External traditional Chinese medicine composition for treating verruca vulgaris as well as preparation method and application of external traditional Chinese medicine composition

Abstract

The invention discloses a verruca vulgaris washing formula which is prepared from the following components: 10 to 20g of herba equiseti hiemalis, 20 to 30g of herba portulacae, 10 to 20g of spina gleditsiae, 20 to 30g of rhizoma cyperi, 10 to 15g of rhizoma curcumae and 20 to 30g of fructus cnidii. The traditional Chinese medicine formula lotion disclosed by the invention is an external scrubbing agent, so that the lotion can be used at home without hospitalization; in addition, the traditional Chinese medicine lotion is higher in safety, is safer than oral medicines, local acid administration and external medicines, and is free of serious side effects caused by laser treatment and the like due to the fact that the components of the traditional Chinese medicine lotion are all traditional Chinese medicines; the treatment cycle of the lotion is about 4 weeks, and the interval time between two times of laser treatment is 2-4 weeks; the length of the whole treatment cycle may be several months to about one year, compared with the prior art, the treatment cycle is stable, relapse is avoided, and the economic burden of a patient can be reduced.

Description

Technical Field

[0001] The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for external use of common warts, and a preparation method and application thereof. Background Art

[0002] Common warts are a common skin disease caused by infection with the human papillomavirus (HPV). The virus is spread through direct contact, shared objects, or contaminated surfaces, and usually appears on the hands, feet, around the nails, fingers, and soles of the feet, which are prone to irritation. Common warts appear as small, granular bumps on the skin that may be round or oval in shape, with a rough surface and sometimes gray, brown, or yellow in color. They usually appear alone, but they may also gather in groups. Although common warts are benign and do not cause serious health problems, they may cause discomfort and tactile distress. Most common warts will disappear on their own and get better without treatment within a few months or a year or two. However, sometimes they may recur and appear again after being cured. There are various ways to treat common warts. Physical therapy includes cryotherapy and laser therapy, which can remove the warts by freezing or laser action; topical medications usually contain acid ingredients, which can soften and remove the warts. Surgical removal is also a treatment option. In severe or difficult to heal cases, doctors may recommend surgical removal of the warts.

[0003] Surgical resection or laser removal will cause pain to patients to a certain extent, and the cost of treatment will also increase. The therapeutic effect of cryotherapy is not very ideal, and recurrence may occur.

[0004] Traditional Chinese medicine is non-toxic and non-invasive for common warts, and is currently a better way to treat common warts. The purpose of the present invention is to provide a Chinese medicine composition for external use of common warts. Summary of the invention

[0005] In order to solve the above technical problems, the present invention designs a Chinese medicine composition for external use on common warts, a preparation method and an application thereof. The formula overcomes the limitations of the current treatment effects of common warts, the limited treatment methods and the serious side effects of therapeutic drugs. In addition, the Chinese medicine composition for external use on common warts provided by the present invention, a preparation method and an application thereof are used for treatment. Since it is an external scrub, hospitalization is not required and the patient can use it at home. Compared with laser treatment and cryotherapy, the Chinese medicine composition is easy to use. The treatment cycle is stable and will not relapse, and the economic burden of the patient can be reduced.

[0006] To achieve the above-mentioned purpose, the present invention discloses a Chinese medicine composition for external use on common warts, comprising the following raw materials in proportion by mass: 10-20 parts of horsetail herb, 20-30 parts of purslane, 10-20 parts of Gleditsia sinensis, 20-30 parts of Cyperus rotundus, 10-15 parts of Curcuma zedoariae, and 20-30 parts of Cnidium monnieri;

[0007] Furthermore, the Chinese medicine composition for external use on common warts comprises the following raw materials by mass: 15 parts of horsetail herb, 30 parts of purslane, 15 parts of Gleditsia sinensis, 30 parts of Cyperus rotundus, 12 parts of Curcuma zedoariae, and 30 parts of Cnidium monnieri;

