Drug microorganism detection device
By designing a semi-automated drug microbial detection device, the automatic dilution of drugs and the application of Petri dishes is achieved using rotating motors and gear systems, the problem of inefficiency of traditional methods is solved and the detection efficiency is improved.
Patent Information
- Application Number
- CN202411420672.8
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2024-10-12
- Publication Date
- 2025-01-07
- Estimated Expiration
- Not applicable · inactive patent
AI Technical Summary
Traditional drug microbial detection methods mainly rely on manual operations, especially when dealing with large amounts of drugs, and lack automated solutions.
A drug microbial detection device is designed, which has semi-automated functions, which can simultaneously perform dilution and petri dish application operations, and a rotating motor drive support plate and gear system realizes uniform mixing of diluents and automatic coating of petri dishes.
It realizes automatic dilution of drugs and Petri dish coating, saves the time and energy of inspectors, improves the detection efficiency, and replaces traditional manual operations.
Smart Images

Figure CN119265023A_ABST
Abstract
Description
Technical Field
[0001] The present invention relates to the technical field of microorganism detection, and in particular to a drug microorganism detection device. Background Art
[0002] The microbial limit test of drugs is a method for checking the degree of microbial contamination of non-sterile preparations and their raw materials. It is an important test for controlling and improving the quality of drugs, and is also an important indicator for controlling the quality of hospital preparations. Among them, the microbial colony counting method is a commonly used microbial detection method. The main steps are to dilute the treated sample liquid and oscillate and mix it, then take an appropriate amount of diluent and add it to the solidified culture medium plate, and evenly apply it with a sterile cotton swab to make the sample fully contact with the culture medium, and then culture it. At present, the above operations of this detection method are mainly completed manually. When the number of drugs to be tested is relatively large, such a traditional method that relies entirely on manual completion is undoubtedly inefficient. Therefore, it is very necessary to develop a device that can perform the above operations in batches. Summary of the invention
[0003] In view of the above problems, the present invention provides a drug microorganism detection device, which can perform semi-automatic dilution and culture dish smearing operations on multiple drugs at the same time, saving time and labor.
[0004] In order to solve the above technical problems, the present invention provides a drug microorganism detection device, including a detection box, a lid is provided on the top of the detection box, a control panel and an alarm light are provided on the outer wall of the detection box, a support plate 1 movable along the width direction of the detection box is provided in the detection box, and a support plate 2 bonded to the support plate 1 is provided on one side of the support plate 1; a carrier is provided on the top of the support plate 1, the cross section of the carrier is semicircular, a rack 1 is provided on the top of the support plate 1, and a rack 2 meshed with the rack 1 is provided on the bottom surface of the carrier; fixed blocks are provided on the tops of both ends of the carrier, and the two fixed blocks are arranged along the length direction of the detection box, and the inner wall of the detection box is provided with two accommodating grooves, and the two fixed blocks are respectively located in the two accommodating grooves; a plurality of hollow and spherical ball cups are provided on the top of the carrier, which are equidistantly arranged along the length direction of the detection box and detachably connected to the carrier, and an opening is provided on the top of the ball cup, and a liquid outlet pipe 1 inclined toward the side where the support plate 2 is located and connected to the ball cup is provided on the side of the ball cup facing the side where the support plate 2 is located;
[0005] The top of the second support plate is provided with a plurality of discs equidistantly arranged along the length direction of the detection box, and the top of the disc is provided with a culture dish detachably connected to the disc; a support seat is provided between the disc and the second support plate, and the outer wall of the support seat is provided with a gear which is arranged around the support seat and can rotate around the support seat, and the gear can drive the disc to tilt to one side when it rotates; a plurality of horizontal rods equidistantly arranged along the length direction of the detection box are provided on the side of the second support plate away from the first support plate, and a horizontally arranged U-shaped tube one is provided at one end of the horizontal rod away from the second support plate, a piston one is provided at one end of the horizontal rod located in the U-shaped tube one, a piston two is provided in one end of the U-shaped tube one away from the piston one, and a push rod extending out of the U-shaped tube one is provided on a side of the second piston facing the second support plate, and an end of the push rod away from the U-shaped tube one extends to the gear, and a side of the push rod facing the gear is meshed with the gear;
[0006] A liquid storage bottle is provided in the detection box, a water pump and a liquid inlet are provided on the top of the liquid storage bottle, a liquid inlet pipe 1 is provided at the water inlet of the water pump, the liquid inlet penetrates into the liquid storage bottle and extends to the bottom of the liquid storage bottle, a liquid outlet pipe 2 is provided at the water outlet of the water pump, a channel 1 is provided on the inner wall of the detection box, the liquid outlet pipe 2 is connected with the channel 1, a channel 2 connected with the channel 1 is provided on the cover, a liquid separation chamber 1 is provided at one end of the channel 2 away from the channel 1, and a plurality of channels 3 facing a plurality of ball cups are provided at the bottom of the liquid separation chamber 1.
