Composition for cleaning hair

Abstract

A composition for cleansing hair comprises: a) at least one alpha-hydroxy acid; b) at least one nonionic surfactant selected from alkyl (poly) glycosides; c) at least one cationic surfactant selected from fatty amido amines; and d) a solvent.

Description

Technical Field The present invention relates to cosmetic compositions. In particular, it relates to compositions for cleaning hair and methods of cleaning hair using the compositions. Background Art Oily scalp and hair are becoming an annoying scalp problem worldwide. People often use oil-control shampoos to remove dirt and sebum from the scalp.

[0003] There are many shampoos that are developed to cleanse the hair and scalp.

[0004] For example, US9018150B1 discloses a cleaning composition comprising from about 6% to about 20% of at least one nonionic surfactant; from about 3% to about 10% of at least one amphoteric surfactant; from about 2% to about 8% of at least one anionic surfactant; and from about 0.1% to about 5% of at least one cationic conditioning surfactant, a cationic conditioning amine, or a combination thereof; wherein the amount of the nonionic surfactant present in the final composition is greater than the amount of the amphoteric surfactant, and based on the weight percentage of each surfactant in the final composition, the ratio of the nonionic surfactant (a) to the anionic surfactant (c) is at least about 1.9 times that of the anionic surfactant.

[0005] However, with most commercially available shampoos, consumers are not satisfied with the long-lasting cleansing between washes. To achieve good long-lasting cleansing performance, most commercially available shampoos contain large amounts of surfactants and exfoliants as cleansing agents to remove stubborn sebum and dead cells. Large amounts of surfactants and exfoliants in shampoos bring about irritation problems that cause dryness, itching, redness, and even stinging sensations on the scalp.

[0006] Therefore, consumers are still seeking optimal cleansing compositions that provide adequate long-lasting cleansing while reducing scalp irritation issues. SUMMARY OF THE INVENTION It was therefore an object of the present invention to develop compositions for cleaning the hair which provide a sufficient and long-lasting cleaning effect and which at the same time cause fewer irritation problems to the scalp.

[0008] Another object of the present invention is to provide a method for cleaning hair.

[0009] Thus, according to a first aspect, the present invention provides a composition for cleansing hair comprising: a) at least one hydroxy acid; b) at least one nonionic surfactant selected from alkyl (poly)glycosides; c) at least one cationic surfactant selected from fatty amidoamines and salts thereof corresponding to the following formula (I): RCONHR″N(R′)2 (I) wherein R is a linear or branched non-cyclic alkyl or alkenyl group containing 16 to 22 carbon atoms; R" is a divalent hydrocarbon radical containing less than 6 carbon atoms, and R, which may be the same or different, represents a hydrocarbon group containing less than 6 carbon atoms; and d) Solvent.

[0010] According to a second aspect, the present invention provides a method for cleansing hair comprising applying to the hair a composition as described above and subsequently rinsing the hair with water after any exposure period.

[0011] The inventors have found that compositions according to the invention can provide a long-lasting cleansing effect with reduced scalp irritation.

[0012] Other objects and features, aspects and advantages of the invention will appear even more clearly on reading the detailed description and examples which follow. DETAILED DESCRIPTION OF THE INVENTION Unless otherwise indicated, the upper and lower limits of a numerical range as used herein are included in the range, especially in the expressions "between ... and ..." and "... to ...".

[0014] As used herein, the term "comprising" should be interpreted as covering all the specifically mentioned features as well as optional, additional, unspecified features.

[0015] As used herein, use of the term "comprising" also discloses embodiments in which features other than those specifically mentioned are absent (ie, "consisting of.").

[0016] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by those skilled in the art to which the invention belongs. When the definition of a term in this specification conflicts with the meaning commonly understood by those skilled in the art to which the invention belongs, the definition described herein shall apply.

[0017] Unless otherwise indicated, all numerical values ​​expressing quantities of ingredients and so forth used in the specification and claims are to be understood as modified by the term “about.” Accordingly, unless indicated to the contrary, the numerical values ​​and parameters described herein are approximations that can vary depending upon the desired properties as required to be obtained.

[0018] As used herein, the expression "at least one" used in this specification is equivalent to the expression "one or more".

[0019] According to a first aspect of the present invention, a composition for cleaning hair comprises: a) at least one hydroxy acid; b) at least one nonionic surfactant selected from alkyl (poly)glycosides; c) at least one cationic surfactant selected from fatty amidoamines and salts thereof corresponding to the following formula (I): RCONHR″N(R′)2 (I) wherein R is a linear or branched non-cyclic alkyl or alkenyl group containing 16 to 22 carbon atoms; R" is a divalent hydrocarbon radical containing less than 6 carbon atoms, and R, which may be the same or different, represents a hydrocarbon group containing less than 6 carbon atoms; and d) Solvent.