[0008] Furthermore, the Chinese medicine composition for external use on common warts comprises the following raw materials by mass: 10 parts of horsetail herb, 20 parts of purslane, 10 parts of Gleditsia sinensis, 10 parts of Cyperus rotundus, 10 parts of Curcuma zedoariae, and 20 parts of Cnidium monnieri;

[0009] Furthermore, the Chinese medicine composition for external use on common warts comprises the following raw materials by mass: 15 parts of horsetail herb, 15 parts of purslane, 15 parts of Gleditsia sinensis, 25 parts of Cyperus rotundus, 13 parts of Curcuma zedoariae, and 25 parts of Cnidium monnieri;

[0010] Warts are mainly related to heat and toxic accumulation, blood stasis, etc., and the treatment mainly uses drugs that clear heat, detoxify, promote blood circulation and relieve blood stasis. This prescription uses Portulaca oleracea as the main ingredient to clear heat and detoxify, and Equisetum arvense is used as the auxiliary ingredients to clear heat and dispel wind, Gleditsia sinensis and Curcuma zedoaria are used to promote blood circulation and remove blood stasis. Cnidium monnieri is used to remove dampness, kill parasites, dispel wind and assist kidney yang, and Cyperus rotundus is used to regulate qi and resolve blood stasis. The whole prescription is comprehensive and can clear heat, dissipate blood stasis, regulate qi and strengthen the body.

[0011] Purslane, nature and flavor: cold, sour; meridians: heart, liver, spleen, large intestine; functions: clearing away heat and detoxifying, promoting diuresis and removing dampness, dispersing blood and relieving swelling, heat toxins, diarrhea, carbuncle, sore, furuncle;

[0012] Horsetail Herb, nature and flavor: sweet, bitter, neutral; meridians: lung, liver, gallbladder; functions and indications: dissipate wind-heat, remove eye opacity. Used for wind-heat red eyes, tears in the wind, and cloudiness in the eyes.

[0013] Gleditsia sinensis, pungent in taste, warm in nature; enters the liver, lung, and stomach meridians; functions and indications: detumescence, expelling toxins, pus discharge, and insecticide. Used for carbuncle at the beginning or pus formation without ulceration; external treatment of scabies, leprosy.

[0014] Curcuma zedoaria, nature and flavor: pungent, bitter, warm; meridians: liver and spleen; functions and indications: promoting qi and removing blood, eliminating stagnation and relieving pain. Used for treating lumps and masses, blood stasis and amenorrhea, food stagnation and pain; early cervical cancer.

[0015] Cyperus rotundus, nature and flavor: pungent, slightly bitter, slightly sweet, neutral; meridians: liver, spleen, triple burner meridians; functions and indications: promoting qi and relieving depression, regulating menstruation and relieving pain. It is used for liver depression and qi stagnation, chest, flank, abdominal distension and pain, indigestion, chest and abdominal distension, cold hernia abdominal pain, breast distension and pain, irregular menstruation, amenorrhea and dysmenorrhea.

[0016] Cnidium monnieri, nature and flavor: pungent, bitter, warm; slightly toxic; meridians: kidney meridian; functions and indications: warming the kidney and strengthening yang, drying dampness, dispelling wind, killing insects. Used for impotence, cold uterus, cold and damp leucorrhea, dampness and back pain; external treatment of vulvar eczema, vaginal itching in women; trichomonas vaginitis.

[0017] Another object of the present invention is to provide a method for preparing a Chinese medicine composition for external use on common warts, the preparation method comprising the following steps:

[0018] S1: Soak the Chinese medicine according to the above ratio for 0.5-1 hour;

[0019] S2: Boil it for half an hour with high heat, then simmer it for 1 hour with low heat. Wash the affected area of ​​common warts once a day for at least 30 minutes each time. 4 consecutive weeks constitute a course of treatment.

[0020] Further, by mass, 15 parts of Herba Equisetum, 30 parts of Herba Portulacae Oleraceae, 15 parts of Spina Gleditsiae, 30 parts of Rhizoma Cyperi, 12 parts of Rhizoma Curcumae, and 30 parts of Fructus Cnidium.

