Preparation process of shiny-leaved yellowhorn tea mixed extract and application of shiny-leaved yellowhorn tea mixed extract in treatment of prostatitis

The preparation of Wenguan Fruit Tea mixed extract through multiple processing techniques solved the problem of low extraction rate of Wenguan Fruit Flower in the treatment of prostatitis, forming non-toxic extracts for the treatment of prostatitis, achieving more efficient extraction of beneficial ingredients and therapeutic effects.

CN119113005APending Publication Date: 2024-12-13HEBEI RUNSHENG AGRI TECH
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Patent Information

Application Number
CN202411250908.8
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-09-06
Publication Date
2024-12-13

AI Technical Summary

Technical Problem

The prior art Chinese saccharin is less used in medical treatment of prostatitis, and the conventional use of the extracting rate of beneficial substances is low.

Method used

The Wenguan Fruit Tea mixed extract is prepared by multiple processing techniques, including preliminary treatment, crushing treatment, centrifugation treatment and final product formation. The extraction rate of beneficial ingredients is improved through the steps of selection, crushing, extraction and drying, and dissolved with ethanol. The agent and aromatic hydrocarbon form a cream-like or viscous powder.

Benefits of technology

It effectively improves the extraction rate of beneficial ingredients in Wenguan Fruit Flower. The prepared Wenguan Fruit Tea mixed extract is not toxic and is suitable for the treatment of prostatitis. It has therapeutic effects when water dissolution is 50-60℃.

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Abstract

The invention discloses a preparation process of a shiny-leaved yellowhorn tea mixed extract and application of the shiny-leaved yellowhorn tea mixed extract in treatment of prostatitis, and belongs to the technical field of shiny-leaved yellowhorn tea preparation processes, the preparation process of the shiny-leaved yellowhorn tea mixed extract and application of the shiny-leaved yellowhorn tea mixed extract in treatment of prostatitis. Carrying out primary treatment; step 2, performing crushing treatment on shiny-leaved yellowhorn flowers, and obtaining extract coarse powder; step 3, carrying out centrifugal treatment on the coarse powder of the extract; and 4, adding the mixture to form a final finished product of the shiny-leaved yellowhorn tea mixed extract. The xanthoceras sorbifolia bunge flower can be used as a raw material, the xanthoceras sorbifolia bunge and tea mixed extract product is finally prepared through multiple times of processing, the extraction rate of beneficial components in the xanthoceras sorbifolia bunge flower is effectively increased, meanwhile, the xanthoceras sorbifolia bunge and tea mixed extract does not damage a human body, and the xanthoceras sorbifolia bunge and tea mixed extract is suitable for being used in treatment of prostatitis.
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Description

Technical Field

[0001] The invention relates to the technical field of Xanthoceras sorbifolia tea preparation technology, and more specifically to a preparation technology of a Xanthoceras sorbifolia tea mixed extract and an application thereof in treating prostatitis. Background Art

[0002] Xanthoceras sorbifo li um Bunge is a small deciduous tree of the Sapindaceae family. Its bark is gray-brown, its branches are brown-purple, and its twigs are covered with short soft hairs. Its leaves are odd-pinnate compound leaves, which are alternate. Its leaflets are short-stalked or sessile, lanceolate or nearly ovate, and have sharp serrations on the edges. Its flowers bloom before the leaves or at the same time. Its inflorescence is panicle, with many flowers. Its petals are white, red or yellow at the base, and have purple-red spots on the inside. Its sepals are oblong. Its capsule is like a cotton ball, with a hard, green shell. Its seeds are round, dark brown, hard, and smooth. Its flowering period is from April to May, and its fruiting period is from July to August.

[0003] Xanthoceras sorbifolia has high nutritional value and can be eaten as a vegetable. The Compendium of Materia Medica records that Xanthoceras sorbifolia can treat rheumatoid arthritis, effectively prevent high blood pressure, improve memory, improve cardiovascular function, and have antiviral and anti-AIDS effects.

[0004] At present, there are few actual applications of Xanthoceras sorbifolia flowers in the medical treatment of prostatitis, and the extraction rate of beneficial substances in Xanthoceras sorbifolia flowers is low when they are used conventionally.

