A silicone oil spraying device for the inner wall of a prefilled syringe

Abstract

The present invention provides a device for spraying silicone oil on the inner wall of a prefilled syringe, which belongs to the technical field of spraying prefilled syringes, and includes a box body, a plurality of prefilled syringes, a box body, a conveying assembly, a spraying assembly and a control assembly, wherein a Class A laminar flow environment is formed inside the box body; a plurality of prefilled syringes are placed inside the box body, the conveying assembly is arranged inside the box body, the box body is placed at the upper end of the conveying assembly, and the conveying assembly is used to convey the box body to move; the spraying assembly is arranged inside the box body, and has a nozzle with a degree of freedom to move in multiple directions, the nozzle is used to extend into the prefilled syringe, and spray silicone oil on the inner wall of the prefilled syringe; the control assembly is suitable for controlling the operation of the conveying assembly and the spraying assembly, and controlling the amount of silicone oil sprayed by the nozzle. The device for spraying silicone oil on the inner wall of a prefilled syringe provided by the present invention has the technical effect of being able to spray silicone oil in a Class A laminar flow environment, improving the spraying quality, realizing automated production, and improving the spraying efficiency.

Description

Technical Field

[0001] The invention belongs to the technical field of spraying prefilled syringes, and more specifically, relates to a silicone oil spraying device for the inner wall of a prefilled syringe. Background Art

[0002] Prefilled syringes are widely used in the packaging and storage of biological drugs, and in medical and beauty products such as protein products, biological vaccines, water injections, monoclonal antibodies and gene drugs. They have a high safety factor and will not have secondary contamination. They are easy to operate and convenient to inject. The main advantage of prefilled syringes is that they can reduce the number of operating steps and time, improve safety, and reduce the risk of contamination. They are usually used in situations where a dose needs to be given quickly and accurately, such as emergency situations or hospital operating rooms. In addition, prefilled syringes can also provide patients with a more convenient way to self-administer medication, especially when dealing with chronic diseases.

[0003] During production, prefilled syringes need to be sprayed with silicone oil on their inner walls to improve the quality of the inner surface of the syringe, facilitate the addition of pistons in the next step of processing, and improve the performance and durability of the prefilled syringes. In the prior art, the methods for spraying silicone oil on the inner walls of prefilled syringes include silicone oil coating and film coating technology. Silicone oil coating is to evenly apply low-viscosity silicone oil on the inner wall of the syringe to reduce friction and reduce the interaction between the drug and the syringe. In the prior art, a sponge strip is soaked in paint, and then the sponge strip is used to apply paint to the inner wall of the syringe. Multiple prefilled syringes are coated one by one, so the operation is more troublesome and the efficiency is low. Summary of the invention

[0004] The purpose of the present invention is to provide a device for spraying silicone oil on the inner wall of a prefilled syringe, aiming to solve the technical problems of low efficiency, complicated operation and difficulty in realizing automated operation of the silicone oil spraying on the inner wall of a prefilled syringe.

[0005] To achieve the above object, the technical solution adopted by the present invention is: to provide a silicone oil spraying device for the inner wall of a prefilled syringe, comprising:

[0006] A box body, the interior of which is a closed cavity, the box body is connected to an environmental workbench, and the environmental workbench is used to provide a Class A laminar flow environment in the cavity;

[0007] Multiple prefilled syringes;

[0008] The box body is provided with a plurality of placement cavities for placing a plurality of the prefilled syringes, wherein the prefilled syringes are placed inside the placement cavities correspondingly and the upper parts are placed outside the placement cavities;

[0009] A conveying assembly is arranged inside the cavity, the box body is placed on the upper end of the conveying assembly, and the conveying assembly is used to convey the box body to move;

[0010] A spray assembly is disposed inside the cavity and has a spray head that can move in multiple directions, the spray head is used to extend into the prefilled syringe and spray silicone oil onto the inner wall of the prefilled syringe;

[0011] A control component is communicatively connected to the environmental workbench, the conveying component and the spraying component and is used to control the operation respectively, wherein the control component is suitable for controlling the amount of silicone oil sprayed by the spray head.

[0012] In a possible implementation, the box includes a plurality of plates that are spliced ​​and combined with each other, and the plurality of plates are combined to form the cavity. Two adjacent plates are connected to each other by fasteners. The gas output by the environmental workbench is connected to the cavity through a pipeline. The environmental workbench includes an air laminar flow purification device, whose operation is controlled by a control component. At least one of the plates is provided with an opening suitable for staff to enter and exit, and the box is connected to a closed door suitable for closing the opening.

[0013] In a possible implementation, the conveying component includes:

[0014] Two groups of lifting columns are arranged at intervals and have the freedom to extend and retract vertically. A driving roller is connected between the two groups of lifting columns. One group of lifting columns is connected to a driver. The power output end of the driver is connected to the driving roller and drives the driving roller to rotate in a circumferential direction. The driver is electrically connected to the control component and its operation is controlled by the control component.

[0015] Two groups of fixed columns are arranged at intervals and are arranged at intervals from the lifting columns, and a driven roller is connected between the two groups of fixed columns, and the driven roller has a circumferential rotational freedom;

[0016] The conveyor belt is wrapped around the driving roller and the driven roller, and has the freedom to circulate and rotate on the driving roller and the driven roller. The outer wall of the conveyor belt is connected to a magnetic plate, and the lower end surface of the box body is provided with a magnet, and the magnet is suitable for being magnetically attracted to the magnetic plate;

[0017] The box body is placed on the conveyor belt from a position close to the lifting columns, and the angle formed between the conveying direction of the conveyor belt and the horizontal plane is adjusted by adjusting the lifting heights of the two groups of lifting columns.

