Modularized chemical synthesis experiment system

Abstract

The invention provides a modular chemical synthesis experiment system, and relates to the technical field of chemical engineering, an electrical module is installed in an electrical cavity formed in an integrated base, the electrical module is detachably connected with the integrated base, the types of the electrical module are increased or decreased or replaced according to experiment requirements, an experiment module is detachably installed on the integrated base, and the electrical module is detachably connected with the integrated base. The types of experiment modules are increased or decreased or replaced according to experiment requirements, the system is suitable for different chemical reactions and flows, the system can be easily expanded, more modules can be increased or parallel work can be carried out, maintenance and troubleshooting of the system are simpler and quicker, and the problems that in the prior art, a chemical synthesis system is complex in design and operation, and the working efficiency is high are solved. And the method is difficult to adapt to special or unconventional chemical reactions and processes.

Description

Technical Field

[0001] The invention relates to the technical field of chemical engineering, and in particular to a modular chemical synthesis experimental system. Background Art

[0002] Chemical synthesis automation system refers to a system that uses automatic control technology, robotics technology, etc. to realize the functions of automated operation, data collection and analysis of the reaction process in chemical synthesis experiments. Such systems can improve the efficiency, accuracy and safety of chemical synthesis, bringing changes to fields such as chemical research and drug development.

[0003] Some of the shortcomings of the current chemical synthesis system mainly include:

[0004] (1) Complexity: The design and operation of chemical automated synthesis systems are often complex and require technical knowledge in interdisciplinary fields such as chemistry, chemical engineering, mechanics, fluids, electronics, and software.

[0005] (2) Flexibility limitations: Currently, most chemical synthesis experimental systems are customized in design. It is difficult to migrate and reconstruct the synthesis experiments of new molecules, and it is difficult to adapt to special or unconventional chemical reactions and processes.

[0006] (3) Scale adaptability: Automated systems are often more suitable for large-scale production. For small-scale or laboratory-scale synthesis, these systems may not be as efficient as manual operations, and the systems may still be difficult to adapt to special or unconventional chemical reactions and processes. Summary of the invention

[0007] The purpose of the present invention is to provide a modular chemical synthesis experimental system to alleviate the technical problems existing in the prior art that the chemical synthesis system design and operation are relatively complex and difficult to adapt to special or unconventional chemical reactions and processes.

[0008] The modular chemical synthesis experimental system provided by the present invention comprises: an integrated base, an electrical module, an experimental module and a mobile module;

[0009] An electrical chamber is formed inside the integrated base, the electrical module is arranged in the electrical chamber, and the electrical module is detachably connected to the inner wall of the integrated base;

[0010] The experimental module is arranged on the outer surface of the integrated base, and the experimental module is detachably connected to the integrated base;

[0011] The mobile module is arranged above the experimental module, and the mobile module is configured to be movable relative to the experimental module so that the experimental module can complete a sampling operation or a sample adding operation.

[0012] In an alternative embodiment,

[0013] The experimental module includes a reaction module;

[0014] The reaction module comprises a reaction box and a reaction kettle;

[0015] The reaction box is detachably connected to the integrated base, and the reaction kettle is arranged on the reaction box. The reaction kettle is used to hold liquid samples and / or solid samples.

[0016] In an alternative embodiment,

[0017] The reaction module also includes a reaction stirring component and a reaction heating component;

[0018] The reaction stirring member is connected to the reaction box, and the stirring driving end of the reaction stirring member extends into the reaction kettle;

[0019] The reaction heating component is disposed in the reaction box, and the reaction heating component is configured to heat the reaction kettle.

[0020] In an alternative embodiment,

[0021] The experimental module also includes a solid sample addition module;

[0022] The solid sample loading module contains solid samples, and the moving module is used to drive the solid samples in the solid sample loading module to move.

[0023] In an alternative embodiment,

[0024] The solid loading module comprises a solid loading base, a loading rack, a powder loading head and a solid loading driving component;

[0025] The solid sample loading base is detachably connected to the integrated base, the sample loading rack is arranged on the solid sample loading base, and the solid sample loading driving component and the plurality of powder sample loading heads are placed on the sample loading rack;

[0026] The solid loading driving member is configured to be capable of being drivingly connected to the powder loading head so as to cause the powder in the powder loading head to fall;

[0027] The moving module is configured to drive the solid sample loading driving component to move, so that the solid sample loading driving component is drivingly connected to the powder sample loading head.

[0028] In an alternative embodiment,

[0029] The moving module is configured to drive the solid loading driving member and the powder loading head to move to the top of the reaction kettle, so that the powder in the powder loading head falls into the reaction kettle to complete the powder loading operation.