[0020] Hydroxy Acid The composition according to the invention comprises at least one hydroxy acid. The hydroxy acid may be selected from alpha-hydroxy acids and / or beta-hydroxy acids. Preferably, the at least one hydroxy acid is a combination of an alpha-hydroxy acid and a beta-hydroxy acid.

[0021] Alpha Hydroxy Acids According to the present invention, the term "alpha-hydroxy acid" is understood to mean a carboxylic acid having at least one hydroxyl function occupying the alpha position (the carbon adjacent to the carboxylic acid function) on the acid.

[0022] Suitable alpha-hydroxy acids include glycolic acid, citric acid, lactic acid, methyllactic acid, glucuronic acid, pyruvic acid, 2-hydroxybutyric acid, 2-hydroxyvaleric acid, 2-hydroxyhexanoic acid, 2-hydroxyheptanoic acid, 2-hydroxyoctanoic acid, 2-hydroxynonanoic acid, 2-hydroxydecanoic acid, 2-hydroxyundecanoic acid, 2-hydroxydodecanoic acid, 2-hydroxytetradecanoic acid, 2-hydroxyhexadecanoic acid, 2-hydroxyoctadecanoic acid, 2-hydroxytetracosanoic acid, 2-hydroxyeicosanoic acid, mandelic acid, phenyllactic acid, gluconic acid, galacturonic acid, eleuric acid, ribonic acid, tartronic acid, tartaric acid, malic acid, and fumaric acid.

[0023] Preferably, the alpha-hydroxy acid is selected from lactic acid, glycolic acid, tartaric acid, mandelic acid, citric acid, and combinations thereof.

[0024] More preferably, the alpha-hydroxy acid in the composition consists of lactic acid.

[0025] Lactic acid or 2-hydroxypropionic acid provides gentle exfoliation of excess sebum, residues and loose dead cells around follicles, and makes the hair roots strong and erect. In addition, lactic acid also promotes the production of mucopolysaccharides (GAGs) in the skin, improving the skin's barrier function and moisturizing.

[0026] Advantageously, the alpha-hydroxy acid is present in an amount ranging from 0.1 wt.% to 30 wt.%, preferably from 0.5 wt.% to 20 wt.% and more preferably from 1.5 wt.% to 10 wt.% relative to the total weight of the composition.

[0027] Beta-Hydroxy Acids According to the invention, the term "β-hydroxy acid" is understood to mean a carboxylic acid having a hydroxyl function and a carboxyl function separated by two carbon atoms.

[0028] Suitable beta-hydroxy acids include salicylic acid, propionic acid, beta-hydroxybutyric acid, beta-hydroxy beta-methylbutyric acid, carnitine, derivatives thereof, and combinations thereof.

[0029] Preferably, the β-hydroxy acid is selected from salicylic acid and its derivatives of formula (II): wherein R is a linear, branched or cyclic saturated aliphatic group, or an aliphatic unsaturated group containing one or several double bonds which may or may not be conjugated, these groups contain 2 to 22, preferably 3 to 11 carbon atoms, and can be substituted, for example, by at least one substituent selected from the group consisting of: (a) a halogen atom, (b) a trifluoromethyl group, (c) a hydroxyl group in free form or esterified with an acid having 1 to 6 carbon atoms, or (d) a free carboxyl function or a carboxyl function esterified with a lower alcohol having 1 to 6 carbon atoms; R is a hydroxyl group or an ester functional group of the following formula (III): wherein R1 is a straight or branched saturated or unsaturated aliphatic group having 1 to 18 carbon atoms.

[0030] Preferred salicylic acid derivatives include 5-n-octanoylsalicylic acid (octanoylsalicylic acid), 5-n-decanoylsalicylic acid, 5-n-dodecanoylsalicylic acid, 5-n-heptyloxysalicylic acid and 4-n-heptyloxysalicylic acid.

[0031] More preferably, the β-hydroxy acid is selected from salicylic acid, 5-n-octanoyl salicylic acid, 5-n-decanoyl salicylic acid, 5-n-dodecanoyl salicylic acid, 5-n-heptyl salicylic acid, 4-n-heptyl salicylic acid, and combinations thereof.

[0032] Most preferably, the beta-hydroxy acid is salicylic acid.

