Method and device for improving wireless charging efficiency of implantable medical device

Abstract

The invention provides a method and equipment for improving wireless charging efficiency of implantable medical equipment. The method comprises the following steps: acquiring an initial working frequency of the implantable medical equipment; obtaining the equivalent impedance of the external equipment; and adjusting the initial working frequency according to the equivalent impedance so as to determine the target working frequency and the target input voltage of the implantable medical device. According to the magnitude of the equivalent impedance, the input voltage is dynamically adjusted, the magnitude of the charging current of the charging coil of the in-vitro equipment is limited, and the loss of the charging coil of the in-vitro equipment and the related loss of a transmitting circuit are reduced. And meanwhile, the loss of a charging coil of the in-vivo equipment and the eddy current loss on a metal shell of the in-vivo equipment are reduced, the temperature rise of the in-vivo equipment is reduced, and the equipment always works at the highest efficiency point along with the change of the charging distance, so that the wireless charging efficiency of the equipment is improved.

Description

Technical Field

[0001] The present application relates to the field of computer technology, and more specifically, to a method and device for improving the wireless charging efficiency of an implantable medical device. Background Art

[0002] The wireless charging system for rechargeable implantable medical devices consists of two parts: an external device and an internal device. The system using electromagnetic induction wireless charging technology transmits wireless energy through the coupling of two air coils. For rechargeable implantable medical devices, since such devices are usually very small and are developing towards a trend of getting smaller and smaller, the internal coil used to receive wireless charging energy is also very small, and its maximum size is limited by the size and shape of such devices. The size of the external charging coil is usually larger, so the coupling coefficient between the internal coil and the external coil is very small. And the coupling coefficient of the two air coils is very sensitive to changes in the distance between the coils.

[0003] The distance between the transmitting coil and the receiving coil is a very demanding factor that restricts the application of wireless charging products. Usually, the acceptable charging distance of wireless charging products is very small. For example, mobile phones, smart watches, electric toothbrushes, etc. basically place the receiving end close to the transmitting end, and the charging distance is only a few millimeters.

[0004] Implantable medical devices usually need to be implanted under the skin, fat layer or even muscle tissue, so the distance from the external transmitting coil may vary from a few millimeters to a few centimeters. After such implantable medical devices are implanted in the patient's body, they may shift or tilt over time, or some patients may gain weight and the depth of the implantation in the skin may increase, causing the wireless charging distance of the device to increase, making it impossible for the external device to wirelessly charge the internal device or the charging efficiency to be low. Summary of the invention

[0005] The main purpose of the present application is to provide a method and device for improving the wireless charging efficiency of implantable medical devices, so as to solve the problem that external devices cannot wirelessly charge internal devices or the charging efficiency is low.

[0006] In order to achieve the above objectives, in a first aspect, the present application provides a method for improving the wireless charging efficiency of an implantable medical device, comprising:

[0007] Obtaining an initial operating frequency of an implantable medical device, wherein the implantable medical device includes an in vitro device and an in vivo device;

[0008] Obtaining an equivalent impedance of an external device, wherein the equivalent impedance is obtained by equivalently comparing the internal device to the external device;

[0009] The initial operating frequency is adjusted according to the equivalent impedance to determine the target operating frequency and target input voltage of the implantable medical device.

[0010] In some implementations, adjusting the initial operating frequency according to the equivalent impedance to determine a target operating frequency and a target input voltage of the implantable medical device includes:

[0011] Determine whether the equivalent impedance increases and obtain a determination result;

[0012] Based on the determination result, a target operating frequency and a target input voltage of the implantable medical device are determined.

[0013] In some implementations, determining a target operating frequency and a target input voltage of the implantable medical device based on the determination result includes:

[0014] If the equivalent impedance increases, the initial operating frequency is increased or decreased to obtain the adjusted operating frequency;

[0015] According to the adjusted operating frequency, a target operating frequency and a target input voltage of the implantable medical device are determined.

