Micromolecular compound fermentation keratin hair core repairing composition and application

Abstract

The invention relates to the technical field of daily chemicals, in particular to a micromolecular compound fermentation keratin hair core repairing composition and application. The composition comprises water, hydrolyzed rice protein, hydrolyzed wheat protein, hydrolyzed soybean protein, hydrolyzed keratin and hydrolyzed corn protein. The coco-dimethyl ammonium hydroxypropyl hydrolyzed wheat protein is matched, can penetrate into hair, and is combined with binary acid to form a cross-linking agent, so that the toughness of the hair is improved, and meanwhile, relatively good dry and wet combing property is given to the hair. Meanwhile, amino groups on the newly added high-molecular components and amino acids in the hydrolyzed soybean protein can form double charges of positive charges, so that the product is relatively stable.

Description

Technical Field

[0001] The invention relates to the technical field of daily chemicals, and in particular to a small molecule composite fermented keratin hair core repairing composition and application thereof. Background Art

[0002] Nowadays, virtually all shampoos can be used frequently and make hair more manageable. Hair consumers have the following main expectations for shampoos: clean hair well; do not make hair dry; do not make hair greasy; rinse easily; be mild; make hair soft; make hair shiny.

[0003] In general, respondents were dissatisfied with very few aspects of the products they use daily, mainly including: feeling that there is a covering on the hair; hair is not fluffy and full; hair gradually loses elasticity; conditioning is not enough; and the anti-dandruff effect is not ideal.

[0004] Hydrolyzed vegetable protein can provide a variety of amino acids, help form a uniform film on the surface of the hair, provide protection for the cuticle, and prevent the loss and degradation of protein from weakening and damaging the hair. Wheat is an ideal source of multiple vitamins and minerals.

[0005] In view of this, the present invention provides a small molecule composite fermented keratin hair core repairing composition and a preparation method and application thereof. Summary of the invention

[0006] In order to solve the above technical problems, the present invention provides a small molecule composite fermented keratin hair core repairing composition, which comprises: water, hydrolyzed rice protein, hydrolyzed wheat protein, hydrolyzed soy protein, hydrolyzed keratin, and hydrolyzed corn protein.

[0007] As an embodiment of the present invention, the composition comprises, in terms of mass percentage: water balance, hydrolyzed rice protein: 5%-8%, hydrolyzed wheat protein: 5%-8%, hydrolyzed soy protein: 5%-8%, hydrolyzed keratin: 0.1%-1%, and hydrolyzed corn protein: 0.05%-0.5%.

[0008] As an embodiment of the present invention, the composition further comprises: 1-5% of budding pullulan polysaccharide, 0.1%-0.5% of cocodimethylammonium hydroxypropyl hydrolyzed wheat protein, 1%-3% of butylene glycol, 0.3%-0.8% of phenoxyethanol, 0.3%-0.5% of sodium benzoate, 0.1%-0.5% of 1,2-hexanediol, and 0.1%-0.5% of p-hydroxyacetophenone.

[0009] The second aspect of the present invention provides a small molecule protein hair core repairing agent, comprising the small molecule composite fermented keratin hair core repairing composition.

[0010] As an embodiment of the present invention, the small molecule protein hair core repairing agent is prepared from raw materials comprising:

[0011] Carbomer

[0012] Deionized water

[0013] Fatty alcohol polyoxyethylene ether sodium sulfate

[0014] RSAW AL70 / ZA (Ammonium Lauryl Sulfate)

[0015] Sodium Lauryl Sulfate

[0016] Allantoin

[0017] UCARE Polymer JR-400 (Polyquaternium-10)

[0018] n-hance 3196 cationic guar (guar hydroxypropyltrimonium chloride)

[0019] Palm Kernel Oleamide DEA

[0020] TC-CAB 35B (cleaning agent)

[0021] S / SN 35 (complex amino acid surfactant)

[0022] A small molecule composite fermented keratin hair core repairing composition

[0023] CMgel OIL (glycerol mixture)

[0024] D-Panthenol

[0025] Phenoxyethanol

[0026] Sodium Benzoate

[0027] (Daily Use) Fragrance

[0028] Sodium chloride

[0029] Ethylhexylglycerin.

[0030] As an embodiment of the present invention, the composite amino acid surfactant comprises sodium lauroyl sarcosinate and sodium lauroyl glutamate in a mass ratio of 30:0.1.