[0005] Therefore, in view of this, the existing structure is studied and improved, and a preparation process of a mixed extract of Xanthoceras sorbifolia tea and its application in the treatment of prostatitis are provided, in order to achieve a more practical purpose. Summary of the invention

[0006] 1. Technical problems to be solved

[0007] In view of the problems existing in the prior art, the purpose of the present invention is to provide a preparation process of a mixed extract of Xanthoceras sorbifolia tea and its application in the treatment of prostatitis. The mixed extract of Xanthoceras sorbifolia tea can be made from Xanthoceras sorbifolia flowers as raw materials, and after multiple processing, a mixed extract product of Xanthoceras sorbifolia tea is finally prepared, and the extraction rate of beneficial ingredients in Xanthoceras sorbifolia flowers is effectively improved. At the same time, the mixed extract of Xanthoceras sorbifolia tea will not cause damage to the human body and is suitable for use in the treatment of prostatitis.

[0008] 2. Technical solution

[0009] To solve the above problems, the present invention adopts the following technical solutions.

[0010] The preparation process of Xanthoceras sorbifolia tea mixed extract, the specific implementation steps of the preparation process are as follows:

[0011] Step 1: Select Xanthoceras sorbifolia flowers and perform preliminary processing: Select the flowers of Xanthoceras sorbifolia and wash them with clean water, and then dry the washed flowers naturally;

[0012] Step 2, crushing the Xanthoceras sorbifolia flowers and obtaining a crude extract powder: crushing the Xanthoceras sorbifolia flowers by a crusher, then preparing an extract, adding the crushed material to the extract, stirring, extracting and filtering to obtain an extracted mixed solution, and then drying the mixed solution to obtain a dry crude extract powder;

[0013] Step 3, centrifuging the crude powder of the extract to obtain a refined powder of the extract: adding a sufficient amount of distilled water to the crude powder of the extract, stirring it thoroughly until it can no longer be dissolved, then filtering out the solid impurities therein, adding the remaining solution to a centrifuge, extracting the centrifuges separately, and drying them separately, thereby obtaining a refined powder of Xanthoceras sorbifolia flower;

[0014] Step 4: Add the mixture to form the final product of Xanthoceras sorbifolia tea mixed extract: quantitatively weigh the refined powder, add ethanol solvent and aromatic hydrocarbons, and configure to form the Xanthoceras sorbifolia tea mixed extract.

[0015] Furthermore, in the step 1, when selecting Xanthoceras sorbifolia flowers, select the Xanthoceras sorbifolia flowers and fruits with no yellow leaves for use, and after the washed flowers are dried, sterilized with ultraviolet rays and processed within 24 hours.

[0016] Furthermore, in the step 2, after the Xanthoceras sorbifolia flowers are crushed by a grinder, a 120-mesh sieve is used for sieving, and the powder that does not pass through the sieve is crushed again.

[0017] Furthermore, in the step 2, an ethanol solution with a concentration of 60% to 85% is selected as the extracting solution; the extraction temperature is controlled to be 85 to 90° C., the extraction time is controlled to be 1 to 2 hours, and the number of extractions is controlled to be no less than 4 times.

[0018] Furthermore, in the step 2, the mixed liquid is dried by windless drying, and the temperature during drying is controlled to be 55-65°C.

[0019] Furthermore, in the step three, the crude powder is ground before adding a sufficient amount of distilled water.

[0020] Furthermore, in the step three, during the centrifugal operation, the centrifuge speed is controlled to be 5000r / min, the centrifugation time is controlled to be 10 to 15 minutes, and after centrifugation, the centrifugal materials in the highest and lowest layers are removed, the centrifugal materials in other centrifugal layers are collected, and then dried by a windless drying method at a temperature of 55 to 65°C.

[0021] Application of a mixed extract of Xanthoceras sorbifolia tea in treating prostatitis, wherein the final form of the mixed extract of Xanthoceras sorbifolia tea is a cream.

[0022] Furthermore, the Xanthoceras sorbifolia tea mixed extract is in the form of a viscous granule or a compressed solid block when used. When used, water is heated to boiling, then cooled to 50-60° C., and the cooled water is added.

