Soothing and repairing essence lotion containing rhizoma corydalis root extract and preparation method of soothing and repairing essence lotion

Abstract

The invention discloses soothing and repairing essence lotion containing rhizoma corydalis root extract and a preparation method of the soothing and repairing essence lotion. The essence lotion is prepared from a component A, a component B, a component C and a component D. The component A is prepared from, by weight, 1.01%-3.04% of humectants, 0.23%-0.48% of thickening agents, 0.05%-0.20% of beta-glucan and 70.00%-77.00% of deionized water. The component B is prepared from the following raw materials in percentage by weight: 0.50 to 1.50 percent of butyrospermum parkii butter, 1.00 to 3.00 percent of tridecyl trimellitate, 0.15 to 0.36 percent of polydimethylsiloxane, 0.60 to 0.90 percent of glycerol tri (ethylhexoic acid) ester, 0.43 to 0.58 percent of simmondsia chinensis seed oil and 0.02 to 0.06 percent of phytosterol oleate; the component C is prepared from the following components in percentage by weight: 1.10 to 2.50 percent of an emulsifying agent, 0.40 to 0.60 percent of an antioxidant, 3.00 to 5.00 percent of butanediol, 0.15 to 0.45 percent of fibronectin, 0.30 to 0.70 percent of 1, 2-hexanediol and 10 to 13 percent of deionized water; and the component D comprises the following components in percentage by weight: 0.03%-0.10% of a neutralizing agent and 1.50%-3.50% of an anti-allergic agent. According to the invention, the rhizoma corydalis root extract is used as a main active component and is prepared into the essence lotion with the effects of relieving skin and repairing sensitive skin together with other auxiliary materials.

Description

Technical Field

[0001] The invention relates to the technical field of cosmetics, and in particular to a soothing and repairing essence lotion containing a Corydalis yanhusuo root extract and a preparation method thereof. Background Art

[0002] In recent years, with the changes in people's dietary structure, the increasing severity of air pollution, and the increase in people's life and work pressure, the number of allergy patients has increased dramatically, and skin sensitivity has become a social problem that affects human health. According to incomplete statistics, more and more people in the world feel that they have sensitive skin, of which 38% are men and 61% are women. Therefore, providing a soothing and repairing essence lotion that can be used for sensitive skin, improving the allergy problem of sensitive skin, and repairing and maintaining the skin barrier are technical problems that need to be solved at present.

[0003] Corydalis yanhusuo is a plant of the genus Corydalis of the family Papaveraceae. Corydalis yanhusuo root extract has the effects of calming and anti-inflammatory, soothing and anti-allergic, and reducing redness and itching. When combined with various ingredients in the soothing and repairing essence lotion, it can promote skin barrier repair and relieve skin inflammation and sensitive reactions. Summary of the invention

[0004] The purpose of the present invention is to provide a soothing and repairing essence lotion containing Corydalis root extract and a preparation method thereof, which improves dryness, roughness and tightness of the skin by combining fibronectin, jojoba seed oil, β-glucan, sodium hyaluronate and other ingredients; adding Corydalis root extract can enhance the skin barrier function of sensitive skin, soothe damaged skin, relieve skin redness, itching and other problems, and help the skin recover to its best state.

[0005] The present invention also provides the soothing and repairing essence lotion containing the Corydalis root extract and a preparation method thereof.

[0006] According to one aspect of the present invention, a soothing and repairing essence lotion containing a Corydalis root extract is provided, and the essence lotion comprises, by mass percentage:

[0007] Component A: humectant 1.01-3.04%, thickener 0.23-0.48%, β-glucan 0.05-0.20%, deionized water 70.00-77.00%;

[0008] Component B: avocado butter 0.50-1.50%, tridecyl trimellitate 1.00-3.00%, polydimethylsiloxane 0.15-0.36%, triethylhexanoin 0.60-0.90%, jojoba seed oil 0.43-0.58%, phytosteryl oleate 0.02-0.06%;

[0009] Component C: emulsifier 1.10-2.50%, antioxidant 0.40-0.60%, butanediol 3.00%-5.00%, fibronectin 0.15-0.45%, 1,2-hexanediol 0.30-0.70%, deionized water 10-13%;

[0010] Component D: neutralizer 0.03-0.10%, anti-allergic agent 1.50%-3.50%.

[0011] The anti-allergic agent is CTR50, which is composed of the following mass percentages: 2.00-10.00% of Corydalis root extract, 70.00-85.00% of butylene glycol, 0.50-4.00% of citric acid, and 5.00-25.00% of dimethyl isosorbide.