[0030] In an alternative embodiment,

[0031] The powder loading head comprises a powder loading housing, an anti-blocking threaded rod, a transmission assembly and a conveying screw rod;

[0032] The powder adding shell is formed with a powder inner cavity for placing powder, and the powder adding shell is formed with a powder conveying cavity connected with the bottom of the powder inner cavity, and the powder adding shell is provided with a powder outlet, and the powder outlet is connected with the powder conveying cavity;

[0033] The anti-blocking threaded rod is arranged in the powder loading housing, one end of the anti-blocking threaded rod extends into the powder inner cavity, the other end of the anti-blocking threaded rod is connected to the transmission assembly, and the anti-blocking threaded rod is configured to be able to rotate along its own axis to drive the powder in the powder inner cavity to fall into the powder conveying cavity;

[0034] One end of the conveying screw rod extends into the powder conveying chamber, and the other end of the conveying screw rod extends from the powder loading housing and can be transmission-connected with the solid loading driving component, and the conveying screw rod is connected to the transmission assembly, and the solid loading driving component is used to drive the conveying screw rod to rotate along its own axis direction, so as to drive the powder in the powder conveying chamber to fall out from the powder outlet;

[0035] The transmission assembly is used to make the conveying screw rod and the anti-blocking threaded rod rotate synchronously.

[0036] In an alternative embodiment,

[0037] The solid sample loading module also includes a weighing platform;

[0038] The weighing platform is detachably connected to the integrated base, a moving plate is slidably connected to the top surface of the weighing platform, a placing platform is provided on the moving plate, a material drop opening is provided on the placing platform, and the powder outlet of the powder dosing head placed on the placing platform can be connected to the material drop opening, so that the powder in the powder dosing head can fall into the balance container inside the weighing platform;

[0039] The moving module is configured to drive the solid loading driving member and the powder loading head to move to the placement table together, so that the powder outlet is connected to the drop port.

[0040] In an alternative embodiment,

[0041] The experimental module also includes a liquid sample adding module;

[0042] The liquid sample adding module contains liquid samples, and the moving module is used to drive the liquid samples in the liquid sample adding module to move into the reaction kettle.

[0043] In an alternative embodiment,

[0044] The liquid sample adding module comprises a liquid pump assembly;

[0045] The pump liquid assembly comprises a liquid sample adding base, a plunger pump, a buffer bottle and a switching valve;

[0046] The liquid sample loading base comprises an upper support and a lower support that are connected to each other, the lower support is detachably connected to the integrated base, and a plurality of reagent bottles are placed on the lower support;

[0047] The plunger pump and the switching valve are both installed on the upper support;

[0048] The reaction kettle and the plurality of reagent bottles are arranged in parallel and are connected to the switching valve;

[0049] The plunger pump is connected to the switching valve pipeline, the buffer bottle is arranged on the pipeline between the plunger pump and the switching valve, and the switching valve is used to control the connection and disconnection between the reactor and the buffer bottle, and control the connection and disconnection between the plurality of reagent bottles and the buffer bottle;

[0050] The plunger pump is configured to be able to suck the liquids in the plurality of reagent bottles into the buffer bottle, and to be able to pump the liquids in the buffer bottle into the reactor.

[0051] In an alternative embodiment,

[0052] The liquid loading module also includes a pipetting component;

[0053] The pipetting assembly includes a pipetting base, a pipetting gun recovery box, a pipetting gun rack and a pipetting gun box;

[0054] The pipetting base is detachably connected to the integrated base, and the pipetting gun recovery box, the pipetting gun rack and the pipetting gun box are all arranged on the pipetting base;

[0055] The pipette gun box stores a pipette gun component, and the moving module is configured to be able to grab the pipette gun component in the pipette gun box and drive the pipette gun component to move, so that the pipette gun component absorbs the liquid sample in the reagent bottle and drips it into the reactor;

[0056] The pipette gun rack is used to hang the pipette gun component;

[0057] The pipette recovery box is used to recover the pipette components after use.

[0058] In an alternative embodiment,

[0059] The electrical module includes at least one of a power module, a communication module, a vacuum module, a water separation module and a gas separation module.

[0060] The modular chemical synthesis experimental system provided by the present invention has an electrical module installed in an electrical chamber formed inside an integrated base, and the electrical module is detachably connected to the integrated base. The types of electrical modules can be increased, decreased or replaced according to experimental requirements. The experimental module is detachably installed on the integrated base. The types of experimental modules can be increased, decreased or replaced according to experimental requirements. The system is suitable for different chemical reactions and processes, and the system can be easily expanded to add more modules or work in parallel. The maintenance and troubleshooting of the system are also simpler and faster, which alleviates the technical problems in the prior art that the chemical synthesis system design and operation are relatively complex and difficult to adapt to special or unconventional chemical reactions and processes. BRIEF DESCRIPTION OF THE DRAWINGS