[0007] Furthermore, a rotating motor is provided at the bottom of the detection box, a threaded rod is provided on the side of the rotating motor facing the support plate one, a support rod one is provided at the bottom of the support plate one, the threaded rod passes through the support rod one and is threadedly connected with the support rod one, and a strip slide groove one is provided on the bottom surface of the detection box along the width direction of the detection box, and the bottom end of the support rod one is located in the strip slide groove one.
[0008] Furthermore, a second support rod is provided at the bottom of the second support plate, and a second strip slide groove is provided on the bottom surface of the detection box along the width direction of the detection box, and the bottom end of the second support rod is located in the second strip slide groove.
[0009] Furthermore, the top surface of the carrier is provided with a plurality of semi-spherical fixing grooves 1 which are equidistantly arranged along the length direction of the detection box, and the ball cup is embedded in the fixing grooves 1.
[0010] Furthermore, a second fixing groove is provided on the top of the disc, and the bottom end of the culture dish is embedded in the second fixing groove.
[0011] Furthermore, a semi-spherical part is provided at the center of the bottom of the disc, a groove is provided at the top of the support seat, the cross-section of the groove is arc-shaped, the bottom end of the semi-spherical part is located in the groove, and a spring is provided between the semi-spherical part and the groove; an annular slider is provided on the inner side wall of the gear, and an annular groove is provided on the outer side wall of the support seat for the annular slider to slide along the annular direction of the gear; an annular groove 2 is provided at the bottom of the disc, which is arranged in an annular manner around the semi-spherical part, and an annular slider 2 is provided in the annular groove 2, and a pull rope connected to the bottom of the annular slider 2 is provided on the top of the gear 1, and the pull rope pulls the disc to tilt toward the side where the pull rope is located.
[0012] Furthermore, the liquid inlet is provided with a sealing plug.
[0013] Furthermore, the cover is provided with perforations on both sides, the outer wall of the detection box is provided with a slot, the perforations are provided with fixing rods that pass through the perforations and are inserted into the slots; the top of the side wall of the detection box is provided with an annular leak-proof groove arranged around a channel, the inner wall of the leak-proof groove is provided with a sealing gasket, and the bottom surface of the cover is provided with an annular plate inserted into the leak-proof groove.
[0014] Furthermore, a vertically arranged and inverted U-shaped tube 2 is provided on the top of the U-shaped tube 1, the U-shaped tube 2 is connected to one end of the U-shaped tube 1 provided with a piston 1, the end of the U-shaped tube 2 away from the U-shaped tube 1 is provided with a horizontal tube, and the end of the horizontal tube away from the U-shaped tube 2 is provided with a vertically arranged dilution tube; a piston 3 is provided in the end of the U-shaped tube 2 close to the U-shaped tube 1, a piston 4 is provided at the bottom of the dilution tube, an end of the U-shaped tube 2 close to the U-shaped tube 1 is provided with an electromagnetic valve 1, and the electromagnetic valve 1 is located between the piston 3 and the U-shaped tube 1; a channel 4 connected with the channel 2 is provided in the cover, an electromagnetic valve 2 is provided at the connection between the channel 4 and the channel 2 and the liquid separation chamber 1, a liquid separation chamber 2 is provided at the end of the channel 4 away from the channel 2, a plurality of channels 5 facing the plurality of dilution tubes are provided at the bottom of the liquid separation chamber 2, and the channel 4 is provided with an electromagnetic valve 3.
[0015] Furthermore, the U-shaped tube 2 includes a straight tube close to the U-shaped tube 1 and a handle-shaped tube away from the U-shaped tube 1, and the outer wall of the connection between the straight tube and the handle-shaped tube is provided with a fixing tube, and the fixing tube is threadedly connected to the outer walls of the straight tube and the handle-shaped tube.