[0018] In a possible implementation, the spraying assembly includes:

[0019] A three-dimensional adjustment table, which has the freedom to adjust in three dimensions;

[0020] A rotating platform, connected to the three-dimensional adjustment platform, having the freedom to rotate circumferentially in a vertical plane, the rotating platform being electrically connected to the control component and its operation being controlled by the control component;

[0021] A manipulator connected to the rotating table, having an execution end with the degree of freedom to move in multiple directions, wherein the three-dimensional adjustment table, the rotating table and the manipulator are all electrically connected to the control component and their operation is controlled by the control component;

[0022] An oil supply assembly, the nozzle is connected to the oil supply end of the oil supply assembly through an oil supply pipe, the oil supply assembly is used to pump silicone oil to the nozzle, the oil supply assembly is electrically connected to the control assembly and the oil supply amount is controlled by the control assembly;

[0023] Wherein, the nozzle is connected to the execution end of the manipulator, and the nozzle is extended into the interior of the prefilled syringe with the help of the movement of the three-dimensional adjustment platform, the rotating platform and the manipulator, and silicone oil is sprayed onto the inner wall of the prefilled syringe.

[0024] In a possible implementation, the three-dimensional adjustment platform includes:

[0025] Two groups of columns are arranged vertically and at intervals;

[0026] Two groups of first cross beams are respectively connected to the upper ends of the two groups of columns and are arranged horizontally;

[0027] A second crossbeam, both ends of which are slidably connected to the two groups of the first crossbeams through slides, and is arranged horizontally. The second crossbeam has a sliding freedom along the length direction of the first crossbeam, and the sliding direction of the second crossbeam is defined as an X-axis;

[0028] A vertical beam, slidably connected to the side of the second cross beam through a sliding plate, the vertical beam is vertically arranged, the vertical beam has a sliding freedom along the length direction of the second cross beam, and the sliding direction of the vertical beam is defined as the Y axis;

[0029] A slider, slidably connected to the vertical beam, the slider has a sliding freedom along the height direction of the vertical beam, and the sliding direction of the slider is defined as the Z axis;

[0030] A push-up assembly, electrically connected to the second cross beam, the vertical beam and the sliding block respectively and used to control the sliding of the second cross beam, the vertical beam and the sliding block respectively;

[0031] Wherein, the rotating platform is connected to the upper end of the slider, and the control component is electrically connected to the ejection component and is used to control the sliding of the second cross beam, the vertical beam and the slider respectively.

[0032] In a possible implementation, the rotating platform includes:

[0033] An electric rotating table is arranged vertically, one end of which is a rotating end and has a circumferential rotational freedom in a vertical plane, and the other end is a fixed end, the fixed end is connected to the three-dimensional adjustment table, and the electric rotating table is electrically connected to the control component and its operation is controlled by the control component;

[0034] An arc plate, connected to the three-dimensional adjustment platform, arranged in an arc shape, forming a semi-enclosed structure for the rotating end of the electric rotating platform, surrounding the upper half of the electric rotating platform and forming a gap with the electric rotating platform, and the arc plate is provided with a long strip through hole along its arc direction;

[0035] A driving rod, one end of which is connected to the rotating end of the electric rotating table, and the other end of which passes through the long strip through hole and is connected to the manipulator. The driving rod is used to drive the manipulator to rotate with the help of the rotation of the electric rotating table. The rotation angle of the electric rotating table is less than 180°.

[0036] In a possible implementation, the oil supply assembly includes:

[0037] A carriage, the interior of which is a hollow cavity, and the carriage has the freedom to move in any direction;

[0038] A plurality of oil tanks, each disposed inside the vehicle compartment and respectively used to contain silicone oil;

[0039] A mixing tank, connected to the plurality of oil tanks through pipelines, for mixing the silicone oil inside the plurality of oil tanks;

[0040] A first branch pipe, one end of which is connected to the mixing tank and the other end of which is a free end and extends out of the carriage;

[0041] A slide rail connected to the carriage and arranged horizontally;

[0042] A second branch pipe, one end of which is connected to the mixing tank and the other end of which is a free end and extends out of the carriage, the middle portion of the second branch pipe is slidably connected to the slide rail, and the second branch pipe is used to adjust the position of its free end by sliding on the slide rail;

[0043] Among them, the oil supply end of the oil supply assembly is the free end of the first branch pipe and the free end of the second branch pipe, and the nozzle is used to connect to the free end of the first branch pipe or the free end of the second branch pipe through the oil supply pipe. The first branch pipe and the second branch pipe are both connected with a micro pump, and the micro pump is used to pump silicone oil to the nozzle and the amount of pumped silicone oil can be adjusted.

[0044] In a possible implementation, the silicone oil spraying device for the inner wall of a prefilled syringe further includes a machine vision detection component connected to the spraying component, and the machine vision detection component includes:

[0045] A detector body, used for performing machine vision inspection on the prefilled syringe located inside the box body;

[0046] A swing plate, connected to the spray assembly, is arranged horizontally, and has a swing end with the freedom to swing in an arc shape in a horizontal plane;

[0047] A bracket, connected to the swing end of the swing plate, wherein the height and length of the bracket are adjustable;

[0048] The telescopic column is arranged vertically, with the upper end connected to the bracket and the lower end used to connect to the detector body. The detector body is used to perform machine vision inspection on the prefilled syringe at different positions with the help of the swing of the swing plate, the adjustment of the bracket and the extension and retraction of the telescopic column.

[0049] In one possible implementation, the manipulator's execution end is connected to a clamp, which is used to form a clamp for the nozzle to clamp and fix the nozzle. The manipulator drives the nozzle to move, and its movement trajectory is from the bottom of the inner wall of the prefilled syringe to the top of the inner wall. The control component is used to preset the stroke and speed of the nozzle and to control the amount of silicone oil sprayed.