[0033] Salicylic acid or 2-hydroxybenzoic acid is provided to the chemical peel composition to provide enhanced penetration of the composition into the skin. Salicylic acid penetrates deeper into the skin than alpha-hydroxy acids such as lactic acid.

[0034] Advantageously, the beta-hydroxy (acid) is present in an amount ranging from 0.1 wt.% to 30 wt.%, preferably from 0.5 wt.% to 15 wt.% and more preferably from 1 wt.% to 8 wt.% relative to the total weight of the composition.

[0035] According to one embodiment, the composition of the invention contains at least one alpha-hydroxy acid and at least one beta-hydroxy acid. In this case, the alpha-hydroxy acid is present in an amount of 0.1 to 30% by weight and the beta-hydroxy acid is present in an amount of 0.1 to 30% by weight, based on the total weight of the composition. And the ratio of alpha-hydroxy acid to beta-hydroxy acid is 0.5 to 30, preferably 1 to 15, and more preferably 2 to 10. Preferably, the alpha-hydroxy acid is chosen from lactic acid and the beta-hydroxy acid is chosen from salicylic acid.

[0036] The inventors have found that the composition according to the invention, in particular when the composition contains both alpha-hydroxy acid and beta-hydroxy acid, in particular lactic acid and salicylic acid or derivatives thereof, can effectively remove stubborn sebum. Thus, the combination of surfactant and hydroxy acid provides even better long-lasting cleaning effect.

[0037] Alkyl (poly) glycosides The composition according to the invention comprises at least one nonionic surfactant chosen from alkyl (poly)glycosides.

[0038] As used herein, the term "alkyl (poly)glycoside" refers to alkyl glycosides and polyalkyl glycosides as well as polyglycosides.

[0039] Alkyl and polyalkyl glycosides or polyglycosides which may be used include, for example, those containing an alkyl group containing 6 to 30 carbon atoms, preferably 6 to 18 or even 8 to 16 carbon atoms, and containing a glycosidic group containing preferably 1 to 5, for example 1, 2 or 3 glycosidic units.

[0040] In certain embodiments, the composition comprises at least one alkyl polyglycoside having the following formula (XI): R1O-(R2O) t -(G) v (IV) in: R1 represents a linear or branched alkyl or alkenyl group containing 6 to 30, for example 8 to 24, preferably 8 to 18 carbon atoms, or an alkylphenyl group in which the alkyl group is linear or branched and contains 8 to 24 carbon atoms; R2 represents an alkylene group containing about 2 to 4 carbon atoms; G represents a sugar unit containing 5 or 6 carbon atoms, preferably glucose, fructose or galactose; t is a number ranging from 0 to 10, preferably from 0 to 4, more preferably from 0 to 3; and v is a number ranging from 1 to 15.

[0041] Non-limiting examples of useful alkyl (poly)glycosides include lauryl glucoside, octyl glucoside, decyl glucoside, coco-glucoside, octyl / decyl glucoside and sodium lauryl glucose carboxylate.

[0042] In certain embodiments, the at least one alkyl polyglycoside compound is selected from lauryl glucoside, decyl glucoside, cocoyl glucoside, and combinations thereof.

[0043] In a preferred embodiment, the composition comprises decyl glucoside.

[0044] In various embodiments, the total amount of alkyl (poly)glycosides ranges from about 0.1 wt.% to about 20 wt.%, preferably from about 1 wt.% to about 12 wt.%, more preferably from about 2 wt.% to about 8 wt.%, relative to the total weight of the composition.

[0045] Fatty amide amine cationic surfactant The composition according to the invention comprises at least one cationic surfactant chosen from fatty amidoamines and their salts corresponding to the following formula (Ia): RCONHR″N(R′)2(I) wherein R is a linear or branched non-cyclic alkyl or alkenyl group containing 16 to 22 carbon atoms; R" is a divalent hydrocarbon radical containing less than 6 carbon atoms, and R may be the same or different and represent a hydrocarbon group containing less than 6 carbon atoms.

[0046] Preferably, R" is a divalent hydrocarbon group containing 2 or 3 carbon atoms.

[0047] Preferably, the groups R may be identical or different, linear or branched, saturated or unsaturated, substituted or unsubstituted. More preferably, the group R is a methyl group.

[0048] Non-limiting examples include oleamidopropyl dimethylamine, stearamidopropyl dimethylamine, isostearamidopropyl dimethylamine, stearamidoethyl dimethylamine, behenamidopropyl dimethylamine, palmitamidopropyl dimethylamine, rapeamidopropyl dimethylamine, stearamidoethyl diethylamine, and combinations thereof.

[0049] Preferably, the cationic surfactant is selected from stearamidopropyl dimethylamine, rapeamidopropyl dimethylamine, and combinations thereof.