[0016] Compared with the prior art, the beneficial effects of the present invention are as follows: the present invention can automatically dilute and mix the medicine, and automatically apply the diluent on the culture dish, and make the diluent fully contact with the culture medium in the culture dish; the driving performance of the rotating motor of the present invention can complete both the mixing operation of the diluted sample and the coating operation of the culture dish; the present invention can also highly dilute the sample, the present invention is easy to operate, and can replace manual dilution, mixing and coating operations, which can save a lot of time and effort of the inspector, so that the inspector has more time and energy to complete other experimental operations. BRIEF DESCRIPTION OF THE DRAWINGS
[0017] Figure 1 The internal structure of the main view of the present invention (with reference numerals);
[0018] Figure 2 for Figure 1 A schematic diagram of the structure at A;
[0019] Figure 3 for Figure 1 A schematic diagram of the structure at B;
[0020] Figure 4 The internal structure of the support plate 1 and the carrier body of the present invention is shown in the right view;
[0021] Figure 5 A top view of the support plate 2 of the present invention;
[0022] Figure 6 It is a schematic diagram of the connection structure of the gear, the second support plate and the first U-shaped tube of the present invention;
[0023] Figure 7 A top view of a U-shaped tube 1 of the present invention;
[0024] Figure 8 The internal structure of the front view of the support plate 2 and the disc part of the present invention;
[0025] Fig. 9 for Figure 8 The schematic diagram of the structure at C;
[0026] Fig.10 The internal structure of the front view of the present invention (not marked with reference numerals);
[0027] Among them: 1. detection box; 2. cover; 3. control panel; 4. alarm light; 5. support plate 1; 6. support plate 2; 7. carrier; 8. rack 1; 9. rack 2; 10. fixed block; 11. receiving groove; 12. ball cup; 13. opening; 14. liquid outlet pipe 1; 15. support seat; 16. gear; 17. disc; 18. culture dish; 19. horizontal rod; 20. U-shaped tube 1; 21. piston 1; 22. piston 2; 23. push rod; 24. liquid storage bottle; 25. water pump; 26. liquid inlet; 27. liquid inlet pipe 1; 28. liquid outlet pipe 2; 29. channel 1; 30. channel 2; 31. liquid separation chamber 1; 32. channel 3; 33. rotating motor; 34. threaded rod; 35. support rod 1; 36 , strip slide one; 37, support rod two; 38, strip slide two; 39, fixed groove one; 40, fixed groove two; 41, semi-spherical part; 42, groove; 43, spring; 44, annular slider one; 45, annular slide one; 46, annular slider two; 47, annular slide two; 48, pull rope; 49, sealing plug; 50, perforation; 51, slot; 52, fixing rod; 53, leakproof groove; 54, sealing gasket; 55, annular plate; 56, horizontal tube; 57, dilution tube; 58, piston three; 59, piston four; 60, solenoid valve one; 61, channel four; 62, solenoid valve two; 63, liquid separation chamber two; 64, channel five; 65, solenoid valve three; 66, straight tube; 67, umbrella handle tube; 68, fixed tube. DETAILED DESCRIPTION
[0028] In order to make the objectives, technical solutions and advantages of the present invention more clearly understood, the present invention is further described in detail below in conjunction with embodiments and drawings. The exemplary embodiments of the present invention and their description are only used to explain the present invention and are not intended to limit the present invention.
[0029] Example:
[0030] See attached Figure 1 To Attachment Fig.10 A drug microorganism detection device includes a detection box 1, a cover 2 is provided on the top of the detection box 1, a control panel 3 and an alarm light 4 are provided on the outer wall of the detection box 1, a support plate 5 that can move along the width direction of the detection box 1 is provided in the detection box 1, and a support plate 2 6 bonded to the support plate 1 5 is provided on one side of the support plate 1 5. When the support plate 1 5 moves along the width direction of the detection box 1, the support plate 2 6 also moves along the width direction of the detection box 1 with the support plate 1 5.
[0031] A rotating motor 33 is provided at the bottom of the detection box 1. A threaded rod 34 connected to the output shaft end of the rotating motor 33 is provided on the side of the rotating motor 33 facing the side where the support plate 1 5 is located. A support rod 1 35 is provided at the bottom of the support plate 1 5. The support rod 1 35 is bonded to the support plate 1 5. The threaded rod 34 passes through the support rod 1 35 and is threadedly screwed to the support rod 1 35. A strip slide 1 36 is provided on the bottom surface of the detection box 1 along the width direction of the detection box 1. The bottom end of the support rod 1 35 is located in the strip slide 1 36. The support rod 1 35 can slide in the strip slide 1 36. A support rod 2 37 is provided at the bottom of the support plate 2 6. The support rod 2 37 is bonded to the support plate 2 6. A strip slide 2 38 is provided on the bottom surface of the detection box 1 along the width direction of the detection box 1. The bottom end of the support rod 2 37 is located in the strip slide 2 38. The support rod 2 37 can slide in the strip slide 2 38.