[0050] In a possible implementation, the silicone oil spraying device for the inner wall of the prefilled syringe further includes:

[0051] A rotating motor is connected to the clamping piece and is clamped and fixed by the clamping piece, and the bottom of the rotating motor is a rotating end;

[0052] An extension rod, one end of which is connected to the rotating end of the rotating motor and the other end is used to connect to the nozzle. The extension rod is coaxially arranged with the rotating end of the rotating motor. The outer diameter of the nozzle is smaller than the inner diameter of the prefilled syringe. The length of the extension rod is greater than the length of the prefilled syringe. The interior of the extension rod is hollow, and the oil supply pipe connected to the nozzle passes through the hollow interior of the extension rod. A mounting hole suitable for the oil supply pipe to pass through is provided on the upper part of the extension rod. The rotating motor is used to drive the nozzle to rotate circumferentially so as to evenly spray silicone oil on the inner wall of the prefilled syringe in a circumferential direction.

[0053] The beneficial effects of the silicone oil spraying device for the inner wall of a prefilled syringe provided by the present invention are as follows: compared with the prior art, the silicone oil spraying device for the inner wall of a prefilled syringe provided by the present invention comprises a box body, a plurality of prefilled syringes, a box body, a conveying assembly, a spraying assembly and a control assembly; the interior of the box body is a closed cavity, the box body is connected to an environmental workbench, and the environmental workbench is used to provide a Class A laminar flow environment in the cavity; the box body is provided with a plurality of placement cavities for placing a plurality of prefilled syringes, the prefilled syringes are correspondingly placed in the placement cavities and the upper parts are placed outside the placement cavities; the conveying assembly is arranged in the cavity, the box body is placed on the upper end of the conveying assembly, and the conveying assembly The component is used to convey the box body to move; the spraying component is arranged inside the cavity, and has a nozzle that can move freely in multiple directions. The nozzle is used to extend into the prefilled syringe and spray silicone oil onto the inner wall of the prefilled syringe; the control component is communicatively connected to the environmental workbench, the conveying component and the spraying component and is used to control the operation respectively, wherein the control component is also suitable for controlling the amount of silicone oil sprayed by the nozzle, which solves the technical problems of low efficiency of silicone oil spraying on the inner wall of the prefilled syringe, cumbersome operation, and difficulty in realizing automated operation, and has the technical effect of being able to spray silicone oil in a Class A laminar flow environment, with good spraying quality, realizing automated production, and improving spraying efficiency. BRIEF DESCRIPTION OF THE DRAWINGS

[0054] In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0055] Figure 1 A schematic diagram of the structure of a silicone oil spraying device for the inner wall of a prefilled syringe provided by an embodiment of the present invention;

[0056] Figure 2 A schematic diagram of the left side structure of a delivery component of a device for spraying silicone oil on the inner wall of a prefilled syringe provided by an embodiment of the present invention;

[0057] Figure 3 A schematic diagram of the structure of a spraying component of a silicone oil spraying device for the inner wall of a prefilled syringe provided by an embodiment of the present invention;

[0058] Figure 4 for Figure 3 A schematic diagram of the structure of a three-dimensional adjustment platform of a spraying assembly of a device for spraying silicone oil on the inner wall of a prefilled syringe is shown;

[0059] Figure 5 for Figure 3 A schematic diagram of the structure of a manipulator of a device for spraying silicone oil on the inner wall of a prefilled syringe is shown;

[0060] Figure 6 A schematic diagram of the structure of an oil supply component of a silicone oil spraying device for the inner wall of a prefilled syringe provided by an embodiment of the present invention;

[0061] Figure 7 A schematic diagram of the nozzle structure of a device for spraying silicone oil on the inner wall of a prefilled syringe provided by an embodiment of the present invention;

[0062] Figure 8 for Figure 7 A schematic diagram of the structure in which the nozzle is inserted into the prefilled syringe;

[0063] Fig. 9 A schematic diagram of the box structure of a device for spraying silicone oil on the inner wall of a prefilled syringe provided by an embodiment of the present invention;

[0064] Fig.10 A schematic structural diagram of a box body of a device for spraying silicone oil on the inner wall of a prefilled syringe provided in an embodiment of the present invention after being filled with prefilled syringes.

[0065] Description of reference numerals:

[0066] 1. Box body; 11. Environmental workbench; 12. Plate body; 13. Opening;

[0067] 2. Prefilled syringe;

[0068] 3. Box body; 31. Placement cavity; 32. Magnet;

[0069] 4. Conveying assembly; 41. Lifting column; 42. Driving roller; 43. Driver; 44. Fixed column; 45. Driven roller; 46. Conveying belt;

[0070] 5. Spraying assembly; 51. Spray head; 511. Rotating motor; 512. Extension rod; 52. Three-dimensional adjustment table; 521. Column; 522. First crossbeam; 523. Second crossbeam; 524. Vertical beam; 525. Slider; 53. Rotating table; 531. Electric rotating table; 532. Arc plate; 533. Driving rod; 54. Manipulator; 541. Clamping piece; 55. Oil supply assembly; 551. Carriage; 552. Oil tank; 553. Mixing tank; 554. First branch pipe; 555. Slide rail; 556. Second branch pipe; 56. Oil supply pipe;

[0071] 6. Machine vision detection component; 61. Detector body; 62. Swinging plate; 63. Bracket; 64. Telescopic column. DETAILED DESCRIPTION

[0072] In order to make the technical problems, technical solutions and beneficial effects to be solved by the present invention more clearly understood, the present invention is further described in detail below in conjunction with the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are only used to explain the present invention and are not intended to limit the present invention.

