Granulation equipment for carbamazepine compressed solid tablets

Abstract

The invention discloses carbamazepine compressed solid tablet granulation equipment, and particularly relates to the technical field of granulation, the carbamazepine compressed solid tablet granulation equipment mainly comprises a granulation box, an electric cylinder and a linkage block, the electric cylinder is fixed in front of the granulation box, the linkage block is fixed on the output end of the electric cylinder, and the bottom end of the linkage block is provided with a linkage adjusting mechanism; the linkage adjusting mechanism comprises a linkage strip fixedly installed at the bottom end of the linkage block, two connecting blocks are welded to the bottom end of the linkage strip, and the bottom end of each connecting block is fixedly connected with a shaft ring. The linkage adjusting mechanism and the electric cylinder push the linkage block to move, the linkage block drives the linkage strip to move and move forwards, the two connecting blocks can drive the two shaft rings to move forwards synchronously, the two linkage barrels can achieve sliding adjusting operation synchronously, the thickness of the granulation holes is adjusted according to needs, and the granulation efficiency is improved. And aiming at carbamazepine compressed solid tablet particles with different thicknesses, the granulating operation is realized, and the granulating applicability is wider.

Description

Technical Field

[0001] The present invention relates to the technical field of granulation, and more particularly to a granulation device for carbamazepine compressed solid tablets. Background Art

[0002] The carbamazepine compressed solid tablet granulation equipment generates extrusion force in the roller pressing die through roller pressing granulation, which can make the carbamazepine raw material powder more tightly combined together to form a stable tablet particle state, thereby improving the stability of the drug during storage and transportation.

[0003] After searching the existing published technical documents, the Chinese patent announcement number CN111111557A discloses a double-roll granulator, which squeezes the undemolded material on the outer surface of the active roller by fitting the outer surface of the second auxiliary roller with the outer surface of the active roller. The support frame is also provided with a guide structure, and the support frame and each auxiliary roller are connected with an elastic mechanism. The material that is not completely demolded can be transported to the space between the active roller and the corresponding auxiliary roller for secondary extrusion as the corresponding active roller rotates, and finally demolding and granulation are achieved. The granulator also has the following problems when used for roller pressing.

[0004] When the granulator granulates the carbamazepine compressed solid tablets, the carbamazepine powder raw material needs to be extruded into the designated die particle holes by extrusion force. However, during the extrusion process, since the carbamazepine compressed solid tablet particles need to be prepared in different thickness models according to requirements, it is difficult to accurately adjust the thickness of the granulation holes as required, and it is difficult to realize the granulation operation for carbamazepine compressed solid tablet particles of different thicknesses. The granulation applicability is poor. Therefore, it is necessary to provide carbamazepine compressed solid tablet granulation equipment. Summary of the invention

[0005] In order to overcome the above-mentioned defects of the prior art, the present invention provides a granulation device for compressed solid tablets of carbamazepine.

[0006] To achieve the above-mentioned purpose, the present invention provides the following technical solutions: a granulation device for compressed solid tablets of carbamazepine, comprising a granulation box, an electric cylinder and a linkage block, wherein the electric cylinder is fixed in front of the granulation box, the linkage block is fixed on the output end of the electric cylinder, and a linkage adjustment mechanism is installed at the bottom end of the linkage block; the linkage adjustment mechanism comprises a linkage bar fixedly installed at the bottom end of the linkage block, and two connecting blocks are welded at the bottom end of the linkage bar, and the bottom end of each connecting block is fixedly connected with an axle ring; the inner wall of the axle ring is rotatably connected with a grooved cylinder, and a linkage cylinder is welded at one end of the grooved cylinder, and a rotating shaft is slidably connected to the inner wall of the linkage cylinder, and a turntable is fixedly connected to one end of the rotating shaft, and a granulation roller is fixedly connected to the outer wall of the turntable, and the outer walls of the two granulation rollers are rotatably connected to the granulation box; the outer wall of the linkage cylinder is provided with a hole thickness adjustment mechanism; a positioning adjustment mechanism is installed at one end of the turntable.