[0032] A carrier 7 is provided on the top of the support plate 5, and the cross section of the carrier 7 is semicircular, and the length direction of the carrier 7 is arranged along the length direction of the detection box 1. A rack 8 is provided on the top of the support plate 5, and a rack 29 meshing with the rack 8 is provided on the bottom surface of the carrier 7. The rack 8 and the rack 29 are arranged in such a way that when the support plate 5 moves along the width direction of the detection box 1, the support plate 5 can drive the carrier 7 to rotate around the center of its semicircular cross section.
[0033] Fixed blocks 10 are provided at the tops of both ends of the carrier 7, and the fixed blocks 10 are bonded to the carrier 7. The two fixed blocks 10 are arranged along the length direction of the detection box 1. The inner wall of the detection box 1 is provided with two receiving grooves 11. The two fixed blocks 10 are respectively located in the two receiving grooves 11. The fixed blocks 10 can rotate in the receiving grooves 11, and the fixed blocks 10 play the role of supporting the carrier 7.
[0034] The top of the carrier 7 is provided with a plurality of hollow and spherical cups 12 which are equidistantly arranged along the length direction of the detection box 1 and are detachably connected to the carrier 7. The center of the cup 12 overlaps with the center of the cross section of the carrier 7. The top of the cup 12 is provided with an opening 13. The side of the cup 12 facing the side where the support plate 2 6 is located is provided with a liquid outlet pipe 14 which is inclined toward the side where the support plate 2 6 is located and is connected to the inside of the cup 12. The liquid outlet pipe 14 and the cup 12 are made as one piece. The diluent and the sample solution are added from the opening 13 of the cup 12. The top surface of the carrier 7 is provided with a plurality of semi-spherical fixing grooves 39 which are equidistantly arranged along the length direction of the detection box 1. The cup 12 is embedded in the fixing groove 39 and can be directly taken out of the fixing groove 39.
[0035] A plurality of discs 17 are arranged equidistantly along the length direction of the detection box 1 on the top of the second support plate 6, and a culture dish 18 is arranged on the top of the disc 17 and is detachably connected to the disc 17. A second fixing groove 40 is arranged on the top of the disc 17, and the bottom end of the culture dish 18 is embedded in the second fixing groove 40, so that the culture dish 18 can be directly taken out of the second fixing groove 40.
[0036] A support seat 15 is provided between the disc 17 and the support plate 2 6. A gear 16 is provided on the outer wall of the support seat 15 and is arranged around the support seat 15 and can rotate around the support seat 15. When the gear 16 rotates, the disc 17 can be driven to tilt to one side. A semi-spherical piece 41 is provided at the center of the bottom of the disc 17 of this embodiment. A groove 42 is provided at the top of the support seat 15. The cross section of the groove 42 is an arc shape. The arc surface of the semi-spherical piece 41, that is, its bottom end, is located in the groove 42. A spring 43 is provided between the semi-spherical piece 41 and the groove 42. The spring 43 is bonded to both the semi-spherical piece 41 and the support seat 15.
[0037] The inner wall of the gear 16 is provided with an annular slider 144, which is bonded to the gear 16. The outer wall of the support seat 15 is provided with an annular groove 145 for the annular slider 144 to slide along the annular direction of the gear 16. The bottom of the disc 17 is provided with an annular groove 247 arranged around the semi-spherical member 41. The annular slider 246 is provided in the annular groove 247. The annular slider 246 can rotate in the annular groove 247. The top of the gear 16 is provided with a pull rope 48 connected to the bottom of the annular slider 246. The pull rope 48 pulls the disc 17 to tilt toward the side where the pull rope 48 is located. The pull rope 48 is bonded to both the gear 16 and the annular slider 246.