[0031] As an embodiment of the present invention, the glycerol mixture comprises: glycerol, glycerol acrylate / acrylic acid copolymer, PVM / MA copolymer, propylene glycol, 1,2-hexanediol, and water; the mass ratio is: 39:1:0.3:1.5:0.7:57.5.

[0032] As an embodiment of the present invention, the cleaning agent comprises cocamidopropyl betaine and sebacic acid.

[0033] The third aspect of the present invention provides a small molecule protein hair core repairing agent, which is applied in the field of daily chemicals.

[0034] The fourth aspect of the present invention provides a method for preparing the small molecule protein hair core repairing agent, and the preparation method is as follows:

[0035] S01 Add carbomer and deionized water to the main pot, stir and disperse evenly, then add pre-dispersed palm kernel oil amide DEA, heat to 80-85℃, disperse evenly, and keep warm and stir for 20 minutes;

[0036] After S02 is kept warm, add ammonium lauryl sulfate, sodium dodecyl sulfate, and allantoin in sequence, return the temperature to 80°C, stir and disperse evenly. After confirming that there are no particles in the material, start cooling;

[0037] S03 At 60-65℃, add polyquaternium-10, guar hydroxypropyltrimonium chloride, detergent, composite amino acid surfactant and sodium chloride in sequence and stir to disperse evenly;

[0038] When S04 is below 45℃, add the remaining raw materials in sequence, stir and disperse evenly, then send for inspection and test, and discharge after passing the test.

[0039] By adopting the above technical solution, the present invention has the following beneficial effects:

[0040] After dyeing, some parts of the hair are damaged while others are not. Surfactants are more likely to take effect at the junction, causing more surface shedding. At this time, a shampoo with stronger cleaning power should be selected. At the same time, the more serious the damage, the more hydrophilic the hair is. As a result, the use of silicone oil skin care products in the later stage can only temporarily make the hair feel better. In fact, it cannot fundamentally solve the problem of hair repair.

[0041] To this end, the present invention selects hydrolyzed rice protein, hydrolyzed wheat protein, hydrolyzed soy protein, and hydrolyzed corn protein, which have a certain affinity for damaged hair, combine with keratin, play an anchoring role, fix the protein on the hair, and promote the deposition of other amino acids and cosmetic active substances.

[0042] However, the inventors found that the above-mentioned plant protein has a weak adsorption capacity for hair that only has hair scales; they also found that the use of hydrolyzed plant protein with a smaller molecular weight can accelerate the repair of hair; however, it was found that the use of this type of hydrolyzed plant protein is prone to stratification and dilution.

[0043] To this end, the present invention uses cocodimonium hydroxypropyl hydrolyzed wheat protein to penetrate into the hair and combine with dibasic acid to form a crosslinking agent, thereby increasing the toughness of the hair and giving the hair better dry and wet combing properties. At the same time, the amino groups on the newly added polymer components can form a positive double charge with the amino acids in the soy hydrolyzed protein, thereby making the product more stable. DETAILED DESCRIPTION

[0044] The technical solution of the present invention will be described clearly and completely below. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of them. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0045] The invention provides a small molecule composite fermented keratin hair core repairing composition. The composition comprises: water balance, hydrolyzed rice protein: 5%-8%, hydrolyzed wheat protein: 5%-8%, hydrolyzed soy protein: 5%-8%, hydrolyzed keratin: 0.1%-1%, hydrolyzed corn protein: 0.05%-0.5%, budding short pedunculate enzyme polysaccharide 1-5%, coconut oil dimethyl ammonium hydroxypropyl hydrolyzed wheat protein 0.1%-0.5%, butylene glycol: 1%-3%, phenoxyethanol: 0.3%-0.8%, sodium benzoate: 0.3%-0.5%, 1,2-hexanediol: 0.1%-0.5%, and p-hydroxyacetophenone: 0.1%-0.5%.

[0046] As a preferred embodiment of the present invention, the composition comprises: water balance, 6.5% hydrolyzed rice protein, 5.5% hydrolyzed wheat protein, 5.2% hydrolyzed soy protein, 0.6% hydrolyzed keratin, 0.2% hydrolyzed corn protein, 1.1% budding pullulan polysaccharide, 0.2% coconut oil dimethyl ammonium hydroxypropyl hydrolyzed wheat protein, 1.5% butylene glycol, 0.4% phenoxyethanol, 0.3% sodium benzoate, 0.2% 1,2-hexanediol, and 0.2% p-hydroxyacetophenone.