[0021] Another object of the present invention is to provide a product for external use on common warts, the product comprising a foaming lotion and an aerosol;

[0022] The foaming agent is prepared by washing, drying, and grinding the above-mentioned formula and proportion for treating common warts into powder, and then packaging it according to a certain packaging amount;

[0023] The aerosol is prepared by boiling the drug liquid through the above drug raw material ratio and preparation method, and then the drug liquid is filled into a corresponding container through filtering, cooling, distillation, concentration and other means to prepare a spray.

[0024] The beneficial effects of the present invention are:

[0025] The invention discloses a method that overcomes the limitations of the current treatment effect of common warts, the limited treatment methods and the serious side effects of the treatment drugs; in addition, the invention provides a Chinese medicine composition for external use of common warts, a preparation method and an application thereof for treatment. Since it is an external scrub, hospitalization is not required and the patient can use it at home. Compared with laser treatment and cryotherapy, the method is simple to use. In addition, the treatment cycle of the wash prescription of the invention is about 4 weeks, while the interval between two laser treatments is between 2 and 4 weeks. The length of the entire treatment cycle may be from several months to about one year. In comparison, the treatment cycle is stable and will not recur, and the economic burden of the patient can be reduced. DETAILED DESCRIPTION

[0026] The present invention is further illustrated by the following examples

[0027] Example 1

[0028] A Chinese medicine composition for external use on common warts, a preparation method and an application thereof, wherein the Chinese medicine ingredients and weight are: 15 parts of horsetail herb, 30 parts of purslane, 15 parts of thorns of Gleditsia sinensis, 30 parts of cyperus rotundus, 12 parts of zedoaria, and 30 parts of cnidium monnieri; the preparation method of the washing formula is: first soaking the medicine for 0.5-1 hour, first boiling it with high heat for half an hour, then decocting it with low heat for 1 hour, filtering the medicine liquid with a filter after it cools down, and then placing it for use;

[0029] Typical treatment of common warts, patient 1: Shao * Kai, female, 40 years old, sales manager; treatment and symptoms: several wart-like growths on the front part of the right sole for more than a year, the larger ones have been worn into a flat shape, painless and itchy, not treated in other hospitals, came to my clinic today for medical treatment, and the diagnosis was common warts; the common warts washing prescription of the present invention was given, and the affected area was soaked once a day with the Chinese medicine decoction, each time for no less than half an hour, for 4 consecutive weeks; after a course of treatment, the patient's sole warts except the larger ones all atrophied and fell off. The larger ones also atrophied and collapsed, and after about ten days, they gradually dried and detached from the sole of the foot from one side; after a few days after all the warts fell off, there were no obvious scars; follow-up has been more than 5 years, and there has been no recurrence.

[0030] Example 2

[0031] A Chinese medicine composition for external use on common warts, a preparation method and an application thereof, wherein the Chinese medicine ingredients and weight are: 15 parts of horsetail herb, 30 parts of purslane, 15 parts of thorns of Gleditsia sinensis, 30 parts of cyperus rotundus, 12 parts of zedoaria, and 30 parts of cnidium monnieri; the preparation method of the washing formula is: first soaking the medicine for 0.5-1 hour, first boiling it with high heat for half an hour, then decocting it with low heat for 1 hour, filtering the medicine liquid with a filter after it cools down, and then placing it for use;

[0032] Typical treatment of common warts, patient 2: Hu*, male, 70 years old, retired worker; treatment and symptoms: multiple warts on the radial side of the right hand, some large and some small, no redness and swelling, no pain or itching. Self-reported a medical history of more than two years. Two years ago, there was only one wart. I listened to other people's words and pulled out the wart by myself. At that time, it was painful and bleeding. After the wound healed, two to three new warts grew again. I also used folk prescriptions (specific medicines are unknown). The warts were corroded by more than half and basically tended to be flat. Soon after, new warts grew again. After several self-help treatments, I came to see a doctor; the diagnosis was: common warts; the common warts washing recipe of the present invention was given to soak in decoction, and the affected part was soaked once a day with the Chinese medicine decoction, at least 30 minutes each time, for 4 consecutive weeks; after 4 weeks, the warts fell off completely without leaving scars, and there was no recurrence after two years of follow-up.