[0061] In order to more clearly illustrate the specific implementation methods of the present invention or the technical solutions in the prior art, the drawings required for use in the specific implementation methods or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are some implementation methods of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0062] Figure 1 A schematic diagram of the overall structure of a modular chemical synthesis experimental system provided by an embodiment of the present invention;

[0063] Figure 2 A schematic diagram of the structure of a modular chemical synthesis experiment system from a top view provided by an embodiment of the present invention;

[0064] Figure 3 A schematic diagram of the area division of a modular chemical synthesis experiment system provided by an embodiment of the present invention;

[0065] Figure 4 A schematic diagram of the layout of a modular chemical synthesis experimental system provided by an embodiment of the present invention;

[0066] Figure 5 A schematic diagram of the structure of a reaction module in a modular chemical synthesis experimental system provided in an embodiment of the present invention;

[0067] Figure 6 A schematic diagram of the structure of a solid sample loading module in a modular chemical synthesis experimental system provided in an embodiment of the present invention;

[0068] Figure 7 A schematic diagram of the structure of a powder loading head in a modular chemical synthesis experimental system provided by an embodiment of the present invention;

[0069] Figure 8 A schematic diagram of the structure of a pump assembly in a modular chemical synthesis experimental system provided by an embodiment of the present invention;

[0070] Fig. 9 A schematic diagram of the structure of a liquid transfer component in a modular chemical synthesis experimental system provided in an embodiment of the present invention;

[0071] Fig.10 A schematic structural diagram of an electrical module and an integrated base in a modular chemical synthesis experimental system provided by an embodiment of the present invention.

[0072] Icons: 100-integrated base; 200-electrical module; 210-power module; 220-communication module; 230-water distribution module; 240-gas distribution module; 300-experimental module; 310-reaction module; 311-reaction box; 312-reactor; 313-reaction stirring component; 314-reaction heating component; 320-solid loading module; 321-solid loading base; 322-loading rack; 323-powder loading head; 3231-powder loading shell; 3232-anti-blocking threaded rod; 3233-transmission assembly; 3234 - conveying screw rod; 324- solid sample loading drive component; 325- weighing table; 326- moving plate; 327- placing table; 328- dropping port; 330- liquid sample loading module; 331- liquid sample loading base; 332- plunger pump; 333- switching valve; 334- pipetting base; 335- pipette recovery box; 336- pipette rack; 337- pipette box; 338- buffer bottle holder; 339- reagent bottle; 400- moving module; 410- X-axis slide rail; 420- Y-axis slide rail; 430- Z-axis slide rail; 440- gripper component. DETAILED DESCRIPTION

[0073] The technical solution of the present invention will be described clearly and completely below in conjunction with the accompanying drawings. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0074] In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc., indicating the orientation or positional relationship, are based on the orientation or positional relationship shown in the drawings, and are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as limiting the present invention. In addition, the terms "first", "second", and "third" are used for descriptive purposes only, and cannot be understood as indicating or implying relative importance.

[0075] In the description of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "installed", "connected", and "connected" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be indirectly connected through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0076] The specific implementation of the present invention is described in detail below in conjunction with the accompanying drawings. It should be understood that the specific implementation described here is only used to illustrate and explain the present invention, and is not used to limit the present invention.

[0077] like Figure 1 , Figure 2 As shown, the modular chemical synthesis experimental system provided in this embodiment includes: an integrated base 100, an electrical module 200, an experimental module 300 and a mobile module 400; Figure 3 As shown, the whole experimental system is divided into three areas: upper, middle and lower. The lowest part is the integrated base 100 area. The integrated base 100 is a box-type structure. The interior of the integrated base 100 forms an electrical chamber, such as Fig.10As shown, the electrical module 200 is arranged in the electrical chamber, and the side wall of the integrated base 100 is provided with an opening which can be used as an interface for gas circuit, communication and circuit. The electrical module 200 specifically includes at least one of a water distribution module 230, a gas distribution module 240, a vacuum module, a communication module 220 and a power module 210, and provides corresponding basic settings such as water, gas, electricity and communication for the experimental module 300 on the integrated base 100. The specific type of the electrical module 200 is selected according to the experimental needs, and since the electrical module is detachably connected to the inner wall of the integrated base 100, the specific type of the electrical module 200 can be freely replaced, and the subsequent maintenance of the electrical module 200 is convenient. The middle part is the synthetic experimental area, where the solid sample loading module 320, the liquid sample loading module 330 and the reaction module 310 can be placed. The uppermost part is the moving area of ​​the robot module, which can be a robot arm movement or a multi-axis module movement. It is particularly worth noting that the interference problem between the robot module and the synthetic experimental area should be considered in detail when the module is assembled.

[0078] The middle area of ​​the overall experimental system is the synthetic experimental area. The experimental module 300 is located in the synthetic experimental area. The experimental module 300 is arranged on the outer surface of the integrated base 100, and the experimental module 300 is detachably connected to the integrated base 100 to facilitate the disassembly and assembly of the experimental module 300. The specific type of the experimental module 300 is selected according to the experimental needs.