[0007] Preferably, the two granulating rollers are rotatably connected, and the vertical cross-section of the granulating roller is set to a circular ring shape, the top of the granulating box is fixedly connected with a feed hopper, and the feed hopper is communicated with the granulating box; the inner wall of the feed hopper of the granulating box is set to a smooth surface, a controller is fixedly installed on one side of the granulating box, a support frame is fixedly connected to the outer wall of the granulating box and located below the controller, guide plates are fixedly connected on both sides of the inner wall of the granulating box, the guide plates are rotatably connected to the outer walls of the granulating rollers, a convex strip is welded on the top of the outer wall of the rotating shaft, and the convex strip is slidably connected to the inner wall of the linkage cylinder.

[0008] During the granulation operation, the electric cylinder pushes the linkage block to move, and the linkage block drives the linkage bar to move and move the linkage bar forward. The two connecting blocks can respectively drive the two shaft rings to move forward synchronously, so that the shaft rings can carry the grooved drum forward, and the linkage drum can slide forward along the outer wall of the rotating shaft and the outer wall of the convex strip. The turntable can support the rotating shaft, so that the two linkage drums can realize the sliding operation synchronously.

[0009] Preferably, the hole thickness adjustment mechanism comprises a plurality of guide frames fixedly arranged on the outer wall of the linkage cylinder; the top and bottom ends of the guide frames are slidably connected with slip rings, the inner wall of the guide frame is slidably connected with a sliding shaft, and the inner walls of the two slip rings are welded to the outer wall of the sliding shaft; A slider is welded to the bottom end of the sliding shaft, and an adjustment strip is fixedly installed on one side of the slider, and a plurality of adjustment columns are fixedly connected to one side of the adjustment strip, and the plurality of adjustment columns are equidistantly arranged in sequence from front to back; a plurality of granulation holes are opened on the outer wall of the granulation roller, and the adjustment columns are slidably connected to the granulation roller to which the granulation holes belong, the two slip rings are symmetrically arranged about the guide frame, and the plurality of adjustment strips are equidistantly arranged in a circular ring.

[0010] In the present technical solution, when the granulation operation is performed, the linkage cylinder drives multiple guide frames to move forward, the guide frame drives the sliding shaft to move forward and away from the center point of the linkage cylinder, the sliding shaft drives the two slip rings to slide along the guide frame, the sliding shaft drives the slider to move away from the center point of the linkage cylinder, the slider drives the adjustment bar to move away from the center point of the linkage cylinder, and the adjustment column moves away from the center point of the linkage cylinder inside the granulation hole, so that the adjustment column adjusts the thickness of the granulation hole. When the adjustment bar moves away from the center point of the linkage cylinder, the adjustment bar will drive the linkage plate to move away from the center point of the linkage cylinder, and the distance sensing block can move toward the distance sensor. When the value sensed by the distance sensor and the value sensed by another distance sensor are superimposed, they can be the same as the granulation adjustment thickness value set by the controller, then the electric cylinder is closed by the controller.

[0011] Preferably, the positioning adjustment mechanism comprises a sensing rod fixedly mounted on one end of the turntable; The outer wall of the sensor rod is rotatably connected to the granulation box, and one end of the sensor rod is coaxially connected to a stepper motor, a support block is installed at the bottom end of the stepper motor, and the granulation box and the stepper motor are fixedly connected to the support block; a pillar fixedly connected to the granulation box is provided below the collar, a support plate is welded to one end of the pillar, and two distance sensors are fixedly installed on the inner wall of the support plate; two sleeve blocks are welded to one side of the support plate, and a proximity sensor is fixedly installed on the inner wall of the sleeve block. A linkage plate is welded to one end of the adjustment bar, a distance sensing block is fixedly connected to one end of the linkage plate, and a positioning sensing block is fixedly installed on one side of the distance sensing block; the positioning sensing block is fixedly connected to the linkage plate, and the right side surface of the distance sensing block and the right end surface of the adjustment column are in the same vertical plane.

[0012] When the granulation operation is performed in this technical solution, the controller starts two stepper motors, and two sensor rods rotate inside the granulation box. The turntable carries the granulation roller to rotate, and the granulation roller carries multiple adjustment columns to rotate, and the adjustment columns drive the adjustment bars to rotate, and the linkage plate drives the distance sensing block to rotate downward. At the same time, the distance sensing block drives the positioning sensing block to rotate downward. When the positioning sensing block is located at the sensing part of the proximity sensor, the two stepper motors are turned off by the controller, and at the same time, the distance sensing block is located above the distance sensor and parallel to it, and the other distance sensing block is located above the other distance sensor and parallel to it. The distance sensing block is accurately moved to the position above the distance sensor.