[0047] The preparation methods of hydrolyzed rice protein, hydrolyzed wheat protein, hydrolyzed soy protein and hydrolyzed corn protein are as follows:

[0048] (1) soaking rice, wheat, soybeans, and corn (including corn germ) in 2 times the volume of water overnight, respectively, and filtering to obtain respective filtrates and soaking solutions;

[0049] (2) grinding and crushing the filtered material, passing through a 60-mesh sieve, adding an equal volume of 75% ethanol, mixing, stirring, and passing through a 50-mesh sieve to obtain a crushed material and a filtrate;

[0050] (3) mixing the crushed material in step (2) and the soaking liquid in step (1), adding 6 wt % neutral protease and alkaline protease (mass ratio 1:1) for enzymatic hydrolysis, inactivating the enzyme at 80 degrees Celsius for 10 minutes, and centrifuging to obtain a centrifuge;

[0051] (4) the filtrate in step (2) and the centrifuge in step (3) are mixed, and then the filtrate is evaporated at 30 degrees Celsius to obtain a mass that is the same as the raw material (rice, wheat, soybean, corn), thereby obtaining the hydrolyzed rice protein, hydrolyzed wheat protein, hydrolyzed soybean protein and hydrolyzed corn protein.

[0052] The small molecule protein hair core repairing agent is prepared by raw materials comprising:

[0053] Carbomer 0.3 parts

[0054] 14 parts of fatty alcohol polyoxyethylene ether sodium sulfate

[0055] 2 parts of ammonium lauryl sulfate

[0056] 0.5 parts of sodium lauryl sulfate

[0057] Allantoin 0.15 parts

[0058] Polyquaternium-10 0.06 parts

[0059] Guar Hydroxypropyltrimonium Chloride 0.2 parts

[0060] Palm kernel oleamide DEA 1 part

[0061] 2 parts of cleaning agent (containing cocamidopropyl betaine and sebacic acid, mass ratio is 4:1)

[0062] 3 parts of composite amino acid surfactant (including sodium lauroyl sarcosinate and sodium lauroyl glutamate, mass ratio is 30:0.1)

[0063] 3 parts of a small molecule composite fermented keratin hair core repair composition

[0064] 0.5 parts of glycerol mixture (glycerol, glycerol acrylate / acrylic acid copolymer, PVM / MA copolymer, propylene glycol, 1,2-hexanediol, water; mass ratio: 39:1:0.3:1.5:0.7:57.5)

[0065] D-Panthenol 0.02 parts

[0066] Phenoxyethanol 0.6 parts

[0067] 0.45 parts of sodium benzoate

[0068] (Daily use) 0.5 parts of flavor

[0069] 0.5 parts of sodium chloride

[0070] Ethylhexylglycerin 0.05 parts

[0071] Deionized water was added to make up to 100 parts.

[0072] The present invention is further explained below in conjunction with specific implementation modes.

[0073] Example 1

[0074] The present embodiment provides a small molecule composite fermented keratin hair core repairing composition, comprising water balance, 6.5% hydrolyzed rice protein, 5.5% hydrolyzed wheat protein, 5.2% hydrolyzed soy protein, 0.6% hydrolyzed keratin, 0.2% hydrolyzed corn protein, 1.1% budding pullulanase polysaccharide, 0.2% coconut oil dimethyl ammonium hydroxypropyl hydrolyzed wheat protein, 1.5% butylene glycol, 0.4% phenoxyethanol, 0.3% sodium benzoate, 0.2% 1,2-hexanediol, and 0.2% p-hydroxyacetophenone.

[0075] The preparation methods of hydrolyzed rice protein, hydrolyzed wheat protein, hydrolyzed soy protein and hydrolyzed corn protein are as follows:

[0076] (1) soaking rice, wheat, soybeans, and corn (including corn germ) in 2 times the volume of water overnight, respectively, and filtering to obtain respective filtrates and soaking solutions;

[0077] (2) grinding and crushing the filtered material, passing through a 60-mesh sieve, adding an equal volume of 75% ethanol, mixing, stirring, and passing through a 50-mesh sieve to obtain a crushed material and a filtrate;

[0078] (3) mixing the crushed material in step (2) and the soaking liquid in step (1), adding 6 wt % neutral protease and alkaline protease (mass ratio 1:1) for enzymatic hydrolysis, inactivating the enzyme at 80 degrees Celsius for 10 minutes, and centrifuging to obtain a centrifuge;

[0079] (4) the filtrate in step (2) and the centrifuge in step (3) are mixed, and then the filtrate is evaporated at 30 degrees Celsius to obtain a mass that is the same as the raw material (rice, wheat, soybean, corn), thereby obtaining the hydrolyzed rice protein, hydrolyzed wheat protein, hydrolyzed soybean protein and hydrolyzed corn protein.

