cavity 63. The side of the connecting tube 1 81 is fixedly connected with a triangular protrusion 1 82. The surface of the connecting tube 2 84 is slidably connected with a sliding tube 83. The side of the sliding tube 83 is fixedly connected with a triangular protrusion 2 85. The interior of the sliding tube 83 is fixedly connected with a needle tube 86. The surface of the needle tube 86 is provided with a telescopic spring 87. The interior of the connecting tube 2 84 is fixedly connected with a rubber sheet 88. After the connecting tube 1 81 rotates through the sliding tube 83, The gas in the connecting pipe 57 will leak out, and then the high-density rubber 56 will recover. At the same time, the squeezed particles will be easier to detach and easier to collect. When the connecting pipe 84 slides, the internal fixed needle tube 86 will be driven to slide inside the connecting pipe 84, and at the same time, the rubber sheet 88 inside the connecting pipe 84 will be passed through the needle tube 86, so that the gas in the air cavity 63 is transmitted to the sliding tube 83 through the needle tube 86, and then transmitted to the inside of the connecting pipe 1 81 through the sliding tube 83. The connecting pipe 57 inflates the inside of each semicircular groove 55 through the connecting pipe 1 81 and puts pressure on the high-density rubber 56, so that the squeezed particles are fuller.

[0040] The use method and advantages of the present invention: When the acetaminophen phenanthellamine granule preparation device is used, the working process is as follows:

[0041] When in use, firstly, put the acetaminophen and phenanthene raw materials into both sides of the box body 31, and then start the motor 32, the motor 32 drives the rotating rod 36 to rotate, the rotating rod 36 rotates to drive the bevel gear 1 37 on the surface to rotate, when the bevel gear 1 37 rotates, it drives the meshing bevel gear 2 39 to rotate, the bevel gear 2 39 rotates through the rotating rod 38, when the rotating rod 38 rotates, it drives the protrusion 313 to rotate, when the protrusion 313 rotates to the upper and lower positions, it squeezes the square frame 312 to move up and down inside the rectangular frame 310, and when the protrusion 313 rotates to the left and right positions, it passes through the square frame 31 2. Extrude the rectangular frame 310 so that it slides left and right inside the double slide groove 33, so that the connecting rod 311 fixed on the surface of the square frame 312 will form a reciprocating rectangular motion. The connecting rod 311 will drive the upper crushing plate 34 to move back and forth inside the box body 31, and extrude the raw materials through the lower crushing plate 35 to achieve the pretreatment effect without destroying the molecules inside the aminophenol and pheniramine raw materials. According to the different extrusion forces and the different spacings between the upper crushing plate 34 and the lower crushing plate 35, the extrusion effects are different and the pretreatment forces are also different.

[0042] Then the pretreated raw material will fall into the interior of the crushing box 21 and be crushed by the crushing blades 22, and then enter the interior of the machine body 1 through the discharge port 4, and at the same time, the driving motor 51 and the air pump 61 will be started, and the driving motor 51 drives the rotating rod 52 to rotate, and the rotating rod 52 rotates to drive the gear 53 to rotate, and the two gears 53 mesh and rotate relative to each other, and at the same time drive the two squeezing rollers 54 to rotate relative to each other, and when the semicircular grooves 55 opened on the surfaces of the two squeezing rollers 54 squeeze the raw materials relative to each other, at the same time, the squeezing rollers 54 will drive the side squeezing blocks 64 to rotate, and the squeezing blocks 64 will squeeze the sliding rod 65, and the sliding rod 65 will slide inside the T-shaped pipe 62, and at the same time drive the side pressing air valve 67 to slide, so that the T-shaped pipe 62 is connected with the air cavity 63, and at this time, the air pump 61 will inflate the air cavity 63 through the T-shaped pipe 62, and at the same time, the squeezing rollers 54 will drive the internal connecting pipe 57 to rotate, and the connecting pipe 57 drives the connecting pipe 81 to rotate, and the connecting pipe 81 is connected. When the connecting pipe 1 81 rotates, the triangular protrusion 1 82 on the side first squeezes the triangular protrusion 2 85. When the triangular protrusion 2 85 is squeezed, it drives the sliding pipe 83 to slide on the surface of the connecting pipe 2 84. When the connecting pipe 2 84 is completely docked with the connecting pipe 1 81, the connecting pipe 2 84 drives the internal fixed needle tube 86 to slide inside the connecting pipe 2 84, and at the same time passes through the rubber sheet 88 inside the connecting pipe 2 84, so that the gas in the air cavity 63 is transmitted to the sliding pipe 83 through the needle tube 86, and then transmitted to the inside of the connecting pipe 1 81 through the sliding pipe 83. The connecting pipe 57 inflates the inside of each semicircular groove 55 through the connecting pipe 1 81, and puts pressure on the high-density rubber 56, so that the extruded particles are fuller. Then, after the connecting pipe 1 81 rotates around the sliding pipe 83, the gas in the connecting pipe 57 will leak out, and then the high-density rubber 56 will recover. At the same time, the squeezed particles will be easier to detach, which is convenient for collection.