[0013] Technical effects and advantages of the present invention: The present invention uses a linkage adjustment mechanism, an electric cylinder drives the linkage block to move, the linkage block drives the linkage bar to move, and the linkage bar moves forward, the two connecting blocks can respectively drive the two shaft rings to move forward synchronously, and the linkage cylinder slides forward along the outer wall of the rotating shaft and the outer wall of the convex strip, so that the two linkage cylinders can synchronously realize the sliding adjustment operation, the thickness of the granulation hole can be adjusted as needed, and the granulation operation can be realized for carbamazepine compressed solid tablet particles of different thicknesses, and the granulation applicability is wider.

[0014] The present invention utilizes a hole thickness adjustment mechanism. When a linkage cylinder drives a plurality of guide frames to move forward, the guide frames drive the sliding shafts to move forward and away from the center point of the linkage cylinder. Two slip rings slide along the guide frames. The sliding shafts drive the sliders to move away from the center point of the linkage cylinder. The adjustment bar moves away from the center point of the linkage cylinder. The adjustment column moves away from the center point of the linkage cylinder inside the granulation hole. The adjustment column adjusts the thickness of the granulation hole, and synchronously adjusts the granulation thickness inside the plurality of granulation holes.

[0015] The present invention adopts a positioning adjustment mechanism, a controller starts two stepper motors, the two stepper motors respectively drive two sensing rods, the sensing rods drive a turntable to rotate, the turntable carries a granulating roller to rotate, the adjustment column drives an adjustment bar to rotate, and a linkage plate drives a distance sensing block to rotate downward. When the positioning sensing block is located at a sensing position of a proximity sensor, the two stepper motors are closed by the controller, the distance sensing block is located above the distance sensor and parallel to it, and another distance sensing block is located above another distance sensor and parallel to it. When the value sensed by the distance sensor and the value sensed by the other distance sensor are superimposed and can be the same as the granulating adjustment thickness value set by the controller, the electric cylinder is closed by the controller, and the granulating thickness of multiple granulating holes can be accurately adjusted.

[0016] According to the mutual influence of multiple functions, when the positioning sensing block is located at the sensing part of the proximity sensor, the two stepping motors are turned off by the controller, and then the two linkage cylinders are synchronously adjusted to realize the sliding adjustment operation, and finally the adjustment column moves away from the center point of the linkage cylinder inside the granulation hole until the value sensed by the distance sensor and the value sensed by another distance sensor are superimposed to be the same as the granulation adjustment thickness value set by the controller. In summary, the thickness of the granulation hole can be adjusted as needed, and the carbamazepine compressed solid tablet particles of different thicknesses can be used to realize precise granulation operation, and the granulation applicability is wider. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] Figure 1 It is a schematic diagram of the main structure of the carbamazepine compressed solid tablet granulation equipment of the present invention.

[0018] Figure 2 It is a schematic diagram of the partial structure of the connection between the granulating box and the electric cylinder of the present invention.

[0019] Figure 3 It is a schematic diagram of the cross-sectional structure of the carbamazepine compressed solid tablet granulation equipment of the present invention.

[0020] Figure 4 It is a schematic diagram of the top view of the structure of the carbamazepine compressed solid tablet granulation equipment of the present invention.

[0021] Figure 5 For the present invention Figure 3 A in the figure is a schematic diagram of the enlarged structure.

[0022] Figure 6 It is a schematic diagram of the partial structure of the hole thickness adjustment mechanism of the present invention from a front view.

[0023] Figure 7 It is a schematic diagram of the partial structure of the cross section of the connection between the rotating disk and the rotating shaft of the present invention.

[0024] Figure 8 It is a schematic diagram of the partial structure of the connection between the support and the granulation box of the present invention.

[0025] Fig. 9 It is a schematic diagram of the local structure of the connection between the distance sensor and the support plate of the present invention from a top view.

[0026] Fig.10 It is a schematic diagram of the partial structure of the cross section of the connection between the adjustment strip and the linkage plate of the present invention.