[0080] The small molecule protein hair core repairing agent is prepared by raw materials comprising:

[0081] Carbomer 0.3 parts

[0082] 14 parts of fatty alcohol polyoxyethylene ether sodium sulfate

[0083] 2 parts of ammonium lauryl sulfate

[0084] 0.5 parts of sodium lauryl sulfate

[0085] Allantoin 0.15 parts

[0086] Polyquaternium-10 0.06 parts

[0087] Guar Hydroxypropyltrimonium Chloride 0.2 parts

[0088] Palm kernel oleamide DEA 1 part

[0089] 2 parts of cleaning agent (containing cocamidopropyl betaine and sebacic acid, mass ratio is 4:1)

[0090] 3 parts of composite amino acid surfactant (including sodium lauroyl sarcosinate and sodium lauroyl glutamate, mass ratio is 30:0.1)

[0091] 3 parts of a small molecule composite fermented keratin hair core repair composition

[0092] 0.5 parts of glycerol mixture (glycerol, glycerol acrylate / acrylic acid copolymer, PVM / MA copolymer, propylene glycol, 1,2-hexanediol, water; mass ratio: 39:1:0.3:1.5:0.7:57.5)

[0093] D-Panthenol 0.02 parts

[0094] Phenoxyethanol 0.6 parts

[0095] 0.45 parts of sodium benzoate

[0096] (Daily use) 0.5 parts of flavor

[0097] 0.5 parts of sodium chloride

[0098] Ethylhexylglycerin 0.05 parts

[0099] Deionized water was added to make up to 100 parts.

[0100] Example 2

[0101] The difference from Example 1 is that this embodiment provides a small molecule composite fermented keratin hair core repairing composition, comprising water residue, 6.5% hydrolyzed rice protein, 5.5% hydrolyzed wheat protein, 5.2% hydrolyzed soy protein, 0.6% hydrolyzed keratin, 0.2% hydrolyzed corn protein, 0.2% coconut dimethyl ammonium hydroxypropyl hydrolyzed wheat protein, 1.5% butylene glycol, 0.4% phenoxyethanol, 0.3% sodium benzoate, 0.2% 1,2-hexanediol, and 0.2% parahydroxyacetophenone.

[0102] Example 3

[0103] The difference from Example 1 is that this example provides a small molecule composite fermented keratin hair core repairing composition, in which hydrolyzed rice protein, hydrolyzed wheat protein, hydrolyzed soy protein, hydrolyzed keratin, and hydrolyzed corn protein are all commercially available.

[0104] Example 4

[0105] The difference from Example 1 is that this embodiment provides a small molecule composite fermented keratin hair core repairing composition, comprising water residue, 6.5% hydrolyzed rice protein, 5.5% hydrolyzed wheat protein, 5.2% hydrolyzed soy protein, 0.6% hydrolyzed keratin, 0.2% hydrolyzed corn protein, 1.1% budding short stalk enzyme polysaccharide, 0.2% coconut oil dimethyl ammonium hydroxypropyl hydrolyzed wheat protein, 1.5% butylene glycol, 0.4% phenoxyethanol, 0.3% sodium benzoate, 0.2% 1,2-hexanediol, and 0.2% para-hydroxyacetophenone.

[0106] The preparation methods of hydrolyzed rice protein, hydrolyzed wheat protein, hydrolyzed soy protein and hydrolyzed corn protein are as follows:

[0107] (1) soaking rice, wheat, soybeans, and corn (including corn germ) in 2 times the volume of water overnight, respectively, and filtering to obtain respective filtrates and soaking solutions;

[0108] (2) grinding and crushing the filtered material, passing through a 60-mesh sieve, adding an equal volume of 75% ethanol, mixing, stirring, and passing through a 50-mesh sieve to obtain a crushed material and a filtrate;

[0109] (3) mixing the crushed material in step (2) and the soaking liquid in step (1), adding 6 wt % neutral protease and alkaline protease (mass ratio 1:1) for enzymatic hydrolysis, inactivating the enzyme at 80 degrees Celsius for 10 minutes, and centrifuging to obtain a centrifuge;

[0110] (4) the centrifuges in step (3) are mixed, and then the centrifuges are evaporated at 30 degrees Celsius to obtain a mass that is the same as the raw materials (rice, wheat, soybean, corn), thereby obtaining the hydrolyzed rice protein, hydrolyzed wheat protein, hydrolyzed soybean protein and hydrolyzed corn protein.