[0073] Please also read Figures 1 to 10 Now, a silicone oil spraying device for the inner wall of a prefilled syringe provided by the present invention is described. The device for spraying silicone oil on the inner wall of a prefilled syringe comprises a box body 1, a plurality of prefilled syringes 2, a box body 3, a conveying component 4, a spraying component 5 and a control component. The interior of the box body 1 is a closed cavity, and the box body 1 is connected to an environmental workbench 11, and the environmental workbench 11 is used to provide a Class A laminar flow environment in the cavity; the box body 3 is provided with a plurality of placement cavities 31 for placing a plurality of prefilled syringes 2, and the prefilled syringes 2 are correspondingly placed in the placement cavities 31 and the upper parts are placed outside the placement cavities 31; the conveying component 4 is arranged in the cavity, and the box body 3 is placed on the upper end of the conveying component 4, and the conveying component 4 is used to convey the box body 3 to move; the spraying component 5 is arranged in the cavity, and has a nozzle 51 with a degree of freedom to move in multiple directions, and the nozzle 51 is used to extend into the interior of the prefilled syringe 2 and spray silicone oil on the inner wall of the prefilled syringe 2; the control component is communicatively connected to the environmental workbench 11, the conveying component 4 and the spraying component 5 and is used to control the operation respectively, and the control component is also suitable for controlling the amount of silicone oil sprayed by the nozzle 51.

[0074] The present invention provides a device for spraying silicone oil on the inner wall of a prefilled syringe. Compared with the prior art, an environmental workbench 11 is provided to input sterilized and purified gas into a closed cavity to form a Class A laminar flow environment in the cavity, so that the silicone oil can be sprayed into the prefilled syringe 2 in a Class A laminar flow environment, which can meet and satisfy the processing requirements of the prefilled syringe 2, and the silicone oil can better meet the quality requirements after spraying. The present invention can realize the automatic spraying of silicone oil on the prefilled syringe 2 through the conveying component 4 and the spraying component 5 that cooperate with each other, solves the technical problems of low efficiency, cumbersome operation, and difficulty in realizing automated operation of the silicone oil spraying on the inner wall of the prefilled syringe 2, and has the technical effect of being able to spray silicone oil in a Class A laminar flow environment, with good spraying quality, realizing automated production, and improving spraying efficiency.

[0075] The environmental workbench 11 in this embodiment is a prior art product, which can disinfect and purify the air to form a sterile environment or a Class A laminar flow environment in the cavity. A box body can accommodate multiple prefilled syringes 2, which are arranged in multiple rows and staggered between two adjacent rows. The control component includes a control panel, a PLC controller, a control circuit, multiple control buttons and a display screen, which can preset the amount of silicone oil sprayed by the spray component 5, and can also control the operation of the conveying component 4 and the spray component 5, at least realizing the semi-automatic operation of the silicone oil spraying on the inner wall of the prefilled syringe 2. One end of the conveying component 4 is the input end and the other end is the output end. The box body 3 is placed at the input end. With the conveying or transmission of the conveying component 4, the box body 3 can be transported to the output end. When it is about to reach the output end, the control component controls the conveying component 4 to stop, and the spray component 5 is used to perform the spraying operation.

[0076] In order to facilitate the silicone oil spraying operation in a closed environment, in some embodiments, refer to Figure 1 The box 1 includes a plurality of plates 12 that are spliced ​​and combined with each other. The plurality of plates 12 are combined to form a cavity. Two adjacent plates 12 are connected to each other by fasteners. The gas output by the environmental workbench 11 is connected to the cavity through a pipeline. The environmental workbench 11 includes an air laminar flow purification device, and its operation is controlled by a control component. At least one plate 12 is provided with an opening 13 suitable for the staff to enter and exit. The box 1 is connected with a closed door suitable for closing the opening 13. The box 1 is convenient for disassembly and assembly. In this embodiment, the box 1 is arranged in a polygonal structure. The air laminar flow purification device built into the environmental workbench 11 is a prior art product and can continuously provide sterile air to the cavity. When the staff needs to enter and exit the cavity, they can enter the cavity by opening the closed door, and close the closed door after entering.

[0077] In some embodiments, see Figures 1 to 10The conveying assembly 4 includes two groups of lifting columns 41, two groups of fixed columns 44 and a conveyor belt 46. The two groups of lifting columns 41 are arranged at intervals and have the freedom to extend and retract vertically. A driving roller 42 is connected between the two groups of lifting columns 41. A group of lifting columns 41 is connected to a driver 43. The power output end of the driver 43 is connected to the driving roller 42 and drives the driving roller 42 to rotate in the circumferential direction. The driver 43 is electrically connected to the control assembly and its operation is controlled by the control assembly; the two groups of fixed columns 44 are arranged at intervals and are arranged at intervals from the lifting columns 41. A driven roller 45 is connected between the two groups of fixed columns 44. The driven roller 45 has Circumferential rotational freedom; the conveyor belt 46 is wrapped around the driving roller 42 and the driven roller 45, and has the freedom to circulate and rotate on the driving roller 42 and the driven roller 45. The outer wall of the conveyor belt 46 is connected to a magnetic plate, and a magnet 32 ​​is provided on the lower end surface of the box body 3, and the magnet 32 ​​is suitable for magnetic attraction on the magnetic plate; wherein the box body 3 is placed on the conveyor belt 46 from a position close to the lifting column 41, and the angle formed between the conveying direction of the conveyor belt 46 and the horizontal plane is adjusted by adjusting the lifting height of the two sets of lifting columns 41. In this embodiment, the left side of the conveying component 4 can be raised and lowered, and the left side is the input end, and its function is to facilitate the placement of the box body 3 on the conveying component 4. The lifting and lowering of the lifting column 41 does not affect normal transportation. The driver 43 is a motor that can drive the driving roller 42 to rotate, thereby driving the conveyor belt 46 to rotate, and the control component can control the rotation speed and forward and reverse rotation of the driver 43. The magnetic plates are multiple and are attached to the outer wall of the conveyor belt 46. The function of the magnetic plates is to fix the box body 3 and prevent the box body 3 from sliding during transportation. The magnet 32 ​​is also a magnetic plate that can be magnetically attracted to the magnetic plates. This arrangement can improve the stability of the conveyor assembly 4 when transporting the box body 3.