[0050] Advantageously, the cationic surfactant is present in an amount ranging from 0.1 wt.% to 2 wt.%, preferably from 0.2 wt.% to 1.5 wt.%, more preferably from 0.4 wt.% to 0.8 wt.% relative to the total weight of the composition.

[0051] Anionic surfactants The compositions according to the invention may contain at least one anionic surfactant.

[0052] The term "anionic surfactant" denotes a surfactant which comprises only anionic groups as ionic or ionizable groups.

[0053] In this specification, a species is referred to as "anionic" when it carries at least one permanent negative charge or when it can be ionized into a negatively charged species under the conditions of use of the composition of the invention (e.g., medium or pH) and does not contain any cationic charge.

[0054] The anionic surfactant may be a sulfate surfactant and / or a sulfonate surfactant. It should be understood in this specification that: - sulfonate anionic surfactants comprising at least one sulfonate functional group (-SO3H or -SO3) and optionally also one or more sulfate functional groups, but not any carboxylate functional groups; and -Sulfate anionic surfactants contain at least one sulfate functional group but do not contain any carboxylate or sulfonate functional groups.

[0055] Sulfonate anionic surfactants that can be used contain at least one sulfonate functional group (-SO3H or -SO3).

[0056] They can be chosen from the following compounds: alkyl sulfonates, alkylamide sulfonates, alkylaryl sulfonates, α-olefin sulfonates, paraffin sulfonates, alkyl sulfosuccinates, alkyl ether sulfosuccinates, alkylamide sulfosuccinates, alkyl sulfoacetates, N-acyltaurates, acyl isethionates; alkyl sulfolaurates; and also the salts of these compounds; The alkyl group of these compounds contains 6 to 30 carbon atoms, in particular 12 to 28 carbon atoms, still better still 14 to 24 carbon atoms or even 16 to 22 carbon atoms; aryl preferably denotes phenyl or benzyl; These compounds may be polyoxyalkylenated, in particular polyoxyethylenated, and thus contain preferably 1 to 50 ethylene oxide units and better still 2 to 10 ethylene oxide units.

[0057] Preferably, the sulfonate anionic surfactants are selected, alone or in combination, from: - C6-C24 and in particular C12-C20 alkyl sulfosuccinates, in particular lauryl sulfosuccinate; - C6-C24 and in particular C12-C20 alkyl ether sulfosuccinates; - C6-C24 acyl isethionate, and preferably C12-C18 acyl isethionate, In particular, they are in the form of alkali metal or alkaline earth metal salts, ammonium salts or amino alcohol salts.

[0058] Sulfate ester anionic surfactants that can be used contain at least one sulfate functional group (-OSO3H or -OSO3-).

[0059] They can be selected from the following compounds: alkyl sulfates, alkyl ether sulfates, alkyl amido ether sulfates, alkyl aryl polyether sulfates, monoglycerol sulfates; and also salts of these compounds; The alkyl group of these compounds contains 6 to 30 carbon atoms, in particular 12 to 28 carbon atoms, still better still 14 to 24 carbon atoms or even 16 to 22 carbon atoms; aryl preferably denotes phenyl or benzyl; These compounds may be polyoxyalkylenated, in particular polyoxyethylenated, and thus contain preferably 1 to 50 ethylene oxide units and better still 2 to 10 ethylene oxide units.

[0060] Preferably, the sulfate anionic surfactant is selected from the group consisting of: - C6-C24 alkyl sulfates, and in particular C12-C20 alkyl sulfates; - alkyl ether sulfates, in particular C6-C24 or even C12-C20 alkyl ether sulfates, preferably containing 2 to 20 ethylene oxide units; In particular, they are in the form of alkali metal or alkaline earth metal salts, ammonium salts or amino alcohol salts.

[0061] When the anionic surfactant is in salt form, the salt may be selected from alkali metal salts, such as sodium or potassium salts; ammonium salts; amine salts, and especially amino alcohol salts; and alkaline earth metal salts, such as magnesium salts.

[0062] Examples of aminoalcohol salts that may be mentioned include monoethanolamine, diethanolamine and triethanolamine salts, monoisopropanolamine, diisopropanolamine or triisopropanolamine salts, 2-amino-2-methyl-1-propanol salts, 2-amino-2-methyl-1,3-propanediol salts and tris(hydroxymethyl)aminomethane salts.

[0063] Preference is given to using alkali metal salts or alkaline earth metal salts, and in particular sodium salts or magnesium salts.