[0111] Example 5

[0112] The difference from Example 1 is that this embodiment provides a small molecule composite fermented keratin hair core repairing composition, comprising water residue, 6.5% hydrolyzed rice protein, 5.5% hydrolyzed wheat protein, 5.2% hydrolyzed soy protein, 0.6% hydrolyzed keratin, 0.2% hydrolyzed corn protein, 1.1% budding short stalk enzyme polysaccharide, 0.2% coconut oil dimethyl ammonium hydroxypropyl hydrolyzed wheat protein, 1.5% butylene glycol, 0.4% phenoxyethanol, 0.3% sodium benzoate, 0.2% 1,2-hexanediol, and 0.2% para-hydroxyacetophenone.

[0113] The preparation methods of hydrolyzed rice protein, hydrolyzed wheat protein, hydrolyzed soy protein and hydrolyzed corn protein are as follows:

[0114] (1) soaking rice, wheat, soybeans, and corn (including corn germ) in 2 times the volume of water overnight, respectively, and filtering to obtain respective filtrates and soaking solutions;

[0115] (2) grinding and crushing the filtered material, passing through a 60-mesh sieve, adding an equal volume of 75% ethanol, mixing, stirring, and passing through a 50-mesh sieve to obtain a crushed material and a filtrate;

[0116] (3) mixing the crushed material in step (2) and the soaking liquid in step (1), adding 6 wt % neutral protease and alkaline protease (mass ratio 1:1) for enzymatic hydrolysis, inactivating the enzyme at 80 degrees Celsius for 10 minutes, and centrifuging to obtain a centrifuge;

[0117] (4) the filtrate in step (2) and the centrifuge in step (3) are mixed, and then the filtrate is evaporated at 30 degrees Celsius to obtain a mass that is the same as the raw material (rice, wheat, soybean, corn), thereby obtaining the hydrolyzed rice protein, hydrolyzed wheat protein, hydrolyzed soybean protein and hydrolyzed corn protein.

[0118] The small molecule protein hair core repairing agent is prepared by raw materials comprising:

[0119] Carbomer 0.3 parts

[0120] 14 parts of fatty alcohol polyoxyethylene ether sodium sulfate

[0121] 2 parts of ammonium lauryl sulfate

[0122] 0.5 parts of sodium lauryl sulfate

[0123] Allantoin 0.15 parts

[0124] Polyquaternium-10 0.26 parts

[0125] Palm kernel oleamide DEA 1 part

[0126] 2 parts of cleaning agent (including cocamidopropyl betaine)

[0127] 3 parts of composite amino acid surfactant (including sodium lauroyl sarcosinate and sodium lauroyl glutamate, mass ratio is 30:0.1)

[0128] 3 parts of a small molecule composite fermented keratin hair core repair composition

[0129] 0.5 parts of glycerol mixture (glycerol, glycerol acrylate / acrylic acid copolymer, PVM / MA copolymer, propylene glycol, 1,2-hexanediol, water; mass ratio: 39:1:0.3:1.5:0.7:57.5)

[0130] D-Panthenol 0.02 parts

[0131] Phenoxyethanol 0.6 parts

[0132] 0.45 parts of sodium benzoate

[0133] (Daily use) 0.5 parts of flavor

[0134] 0.5 parts of sodium chloride

[0135] Ethylhexylglycerin 0.05 parts

[0136] Deionized water was added to make up to 100 parts.

[0137] Example 6

[0138] The present embodiment provides a small molecule composite fermented keratin hair core repairing composition, comprising water balance, 6.5% hydrolyzed rice protein, 5.5% hydrolyzed wheat protein, 5.2% hydrolyzed soy protein, 0.6% hydrolyzed keratin, 0.2% hydrolyzed corn protein, 1.1% budding pullulanase polysaccharide, 0.2% coconut oil dimethyl ammonium hydroxypropyl hydrolyzed wheat protein, 1.5% butylene glycol, 0.4% phenoxyethanol, 0.3% sodium benzoate, 0.2% 1,2-hexanediol, and 0.2% p-hydroxyacetophenone.