[0079] It should be noted that the electrical module 200 in the integrated base 100 and the experimental module 300 on the integrated base 100 need to be arranged in a plane plan, for example Figure 4 As shown, each module in the experimental module 300 has three sizes, module size type 1 is a square with a side length of 200 mm, module size type 2 is a rectangle with a length of 400 mm and a width of 200 mm, and module size 3 is a positive direction with a side length of 400 mm. The three sizes are combined and pieced together into a rectangle according to the number of uses, making the overall system more compact.

[0080] The upper area of ​​the overall experimental system is a mobile area, and the mobile module 400 is located in the mobile area. The mobile module 400 is set above the experimental module 300. The mobile module 400 is configured to be able to move relative to the experimental module 300 so that the experimental module 300 completes the sampling operation or the sample addition operation.

[0081] Specifically, the mobile module 400 can be set as a manipulator or a three-axis gripper assembly. Preferably, the mobile module 400 is set as a three-axis gripper assembly, which includes an X-axis slide rail 410, a Y-axis slide rail 420, a Z-axis slide rail 430 and a gripper member 440. The X-axis slide rail 410 is arranged along a first direction, the Y-axis slide rail 420 is arranged along a second direction, and the Z-axis slide rail 430 is arranged along a third direction. The first direction, the second direction and the third direction are arranged perpendicular to each other to form a three-axis movement. The X-axis slide rail 410 is supported by a support frame. Supported above the experimental module 300, the Y-axis slide rail 420 is slidably connected to the X-axis slide rail 410 so that the Y-axis slide rail 420 can move along the X-axis slide rail 410, the Z-axis slide rail 430 is slidably connected to the Y-axis slide rail 420 so that the Z-axis slide rail 430 can move along the Y-axis slide rail 420, and the gripping member 440 is slidably connected to the Z-axis slide rail 430 so that the gripping member 440 can move along the Z-axis slide rail 430, thereby realizing the three-axis movement of the gripping member 440 and realizing automated sampling or adding operations.

[0082] In an optional embodiment, if Figure 5 As shown, the experimental module 300 includes a reaction module 310; the reaction module 310 includes a reaction box 311 and a reaction kettle 312, the reaction box 311 is specifically a box-type structure, the bottom wall of the reaction box 311 is detachably connected to the integrated base 100, and the detachable connection between the reaction box 311 and the integrated base 100 can be achieved by bolts, the reaction base is provided with a placement groove, the notch of the placement groove faces upward, the reaction kettle 312 is placed in the placement groove, and the top opening of the reaction kettle 312 protrudes from the top of the reaction base, the reaction kettle 312 is used to hold liquid samples and / or solid samples to achieve chemical reactions in the reaction kettle 312.

[0083] In an optional embodiment, the reaction module 310 also includes a reaction stirring component 313 and a reaction heating component 314; the reaction stirring component 313 is connected to the reaction box 311, specifically, a support column is provided on the top surface of the reaction box 311, a support plate is fixed on the support column, the reaction stirring component 313 includes a driving motor and a stirring member, the driving motor is installed on the support plate, the driving shaft of the driving motor is connected to the stirring member, the stirring member extends into the reactor 312, and the driving force generated by the driving motor drives the stirring member to rotate, so that the stirring member stirs the liquid in the reactor 312.

[0084] Optionally, the reaction module 310 is further provided with a reaction heating component 314, which is arranged in the reaction box 311. The reaction heating component 314 is configured to heat the reaction kettle 312. The reaction heating component 314 is an existing product, and the specific type and structure of the reaction heating component 314 are selected according to actual conditions.

[0085] In addition, the reaction module 310 may also be provided with a reaction cooling component, which is arranged in the reaction box 311 and is used to cool the reaction kettle 312. The reaction cooling component is an existing product, and the specific type and structure of the reaction cooling component are selected according to actual conditions.

[0086] In an optional embodiment, if Figure 6 As shown, the experimental module 300 further includes a solid sample loading module 320 ; the solid sample loading module 320 contains solid samples, and the moving module 400 is used to drive the solid samples in the solid sample loading module 320 to move, thereby completing the solid sample loading operation.

[0087] Regarding the structure and shape of the solid sample loading module 320, specifically:

[0088] The solid loading module 320 includes a solid loading base 321 , a loading rack 322 , a powder loading head 323 and a solid loading driving member 324 .

[0089] The solid loading base 321 is detachably connected to the integrated base 100. The solid loading base 321 is a plate-like structure. The solid loading base 321 can be detachably connected to the integrated base 100 by bolts. The loading rack 322 is arranged on the solid loading base 321. The solid loading drive component 324 and multiple powder loading heads 323 are all placed on the loading rack 322.