[0038] A plurality of horizontal rods 19 are arranged equidistantly along the length direction of the detection box 1 on the side of the support plate 26 away from the support plate 15. The length direction of the horizontal rods 19 is arranged along the width direction of the detection box 1. The horizontal rods 19 are bonded to the support plate 26. A horizontally arranged U-shaped tube 20 is arranged at one end of the horizontal rod 19 away from the support plate 26. A piston 21 is arranged at one end of the horizontal rod 19 located in the U-shaped tube 20. The horizontal rod 19 is bonded to the piston 21. A piston 22 is arranged in one end of the U-shaped tube 20 away from the piston 21. A push rod 23 extending out of the U-shaped tube 20 is arranged on one side of the piston 22 facing the support plate 26. The push rod 23 is bonded to the piston 22. The end of the push rod 23 away from the U-shaped tube 20 extends to the gear 16. The side of the push rod 23 facing the gear 16 is meshed with the gear 16. When the support plate 26 moves back and forth along the width direction of the detection box 1, the push rod 23 pushes the gear 16, thereby driving the gear 16 to rotate, thereby pulling the annular slider 246 with the pull rope 48 to rotate, so that the disk 17360° continuously tilts, thereby evenly coating the diluted sample liquid in the culture dish 18 on the surface of the culture medium.
[0039] A liquid storage bottle 24 is provided in the detection box 1. A water pump 25 and a liquid inlet 26 are provided on the top of the liquid storage bottle 24. The liquid inlet 26 is provided with a sealing plug 49. The diluent is added into the liquid storage bottle 24 through the liquid inlet 26. The water inlet of the water pump 25 is provided with a liquid inlet pipe 1 27 that penetrates into the liquid storage bottle 24 and extends to the bottom of the liquid storage bottle 24. The water outlet of the water pump 25 is provided with a liquid outlet pipe 2 28. The inner wall of the detection box 1 is provided with a channel 1 29 that passes through the top of the side wall of the detection box 1. The liquid outlet pipe 2 28 is connected to the channel 1 29. The liquid outlet pipe 2 28 is bonded to the inner side wall of the detection box 1. The cover 2 is provided with a channel 2 30 that is connected to the channel 1 29. A liquid separation chamber 1 31 is provided at one end of the channel 2 30 away from the channel 1 29. A plurality of channels 3 32 that are directly opposite to the plurality of ball cups 12 are provided at the bottom of the liquid separation chamber 1 31.
[0040] In order to facilitate the lid 2 to be tightly pressed on the top of the detection box 1, the present embodiment has perforations 50 on both sides of the lid 2, and a slot 51 is provided on the outer side wall of the detection box 1. The perforations 50 are provided with fixing rods 52 that pass through the perforations 50 and are inserted into the slot 51, thereby fixing the lid 2. The top of the side wall of the detection box 1 is provided with an annular leakproof groove 53 arranged around the channel 1 29, and the inner wall of the leakproof groove 53 is provided with a sealing gasket 54. The bottom surface of the lid 2 is provided with an annular plate 55 inserted into the leakproof groove 53, and the annular plate 55 is inserted into the leakproof groove 53 provided with the sealing gasket 54, which can further prevent the diluent from leaking out from the connection between the channel 1 29 and the channel 2 30.
[0041] In order to facilitate high dilution, a vertically arranged and inverted U-shaped tube 2 is provided on the top of the U-shaped tube 1 20 in this embodiment. One end of the U-shaped tube 2 is connected to one end of the U-shaped tube 1 provided with a piston 1 21. A horizontal tube 56 is provided at one end of the U-shaped tube 2 away from the U-shaped tube 1 20. A vertically arranged dilution tube 57 is provided at one end of the horizontal tube 56 away from the U-shaped tube 2. The U-shaped tube 2 includes a straight tube 66 close to the U-shaped tube 1 20 and a handle-shaped tube 67 away from the U-shaped tube 1 20. The handle-shaped tube 67 includes the bend of the U-shaped tube 2. A fixed tube 68 is provided on the outer wall of the connection between the straight tube 66 and the handle-shaped tube 67. The fixed tube 68 is threadedly connected to the outer walls of the straight tube 66 and the handle-shaped tube 67. The dilution tube 57 and the handle-shaped tube 67 are made in one piece. The handle-shaped tube 67 and the dilution tube 57 can be removed together for cleaning and sterilization.
[0042] A piston 3 58 is provided in one end of the U-shaped tube 2 near the U-shaped tube 1 20, and the piston 3 58 is provided in the straight tube 66. A piston 4 59 is provided at the bottom of the dilution tube 57. A solenoid valve 1 60 is provided at one end of the U-shaped tube 2 near the U-shaped tube 1 20, and the solenoid valve 1 60 is located between the piston 3 58 and the U-shaped tube 1 20.
