Nucleic acid extraction device for nucleic acid extractor

Abstract

The invention discloses a nucleic acid extraction device for a nucleic acid extractor, and relates to the field of nucleic acid extraction devices. The nucleic acid extraction device for the nucleic acid extraction instrument comprises a nucleic acid extraction instrument body, a supporting plate is arranged in the nucleic acid extraction instrument body, a door plate is installed on the front face of the nucleic acid extraction instrument body, the supporting plate is arranged above a shaking plate, the nucleic acid extraction instrument body is movably provided with a movable box, and the shaking plate is movably arranged in the movable box. A shaking block is rotatably arranged in the nucleic acid extraction instrument main body, a closing plate is rotatably arranged in the door plate, the closing plate is arranged above the supporting plate, fixing plates are arranged on the two sides of the closing plate, and the fixing plates fix the position of the moving plate when the closing plate moves up and down. According to the nucleic acid extraction device for the nucleic acid extractor, the positions of a plurality of groups of reagent bottles on the supporting plate are shaken and mixed by using the rotation of the shaking block, and meanwhile, the positions of the reagent bottles during shaking mixing and moving are fixed by using the sealing plate.

Description

Technical Field

[0001] The invention relates to the technical field of nucleic acid extraction devices, in particular to a nucleic acid extraction device for a nucleic acid extraction instrument. Background Art

[0002] Nucleic acid extractors are mostly used for extracting viral nucleic acids. Nucleic acid extraction devices are usually used in conjunction with nucleic acid extractors to increase the rapid, efficient and automated extraction of nucleic acids. They can handle various types of samples, including blood, tissue, swabs, nasopharyngeal secretions, etc. First, the sample to be extracted is added to a reagent bottle, and appropriate pretreatment is performed to mix the nucleic acid with a specific solution, and then the mixture is shaken and placed above the internal support plate of the nucleic acid extractor. The elution adsorption structure is then opened to adsorb and separate the nucleic acid, thereby extracting the nucleic acid.

[0003] The existing nucleic acid extraction device is prone to liquid spillage during manual shaking and reagent bottle position movement during use. At the same time, there are multiple groups of reagent bottles in the nucleic acid extraction, which increases the complexity of manual preparation. The reason for this problem is that during the use of the nucleic acid extractor, the nucleic acid needs to be pretreated, and then the nucleic acid mixture is shaken and mixed, and the mixed nucleic acid reagent bottle is placed above the support plate. In order to improve the efficiency of one-time nucleic acid extraction, the nucleic acid extractor will place multiple groups of nucleic acid reagent bottles on the support plate at one time. At this time, the mixing and shaking of the nucleic acid causes complexity, and the support plate needs to be pulled out from the inside of the nucleic acid extractor during use. After the nucleic acid reagent bottle is placed, the support plate needs to be pushed to send the reagent bottle into the main body of the nucleic acid extractor. If the user uses improper force at this time, the reagent bottle will fall over and the liquid in the reagent bottle will spill. If a cover is set above the reagent bottle, the nucleic acid reagent bottle needs to be extracted by an adsorption extraction device after entering the nucleic acid extractor. At this time, the position of the cover will hinder the extraction process. Therefore, we propose a nucleic acid extraction device for a nucleic acid extractor. Summary of the invention

[0004] 1. Technical issues to be resolved In view of the shortcomings of the prior art, the present invention discloses a nucleic acid extraction device for a nucleic acid extraction instrument to solve the problem raised in the above background technology that the existing nucleic acid extraction device is prone to liquid spillage during manual shaking and movement of reagent bottles during use, and that multiple groups of reagent bottles are provided in the nucleic acid extraction, thereby increasing the complexity of manual preparation.