[0016] In some implementations, determining a target operating frequency and a target input voltage of the implantable medical device according to the adjusted operating frequency includes:

[0017] The initial input voltage is adjusted based on the adjusted operating frequency until the charging coil of the in-vivo device reaches a preset threshold, thereby obtaining a target operating frequency and a target input voltage.

[0018] In some implementations, determining a target operating frequency and a target input voltage of the implantable medical device based on the determination result includes:

[0019] If the determination result is no, the initial operating frequency is used as the target operating frequency, and the initial input voltage is used as the target input voltage.

[0020] In some implementations, increasing or decreasing the initial operating frequency to obtain an adjusted operating frequency includes:

[0021] After increasing the initial operating frequency, if the equivalent impedance increases, the operating frequency of the previous state is used as the adjusted operating frequency;

[0022] After reducing the initial operating frequency, if the equivalent impedance increases, the initial operating frequency is used as the adjusted operating frequency.

[0023] In some implementations, the method of increasing or decreasing the initial operating frequency includes at least a fixed step adjustment method, a non-fixed step adjustment method, or a table lookup adjustment method.

[0024] In some implementations, the method of adjusting the initial operating frequency according to the equivalent impedance at least includes a method of detecting a charging coil of an external device or an internal device, and a method of detecting a DC input current.

[0025] In some implementations, the initial operating frequency may be the resonant frequency of the charging coil and the resonant capacitor of the in-vivo device, the optimal operating frequency in the current charging state, or the optimal operating frequency determined according to a preset value.

[0026] In a second aspect, an embodiment of the present invention provides an implantable medical device, including: an in vitro device and an in vivo device, for executing the above method.

[0027] The present invention dynamically adjusts the operating frequency and input voltage of the external device according to the size of the equivalent impedance, limits the size of the charging current of the charging coil of the external device, and reduces the charging coil loss of the external device and the related loss of the transmitting circuit. At the same time, the loss of the charging coil of the internal device and the eddy current loss on the metal shell of the internal device are reduced, and the temperature rise of the internal device is reduced. Then, as the charging distance changes, the device always works at the highest efficiency point, so as to improve the wireless charging efficiency of the device. BRIEF DESCRIPTION OF THE DRAWINGS

[0028] The drawings constituting a part of this application are used to provide a further understanding of this application, so that other features, purposes and advantages of this application become more obvious. The schematic embodiment drawings and their descriptions of this application are used to explain this application and do not constitute an improper limitation on this application. In the drawings:

[0029] Figure 1 is a flow chart of a method for improving wireless charging efficiency of an implantable medical device provided by an embodiment of the present invention;

[0030] Figure 2 is a circuit schematic diagram of an implantable medical device provided by an embodiment of the present invention;

[0031] Figure 3 is a circuit schematic diagram of another implantable medical device provided by an embodiment of the present invention;

[0032] Figure 4 is a schematic diagram of the relationship between the coupling coefficient and the coil distance provided by an embodiment of the present invention;

[0033] Figure 5 is a circuit schematic diagram of another implantable medical device provided by an embodiment of the present invention;

[0034] Figure 6 is a schematic diagram of the relationship between the equivalent impedance and the operating frequency provided by an embodiment of the present invention;

[0035] Figure 7is a flowchart of another method for improving wireless charging efficiency of an implantable medical device provided by an embodiment of the present invention;

[0036] Figure 8 It is a flow chart of an implementation of a method for determining a target operating frequency and a target input voltage of an implantable medical device according to equivalent impedance provided by an embodiment of the present invention. DETAILED DESCRIPTION

[0037] In order to make the purpose, technical solution and advantages of the embodiments of the present invention clearer, the technical solution in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0038] The terms "first", "second", "third", "fourth", etc. (if any) in the specification and claims of the present invention and the above drawings are used to distinguish similar objects, and are not necessarily used to describe a specific order or sequence. It should be understood that the numbers used in this way can be interchanged where appropriate, so that the embodiments of the present invention described herein can be implemented in sequences other than those illustrated or described herein.

