Fixture for collection suite

Abstract

A clip (100) for a collection kit is provided with: a kit holding part (102); a first adapter support section (104) to which the first adapter (21a) is fixed; a second adapter support section (106) to which the second adapter (21b) is fixed; a first bottle fixing part (108) for fixing the first culture bottle (90); a second bottle fixing part (110) for fixing a second culture bottle (92); and a lifting mechanism (112) that moves the kit holding part (102) relative to the first bottle fixing part (108) and the second bottle fixing part (110) in the vertical direction.

Description

Technical Field

[0001] The invention relates to a clamp for a collection kit for connecting the collection kit to a culture bottle. Background Art

[0002] Blood products include red blood cell products, plasma products, platelet products, and whole blood products. As for blood products, products containing the components required by patients will be used for blood transfusion. Blood products are stored and transported in medical bags. In order to ensure the safety of blood products, a small amount of samples are sometimes collected for culture inspection. In the culture inspection, the presence of pathogens is detected by collecting the sample in a culture bottle and placing the culture bottle in an environment suitable for bacterial proliferation.

[0003] For example, the inspection of platelet preparations is performed according to the following steps. A small-volume collection bag is connected to a medical bag containing platelet preparations (hereinafter referred to as a platelet bag). Then, a portion of the platelet preparation in the platelet bag is transferred to the collection bag. Next, the collection bag is separated from the platelet bag.

[0004] Next, the collection bag is transported to a clean bench. In the clean bench, the platelet preparation in the collection bag is injected into a blood culture bottle. Before the injection, the tube of the collection bag is connected to the tube extending from the sample collection tube. Based on the scale of the sample collection tube, a prescribed amount of the platelet preparation is transferred from the collection bag to the sample collection tube.

[0005] Then, the operator operates the valve of the sample collection tube while visually observing the scale of the sample collection tube, and transfers a specified amount of platelet preparation from the sample collection tube to the blood culture bottle. The culture test performs anaerobic culture and aerobic culture. Therefore, the platelet preparation is divided into a culture bottle for anaerobic culture and a culture bottle for aerobic culture. Then, the culture bottle is set in the culture device and provided for the culture test for a specified period of time.

[0006] For example, US Pat. No. 8,777,921 discloses a collection kit for collecting a sample from a medical bag. Summary of the invention

[0007] As a kit for collecting a predetermined amount of sample from a blood product bag, a collection kit having an inflow tube, a collection bag, an outflow port, and an adapter is considered. When a large number of blood products are cultured and tested, it is required to improve the operation efficiency of the culture test. Therefore, it is desired to be able to easily connect the adapter to the culture bottle.

[0008] An object of the present invention is to solve the above-mentioned problems.

[0009] (1) One embodiment of the present invention is a clamp for a collection kit, which is a clamp for a collection kit for connecting the collection kit to a culture bottle, wherein the collection kit comprises: an inflow tube connected to a medical bag containing a collection object; a collection bag connected downstream of the inflow tube, having a first receiving chamber and a second receiving chamber and having a connecting flow path connecting the first receiving chamber and the second receiving chamber; a first outflow port connected to the first receiving chamber; a second outflow port connected to the second receiving chamber; a first adapter connected downstream of the first outflow port and connectable to a first culture bottle; and a second adapter connected downstream of the second outflow port and connectable to a second culture bottle.

[0010] The aforementioned collection kit clamp comprises: a kit holding portion that holds the aforementioned collection kit; a first adapter supporting portion that is provided on the aforementioned kit holding portion and supports the aforementioned first adapter; a second adapter supporting portion that is provided on the aforementioned kit holding portion and supports the aforementioned second adapter; a first bottle fixing portion that is arranged below the aforementioned kit holding portion and fixes the aforementioned first culture bottle; a second bottle fixing portion that is arranged below the aforementioned kit holding portion and fixes the aforementioned second culture bottle; and a lifting mechanism that causes the aforementioned kit holding portion to move relative to the aforementioned first bottle fixing portion and the aforementioned second bottle fixing portion in the up-and-down direction.

[0011] (2) In the clamp for the collection kit described in the above item (1), the aforementioned kit holding portion may have: a base portion fixed to the aforementioned lifting mechanism; and a plurality of holding pins protruding from the aforementioned base portion, wherein the holding pins can be inserted into holding holes formed in the aforementioned collection bag of the aforementioned collection kit.

[0012] (3) In the clamp for the collection kit described in the above item (2), the collection bag may have four corners arranged in a manner surrounding the first receiving chamber and the second receiving chamber, and the plurality of retaining pins may have four retaining pins for retaining the four corners of the collection bag.

[0013] (4) In the clamp for a collection kit described in the above item (1) or (3), the kit holding portion may include a base portion fixed to the lifting mechanism, the first adapter supporting portion may include a pair of first protrusions protruding from the base portion and separated from each other in the horizontal direction, and the first adapter is clamped between the pair of first protrusions, and the second adapter supporting portion may include a pair of second protrusions protruding from the base portion and separated from each other in the horizontal direction, and the second adapter is clamped between the pair of second protrusions.

[0014] (5) In the clamp for a collection kit described in any one of items (1) to (4) above, the collection bag may have a tubular portion forming the middle portion of the connecting flow path, and the kit holding portion may have a clamping portion that closes the connecting flow path when the tubular portion is inserted.

[0015] (6) In the clamp for a collection kit according to the above item (5), the clamping portion may have a V-shaped clamping groove with its apex facing downward.

[0016] (7) In the collection kit jig according to any one of the above items (1) to (6), the lifting mechanism can move the kit holding portion in the up-down direction.

[0017] (8) In the collection kit clamp according to any one of the above items (1) to (6), the lifting mechanism can move the first bottle fixing portion and the second bottle fixing portion in the up-down direction.

[0018] According to the present invention, the collection kit is held in the kit holding part, the first adapter and the second adapter are fixed to the first adapter supporting part and the second adapter supporting part respectively, the first culture bottle and the second culture bottle are fixed to the first bottle fixing part and the second bottle fixing part respectively, and the kit holding part holding the collection kit is lowered by the lifting mechanism, thereby connecting the first adapter and the second adapter to the first culture bottle and the second culture bottle respectively. Therefore, the collection object can be easily transferred from the collection kit to the two culture bottles. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] [ Figure 1 ] Figure 1 It is a perspective view of the clamp for the collection kit according to the first embodiment of the present invention.

[0020] [ Figure 2 ] Figure 2 This is an overall picture of the acquisition kit.

[0021] [ Figure 3 ] Figure 3 Detailed diagram of the lifting mechanism in the acquisition kit fixture.

[0022] [ Figure 4 ] Figure 4 This is a diagram showing a state where a collection object is collected in a collection kit.

[0023] [ Figure 5 ] Figure 5 This is a diagram showing a state where the collection kit is connected to a culture bottle.

[0024] [ Figure 6 ] Figure 6 This is an overall diagram of the acquisition kit involved in other components.

[0025] [ Figure 7 ] Figure 7 It is a perspective view of a clamp for a collection kit according to a second embodiment of the present invention.

[0026] [ Figure 8 ] Figure 8 It is a perspective view of a clamp for a collection kit according to a third embodiment of the present invention.

[0027] [ Fig. 9 ] Fig. 9 This is a perspective view of a clamp for a collection kit according to a fourth embodiment of the present invention. DETAILED DESCRIPTION

[0028] Figure 1 The collection kit clamp 100 according to the first embodiment shown is used to connect the collection kit 10 to the first culture bottle 90 and the second culture bottle 92. The collection kit 10 is used to transfer a blood product as a collection object to the culture bottles 90 and 92. The collection kit 10 is used in a culture test for confirming the safety of a blood product in a business such as a blood center that manufactures a blood product. The culture test is a test for culturing anaerobic bacteria and aerobic bacteria. Therefore, in the culture test, two bottles are used, namely, a culture bottle 90 for anaerobic culture (hereinafter, also referred to as "first culture bottle 90") and a culture bottle 92 for aerobic culture (hereinafter, also referred to as "second culture bottle 92") . The collection kit 10 is used to collect a liquid sample (platelet product) and dispense it into two culture bottles 90 and 92 in a specified amount.