[0078] In some embodiments, see Figures 1 to 10The spraying assembly 5 includes a three-dimensional adjustment platform 52, a rotating platform 53, a manipulator 54 and an oil supply assembly 55. The three-dimensional adjustment platform 52 has the freedom to adjust in three directions; the rotating platform 53 is connected to the three-dimensional adjustment platform 52 and has the freedom to rotate in a circumferential direction in a vertical plane. The rotating platform 53 is electrically connected to the control assembly and its operation is controlled by the control assembly; the manipulator 54 is connected to the rotating platform 53 and has an execution end with the freedom to move in multiple directions. The three-dimensional adjustment platform 52, the rotating platform 53 and the manipulator 55 4 are electrically connected to the control component and their operation is controlled by the control component; the nozzle 51 is connected to the oil supply end of the oil supply component 55 through the oil supply pipe 56, and the oil supply component 55 is used to pump silicone oil to the nozzle 51. The oil supply component 55 is electrically connected to the control component and the oil supply amount is controlled by the control component; wherein, the nozzle 51 is connected to the execution end of the manipulator 54, and the nozzle 51 extends into the interior of the prefilled syringe 2 with the help of the movement of the three-dimensional adjustment platform 52, the rotating platform 53 and the manipulator 54, and sprays silicone oil on the inner wall of the prefilled syringe 2. The three-dimensional adjustment platform 52 can adjust its position in three dimensions to adjust the working position of the manipulator 54, which is convenient for silicone oil spraying. The manipulator 54 itself can also realize movement and adjustment in multiple directions, which is also convenient for silicone oil spraying. The coordinated operation of the manipulator 54 and the three-dimensional adjustment platform 52 can realize the movement and adjustment of the nozzle 51 in multiple directions, so as to facilitate the silicone oil spraying of prefilled syringes 2 in different positions and different placement postures. The oil supply assembly 55 can control the supply of silicone oil to the nozzle 51, and the oil supply amount can be controlled and adjusted. By using the control assembly to control the above load operation respectively, the automatic operation of spraying silicone oil into the prefilled syringe 2 can be realized, and the operation speed, quality and efficiency can be improved.

[0079] In some embodiments, see Figures 1 to 10The three-dimensional adjustment platform 52 includes two groups of columns 521, two groups of first beams 522, a second beam 523, a vertical beam 524, a slider 525 and a push-up assembly. The two groups of columns 521 are arranged vertically and spaced apart; the two groups of first beams 522 are respectively connected to the upper ends of the two groups of columns 521 and are arranged horizontally; the two ends of the second beam 523 are respectively connected to the two groups of first beams 522 by sliding plates, and are arranged horizontally. The second beam 523 has the freedom to slide along the length direction of the first beam 522, and the sliding direction of the second beam 523 is defined as the X axis; the vertical beam 524 is connected to the side of the second beam 523 by sliding plates, and the vertical beam 524 is arranged vertically. The vertical beam 524 has the freedom to slide along the length direction of the second beam 523. The sliding direction of the vertical beam 524 is defined as the Y axis; the slider 525 is slidably connected to the vertical beam 524, and the slider 525 has the sliding freedom along the height direction of the vertical beam 524, and the sliding direction of the slider 525 is defined as the Z axis; the ejection assembly is electrically connected to the second beam 523, the vertical beam 524 and the slider 525 respectively and is used to control their sliding respectively; wherein, the rotating table 53 is connected to the upper end of the slider 525, and the control assembly is electrically connected to the ejection assembly and is used to control the sliding of the second beam 523, the vertical beam 524 and the slider 525 respectively. The two groups of columns 521 have the same structure, and the two groups of first beams 522 have the same structure. The slide plate is slidably connected to the inner side surfaces of the two groups of first beams 522, and the two ends of the second beam 523 are connected to the slide plate, so that the second beam 523 can slide freely. A slide is also slidably connected to the side of the second crossbeam 523, and the side of the vertical beam 524 is connected to the slide. The vertical beam 524 can slide on the second crossbeam 523 with the help of the slide, and the slider 525 can slide vertically on the vertical beam 524. The sliding of the second crossbeam 523, the sliding of the vertical beam 524 and the sliding slider 525 are all achieved through a push-up assembly (which is the prior art), and the control assembly can control the pushing or extension of the push-up assembly, thereby controlling the operation of the three-dimensional adjustment platform 52, thereby realizing the movement and position adjustment of the manipulator 54 in three-dimensional directions.

[0080] In some embodiments, see Figures 1 to 10The rotating table 53 includes an electric rotating table 531, an arc plate 532 and a driving rod 533. The electric rotating table 531 is arranged vertically, one end of which is a rotating end and has a circumferential rotational freedom in a vertical plane, and the other end is a fixed end, and the fixed end is connected to the three-dimensional adjustment table 52. The electric rotating table 531 is electrically connected to the control component and its operation is controlled by the control component; the arc plate 532 is connected to the three-dimensional adjustment table 52, and is arranged in an arc shape, forming a semi-enclosed structure for the rotating end of the electric rotating table 531, surrounding the upper half of the electric rotating table 531 and forming a gap between the electric rotating table 531, and the arc plate 532 is provided with a long strip through hole along its arc direction; one end of the driving rod 533 is connected to the rotating end of the electric rotating table 531, and the other end is arranged through the long strip through hole and connected to the manipulator 54. The driving rod 533 is used to drive the manipulator 54 to rotate with the help of the rotation of the electric rotating table 531, and the rotation angle of the electric rotating table 531 is less than 180°. Because the box body 3 is arranged horizontally, and the prefilled syringe 2 is arranged vertically, if silicone oil is to be sprayed into the prefilled syringe 2, the nozzle 51 must be arranged vertically. By using the manipulator 54 in combination with the rotating table 53 and the three-dimensional adjustment table 52, the action of spraying silicone oil into the prefilled syringe 2 can be achieved. The electric rotating table 531 is a prior art product, which can rotate in a circular direction. The arc plate 532 is fixedly arranged. The electric rotating table 531 can drive the driving rod 533 to swing or rotate in a semicircular arc shape. The arc plate 532 plays a role in protecting the electric rotating table 531. A slide plate is connected to the bottom of the manipulator 54, and the slide plate can slide on the arc plate 532. Figure 3 The moving range of the middle manipulator 54 is from the left position to the right position of the electric rotating table 531, that is, the manipulator 54 has the freedom to move and adjust in this direction, the purpose of which is to facilitate the adjustment of spraying silicone oil into the prefilled syringe 2.