[0039] It should be understood that in various embodiments of the present invention, the size of the sequence number of each process does not mean the order of execution. The execution order of each process should be determined by its function and internal logic, and should not constitute any limitation on the implementation process of the embodiments of the present invention.

[0040] It should be understood that in the present invention, "including" and "having" and any variations thereof are intended to cover non-exclusive inclusions. For example, a process, method, system, product or apparatus comprising a series of steps or units is not necessarily limited to those steps or units explicitly listed, but may include other steps or units not explicitly listed or inherent to these processes, methods, products or apparatuses.

[0041] It should be understood that in the present invention, "plurality" refers to two or more than two. "And / or" is merely a description of the association relationship of associated objects, indicating that three relationships may exist. For example, and / or B can represent: A exists alone, A and B exist at the same time, and B exists alone. The character " / " generally indicates that the objects associated before and after are in an "or" relationship. "Contains A, B and C", "Contains A, B, C" means that A, B, and C are all included, "Contains A, B or C" means that one of A, B, and C is included, and "Contains A, B and / or C" means that any one, any two, or any three of A, B, and C are included.

[0042] It should be understood that in the present invention, "B corresponding to A", "B corresponding to A", "A corresponds to B" or "B corresponds to A" means that B is associated with A and B can be determined based on A. Determining B based on A does not mean determining B based only on A, but B can also be determined based on A and / or other information. A and B match when the similarity between A and B is greater than or equal to a preset threshold.

[0043] Depending on the context, "if" as used herein may be interpreted as "when" or "when" or "in response to determining" or "in response to detecting."

[0044] The technical solution of the present invention is described in detail with specific embodiments below. The following specific embodiments can be combined with each other, and the same or similar concepts or processes may not be described in detail in some embodiments.

[0045] In order to make the purpose, technical solutions and advantages of the present invention clearer, the relevant technical terms of the present invention are first explained as follows:

[0046] In one embodiment, if Figure 1 As shown, the present invention provides a method for improving the wireless charging efficiency of an implantable medical device, comprising the following steps:

[0047] Step S101: obtaining an initial operating frequency of an implantable medical device.

[0048] Among them, implantable medical devices include external devices and internal devices. Figure 2 As shown, Figure 2 1 indicates an external device, 2 and 3 indicate internal devices, and 2 and 3 indicate two optional methods. L1 and L2 are charging coils for the external device and the internal device, respectively.

[0049] Due to the low efficiency of electromagnetic induction wireless charging, the charging coil L1 of the external device usually needs to pass a large current i1 to provide a strong magnetic field so that the charging coil L2 of the internal device can obtain a sufficiently high induced voltage. However, excessive external coil current will produce a large loss, resulting in energy waste and heat generation. In addition, excessive electromagnetic fields can cause overheating and damage to skin tissue.

[0050] Among them, the initial operating frequency can be the resonant frequency of the charging coil and the resonant capacitor of the in-vivo device (i.e., the resonant frequency of the charging coil L2 and the resonant capacitor C2 of the in-vivo device), the optimal operating frequency in the charging state, that is, at the beginning of each charging, a frequency calibration is performed to obtain the optimal operating frequency in the current charging state or the optimal operating frequency determined according to the preset value, that is, an optimal operating frequency is obtained by using a table lookup method, and this optimal operating frequency is a predetermined value obtained according to the test or simulation results at a specific relative position. In order to obtain a higher charging efficiency, the operating frequency of the implantable medical device refers to the oscillation frequency of the charging coil L1 of the in-vivo device, and the initial operating frequency is usually set to the resonant frequency of the charging coil L2 and the resonant capacitor C2.

[0051] Step S102: Obtaining the equivalent impedance of the extracorporeal device.