[0005] (II) Technical solution To achieve the above objectives, the present invention is implemented through the following technical solutions: a nucleic acid extraction device for a nucleic acid extraction instrument, comprising a nucleic acid extraction instrument body, a support plate is arranged inside the nucleic acid extraction instrument body, a door panel is installed on the front of the nucleic acid extraction instrument body, the support plate is arranged above a shaking plate, a movable box is movably arranged on the nucleic acid extraction instrument body, the shaking plate is movably arranged inside the movable box, a shaking block is rotatably arranged inside the nucleic acid extraction instrument body, the shaking block contacts the bottom of the shaking plate through a protruding surface to make the shaking plate shake up and down, a movable plate is fixedly connected to the bottom of the movable box, the movable plate is movably plugged into the door panel, the closing plate is rotatably arranged inside the door panel, the closing plate is arranged above the support plate, the closing plate closes and fixes the reagent bottle shaking outside the support plate, and fixed plates are arranged on both sides of the closing plate, and the fixed plates fix the position of the movable plate when the closing plate moves up and down.

[0006] Preferably, the interior of the nucleic acid extraction instrument body is fixedly connected to an outer frame plate, the interior of the outer frame plate is fixedly connected to a mounting plate, the interior of the mounting plate is fixedly connected to a sliding block, the upper surface of the sliding block is fixedly connected to an inner slide plate, the interior of the mounting plate is rotatably connected to a rolling rod, the inner slide plate is movably arranged on the outside of the rolling rod, the inner slide plate is slidably connected to the interior of the mounting plate, and the inner slide plate is fixedly connected to the lower surface of the movable box.

[0007] Preferably, a telescopic plate is fixedly connected to the interior of the movable box, the telescopic plate is fixedly connected above the shaking plate, an auxiliary spring is fixedly connected to the upper surface of the shaking plate, the top of the auxiliary spring is fixedly connected to the interior of the movable box, a limiting rod is fixedly connected to the interior of the movable box, and the shaking plate is movably sleeved on the outside of the limiting rod.

[0008] Preferably, the lower surface of the shaking plate is fixedly connected to a base plate, the lower surface of the base plate is fixedly connected to an arc block, the side of the mounting plate is fixedly connected to a baffle, a bidirectional motor is installed inside the outer frame plate, the shaking block is fixedly connected to the outer surface of the output end of the bidirectional motor, the shaking block is movably arranged inside the baffle, and the outside of the shaking block is in contact with the outer surface of the arc block.

[0009] Preferably, a glue plate is fixedly connected to the back of the door panel, the outer surface of the glue plate is abutted against the front of the nucleic acid extractor body, a connecting piece is fixedly connected to the end of the movable plate, the connecting piece is movably plugged into the inside of the glue plate, the connecting piece is movably plugged into the inside of the door panel, plug-ins are fixedly connected to both sides of the door panel, socket connectors are fixedly connected to both sides of the nucleic acid extractor body, the plug-in connector is movably plugged into the inside of the socket, a fixed block is fixedly connected to the outside of the door panel away from the plug-in connector, fixing pieces are installed on both sides of the nucleic acid extractor body, and the fixing pieces are movably plugged into the inside of the fixed block.

[0010] Preferably, the door panel is fixedly connected to a mounting frame inside, a rotating plate is rotatably arranged inside the mounting frame, rotating blocks are rotatably connected to both sides of the rotating plate, the rotating blocks are movably arranged inside the mounting frame, electric telescopic rods are installed on both sides of the mounting frame, the electric telescopic rods are installed inside the door panel, the top of the electric telescopic rod is fixedly connected to a movable block, the upper surface of the movable block is fixedly connected to a rotating motor, the rotating block is fixedly connected to the outer surface of the output end of the rotating motor, the fixed plate is fixedly connected to the lower surface of the movable block, and the fixed plate is movably inserted into the inside of the connecting piece.

[0011] Preferably, the outside of the rotating plate is fixedly connected to the center plate, the closing plate is movably sleeved on the outside of the center plate, the inner bottom of the closing plate is fixedly connected to a connecting block, the connecting block is movably inserted into the inside of the center plate, the side of the connecting block is fixedly connected to a pushing block, and the pushing block is movably arranged above the center plate.

[0012] Preferably, the top end of the center plate is fixedly connected to a connecting rod, the external movably sleeved with a functional spring, the functional spring is fixedly connected to the upper surface of the push block, the top end of the connecting rod is fixedly connected to a top plate, the top end of the functional spring is fixedly connected to the lower surface of the top plate, and the closing plate is movably sleeved on the outside of the top plate.

