A mixing device for pharmaceutical production

Abstract

The present invention discloses a mixing device for pharmaceutical production, which relates to the technical field of pharmaceutical production. By providing two spiral mixing air inlet channels on the circumferential surface of the batch mixing chamber, and arranging the two spiral mixing air inlet channels along the tangential direction of the inner wall of the batch mixing chamber, this structural design can effectively utilize the kinetic energy of the spiral air flow, enabling the drugs to be evenly distributed in the batch mixing chamber during the mixing process, avoiding the problem of uneven drug mixing in traditional mixing devices, and significantly improving the mixing efficiency and mixing quality; the baffle fixing pipe arranged inside the mixing cylinder and the multiple baffles fixed and arranged in a spiral cross on its inner wall can generate turbulent flow during the mixing process, further improving the uniformity of drug mixing. Due to the spiral arrangement of the baffles, this design can also effectively disperse and break drug particles during the mixing process, avoiding the problem of drug particle agglomeration during the mixing process.

Description

Technical Field

[0001] The present invention relates to the technical field of pharmaceutical production, and in particular to a mixing device for pharmaceutical production. Background Art

[0002] In the prior art, problems such as uneven mixing, caking of pharmaceutical particles, and blockage of the air intake channel generally exist in pharmaceutical mixing devices. Especially when dealing with a large quantity of pharmaceuticals, it is difficult for traditional devices to ensure uniform mixing and efficient separation of pharmaceuticals. Traditional mixing devices usually adopt simple stirring or vibration methods, and cannot make full use of the kinetic energy and pressure difference effect of air flow, resulting in an unsatisfactory mixing effect, and it is difficult for the purity and quality of pharmaceuticals to meet the expected standards. In addition, when traditional devices handle different quantities of pharmaceuticals, they lack a flexible adjustment mechanism, which easily causes waste of pharmaceuticals and a reduction in the mixing effect. Summary of the Invention

[0003] To overcome the defects of the above-mentioned prior art, the present invention provides the following technical solution: A mixing device for pharmaceutical production, comprising a mixing cylinder and a batch mixing chamber. There are two spiral mixing air intake channels symmetrically centered on the axis of the batch mixing chamber on the circumferential surface of the batch mixing chamber. The two spiral mixing air intake channels are arranged along the tangential direction of the inner wall of the batch mixing chamber. Feeding barrels are fixedly arranged on both of the two spiral mixing air intake channels. A negative pressure intake pipe is fixedly connected to the bottom of the batch mixing chamber. A baffle fixing pipe is slidably installed on the inner wall of the mixing cylinder. A plurality of baffles arranged in a spiral cross are fixedly installed on the inner wall of the baffle fixing pipe for disturbing the spiral air flow. Two accelerating intake pipes are fixedly connected to the bottom of the mixing cylinder along the tangential direction of the inner wall. The two accelerating intake pipes are fixedly connected to a ventilation circular pipe arranged outside the bottom of the mixing cylinder.

[0004] Preferably, the feeding barrel, the spiral mixing air intake channel and the inside of the batch mixing chamber are communicated with each other, and the bottom surfaces of the inner walls of the feeding barrel and the spiral mixing air intake channel are flush. A second conical guiding cover is fixedly connected to the top of the batch mixing chamber, and a feeding guiding side pipe is fixedly connected to the top of the second conical guiding cover.

[0005] Preferably, a circular ring support is fixedly installed at the top end of the baffle fixing pipe. Two support sliding rods are fixedly installed on the outer surface of the mixing cylinder. The two support sliding rods are slidably matched with the circular ring support. A first conical guiding cover is fixedly installed on the circular ring support, and the first conical guiding cover is communicated with the inside of the baffle fixing pipe.

[0006] Preferably, a moving sliding feed pipe is fixedly and communicatively arranged on the first conical guiding cover. The tops of two supporting sliding rods are fixed with a top supporting frame, wherein the moving sliding feed pipe is slidably matched with the top supporting frame. Two limiting stay pipes are fixedly installed on the top supporting frame. Limiting solenoid valves are installed at the tops of the two limiting stay pipes. Limiting stay pistons are slidably and sealingly installed on the inner walls of the two limiting stay pipes. The two limiting stay pistons are fixedly matched with the first conical guiding cover through two limiting stay rods.