[0043] The cover 2 is also provided with a channel 4 61 connected to the channel 2 30, and a solenoid valve 2 62 is provided at the channel 2 30 between the connection between the channel 4 61 and the channel 2 30 and the liquid separation chamber 1 31. A liquid separation chamber 2 63 is provided at one end of the channel 4 61 away from the channel 2 30, and a plurality of channels 5 64 are provided at the bottom of the liquid separation chamber 2 63, which are directly opposite to the plurality of dilution tubes 57, and a solenoid valve 3 65 is provided at the channel 4 61.
[0044] The use principle of this embodiment is as follows: if the dilution using the ball cup 12 alone cannot meet the requirements and a higher degree of dilution is required, then when in use, the drug sample to be diluted is added to the dilution tube 57, the lid 2 is covered, and the working parameters of the rotating motor 33 and the water pump 25 are set through the control panel 3. At this time, the ball cup 12 is in a vertical state, the electromagnetic valve 2 62 is closed, the electromagnetic valve 3 65 is turned on, and the water pump 25 is turned on to pump a certain amount of diluent into the channel 5 64 through the channel 1 29, the channel 2 30 and the channel 4 61, so that the diluent is added to the dilution tube 57, and then the rotating motor 33 is turned on to drive the support plate 2 6 and the support plate 1 5 to move back and forth along the width direction of the detection box 1, the support plate 2 6 pushes the horizontal rod 19, and the horizontal rod 19 pushes the piston 1 21 to move. At this time, the electromagnetic valve 1 60 is in an open state, and the piston 1 21 pushes the piston 2 22 to do a meaningless action at this time. When the piston 3 58 and the piston 4 59 are moved, the piston 4 59 pushes the liquid in the dilution tube 57 to move up and down, thereby mixing the diluent and the drug sample liquid; after the mixing is completed, the alarm light 4 is turned on to remind the staff to complete the dilution work. At this time, the support plate 1 5 returns to the original position and waits for the next step; the inspector opens the cover 2, manually transfers a certain amount of liquid in the dilution tube 57 into the ball cup 12, covers the cover 2 again, sets the operation mode of the rotating motor 33 and the water pump 25 through the control panel 3, closes the solenoid valve 3 65 and the solenoid valve 1 60, opens the solenoid valve 2 62, turns on the water pump 25, pumps the diluent from the liquid storage bottle 24 into the ball cup 12, and then turns on the rotating motor 33. At this time, the rotating motor 33 plays the role of mixing the drug sample liquid in the ball cup 12, and the rotating motor 33 drives the support plate 1 5 to move back and forth, thereby driving the carrier 7 to rotate back and forth, thereby mixing the liquid in the ball cup 12;
[0045] After the mixing is completed, the rotating motor 33 drives the support plate 5 to move toward the side away from the U-shaped tube 20, and the ball cup 12 rotates clockwise. At this time, the support plate 26 and the culture dish 18 are close to the side where the ball cup 12 is located. At the same time, the liquid outlet pipe 14 rotates toward the direction of the support plate 5. When the liquid in the ball cup 12 reaches the connection between the liquid outlet pipe 14 and the ball cup 12 as the ball cup 12 rotates, the liquid in the ball cup 12 flows out from the liquid outlet pipe 14. At this time, the culture dish 18 has moved to the bottom of the end of the liquid outlet pipe 14 away from the ball cup 12. At this time, the liquid flowing out of the liquid outlet pipe 14 flows into the culture dish 18. When the liquid flowing into the culture dish 18 reaches the set amount, the rotating motor 33 drives the support plate 5 to move toward the side close to the U-shaped tube 20, and the ball cup 12 is moved straight again;
[0046] Then the rotating motor 33 drives the support plate 5 to move toward the side where the U-shaped tube 20 is located, and then drives the support plate 5 to move toward the side away from the U-shaped tube 20, and so on. During this process, the push rod 23 pushes the gear 16, driving the gear 16 to rotate, thereby pulling the annular slider 46 with the pull rope 48 to rotate, so that the disc 17360° is continuously tilted to achieve the purpose of evenly coating the diluted sample liquid in the culture dish 18 on the surface of the culture medium; after completing this step, open the cover 2, take out the culture dish 18 for culture, and then replace the next group of culture dishes 18, repeat adding the sample liquid to the next group of culture dishes 18 and evenly coating it; the water pump 25 of this embodiment controls the pumping amount of the diluent can be calculated in advance according to the pumping force, time and length and diameter of each channel of the water pump 25, and set it in the control panel 3. This measurement technology is a prior art and can be pre-measured according to the size and specifications of the actual product, so there is no need to set a flow sensor.