[0023] 3. Beneficial effects

[0024] Compared with the prior art, the advantages of the present invention are:

[0025] In the present scheme, in the application of Xanthoceras sorbifolia flower extraction and in the treatment of prostatitis, the Xanthoceras sorbifolia flower is sequentially selected, crushed, extracted with coarse powder, centrifuged, extracted with fine powder, and mixed to form the final Xanthoceras sorbifolia tea mixed extract product. In this process, the extraction rate of beneficial components in Xanthoceras sorbifolia flower can be effectively improved. At the same time, when the Xanthoceras sorbifolia tea mixed extract is applied to the treatment of prostatitis, it can be dissolved with water at 50-60°C. The final granule can be used for the treatment of prostatitis. At the same time, since the components in the Xanthoceras sorbifolia tea mixture are non-toxic or slightly toxic, they will not cause damage to the human body when used, and are suitable for use in the treatment of prostatitis. BRIEF DESCRIPTION OF THE DRAWINGS

[0026] Figure 1 The figure is a schematic flow chart of the preparation process of the mixed extract of Xanthoceras sorbifolia tea of ​​the present invention;

[0027] Figure 2 This is a schematic diagram of the use of the Xanthoceras sorbifolia flower mixed extract of the present invention. DETAILED DESCRIPTION

[0028] The technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention; it is obvious that the described embodiments are only part of the embodiments of the present invention, rather than all the embodiments, and all other embodiments obtained by ordinary technicians in this field based on the embodiments of the present invention without making creative work are within the scope of protection of the present invention.

[0029] Embodiment 1:

[0030] See also Figure 1 , the preparation process of the mixed extract of Xanthoceras sorbifolia tea, the specific implementation steps of the preparation process are as follows:

[0031] Step 1, select Xanthoceras sorbifolia flowers and perform preliminary processing: select the flowers of Xanthoceras sorbifolia and use clean water to wash them, and the washed flowers are naturally dried. By controlling the quality of the raw material Xanthoceras sorbifolia flowers, the quality of the final Xanthoceras sorbifolia tea mixed extract can be guaranteed;

[0032] Step 2, crushing the Xanthoceras sorbifolia flowers and obtaining a crude extract powder: crushing the Xanthoceras sorbifolia flowers with a crusher, then preparing an extract, adding the crushed material to the extract, stirring, extracting and filtering to obtain an extracted mixed solution, and then drying the mixed solution to obtain a dry crude extract powder, thereby removing most of the unusable impurities in the Xanthoceras sorbifolia flowers;

[0033] Step 3, centrifuging the crude powder of the extract to obtain a refined powder of the extract: adding a sufficient amount of distilled water to the crude powder of the extract, stirring it thoroughly until it can no longer be dissolved, then filtering out the solid impurities therein, adding the remaining solution to a centrifuge, extracting the centrifuges separately, and drying them separately, thereby obtaining a refined powder of the Xanthoceras sorbifolia flower, so that the beneficial substances in the Xanthoceras sorbifolia flower can be effectively extracted;

[0034] Step 4: Add the mixture to form the final product of Xanthoceras sorbifolia tea mixed extract: quantitatively weigh the refined powder, add ethanol solvent and aromatic hydrocarbons, and configure to form the Xanthoceras sorbifolia tea mixed extract.

[0035] Specifically, in step one, when selecting Xanthoceras sorbifolia flowers, select flowers and fruits with no yellow leaves for use, and after the washed flowers are dried, use ultraviolet light for sterilization to treat viruses and bacteria in the flowers, and the treatment should be carried out within 24 hours to avoid the loss of beneficial substances in the flowers.

[0036] Specifically, in step 2, after the Xanthoceras sorbifolia flowers are crushed by a grinder, they are sieved using a 120-mesh sieve, and the powder that does not pass through the sieve is crushed again. At this time, the Xanthoceras sorbifolia flowers can be fully crushed, thereby improving the dissolution efficiency and extraction effect of the subsequent Xanthoceras sorbifolia flower powder.