[0029] In the present embodiment, an example in which a platelet product is used as a blood product will be described below. However, the blood product collected by the collection kit 10 may be a red blood cell product, a plasma product, or a whole blood product.

[0030] like Figure 2 As shown, the collection kit 10 includes an inflow tube 12, a collection bag 14, a first sealing member 16, a second sealing member 18, an exhaust valve 20, a first adapter 21a, and a second adapter 21b. In the collection kit 10, based on the configuration state during use, the direction in which the inflow tube 12 and the exhaust valve 20 are located is referred to as the upper side or the top, and the direction in which the first adapter 21a and the second adapter 21b are located is referred to as the lower side or the bottom. In addition, the direction perpendicular to the up-down direction and along the plane of the collection bag 14 is referred to as the width direction, and the direction perpendicular to the plane of the collection bag 14 is referred to as the thickness direction.

[0031] The inflow tube 12 is a translucent medical tube formed of a thermoplastic resin such as vinyl chloride resin. The inflow tube 12 can be connected to or separated from other medical tubes without exposing the inside to the outside air by, for example, a sterile joint device, a tube seal, etc. The inflow tube 12 has a first end 12a on the upstream side and a second end 12b on the downstream side. The first end 12a is welded and sealed in the initial state. The second end 12b is connected to the upper end of the collection bag 14.

[0032] The collection bag 14 has two flexible sheets 22 overlapped in the thickness direction. The two flexible sheets 22 are welded to each other at a plurality of welded portions. The flexible sheet 22 has: a first region 22a for forming one storage chamber (a first storage chamber 26); a second region 22b for forming another storage chamber (a second storage chamber 28); and a connecting region 22c connecting the first region 22a and the second region 22b. The first region 22a has a rectangular shape of the same size as the second region 22b when viewed from above.

[0033] The connecting region 22c extends in the width direction and integrally connects the first region 22a and the second region 22b. The flexible sheet 22 has a pair of notches 22d that cut the flexible sheet 22 into a rectangular shape on the upper and lower sides of the connecting region 22c. The connecting region 22c is formed between the upper and lower notches 22d. The connecting region 22c is located in the center of the first region 22a and the second region 22b in the vertical direction, but is not particularly limited.

[0034] The flexible sheet 22 further includes an upper connecting region 22e connecting the upper portion of the first region 22a with the upper portion of the second region 22b, and a lower connecting region 22f connecting the lower portion of the first region 22a with the lower portion of the second region 22b. The collection bag 14 is reinforced by the upper connecting region 22e and the lower connecting region 22f.

[0035] The collection bag 14 includes a first receiving chamber 26, a second receiving chamber 28, and a connecting flow path 30 defined by a welded portion. The first receiving chamber 26 is formed in the first region 22a of the flexible sheet 22. The first receiving chamber 26 receives the platelet preparation introduced into the first culture bottle 90. The first receiving chamber 26 bulges in the thickness direction of the flexible sheet 22 in an initial state (a state when the product is provided). In the first receiving chamber 26, one flexible sheet 22 is separated from another flexible sheet 22 in the thickness direction. The first receiving chamber 26 has a volume for receiving a predetermined amount (e.g., about 8 mL to about 10 mL) of the platelet preparation.

[0036] The collection bag 14 has an inflow port 32 connected to the first storage chamber 26, and a first outflow port 34. The inflow port 32 is connected to the upper end of the first storage chamber 26 of the collection bag 14. The inflow port 32 is connected to the second end 12b of the inflow tube 12, so that the inflow tube 12 and the first storage chamber 26 are connected. The first outflow port 34 is connected to the lower end of the first storage chamber 26. The first outflow port 34 is connected to the first sealing member 16. The first adapter 21a is connected to the first outflow port 34 via the first sealing member 16.

[0037] The second storage chamber 28 is formed in the second region 22b of the flexible sheet 22. The second storage chamber 28 stores the platelet preparation introduced into the second culture bottle 92. The second storage chamber 28 has the same shape as the first storage chamber 26 and has a volume for storing a predetermined amount (e.g., about 8 mL to about 10 mL) of the platelet preparation as the first storage chamber 26.

[0038] The collection bag 14 has a second outflow port 36 and an exhaust port 38 connected to the second storage chamber 28. The second outflow port 36 is connected to the lower end of the second storage chamber 28 of the collection bag 14. The second outflow port 36 is connected to the second sealing member 18. The second adapter 21b is connected to the second outflow port 36 via the second sealing member 18. The exhaust port 38 is connected to the upper end of the second storage chamber 28. The exhaust valve 20 is connected to the exhaust port 38.

[0039] The connecting flow path 30 is a flow path connecting the first storage chamber 26 and the second storage chamber 28. The end 30a on the upstream side of the connecting flow path 30 is connected to the upper part of the first storage chamber 26. The connecting flow path 30 extends obliquely upward from the end 30a, bends at the top 30b and extends downward. The connecting flow path 30 extends downward to the center of the vertical direction of the collection bag 14 on the downstream side of the top 30b, and bends in the width direction at the bend 30c. The connecting flow path 30 forms an intermediate portion 30d on the downstream side of the bend 30c, and the intermediate portion 30d extends in the width direction in a direction away from the first storage chamber 26.

[0040] The middle part of the flow path direction of the connecting flow path 30 is located at the center of the width direction of the middle part 30d. The middle part 30d extends along the connecting area 22c of the flexible sheet 22 and extends along the second area 22b. The connecting flow path 30 has a curved portion 30e on the downstream side of the middle part 30d. The connecting flow path 30 is bent downward at the curved portion 30e. The connecting flow path 30 on the downstream side of the curved portion 30e changes direction at the return portion 30f, and the end 30g on the downstream side located downstream of the return portion 30f is connected to the lower part of the second storage chamber 28.

[0041] The connecting flow path 30 bulges in the thickness direction in the initial state. In addition, the middle portion 30d of the connecting flow path 30 forms a tubular tubular portion 31, and the portion of the tubular portion 31 passing through the connecting area 22c extends elongated in the width direction. The tubular portion 31 is sealed by a welded portion having narrow upper and lower ends.

[0042] The collecting bag 14 has four corner portions 14a arranged so as to surround the first storage chamber 26 and the second storage chamber 28. Holding holes 14h are formed in the four corner portions 14a.

[0043] The first sealing member 16 seals the first outflow port 34 in the initial state, preventing the fluid from passing through the first receiving chamber 26 and the first adapter 21a. The first sealing member 16 is a cylindrical member having a breakable plug inside. When the plug is bent in the internal flow path in the initial state, the plug breaks, allowing the internal flow path to be opened. The second sealing member 18 is also a member similar to the first sealing member 16, and seals the second outflow port 36 in the initial state, preventing the fluid from passing through the second receiving chamber 28 and the second adapter 21b.

[0044] The exhaust valve 20 is connected to the second receiving chamber 28 and the first receiving chamber 26 through the exhaust port 38. The exhaust valve 20 has a filter that allows gas to pass through and prevents liquid from passing through. The exhaust valve 20 may have a hydrophilic filter, but is not particularly limited. In the case of the exhaust valve 20 having a hydrophilic filter, after the first receiving chamber 26 and the second receiving chamber 28 are filled with the platelet preparation, when the platelet preparation comes into contact, the pores of the filter are closed by the liquid, and then the exhaust valve 20 prevents the passage of gas and liquid. Such an exhaust valve 20 can prevent air from flowing back to the second receiving chamber 28.