[0027] The accompanying drawings are marked as follows: 1. granulation box; 2. electric cylinder; 3. linkage block; 4. linkage strip; 5. connection block; 6. shaft ring; 7. grooved cylinder; 8. linkage cylinder; 9. rotating shaft; 10. turntable; 11. granulation roller; 12. feed hopper; 13. controller; 14. support frame; 15. guide plate; 16. convex strip; 17. guide frame; 18. slip ring; 19. sliding shaft; 20. slider; 21. adjustment strip; 22. adjustment column; 23. granulation hole; 24. sensor rod; 25. stepping motor; 26. support block; 27. pillar; 28. support plate; 29. ​​distance sensor; 30. sleeve block; 31. proximity sensor; 32. linkage plate; 33. distance sensing block; 34. positioning sensing block. DETAILED DESCRIPTION

[0028] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0029] As attached Figure 1-10The carbamazepine compressed solid tablet granulation equipment shown in the figure is provided with a linkage adjustment mechanism, a hole thickness adjustment mechanism, and a positioning adjustment mechanism. The settings of each mechanism can adjust the thickness of the granulation hole 23 as needed, and can achieve precise granulation operation for carbamazepine compressed solid tablet particles of different thicknesses, and the granulation applicability is wider. The specific structural settings of each mechanism are as follows.

[0030] In this embodiment, as shown in the attached Figure 1-5 As shown, the electric cylinder 2 is fixed in front of the granulation box 1, the linkage block 3 is fixed on the output end of the electric cylinder 2, and a linkage adjustment mechanism is installed at the bottom end of the linkage block 3; the linkage adjustment mechanism includes a linkage bar 4 fixedly installed at the bottom end of the linkage block 3, and two connecting blocks 5 are welded to the bottom end of the linkage bar 4, and the bottom end of each connecting block 5 is fixedly connected with a shaft ring 6; the inner wall of the shaft ring 6 is rotatably connected with a grooved cylinder 7, and a linkage cylinder 8 is welded at one end of the grooved cylinder 7, and a rotating shaft 9 is slidably connected to the inner wall of the linkage cylinder 8, and a turntable 10 is fixedly connected to one end of the rotating shaft 9, and a granulating roller 11 is fixedly connected to the outer wall of the turntable 10, and the outer walls of the two granulating rollers 11 are rotatably connected to the granulation box 1; the outer wall of the linkage cylinder 8 is provided with a hole thickness adjustment mechanism; a positioning adjustment mechanism is installed at one end of the turntable 10.

[0031] In this embodiment, as shown in the attached Figure 1-4 As shown, a controller 13 is fixedly installed on one side of the granulation box 1, and a support frame 14 is fixedly connected to the outer wall of the granulation box 1 and located below the controller 13, so that the granulation box 1 is supported by the support frame 14, and the granulation box 1 supports the controller 13, and the controller 13 can start the electric cylinder 2, and the electric cylinder 2 pushes the linkage block 3 to realize the moving operation. Guide plates 15 are fixedly connected to both sides of the inner wall of the granulation box 1, and the guide plates 15 are rotatably connected to the outer wall of the granulation roller 11, so that the carbamazepine granulation powder raw material passes through the two guide plates 15 to guide the material into the two granulation rollers and then enters the granulation space between the two granulation rollers 11, so as to realize the guide granulation operation. A convex strip 16 is welded to the top of the outer wall of the rotating shaft 9, and the convex strip 16 is slidably connected to the inner wall of the linkage cylinder 8, so that the turntable 10 can carry the rotating shaft 9 and the convex strip 16 to rotate in a limited position. The rotating shaft 9 and the convex strip 16 can drive the linkage cylinder 8 to rotate, and the linkage cylinder 8 can slide along the outer wall of the convex strip 16.

[0032] In this embodiment, as shown in the attached Figure 5-6As shown, the hole thickness adjustment mechanism includes a plurality of guide frames 17 fixedly arranged on the outer wall of the linkage cylinder 8; the top and bottom ends of the guide frames 17 are slidably connected with slip rings 18, the inner wall of the guide frames 17 is slidably connected with a sliding shaft 19, and the inner walls of the two slip rings 18 are welded to the outer wall of the sliding shaft 19; a slider 20 is welded to the bottom end of the sliding shaft 19, and an adjustment bar 21 is fixedly installed on one side of the slider 20, and a plurality of adjustment columns 22 are fixedly connected on one side of the adjustment bar 21, and the plurality of adjustment columns 22 are arranged equidistantly from front to back; a plurality of granulation holes 23 are opened on the outer wall of the granulation roller 11, and the adjustment columns 22 are slidably connected with the granulation roller 11 to which the granulation holes 23 belong. The two slip rings 18 are symmetrically arranged about the guide frame 17, and the plurality of adjustment bars 21 are arranged equidistantly in a circular ring.