[0012] Preferably, the preparation method of the Corydalis root extract comprises: placing Corydalis root crude powder in a flask, adding 60% ethanol, soaking and refluxing for 1 hour, repeating the extraction three times, combining the three extracts and evaporating and concentrating them until viscous, and vacuum drying to obtain the Corydalis root extract.

[0013] Preferably, the moisturizing agent is composed of sodium hyaluronate and panthenol, and the percentage based on the total weight of the soothing and repairing essence milk is: 0.01-0.04% sodium hyaluronate, 1.00-3.00% panthenol.

[0014] Preferably, the thickener is composed of acacia gum, xanthan gum and ammonium acryloyldimethyltaurate / VP copolymer, and the percentage based on the total weight of the soothing and repairing essence milk is: acacia gum 0.02-0.05%, xanthan gum 0.01-0.03%, ammonium acryloyldimethyltaurate / VP copolymer 0.20-0.40%.

[0015] Preferably, the emulsifier is composed of hydrogenated phosphatidylcholine, cetearyl olivate and sorbitan olivate, and the percentages based on the total weight of the soothing and repairing essence milk are: 0.10-0.20% hydrogenated phosphatidylcholine, 0.50-1.50% cetearyl olivate, and 0.50-0.80% sorbitan olivate.

[0016] Preferably, the antioxidant is p-hydroxyacetophenone, and the percentage of p-hydroxyacetophenone based on the total weight of the soothing and repairing essence milk is: 0.40-0.60% p-hydroxyacetophenone.

[0017] Preferably, the neutralizing agent is arginine, and the percentage of arginine based on the total weight of the soothing and repairing essence milk is: 0.03-0.10%.

[0018] The second technical solution adopted by the present invention is: a soothing and repairing essence lotion containing Corydalis root extract and a preparation method thereof, comprising the following preparation steps:

[0019] (1) Pre-dispersing the thickener in component A in deionized water, adding the humectant and β-glucan, heating to 85-90° C., and homogenizing for 2-3 minutes until all dissolved, to obtain a mixture A;

[0020] (2) heating avocado butter, tridecyl trimellitate, polydimethylsiloxane, triethylhexanoin, jojoba seed oil, and phytosteryl oleate in component B to 85-90° C. and stirring slowly until all of them are dissolved to obtain a uniform oily mixture B;

[0021] (3) Pour mixed material A into mixed material B, add emulsifier at the same time, homogenize at high speed for 2 to 3 minutes, stir and disperse evenly, and vacuum and keep warm for 20 minutes to defoam;

[0022] (4) When the temperature drops to 45-65° C., add p-hydroxyacetophenone dissolved in butylene glycol, and then add other materials of component C dissolved in deionized water, and stir evenly;

[0023] (5) When the temperature drops below 45°C, add the materials in component D, stir evenly and then discharge the materials to obtain the finished product.

[0024] The beneficial effects of the present invention are as follows: the essence milk prepared by the present invention is rich in a variety of active ingredients such as avocado tree fat, β-glucan, sodium hyaluronate, fibronectin, etc., which can soften the skin, lock skin moisture, moisturize the skin, and accelerate cell proliferation and metabolism; combined with the Corydalis root extract, the essence milk has soothing and repairing effects. BRIEF DESCRIPTION OF THE DRAWINGS

[0025] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative labor.

[0026] Figure 1 It is a soothing and repairing essence lotion that is effective for allergic dermatitis.

[0027] Figure 2 To study the effect of soothing and repairing essence lotion on acne vulgaris. DETAILED DESCRIPTION

[0028] The technical solutions in the embodiments of the present invention are described clearly and completely below. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of them. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0029] Embodiment 1:

[0030] Provided are a soothing and repairing essence lotion containing a Corydalis root extract and a preparation method thereof. The soothing and repairing essence lotion comprises, by mass percentage:

[0031] Component A: Sodium hyaluronate 0.03%, panthenol 1.50%, gum arabic 0.04%, xanthan gum 0.02%, ammonium acryloyldimethyltaurate / VP copolymer 0.32%, β-glucan 0.10%, deionized water 73.34%;

[0032] Component B: avocado butter 1.00%, tridecyl trimellitate 2.00%, dimethicone 0.20%, triethylhexanoin 0.80%, jojoba seed oil 0.51%, phytosteryl oleate 0.06%;

[0033] Component C: hydrogenated phosphatidylcholine 0.13%, cetearyl olivate 1.02%, sorbitan olivate 0.68%, p-hydroxyacetophenone 0.50%, butylene glycol 4.00%, fibronectin 0.20%, 1,2-hexanediol 0.50%, deionized water 11.00%;

[0034] Component D: Arginine 0.05%, CTR50 2.00%.