[0045] The first adapter 21a includes: a receiving tube 80 capable of receiving the neck of the first culture bottle 90; a tubular needle 82 disposed inside the receiving tube 80; and a rubber cover 84 covering the needle 82. The receiving tube 80 includes an openable and closable cover 86. The needle 82 can pierce the rubber stopper 93 (see FIG. 1 ) of the first culture bottle 90. Figure 1 ). When the needle 82 of the first adapter 21a penetrates the rubber plug 93 of the first culture bottle 90 and the first sealing member 16 is opened, the first culture bottle 90 is communicated with the first receiving chamber 26. When the needle 82 pierces the rubber plug 93 of the first culture bottle 90, the rubber cover 84 is pressed into the base end side, and the needle 82 penetrates the rubber cover 84. When the needle 82 is pulled out from the rubber plug 93 of the first culture bottle 90, the rubber cover 84 stretches by its elastic restoring force and covers the needle 82 again.

[0046] The second adapter 21 b has the same structure as the first adapter 21 a. When the needle 82 of the second adapter 21 b penetrates the rubber stopper 93 of the second culture bottle 92 and the second sealing member 18 is opened, the second culture bottle 92 and the second storage chamber 28 communicate with each other.

[0047] Next, Figure 1 The collection kit shown is constructed using a clamp 100 for illustration.

[0048] The collection kit jig 100 includes a kit holding portion 102 , a first adapter supporting portion 104 , a second adapter supporting portion 106 , a first bottle fixing portion 108 , a second bottle fixing portion 110 , and a lifting mechanism 112 .

[0049] The kit holding portion 102 can move in the up-down direction and hold the collection kit 10. The kit holding portion 102 has a base portion 114 fixed to the lifting mechanism 112. The base portion 114 is a plate-like member having a thickness in the horizontal direction, and is formed into a quadrilateral in this embodiment. It should be noted that the shape of the base portion 114 is not particularly limited. The base portion 114 can be displaced up and down by using the lifting mechanism 112. The back side 114b of the base portion 114 is fixed to the lifting mechanism 112.

[0050] The kit holding portion 102 has a plurality of holding pins 116 protruding from a base portion 114 as a fixing mechanism for fixing the collection bag 14 of the collection kit 10. The plurality of holding pins 116 protrude from a front surface 114f of the base portion 114. The plurality of holding pins 116 can be inserted into holding holes 14h formed in the collection bag 14 of the collection kit 10. The plurality of holding pins 116 are parallel to each other. The plurality of holding pins 116 has four holding pins 116 for holding the four corners 14a of the collection bag 14. Five or more holding pins 116 may also be provided.

[0051] The form of the fixing mechanism is not limited to the plurality of holding pins 116. Another form of the fixing mechanism may be a clamp structure that holds the peripheral edge of the collecting bag 14 at a plurality of locations.

[0052] The kit holder 102 has a structure for connecting the flow path 30 (see FIG. 1 ) when the tubular portion 31 of the collection kit 10 is inserted. Figure 2 ) is enclosed by a clamping portion 118. The clamping portion 118 has a V-shaped clamping groove 120 with its apex facing downward. The clamping portion 118 protrudes from the front surface 114f of the base portion 114. The clamping portion 118 is formed in a U-shape (J-shape). The clamping portion 118 has a clamping portion 119 extending upward from the lower portion of the U. The clamping groove 120 is formed in the clamping portion 119. The clamping portion 118 is arranged at a position surrounded by four retaining pins 116.

[0053] The kit holding part 102 further includes a tube holding part 121 capable of holding the inflow tube 12 of the collection kit 10. The tube holding part 121 includes a pair of holding protrusions 121a protruding from the front surface 114f of the base part 114. The inflow tube 12 is held between the pair of holding protrusions 121a.

[0054] The first adapter support portion 104 is provided on the kit holding portion 102, and fixes the first adapter 21a. The first adapter support portion 104 has a pair of first protrusions 105 that protrude from the front surface 114f of the base portion 114 and are separated from each other in the horizontal direction. The first adapter support portion 104 clamps the first adapter 21a between the pair of first protrusions 105. The inner surface of one first protrusion 105 and the inner surface of the other first protrusion 105 are holding surfaces for holding the first adapter 21a. The interval between the inner surface of one first protrusion 105 and the inner surface of the other first protrusion 105 is preferably set to be slightly smaller than the outer diameter of the first adapter 21a (holding tube). Thus, the first adapter 21a can be held with a moderate fixing force.

[0055] The first adapter support 104 further includes a pressing portion 104a that abuts against a shoulder (upper surface) of the housing tube 80 of the first adapter 21a. The pressing portion 104a is provided on the upper portion of the pair of first protrusions 105. When the first adapter 21a is connected to the first culture bottle 90, the pressing portion 104a can be used to prevent the first adapter 21a from being relatively displaced upward relative to the first adapter support 104.

[0056] The second adapter support portion 106 is provided on the kit holding portion 102, and fixes the second adapter 21b. The second adapter support portion 106 has a pair of second protrusions 107 that protrude from the front surface 114f of the base portion 114 and are separated from each other in the horizontal direction. The second adapter 21b is clamped between the pair of second protrusions 107. The inner surface of one second protrusion 107 and the inner surface of the other second protrusion 107 are holding surfaces for holding the second adapter 21b. The interval between the inner surface of one second protrusion 107 and the inner surface of the other second protrusion 107 is preferably set to be slightly smaller than the outer diameter of the second adapter 21b (housing tube 80). Thus, the second adapter 21b can be held with a moderate fixing force.

[0057] The second adapter support 106 further includes a pressing portion 106a that abuts against the shoulder (upper surface) of the housing tube 80 of the second adapter 21b. The pressing portion 106a is provided on the upper portion of the pair of second protrusions 107. When the second adapter 21b is connected to the second culture bottle 92, the pressing portion 106a can be used to prevent the second adapter 21b from being relatively displaced upward relative to the second adapter support 106.

[0058] The first adapter support portion 104 and the second adapter support portion 106 are arranged in the horizontal direction at the same height as each other.

[0059] The first bottle fixing part 108 is arranged below the kit holding part 102 to fix the first culture bottle 90. The second bottle fixing part 110 is arranged below the kit holding part 102 to fix the second culture bottle 92. The bottle fixing member 122 is fixed to the base 101 constituting the lower part of the collection kit clamp 100. The first bottle fixing part 108 and the second bottle fixing part 110 are integrally provided on the bottle fixing member 122.

[0060] The first bottle fixing portion 108 is arranged directly below the first adapter support portion 104. The first bottle fixing portion 108 has a U-shaped bottle holding groove 109 with an open top and side. The first culture bottle 90 is held in the bottle holding groove 109. The interval between one inner side surface and the other inner side surface of the bottle holding groove 109 is preferably set to be slightly smaller than the outer shape of the first culture bottle 90. Thus, the first culture bottle 90 can be held with an appropriate fixing force. The second bottle fixing portion 110 is arranged directly below the second adapter support portion 106. The second bottle fixing portion 110 is configured in the same manner as the first bottle fixing portion 108, and therefore a detailed description thereof is omitted.

[0061] The lifting mechanism 112 moves the kit holding portion 102 in the vertical direction. The lifting mechanism 112 includes a frame portion 126 fixed to the base 101 , a displacement portion 128 supported by the frame portion 126 so as to be liftable, and a lifting operation portion 130 attached to the frame portion 126 .