[0081] The manipulator 54 in this embodiment is a six-axis freedom manipulator or a manipulator arm in the prior art, which can realize position adjustment and movement in six directions, thereby facilitating silicone oil spraying.

[0082] In some embodiments, see Figures 1 to 10The oil supply assembly 55 includes a carriage 551, multiple oil tanks 552, a mixing tank 553, a first branch pipe 554, a slide rail 555 and a second branch pipe 556. The interior of the carriage 551 is a cavity, and the carriage 551 has the freedom to move in any direction; the multiple oil tanks 552 are arranged inside the carriage 551, and are respectively used to contain silicone oil; the mixing tank 553 is connected to the multiple oil tanks 552 through a pipeline, and is used to mix the silicone oil inside the multiple oil tanks 552; one end of the first branch pipe 554 is connected to the mixing tank 553, and the other end is a free end and extends out of the carriage 551; the slide rail 555 is connected to the carriage 551 and is arranged horizontally; the second branch pipe 556 is connected to the mixing tank 553 and is arranged horizontally. One end of the pipe 556 is connected to the mixing tank 553, and the other end is a free end and extends out of the carriage 551. The middle part of the second branch pipe 556 is slidably connected to the slide rail 555. The second branch pipe 556 is used to adjust the position of its free end by sliding on the slide rail 555. The oil supply end of the oil supply assembly 55 is the free end of the first branch pipe 554 and the free end of the second branch pipe 556. The nozzle 51 is used to connect the free end of the first branch pipe 554 or the free end of the second branch pipe 556 through the oil supply pipe 56. The first branch pipe 554 and the second branch pipe 556 are both connected to a micro pump, which is used to pump silicone oil to the nozzle 51 and the amount of pumped silicone oil can be adjusted. The bottom of the carriage 551 has wheels, which can move in any direction in the cavity, so as to facilitate oil supply at different positions. The multiple oil tanks 552 can contain the same type of silicone oil or different types of silicone oil. If a certain type of silicone oil is to be used, the pipeline connected to the oil tank 552 is opened to transport the silicone oil in the oil tank 552 to the mixing tank 553. If silicone oil formed by mixing two media is to be used, multiple oil tanks 552 can be used to place different media (such as silicone oil) respectively. By sucking silicone oil, different types of silicone oil are mixed in the mixing tank 553 and then input into the nozzle 51 after mixing. The nozzle 51 in this embodiment is a spray valve that can spray in the form of mist on the inner wall of the prefilled syringe 2. By setting the first branch pipe 554 and the second branch pipe 556, silicone oil can be pumped to the multiple nozzles 51. In specific use, for the unused first branch pipe 554 or the second branch pipe 556, its end is blocked with a plug to prevent oil leakage.

[0083] Specifically, if the position of the second branch pipe 556 needs to be adjusted, it can be slid on the slide rail 555 , so that the position of the second branch pipe 556 can be adjusted, which facilitates the connection with the oil supply pipe 56 .

[0084] In some embodiments, see Figures 1 to 10The silicone oil spraying device for the inner wall of the prefilled syringe 2 also includes a machine vision detection component 6 connected to the spraying component 5, and the machine vision detection component 6 includes a detector body 61, a swinging plate 62, a bracket 63 and a telescopic column 64. The detector body 61 is used to perform machine vision detection on the prefilled syringe 2 located inside the box body 3; the swinging plate 62 is connected to the spraying component 5, is arranged horizontally, and has a swinging end with a degree of freedom that can swing in an arc shape in a horizontal plane; the bracket 63 is connected to the swinging end of the swinging plate 62, and the height and length of the bracket 63 can be adjusted; the telescopic column 64 is arranged vertically, the upper end is connected to the bracket 63, and the lower end is used to connect the detector body 61. The detector body 61 is used to perform machine vision detection on the prefilled syringe 2 at different positions by swinging the swinging plate 62, adjusting the bracket 63 and extending the telescopic column 64. The detector body 61 is a prior art product, including a CCD camera capable of collecting image information of the prefilled syringe 2, an identification and analysis module, etc. A plate body is connected to the lower end of the telescopic column 64, and the size of the plate body is adapted to the size of the box body 3. A plurality of CCD cameras are arranged at the bottom of the plate body, and the arrangement form of the plurality of CCD cameras is the same as the arrangement form of the prefilled syringe 2 in the box body 3. When the box body 3 moves below the plate body, by controlling the conveying component 4 to pause, the plurality of CCD cameras can simultaneously take photos or images, collect information of the plurality of prefilled syringes 2, and then analyze the quality information of the prefilled syringes 2. Such an arrangement can improve the efficiency of information collection of the prefilled syringes 2. If the detector body 61 analyzes and judges, if there are prefilled syringes 2 with cracks or fissures in appearance, they can be quickly identified, and the staff can be reminded to take out the prefilled syringes 2 of poor quality. The swing plate 62 is a swing mechanism in the prior art, which can swing in an arc shape, and the bracket 63 is a frame or support frame that can be telescopically adjusted in the prior art, so as to adjust the height and length. The telescopic column 64 is an electric telescopic column, which can control its telescopic length, thereby controlling the height of the image collected by the CCD camera.