[0047] The above is an embodiment of the present invention. The above embodiments and the specific parameters in the embodiments are only for the purpose of clearly describing the invention verification process, and are not intended to limit the patent protection scope of the present invention. The patent protection scope of the present invention is still subject to its claims. Any equivalent structural changes made by using the contents of the description and drawings of the present invention should be included in the protection scope of the present invention.
Claims
1. A drug microbial detection device, characterized in that: The invention comprises a detection box (1), wherein a cover (2) is provided on the top of the detection box (1), a control panel (3) and an alarm light (4) are provided on the outer wall of the detection box (1), a support plate (5) movable along the width direction of the detection box (1) is provided inside the detection box (1), a support plate (6) bonded to the support plate (5) is provided on one side of the support plate (5); a carrier (7) is provided on the top of the support plate (5), the cross section of the carrier (7) is semicircular, a rack (8) is provided on the top of the support plate (5), and a rack (9) meshing with the rack (8) is provided on the bottom surface of the carrier (7); two ends of the carrier (7) are provided. A fixing block (10) is provided on the top, and two of the fixing blocks (10) are arranged along the length direction of the detection box (1). Two receiving grooves (11) are provided on the inner wall of the detection box (1), and the two fixing blocks (10) are respectively located in the two receiving grooves (11); a plurality of hollow and spherical ball cups (12) are provided on the top of the carrier (7), which are equidistantly arranged along the length direction of the detection box (1) and detachably connected to the carrier (7); an opening (13) is provided on the top of the ball cup (12); and a liquid outlet pipe (14) is provided on the side of the ball cup (12) facing the side where the second support plate (6) is located, which is inclined toward the side where the second support plate (6) is located and is connected to the inside of the ball cup (12); A plurality of discs (17) are arranged at equal distances along the length direction of the detection box (1) on the top of the second support plate (6); a culture dish (18) is arranged on the top of the disc (17) and is detachably connected to the disc (17); a support seat (15) is arranged between the disc (17) and the second support plate (6); a gear (16) is arranged around the support seat (15) and can rotate around the support seat (15) on the outer wall of the support seat (15); when the gear (16) rotates, it can drive the disc (17) to tilt to one side; a plurality of discs (17) are arranged at equal distances along the length direction of the detection box (1) on the side of the second support plate (6) away from the first support plate (5); A horizontal rod (19) is provided, and a horizontally arranged U-shaped tube (20) is provided at one end of the horizontal rod (19) away from the supporting plate (6), and a piston (21) is provided at one end of the horizontal rod (19) located in the U-shaped tube (20), and a piston (22) is provided in one end of the U-shaped tube (20) away from the piston (21), and a push rod (23) extending out of the U-shaped tube (20) is provided on a side of the piston (22) facing the supporting plate (6), and the end of the push rod (23) away from the U-shaped tube (20) extends to the gear (16), and the side of the push rod (23) facing the gear (16) is meshed with the gear (16); The detection box (1) is provided with a liquid storage bottle (24), the top of the liquid storage bottle (24) is provided with a water pump (25) and a liquid inlet (26), the water inlet of the water pump (25) is provided with a liquid inlet pipe (27) that penetrates into the liquid storage bottle (24) and extends to the bottom of the liquid storage bottle (24), the water outlet of the water pump (25) is provided with a liquid outlet pipe (28), the inner wall of the detection box (1) is provided with a channel (29) that passes through the top of the side wall of the detection box (1), the liquid outlet pipe (28) is connected with the channel (29), the cover (2) is provided with a channel (30) that is connected with the channel (29), the end of the channel (30) away from the channel (29) is provided with a liquid separation chamber (31), and the bottom of the liquid separation chamber (31) is provided with a plurality of channels (32) that are directly opposite to the plurality of ball cups (12).
2. A drug microorganism detection device according to claim 1, characterized in that: A rotating motor (33) is provided at the bottom of the detection box (1), a threaded rod (34) is provided on the side of the rotating motor (33) facing the side where the support plate (5) is located, a support rod (35) is provided at the bottom of the support plate (5), the threaded rod (34) passes through the support rod (35) and is threadedly connected to the support rod (35), and a strip-shaped slide groove (36) is provided on the bottom surface of the detection box (1) along the width direction of the detection box (1), and the bottom end of the support rod (35) is located in the strip-shaped slide groove (36).