[0007] Preferably, it further includes an aggregate pool. A discharge nozzle is arranged at the bottom of the aggregate pool. A discharge screw is rotatably installed at the bottom of the inner wall of the aggregate pool and in the discharge nozzle. A distribution cover is fixedly and communicatively arranged on the aggregate pool. A distribution chamber is coaxially arranged inside the distribution cover. A gap is left between the circumferential surface of the distribution chamber and the inner wall of the distribution cover. The bottom of the distribution chamber and the bottom of the distribution cover are fixedly and sealingly arranged.

[0008] Preferably, a plurality of tangential feed grooves are formed on the circumferential surface of the distribution chamber along the tangential direction of itself. The inside of the distribution cover communicates with the inside of the distribution chamber through the tangential feed grooves.

[0009] Preferably, a separation gas pipe is fixedly installed coaxially inside the distribution chamber. One end of the separation gas pipe is fixed to the top of the inner wall of the distribution chamber. The other end of the separation gas pipe passes through the aggregate pool and extends to the outside of the aggregate pool. A plurality of ventilation holes are formed at the position of the separation gas pipe coaxial with the distribution chamber.

[0010] Preferably, an air filter element can be installed inside the separation gas pipe. The end of the separation gas pipe away from the distribution chamber is connected to the air inlet of an air pump. An air collecting cover is arranged at the air outlet of the air pump. The air outlet of the air pump blows air into the air collecting cover. The air collecting cover partially blocks the air outlet of the air pump, so that part of the air can enter the air collecting cover.

[0011] Preferably, the air collecting cover and the inside of the ventilation circular pipe are communicatively arranged through an air delivery pipe. By blowing air into the inside of the ventilation circular pipe through the air collecting cover, a spiral air flow is formed inside the mixing cylinder.

[0012] Preferably, a fixed sliding feed pipe is fixedly installed on the top supporting frame. The fixed sliding feed pipe is slidably sleeved on the outer surface of the moving sliding feed pipe. The distribution cover and the inside of the fixed sliding feed pipe are fixedly and communicatively arranged through a feed guiding pipe. A communication valve is serially installed on the feed guiding pipe. The feed guiding pipe and the inside of the second conical guiding cover are fixedly and communicatively arranged through a feed guiding bypass pipe.

[0013] The present invention has the following beneficial effects compared with the prior art: (1) By providing two spiral mixing air inlet channels on the circumferential surface of the batch mixing chamber, and arranging the two spiral mixing air inlet channels along the tangential direction of the inner wall of the batch mixing chamber, this structural design can effectively utilize the kinetic energy of the spiral air flow, enabling the medicine to be evenly distributed in the batch mixing chamber during the mixing process, avoiding the problem of uneven medicine mixing in traditional mixing devices, and significantly improving the mixing efficiency and mixing quality; (2) The baffle fixing pipe arranged inside the mixing cylinder and the multiple baffles fixed and arranged in a spiral cross pattern on its inner wall can generate turbulent flow during the mixing process, further improving the uniformity of medicine mixing. Due to the spiral arrangement of the baffles, this design can also effectively disperse and break up medicine particles during the mixing process, avoiding the problem of medicine particles caking during the mixing process; (3) Through the structural design of arranging an air pump, an air collecting hood, an air venting circular pipe and their interconnections, a stable spiral air flow can be formed inside the mixing cylinder, enhancing the mixing effect of the medicine in the mixing cylinder. At the same time, through the setting of the negative pressure inlet pipe, a negative pressure environment can be formed in the batch mixing chamber, and the pressure difference is used to achieve the inhalation and mixing of the medicine, avoiding the phenomenon of the medicine blocking the air inlet channel during the feeding process, and improving the stability and reliability of the device. Brief Description of the Drawings

[0014] Figure 1 It is a schematic diagram of the overall structure of the present invention.

[0015] Figure 2 It is a schematic diagram of the structure at the air collecting hood of the present invention.

[0016] Figure 3 For the present invention Figure 2 Schematic diagram of the structure at position A.

[0017] Figure 4 It is a schematic diagram of the tangential feed trough structure of the present invention.

[0018] Figure 5 It is a schematic diagram of the batch mixing chamber structure of the present invention.