[0139] The preparation methods of hydrolyzed rice protein, hydrolyzed wheat protein, hydrolyzed soy protein and hydrolyzed corn protein are as follows:

[0140] (1) soaking rice, wheat, soybeans, and corn (including corn germ) in 2 times the volume of water overnight, respectively, and filtering to obtain respective filtrates and soaking solutions;

[0141] (2) grinding and crushing the filtered material, passing through a 60-mesh sieve, adding an equal volume of 75% ethanol, mixing, stirring, and passing through a 50-mesh sieve to obtain a crushed material and a filtrate;

[0142] (3) mixing the crushed material in step (2) and the soaking liquid in step (1), adding 6 wt % neutral protease and alkaline protease (mass ratio 1:1) for enzymatic hydrolysis, inactivating the enzyme at 80 degrees Celsius for 10 minutes, and centrifuging to obtain a centrifuge;

[0143] (4) the filtrate in step (2) and the centrifuge in step (3) are mixed, and then the filtrate is evaporated at 30 degrees Celsius to obtain a mass that is the same as the raw material (rice, wheat, soybean, corn), thereby obtaining the hydrolyzed rice protein, hydrolyzed wheat protein, hydrolyzed soybean protein and hydrolyzed corn protein.

[0144] The small molecule protein hair core repairing agent is prepared by raw materials comprising:

[0145] Carbomer 0.3 parts

[0146] 14 parts of fatty alcohol polyoxyethylene ether sodium sulfate

[0147] 2 parts of ammonium lauryl sulfate

[0148] 0.5 parts of sodium lauryl sulfate

[0149] Allantoin 0.15 parts

[0150] Guar Hydroxypropyltrimonium Chloride 0.26 parts

[0151] Palm kernel oleamide DEA 1 part

[0152] 2 parts of cleaning agent (containing cocamidopropyl betaine and sebacic acid, mass ratio is 4:1)

[0153] 3 parts of composite amino acid surfactant (including sodium lauroyl sarcosinate and sodium lauroyl glutamate, mass ratio is 30:0.1)

[0154] 3 parts of a small molecule composite fermented keratin hair core repair composition

[0155] 0.5 parts of glycerol mixture (glycerol, PVM / MA copolymer, propylene glycol, 1,2-hexanediol, water; mass ratio: 40:0.3:1.5:0.7:57.5)

[0156] D-Panthenol 0.02 parts

[0157] Phenoxyethanol 0.6 parts

[0158] 0.45 parts of sodium benzoate

[0159] (Daily use) 0.5 parts of flavor

[0160] 0.5 parts of sodium chloride

[0161] Ethylhexylglycerin 0.05 parts

[0162] Deionized water was added to make up to 100 parts.

[0163] Performance Testing

[0164] Test 1: Test of the nourishing effect of hair products. This method uses equipment to measure the improvement of glossiness and combing properties of hair pieces before and after using the sample to reflect the nourishing effect of the product on the hair.

[0165] Reagents and consumables: cleaning solution; in vitro human hair bundle (length ≥10cm, net weight ≥6g).

[0166] Test substance: Sample group: Examples 1-6.

[0167] Test method:

[0168] (1) Baseline dry hair test: The hair bundle to be tested is fully moistened with running constant temperature clean water, treated with cleaning solution, and placed in a constant temperature and humidity chamber (20-25°C, 40%-60%) for more than 4 hours. The hair bundle is then taken out and fixed in the test position for combing cycle test and gloss test.

[0169] (2) Dry hair sample test: The hair to be tested is fully moistened with running constant temperature clean water, and the sample is evenly applied on the surface of the hair at a rate of 0.2 g per gram of hair for about 30 seconds. The hair is left to stand for about 3-5 minutes. After rinsing, the hair is placed in a constant temperature and humidity chamber (20-25°C, 40%-60%) for more than 4 hours. The hair is then taken out and fixed in the test position for combing cycle test and gloss test.

[0170] (3) Record the combing work value and glossiness value of the test hair bundle before and after using the sample and perform data processing.

[0171] Combing power change rate = (A s -A0) / A0*100%.

[0172] Where: A0--combing work of baseline test;

[0173] A S --Combing work of the post-sampling treatment test.

[0174] Glossiness change rate = (C s -C0) / C0*100%.

[0175] Where: C0--gloss of baseline test;

[0176] C S --Glossiness of the sample after treatment test.

[0177] Table 1 Test results

[0178] Combing power change rate / % Gloss test results % Example 1 -26.573 13.622 Example 2 -20.123 10.238 Example 3 -18.245 7.983 Example 4 -19.293 9.385 Example 5 -23.291 12.126 Example 6 -23.464 12.315

[0179] Performance test 2: Anti-hair breakage efficacy test

[0180] The strength of hair is determined by its tensile properties. Hair that is difficult to stretch or break is relatively strong. It is usually expressed in terms of parameters such as tensile force (load), stress, elongation, and total work done at the breaking point, yield point, or specified point. This method is to uniformly stretch a single hair of equal length on a CTX texture analyzer until the hair breaks, and calculate the tensile strength and work done at break based on the curve. Since ambient temperature and humidity affect the tensile properties of hair, temperature and humidity control measures are required during the test to ensure that the temperature and humidity of the test environment are stable during and during the test.