[0085] In some embodiments, see Figures 1 to 10 The manipulator 54 is connected to the execution end with a clamp 541, which is used to clamp the nozzle 51 to clamp and fix the nozzle 51. The manipulator 54 drives the nozzle 51 to move, and its moving trajectory is from the bottom of the inner wall of the prefilled syringe 2 to the top of the inner wall. The control component presets the stroke and speed of the nozzle 51, and is used to control the amount of silicone oil sprayed. The clamp 541 is equivalent to a clamp that can clamp and fix the nozzle 51. It can clamp the nozzle 51 and move it to the inside of the prefilled syringe 2 to perform the spraying operation.

[0086] In some embodiments, see Figures 1 to 10The present invention also includes a rotating motor 511 and an extension rod 512. The rotating motor 511 is connected to the clamping member 541 and is clamped and fixed by the clamping member 541. The bottom of the rotating motor 511 is a rotating end; one end of the extension rod 512 is connected to the rotating end of the rotating motor 511, and the other end is used to connect the nozzle 51. The extension rod 512 is coaxially arranged with the rotating end of the rotating motor 511. The outer diameter of the nozzle 51 is smaller than the inner diameter of the prefilled syringe 2. The length of the extension rod 512 is greater than the length of the prefilled syringe 2. The interior of the extension rod 512 is hollow. The oil supply pipe 56 connected to the nozzle 51 passes through the hollow interior of the extension rod 512. The upper part of the extension rod 512 is provided with a mounting hole suitable for the oil supply pipe 56 to pass through. The rotating motor 511 is used to drive the nozzle 51 to rotate in a circumferential direction so as to spray silicone oil uniformly on the inner wall of the prefilled syringe 2 in a circumferential direction. The rotating motor 511 is a prior art product, which can rotate, and its speed is controlled by the control component. The extension rod 512 is used to extend the depth of the nozzle 51 placed in the prefilled syringe 2. By reasonably adjusting and setting the control component, the movement track and stroke of the nozzle 51 can be controlled, and the amount of silicone oil sprayed can be conveniently controlled. The length of the extension rod 512 can be reasonably selected according to the length of the prefilled syringe 2.

[0087] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions and improvements made within the spirit and principles of the present invention should be included in the protection scope of the present invention.

Claims

1. A silicone oil spraying device for the inner wall of a prefilled syringe, characterized in that: include: A box body, the interior of which is a closed cavity, the box body is connected to an environmental workbench, and the environmental workbench is used to provide a Class A laminar flow environment in the cavity; Multiple prefilled syringes; The box body is provided with a plurality of placement cavities for placing a plurality of the prefilled syringes, wherein the prefilled syringes are placed inside the placement cavities correspondingly and the upper parts are placed outside the placement cavities; A conveying assembly is arranged inside the cavity, the box body is placed on the upper end of the conveying assembly, and the conveying assembly is used to convey the box body to move; A spray assembly is disposed inside the cavity and has a spray head that can move in multiple directions, the spray head is used to extend into the prefilled syringe and spray silicone oil onto the inner wall of the prefilled syringe; A control component, which is communicatively connected to the environmental workbench, the conveying component and the spraying component and is used to control the operation respectively, and the control component is also suitable for controlling the amount of silicone oil sprayed by the spray head; The silicone oil spraying device for the inner wall of the prefilled syringe also includes a machine vision detection component connected to the spraying component, and the machine vision detection component includes: A detector body, used for performing machine vision inspection on the prefilled syringe located inside the box body; A swing plate, connected to the spray assembly, is arranged horizontally, and has a swing end with the freedom to swing in an arc shape in a horizontal plane; A bracket, connected to the swing end of the swing plate, wherein the height and length of the bracket are adjustable; A telescopic column is arranged vertically, with an upper end connected to the bracket and a lower end used to connect the detector body, and the detector body is used to perform machine vision inspection on the prefilled syringe at different positions by means of the swing of the swing plate, the adjustment of the bracket and the extension of the telescopic column; The spraying assembly comprises: A three-dimensional adjustment table, which has the freedom to adjust in three dimensions; A rotating platform, connected to the three-dimensional adjustment platform, having the freedom to rotate in a circumferential direction in a vertical plane, the rotating platform being electrically connected to the control component and its operation being controlled by the control component; A manipulator connected to the rotating table, having an execution end with the degree of freedom to move in multiple directions, wherein the three-dimensional adjustment table, the rotating table and the manipulator are all electrically connected to the control component and their operation is controlled by the control component; An oil supply assembly, the nozzle is connected to the oil supply end of the oil supply assembly through an oil supply pipe, the oil supply assembly is used to pump silicone oil to the nozzle, the oil supply assembly is electrically connected to the control assembly and the oil supply amount is controlled by the control assembly; Wherein, the nozzle is connected to the execution end of the manipulator, and the nozzle is extended into the interior of the prefilled syringe by means of the movement of the three-dimensional adjustment platform, the rotating platform and the manipulator, and silicone oil is sprayed onto the inner wall of the prefilled syringe; The rotating platform comprises: An electric rotating table is arranged vertically, one end of which is a rotating end and has a circumferential rotational freedom in a vertical plane, and the other end is a fixed end, the fixed end is connected to the three-dimensional adjustment table, and the electric rotating table is electrically connected to the control component and its operation is controlled by the control component; An arc plate, connected to the three-dimensional adjustment platform, arranged in an arc shape, forming a semi-enclosed structure for the rotating end of the electric rotating platform, surrounding the upper half of the electric rotating platform and forming a gap with the electric rotating platform, and the arc plate is provided with a long strip through hole along its arc direction; A driving rod, one end of which is connected to the rotating end of the electric rotating table, and the other end of which passes through the long strip through hole and is connected to the manipulator. The driving rod is used to drive the manipulator to rotate with the help of the rotation of the electric rotating table. The rotation angle of the electric rotating table is less than 180°.