[0062] The frame portion 126 includes: a support bracket 132 fixed to the base 101; a support bracket 134 supported by the support bracket 132 and protruding upward; and a guide block 136 fixed to the support bracket 134. The guide block 136 is installed at a right angle to the support bracket 134 and extends in the horizontal direction. One end (first end 136a) of the guide block 136 is fixed to the support bracket 134. The displacement portion 128 is arranged at the other end (second end 136b) of the guide block 136. A guide hole 138 is formed at the second end 136b of the guide block 136, which penetrates in the up-down direction.

[0063] The frame 126 further includes a subframe 137 disposed between the guide block 136 and the base 101. The subframe 137 extends in the vertical direction. The upper end of the subframe 137 is connected between the first end 136a and the second end 136b of the guide block 136. The lower end of the subframe 137 is supported by the base 101.

[0064] The displacement unit 128 includes a lifting rod 140 inserted into the guide hole 138 of the guide block 136 and a support body 142 fixed to the lower end of the lifting rod 140. Figure 3As shown in FIG. 1 , in the lifting rod 140, a rack 144 is formed along the extension direction (up and down direction) of the lifting rod 140. Figure 1 As shown, a fixing seat 146 is fixed at the upper end of the lifting rod 140 .

[0065] A spring 148 as an example of an elastic member is disposed between the guide block 136 and the fixed seat 146. The spring 148 is a coil spring. The upper end of the spring 148 abuts against the fixed seat 146, and the lower end of the spring 148 abuts against the guide block 136. The lifting rod 140 is inserted into the inner side of the spring 148. The elastic force of the spring 148 acts in a manner to keep the displacement portion 128 in the initial position.

[0066] The positioning block 150 is fixed to the fixing seat 146. The positioning block 150 protrudes downward from the lower surface of the fixing seat 146. The lower surface of the positioning block 150 is opposite to the upper surface of the guide block 136. When the displacement part 128 descends, the lower end of the positioning block 150 abuts against the upper surface of the guide block 136, thereby stopping the displacement part 128 from descending.

[0067] The support body 142 is a block-shaped member extending in the horizontal direction. The base portion 114 of the kit holding portion 102 is fixed to the support body 142. Two guide rods 152 are inserted through two holes provided at both ends of the support body 142. The two guide rods 152 protrude upward from the base 101 in parallel with each other. The guide rods 152 guide the lifting and lowering of the support body 142. It should be noted that three or more guide rods 152 may also be provided.

[0068] The lifting operation unit 130 includes a rotating rod 156 rotatably supported on the guide block 136 and an operation rod 158 fixed to the rotating rod 156. The rotating rod 156 can rotate around a horizontal axis. Figure 3 As shown, the rotating rod 156 has a gear portion 160 meshed with the rack 144 of the lifting rod 140. The gear portion 160 is disposed inside the guide block 136. When the gear portion 160 rotates with the rotation of the rotating rod 156, the lifting rod 140 having the rack 144 meshed with the gear portion 160 rises or falls corresponding to the rotation direction of the gear portion 160.

[0069] exist Figure 1 In FIG. 1 , the operation rod 158 is a portion held by the user when operating the lifting operation unit 130, and is fixed at a right angle to the rotating rod 156. The user can rotate the rotating rod 156 by moving the operation rod 158.

[0070] The collection kit clamp 100 may further include a first electronic balance, a second electronic balance, a first weight display unit, and a second weight display unit. It should be noted that the first electronic balance, the second electronic balance, the first weight display unit, and the second weight display unit are not shown in the figure, but the first electronic balance and the second electronic balance may be respectively arranged directly below the two bottle holding grooves 109 in the bottle fixing member 122, for example. The first weight display unit and the second weight display unit may be arranged on the base 101 or the bottle fixing member 122, for example.

[0071] The first electronic balance measures the weight of the collection object transferred to the first culture bottle 90. The first weight display unit displays the value measured by the first electronic balance. The second electronic balance measures the weight of the collection object transferred to the second culture bottle 92. The second weight display unit displays the value measured by the second electronic balance. Therefore, the user can quickly grasp the accurate weight of each collection object in the first culture bottle 90 and the second culture bottle 92.

[0072] The collection kit 10 and the collection kit jig 100 configured as described above are used as follows. In the present embodiment, a collection method of dispensing a platelet preparation into two culture bottles 90 and 92 using the collection kit 10 will be described.

[0073] like Figure 4 As shown, a platelet bag 94 is connected to the collection kit 10. The platelet bag 94 is a medical bag containing a platelet preparation. The platelet bag 94 has a tube 96 for connection. The tube 96 is connected to the inflow tube 12. The tube 96 is connected to the inflow tube 12 using a sterile connection device without contact with the external air.

[0074] Next, the platelet preparation is introduced into the collection bag 14. In this step, the platelet bag 94 is arranged above the collection bag 14. The first sealing member 16 and the second sealing member 18 of the collection kit 10 are maintained in a closed state.

[0075] The platelet preparation flows out of the platelet bag 94 by gravity and flows into the collection bag 14 through the inflow tube 12. The platelet preparation flowing into the collection bag 14 flows into the first storage chamber 26 through the inflow port 32. The platelet preparation is stored in the first storage chamber 26, and the liquid level of the platelet preparation in the first storage chamber 26 rises. The air inside the first storage chamber 26 is squeezed out by the platelet preparation and discharged from the exhaust valve 20 through the connecting flow path 30 and the second storage chamber 28.

[0076] When the first storage chamber 26 is filled with the platelet preparation, the platelet preparation flows into the end 30a on the upstream side of the connecting flow path 30. Then, the platelet preparation flows from the upstream to the downstream in the connecting flow path 30, and flows into the second storage chamber 28 from the lower part of the second storage chamber 28. As the platelet preparation flows in, the liquid level of the platelet preparation inside the second storage chamber 28 rises. The air in the second storage chamber 28 is discharged from the exhaust valve 20. The second storage chamber 28 is filled with the platelet preparation. Furthermore, when the exhaust valve 20 contacts the platelet preparation, the exhaust valve 20 is closed to prevent the inflow of the platelet preparation. Thus, the introduction of the platelet preparation into the collection bag 14 is completed. A predetermined amount (for example, about 8 mL to 10 mL) of platelet preparation is contained in each of the first storage chamber 26 and the second storage chamber 28.

[0077] Then, the platelet bag 94 is separated from the inflow tube 12 by a tube seal (high frequency seal or ultrasonic seal) or the like. The tube seal separates the inflow tube 12 from the tube 96 of the platelet bag 94 and seals the first end 12a of the inflow tube 12 by welding. The inflow tube 12 and the tube 96 are separated without exposing the internal flow path to the outside air.

[0078] The removed platelet bag 94 is stored until the culture test is completed and then used. On the other hand, the collection kit 10 filled with the platelet preparation is carried into the clean bench. Figure 1 A collection kit clamp 100 is shown.

[0079] In the clean bench, users Figure 1 As shown, the collection kit 10 is mounted on the collection kit clamp 100. Specifically, the user inserts the plurality of retaining pins 116 into the plurality of retaining holes 14h provided in the collection bag 14, and fixes the first adapter 21a and the second adapter 21b to the first adapter support 104 and the second adapter support 106. Thus, the collection kit 10 is fixed (held) to the kit holding portion 102.

[0080] When the collection kit 10 is mounted on the kit holding portion 102, the tubular portion 31 of the collection bag 14 is inserted into the clamping groove 120 of the clamping portion 118. By inserting the tubular portion 31 into the clamping groove 120, the tubular portion 31 is flattened, and the connecting flow path 30 (see Figure 2) is closed. As a result, the communication between the first receiving chamber 26 and the second receiving chamber 28 of the collecting bag 14 is blocked, and the movement of the fluid between the first receiving chamber 26 and the second receiving chamber 28 is prevented. It should be noted that the tubular portion 31 can be sealed by cutting the tubular portion 31 using a tube seal. Alternatively, the tubular portion 31 can be sealed by welding the tubular portion 31 using ultrasonic sealing (or high-frequency sealing). In this case, there is no need to provide the clamping portion 118 in the kit holding portion 102.