[0181] Reagents and consumables: cleaning solution (sodium dodecyl sulfate solution); in vitro human hair bundle (length ≥15cm, net weight ≥6g).

[0182] Sample group: Test Examples 1 to 6.

[0183] Test method:

[0184] (1) Test before using the sample: The hair strand to be tested is fully moistened with running constant temperature clean water, and after being treated with the cleaning solution, it is placed in a constant temperature and humidity chamber [(26±2)℃, (60±10)%RH] to dry naturally for 24 hours, and a single-strand tensile test is performed, and the test data of each time is recorded.

[0185] (2) Test after using the sample: Rinse the hair bundle to be tested with running constant temperature clean water or do not rinse it according to the sample usage instructions. Apply 0.2g of sample per gram of hair bundle or the amount in accordance with the sample usage instructions evenly on the surface of the hair. After leaving it for a period of time, rinse it and use a soft and clean tissue to wipe the moisture on the surface of the hair or do not rinse it. Put the isolated hair into a constant temperature and humidity chamber [(26±2)℃, (60±10)%RH] to dry it naturally for 24 hours, and then perform a single-strand tensile test, and record the test data for each time.

[0186] Tensile strength change rate = (C s -C0) / C0*100%.

[0187] In the formula: C0---tensile strength of the sample before use;

[0188] C s ---Tensile strength of the sample after use.

[0189] Table 2 Tensile strength test results

[0190] Tensile strength change rate / % Example 1 22.005 Example 2 19.382 Example 3 18.032 Example 4 18.876 Example 5 21.352 Example 6 21.294

[0191] Performance Test 3: Mild Efficacy Test

[0192] The chicken embryo chorioallantoic membrane test is an early in vitro eye irritation assessment method. The chorioallantoic membrane (CAM) is a respiratory membrane that surrounds the chicken embryo. This test uses the characteristics of the intact, clear and transparent vascular system of the chorioallantoic membrane of the mid-stage incubated chicken embryo. A certain amount of the test substance is directly exposed to the chicken embryo chorioallantoic membrane. After a period of action, the changes in the toxic effect indicators of the chorioallantoic membrane (such as bleeding, coagulation and vascular melting) are observed. These indicators reflect the changes in the morphological structure, color and permeability of the blood vessels and vascular networks, as well as the phenomena such as the denaturation of the chorioallantoic membrane proteins and the degree of damage. Then, a score is obtained by combining them to evaluate the eye irritation of the test substance.

[0193] Reagents and consumables: 0.9% saline; 0.1 mol / L sodium hydroxide solution.

[0194] Sample: Sample diluted into 1% aqueous solution; Negative control: 0.9% saline; Positive control group: 0.1 mol / L sodium hydroxide solution.

[0195] Test method:

[0196] Select SPF fertilized chicken embryos, and when the chicken embryos are 9 days old, discard the unfertilized and inactive chicken embryos by egg candling. Select chicken embryos with well-developed blood vessels, and mark the position of the air chamber on the eggshell surface.

[0197] Carefully remove the eggshell and eggshell membrane with tweezers to ensure that the exposed allantoic membrane is intact and free of any damage. Apply the test substance to the CAM. After the action time is over, observe the degree of change of each toxic effect under a stereo microscope and give a score (ES).

[0198] ES = the sum of the extent of bleeding, coagulation, and vascular melting observed in 6 chick embryos / 3.

[0199] Data analysis: After taking the photo, score the bleeding, vascular melting and coagulation of the chicken embryo and calculate the ES value. Determine the irritation classification according to Table 3.

[0200] Table 3 Irritation classification

[0201] End point scoring Irritation classification ES≤4 Non-irritating 4<ES≤12 Mild irritation 12<ES<16 Moderate irritation ES≥16 Strong irritant / corrosive

[0202] Table 4 ES and irritation classification

[0203] End point scoring Irritation classification Negative control group Non-irritating Positive control group Mild irritation Example 1 Non-irritating Example 2 Non-irritating Example 3 Non-irritating Example 4 Non-irritating Example 5 Non-irritating Example 6 Non-irritating

[0204] Performance Test 4: Stability Test

[0205] The repairing agents prepared in Examples 1 to 6 were placed at 0°C and 45°C for 90 days to check their properties, and then placed alternately at 0°C and 45°C for 12 hours. This was repeated 6 times to check the product properties.