[0052] In-vivo devices are usually composed of PCBA, rechargeable battery, charging coil, metal casing such as titanium or titanium alloy, etc. In the induced magnetic field environment generated by the charging coil L1, all metal components will generate eddy currents and affect the equivalent inductance of the charging coil L2. The magnitude of this effect is different when the distance between the charging coil L2 and the charging coil L1 changes or when the degree of axial deviation between the charging coil L2 and the charging coil L1 changes, and when the implanted device is tilted. As long as the relative position of the charging coil L1 and the charging coil L2 changes, the equivalent inductance of the charging coil L2 will change. For example, as the distance between the coils increases, the equivalent inductance of the charging coil L2 will decrease.

[0053] Therefore, the present invention proposes a non-fixed operating frequency mode, which dynamically tracks the size of the equivalent converted impedance Zin as the charging distance changes, so that the operating frequency changes within a certain range.

[0054] The equivalent impedance is obtained by equivalently comparing the internal device to the external device. The internal device is regarded as a whole and is considered as the equivalent load of the external device. The size of this equivalent load is Zs. This equivalent load is converted into an equivalent impedance Zr on the external coil transmitting loop, as shown in Figure 3 As shown, the mathematical expression of Zr is:

[0055] Zr=w2M 2 / Zs.

[0056] Where, w = 2πf, f is the operating frequency, w is the operating angular frequency, k is the coupling coefficient, and M is the mutual inductance of L1 and L2.

[0057] The size of this equivalent reduced impedance is strongly related to the coupling coefficient between the two coils and the operating frequency. The coupling coefficient is very sensitive to the relative position relationship between the coils, including changes in the distance between the coils and changes in the degree of deflection. Figure 4 This is the relationship curve between the coupling coefficient k and the coil distance.

[0058] Therefore, if Figure 5 As shown, the total equivalent reduced impedance of the in vitro device transmitting circuit is Zin=Rs+R1+jwL1+Zr, where jwL1 refers to the inductive reactance of L1, R1 refers to the impedance of L1, R1+jwL1 refers to the reactance of L1, and Rs refers to the source impedance. Figure 6 This is the relationship curve between the equivalent reduced impedance Zin and the operating frequency f.

[0059] Step S103: adjusting the initial operating frequency according to the equivalent impedance to determine the target operating frequency and target input voltage of the implantable medical device.

[0060] The initial operating frequency is adjusted according to the equivalent impedance to determine the target operating frequency and target input voltage of the implantable medical device. It is necessary to first determine whether the equivalent impedance increases, obtain a judgment result, and then determine the target operating frequency and target input voltage of the implantable medical device based on the judgment result.

[0061] Among them, based on the judgment result, the target operating frequency and target input voltage of the implantable medical device are determined, including two situations: the first is that if the equivalent impedance increases, the initial operating frequency is increased or decreased to obtain the adjusted operating frequency, and the target operating frequency and target input voltage of the implantable medical device are determined according to the adjusted operating frequency. Among them, the target operating frequency and target input voltage of the implantable medical device are determined according to the adjusted operating frequency, including: adjusting the initial input voltage based on the adjusted operating frequency until the charging coil of the in-vivo device reaches a preset threshold, and obtaining the target operating frequency and target input voltage. The second is that if the judgment result is no, the initial operating frequency is used as the target operating frequency, and the initial input voltage is used as the target input voltage.

[0062] Specific as Figure 7As shown, first set the initial operating frequency of the device, and then adjust the operating frequency according to the size of the equivalent converted impedance Zin. If the impedance increases, increase or decrease the operating frequency, and then adjust the input voltage according to the adjusted frequency so that the induced voltage of the charging coil L2 of the in-vivo device reaches the set value. After the induced voltage of the charging coil L2 of the in-vivo device reaches the set value, the current operating frequency is used as the target operating frequency and input voltage to charge the in-vivo device, and the change of the equivalent converted impedance Zin is monitored in real time. If the impedance does not increase, the current operating frequency and input voltage will be maintained for stable charging, and the change of the equivalent converted impedance Zin will be monitored in real time.