[0013] Preferably, a water inlet box is fixedly connected to the interior of the door panel, the water inlet box is arranged above the installation frame, the interior of the water inlet box is connected to the interior of the installation frame, and a water receiving box is movably provided inside the door panel, the water receiving box is connected to the interior of the installation frame, and the water receiving box is arranged below the installation frame.

[0014] The present invention discloses a nucleic acid extraction device for a nucleic acid extraction instrument, which has the following beneficial effects:

[0015] 1. The nucleic acid extraction device used in the nucleic acid extraction instrument fixes and seals the reagent bottles above the support plate by moving the sealing plate, and then starts the bidirectional motor to drive the shaking block to rotate and make the shaking plate squeeze the auxiliary spring. When the convex surface of the shaking block leaves the outside of the arc block, the auxiliary spring will lose the squeezing force and generate tension, so that the shaking plate drives the support plate to shake, thereby shaking and mixing the liquid inside all the reagent bottles above the support plate. By rotating the shaking block to shake and mix the positions of multiple groups of reagent bottles on the support plate, the complexity of manually shaking the reagent solution is reduced. At the same time, the sealing plate is used to fix the position of the reagent bottle in the shaking and mixing and moving state. The sealing plate will also move up and down with the shaking of the reagent bottle using the tension of the functional spring, which increases the safety and sealing of the reagent solution during mixing.

[0016] 2. The nucleic acid extraction instrument uses a nucleic acid extraction device. After the reagent bottle is shaken and mixed, the electric telescopic rod is turned on to drive the closing plate to leave the top position of the reagent bottle. At this time, the movable block will also drive the fixed plate to move away from the inside of the connecting piece, and then the position of the door panel is moved until the closing plate moves out of the inside of the nucleic acid extraction instrument body. Then, the rotating motor is turned on to drive the rotating plate to rotate until the rotating plate drives the closing plate to rotate into the inside of the installation frame. Finally, the door panel is moved back to the front of the nucleic acid extraction instrument body. After shaking and mixing, the closing plate is removed from the top of the reagent bottle and retracted into the inside of the installation frame, so that the use of the closing plate will not affect the subsequent nucleic acid extraction of the nucleic acid solution in the reagent bottle.

[0017] 3. The nucleic acid extraction device used in the nucleic acid extraction instrument retracts the closing plate into the interior of the installation frame, and then pours cleaning water into the opening of the water inlet box. At this time, the cleaning liquid will flow from the opening position of the inclined surface at the bottom of the water inlet box to the side of the closing plate that closes the reagent bottle port, thereby cleaning the side of the closing plate that closes the reagent bottle port. Subsequently, after the cleaning liquid has rinsed the side of the closing plate that closes the reagent bottle port, the cleaning liquid will flow to the inside of the water receiving box along the opening at the bottom of the installation frame. After the cleaning is completed, the water receiving box is taken out from the inside of the door panel and poured out, so that after the closing plate closes the reagent bottle port, the closed surface of the closing plate is cleaned, and this process will not affect the normal use of the main body of the nucleic acid extraction instrument. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 It is a schematic diagram of the overall structure of the present invention; Figure 2 This is a schematic diagram of the interior of the main body of the nucleic acid extraction instrument of the present invention; Figure 3 It is the external schematic diagram of the outer frame plate of the present invention; Figure 4 This is an exploded view of the interior of the outer frame plate of the present invention; Figure 5This is an external exploded view of the swaying plate of the present invention; Figure 6 This is an exploded view of the interior of the activity box of the present invention; Figure 7 This is a schematic diagram of the back side of the door panel of the present invention; Figure 8 This is a cross-sectional view of the interior of the door panel of the present invention; Fig. 9 This is a schematic diagram of the interior of the installation frame of the present invention; Fig.10 This is an exploded view of the side of the door panel of the present invention; Fig.11 This is an external exploded view of the center plate of the present invention; Fig.12 This is an internal exploded view of the door panel of the present invention.