[0019] Figure 6 It is a schematic diagram of the structure at the fixed-sliding feed pipe of the present invention.

[0020] Figure 7 It is a schematic diagram of the structure at the restricted stop piston of the present invention.

[0021] Figure 8 It is a schematic diagram of the structure at the circular ring support of the present invention.

[0022] Figure 9 It is a schematic diagram of the structure at the baffle of the present invention.

[0023] Figure 10This is a schematic diagram of the mixing cylinder structure of the present invention.

[0024] In the figure: 101 - mixing cylinder; 102 - baffle fixing pipe; 103 - baffle; 104 - accelerating intake pipe; 105 - ventilation circular pipe; 106 - circular support; 107 - first conical guiding cover; 108 - moving and sliding feeding pipe; 109 - supporting sliding rod; 110 - restricting stay rod; 111 - top support frame; 112 - restricting stay pipe; 113 - restricting solenoid valve; 114 - fixed and sliding feeding pipe; 115 - restricting stay piston; 116 - air supply pipe; 117 - air collecting hood; 118 - air pump; 119 - feeding guiding pipe; 120 - connecting valve; 121 - material distributing hood; 122 - material distributing chamber; 123 - separating gas pipe; 124 - aggregate pool; 125 - discharging screw; 126 - feeding guiding side pipe; 127 - second conical guiding cover; 128 - batch mixing chamber; 129 - negative pressure intake pipe; 130 - feeding bucket; 131 - spiral mixing intake channel; 132 - discharging nozzle; 133 - tangential feeding groove. Detailed implementation manners

[0025] The following combines the attached Figures 1-10 drawings and further illustrates the technical solution of the present invention through specific implementation manners.

[0026] The present invention provides a mixing device for pharmaceutical production, including a mixing cylinder 101 and a batch mixing chamber 128. There are two spiral mixing air inlet channels 131 symmetrically centered on the axis of the batch mixing chamber 128 on the circumferential surface of the batch mixing chamber 128. The two spiral mixing air inlet channels 131 are arranged along the tangential direction of the inner wall of the batch mixing chamber 128. Feeding buckets 130 are fixedly arranged on both of the two spiral mixing air inlet channels 131. A negative pressure inlet pipe 129 is fixedly connected to the bottom of the batch mixing chamber 128. A baffle fixing pipe 102 is slidably installed on the inner wall of the mixing cylinder 101. A plurality of baffles 103 arranged in a spiral cross pattern are fixedly installed on the inner wall of the baffle fixing pipe 102 for disturbing the spiral air flow. Two accelerating inlet pipes 104 are fixedly connected to the bottom of the mixing cylinder 101 along the tangential direction of the inner wall. The two accelerating inlet pipes 104 are fixedly connected to an air vent circular pipe 105 arranged outside the bottom of the mixing cylinder 101. The feeding buckets 130, the spiral mixing air inlet channels 131 and the inside of the batch mixing chamber 128 are in communication with each other, and the bottom surfaces of the inner walls of the feeding buckets 130 and the spiral mixing air inlet channels 131 are flush. A second conical guiding cover 127 is fixedly connected to the top of the batch mixing chamber 128. A feeding guiding side pipe 126 is fixedly connected to the top of the second conical guiding cover 127. A circular ring support 106 is fixedly installed at the top end of the baffle fixing pipe 102. Two support sliding rods 109 are fixedly installed on the outer surface of the mixing cylinder 101. The two support sliding rods 109 are slidably engaged with the circular ring support 106. A first conical guiding cover 107 is fixedly installed on the circular ring support 106. The first conical guiding cover 107 is in communication with the inside of the baffle fixing pipe 102. A moving sliding feeding pipe 108 is fixedly connected to the first conical guiding cover 107. The top ends of the two support sliding rods 109 are fixed with a top support frame 111. The moving sliding feeding pipe 108 is slidably engaged with the top support frame 111. Two restricting stay pipes 112 are also fixedly installed on the top support frame 111. Restricting solenoid valves 113 are installed at the tops of the two restricting stay pipes 112. Restricting stay pistons 115 are slidably and sealingly installed on the inner walls of the two restricting stay pipes 112. The two restricting stay pistons 115 are fixedly engaged with the first conical guiding cover 107 through two restricting stay rods 110.