[0035] The preparation method compatible with the above embodiment is carried out according to the following steps:

[0036] (1) Pre-dispersing the thickener in component A in deionized water, then adding sodium hyaluronate, panthenol and β-glucan, heating to 85-90° C., and homogenizing for 2-3 minutes until all dissolved to obtain a mixture A;

[0037] (2) heating avocado butter, tridecyl trimellitate, polydimethylsiloxane, triethylhexanoin, jojoba seed oil, and phytosteryl oleate in component B to 85-90° C. and stirring slowly until all of them are dissolved to obtain a uniform oily mixture B;

[0038] (3) Pour mixed material A into mixed material B, add emulsifier at the same time, homogenize at high speed for 2 to 3 minutes, stir and disperse evenly, and vacuum and keep warm for 20 minutes to defoam;

[0039] (4) When the temperature drops to 45-65° C., add p-hydroxyacetophenone dissolved in butylene glycol, and then add other materials of component C dissolved in deionized water, and stir evenly;

[0040] (5) When the temperature drops below 45°C, add the materials in component D, stir evenly and then discharge the materials to obtain the finished product.

[0041] Embodiment 2:

[0042] Provided are a soothing and repairing essence lotion containing Corydalis root extract and a preparation method thereof, which is different from Example 1 in that: the added amount of p-hydroxyacetophenone in component C is 0.70%, the added amount of CTR50 in component D is 2.20%, and deionized water is reduced so that the total amount of each substance is 100%.

[0043] The preparation steps of the above embodiment are the same as those of embodiment 1.

[0044] Embodiment 3:

[0045] Provided are a soothing and repairing essence lotion containing Corydalis root extract and a preparation method thereof, which is different from Example 1 in that: the added amount of p-hydroxyacetophenone in component C is 0.90%, the added amount of CTR50 in component D is 2.40%, and deionized water is reduced so that the total amount of each substance is 100%.

[0046] The preparation steps of the above embodiment are the same as those of embodiment 1.

[0047] Embodiment 4:

[0048] Provided are a soothing and repairing essence lotion containing Corydalis root extract and a preparation method thereof, which is different from Example 1 in that: the added amount of p-hydroxyacetophenone in component C is 1.10%, the added amount of CTR50 in component D is 2.60%, and deionized water is reduced so that the total amount of each substance is 100%.

[0049] The preparation steps of the above embodiment are the same as those of embodiment 1.

[0050] The effects of the embodiments of the present invention are described below in conjunction with experimental data.

[0051] Test Example 1: Allergic Dermatitis Application

[0052] The soothing and repairing essence lotion prepared in Example 1 was evaluated for its rapid redness and itching fading effect. 35 subjects with healthy skin, no history of skin diseases and allergies were randomly selected, with an average age of 35 years old. The facial changes of the subjects were detected using VISIA skin image analyzer. The specific results are shown in Figure 1 .

[0053] Experimental results: On the second day of using the soothing and repairing essence, the redness and inflammation on the subjects' cheeks were significantly reduced.

[0054] Test Example 2: Application of the product in acne vulgaris

[0055] Patients with facial redness and acne were selected and smeared with isotretinoin and the soothing and repairing essence lotion prepared in Example 1 twice a day. The facial changes of the subjects were detected using the VISIA skin image analyzer. The specific results are shown in Figure 2 .

[0056] Experimental results: On the 21st day of using isotretinoin in combination with the soothing and repairing essence lotion, the patient's facial skin inflammation improved significantly, redness and swelling subsided, and acne was alleviated.

[0057] Test Example 3: Evaluation of the efficacy of the skin barrier

[0058] The barrier repair function of the soothing repair essence prepared in Example 1 was evaluated. Referring to the industry standard QB / T 4256-2011, the Tewameter TM300 (skin water loss TEWL tester) was used to measure the loss of skin surface water of women aged 18 to 55 with dry and rough facial skin before and after using the soothing repair essence. The average value of skin water loss TEWL is shown in Table 1.

[0059] Table 3 Average values ​​of skin water loss TEWL

[0060]

[0061] Table 1 shows that compared with before using the soothing repair essence (i.e., D0), after continuous use of the essence for 28 days, the transepidermal water loss of the skin showed a downward trend, decreasing by 9.14%, which was extremely significantly different from the D0 group (p < 0.01), indicating that the soothing repair essence containing Corydalis yanhusuo root extract has a good effect in repairing the skin barrier.