[0206] Example 1 0℃ 45℃ Hot and cold cycle Example 1 Viscous liquid Viscous liquid Viscous liquid Example 2 Viscous liquid Thinning Thinning Example 3 Viscous liquid Viscous liquid Viscous liquid Example 4 Viscous liquid Viscous liquid Viscous liquid Example 5 Thinning Thinning Thinning Example 6 Thinning Thinning Thinning

[0207] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit it. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the aforementioned embodiments, or replace some or all of the technical features therein with equivalents. However, these modifications or replacements do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of the present invention.

Claims

1. A small molecule composite fermented keratin hair core repairing composition, characterized in that: The composition comprises: water, hydrolyzed rice protein, hydrolyzed wheat protein, hydrolyzed soybean protein, hydrolyzed keratin and hydrolyzed corn protein.

2. A small molecule composite fermented keratin hair core repairing composition according to claim 1, characterized in that: Calculated by mass percentage, the composition comprises: water balance, hydrolyzed rice protein: 5%-8%, hydrolyzed wheat protein: 5%-8%, hydrolyzed soy protein: 5%-8%, hydrolyzed keratin: 0.1%-1%, and hydrolyzed corn protein: 0.05%-0.5%.

3. A small molecule composite fermented keratin hair core repairing composition according to claim 1, characterized in that: The composition further comprises: 1-5% of budding pullulan polysaccharide, 0.1%-0.5% of cocodimethylammonium hydroxypropyl hydrolyzed wheat protein, 1%-3% of butylene glycol, 0.3%-0.8% of phenoxyethanol, 0.3%-0.5% of sodium benzoate, 0.1%-0.5% of 1,2-hexanediol, and 0.1%-0.5% of p-hydroxyacetophenone.

4. A small molecule protein hair core repair agent, characterized in that: A small molecule composite fermented keratin hair core repairing composition comprising any one of claims 1 to 3.

5. A small molecule protein hair core repair agent according to claim 4, characterized in that: The raw materials for its preparation include: Carbomer Deionized water Fatty alcohol polyoxyethylene ether sodium sulfate Ammonium Lauryl Sulfate Sodium Lauryl Sulfate Allantoin Polyquaternium-10 Guar Hydroxypropyltrimonium Chloride Palm Kernel Oleamide DEA Cleaning agent Complex amino acid surfactant A small molecule composite fermented keratin hair core repairing composition Glycerin mixture D-Panthenol Phenoxyethanol Sodium Benzoate (Daily Use) Fragrance Sodium chloride Ethylhexylglycerin.

6. A small molecule protein hair core repair agent according to claim 5, characterized in that: The composite amino acid surfactant comprises sodium lauroyl sarcosinate and sodium lauroyl glutamate in a mass ratio of 30:0.

1.

7. A small molecule protein hair core repair agent according to claim 5, characterized in that: The glycerol mixture comprises: glycerol, glycerol acrylate / acrylic acid copolymer, PVM / MA copolymer, propylene glycol, 1,2-hexanediol, and water; the mass ratio is: 39:1:0.3:1.5:0.7:57.

5.

8. A small molecule protein hair core repair agent according to claim 5, characterized in that: The cleanser contains cocamidopropyl betaine and sebacic acid.

9. A small molecule protein hair core repair agent according to any one of claims 4 to 8, characterized in that: Used in daily chemical field.

10. A method for preparing a small molecule protein hair core repair agent according to any one of claims 4 to 8, characterized in that: The preparation method is as follows: S01 Add carbomer and deionized water to the main pot, stir and disperse evenly, then add pre-dispersed palm kernel oil amide DEA, heat to 80-85℃, disperse evenly, and keep warm and stir for 20 minutes; After S02 is kept warm, add ammonium lauryl sulfate, sodium dodecyl sulfate, and allantoin in sequence, return the temperature to 80°C, stir and disperse evenly. After confirming that there are no particles in the material, start cooling; S03 At 60-65℃, add polyquaternium-10, guar hydroxypropyltrimonium chloride, detergent, composite amino acid surfactant and sodium chloride in sequence and stir to disperse evenly; When S04 is below 45℃, add the remaining raw materials in sequence, stir and disperse evenly, then send for inspection and test, and discharge after passing the test.