[0027] It further includes an aggregate pool 124. A discharge nozzle 132 is arranged at the bottom of the aggregate pool 124. A discharge screw 125 is rotatably installed at the bottom of the inner wall of the aggregate pool 124 and inside the discharge nozzle 132. A material distribution cover 121 is fixedly and communicatively arranged on the aggregate pool 124. A material distribution chamber 122 is coaxially arranged inside the material distribution cover 121. A gap is left between the circumferential surface of the material distribution chamber 122 and the inner wall of the material distribution cover 121. The bottom of the material distribution chamber 122 and the bottom of the material distribution cover 121 are fixedly and sealingly arranged in cooperation. A plurality of tangential feed grooves 133 are formed on the circumferential surface of the material distribution chamber 122 along its tangent direction. The inside of the material distribution cover 121 communicates with the inside of the material distribution chamber 122 through the tangential feed grooves 133. A separation gas pipe 123 is fixedly installed coaxially inside the material distribution chamber 122. One end of the separation gas pipe 123 is fixed to the top of the inner wall of the material distribution chamber 122, and the other end of the separation gas pipe 123 passes through the aggregate pool 124 and extends to the outside of the aggregate pool 124. A plurality of ventilation holes are formed at the position of the separation gas pipe 123 coaxial with the material distribution chamber 122. An air filter element can be installed inside the separation gas pipe 123. The end of the separation gas pipe 123 away from the material distribution chamber 122 is connected to the air inlet of an air pump 118. An air collection cover 117 is arranged at the exhaust port of the air pump 118. The air pump 118 blows air into the air collection cover 117. The air collection cover 117 partially shields the exhaust port of the air pump 118, so that part of the air can enter the air collection cover 117. The air collection cover 117 and the inside of the ventilation ring pipe 105 are communicatively arranged through an air delivery pipe 116. By blowing air into the ventilation ring pipe 105 through the air collection cover 117, a spiral air flow is formed inside the mixing cylinder 101. A fixed-sliding feeding pipe 114 is fixedly installed on the top support frame 111. The fixed-sliding feeding pipe 114 is slidably sleeved on the outer surface of the moving-sliding feeding pipe 108. The material distribution cover 121 and the inside of the fixed-sliding feeding pipe 114 are fixedly and communicatively arranged through a feeding guide pipe 119. A communication valve 120 is serially installed on the feeding guide pipe 119. The feeding guide pipe 119 and the inside of the second conical guide cover 127 are fixedly and communicatively arranged through a feeding guide bypass pipe 126.

[0028] If there are a large number of mixed drugs, pour the drugs into the corresponding feeding buckets 130 respectively, and then start the air pump 118. The air inlet of the air pump 118 makes the inside of the aggregate pool 124 in a negative pressure environment through the separation gas pipe 123 (since the aggregate pool 124 is internally connected to the material distribution chamber 122 and the separation gas pipe 123 is internally connected to the material distribution chamber 122). It is necessary to block the discharge nozzle 132 in advance. This negative pressure will enter the mixing cylinder 101 (baffle fixing pipe 102) through the material distribution chamber 122, tangential feeding groove 133, material distribution hood 121, feeding guide pipe 119, open communication valve 120, fixed and sliding feeding pipe 114, and moving and sliding feeding pipe 108. And because the exhaust port of the air pump 118 is connected to the air collection hood 117, the air collection hood 117 is connected to the ventilation ring pipe 105 through the air supply pipe 116, and the ventilation ring pipe 105 is connected to the mixing cylinder 101 through the acceleration air inlet pipe 104. At this time, a spiral air flow will be formed in the mixing cylinder 101 under the action of the pressure difference. Since the diameter of the air supply pipe 116 is much smaller than the diameter of the feeding guide pipe 119, most of the air will enter the batch mixing chamber 128 from the negative pressure air inlet pipe 129 (the batch mixing chamber 128, feeding guide side pipe 126, and feeding guide pipe 119 are internally connected). At this time, a negative pressure environment is formed in the batch mixing chamber 128, and the drugs poured into the inside of the feeding bucket 130 will be sucked into the batch mixing chamber 128 under the action of the pressure difference and be mixed spirally in the batch mixing chamber 128. It should be noted that too many drugs cannot be poured into the feeding bucket 130 at one time, otherwise the spiral mixing air inlet channel 131 will be blocked. The mixed drugs will enter the material distribution hood 121 along the second conical guide cover 127, the second conical guide cover 127, and the feeding guide pipe 119 under the action of the pressure difference, and then pass through the tangential feeding groove 133 and enter the material distribution chamber 122 tangentially along the inner wall of the material distribution chamber 122, so as to rotate inside the material distribution chamber 122. During the rotation, the drug powder will lean against the inner wall of the material distribution chamber 122 under the action of the centrifugal force, and the middle part is the separated air. The air will enter the separation gas pipe 123 and then enter the air pump 118.