[0062] The embodiments of the present invention are described in detail above, but the present invention is not limited to the described embodiments. For those skilled in the art, various changes, modifications, substitutions and variations of these embodiments are made without departing from the principles and spirit of the present invention, and still fall within the protection scope of the present invention.

Claims

1. A soothing and repairing essence lotion containing Corydalis yanhusuo root extract, It is characterized in that The essence milk comprises by mass percentage: Component A: humectant 1.01~3.04%, thickener 0.23~0.48%, β-glucan 0.05~0.20%, deionized water 70.00~77.00%; Component B: avocado butter 0.50-1.50%, tridecyl trimellitate 1.00-3.00%, dimethicone 0.15-0.36%, triethylhexanoin 0.60-0.90%, jojoba seed oil 0.43-0.58%, phytosteryl oleate 0.02-0.06%; Component C: emulsifier 1.10~2.50%, antioxidant 0.40~0.60%, butanediol 3.00%~5.00%, fibronectin 0.15~0.45%, 1,2-hexanediol 0.30~0.70%, deionized water 10~13%; Component D: neutralizer 0.03~0.10%, anti-allergic agent 1.50%~3.50%; Wherein, the anti-allergic agent is CTR50, and the CTR50 is composed of the following mass percentages: 2.00-10.00% of Corydalis yanhusuo root extract, 70.00-85.00% of butylene glycol, 0.50-4.00% of citric acid, and 5.00-25.00% of dimethyl isosorbide.

2. The soothing and repairing essence lotion containing the Corydalis root extract according to claim 1, It is characterized in that The preparation method of the Corydalis root extract comprises: placing the Corydalis root crude powder in a flask, adding 60% ethanol, soaking and then refluxing for extraction for 1 hour, repeating the extraction three times, combining the three extracts, evaporating and concentrating them to a viscous state, and vacuum drying to obtain the Corydalis root extract.

3. The soothing and repairing essence lotion containing the Corydalis root extract according to claim 1, It is characterized in that The moisturizing agent is composed of sodium hyaluronate and panthenol, and is calculated as follows according to the percentage of the total weight of the soothing and repairing essence milk: sodium hyaluronate 0.01-0.04%, panthenol 1.00-3.00%.

4. The soothing and repairing essence lotion containing the Corydalis root extract according to claim 1, It is characterized in that The thickener is composed of acacia gum, xanthan gum and ammonium acryloyldimethyltaurate / VP copolymer, and is calculated as follows based on the percentage of the total weight of the soothing and repairing essence milk: 0.02-0.05% of acacia gum, 0.01-0.03% of xanthan gum, and 0.20-0.40% of ammonium acryloyldimethyltaurate / VP copolymer.

5. The soothing and repairing essence lotion containing the Corydalis root extract according to claim 1, It is characterized in that The emulsifier is composed of hydrogenated phosphatidylcholine, cetearyl olivate and sorbitan olivate, and is calculated as follows based on the percentage of the total weight of the soothing and repairing essence milk: 0.10-0.20% hydrogenated phosphatidylcholine, 0.50-1.50% cetearyl olivate, and 0.50-0.80% sorbitan olivate.

6. The soothing and repairing essence lotion containing the Corydalis root extract according to claim 1, It is characterized in that The antioxidant is p-hydroxyacetophenone, and the percentage of p-hydroxyacetophenone in the total weight of the soothing and repairing essence milk is: 0.40-0.60%.

7. The soothing and repairing essence lotion containing the Corydalis root extract according to claim 1, It is characterized in that The neutralizing agent is arginine, and the percentage of the total weight of the soothing and repairing essence milk is: arginine 0.03-0.10%.

8. The soothing and repairing essence lotion containing Corydalis root extract according to claim 1, It is characterized in that The preparation steps are as follows: (1) Pre-disperse the thickener in component A in deionized water, then add the humectant and β-glucan, heat to 85-90°C, and homogenize for 2-3 minutes until all dissolved to obtain a mixture A; (2) heating the avocado butter, tridecyl trimellitate, polydimethylsiloxane, triethylhexanoin, jojoba seed oil, and phytosteryl oleate in component B to 85-90° C. and stirring slowly until all of them are dissolved to obtain a uniform oily mixture B; (3) Pour mixture A into mixture B and add emulsifier at the same time. Homogenize at high speed for 2-3 minutes, stir and disperse evenly, and vacuum and keep warm for 20 minutes to defoam. (4) When the temperature drops to 45-65°C, add p-hydroxyacetophenone dissolved in butanediol, and then add other materials of component C dissolved in deionized water, and stir evenly; (5) When the temperature drops below 45°C, add the materials in component D, stir evenly and then discharge the materials to obtain the finished product.

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