[0090] The solid loading drive component 324 is configured to be transmission-connected with the powder loading head 323 so that the powder in the powder loading head 323 falls. It should be noted that only one solid loading drive component 324 may be provided, while a plurality of powder loading heads 323 may be provided. The solid loading drive component 324 is driven to move by the moving module 400, so that the solid loading drive component 324 can be selectively transmission-connected with the powder loading head 323.

[0091] Regarding the structure and shape of the powder adding head 323, specifically:

[0092] like Figure 7 As shown, the powder loading head 323 includes a powder loading housing 3231, an anti-blocking threaded rod 3232, a transmission assembly 3233 and a conveying screw rod 3234;

[0093] The powder loading shell 3231 is a box-type structure, and a powder cavity for placing powder is formed in the powder loading shell 3231. The powder cavity is a funnel-shaped structure, and the opening size at the top of the powder cavity is larger than the opening size at the bottom of the powder cavity. A powder conveying cavity connected with the bottom of the powder cavity is formed in the powder loading shell 3231. The powder loading shell 3231 is provided with a powder outlet, and the powder outlet is connected with the powder conveying cavity. The powder sample in the powder cavity freely falls into the powder conveying cavity, and the powder sample in the powder conveying cavity is discharged through the powder outlet.

[0094] In order to prevent the powder sample in the powder cavity from being blocked, an anti-blocking threaded rod 3232 is provided. The anti-blocking threaded rod 3232 is arranged in the powder loading shell 3231. One end of the anti-blocking threaded rod 3232 extends into the powder cavity, and the other end of the anti-blocking threaded rod 3232 is connected to the transmission assembly 3233. The anti-blocking threaded rod 3232 is configured to be able to rotate along its own axis, so that the threaded ribs on the surface of the anti-blocking threaded rod 3232 rotate, driving the powder in the powder cavity to fall into the powder conveying cavity, thereby ensuring that the powder sample in the powder cavity can smoothly enter the powder conveying cavity.

[0095] One end of the conveying screw rod 3234 extends into the powder conveying chamber, and the other end of the conveying screw rod 3234 extends from the powder loading housing 3231 and can be connected to the solid loading drive component 324 for transmission, and the conveying screw rod 3234 is connected to the transmission assembly 3233. The solid loading drive component 324 is used to drive the conveying screw rod 3234 to rotate along its own axial direction to drive the powder in the powder conveying chamber to fall out from the powder outlet.

[0096] Specifically, a spline is provided at one end of the conveying screw rod 3234 extending out of the powder loading housing 3231, and a spline groove is provided on the driving shaft of the solid loading drive component 324. The torque and torque are transmitted by the cooperation of the spline and the spline groove, thereby realizing the transmission connection between the conveying screw rod 3234 and the solid loading drive component 324.

[0097] The transmission assembly 3233 is used to make the conveying screw rod 3234 and the anti-blocking threaded rod 3232 rotate synchronously. Specifically, the transmission assembly 3233 includes a first transmission gear and a second transmission gear. The first transmission gear is sleeved on the anti-blocking threaded rod 3232, and the first transmission gear is fixedly connected to the anti-blocking threaded rod 3232. The second transmission gear is sleeved on the conveying screw rod 3234, and the second transmission gear is fixedly connected to the conveying screw rod 3234. The first transmission gear and the second transmission gear are meshed and connected, so that when the conveying screw rod 3234 is driven to rotate by the solid sample loading driving component 324, the anti-blocking threaded rod 3232 is driven to rotate synchronously by the first transmission gear and the second transmission gear, so that only one driving component is used to drive the anti-blocking threaded rod 3232 and the conveying screw rod 3234 to rotate together at the same time.

[0098] In an optional embodiment, the solid loading module 320 also includes a weighing table 325; the weighing table 325 is a box-type structure, the bottom of the weighing table 325 is detachably connected to the integrated base 100, and the top surface of the weighing table 325 is slidably connected to a movable plate 326, and the movable plate 326 can slide relative to the weighing table 325, and a placement table 327 is provided on the movable plate 326, and the placement table 327 is provided with a drop port 328. The moving module 400 can drive the solid loading drive component 324 and the powder loading head 323 to move to the placement table 327 together, so that the powder outlet is connected to the drop port 328, so that the powder in the powder loading head 323 can fall into the balance container inside the weighing table 325. When it is necessary to take out the powder sample on the balance container, the movable plate 326 is driven to move so that the top of the weighing table 325 has an opening, so that the pipette gun component can extend into the weighing table 325 to take out the powder sample on the balance container.