[0064] Preferably, the anionic surfactants are selected, alone or in combination, from: - C6-C24 and in particular C12-C20 alkyl sulfates; - C6-C24 and in particular C12-C20 alkyl ether sulfates; preferably containing 2 to 20 ethylene oxide units; - C6-C24 and in particular C12-C20 alkyl sulfosuccinates, in particular lauryl sulfosuccinate; - C6-C24 and in particular C12-C20 alkyl ether sulfosuccinates; - C6-C24 acyl isethionate, and preferably C12-C18 acyl isethionate; In particular, they are in the form of alkali metal salts, such as sodium salts, or alkaline earth metal salts, ammonium salts or amino alcohol salts.

[0065] Preferably, the anionic surfactant is selected from sodium laureth sulfate, sodium lauryl sulfate, and combinations thereof.

[0066] Advantageously, the anionic surfactant is present in an amount ranging from 5 wt.% to 50 wt.%, preferably from 9 wt.% to 25 wt.%, more preferably from 12 wt.% to 18 wt.% relative to the total weight of the composition.

[0067] According to a particular embodiment, the composition of the invention contains an anionic surfactant, preferably a sulfate anionic surfactant as described above.

[0068] Water Phase The composition according to the invention comprises an aqueous phase.

[0069] Preferably, the aqueous phase is the continuous phase.

[0070] The aqueous phase of the present invention comprises water.

[0071] The aqueous phase may also contain a water-miscible organic solvent (at room temperature of 20-25° C.), such as a polyol, such as a C2-C6 polyol, more particularly glycerol, hexylene glycol; glycol ethers (especially containing 3 to 16 carbon atoms), such as monopropylene glycol (C1-C4) alkyl ether, dipropylene glycol (C1-C4) alkyl ether or tripropylene glycol (C1-C4) alkyl ether, monoethylene glycol (C1-C4) alkyl ether, diethylene glycol (C1-C4) alkyl ether or triethylene glycol (C1-C4) alkyl ether, and combinations thereof.

[0072] Advantageously, the aqueous phase is present in an amount ranging from 40 wt.% to 90 wt.%, preferably from 50 wt.% to 80 wt.% relative to the total weight of the composition.

[0073] Additional Ingredients The composition according to the invention may also comprise any other additional ingredients conventionally used in the field of self-cleaning products, especially shampoos.

[0074] The amount of additional ingredients may be selected by a person skilled in the art so as not to adversely affect the end use of the composition according to the invention.

[0075] For example, such additional ingredients include pH adjusters, preservatives, antioxidants, fragrances, electrolytes and stabilizers, plant extracts, proteins, amino acids, vitamins, glycols, emollients, derivatives of the foregoing, and combinations thereof.

[0076] Non-limiting examples of pH adjusters include potassium acetate, potassium hydroxide, sodium carbonate, sodium hydroxide, phosphoric acid, succinic acid, sodium citrate, sodium bicarbonate, triethanolamine, monoethanolamine, diethanolamine, N,N-dimethylethanolamine, and combinations thereof.

[0077] In some embodiments, the pH adjuster is used in an amount such that the pH of the composition of the present invention is less than or equal to 6.5, preferably 2 to 6.5, more preferably 3.5 to 4.5.

[0078] According to a preferred embodiment, the present invention provides a composition for cleaning hair, which comprises, relative to the total weight of the composition: a) 1.5 wt.% to 10 wt.% of lactic acid and 1 wt.% to 8 wt.% of at least one β-hydroxy acid selected from the group consisting of salicylic acid, 5-n-octanoyl salicylic acid, 5-n-decanoyl salicylic acid, 5-n-dodecanoyl salicylic acid, 5-n-heptyl salicylic acid, 4-n-heptyl salicylic acid, and combinations thereof; b) 2 to 8 wt.% of at least one nonionic surfactant selected from the group consisting of decyl glucoside, lauryl glucoside, coco-glucoside, octyl glucoside, octyl / decyl glucoside, and combinations thereof; c) 0.4 wt.% to 0.8 wt.% of at least one cationic surfactant selected from the group consisting of oleamidopropyl dimethylamine, stearamidopropyl dimethylamine, isostearamidopropyl dimethylamine, stearamidoethyl dimethylamine, behenamidopropyl dimethylamine, palmitamidopropyl dimethylamine, rapeamidopropyl dimethylamine, stearamidoethyl diethylamine, and combinations thereof; d) water; and e) 12 to 18 wt.% of at least one anionic surfactant; The pH of the composition is between 3.5 and 4.5.

[0079] Preparation and use The composition according to the invention can be prepared by mixing components a) to d) as essential ingredients and additional ingredients (as explained above).