[0029] If the quantity of the mixed medicine is small, it is necessary to block the feeding bucket 130 and the negative pressure intake pipe 129 first. Then open the limiting solenoid valve 113 to make the inside of the limiting stay pipe 112 unobstructed. Since the ventilation ring pipe 105 supplies gas to the inside of the mixing cylinder 101, the pressure inside the mixing cylinder 101 increases. At this time, under the action of the pressure, the gas will push the baffle fixing pipe 102 to slide upward along the inner wall of the mixing cylinder 101. When the baffle fixing pipe 102 slides to a certain height, the user manually lifts the baffle fixing pipe 102 out of the mixing cylinder 101. At this time, close the limiting solenoid valve 113. After the limiting solenoid valve 113 closes, the inside of the limiting stay pipe 112 is in a closed state. At this time, under the action of the pressure difference, the limiting stay piston 115 cannot slide in the limiting stay pipe 112. Therefore, under the limitation of the limiting stay rod 110, the limiting stay pipe 112 will be fixed at a certain height position. At this time, first stop the air pump 118. The user pours the medicine to be mixed into the mixing cylinder 101 at one time, and then opens the limiting solenoid valve 113. Under the action of gravity, the baffle fixing pipe 102 falls back into the mixing cylinder 101 again. After the baffle fixing pipe 102 completely falls into the mixing cylinder 101, close the limiting solenoid valve 113. At this time, since the feeding bucket 130 and the negative pressure intake pipe 129 are in a blocked state, all the air will enter the mixing cylinder 101 from the air collecting cover 117, the air delivery pipe 116, the ventilation ring pipe 105, and the acceleration intake pipe 104. Since the diameter of the acceleration intake pipe 104 is small, it will be injected into the mixing cylinder 101 at a high-speed airflow under the action of the pressure difference. The high-speed airflow will rotate in the mixing cylinder 101, and a turbulent flow will be formed under the shielding of the baffle 103 provided on the baffle fixing pipe 102, thereby increasing the uniformity of the medicine mixing. Then the mixed medicine powder will enter the material distribution cover 121 through the first conical guiding cover 107, the moving sliding feeding pipe 108, the fixed sliding feeding pipe 114, and the feeding guiding pipe 119, so as to separate the air and the medicine. The separated medicine will fall into the aggregate pool 124. When it needs to be discharged, open the discharging nozzle 132 in the blocked state, and then use the motor to drive the discharging screw 125 to rotate. The discharging screw 125 rotates to discharge the medicine inside the aggregate pool 124.