[0063] Among them, the method of adjusting the initial operating frequency according to the equivalent impedance (equivalent converted impedance Zin) at least includes the method of detecting the external device, such as detecting the current or voltage of the charging coil L1 of the external device or detecting the magnitude of the DC input current; or detecting the charging coil of the internal device, such as detecting the induced voltage or current of the charging coil L2 of the internal device, and then feeding back to the external device controller through PPM or Bluetooth communication. The external device controller determines whether the equivalent converted impedance Zin of the internal device increases according to the value and change law of the parameter detected or transmitted by the internal device; or other detection or judgment methods indirectly detect the magnitude of the equivalent converted impedance Zin.

[0064] like Figure 8 As shown, in one embodiment, the increasing or decreasing the operating frequency in the above operation may specifically include the following operations: first, the operating frequency may be increased or decreased (in this embodiment, the operating frequency is increased, which may be replaced by decreasing the operating frequency), and firstly, it is determined whether the equivalent reduced impedance Zin increases;

[0065] If it is determined that Zin increases for the first time, the operating frequency is reduced, and it is determined again whether Zin increases. If it is determined that Zin increases again, the operating frequency of the previous state is maintained. If it is determined that Zin does not increase again, the operating frequency continues to be reduced until Zin increases.

[0066] If it is determined for the first time that Zin has not increased, the operating frequency will continue to increase, and it will be determined again whether Zin has increased. If it is determined again that Zin has increased, the operating frequency of the previous state will be maintained. If it is determined again that Zin has not increased, the operating frequency will continue to increase until Zin increases.

[0067] In this embodiment, the purpose of first judging whether the equivalent reduced impedance Zin increases is to determine whether the initial adjustment direction (increase or decrease) of the operating frequency is correct. If Zin increases, it means that the adjustment direction is incorrect, and the subsequent adjustment direction is changed to reverse adjustment (increase at the beginning and then change to decrease later); if Zin does not increase, it means that the initial adjustment direction is correct, then continue to adjust in the current direction (increase at the beginning and then continue to increase) until the point where Zin is the smallest (inflection point, Zin first decreases and then increases), the point where Zin is the smallest corresponds to the previous state, so the frequency of the previous state is used as the target frequency.

[0068] like Figure 6 As shown, for example, when the distance between the coils increases, from position 1 to position 2, the equivalent reduced impedance curve shifts rightward from position 1 to position 2. In the working state of position 1, the working frequency of the external device is f1, and the input voltage is V1. At this time, the charging efficiency is the highest, and f1 is the resonant frequency of position 1. In the next state, the coil distance changes to position 2. If the working frequency remains unchanged at f1, the equivalent reduced impedance Zin becomes larger and capacitive, and the vector size of Zin |Zin| becomes larger. Under the current input voltage V1, the current of the charging coil L1 of the external device decreases, and the induced voltage of the charging coil L2 of the internal device decreases.

[0069] In order to make the coil L2 of the in-vivo device generate enough induced voltage to maintain the energy for charging the battery of the in-vivo device, it is usually necessary to increase the input voltage, but this will generate additional power consumption. When the coil changes to position 2, the method of the present invention first increases the operating frequency to a new resonant frequency f2, and then adjusts the input voltage so that the induced voltage of the charging coil L2 of the in-vivo device reaches the set value. In this way, the input voltage required for the new state is lower than that of the traditional fixed frequency charging method. Similarly, if the coil distance changes from position 2 to position 1, the operating frequency is reduced, so that the operating frequency is reduced from f2 to f1.

[0070] Specific parameter adjustment example: Set the initial operating frequency to 10kHz. Assuming that the coil position is position 1, first set the initial input voltage to 4.5V. According to the monitored Zin size, adjust the operating frequency to f1=10.2kHz to make the system work at the operating point Zin1 with the minimum Zin. Then adjust the input voltage to make the induced voltage reach the set value range. At this time, the input voltage Vin1 is 4.65V and the charging efficiency is 6.2%. Maintain the current operating frequency and input voltage for stable charging, and monitor the changes in the equivalent converted impedance Zin in real time.