[0080] The method and tools for mixing the above essential ingredients and optional ingredients are not limited. Any conventional method and tools may be used to mix the above essential ingredients and optional ingredients to prepare the composition according to the present invention.

[0081] The composition according to the invention may have a gel-like texture.

[0082] According to a second aspect of the invention, a method for cleansing hair comprises applying to the hair a composition as described above and subsequently rinsing with water after any exposure period.

[0083] The following examples are given by way of illustration of the present invention and should not be construed as limiting the scope. Example The main raw materials used, their trade names and suppliers are listed in Table 1. Table 1

[0085] Inventive Examples 1-2 and Comparative Examples 1-4 Shampoos according to Inventive Examples (IE.) 1-2 and shampoos according to Comparative Examples (CE.) 1-4 were prepared using the ingredients listed in Table 2 (the contents are expressed as weight percentages of active material relative to the total weight of the respective shampoo unless otherwise indicated): Table 2 Element IE.1 IE.2 CE.1 CE.2 CE.3 CE.4 Sodium Laureth Sulfate 15 15 15 15 15 15 Decyl Glucoside 2.65 2.65 2.65 2.65 Cocamide MEA 2 Cocamide MIPA 1 Laureth-9 2.65 lactic acid 5.4 5.4 5.4 5.4 5.4 Salicylic acid 1.5 1.5 1.5 1.5 1.5 Rapeseed Amidopropyl Dimethylamine 0.50 0.50 0.50 0.5 0.5 Stearamidopropyl dimethylamine 0.50 Sodium hydroxide 1.27 1.27 1.31 1.27 1.27 0.1 water Appropriate amount up to 100 Appropriate amount up to 100 Appropriate amount up to 100 Appropriate amount up to 100 Appropriate amount up to 100 Appropriate amount up to 100 PH 4.3 3.8 3.8 3.8 3.8 4.0 The shampoo of Inventive Examples IE 1-2 is a composition according to the present invention.

[0086] The shampoo of Comparative Example CE 1 did not contain any fatty amidoamine.

[0087] The shampoo of Comparative Example CE2 contained different nonionic surfactants - cocamide MEA and cocamide MIPA.

[0088] The shampoo of Comparative Example CE3 contained a different nonionic surfactant, Laureth-9.

[0089] The shampoo of Comparative Example CE 4 contained no hydroxy acid.

[0090] Preparation Procedure: Taking the shampoo of Inventive Example 1 as an example, each shampoo was prepared as follows.

[0091] 1) Add rapeseed amidopropyl dimethylamine and stearamidopropyl dimethylamine to water under stirring, heat to 75° C. or higher, and mix until transparent; 2) adding lactic acid, salicylic acid and sodium hydroxide to the transparent base under stirring; 3) Add sodium laureth sulfate and decyl glucoside and mix until transparent; 4) Adjust pH to 4.3 with sodium hydroxide.

[0092] Evaluate: Cell viability Cell viability was determined on the D6 model by MTT assay.

[0093] D6 Model: EpiSkin was used in this study TM Reconstruct the epidermis model.

[0094] EpiSkin TM Tissues and culture medium were purchased from Shanghai Si'anfunuo Biotechnology Co., Ltd. EpiSkin used in this study TM The size of the tissue is 1.07cm 2 .

[0095] Testing Procedure: 1) 2.5% diluted shampoo (30 μl) was topically applied to the D6 epidermal model using a nylon mesh for 45 minutes at room temperature. The exposure was terminated by rinsing with phosphate buffered saline (PBS). Two epidermal units were used for each test group.

[0096] 2) Post-incubation: The epidermis was then incubated at 37°C for an additional 18 h; 3) The epidermis was incubated with MTT solution (3-(4,5-dimethylthiazolyl-2)-2,5-diphenyltetrazolium bromide) for 3 hours. The precipitated formazan was then extracted with acidified isopropanol at 4°C for 2 days and quantified spectrophotometrically at 570 nm using a 96-well plate.

[0097] 4) The optical density value was quantitatively measured by spectrophotometry at 570 nm using MULTISKAN ASCENT, and the cell viability (%) was then calculated via sample OD value / blank OD value.

[0098] Long-lasting scalp cleansing The cleansing effect of each shampoo was evaluated as follows: Six volunteers were recruited, and half of each volunteer's hair was washed with the shampoo to be tested, and the other half of each volunteer's hair was washed with the reference.

[0099] A silicone-free shampoo (Loreal Hyaluronic Acid Shampoo-WATER PUMP from Loreal) was used as a benchmark in the above cleaning evaluation.