[0019] In the figure: 1. Nucleic acid extraction instrument body; 101. Door panel; 102. Support plate; 2. Shaking plate; 201. Inner slide plate; 202. Movable box; 203. Shaking block; 204. Connector; 205. Mounting plate; 206. Rolling rod; 207. Moving plate; 208. Sliding block; 209. Limiting rod; 210. Telescopic plate; 211. Arc block; 212. Bottom plate; 213. Outer frame plate; 214. Bidirectional motor; 215. Auxiliary spring; 216. Socket; 2 17. Connector; 218. Baffle; 3. Closing plate; 301. Mounting frame; 302. Rotating motor; 303. Electric telescopic rod; 304. Rotating plate; 305. Fixed plate; 306. Movable block; 307. Top plate; 308. Center plate; 309. Push block; 310. Connecting block; 311. Connecting rod; 312. Rubber plate; 313. Fixing piece; 314. Rotating block; 315. Fixed block; 316. Functional spring; 4. Water inlet tank; 401. Water receiving tank. DETAILED DESCRIPTION

[0020] The embodiment of the present invention discloses a nucleic acid extraction device for a nucleic acid extraction instrument, such as Figure 1-12 As shown, in order to make the purpose, technical solution and advantages of the embodiments of the present invention clearer, the technical solution in the embodiments of the present invention will be clearly and completely described below in combination with the drawings in the present invention and by way of example.

[0021] like Figure 1-12The nucleic acid extraction device for a nucleic acid extraction instrument shown in the figure comprises a nucleic acid extraction instrument body 1, a support plate 102 is arranged inside the nucleic acid extraction instrument body 1, a door panel 101 is installed on the front of the nucleic acid extraction instrument body 1, the support plate 102 is arranged above a shaking plate 2, a movable box 202 is movably arranged on the nucleic acid extraction instrument body 1, the shaking plate 2 is movably arranged inside the movable box 202, a shaking block 203 is rotatably arranged inside the nucleic acid extraction instrument body 1, the shaking block 203 contacts the bottom of the shaking plate 2 through the protruding surface to make the shaking plate 2 shake up and down, a movable plate 207 is fixedly connected to the bottom of the movable box 202, the movable plate 207 is movably plugged into the inside of the door panel 101, a closing plate 3 is rotatably arranged inside the door panel 101, the closing plate 3 is arranged above the support plate 102, the closing plate 3 closes and fixes the reagent bottle shaking outside the support plate 102, and fixed plates 305 are arranged on both sides of the closing plate 3, and the fixed plates 305 fix the position of the movable plate 207 when the closing plate 3 moves up and down.

[0022] The interior of the nucleic acid extraction instrument body 1 is fixedly connected to an outer frame plate 213, the interior of the outer frame plate 213 is fixedly connected to a mounting plate 205, the interior of the mounting plate 205 is fixedly connected to a sliding block 208, the upper surface of the sliding block 208 is fixedly connected to an inner slide plate 201, the interior of the mounting plate 205 is rotatably connected to a rolling rod 206, the inner slide plate 201 is movably arranged on the outside of the rolling rod 206, the inner slide plate 201 is slidably connected to the interior of the mounting plate 205, and the inner slide plate 201 is fixedly connected to the lower surface of the movable box 202.

[0023] The movable box 202 is internally fixedly connected with a telescopic plate 210, the telescopic plate 210 is fixedly connected above the shaking plate 2, the upper surface of the shaking plate 2 is fixedly connected with an auxiliary spring 215, the top end of the auxiliary spring 215 is fixedly connected to the inside of the movable box 202, the movable box 202 is internally fixedly connected with a limiting rod 209, and the shaking plate 2 is movably sleeved on the outside of the limiting rod 209.

[0024] The lower surface of the shaking plate 2 is fixedly connected to the base plate 212, the lower surface of the base plate 212 is fixedly connected to the arc block 211, the side of the mounting plate 205 is fixedly connected to the baffle 218, a bidirectional motor 214 is installed inside the outer frame plate 213, the shaking block 203 is fixedly connected to the outer surface of the output end of the bidirectional motor 214, the shaking block 203 is movably arranged inside the baffle 218, and the outside of the shaking block 203 is in contact with the outer surface of the arc block 211.