[0033] In this embodiment, as shown in the attached Figure 7-10 As shown, the positioning and adjusting mechanism includes a sensing rod 24 fixedly mounted on one end of the turntable 10; the outer wall of the sensing rod 24 is rotatably connected to the granulation box 1, and one end of the sensing rod 24 is coaxially connected to a stepping motor 25, a supporting block 26 is installed at the bottom end of the stepping motor 25, and the granulation box 1 and the stepping motor 25 are both fixedly connected to the supporting block 26; a pillar 27 fixedly connected to the granulation box 1 is provided below the collar 6, a supporting plate 28 is welded to one end of the pillar 27, and two distance sensors 29 are fixedly mounted on the inner wall of the supporting plate 28; two sleeve blocks 30 are welded to one side of the support plate 28, and a proximity sensor 31 is fixedly mounted on the inner wall of the sleeve block 30.

[0034] A linkage plate 32 is welded to one end of the adjustment bar 21, a distance sensing block 33 is fixedly connected to one end of the linkage plate 32, and a positioning sensing block 34 is fixedly installed on one side of the distance sensing block 33; the positioning sensing block 34 is fixedly connected to the linkage plate 32, and the right side surface of the distance sensing block 33 and the right end surface of the adjustment column 22 are in the same vertical plane.

[0035] The working principle of the carbamazepine compressed solid tablet granulation equipment of the present invention is as follows: First, when the present invention performs positioning adjustment, the granulation box 1 is supported by the support frame 14, and the granulation box 1 supports the controller 13. The granulation box 1 can provide support force to the support block 26, and the support block 26 provides support force to the stepping motor 25, thereby increasing the stability of the stepping motor 25. The controller 13 starts the two stepping motors 25, and the two stepping motors 25 respectively drive the two sensing rods 24, and the two sensing rods 24 rotate inside the granulation box 1. The sensing rods 24 drive the turntable 10 to rotate, the turntable 10 carries the granulation roller 11 to rotate, the granulation roller 11 carries a plurality of adjustment columns 22 to rotate, the adjustment columns 22 drive the adjustment bar 21 to rotate, the adjustment bar 21 carries the linkage plate 32 to rotate downward, and the linkage plate 32 drives the distance sensing block 33 to rotate downward.

[0036] At the same time, the distance sensing block 33 drives the positioning sensing block 34 to rotate downward. When the positioning sensing block 34 is located at the sensing position of the proximity sensor 31, the two stepping motors 25 are turned off through the controller 13. At the same time, the distance sensing block 33 is located above the distance sensor 29 and parallel to it. Another distance sensing block 33 is located above another distance sensor 29 and parallel to it. The granulating box 1 supports the pillar 27, and the pillar 27 supports the support plate 28. The support plate 28 provides a stable support force for the two distance sensors 29. At the same time, the support plate 28 supports the two sets of blocks 30, and the sets of blocks 30 support the proximity sensor 31, so that the distance sensing block 33 can be accurately moved to the upper position of the distance sensor 29.

[0037] Secondly, when the present invention performs linkage adjustment, the controller 13 starts the electric cylinder 2, the electric cylinder 2 pushes the linkage block 3 to move, the linkage block 3 drives the linkage bar 4 to move, the linkage bar 4 moves forward, the linkage bar 4 carries the two connecting blocks 5 forward, the two connecting blocks 5 can respectively drive the two shaft rings 6 to move forward synchronously, the shaft rings 6 are embedded in the outer wall of the groove cylinder 7, so that the shaft rings 6 can carry the groove cylinder 7 forward, the groove cylinder 7 carries the linkage cylinder 8 forward, the linkage cylinder 8 moves forward and slides along the outer wall of the rotating shaft 9 and the outer wall of the convex strip 16, and the turntable 10 can support the rotating shaft 9, so that the two linkage cylinders 8 can synchronously realize the sliding operation.