[0081] The user fixes the first culture bottle 90 and the second culture bottle 92 to the first bottle fixing portion 108 and the second bottle fixing portion 110, respectively. The first culture bottle 90 and the second culture bottle 92 may be fixed to the first bottle fixing portion 108 and the second bottle fixing portion 110 before or after the collection kit 10 is fixed to the kit holding portion 102.

[0082] After the collection kit 10 , the first culture bottle 90 , and the second culture bottle 92 are set on the collection kit jig 100 as described above, the user then performs an operation for transferring the platelet preparation from the collection kit 10 to the first culture bottle 90 and the second culture bottle 92 .

[0083] Specifically, the user holds the operating lever 158 and moves it in the direction A (see Figure 1 ) moves. Therefore, Figure 5 As shown, the lifting operation unit 130 is rotated. With the rotation of the rotating rod 156 of the lifting operation unit 130, the rack 144 (see Figure 3 ) is lowered. As the lifting rod 140 is lowered, the base portion 114 fixed to the support body 142 is lowered, so the collection kit 10 fixed to the kit holding portion 102 is also lowered. When the lifting rod 140 is lowered, the spring 148 disposed between the fixing seat 146 and the guide block 136 is compressed in the axial direction. That is, the lifting rod 140 overcomes the elastic force of the spring 148 and is lowered.

[0084] As the collection kit 10 descends, the first culture bottle 90 is connected to the first adapter 21a, and the second culture bottle 92 is connected to the second adapter 21b. The needle 82 of the first adapter 21a penetrates the rubber stopper 93 of the first culture bottle 90 (see Figure 1 ), the needle portion 82 of the second adapter 21b penetrates the rubber stopper 93 of the second culture bottle 92.

[0085] Then, the first sealing member 16 is opened, the platelet preparation in the first storage chamber 26 is sucked out by the negative pressure of the first culture bottle 90, and a predetermined amount of the platelet preparation is introduced into the first culture bottle 90. In addition, the second sealing member 18 is opened, the platelet preparation in the second storage chamber 28 is sucked out by the negative pressure of the second culture bottle 92, and a predetermined amount of the platelet preparation is introduced into the second culture bottle 92.

[0086] Next, the user operates the lifting operation unit 130 to raise the collection kit 10. Figure 5 When the lifting operation unit 130 is rotated in the B direction, the kit holding unit 102 rises. As the kit holding unit 102 rises, the collection kit 10 held in the kit holding unit 102 also rises. As the collection kit 10 rises, the first adapter 21a is removed from the first culture bottle 90, and the second adapter 21b is removed from the second culture bottle 92. Through the above steps, the collection of the platelet preparation using the collection kit 10 is completed.

[0087] The collection kit 10 is a structure in which the collection bag 14 is formed integrally using two flexible sheets 22, so it can be manufactured at a low cost. In addition, since the number of times the tubes are joined and separated from each other can be suppressed to a minimum, the operation efficiency is excellent. Moreover, since there is no need to measure and collect the platelet preparation by visual measurement based on the scale line, the operation becomes easy and the measurement error can be reduced. In addition, in the collection kit 10, by closing the tubular portion 31 of the collection bag 14 with the clamping portion 118, etc., the first receiving chamber 26 and the second receiving chamber 28 can be reliably separated, and the platelet preparation can be prevented from moving between the first receiving chamber 26 and the second receiving chamber 28. Therefore, the collection kit 10 can suppress the deviation of the amount of the platelet preparation introduced into the first culture bottle 90 and the second culture bottle 92.

[0088] The collection kit clamp 100 according to the present embodiment achieves the following effects.

[0089] The collection kit 10 is held in the kit holding portion 102, the first adapter 21a and the second adapter 21b are fixed to the first adapter supporting portion 104 and the second adapter supporting portion 106, respectively, the first culture bottle 90 and the second culture bottle 92 are fixed to the first bottle fixing portion 108 and the second bottle fixing portion 110, respectively, and the kit holding portion 102 holding the collection kit 10 is lowered by the lifting mechanism 112, so that the first adapter 21a and the second adapter 21b are connected to the first culture bottle 90 and the second culture bottle 92, respectively. Therefore, the collection object can be easily transferred from the collection kit 10 to the two culture bottles 90 and 92.

[0090] Even if the first adapter 21a and the second adapter 21b are provided with the rubber cover 84 covering the needle portion 82 of the first adapter 21a and the second adapter 21b, the first culture bottle 90 and the second culture bottle 92 will not fall off the first adapter 21a and the second adapter 21b due to the elastic repulsive force of the rubber stopper 93.

[0091] The kit holder 102 includes a base 114 fixed to the lifting mechanism 112 and a plurality of holding pins 116 protruding from the base 114 and insertable into holding holes 14h formed in the collection bag 14 of the collection kit 10. Therefore, the collection kit 10 can be held with a simple structure.

[0092] The collecting bag 14 has four corners 14a arranged to surround the first storage chamber 26 and the second storage chamber 28. The plurality of holding pins 116 has four holding pins 116 for holding the four corners 14a of the collecting bag 14. With this configuration, the collecting bag 14 can be stably held.

[0093] The kit holding part 102 has a base part 114 fixed to the lifting mechanism 112. The first adapter supporting part 104 has a pair of first protrusions 105 protruding from the base part 114 and separated from each other in the horizontal direction, and the first adapter 21a is sandwiched between the pair of first protrusions 105. The second adapter supporting part 106 has a pair of second protrusions 107 protruding from the base part 114 and separated from each other in the horizontal direction, and the second adapter 21b is sandwiched between the pair of second protrusions 107. With this configuration, the first adapter 21a and the second adapter 21b are well positioned, so that the first adapter 21a and the second adapter 21b can be smoothly connected to the first culture bottle 90 and the second culture bottle 92.

[0094] The collection bag 14 has a tubular portion 31 forming the middle portion 30d of the connection flow path 30, and the kit holder 102 has a clamping portion 118 that closes the connection flow path 30 when the tubular portion 31 is inserted. With this configuration, it is not necessary to attach a separate clamp to the collection kit 10.

[0095] The clamping portion 118 has a V-shaped clamping groove 120 with its apex facing downward. By inserting the tubular portion 31 of the collecting bag 14 into the V-shaped clamping groove 120 from above the clamping portion 118, the connecting flow path 30 can be easily and reliably closed.

[0096] The above-mentioned collection kit clamp 100 can also be used to Figure 6 The collection kit 10A according to the other configuration shown is connected to the first culture bottle 90 and the second culture bottle 92. The collection kit 10A and Figure 2 The collection kit 10 shown is different in that it also has a stand 170 for holding the collection bag 14 .

[0097] The support 170 has a structure for sandwiching the collection bag 14 from the thickness direction. The support 170 sandwiches the collection bag 14 from the thickness direction, thereby maintaining the shape of the collection bag 14 formed of a soft raw material. The support 170 maintains the planar shape of the collection bag 14, thereby improving the operability of the collection kit 10A. In addition, the support 170 prevents the volume change caused by the deformation of the first receiving chamber 26 and the second receiving chamber 28, and suppresses the deviation of the introduced amount of the platelet preparation. The four corners of the support 170 are provided with holding holes 170h. When the kit holding part 102 holds the collection kit 10A, the holding pin 116 is inserted into the holding hole 170h.

[0098] Next, Figure 7 A collection kit jig 200 according to the second embodiment shown will be described.

[0099] The collection kit jig 200 includes: a kit holding portion 202 ; a first adapter support portion 104A; a second adapter support portion 104B; a first bottle fixing portion 108 ; a second bottle fixing portion 110 ; and a lifting mechanism 420 .