[0100] The volunteers gave scores on the cleaning effect of each tested shampoo 24 hours after application, and the scores were averaged. The scores on the cleaning effect were given 24 hours after application.

[0101] The scoring criteria for the conditioning effect and cleansing effect of each tested shampoo are as follows.

[0102] --: The test shampoo is significantly inferior to the benchmark; -: the tested shampoo was slightly inferior to the benchmark; =: Test shampoo is similar to the benchmark; +: the tested shampoo was slightly better than the baseline; and ++: The tested shampoo was significantly better than the benchmark.

[0103] The results of cell viability and sustained scalp cleansing are summarized in Table 3. Table 3 nature IE.1 IE.2 CE.1 CE.2 CE.3 CE.4 Cell survival rate (%) 85 85.20 67 55 49 60 Long-lasting scalp cleansing + + + + + -

[0104] Cell viability is a measure of the proportion of live healthy cells within a population. Cell viability assays are used to determine the overall health of cells, the higher the cell viability, the milder the shampoo. Higher cell viability means less irritation and less damage to stratum corneum cells. It can be seen that the composition according to the present invention is better in terms of cell viability. That is, the composition according to the present invention shows a reduced irritation effect on the scalp. And at the same time, the composition according to the present invention can provide a sufficient and long-lasting cleaning effect.

Claims

1. A composition for cleaning hair, comprising: a) at least one hydroxy acid; b) at least one nonionic surfactant selected from alkyl (poly)glycosides; c) at least one cationic surfactant selected from fatty amidoamines and salts thereof corresponding to the following formula (I): RCONHR"N(R′)2 (I) wherein R is a linear or branched non-cyclic alkyl or alkenyl group containing 16 to 22 carbon atoms; R" is a divalent hydrocarbon radical containing less than 6 carbon atoms, and R, which may be the same or different, represents a hydrocarbon group containing less than 6 carbon atoms; and d) Solvent.

2. The composition according to claim 1, wherein the hydroxy acid is selected from the group consisting of alpha-hydroxy acids and beta-hydroxy acids, and combinations thereof.

3. The composition according to claim 2, wherein the α-hydroxy acid is selected from lactic acid, glycolic acid, tartaric acid, mandelic acid, citric acid, and combinations thereof, preferably, the α-hydroxy acid is lactic acid.

4. The composition according to any one of claims 2-3, wherein the α-hydroxy acid is present in an amount ranging from 0.1 wt.% to 30 wt.%, preferably from 0.5 wt.% to 20 wt.%, and more preferably from 1.5 wt.% to 10 wt.%, relative to the total weight of the composition.

5. The composition according to any one of claim 2, wherein the β-hydroxy acid is selected from salicylic acid and its derivatives of formula (II): wherein R is a linear, branched or cyclic saturated aliphatic group, or an aliphatic unsaturated group containing one or more double bonds which may or may not be conjugated, these groups contain 2 to 22, preferably 3 to 11 carbon atoms, and can be substituted by, for example, at least one substituent selected from the following: (a) a halogen atom, (b) a trifluoromethyl group, (c) a hydroxyl group in free form or esterified with an acid having 1 to 6 carbon atoms, or (d) a free carboxyl functional group or a carboxyl functional group esterified with a lower alcohol having 1 to 6 carbon atoms; R is a hydroxyl group or an ester functional group of the following formula (III): wherein R1 is a straight or branched saturated or unsaturated aliphatic group having 1 to 18 carbon atoms, Preferably, the β-hydroxy acid is selected from salicylic acid, 5-n-octanoyl salicylic acid, 5-n-decanoyl salicylic acid, 5-n-dodecanoyl salicylic acid, 5-n-heptyl salicylic acid, 4-n-heptyl salicylic acid, and combinations thereof. More preferably, the beta-hydroxy acid is salicylic acid.

6. The composition according to any one of claims 2-5, wherein the β-hydroxy acid is present in an amount ranging from 0.1 wt.% to 30 wt.%, preferably from 0.5 wt.% to 15 wt.%, and more preferably from 1 wt.% to 8 wt.%, relative to the total weight of the composition.

7. A composition according to any one of the preceding claims, comprising at least one alpha-hydroxy acid and at least one beta-hydroxy acid, preferably lactic acid and salicylic acid.