[0025] A gelatin plate 312 is fixedly connected to the back of the door panel 101, and the outer surface of the gelatin plate 312 is against the front of the nucleic acid extractor body 1. A connector 204 is fixedly connected to the end of the movable plate 207, and the connector 204 is movably inserted into the inside of the gelatin plate 312. The connector 204 is movably inserted into the inside of the door panel 101. Connectors 217 are fixedly connected to both sides of the door panel 101, and sockets 216 are fixedly connected to both sides of the nucleic acid extractor body 1, and the connector 217 is movably inserted into the inside of the socket 216. A fixed block 315 is fixedly connected to the outside of the door panel 101 away from the connector 217. Fixing parts 313 are installed on both sides of the nucleic acid extractor body 1, and the fixing parts 313 are movably inserted into the inside of the fixed block 315.

[0026] The door panel 101 is fixedly connected to the inside of the installation frame 301, and a rotating plate 304 is rotatably arranged inside the installation frame 301. Rotating blocks 314 are rotatably connected to both sides of the rotating plate 304. The rotating blocks 314 are movably arranged inside the installation frame 301. Electric telescopic rods 303 are installed on both sides of the installation frame 301. The electric telescopic rods 303 are installed inside the door panel 101. The top of the electric telescopic rod 303 is fixedly connected to a movable block 306. The upper surface of the movable block 306 is fixedly connected to a rotating motor 302. The rotating block 314 is fixedly connected to the outer surface of the output end of the rotating motor 302. The fixed plate 305 is fixedly connected to the lower surface of the movable block 306. The fixed plate 305 is movably inserted into the inside of the connecting piece 204.

[0027] The outside of the rotating plate 304 is fixedly connected to the center plate 308, the closing plate 3 is movably sleeved on the outside of the center plate 308, the inner bottom of the closing plate 3 is fixedly connected to the connecting block 310, the connecting block 310 is movably inserted into the inside of the center plate 308, and the side of the connecting block 310 is fixedly connected to the pushing block 309, which is movably set above the center plate 308.

[0028] The top end of the center plate 308 is fixedly connected to a connecting rod 311, and the outside of the connecting rod 311 is movably sleeved with a functional spring 316, which is fixedly connected to the upper surface of the push block 309. The top end of the connecting rod 311 is fixedly connected to a top plate 307, and the top end of the functional spring 316 is fixedly connected to the lower surface of the top plate 307. The closing plate 3 is movably sleeved on the outside of the top plate 307.

[0029] The door panel 101 has a water inlet box 4 fixedly connected to the inside thereof, which is disposed above the mounting frame 301. The inside of the water inlet box 4 is connected to the inside of the mounting frame 301. The door panel 101 has a water receiving box 401 movably disposed inside thereof, which is connected to the inside of the mounting frame 301. The water receiving box 401 is disposed below the mounting frame 301.

[0030] The nucleic acid is extracted by adding the sample to be extracted into a reagent bottle and performing appropriate pretreatment so that the nucleic acid is mixed with a specific solution, and then mixing and shaking the mixture. The mixed and shaken reagent bottle is placed above the support plate 102 inside the main body 1 of the nucleic acid extractor, and then the elution adsorption structure is opened to adsorb and separate the nucleic acid, thereby extracting the nucleic acid.