[0071] When the coil position changes to position 2, Zin increases to Zin2'. First, increase the operating frequency, for example, gradually increase the operating frequency according to a fixed step of 0.1kHz. When it increases to f2 = 11.6kHz, the system works at the new operating point Zin2 where Zin is the minimum. Then adjust the input voltage to make the induced voltage reach the set value range. At this time, the input voltage Vin2 is 4.79 and the charging efficiency is 16.7%.

[0072] The traditional method has a fixed operating frequency, for example, a fixed operating frequency of 10.2kHz. When in position 1, the required input voltage is 4.65V, and the charging efficiency is 6.2%. When in position 2, the required input voltage is 4.98V, and the charging efficiency is 15.99%. The charging efficiency is 0.71% lower than the scheme described in this article. Among them, adjusting the input voltage includes increasing the input voltage or decreasing the input voltage. Including different implementation methods, according to the required response speed and accuracy, or according to the size of the change in the equivalent converted impedance Zin, such as fixed step adjustment, non-fixed step adjustment, or table lookup adjustment, etc.

[0073] If the induced voltage of the charging coil L2 of the in-vivo device reaches the set value, the current operating frequency and input voltage are maintained to charge the in-vivo device, and the change of the equivalent reduced impedance Zin is read at a certain time interval. When the change of the equivalent reduced impedance Zin is detected, the operating frequency is adjusted again to adjust it to the resonance point of the new position. Among them, the induced voltage reaches the set value means that the induced voltage of the in-vivo coil is usually within an acceptable range.

[0074] The method of increasing or decreasing the initial operating frequency at least includes a fixed step adjustment method, a non-fixed step adjustment method or a table lookup adjustment method, and the purpose is to adjust it to the resonant frequency point at a new position.

[0075] The present invention dynamically adjusts the operating frequency (resonant frequency) and input voltage of the external device according to the size of the equivalent impedance, limits the size of the charging current of the charging coil of the external device, and reduces the charging coil loss of the external device and the related loss of the transmitting circuit. At the same time, the loss of the charging coil of the internal device and the eddy current loss on the metal shell of the internal device are reduced, and the temperature rise of the internal device is reduced. Then, as the charging distance changes, the device always works at the highest efficiency point to improve the wireless charging efficiency of the device.

[0076] It should be understood that the order of execution of the steps in the above embodiment does not necessarily mean the order of execution. The execution order of each process should be determined by its function and internal logic, and should not constitute any limitation on the implementation process of the embodiment of the present invention.

[0077] Those skilled in the art will appreciate that embodiments of the present invention may be provided as methods, systems, or computer program products. Therefore, the present invention may take the form of a complete hardware embodiment, a complete software embodiment, or an embodiment combining software and hardware. Moreover, the present invention may take the form of a computer program product implemented on one or more computer-usable storage media (including but not limited to disk storage, CD-ROM, optical storage, etc.) containing computer-usable program code.

[0078] The present invention is described with reference to flowcharts and / or block diagrams of methods, devices (systems), and computer program products according to embodiments of the present invention. It should be understood that each process and / or block in the flowchart and / or block diagram, as well as the combination of processes and / or blocks in the flowchart and / or block diagram, can be implemented by computer program instructions. These computer program instructions can be provided to a processor of a general-purpose computer, a special-purpose computer, an embedded processor, or other programmable data processing device to produce a machine, so that the instructions executed by the processor of the computer or other programmable data processing device generate instructions for implementing the processes in the flowchart and / or block diagram. Figure 1 A process or multiple processes and / or boxes Figure 1 A device that provides the functions specified in a block or multiple blocks.

[0079] These computer program instructions may also be stored in a computer-readable memory capable of directing a computer or other programmable data processing device to operate in a specific manner, so that the instructions stored in the computer-readable memory produce an article of manufacture comprising an instruction device, which implements the process Figure 1 A process or multiple processes and / or boxes Figure 1 A function specified in one or more boxes.