[0043] At the same time, when the rotating rod 1 52 rotates, it is connected to the rotating rod 2 74 through the transmission belt 73. The rotating rod 2 74 rotates inside the support block 75 and drives the Z-shaped rod 76 to rotate. When the Z-shaped rod 76 rotates, the belt-shaped arc slider 78 rotates inside the arc slide groove 77 and pushes the arc slide groove 77 to make an arc-shaped reciprocating motion on the upper surface of the support block 75 through the semicircular rod 79. When the semicircular rod 79 reciprocates in an arc, it squeezes the inclined screen 72 to make it vibrate. The inclined screen 72 moves through the telescopic rod 71. When the inclined screen 72 vibrates, the crushed materials produced during granulation are separated from the particles, and the waste materials can be further recycled.

[0044] The above shows and describes the basic principles, main features and advantages of the present invention. Technical personnel in this industry should understand that the present invention is not limited to the above embodiments. The above embodiments and descriptions are only preferred examples of the present invention and are not used to limit the present invention. Without departing from the spirit and scope of the present invention, the present invention may have various changes and improvements, which fall within the scope of the present invention to be protected. The scope of protection of the present invention is defined by the attached claims and their equivalents.

Claims

1. A device for preparing paracetamol and chlorpheniramine granules, comprising a body (1), characterized in that: The upper end of the machine body (1) is fixedly connected to a pulverizing mechanism (2), the upper end of the pulverizing mechanism (2) is fixedly connected to a pre-treatment mechanism (3), the upper surface of the machine body (1) is provided with a feed opening (4), the interior of the machine body (1) is rotatably connected to a granulating mechanism (5), the interior of the granulating mechanism (5) is provided with a pressurizing mechanism (6), the interior of the machine body (1) is provided with a screening mechanism (7), a connecting mechanism (8) is provided between the granulating mechanism (5) and the pressurizing mechanism (6), the pulverizing mechanism (2) comprises a pulverizing box (21), the pulverizing box (21) is fixedly connected to the upper surface of the machine body (1), and the interior of the pulverizing box (21) is rotatably connected to pulverizing blades (22); The pretreatment mechanism (3) comprises a housing (31), the upper surface of the housing (31) is fixedly connected to a motor (32), the surface of the housing (31) is fixedly connected to a double slide groove (33), the interior of the housing (31) is slidably connected to an upper crushing plate (34), the interior of the housing (31) is fixedly connected to a lower crushing plate (35), the lower end of the output shaft of the motor (32) is fixedly connected to a rotating rod (36), the surface of the rotating rod (36) is fixedly connected to a bevel gear 1 (37), the bevel gear 1 (37) is meshed with a bevel gear 2 (39), the interior of the housing (31) is rotatably connected to a rotating rod (38), one side of the bevel gear 2 (39) is fixedly connected to one end of the rotating rod (38), the interior of the double slide groove (33) is slidably connected to a rotating rod (38), and the lower end of the output shaft of the motor (32) is fixedly connected to a rotating rod (36). A rectangular frame (310), wherein a square frame (312) is slidably connected inside the rectangular frame (310), connecting rods (311) are fixedly connected to both sides of the surface of the square frame (312), the side of the connecting rod (311) is fixedly connected to the upper crushing plate (34), the other end of the rotating rod (38) is fixedly connected to a protrusion (313), the upper crushing plate (34) and the lower crushing plate (35) are each provided with two, and are symmetrically arranged, the distance between the upper crushing plate (34) and the lower crushing plate (35) on one side is greater than that between the upper crushing plate (34) and the lower crushing plate (35) on the other side, the protrusion (313) is rotatably connected inside the square frame (312) via the rotating