[0031] By moving the position of the fixing member 313, the fixing member 313 is moved away from the inside of the fixing block 315, and then the door panel 101 is pulled to drive the connecting member 204 and the moving plate 207 to move. At this time, the fixing plate 305 is inserted into the inside of the connecting member 204, and the moving plate 207 will slide inside the mounting plate 205. The moving plate 207 will drive the sliding block 208 to slide inside the mounting plate 205 during the sliding process, and the sliding block 208 will drive the inner slide plate 201 to move. At this time, the inner slide plate 201 will slide inside the mounting plate 205, and the inner slide plate 201 will move outside the rolling rod 206 during the sliding process. 06 reduces the friction of the movement of the inner slide 201. At this time, the inner slide 201 will drive the movable box 202 and the support plate 102 to move out of the front position of the nucleic acid extraction instrument body 1. At this time, the connector 217 will also slide inside the socket 216. At this time, the rotating motor 302 is turned on to drive the rotating block 314 and the rotating plate 304 to rotate. During the rotation process, the rotating plate 304 will drive the closing plate 3 to rotate out of the installation frame 301, and the electric telescopic rod 303 is turned on to move upward, so that the electric telescopic rod 303 pushes the movable block 306 and the closing plate 3 to move upward. At this time, the movable block 306 will drive the fixed plate 305 to leave The reagent bottle is then placed on the support plate 102. A convex block is provided on the support plate 102, corresponding to the concave surface at the bottom of the reagent bottle. The reagent bottle is placed on the convex block outside the support plate 102. The electric telescopic rod 303 is then turned on to drive the movable block 306 and the closing plate 3 to move downward, so that the closing plate 3 moves to a position where the bottom of the reagent bottle is abutted. The rubber plate at the bottom of the closing plate 3 can shrink under compression, thereby closing the port position of the reagent bottle under extrusion, and the movable block 306 drives the fixed plate 305 to move while moving downward. Plug it into the inside of the connector 204, and then push the door panel 101 toward the inside of the nucleic acid extractor body 1, so that the door panel 101 drives the movable plate 207 and the support plate 102 to move, and then the support plate 102 will move to the inside of the nucleic acid extractor body 1 until the outer surface of the gelatin plate 312 is against the front position of the nucleic acid extractor body 1, and then the fixing piece 313 can be movably plugged into the inside of the fixing block 315, and then the closing plate 3 is rotated and moved upward, and then the reagent bottle is placed above the support plate 102, and then the closing plate 3 is moved downward to fix and close the reagent bottle above the support plate 102.

[0032] The reagent bottle above the support plate 102 is fixedly closed by moving the closing plate 3, and then the support plate 102 and the reagent bottle are sent to the interior of the nucleic acid extraction instrument main body 1, so as to increase the stability and safety of the reagent bottle movement and reduce the movement and shaking of the reagent bottle. Then, the bidirectional motor 214 is turned on to drive the shaking block 203 to rotate. The shaking block 203 will move the protruding position to the arc surface of the arc block 211 during a small rotation. At this time, the protruding position of the shaking block 203 will push the arc block 211 upward. At this time, the arc block 211 will push the bottom plate 212 and the shaking plate 2 upward, so that the shaking plate 2 slides inside the movable box 202, and the telescopic plate 210 will also shrink due to the squeezing force. At this time, the shaking plate 2 will squeeze the auxiliary spring 215. When the protruding surface of the shaking block 203 leaves the outside of the arc block 211 At this time, the auxiliary spring 215 will lose the extrusion force and generate tension, and push the shaking plate 2 to move downward, so that the shaking plate 2 drives the support plate 102 to shake, thereby shaking and mixing the liquid inside all the reagent bottles above the support plate 102, and at this time the closing plate 3 will also move up and down due to the shaking of the reagent bottles, and the closing plate 3 will drive the functional spring 316 to contract and generate tension, so that the closing plate 3 can move with the up and down shaking of the reagent bottles, thereby increasing the sealing effect of the closing plate 3, and by using the shaking block 203 to rotate the positions of multiple groups of reagent bottles on the support plate 102 to shake and mix, thereby reducing the complexity of manually shaking the reagent solution, and at the same time using the closing plate 3 to fix the positions of the reagent bottles in the shaking and mixing and moving state, thereby increasing the safety and sealing of the reagent solution during mixing.

[0033] After the reagent bottle is shaken and mixed, the electric telescopic rod 303 is turned on to drive the movable block 306, the rotating plate 304 and the closing plate 3 to move, so that the closing plate 3 leaves the top position of the reagent bottle. At this time, the movable block 306 will also drive the fixed plate 305 to move away from the inside of the connecting piece 204. After the fixed plate 305 leaves the inside of the connecting piece 204, the connecting piece 204 and the movable plate 207 will not move with the door panel 101. Then, the position of the door panel 101 is moved so that the door panel 101 drives the connector 217 to slide inside the socket 216 until the position of the closing plate 3 moves out of the inside of the nucleic acid extraction instrument body 1. , and then turn on the rotating motor 302 to drive the rotating plate 304 to rotate until the rotating plate 304 drives the closing plate 3 to rotate into the interior of the installation frame 301, and finally move the door panel 101 back to the front of the nucleic acid extractor body 1, and then turn on the electric telescopic rod 303 to drive the movable block 306 and the fixed plate 305 to move, so that the fixed plate 305 can be movably inserted into the interior of the connecting piece 204, and the closing plate 3 is removed from the top of the reagent bottle after shaking and mixing, and the closing plate 3 is retracted into the interior of the installation frame 301, so that the use of the closing plate 3 will not affect the subsequent nucleic acid extraction work of the nucleic acid solution inside the reagent bottle.