Claims

1. A mixing device for pharmaceutical production, characterized in that: It includes a mixing cylinder (101) and a batch mixing chamber (128). There are two spiral mixing air intake channels (131) on the circumferential surface of the batch mixing chamber (128) that are centrosymmetric about the axis center of the batch mixing chamber (128). The two spiral mixing air intake channels (131) are arranged along the tangential direction of the inner wall of the batch mixing chamber (128). Feeding buckets (130) are fixedly arranged on both of the two spiral mixing air intake channels (131). A negative pressure intake pipe (129) is fixedly connected to the bottom of the batch mixing chamber (128); Among them, a baffle fixing pipe (102) is slidably installed on the inner wall of the mixing cylinder (101). A plurality of baffles (103) arranged in a spiral cross pattern are fixedly installed on the inner wall of the baffle fixing pipe (102) for disturbing the spiral air flow. Two accelerating intake pipes (104) are fixedly connected to the bottom of the mixing cylinder (101) along the tangential direction of the inner wall. The two accelerating intake pipes (104) are fixedly connected to an air ventilation ring pipe (105) arranged outside the bottom of the mixing cylinder (101); It further includes an aggregate pool (124). A discharge nozzle (132) is arranged at the bottom of the aggregate pool (124). A discharge screw (125) is rotatably installed at the bottom of the inner wall of the aggregate pool (124) and inside the discharge nozzle (132). A material distribution hood (121) is fixedly connected to the aggregate pool (124). A material distribution chamber (122) is coaxially arranged inside the material distribution hood (121). There is a gap between the circumferential surface of the material distribution chamber (122) and the inner wall of the material distribution hood (121). The bottom of the material distribution chamber (122) and the bottom of the material distribution hood (121) are fixedly fitted in a sealed arrangement; A separation gas pipe (123) is fixedly installed coaxially inside the material distribution chamber (122). An air filter element can be installed inside the separation gas pipe (123). One end of the separation gas pipe (123) away from the material distribution chamber (122) is connected to the air inlet of an air pump (118). An air collecting hood (117) is arranged at the exhaust port of the air pump (118). The exhaust port of the air pump (118) blows air into the air collecting hood (117); The air collecting hood (117) and the inside of the air ventilation ring pipe (105) are connected and arranged through an air delivery pipe (116). By blowing air into the inside of the air ventilation ring pipe (105) through the air collecting hood (117), a spiral air flow is formed inside the mixing cylinder (101); The feeding bucket (130), the spiral mixing air inlet channel (131) and the batch mixing chamber (128) are internally connected. Moreover, the bottom surfaces of the inner walls of the feeding bucket (130) and the spiral mixing air inlet channel (131) are flush. A second conical guiding cover (127) is fixedly connected to the top of the batch mixing chamber (128), and a feeding guiding side pipe (126) is fixedly connected to the top of the second conical guiding cover (127); A circular ring support (106) is fixedly installed at the top end of the baffle fixing pipe (102). Two support sliding rods (109) are fixedly installed on the outer surface of the mixing cylinder (101). The two support sliding rods (109) are slidably engaged with the circular ring support (106). A first conical guiding cover (107) is fixedly installed on the circular ring support (106), and the first conical guiding cover (107) is internally connected to the baffle fixing pipe (102); A moving and sliding feeding pipe (108) is fixedly connected to the first conical guiding cover (107). The top ends of the two support sliding rods (109) are fixed with a top support frame (111). Among them, the moving and sliding feeding pipe (108) is slidably engaged with the top support frame (111). Two limiting stay pipes (112) are also fixedly installed on the top support frame (111). Limiting solenoid valves (113) are installed at the tops of the two limiting stay pipes (112). Limiting stay pistons (115) are slidably and sealingly installed on the inner walls of the two limiting stay pipes (112). The two limiting stay pistons (115) are fixedly cooperated with the first conical guiding cover (107) through two limiting stay rods (110).

2. The mixing device for pharmaceutical production according to claim 1, wherein: A plurality of tangential feeding grooves (133) are formed on the circumferential surface of the material distribution chamber (122) along its tangent direction. Among them, the inside of the material distribution cover (121) is connected to the inside of the material distribution chamber (122) through the tangential feeding grooves (133).

3. The mixing device for pharmaceutical production according to claim 2, wherein: One end of the separation gas pipe (123) is fixed to the top of the inner wall of the material distribution chamber (122). The other end of the separation gas pipe (123) passes through the aggregate pool (124) and extends to the outside of the aggregate pool (124). Moreover, a plurality of ventilation holes are formed at the position of the separation gas pipe (123) coaxial with the material distribution chamber (122).

4. A mixing device for pharmaceutical production according to claim 3, characterized in that: A fixed and sliding feeding pipe (114) is fixedly installed on the top support frame (111). The fixed and sliding feeding pipe (114) is slidably sleeved on the outer surface of the moving and sliding feeding pipe (108). The material distribution cover (121) and the fixed and sliding feeding pipe (114) are fixedly connected through a feeding guiding pipe (119). A connecting valve (120) is installed in series on the feeding guiding pipe (119). The feeding guiding pipe (119) is fixedly connected to the inside of the second conical guiding cover (127) through the feeding guiding side pipe (126).

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