[0037] Specifically, in step 2, an ethanol solution with a concentration of 60% to 85% is selected as the extracting solution;

[0038] The extraction temperature is controlled at 85-90°C, the extraction time is controlled at 1-2h, the number of extractions is controlled to be no less than 4 times, the extraction conditions are controlled, the extraction effect is guaranteed, and the utilization rate of the beneficial substances in the Xanthoceras sorbifolia flowers is improved.

[0039] Specifically, in step 2, the mixed liquid is dried by windless drying, and the drying temperature is controlled to be 55-65°C. Windless drying can avoid dust from the dried powder. At the same time, controlling the temperature can prevent the beneficial effects from being decomposed by high temperature.

[0040] Specifically, in step three, before adding a sufficient amount of distilled water, the crude powder is ground to avoid agglomeration of the crude powder and increase the dissolution rate of the powder.

[0041] Specifically, in step 3, during the centrifugation operation, the centrifuge speed is controlled to be 5000r / min, the centrifugation time is controlled to be 10 to 15 minutes, and after centrifugation, the centrifuged materials in the highest and lowest layers are removed, and the centrifuged materials in other centrifuged layers are collected. There are many impurities in the centrifuged materials in the highest and lowest layers, which may affect the practical effect of the final Xanthoceras sorbifolia tea mixed extract.

[0042] Then, the mixture is dried at a temperature of 55 to 65° C. without wind, and the drying method is the same as above, so as to avoid the beneficial effects being decomposed by high temperature.

[0043] Embodiment 2:

[0044] Based on the above embodiment 1, further description is given.

[0045] See also Figure 2 , application of a mixed extract of Xanthoceras sorbifolia tea in treating prostatitis, wherein the final form of the mixed extract of Xanthoceras sorbifolia tea is a cream.

[0046] Specifically, the Xanthoceras sorbifolia tea mixed extract is in the form of a viscous granule or a compressed solid block when used. When used, water is heated to boiling, then cooled to 50-60° C., and the cooled water is added to avoid thermal decomposition of other beneficial substances caused by high temperature.

[0047] Embodiment 3:

[0048] Based on the above-mentioned embodiment 2, further description is given.

[0049] The experiment of Xanthoceras sorbifolia tea mixed extract in the treatment of prostatitis was established. At this time, several adult male SD rats weighing 180 to 200 g were selected to make a prostatitis model, specifically:

[0050] The rats were anesthetized, and their limbs were fixed on a fixed board. The hair between the two hind limbs of the lower abdomen was cut off. The abdominal wall was cut along the midline of the abdomen under sterile conditions, and the lower abdomen was opened layer by layer to expose the bladder. The bladder and the seminal vesicles on both sides were gently lifted with forceps. The prostate body was located at the bottom of the seminal vesicle, and the dorsal lobe of the prostate attached to the inner side of the seminal vesicle was exposed. 1% carrageenan was injected into the left and right ventral lobes of the rat prostate in the model group, high-dose group, medium-dose group and low-dose group, respectively. The prostate, seminal vesicle and bladder were repositioned, the abdominal wall muscles and skin were sutured, disinfected, bandaged with gauze, and put back into the mouse cage as experimental rats for prostatitis.

[0051] Then, the test group was prepared, specifically:

[0052] Select 10 experimental rats, heat water to boiling, then cool to 50-60℃, add Xanthoceras sorbifolia tea mixed extract to the cooled water, and make into granules, which are fed to rats with prostatitis at regular intervals and in fixed quantities;

[0053] The experimental control group of prostatitis was prepared as follows:

[0054] Select 10 experimental rats and feed boiled and cooled drinking water to the rats with prostatitis at regular intervals and in fixed quantities;

[0055] A blank control group of healthy rats was prepared, specifically:

[0056] Ten healthy rats were selected and fed with boiled and cooled drinking water at regular intervals and in fixed quantities.

[0057] In addition, normal feeding was maintained for each rat for 4 weeks.

[0058] Test results:

[0059] Experimental group: The prostate tissue was significantly enlarged, became less soft, and lost its elasticity;

[0060] Experimental control group: The prostate tissue was significantly enlarged, partially necrotic, less soft, inelastic, and severely adhered to the surrounding tissues. Dark red or grayish white flaky nodules were visible on the surface of the prostate tissue.