[0080] These computer program instructions can also be loaded onto a computer or other programmable data processing device so that a series of operating steps are executed on the computer or other programmable device to produce a computer-implemented process, thereby providing instructions for implementing the process. Figure 1 A process or multiple processes and / or boxes Figure 1 A step that specifies a function in one or more boxes.

[0081] Obviously, the above embodiments are merely examples for the purpose of clear explanation, and are not intended to limit the implementation methods. For those skilled in the art, other different forms of changes or modifications can be made based on the above description. It is not necessary and impossible to list all the implementation methods here. The obvious changes or modifications derived therefrom are still within the scope of protection of the invention.

Claims

1. A method for improving wireless charging efficiency of an implantable medical device, characterized in that: include: Acquiring an initial operating frequency of an implantable medical device, wherein the implantable medical device includes an external device and an internal device; Obtaining an equivalent impedance of the external device, wherein the equivalent impedance is obtained by equivalently calculating the internal device; The initial operating frequency is adjusted according to the equivalent impedance to determine a target operating frequency and a target input voltage of the implantable medical device.

2. The method for improving wireless charging efficiency of an implantable medical device according to claim 1, characterized in that: The step of adjusting the initial operating frequency according to the equivalent impedance to determine a target operating frequency and a target input voltage of the implantable medical device includes: Determine whether the equivalent impedance increases, and obtain a determination result; Based on the determination result, a target operating frequency and a target input voltage of the implantable medical device are determined.

3. The method for improving wireless charging efficiency of an implantable medical device as claimed in claim 2, characterized in that: Determining a target operating frequency and a target input voltage of the implantable medical device based on the judgment result includes: If the equivalent impedance increases, the initial operating frequency is increased or decreased to obtain an adjusted operating frequency; According to the adjusted operating frequency, a target operating frequency and a target input voltage of the implantable medical device are determined.

4. The method for improving wireless charging efficiency of an implantable medical device as claimed in claim 3, characterized in that: Determining a target operating frequency and a target input voltage of the implantable medical device according to the adjusted operating frequency includes: The initial input voltage is adjusted based on the adjusted operating frequency until the induced voltage of the charging coil of the in-vivo device reaches a preset threshold, thereby obtaining the target operating frequency and the target input voltage.

5. The method for improving wireless charging efficiency of an implantable medical device as claimed in claim 2, characterized in that: Determining a target operating frequency and a target input voltage of the implantable medical device based on the judgment result includes: If the determination result is no, the initial operating frequency is used as the target operating frequency, and the initial input voltage is used as the target input voltage.

6. The method for improving wireless charging efficiency of an implantable medical device as claimed in claim 3, characterized in that: The increasing or decreasing the initial operating frequency to obtain an adjusted operating frequency includes: After increasing the initial operating frequency, if the equivalent impedance increases, the operating frequency of the previous state is used as the adjusted operating frequency; After reducing the initial operating frequency, if the equivalent impedance increases, the initial operating frequency is used as the adjusted operating frequency.

7. The method for improving wireless charging efficiency of an implantable medical device as claimed in claim 3, characterized in that: The method of increasing or decreasing the initial operating frequency at least includes a fixed step adjustment method, a non-fixed step adjustment method or a table lookup adjustment method.

8. The method for improving wireless charging efficiency of an implantable medical device according to any one of claims 1 to 7, characterized in that: The method of adjusting the initial operating frequency according to the equivalent impedance at least includes a method of detecting a charging coil of an external device or an internal device, and a method of detecting a DC input current.

9. The method for improving wireless charging efficiency of an implantable medical device according to any one of claims 1 to 7, characterized in that: The initial operating frequency may be a resonant frequency of a charging coil and a resonant capacitor of the in-vivo device, an optimal operating frequency in a current charging state, or an optimal operating frequency determined according to a preset value.

10. An implantable medical device, characterized in that: include: An in vitro device and an in vivo device for performing the method according to any one of claims 1 to 9.

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