rod (38), and the lower end of the rotating rod (36) is fixedly connected to the crushing blade (22); The granulating mechanism (5) comprises a driving motor (51), the driving motor (51) being fixedly connected to a side surface of a machine body (1), a rotating rod (52) being fixedly connected to the side surface of an output shaft of the driving motor (51), a gear (53) being fixedly connected to the surface of the rotating rod (52), an extrusion roller (54) being fixedly connected to the other end of the rotating rod (52), a semicircular groove (55) being provided on the surface of the extrusion roller (54), a high-density rubber (56) being fixedly connected to the edge of the semicircular groove (55), a connecting pipe (57) being fixedly connected to the interior of the extrusion roller (54), two gears (53) and two extrusion rollers (54) being symmetrically arranged and rotatably connected to each other inside the machine body (1), and the two gears (53) being in a meshing state; The boost mechanism (6) comprises an air pump (61), the air pump (61) being fixedly connected to the other side of the machine body (1), a T-shaped pipe (62) being fixedly connected to the side of the output end of the air pump (61), one end of the T-shaped pipe (62) being fixedly connected to an air cavity (63), a side of the squeezing roller (54) being fixedly connected to an squeezing block (64), the other end of the T-shaped pipe (62) being slidably connected to a sliding rod (65), a spring (66) being provided on the side of the sliding rod (65), and one end of the sliding rod (65) being fixedly connected to a pressing air valve (67); The connecting mechanism (8) comprises a connecting tube 1 (81) and a connecting tube 2 (84); one end of the connecting tube 1 (81) is fixedly connected to the other side of the connecting pipe (57) and is in a communicating state; the connecting tube 2 (84) is fixedly connected to the side of the air cavity (63); a triangular protrusion 1 (82) is fixedly connected to the side of the connecting tube 1 (81); a sliding tube (83) is slidably connected to the surface of the connecting tube 2 (84); a triangular protrusion 2 (85) is fixedly connected to the side of the sliding tube (83); a needle tube (86) is fixedly connected to the inside of the sliding tube (83); a telescopic spring (87) is provided on the surface of the needle tube (86); and a rubber sheet (88) is fixedly connected to the inside of the connecting tube 2 (84).

2. A paracetamol granule preparation device according to claim 1, characterized in that: The screening mechanism (7) comprises a telescopic rod (71), the upper end of which is fixedly connected to a slanted screen (72), a second rotating rod (74) being rotatably connected inside the machine body (1), a transmission belt (73) being transmission-connected between the second rotating rod (74) and the first rotating rod (52), a support block (75) being fixedly connected to the bottom end of the machine body (1), the second rotating rod (74) being rotatably connected inside the support block (75), a Z-shaped rod (76) being fixedly connected to the other side of the second rotating rod (74), a semicircular rod (79) being rotatably connected to the upper end of the support block (75), an arc-shaped slide groove (77) being fixedly connected to the other end of the semicircular rod (79), and an arc-shaped slide block (78) being slidably connected inside the arc-shaped slide groove (77).

3. A paracetamol granule preparation device according to claim 1, characterized in that: A plurality of groups of connecting pipes (57) are provided at one end, and each pipe is fixedly connected to each row of semicircular grooves (55) and is in a communicating state. The upper edge of the high-density rubber (56) is fixedly connected to the surface of the semicircular groove (55), and the lower end of the high-density rubber (56) is in a fitted state with the semicircular groove (55).

4. A paracetamol granule preparation device according to claim 2, characterized in that: The Z-shaped rod (76) is rotatably connected inside the support block (75) via the second rotating rod (74), and the other end of the Z-shaped rod (76) is fixedly connected to the side of the arc-shaped sliding block (78).

Citation Information

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