[0038] Then, when the present invention adjusts the hole thickness, the linkage cylinder 8 drives multiple guide frames 17 to move forward, the guide frame 17 drives the sliding shaft 19 to move forward and away from the center point of the linkage cylinder 8, the sliding shaft 19 drives the two slip rings 18 to slide along the guide frame 17, the sliding shaft 19 drives the slider 20 to move away from the center point of the linkage cylinder 8, the slider 20 drives the adjustment bar 21 to move away from the center point of the linkage cylinder 8, the adjustment bar 21 drives multiple adjustment columns 22 to move away from the center point of the linkage cylinder 8, the adjustment column 22 moves away from the center point of the linkage cylinder 8 inside the granulation hole 23, so that the adjustment column 22 adjusts the thickness of the granulation hole 23.

[0039] The granulation thickness inside the multiple granulation holes 23 is synchronously adjusted. When the adjustment bar 21 moves away from the center point of the linkage cylinder 8, the adjustment bar 21 will drive the linkage plate 32 to move away from the center point of the linkage cylinder 8, and the linkage plate 32 will drive the distance sensing block 33 to move away from the center point of the linkage cylinder 8. The distance sensing block 33 can move toward the distance sensor 29. Since the right end face of the distance sensing block 33 and the right end face of the adjustment column 22 are in the same vertical plane, when the value sensed by the distance sensor 29 and the value sensed by another distance sensor 29 are superimposed and can be the same as the granulation adjustment thickness value set by the controller 13, the electric cylinder 2 is closed by the controller 13 to complete the granulation thickness adjustment operation inside the multiple granulation holes 23.

[0040] Finally, when the present invention performs granulation, the carbamazepine granulation powder raw material is poured into the feed hopper 12, enters the granulation box 1 through the feed hopper 12, and enters the two granulation rollers through the two guide plates 15 to pour the material into the granulation space between the two granulation rollers 11. The two sensor rods 24 are synchronously started to rotate by the controller 13, the sensor rods 24 carry the turntable 10 to rotate, the turntable 10 carries the rotating shaft 9 and the convex strips 16 to rotate, the rotating shaft 9 and the convex strips 16 can drive the linkage cylinder 8 to rotate, and the linkage cylinder 8 carries the groove cylinder 7 to realize limited rotation on the inner wall of the shaft ring 6.

[0041] At the same time, the turntable 10 carries the granulating roller 11 to rotate, and the granulating roller 11 drives the multiple granulating holes 23 to rotate. The carbamazepine granulation powder raw material is filled in the granulating holes 23 under the action of the rotational force of the two granulating rollers 11, and the adjusting column 22 provides a supporting force, so that it is extruded into tablet particles in the granulating holes 23, and then swung downward by centrifugation under the action of the rotational force of the granulating roller 11 to realize the downward discharge operation of the carbamazepine tablet particles, thereby completing the carbamazepine compressed solid tablet granulation operation.

[0042] The contents not described in detail in the specification belong to the prior art known to those skilled in the art, and the model parameters of each electrical appliance are not specifically limited, and conventional equipment can be used. In this technical solution, the electrical control components not mentioned are not shown in the figure because they belong to the prior art and will not be described here.

[0043] The above are only preferred embodiments of the present invention and are not intended to limit the present invention. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention should be included in the protection scope of the present invention.

Claims

1. A granulation device for compressed solid tablets of carbamazepine, comprising a granulation box (1), an electric cylinder (2) and a linkage block (3), wherein the electric cylinder (2) is fixed in front of the granulation box (1), and the linkage block (3) is fixed on the output end of the electric cylinder (2), characterized in that: A linkage adjustment mechanism is installed at the bottom end of the linkage block (3); The linkage adjustment mechanism comprises a linkage bar (4) fixedly mounted on the bottom end of the linkage block (3), and two connection blocks (5) are welded to the bottom end of the linkage bar (4), and the bottom end of each connection block (5) is fixedly connected to a shaft ring (6); The inner wall of the collar (6) is rotatably connected to a grooved cylinder (7), and a linkage cylinder (8) is welded to one end of the grooved cylinder (7), a rotating shaft (9) is slidably connected to the inner wall of the linkage cylinder (8), a rotating disk (10) is fixedly connected to one end of the rotating shaft (9), a granulating roller (11) is fixedly connected to the outer wall of the rotating disk (10), and the outer walls of the two granulating rollers (11) are rotatably connected to the granulating box (1); The outer wall of the linkage cylinder (8) is provided with a hole thickness adjustment mechanism; A positioning adjustment mechanism is installed at one end of the turntable (10).