[0034] After the closing plate 3 is retracted into the interior of the installation frame 301, the cleaning water is poured into the opening of the water inlet box 4. At this time, the cleaning liquid will flow from the opening position of the bottom inclined surface of the water inlet box 4 to the side of the closing plate 3 that closes the reagent bottle port, thereby cleaning the side of the closing plate 3 that closes the reagent bottle port. After the cleaning liquid rinses the side of the closing plate 3 that closes the reagent bottle port, the cleaning liquid will flow to the inside of the water receiving box 401 along with the opening at the bottom of the installation frame 301. After the cleaning is completed, the water receiving box 401 is taken out from the inside of the door panel 101 and poured out, so that after the closing plate 3 closes the reagent bottle port, the closed surface of the closing plate 3 is cleaned, and the normal use of the nucleic acid extraction instrument body 1 will not be affected in this process. The above shows and describes the basic principles and main features of the present invention and the advantages of the present invention. The technicians in this industry should understand that the present invention is not limited to the above embodiments. The above embodiments and the description only illustrate the principles of the present invention. Without departing from the spirit and scope of the present invention, the present invention will also have various changes and improvements, and these changes and improvements all fall within the scope of the present invention to be protected. The protection scope of the present invention is defined by the following claims and their equivalents.

Claims

1. A nucleic acid extraction device for a nucleic acid extraction instrument, comprising a nucleic acid extraction instrument body (1), wherein a support plate (102) is arranged inside the nucleic acid extraction instrument body (1), and a door plate (101) is installed on the front of the nucleic acid extraction instrument body (1), characterized in that: The support plate (102) is provided with a shaking mechanism on the outside, and the door plate (101) is provided with a closing mechanism on the inside; The shaking mechanism comprises a shaking plate (2), the support plate (102) being arranged above the shaking plate (2), the nucleic acid extractor body (1) being movably provided with a movable box (202), the shaking plate (2) being movably provided inside the movable box (202), a shaking block (203) being rotatably provided inside the nucleic acid extractor body (1), the shaking block (203) being in contact with the bottom of the shaking plate (2) via a protruding surface so as to cause the shaking plate (2) to shake up and down, a movable plate (207) being fixedly connected to the bottom of the movable box (202), and the movable plate (207) being movably plugged into the interior of the door panel (101); The sealing mechanism comprises a sealing plate (3), wherein the sealing plate (3) is rotatably arranged inside the door plate (101), the sealing plate (3) is arranged above the support plate (102), the sealing plate (3) seals and fixes the reagent bottle shaking outside the support plate (102), and fixing plates (305) are arranged on both sides of the sealing plate (3), and the fixing plates (305) fix the position of the movable plate (207) when the sealing plate (3) moves up and down.

2. The nucleic acid extraction device for a nucleic acid extraction instrument according to claim 1, characterized in that: The interior of the nucleic acid extraction instrument body (1) is fixedly connected to an outer frame plate (213), the interior of the outer frame plate (213) is fixedly connected to a mounting plate (205), the interior of the mounting plate (205) is fixedly connected to a sliding block (208), the upper surface of the sliding block (208) is fixedly connected to an inner slide plate (201), the interior of the mounting plate (205) is rotatably connected to a rolling rod (206), the inner slide plate (201) is movably arranged outside the rolling rod (206), the inner slide plate (201) is slidably connected to the interior of the mounting plate (205), and the inner slide plate (201) is fixedly connected to the lower surface of the movable box (202).

3. The nucleic acid extraction device for a nucleic acid extraction instrument according to claim 1, characterized in that: The movable box (202) is fixedly connected to a telescopic plate (210) inside, the telescopic plate (210) is fixedly connected above the shaking plate (2), the upper surface of the shaking plate (2) is fixedly connected to an auxiliary spring (215), the top end of the auxiliary spring (215) is fixedly connected to the inside of the movable box (202), the inside of the movable box (202) is fixedly connected to a limit rod (209), and the shaking plate (2) is movably sleeved on the outside of the limit rod (209).