[0099] After the solid loading driving component 324 is connected to the powder loading head 323 by transmission, powder loading can be realized in two ways. Method 1: the moving module 400 drives the solid loading driving component 324 and the powder loading head 323 to move to the top of the reactor 312, and the solid loading driving component 324 is started to make the powder in the powder loading head 323 fall into the reactor 312 to complete the powder loading operation. After the loading is completed, the moving module 400 puts the powder loading head 323 and the solid loading driving component 324 back to their original positions. Method 2: the moving module 400 drives the solid loading driving component 324 and the powder loading head 323 moves to the weighing platform 325 together, the solid sampling driving component 324 is started, so that the powder in the powder sampling head 323 can fall into the balance container inside the weighing platform 325, and the mobile module 400 grabs the pipette gun component after moving, so that the pipette gun component absorbs the liquid, and then adds it into the balance container to prepare the suspension, and the mobile module 400 drives the pipette gun component with the suspension to move to the top of the reactor 312 for sampling. After the sampling is completed, the mobile module 400 puts the powder sampling head 323 and the solid sampling driving component 324 back to their original positions, and places the pipette gun component into the pipette gun recovery box 335.

[0100] In an optional embodiment, the experimental module 300 further includes a liquid loading module 330 ; the liquid loading module 330 contains liquid samples, and the moving module 400 is used to drive the liquid samples in the liquid loading module 330 to move to the reaction vessel 312 .

[0101] Regarding the structure and shape of the liquid sample adding module 330, specifically:

[0102] like Figure 8As shown, the liquid loading module 330 includes a pump liquid assembly; the pump liquid assembly includes a liquid loading base 331, a plunger pump 332, a buffer bottle and a switching valve 333; the liquid loading base 331 includes an upper support and a lower support that are interconnected, the lower support is detachably connected to the integrated base 100, a plurality of reagent bottles 339 are placed on the lower support, the upper support is provided with a buffer bottle bracket 338, and the buffer bottle is supported by a buffer flat bracket, the plunger pump 332 and the switching valve 333 are both installed on the upper support, and through the setting of the upper bracket and the lower bracket, an upper and lower double-layer structure is formed, the structure is more compact, and the plane space is saved.

[0103] The reactor 312 and multiple reagent bottles 339 are all arranged in parallel and are all connected to the switching valve 333. The plunger pump 332 is connected to the switching valve 333 in a pipeline. The buffer bottle is arranged on the pipeline between the plunger pump 332 and the switching valve 333. The switching valve 333 is used to control the connection and disconnection between the reactor 312 and the buffer bottle, and to control the connection and disconnection between the multiple reagent bottles 339 and the buffer bottle. The plunger pump 332 is configured to be able to suck the liquid in the multiple reagent bottles 339 into the buffer bottle, and to be able to pump the liquid in the buffer bottle into the reactor 312.

[0104] For example, when it is necessary to pump the liquid in the first reagent bottle 339 into the reactor 312, the switching valve 333 is switched to a state in which the first reagent bottle 339 is connected to the buffer bottle, and the plunger pump 332 is started to pump the liquid sample in the first reagent bottle 339 into the buffer bottle. After the suction is completed, the switching valve 333 is switched to a state in which the buffer bottle is connected to the reactor 312, and the plunger pump 332 is started to pump the liquid sample in the buffer bottle into the reactor 312 to complete the liquid sampling.

[0105] Due to the setting of the buffer bottle and the switching valve 333, the liquids in different reagent bottles 339 can be mixed in the buffer bottle, and the mixed liquid is then pumped into the reactor 312. In addition, during the process of pumping liquid, the plunger pump 332 pumps the liquid in the reagent bottle 339 into the buffer bottle instead of the liquid entering the plunger pump 332, thereby effectively preventing the plunger pump 332 from being corroded by the liquid. Therefore, the buffer bottle not only plays the role of mixing liquids, but also effectively prevents the plunger pump 332 from being corroded.

[0106] In addition, it should be noted that, optionally, the reagent bottle 339 is sealed. Since the reagent bottle 339 is sealed, when the plunger pump 332 sucks the liquid in the reagent bottle 339, the gas in the reagent bottle 339 gradually decreases, resulting in the liquid in the reagent bottle 339 being unable to be sucked. Therefore, a ventilation line can be inserted into the reagent bottle 339 to introduce protective gas into the reagent bottle 339, and a solenoid valve can be set on the ventilation line to control the on-off of the ventilation line.

[0107] In an optional embodiment, if Fig. 9As shown, the liquid loading module 330 also includes a pipetting assembly; the pipetting assembly includes a pipetting base 334, a pipette gun recovery box 335, a pipette gun hanger 336 and a pipette gun box 337; the pipette base 334 is a plate-like structure, and the pipette base 334 can be detachably connected to the integrated base 100 by bolts, and the pipette gun recovery box 335, the pipette gun hanger 336 and the pipette gun box 337 are all arranged on the pipetting base 334.