2. The carbamazepine compressed solid tablet granulation equipment according to claim 1, characterized in that: The two granulating rollers (11) are rotatably connected, and the vertical cross-section of the granulating roller (11) is set to be in the shape of a circular ring.

3. The carbamazepine compressed solid tablet granulation equipment according to claim 1, characterized in that: A feed hopper (12) is fixedly connected to the top of the granulation box (1), and the feed hopper (12) is in communication with the granulation box (1); The inner wall of the feed hopper (12) of the granulation box (1) is configured as a smooth surface.

4. The carbamazepine compressed solid tablet granulation equipment according to claim 1, characterized in that: A controller (13) is fixedly mounted on one side of the granulation box (1), and a support frame (14) is fixedly connected to the outer wall of the granulation box (1) at a position below the controller (13).

5. The carbamazepine compressed solid tablet granulation equipment according to claim 1, characterized in that: Guide plates (15) are fixedly connected to both sides of the inner wall of the granulating box (1), and the guide plates (15) are rotatably connected to the outer wall of the granulating roller (11).

6. The carbamazepine compressed solid tablet granulation equipment according to claim 1, characterized in that: A convex strip (16) is welded to the top end of the outer wall of the rotating shaft (9), and the convex strip (16) is slidably connected to the inner wall of the linkage cylinder (8).

7. The carbamazepine compressed solid tablet granulation equipment according to claim 1, characterized in that: The hole thickness adjustment mechanism comprises a plurality of guide frames (17) fixedly arranged on the outer wall of the linkage cylinder (8); The top and bottom ends of the guide frame (17) are slidably connected to a slip ring (18), the inner wall of the guide frame (17) is slidably connected to a sliding shaft (19), and the inner walls of the two slip rings (18) are welded to the outer wall of the sliding shaft (19); A slider (20) is welded to the bottom end of the sliding shaft (19), and an adjustment bar (21) is fixedly mounted on one side of the slider (20), and a plurality of adjustment columns (22) are fixedly connected to one side of the adjustment bar (21), and the plurality of adjustment columns (22) are arranged in sequence and equidistantly from front to back; The outer wall of the granulating roller (11) is provided with a plurality of granulating holes (23), and the adjusting column (22) is slidably connected to the granulating roller (11) to which the granulating holes (23) belong.

8. The carbamazepine compressed solid tablet granulation equipment according to claim 7, characterized in that: The two slip rings (18) are symmetrically arranged with respect to the guide frame (17), and the plurality of adjustment strips (21) are arranged in a circular ring and are equidistantly distributed.

9. The carbamazepine compressed solid tablet granulation equipment according to claim 1, characterized in that: The positioning adjustment mechanism comprises a sensing rod (24) fixedly mounted on one end of the rotating disk (10); The outer wall of the sensing rod (24) is rotatably connected to the granulation box (1), and one end of the sensing rod (24) is coaxially connected to a stepping motor (25), a supporting block (26) is installed at the bottom end of the stepping motor (25), and the granulation box (1) and the stepping motor (25) are both fixedly connected to the supporting block (26); A support (27) fixedly connected to the granulation box (1) is provided below the collar (6); a support plate (28) is welded to one end of the support plate (27); and two distance sensors (29) are fixedly mounted on the inner wall of the support plate (28); Two sleeve blocks (30) are welded to one side of the support plate (28), and a proximity sensor (31) is fixedly mounted on the inner wall of the sleeve block (30).

10. The carbamazepine compressed solid tablet granulation equipment according to claim 7, characterized in that: A linkage plate (32) is welded to one end of the adjustment bar (21), a distance sensing block (33) is fixedly connected to one end of the linkage plate (32), and a positioning sensing block (34) is fixedly mounted on one side of the distance sensing block (33); The positioning sensing block (34) is fixedly connected to the linkage plate (32), and the right side surface of the distance sensing block (33) and the right end surface of the adjustment column (22) are located in the same vertical plane.

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