[0100] The kit holder 202 is configured to hold the collection kit 10B having the collection bag 14 and the bracket 174. The bracket 174 includes: a main wall portion 180 facing the collection bag 14; and a peripheral wall portion 182 protruding from the outer periphery of the main wall portion 180 in the thickness direction of the main wall portion 180. The inlet pipe 12 is held in the fitting hole 184 provided in the upper part of the peripheral wall portion 182. The exhaust pipe 20a of the exhaust valve 20 (see Figure 2 ) is held in the positioning hole 186 provided in the upper part of the peripheral wall portion 182. It should be noted that, although the details are not shown in the figure, the first sealing member 16 and the second sealing member 18 (see Figure 2 ) are respectively retained in two engaging holes provided at the lower portion of the peripheral wall portion 182.

[0101] Two first support plates 402 are vertically provided on the upper surface of the base 101 of the collection kit clamp 200. The two first support plates 402 are arranged in parallel with each other and are arranged at the left and right ends of the base 101. The base portion 214 is positioned and fixed on the front surface of the upper portion of the first support plate 402. Therefore, the kit holding portion 202 is positioned and fixed above the first bottle fixing portion 108 and the second bottle fixing portion 110.

[0102] The kit holding portion 202 has a plurality of holders (holders) for holding the bracket 174. Specifically, the plurality of holders include a first holder 216A and a second holder 216B. The first holder 216A and the second holder 216B are provided on the front surface 214a of the base portion 214, protrude forward from the front surface 214a, and extend in the vertical direction.

[0103] The first holder 216A holds the right end of the bracket 174. The first holder 216A has a cover 222 for opening and closing the upper part of the first holder 216A. The cover 222 is rotatably connected to the main body of the first holder 216A via a hinge 224. The first holder 216A has a stopper 226 for locking the cover 222 in the closed position.

[0104] The second holder 216B holds the left end of the bracket 174. The second holder 216B is basically configured similarly to the first holder 216A. Therefore, in the second holder 216B, the same names and reference numerals are used for the same components as those of the first holder 216A.

[0105] The front surface 214a of the base 214, the first holder 216A, and the second holder 216B form a storage space 228. The holder 174 is stored in the storage space 228 in a state where it holds the collection bag 14 to form the collection kit 10B.

[0106] The kit holding portion 202 further includes a clamping portion 404. The clamping portion 404 includes: a U-shaped stay 406 connected to the base portion 214; and a roller 408 rotatably supported by the U-shaped stay 406. The roller 408 connects the connecting flow path 30 (see Figure 2 ) is flattened. As a result, the first receiving chamber 26 and the second receiving chamber 28 (see Figure 2 ) is blocked.

[0107] The first adapter support portion 104A and the second adapter support portion 104B are arranged in the horizontal direction at the same height. The first adapter support portion 104A is provided in the kit holding portion 202, and supports the first adapter 21a. The first adapter support portion 104A is a pin member protruding from the front surface 214a of the base portion 214. The second adapter support portion 104B is provided in the kit holding portion 202, and supports the second adapter 21b. The second adapter support portion 104B is a pin member protruding from the front surface 214a of the base portion 214.

[0108] The lifting mechanism 420 moves the first bottle fixing part 108 and the second bottle fixing part 110 in the up-down direction. The lifting mechanism 420 includes a lifting operation part 422 , a first displacement part 430 , a first guide part 450 , a second displacement part 470 , a second guide part 482 , and a gear mechanism 490 .

[0109] Two second support plates 410 are erected on the base 101. The lifting operation part 422 is provided on the front surface of the upper part of the two second support plates 410. The lifting operation part 422 has a support shaft 336, an operating rod 324, two V-shaped arms 326, and a connecting rod 328. In more detail, a rod mounting plate 330 is fixed to the front surface of the upper part of the two second support plates 410. A guide bracket 332 is provided on the front surface of the rod mounting plate 330. The guide bracket 332 has two support guide parts 334 bent forward from the width direction. The support shaft 322 is supported by the two support guide parts 334. The support shaft 322 passes through the through hole of the operating rod 324. The operating rod 324 can rotate around the support shaft 322.

[0110] The operating rod 324 is substantially V-shaped. The operating rod 324 is connected to the first moving plate 432 of the first displacement unit 430 via two V-shaped arms 326 and a connecting rod 328. The upper ends of the two V-shaped arms 326 are connected to the V-shaped curved portion of the operating rod 324. The lower ends of the two V-shaped arms 326 are connected to the upper portion of the connecting rod 328.

[0111] The first displacement unit 430 includes a first moving plate 432 and a first driving plate 434. The first moving plate 432 and the first driving plate 434 are integrally moved up and down. The first guide unit 450 guides the first moving plate 432 and the first driving plate 434 to move up and down.

[0112] The first movable disk 432 is a plate-shaped member extending in the width direction, and a plate nut 436 is arranged substantially in the center in the width direction. The external thread portion 328a of the connecting rod 328 is screwed with the internal thread of the plate nut 436. The first movable disk 432 has a first insertion hole 438 at the left end and the right end. The cylindrical portion 440b of the first stopper 440 passes through the first insertion hole 438. The first stopper 440 is connected to the first movable disk 432 in a state where the upper surface of the large-diameter flange portion 440a of the first stopper 440 abuts against the lower surface of the first movable disk 432.

[0113] Two first guide rods 452 constituting the first guide portion 450 are erected on the base 101. The two first guide rods 452 are respectively passed through the second insertion holes 454 of the first stopper 440. The upper portion of each of the two first guide rods 452 is exposed from the second insertion holes 454. A second stopper 456 is provided at the upper end of each of the two first guide rods 452.

[0114] The first guide rod 452 passes through the first return spring 458. The lower end of the first return spring 458 abuts against the upper surface of the first stopper 440. The upper end of the first return spring 458 abuts against the lower surface of the second stopper 456. The first return spring 458 urges the first movable plate 432 downward via the first stopper 440.

[0115] The second displacement unit 470 has a second movable plate 472 that can be raised and lowered. The first bottle fixing unit 108 and the second bottle fixing unit 110 are respectively composed of a first container holder 207A and a second container holder 207B provided on the upper surface of the second movable plate 472. The first container holder 207A and the second container holder 207B are raised and lowered integrally with the second movable plate 472. A scale 91 for measurement is provided on the side surface of the first culture bottle 90 and the side surface of the second culture bottle 92. Figure 1 The bottle fixing member 122 shown replaces the first container holder 207A and the second container holder 207B.

[0116] exist Figure 7 In the figure, the second movable plate 472 has a third insertion hole (not shown) at the left end and the right end. The third insertion hole extends in the up-down direction. On the upper surface of the second movable plate 472, a third stopper 474 is provided at the left end and the right end. The third stopper 474 has a fourth insertion hole 478 overlapping with the upper part of the third insertion hole. The second drive plate 480 is fixed to the second movable plate 472. Therefore, the second movable plate 472 and the second drive plate 480 are lifted and lowered integrally.

[0117] Two second guide rods 484 constituting the second guide portion 482 are erected on the base 101. The two second guide rods 484 are respectively passed through the third insertion hole and the fourth insertion hole 478. The upper portion of each of the two guide rods 362 is exposed from the fourth insertion hole 478. A fourth stopper 486 is provided at the upper end of each of the two guide rods 362.

[0118] The second guide rod 484 passes through the inside of the second return spring 488. The lower end of the second return spring 488 abuts against the upper surface of the third stopper 474. The upper end of the second return spring 488 abuts against the lower surface of the fourth stopper 486. The second return spring 488 urges the second movable plate 472 downward via the fourth stopper 486.