3. A drug microorganism detection device according to claim 1, characterized in that: A second support rod (37) is provided at the bottom of the second support plate (6), and a second strip-shaped slide groove (38) is provided on the bottom surface of the detection box (1) along the width direction of the detection box (1), and the bottom end of the second support rod (37) is located in the second strip-shaped slide groove (38).
4. A drug microorganism detection device according to claim 1, characterized in that: The top surface of the carrier (7) is provided with a plurality of semi-spherical fixing grooves (39) which are arranged equidistantly along the length direction of the detection box (1), and the ball cup (12) is embedded in the fixing grooves (39).
5. A drug microorganism detection device according to claim 1, characterized in that: A second fixing groove (40) is provided on the top of the circular disc (17), and the bottom end of the culture dish (18) is embedded in the second fixing groove (40).
6. A drug microorganism detection device according to claim 1, characterized in that: A semi-spherical member (41) is provided at the center of the bottom of the disc (17); a groove (42) is provided at the top of the support seat (15); the cross section of the groove (42) is arc-shaped; the bottom end of the semi-spherical member (41) is located in the groove (42); a spring (43) is provided between the semi-spherical member (41) and the groove (42); an annular slider (44) is provided on the inner side wall of the gear (16); and a spring (43) is provided on the outer side wall of the support seat (15) for the annular slider (44). 44) an annular slide groove (45) sliding along the annular direction of the gear (16); the bottom of the disc (17) is provided with an annular slide groove (47) arranged around the semi-spherical member (41), and an annular slider (46) is arranged in the annular slide groove (47); the top of the gear (16) is provided with a pull rope (48) connected to the bottom of the annular slider (46), and the pull rope (48) pulls the disc (17) to tilt toward the side where the pull rope (48) is located.
7. A drug microorganism detection device according to claim 1, characterized in that: The liquid inlet (26) is provided with a sealing plug (49).
8. A drug microorganism detection device according to claim 1, characterized in that: The cover (2) is provided with perforations (50) on both sides, the outer wall of the detection box (1) is provided with a slot (51), and the perforation (50) is provided with a fixing rod (52) which passes through the perforation (50) and is inserted into the slot (51); the top of the side wall of the detection box (1) is provided with an annular leak-proof groove (53) arranged around the channel 1 (29), the inner wall of the leak-proof groove (53) is provided with a sealing gasket (54), and the bottom surface of the cover (2) is provided with an annular plate (55) inserted into the leak-proof groove (53).
9. A drug microorganism detection device according to claim 1, characterized in that: A vertically arranged and inverted U-shaped tube 2 is provided on the top of the U-shaped tube 1 (20); the U-shaped tube 2 is connected to one end of the U-shaped tube 1 provided with a piston 1 (21); the end of the U-shaped tube 2 away from the U-shaped tube 1 (20) is provided with a horizontal tube (56); the end of the horizontal tube (56) away from the U-shaped tube 2 is provided with a vertically arranged dilution tube (57); a piston 3 (58) is provided in the end of the U-shaped tube 2 close to the U-shaped tube 1 (20); a piston 4 (59) is provided at the bottom of the dilution tube (57); an end of the U-shaped tube 2 close to the U-shaped tube 1 (20) is provided with an electromagnetic valve 1 (60); the electromagnetic valve 1 (60) is provided at the end of the U-shaped tube 2 close to the U-shaped tube 1 (2 ... The magnetic valve 1 (60) is located between the piston 3 (58) and the U-shaped tube 1 (20); the cover (2) is provided with a channel 4 (61) connected to the channel 2 (30); a solenoid valve 2 (62) is provided at the channel 2 (30) between the connection between the channel 4 (61) and the channel 2 (30) and the liquid separation chamber 1 (31); a liquid separation chamber 2 (63) is provided at one end of the channel 4 (61) away from the channel 2 (30); a plurality of channels 5 (64) are provided at the bottom of the liquid separation chamber 2 (63) and are directly opposite to the plurality of dilution tubes (57); and the channel 4 (61) is provided with a solenoid valve 3 (65).
10. A drug microorganism detection device according to claim 9, characterized in that: The U-shaped tube (2) comprises a straight tube (66) close to the U-shaped tube (20) and a handle-shaped tube (67) far from the U-shaped tube (20). A fixing tube (68) is provided on the outer side wall of the connection between the straight tube (66) and the handle-shaped tube (67). The fixing tube (68) is threadedly connected to the outer side walls of the straight tube (66) and the handle-shaped tube (67).