8. A composition according to any one of the preceding claims, wherein the at least one nonionic surfactant selected from alkyl (poly)glycosides comprises at least one compound selected from those of formula (IV): R1O-(R2O) t -(G)v (IV) in: R1 represents a straight chain or branched chain saturated or unsaturated hydrocarbon group containing about 8 to 24 carbon atoms, preferably 8 to 18 carbon atoms, or an alkylphenyl group in which the straight chain or branched chain alkyl group contains 8 to 24 carbon atoms; R2 represents an alkylene group containing about 2 to 4 carbon atoms; G represents a sugar unit containing 5 or 6 carbon atoms, preferably glucose, fructose or galactose; t is a number ranging from 0 to 10, preferably from 0 to 4, more preferably from 0 to 3; and v is a number ranging from 1 to 15.

9. The composition according to any one of the preceding claims, wherein the at least one nonionic surfactant selected from alkyl (poly)glycosides comprises at least one polyalkyl glycoside selected from the group consisting of decyl glucoside, lauryl glucoside, coco-glucoside, octyl glucoside, octyl / decyl glucoside, and combinations thereof.

10. A composition according to any of the preceding claims, wherein the total amount of the at least one nonionic surfactant ranges from about 0.1 wt.% to about 20 wt.%, preferably from about 1 wt.% to about 12 wt.%, more preferably from about 2 wt.% to about 8 wt.%, relative to the total weight of the composition.

11. The composition according to any of the preceding claims, wherein the cationic surfactant is selected from oleamidopropyl dimethylamine, stearamidopropyl dimethylamine, isostearamidopropyl dimethylamine, stearamidoethyl dimethylamine, behenamidopropyl dimethylamine, palmitamidopropyl dimethylamine, rapeamidopropyl dimethylamine, stearamidoethyl diethylamine, and combinations thereof.

12. A composition according to any one of the preceding claims, wherein the cationic surfactant is present in an amount ranging from 0.1 wt.% to 2 wt.%, preferably from 0.2 wt.% to 1.5 wt.%, more preferably from 0.4 wt.% to 0.8 wt.%, relative to the total weight of the composition.

13. The composition according to any one of the preceding claims, wherein the composition further comprises an anionic surfactant.

14. The composition according to claim 13, wherein the anionic surfactant is selected from: - C6-C24 and in particular C12-C20 alkyl sulfates; - C6-C24 and in particular C12-C20 alkyl ether sulfates; preferably containing 2 to 20 ethylene oxide units; - C6-C24 and in particular C12-C20 alkyl sulfosuccinates, in particular lauryl sulfosuccinate; - C6-C24 and in particular C12-C20 alkyl ether sulfosuccinates; - C6-C24 acyl isethionate, and preferably C12-C18 acyl isethionate; In particular, they are in the form of alkali metal salts, such as sodium salts, or alkaline earth metal salts, ammonium salts or amino alcohol salts.

15. The composition according to claim 13 or 14, wherein the anionic surfactant is present in an amount ranging from 5 wt.% to 50 wt.%, preferably from 9 wt.% to 25 wt.%, more preferably from 12 wt.% to 18 wt.%, relative to the total weight of the composition.

16. The composition according to any one of the preceding claims, wherein the solvent is selected from water, polyols including glycerol, hexylene glycol, glycol ethers, and combinations thereof, preferably water.

17. A composition according to any one of the preceding claims, wherein the composition has a pH of from 2 to 6.5, preferably from 3.5 to 4.

5.

18. A composition according to any one of the preceding claims, comprising, relative to the total weight of the composition: a) 1.5 wt.% to 10 wt.% of at least one lactic acid and 1 wt.% to 8 wt.% of at least one β-hydroxy acid selected from the group consisting of salicylic acid, 5-n-octanoyl salicylic acid, 5-n-decanoyl salicylic acid, 5-n-dodecanoyl salicylic acid, 5-n-heptyloxy salicylic acid, 4-n-heptyloxy salicylic acid, and combinations thereof; b) 2 to 8 wt.% of at least one nonionic surfactant selected from the group consisting of decyl glucoside, lauryl glucoside, coco-glucoside, octyl glucoside, octyl / decyl glucoside, and combinations thereof; c) 0.4 wt.% to 0.8 wt.% of at least one cationic surfactant selected from the group consisting of oleamidopropyl dimethylamine, stearamidopropyl dimethylamine, isostearamidopropyl dimethylamine, stearamidoethyl dimethylamine, behenamidopropyl dimethylamine, palmitamidopropyl dimethylamine, rapeamidopropyl dimethylamine, stearamidoethyl diethylamine, and combinations thereof; d) water; and e) 12 to 18 wt.% of at least one anionic surfactant; The pH of the composition is between 3.5 and 4.

5.

19. A method for cleansing hair comprising applying to the hair a composition according to any preceding claim and subsequently rinsing the hair with water after any exposure period.

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