[0119] The gear mechanism 490 includes a first rack 492, a second rack 494, and a pinion 496 meshing with the first rack 492 and the second rack 494. The first rack 492 is fixed to the first drive plate 434. The second rack 494 is fixed to the second drive plate 480. The pinion 496 is interposed between the first rack 492 and the second rack 494. The pinion 496 is rotatably supported by an L-shaped stay 498 erected on the upper surface of the base 101 via a bearing 500.

[0120] The collection kit clamp 200 constructed as described above is used in the following manner.

[0121] The user sets the collection kit 10B containing the collection object on the kit holding portion 202 of the collection kit clamp 200. When setting, the cover 222 is closed and the cover 222 is locked in the closed position by the stopper 226. As the collection kit 10B is set on the kit holding portion 202, the clamping portion 404 presses the connecting flow path 30 (see Figure 2 ). Thus, the first storage chamber 26 and the second storage chamber 28 (see Figure 2 ) is blocked.

[0122] Next, the user performs an operation for transferring the collection object from the collection kit 10B to the first culture bottle 90 and the second culture bottle 92. Specifically, the user holds one end of the operation rod 324 and moves the end toward Figure 7 In order to lower the connection rod 328 in the A direction, the operation rod 324 is rotated. As a result, the connection rod 328 is lowered.

[0123] The external thread portion 328a of the connecting rod 328 is connected to the first moving plate 432 via the plate nut 436, and the first driving plate 434 is connected to the first moving plate 432. Therefore, as the connecting rod 328 descends, the first moving plate 432 and the first driving plate 434 descend integrally.

[0124] When the first moving disk 432 and the first driving plate 434 are lowered, the pinion 496 is pushed downward by the first rack 492 and rotates. As a result, the second rack 494 is pushed upward by the pinion 496. Thus, the second driving plate 480 and the second moving disk 472 connected thereto are raised integrally.

[0125] When the second moving plate 472 rises, the second return spring 488 disposed between the third stopper 474 and the fourth stopper 486 is compressed in the axial direction. That is, the second moving plate 472 rises against the elastic force of the second return spring 488.

[0126] The first bottle fixing part 108 and the second bottle fixing part 110 are raised integrally with the second moving plate 472. As a result, the first culture bottle 90 is connected to the first adapter 21a, and the second culture bottle 92 is connected to the second adapter 21b. Thereafter, the first sealing member 16 and the second sealing member 18 (see Figure 2 Along with this, the collected object is introduced into the first culture bottle 90 and the second culture bottle 92.

[0127] Next, the user rotates the operating rod 324 so that one end of the operating rod 324 rises. As a result, the second return spring 488 is released from the force compressing the second return spring 488 upward. Therefore, the second return spring 488 is extended due to elasticity. In conjunction with this, the second return spring 488 applies force downward to the second movable plate 472 via the third stopper 474. As a result, the second movable plate 472, the first bottle fixing portion 108, and the second bottle fixing portion 110 are integrally lowered. With the lowering of the first bottle fixing portion 108 and the second bottle fixing portion 110, the first adapter 21a is removed from the first culture bottle 90, and the second adapter 21b is removed from the second culture bottle 92. Through the above steps, the collection (sampling) of the collection object to the first culture bottle 90 and the second culture bottle 92 using the collection kit 10B is completed.

[0128] It should be noted that, as the second moving plate 472 descends, the second rack 494 pushes the pinion 496 downward, and the pinion 496 pushes the first rack 492 upward, in a reverse manner to the above. As a result, the first drive plate 434 and the first moving plate 432 ascend and return to their original positions.

[0129] Next, Figure 8 A collection kit jig 300 according to the third embodiment shown will be described.

[0130] The collection kit uses a clamp 300 to Figure 7 The collection kit jig 200 according to the second embodiment shown has a configuration in which the kit holding portion 202 is replaced with a kit holding portion 602 .

[0131] exist Figure 8 , the kit holding portion 602 includes a base portion 614, a first holder 620A, a second holder 620B, a cover 640, a first adapter support portion 104A, and a second adapter support portion 104B. The first holder 620A is disposed at the right portion of the base portion 614, and the second holder 620B is disposed at the left portion of the base portion 614. The front surface 614a of the base portion 614, the first holder 620A, and the second holder 620B form a storage space 622 for storing the bracket 174.

[0132] A stopper 628 is provided at the left end of the cover 640. A hinge 634 is connected to the right end of the cover 640. The cover 640 can rotate via the hinge 634 fixed to the first retainer 620A. A hook 630 for fixing the stopper 628 is provided on the second retainer 620B. The cover 640 is preferably transparent or translucent. In this case, the user can visually identify the collection bag 14 through the cover 640.

[0133] The cover 640 is provided with a clamping portion 642. When the cover 640 is in a closed state, the clamping portion 642 flattens the connecting flow path 30 in the collection bag 14, thereby blocking the communication between the first storage chamber 26 and the second storage chamber 28.

[0134] The kit holder 602 has a plurality of holding pins 624 protruding from the front surface 614a of the base 614. The plurality of holding pins 624 are respectively engaged with four holding holes provided in the bracket 174 of the collection kit 10B. With this configuration, the collection kit 10B can be positioned and fixed to the kit holder 602 with a simple structure.

[0135] An exhaust valve shielding portion 650 and a pipe supporting portion 654 are provided on an upper portion of a front surface 614 a of the base portion 614 .

[0136] The exhaust valve shielding portion 650 is a surrounding portion having a top portion 652. The top portion 652 covers the upper portion of the exhaust valve 20. The upper surface of the exhaust valve 20 and the lower surface of the top portion 652 are slightly separated from each other. Thus, the exhaust valve 20 is prevented from being closed by the top portion 652. The exhaust valve shielding portion 650 can suppress the flow of atmospheric air into the second accommodation chamber 28 via the exhaust valve 20.

[0137] The tube support portion 654 has a pair of protrusions 656 protruding forward. The inflow tube 12 of the collection kit 10B is sandwiched between the pair of protrusions 656. Thus, the inflow tube 12 is supported by the tube support portion 654.

[0138] The collection kit clamp 300 constructed as described above is used in the following manner.

[0139] The user opens the cover 640 and inserts the bracket 174 into the storage space 622. At this time, the four holding pins 624 of the kit holding portion 602 are respectively engaged with the four holding holes provided in the bracket 174. Thus, the collection kit 10B is fixed (held) to the kit holding portion 602.

[0140] Next, the user rotates the cover 640 to close the cover 640, and fixes the stopper 628 to the hook 630. Thus, the cover 640 is maintained in the closed state.

[0141] The operation of transferring the collection object from the collection kit 10B to the first culture bottle 90 and the second culture bottle 92 is the same as that of the second embodiment.

[0142] Next, Fig. 9 A collection kit jig 400 according to a fourth embodiment will be described.

[0143] The kit holding portion 102 of the collection kit jig 400 is Figure 1 The kit holding portion 102 of the collection kit clamp 100 shown is similarly constructed. Fig. 9 In the illustrated collection kit jig 400 , the base portion 114 of the kit holding portion 102 is fixed to the upper portions of two support plates 403 erected on the base 101 .

[0144] The lifting mechanism 610 of the collection kit clamp 400 moves the first bottle fixing portion 108 and the second bottle fixing portion 110 in the vertical direction relative to the kit holding portion 102. Figure 1 A portion of the lifting mechanism 112 shown is Figure 7 The structure is obtained by combining a part of the lifting mechanism 420 shown in FIG. Fig. 9 In the lifting mechanism 610 shown in FIG. Figure 1 The lifting mechanism 112 and Figure 7 The same components of the lifting mechanism 420 shown are denoted by the same reference numerals.