[0108] The pipette box 337 stores a plurality of pipette components. The mobile module 400 can grab the pipette components in the pipette box 337 and drive the pipette components to move, so that the pipette components absorb the liquid sample in the reagent bottle 339 and drip it into the reaction kettle 312. The pipette bracket 336 can hang the pipette components to facilitate the use of the pipette components. After use, the pipette components are moved to the pipette recovery box 335 by the mobile module 400 to recover the used pipette components.

[0109] When using the modular chemical synthesis experimental system provided in this embodiment, one or two modules can be used separately in the above manner, or all modules can be used. When all modules are used, solid sampling can adopt the above-mentioned powder sampling method 1, directly adding samples to the reactor 312, or adopt the above-mentioned powder sampling method 2, after weighing, a suspension is configured on the weighing table 325, and then the suspension is added to the reactor 312 using a pipette gun component; liquid sampling can adopt the plunger pump 332 to pump the liquid sample into the reactor 312, or the pipette gun component can be used to suck the liquid sample in the reagent bottle 339 and drip it into the reactor 312; the liquid and solid in the reactor 312 are mixed and reacted, and heating, cooling or stirring can be performed during the reaction process. It should be noted that mixing, heating, cooling or stirring can be selected according to the experimental situation; after the reaction is completed, the liquid in the reactor 312 is transferred by the plunger pump 332, or the pipette gun component can be used to transfer the liquid.

[0110] The modular chemical synthesis experimental system provided in this embodiment has the following advantages:

[0111] (1) From the functional realization level, it can cover solid sample addition, liquid sample addition, reaction heating, temperature control, stirring, atmosphere protection, etc.;

[0112] (2) In terms of flexibility, modules can be added, removed or replaced according to experimental requirements to adapt to different chemical reactions and processes;

[0113] (3) Scalability: As research needs grow, the system can be easily expanded by adding more modules or parallel workstations;

[0114] (4) Easy maintenance: Due to the modular design, system maintenance and troubleshooting are usually simpler and faster.

[0115] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit it. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the aforementioned embodiments, or replace some or all of the technical features therein by equivalents. However, these modifications or replacements do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of the present invention.

Claims

1. A modular chemical synthesis experimental system, characterized in that: include: An integrated base (100), an electrical module (200), an experimental module (300) and a mobile module (400); An electrical chamber is formed inside the integrated base (100), the electrical module (200) is arranged in the electrical chamber, and the electrical module (200) is detachably connected to the inner wall of the integrated base (100); The experimental module (300) is arranged on the outer surface of the integrated base (100), and the experimental module (300) is detachably connected to the integrated base (100); The movable module (400) is disposed above the experimental module (300), and the movable module (400) is configured to be movable relative to the experimental module (300) so as to enable the experimental module (300) to complete a sampling operation or a sample addition operation.

2. The modular chemical synthesis experimental system according to claim 1, characterized in that: The experimental module (300) includes a reaction module (310); The reaction module (310) includes a reaction box (311) and a reaction kettle (312); The reaction box (311) is detachably connected to the integrated base (100), and the reaction kettle (312) is arranged on the reaction box (311). The reaction kettle (312) is used to contain liquid samples and / or solid samples.

3. The modular chemical synthesis experimental system according to claim 2, characterized in that: The reaction module (310) further comprises a reaction stirring component (313) and a reaction heating component (314); The reaction stirring member (313) is connected to the reaction box (311), and the stirring driving end of the reaction stirring member (313) extends into the reaction kettle (312); The reaction heating component (314) is disposed in the reaction box (311), and the reaction heating component (314) is configured to heat the reaction kettle (312).

4. The modular chemical synthesis experimental system according to claim 2, characterized in that: The experimental module (300) further includes a solid sample adding module (320); The solid sample loading module (320) contains a solid sample, and the moving module (400) is used to drive the solid sample in the solid sample loading module (320) to move.

5. The modular chemical synthesis experimental system according to claim 4, characterized in that: The solid sample loading module (320) comprises a solid sample loading base (321), a sample loading rack (322), a powder sample loading head (323) and a solid sample loading driving component (324); The solid sample loading base (321) is detachably connected to the integrated base (100), the sample loading rack (322) is arranged on the solid sample loading base (321), and the solid sample loading drive component (324) and the plurality of powder sample loading heads (323) are placed on the sample loading rack (322); The solid loading driving member (324) is configured to be capable of being drivingly connected to the powder loading head (323) so as to cause the powder in the powder loading head (323) to fall off; The moving module (400) is configured to be able to drive the solid sample loading driving component (324) to move, so that the solid sample loading driving component (324) is drivingly connected to the powder sample loading head (323).

6. The modular chemical synthesis experimental system according to claim 5, characterized in that: The moving module (400) is configured to drive the solid loading driving component (324) and the powder loading head (323) to move to the top of the reaction kettle (312) so that the powder in the powder loading head (323) falls into the reaction kettle (312) to complete the powder loading operation.