[0033] Example 3

[0034] A Chinese medicine composition for external use on common warts, a preparation method and an application thereof, wherein the Chinese medicine ingredients and weight are: 15 parts of horsetail herb, 30 parts of purslane, 15 parts of thorns of Gleditsia sinensis, 30 parts of cyperus rotundus, 12 parts of zedoaria, and 30 parts of cnidium monnieri; the preparation method of the washing formula is: first soaking the medicine for 0.5-1 hour, first boiling it with high heat for half an hour, then decocting it with low heat for 1 hour, filtering the medicine liquid with a filter after it cools down, and then placing it for use;

[0035] Treatment of a typical patient with common warts, Patient 3: Ding * Qin, female, 32 years old, nurse; symptoms and treatment: A wart-like growth appeared on the little finger of the left hand for two weeks, with no discomfort, itching or pain, and no treatment was given to the clinic. It was diagnosed as common warts, and the patient was given the Chinese medicine washing prescription of the present invention for external soaking, once a day, at least 30 minutes each time, for 4 consecutive weeks; after 4 weeks of use, the wart body shrank and fell off, leaving no scars, and there was no recurrence during the 3-year follow-up.

[0036] The preferred embodiments of the present invention disclosed above are only used to help explain the present invention. The preferred embodiments do not describe all the details in detail, nor do they limit the invention to only the specific implementation methods described.

Claims

1. A Chinese medicine composition for external use for common warts, characterized in that: The raw materials of the traditional Chinese medicine composition are divided into the following proportions by mass: 10-20 parts of horsetail herb, 20-30 parts of purslane, 10-20 parts of gleditsia thorn, 20-30 parts of cyperus rotundus, 10-15 parts of zedoaria, and 20-30 parts of cnidium monnieri.

2. A Chinese medicine composition for external use for common warts according to claim 1, characterized in that: The preparation method comprises the following raw materials by weight: 15 parts of horsetail herb, 30 parts of purslane, 15 parts of gleditsia spinosa, 30 parts of cyperus rotundus, 12 parts of zedoaria, and 30 parts of cnidium monnieri.

3. A Chinese medicine composition for external use on common warts according to claim 1, comprising the following raw materials in parts by mass: 10 parts of horsetail herb, 20 parts of purslane, 10 parts of gleditsia thorn, 10 parts of cyperus rotundus, 10 parts of curcuma, and 20 parts of cnidium monnieri.

4. A Chinese medicine composition for external use on common warts according to claim 1, comprising the following raw materials in parts by mass: 15 parts of horsetail herb, 15 parts of purslane, 15 parts of gleditsia thorn, 25 parts of cyperus rotundus, 13 parts of curcuma, and 25 parts of cnidium monnieri.

5. A method for preparing a common wart washing prescription as described in any one of claims 1 to 4, characterized in that: The following steps are involved: S1: Soak the Chinese medicine according to the above ratio for 0.5-1 hour; S2: Boil all the medicines together over high heat for half an hour, then simmer over low heat for 1 hour.

6. Use of a Chinese medicinal composition for external use on common warts as claimed in any one of claims 1 to 4 in the preparation of a product for external use on common warts.

7. The use according to claim 6, characterized in that: The common warts external-use product is a foaming wash, which is prepared by washing, drying, and grinding the above-mentioned formula and proportion for treating common warts into powder, and then packaging it according to a certain packaging amount.

8. The aerosol prepared by the method for preparing a common wart washing prescription according to claim 6, characterized in that: The aerosol is prepared by boiling the drug liquid through the above drug raw material ratio and preparation method, and then the drug liquid is filled into a corresponding container through filtering, cooling, distillation, concentration and other means to prepare a spray.