[0145] exist Fig. 9 In the embodiment, the lifting mechanism 610 of the collection kit clamp 400 includes: a frame 126 fixed to the base 101; a displacement portion 128 (hereinafter referred to as "first displacement portion 128") supported by the frame 126 in a liftable manner; and a lifting operation portion 130 mounted on the frame 126. The first drive plate 434 is connected to the support body 142 of the displacement portion 128.

[0146] The lifting mechanism 610 includes a second displacement unit 470. The second displacement unit 470 includes a second moving plate 472 that supports the first bottle fixing unit 108 and the second bottle fixing unit 110, and a second driving plate 480 connected to the second moving plate 472. Fig. 9 Although not shown in the figure, a first drive plate 434 and a second drive plate 480 are provided between them. Figure 7 Gear mechanism 490 is shown.

[0147] When the user moves the lifting operation unit 130 from Fig. 9 When the state shown in FIG. 1 is rotated in the direction A, the support body 142 of the first displacement portion 128 descends. The descending of the support body 142 is achieved by the gear mechanism 490 (see FIG. 4 ). Figure 7 ) is converted into the rise of the second drive plate 480. With the rise of the second drive plate 480, the second movable plate 472 rises, and the first culture bottle 90 and the second culture bottle 92 supported by the first bottle fixing part 108 and the second bottle fixing part 110, respectively, rise. As a result, the first culture bottle 90 is connected to the first adapter 21a, and the second culture bottle 92 is connected to the second adapter 21b.

[0148] After the transfer of the collected object to the first culture bottle 90 and the second culture bottle 92 is completed, if the user rotates the lifting operation unit 130 in the direction opposite to the direction A, the first culture bottle 90 and the second culture bottle 92 are lowered. As a result, the first adapter 21a is removed from the first culture bottle 90, and the second adapter 21b is removed from the second culture bottle 92.

[0149] Other possible modifications are briefly described below.

[0150] exist Figure 1 In the first embodiment shown in the figure, the kit holding portion 102 may be replaced with a Figure 7 The kit holding unit 202 shown in the figure holds the collection kit 10B in the kit holding unit 202. Figure 1 In the first embodiment shown in the figure, the clamping portion 118 may be replaced by Figure 7 The clamping portion 404 is shown. Figure 1 In the first embodiment shown in the figure, the kit holding portion 102 may be replaced with a Figure 8 The kit holding unit 602 shown in the figure holds the collection kit 10B in the kit holding unit 602. Figure 7 In the second embodiment shown in the figure, the kit holding portion 202 may be replaced with a Figure 1 The kit holder 102 is shown. Figure 8 In the third embodiment shown in the figure, the kit holding portion 602 may be replaced with a Figure 1 The kit holder 102 is shown. Fig. 9 In the fourth embodiment shown in the figure, the lifting mechanism 610 may be replaced by a Figure 7 The lifting mechanism 420 shown in the figure. In this way, the components of the first embodiment to the fourth embodiment can be replaced with each other.

[0151] In the first to fourth embodiments, the kit holding portion 102, 202, 602 is raised and lowered relative to the first bottle fixing portion 108 and the second bottle fixing portion 110 by the user operating the operating lever 158, 324. Instead, the kit holding portion 102, 202, 602 may be raised and lowered relative to the first bottle fixing portion 108 and the second bottle fixing portion 110 using an actuator such as a ball screw or a motor.

[0152] In the first to fourth embodiments, the collection kit clamp may include a plurality of kit holding sections. In this case, when the user operates one operating lever, all the kit holding sections are simultaneously raised and lowered relative to the first bottle fixing section 108 and the second bottle fixing section 110 .

[0153] The first electronic balance, the second electronic balance, the first weight display unit, and the second weight display unit mentioned in association with the first embodiment may also be provided in Figure 7 to Figure 9 In the case of the collection kit jigs 200 , 300 , and 400 according to the second to fourth embodiments, the first electronic balance and the second electronic balance may be provided on the second moving plate 472 , for example.

[0154] Specifically, the second movable plate 472 includes: a main body provided on the first electronic balance and the second electronic balance; and a sliding rack portion that can be pulled forward relative to the main body. The sliding rack portion is located directly below the first container holder 207A and the second container holder 207B, and shields the first electronic balance and the second electronic balance when stored in the main body. On the other hand, when the sliding rack portion is pulled out from the main body, the first electronic balance and the second electronic balance are exposed. In addition, through holes are formed at the bottom of the first container holder 207A and the second container holder 207B.

[0155] In this configuration, when transferring the collection object from the first storage chamber 26 and the second storage chamber 28 of the collection bag 14 to the first culture bottle 90 and the second culture bottle 92, respectively, the slide rack is pulled forward relative to the main body. In conjunction with this, the bottom of the first culture bottle 90 and the bottom of the second culture bottle 92 come into contact with the first electronic balance and the second electronic balance through the through hole, respectively. As a result, the weight of the collection object in the first culture bottle 90 and the weight of the collection object in the second culture bottle 92 are measured separately.

[0156] It should be noted that the present invention is not limited to the above-mentioned disclosure, and various configurations can be adopted without departing from the gist of the present invention.

Claims

1. A collection kit clamp, which is a collection kit clamp for connecting the collection kit to a culture bottle, The collection kit comprises: an inflow tube connected to a medical bag containing a collection object; a collection bag connected downstream of the inflow tube, having a first receiving chamber and a second receiving chamber and having a connecting flow path connecting the first receiving chamber and the second receiving chamber; a first outflow port connected to the first receiving chamber; a second outflow port connected to the second receiving chamber; a first adapter connected downstream of the first outflow port and capable of being connected to a first culture bottle; and a second adapter connected downstream of the second outflow port and capable of being connected to a second culture bottle. The clamp for the collection kit comprises: A kit holding portion, which holds the collection kit; a first adapter support portion, which is provided on the kit holding portion and supports the first adapter; a second adapter support portion, which is provided on the kit holding portion and supports the second adapter; a first bottle fixing portion, which is disposed below the kit holding portion and fixes the first culture bottle; a second bottle fixing portion disposed below the kit holding portion and fixing the second culture bottle; and The lifting mechanism moves the kit holding portion relative to the first bottle fixing portion and the second bottle fixing portion in the up-down direction.

2. The clamp for the collection kit according to claim 1, wherein: The kit holding portion has: A base portion fixed to the lifting mechanism; and A plurality of retaining pins protrude from the base portion, and the retaining pins can be inserted into retaining holes formed in the collection bag of the collection kit.

3. The clamp for the collection kit according to claim 2, wherein: The collecting bag has four corners arranged to surround the first storage chamber and the second storage chamber. The plurality of holding pins include four holding pins for holding the four corners of the collecting bag.

4. The clamp for the collection kit according to claim 1, wherein: The kit holding portion has a base portion fixed to the lifting mechanism, The first adapter support portion includes a pair of first protrusions that protrude from the base portion and are separated from each other in a horizontal direction, and the first adapter is clamped between the pair of first protrusions. The second adapter support portion includes a pair of second protrusions that protrude from the base portion and are separated from each other in a horizontal direction, and sandwiches the second adapter between the pair of second protrusions.

5. The clamp for a collection kit according to any one of claims 1 to 4, wherein: The collecting bag has a tubular portion forming a middle portion of the connecting flow path, The kit holding portion has a clamping portion that closes the connection flow path when the tubular portion is inserted.

6. The clamp for the collection kit according to claim 5, wherein: The clamping portion has a V-shaped clamping groove with its apex facing downward.

7. The clamp for a collection kit according to any one of claims 1 to 4, wherein: The lifting mechanism moves the kit holding portion in the up-down direction.

8. The clamp for a collection kit according to any one of claims 1 to 4, wherein: The lifting mechanism moves the first bottle fixing portion and the second bottle fixing portion in a vertical direction.

Images