7. The modular chemical synthesis experimental system according to claim 5, characterized in that: The powder loading head (323) comprises a powder loading housing (3231), an anti-blocking threaded rod (3232), a transmission assembly (3233) and a conveying screw rod (3234); The powder loading shell (3231) is formed with a powder inner cavity for placing powder, and the powder loading shell (3231) is formed with a powder conveying cavity connected to the bottom of the powder inner cavity, and the powder loading shell (3231) is provided with a powder outlet, and the powder outlet is connected to the powder conveying cavity; The anti-blocking threaded rod (3232) is arranged in the powder loading housing (3231), one end of the anti-blocking threaded rod (3232) extends into the powder inner cavity, and the other end of the anti-blocking threaded rod (3232) is connected to the transmission assembly (3233), and the anti-blocking threaded rod (3232) is configured to be able to rotate along its own axis to drive the powder in the powder inner cavity to fall into the powder conveying cavity; One end of the conveying screw rod (3234) extends into the powder conveying chamber, and the other end of the conveying screw rod (3234) extends from the powder loading housing (3231) and can be transmission-connected with the solid loading drive component (324), and the conveying screw rod (3234) is connected to the transmission component (3233), and the solid loading drive component (324) is used to drive the conveying screw rod (3234) to rotate along its own axis direction, so as to drive the powder in the powder conveying chamber to fall out from the powder outlet; The transmission assembly (3233) is used to enable the conveying screw rod (3234) and the anti-blocking threaded rod (3232) to rotate synchronously.

8. The modular chemical synthesis experimental system according to claim 7, characterized in that: The solid sample loading module (320) further includes a weighing platform (325); The weighing platform (325) is detachably connected to the integrated base (100); a moving plate (326) is slidably connected to the top surface of the weighing platform (325); a placing platform (327) is provided on the moving plate (326); the placing platform (327) is provided with a material drop opening (328); the powder outlet of the powder loading head (323) placed on the placing platform (327) can be connected to the material drop opening (328), so that the powder in the powder loading head (323) can fall into the balance container inside the weighing platform (325); The moving module (400) is configured to drive the solid loading drive component (324) and the powder loading head (323) to move onto the placement platform (327) so that the powder outlet is connected to the drop port (328).

9. The modular chemical synthesis experimental system according to claim 2 or 4, characterized in that: The experimental module (300) further includes a liquid sample adding module (330); The liquid sample adding module (330) contains a liquid sample, and the moving module (400) is used to drive the liquid sample in the liquid sample adding module (330) to move into the reaction kettle (312).

10. The modular chemical synthesis experimental system according to claim 9, characterized in that: The liquid sample adding module (330) comprises a liquid pump assembly; The pump liquid assembly comprises a liquid sample adding base (331), a plunger pump (332), a buffer bottle and a switching valve (333); The liquid sample loading base (331) comprises an upper support and a lower support which are connected to each other, the lower support is detachably connected to the integrated base (100), and a plurality of reagent bottles (339) are placed on the lower support; The plunger pump (332) and the switching valve (333) are both installed on the upper support; The reaction kettle (312) and the plurality of reagent bottles (339) are arranged in parallel and are connected to the switching valve (333); The plunger pump (332) is connected to the switching valve (333) pipeline, and the buffer bottle is arranged on the pipeline between the plunger pump (332) and the switching valve (333). The switching valve (333) is used to control the connection and disconnection between the reactor (312) and the buffer bottle, and control the connection and disconnection between the plurality of reagent bottles (339) and the buffer bottle; The plunger pump (332) is configured to be able to suck the liquid in the plurality of reagent bottles (339) into the cache bottle, and to be able to pump the liquid in the cache bottle into the reaction kettle (312).

11. The modular chemical synthesis experimental system according to claim 10, characterized in that: The liquid loading module (330) further comprises a liquid transfer assembly; The liquid transfer assembly comprises a liquid transfer base (334), a liquid transfer gun recovery box (335), a liquid transfer gun hanger (336) and a liquid transfer gun box (337); The pipetting base (334) is detachably connected to the integrated base (100), and the pipetting gun recovery box (335), the pipetting gun hanger (336) and the pipetting gun box (337) are all arranged on the pipetting base (334); The pipette gun box (337) stores a pipette gun component, and the moving module (400) is configured to be able to grab the pipette gun component in the pipette gun box (337) and drive the pipette gun component to move, so that the pipette gun component absorbs the liquid sample in the reagent bottle (339) and drips it into the reaction kettle (312); The pipette gun rack (336) is used to hang the pipette gun component; The pipette recovery box (335) is used to recover the pipette components after use.

12. The modular chemical synthesis experimental system according to claim 1, characterized in that: The electrical module (200) comprises at least one of a power module (210), a communication module (220), a vacuum module, a water separation module (230), and a gas separation module (240).

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