4. The nucleic acid extraction device for a nucleic acid extraction instrument according to claim 2, characterized in that: The lower surface of the shaking plate (2) is fixedly connected to a bottom plate (212), the lower surface of the bottom plate (212) is fixedly connected to an arc block (211), the side surface of the mounting plate (205) is fixedly connected to a baffle (218), a bidirectional motor (214) is installed inside the outer frame plate (213), the shaking block (203) is fixedly connected to the outer surface of the output end of the bidirectional motor (214), the shaking block (203) is movably arranged inside the baffle (218), and the outside of the shaking block (203) is in contact with the outer surface of the arc block (211).

5. The nucleic acid extraction device for a nucleic acid extraction instrument according to claim 1, characterized in that: The back of the door panel (101) is fixedly connected to a glue plate (312), the outer surface of the glue plate (312) abuts against the front of the nucleic acid extraction instrument body (1), the end of the movable plate (207) is fixedly connected to a connecting piece (204), the connecting piece (204) is movably plugged into the inside of the glue plate (312), the connecting piece (204) is movably plugged into the inside of the door panel (101), both sides of the door panel (101) are fixedly connected to plug-in pieces (217), both sides of the nucleic acid extraction instrument body (1) are fixedly connected to socket pieces (216), the plug-in pieces (217) are movably plugged into the inside of the socket pieces (216), a fixed block (315) is fixedly connected to the outside of the door panel (101) at a position away from the plug-in pieces (217), and fixing pieces (313) are installed on both sides of the nucleic acid extraction instrument body (1), the fixing pieces (313) are movably plugged into the inside of the fixing blocks (315).

6. The nucleic acid extraction device for a nucleic acid extraction instrument according to claim 1, characterized in that: The door panel (101) is fixedly connected to a mounting frame (301) inside, a rotating plate (304) is rotatably arranged inside the mounting frame (301), rotating blocks (314) are rotatably connected to both sides of the rotating plate (304), the rotating blocks (314) are movably arranged inside the mounting frame (301), electric telescopic rods (303) are installed on both sides of the mounting frame (301), the electric telescopic rods (303) are installed inside the door panel (101), a movable block (306) is fixedly connected to the top of the electric telescopic rod (303), a rotating motor (302) is fixedly connected to the upper surface of the movable block (306), the rotating block (314) is fixedly connected to the outer surface of the output end of the rotating motor (302), the fixed plate (305) is fixedly connected to the lower surface of the movable block (306), and the fixed plate (305) is movably plugged into the inside of the connecting piece (204).

7. The nucleic acid extraction device for a nucleic acid extraction instrument according to claim 6, characterized in that: The outside of the rotating plate (304) is fixedly connected to a center plate (308), the closing plate (3) is movably sleeved on the outside of the center plate (308), the inner bottom of the closing plate (3) is fixedly connected to a connecting block (310), the connecting block (310) is movably inserted into the inside of the center plate (308), and the side of the connecting block (310) is fixedly connected to a pushing block (309), and the pushing block (309) is movably arranged above the center plate (308).

8. The nucleic acid extraction device for a nucleic acid extraction instrument according to claim 7, characterized in that: The top end of the center plate (308) is fixedly connected to a connecting rod (311), the outside of the connecting rod (311) is movably sleeved with a functional spring (316), the functional spring (316) is fixedly connected to the upper surface of the push block (309), the top end of the connecting rod (311) is fixedly connected to a top plate (307), the top end of the functional spring (316) is fixedly connected to the lower surface of the top plate (307), and the closing plate (3) is movably sleeved on the outside of the top plate (307).

9. The nucleic acid extraction device for a nucleic acid extraction instrument according to claim 1, characterized in that: A water inlet box (4) is fixedly connected to the interior of the door panel (101); the water inlet box (4) is arranged above the installation frame (301); the interior of the water inlet box (4) is connected to the interior of the installation frame (301); a water receiving box (401) is movably arranged inside the door panel (101); the water receiving box (401) is connected to the interior of the installation frame (301); and the water receiving box (401) is arranged below the installation frame (301).

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