2. A silicone oil spraying device for the inner wall of a prefilled syringe as claimed in claim 1, characterized in that: The box body includes a plurality of plates that are spliced ​​and combined with each other, and the plurality of plates are combined to form the cavity. Two adjacent plates are connected to each other by fasteners. The gas output by the environmental workbench is connected to the cavity through a pipeline. The environmental workbench includes an air laminar flow purification device, and its operation is controlled by a control component. At least one of the plates is provided with an opening suitable for staff to enter and exit, and the box body is connected to a closed door suitable for closing the opening.

3. A silicone oil spraying device for the inner wall of a prefilled syringe as claimed in claim 1, characterized in that: The conveying assembly comprises: Two groups of lifting columns are arranged at intervals and have the freedom to extend and retract vertically. A driving roller is connected between the two groups of lifting columns. One group of lifting columns is connected to a driver. The power output end of the driver is connected to the driving roller and drives the driving roller to rotate in a circumferential direction. The driver is electrically connected to the control component and its operation is controlled by the control component. Two groups of fixed columns are arranged at intervals and are arranged at intervals from the lifting columns, and a driven roller is connected between the two groups of fixed columns, and the driven roller has a circumferential rotational freedom; The conveyor belt is wrapped around the driving roller and the driven roller, and has the freedom to circulate and rotate on the driving roller and the driven roller. The outer wall of the conveyor belt is connected to a magnetic plate, and the lower end surface of the box body is provided with a magnet, and the magnet is suitable for being magnetically attracted to the magnetic plate; The box body is placed on the conveyor belt from a position close to the lifting columns, and the angle formed between the conveying direction of the conveyor belt and the horizontal plane is adjusted by adjusting the lifting heights of the two groups of lifting columns.

4. A silicone oil spraying device for the inner wall of a prefilled syringe as claimed in claim 1, characterized in that: The three-dimensional adjustment platform comprises: Two groups of columns are arranged vertically and at intervals; Two groups of first cross beams are respectively connected to the upper ends of the two groups of columns and are arranged horizontally; A second crossbeam, both ends of which are slidably connected to the two groups of the first crossbeams through slides, and is arranged horizontally. The second crossbeam has a sliding freedom along the length direction of the first crossbeam, and the sliding direction of the second crossbeam is defined as an X-axis; A vertical beam, slidably connected to the side of the second cross beam through a sliding plate, the vertical beam is vertically arranged, the vertical beam has a sliding freedom along the length direction of the second cross beam, and the sliding direction of the vertical beam is defined as the Y axis; A slider, slidably connected to the vertical beam, the slider has a sliding freedom along the height direction of the vertical beam, and the sliding direction of the slider is defined as the Z axis; A push-up assembly, electrically connected to the second cross beam, the vertical beam and the sliding block respectively and used to control the sliding of the second cross beam, the vertical beam and the sliding block respectively; Wherein, the rotating platform is connected to the upper end of the slider, and the control component is electrically connected to the ejection component and is used to control the sliding of the second cross beam, the vertical beam and the slider respectively.

5. A silicone oil spraying device for the inner wall of a prefilled syringe as claimed in claim 1, characterized in that: The oil supply assembly comprises: A carriage, the interior of which is a hollow cavity, and the carriage has the freedom to move in any direction; A plurality of oil tanks, each disposed inside the vehicle compartment and respectively used to contain silicone oil; A mixing tank, connected to the plurality of oil tanks through pipelines, for mixing the silicone oil inside the plurality of oil tanks; A first branch pipe, one end of which is connected to the mixing tank and the other end of which is a free end and extends out of the carriage; A slide rail connected to the carriage and arranged horizontally; A second branch pipe, one end of which is connected to the mixing tank and the other end of which is a free end and extends out of the carriage, the middle portion of the second branch pipe is slidably connected to the slide rail, and the second branch pipe is used to adjust the position of its free end by sliding on the slide rail; Among them, the oil supply end of the oil supply assembly is the free end of the first branch pipe and the free end of the second branch pipe, and the nozzle is used to connect to the free end of the first branch pipe or the free end of the second branch pipe through the oil supply pipe. The first branch pipe and the second branch pipe are both connected with a micro pump, and the micro pump is used to pump silicone oil to the nozzle and the amount of pumped silicone oil can be adjusted.

6. A silicone oil spraying device for the inner wall of a prefilled syringe as claimed in claim 1, characterized in that: The manipulator execution end is connected to a clamping piece, which is used to form a clamp for the nozzle to clamp and fix the nozzle. The manipulator drives the nozzle to move, and its movement trajectory is from the bottom of the inner wall of the prefilled syringe to the top of the inner wall. The control component presets the stroke and speed of the nozzle, and is used to control the amount of silicone oil sprayed.

7. A silicone oil spraying device for the inner wall of a prefilled syringe as claimed in claim 6, characterized in that: The silicone oil spraying device for the inner wall of the prefilled syringe also includes: A rotating motor is connected to the clamping piece and is clamped and fixed by the clamping piece, and the bottom of the rotating motor is a rotating end; An extension rod, one end of which is connected to the rotating end of the rotating motor and the other end is used to connect to the nozzle. The extension rod is coaxially arranged with the rotating end of the rotating motor. The outer diameter of the nozzle is smaller than the inner diameter of the prefilled syringe. The length of the extension rod is greater than the length of the prefilled syringe. The interior of the extension rod is hollow, and the oil supply pipe connected to the nozzle passes through the hollow interior of the extension rod. A mounting hole suitable for the oil supply pipe to pass through is provided on the upper part of the extension rod. The rotating motor is used to drive the nozzle to rotate circumferentially so as to evenly spray silicone oil on the inner wall of the prefilled syringe in a circumferential direction.

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