[0061] Blank control group: normal prostate tissue;

[0062] In summary, the mixed extract of Xanthoceras sorbifolia tea has a certain therapeutic effect on the treatment of prostatitis

[0063] The above is only a preferred specific implementation of the present invention; however, the protection scope of the present invention is not limited thereto. Any technician familiar with the technical field can make equivalent replacements or changes according to the technical solution and its improved conception within the technical scope disclosed by the present invention, which should be covered by the protection scope of the present invention.

Claims

1. The preparation process of the mixed extract of Xanthoceras sorbifolia tea is characterized by: The specific implementation steps of this preparation process are as follows: Step 1: Select Xanthoceras sorbifolia flowers and perform preliminary processing: Select the flowers of Xanthoceras sorbifolia and wash them with clean water. After washing, the flowers are naturally dried. Step 2: Grinding the Xanthoceras sorbifolia flowers to obtain a crude extract powder: Grinding the Xanthoceras sorbifolia flowers using a grinder, then preparing an extract, adding the pulverized material to the extract, stirring, extracting, and filtering to obtain an extracted mixed solution, and then drying the mixed solution to obtain a dry crude extract powder; Step 3: Centrifuge the crude powder of the extract to obtain a refined powder of the extract: add sufficient distilled water to the crude powder of the extract, stir thoroughly until it can no longer be dissolved, filter out solid impurities, add the remaining solution to a centrifuge, extract the centrifuge separately, and dry them separately to obtain a refined powder of the Xanthoceras sorbifolia flower; Step 4: Add the mixture to form the final product of the Xanthoceras sorbifolia tea mixed extract: quantitatively weigh the refined powder, add ethanol solvent and aromatic hydrocarbons, and configure to form the Xanthoceras sorbifolia tea mixed extract.

2. The preparation process of the Xanthoceras sorbifolia tea mixed extract according to claim 1, wherein: In the step 1, when selecting Xanthoceras sorbifolia flowers, select Xanthoceras sorbifolia flowers and fruits without yellow leaves for standby use, and after the washed flowers are dried, sterilize them with ultraviolet rays and treat them within 24 hours.

3. The preparation process of the Xanthoceras sorbifolia tea mixed extract according to claim 1, wherein: In the step 2, after the Xanthoceras sorbifolia flowers are crushed by a grinder, they are sieved using a 120-mesh sieve, and the powder that does not pass through the sieve is crushed again.

4. The preparation process of the Xanthoceras sorbifolia tea mixed extract according to claim 1, wherein: In the step 2, an ethanol solution with a concentration of 60% to 85% is selected as the extracting solution; The extraction temperature is controlled at 85-90°C, the extraction time is controlled at 1-2 hours, and the number of extractions is controlled at no less than 4 times.

5. The preparation process of the Xanthoceras sorbifolia tea mixed extract according to claim 1, wherein: In the step 2, the mixed liquid is dried in a windless drying manner, and the temperature during drying is controlled to be 55-65°C.

6. The preparation process of the Xanthoceras sorbifolia tea mixed extract according to claim 1, wherein: In the step 3, the crude powder is ground before adding sufficient distilled water.

7. The preparation process of the Xanthoceras sorbifolia tea mixed extract according to claim 1, wherein: In the step 3, during the centrifugation operation, the centrifuge speed is controlled to 5000 r / min, the centrifugation time is controlled to 10 to 15 minutes, and after centrifugation, the centrifugal materials in the highest and lowest layers are removed, the centrifugal materials in other centrifugal layers are collected, and then dried in a windless drying method at a temperature of 55 to 65° C.

8. Use of the mixed extract of Xanthoceras sorbifolia tea obtained according to any one of claims 1 to 7 in the treatment of prostatitis, characterized in that: The final form of the Xanthoceras sorbifolia tea mixed extract is a cream.

9. The use of the mixed extract of Xanthoceras sorbifolia tea in treating prostatitis according to claim 8, characterized in that: The Xanthoceras sorbifolia tea mixed extract is in the form of a viscous granule or a compressed solid block when used. When used, water is heated to boiling, then cooled to 50-60° C., and the cooled water is added.