Cerebrospinal fluid sampling device for lymphoma detection
By designing a cerebrospinal fluid sampling device with a rotating disc and an electric push rod, the problem of liquid dripping during test tube collection is solved, and a more stable and convenient sampling process is achieved.
Patent Information
- Application Number
- CN202411397243.3
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2024-10-08
- Publication Date
- 2025-01-10
- Estimated Expiration
- Not applicable · inactive patent
AI Technical Summary
In the prior art, when cerebrospinal fluid is fed through test tubes, the patient's slight movement causes the fluid position to shift, which easily leads to cerebrospinal fluid dripping, making it less convenient and practical.
A cerebrospinal fluid sampling device including a puncture needle and a work box is designed, and components such as rotating discs, special-shaped clamping blocks, motors and electric push rods are used to achieve stable clamping and rotation of the test tube to prevent liquid from dripping.
It improves the stability and practicality of use, ensures the safe, effective collection and transfer of cerebrospinal fluid, and enhances the reliability of operation.
Smart Images
Figure CN119279640A_ABST
Abstract
Description
Technical Field
[0001] The present invention relates to the technical field of lymphoma detection, and in particular to a cerebrospinal fluid sampling device for lymphoma detection. Background Art
[0002] Cerebrospinal fluid surrounds and supports the central nervous system. It is a colorless, transparent liquid that fills the ventricles, subarachnoid space, and central canal of the spinal cord, totaling about 130-150 mL. Cerebrospinal fluid is in direct contact with the central nervous system and is an ideal biological sample for detecting characteristic proteins of CNS diseases. It is also an important source for finding potential biomarkers for CNS diseases. Cerebrospinal fluid is often used in clinical testing and multi-omics analysis of genomes, proteomes, metabolomes, cytology, and other studies. It can be used to assist in the diagnosis of diseases such as central nervous system infections, subarachnoid hemorrhage, immune inflammatory diseases, demyelinating diseases, and meningeal cancer.
[0003] After successful lumbar puncture, the cerebrospinal fluid pressure is measured immediately, and then the cerebrospinal fluid samples are collected in 3 sterile test tubes, 1 to 2 ml in each test tube. The first tube is used for pathogenic biological testing, the second tube is used for chemical and immunological testing, and the third tube is used for physical and cytological testing.
[0004] The existing method of sampling cerebrospinal fluid specimens requires collecting cerebrospinal fluid by hand through a test tube. During the process of collecting through the test tube, the patient's slight movement will cause the position of the cerebrospinal fluid to shift, which may easily cause the cerebrospinal fluid to drip out of the mouth of the test tube, and the convenience and practicality of use are low. Summary of the invention
[0005] 1. Technical issues to be resolved
[0006] In view of the shortcomings of the prior art, the present invention provides a cerebrospinal fluid sampling device for lymphoma detection to solve the problem that in the process of collecting cerebrospinal fluid through a test tube in the prior art proposed in the background technology, a slight movement of the patient will cause the position of the cerebrospinal fluid to shift, which may easily cause the cerebrospinal fluid to drip out of the test tube mouth, resulting in low convenience and practicality.
[0007] (II) Technical solution
[0008] To achieve the above-mentioned purpose, the present invention provides the following technical solutions: a cerebrospinal fluid sampling device for lymphoma detection, comprising a puncture needle and a working box, wherein the inner lower side wall of the working box is rotatably connected to a rotating disk, a plurality of connecting rods are fixedly connected to the top of the rotating disk, a fixed plate is fixedly connected to one end of the plurality of connecting rods away from the rotating disk, three groups of adjustment mechanisms are installed on the fixed plate, the adjustment mechanism comprises a special-shaped clamping block, three first sliding grooves are provided on the fixed plate, a first sliding block is slidably connected in the first sliding groove, the top of the first sliding block is fixedly connected to the special-shaped clamping block, the bottom end of the first sliding block is connected to a U-shaped connecting block, a first motor is installed on the top of the rotating disk, a screw is connected to the output end of the first motor, and the other end of the screw is connected to the fixed plate The fixed plate is rotatably connected, and an adjusting block is screwed on the screw rod, and three connecting plates are rotatably connected to the adjusting block, and the other end of the connecting plate is rotatably connected to the adjusting block. A cap is hinged on the top of the working box through a hinge, and a through hole is provided on the cap that penetrates up and down. A connecting hose is provided in the through hole, and the top of the connecting hose is connected to the puncture needle. A sleeve is fixedly connected to the top of the cap, and the sleeve is communicated with the through hole. A top block is slidably connected in the sleeve, and a first electric push rod is installed on the sleeve, and the output end of the first electric push rod penetrates the sleeve and is connected to the top block. A second motor is installed on the working box, and the output end of the second motor penetrates the working box and is connected to a gear. A plurality of protrusions are evenly and fixedly connected to the top of the rotating disk, and the plurality of protrusions are all meshed with the gear.
[0009] Preferably, two arc-shaped grooves are provided on each of the three special-shaped clamping blocks, and the adjacent arc-shaped grooves on the three special-shaped clamping blocks match each other.
[0010] Preferably, the bottom end of the working box is fixedly connected to a base, the bottom end of the base is evenly fixedly connected to a plurality of fixing columns, the bottom end of the fixing columns is provided with threaded holes, threaded rods are threadedly connected in the threaded holes, and the bottom end of the threaded rods is fixedly connected to a support block.
[0011] Preferably, the bottom ends of the plurality of support blocks are fixedly connected with buffer pads.
[0012] Preferably, an annular groove is provided on the fixing plate, a swivel is rotatably sleeved on the annular groove, and the swivel is fixedly connected to the inner wall of the working box.
[0013] Preferably, the cover cap is provided with an installation opening, and a transparent observation plate is installed in the installation opening.
[0014] Preferably, the sleeve is provided with a plurality of guide holes, in which guide rods are slidably connected, the guide rods are fixedly connected to the top block, and the other ends of the plurality of guide rods are fixedly connected to a limiting plate.
[0015] Preferably, a handle is fixedly connected to the cover cap, and the cover cap is connected to the working box via a hasp lock.
[0016] Preferably, six second sliding grooves are opened on the fixed plate, and second sliding blocks are slidably connected in the second sliding grooves. The six second sliding blocks are respectively fixedly connected to three special-shaped clamping blocks, and the bottom ends of the six second sliding blocks are fixedly connected to the limiting blocks.
[0017] (III) Beneficial effects
[0018] Compared with the prior art, the present invention provides a cerebrospinal fluid sampling device for lymphoma detection, which has the following beneficial effects:
[0019] 1. The cerebrospinal fluid sampling device for lymphoma detection is configured such that the first motor drives the screw to rotate, and the screw drives the special-shaped clamping block to move by cooperating with the adjustment block and the connecting plate, so that the three special-shaped clamping blocks cooperate to clamp and fix the three test tubes, thereby improving the stability of use.
[0020] 2. The cerebrospinal fluid sampling device for lymphoma detection uses a puncture needle to puncture the patient's lumbar spine for sampling, so that the internal test tube can be observed through a transparent observation plate. When the sampling in the test tube is completed, the electric push rod is turned on to drive the top block to move, so that the top block applies pressure to the connecting hose to stop the sample flow inside the connecting hose, so as to prevent cerebrospinal fluid from dripping when the test tube is replaced, thereby improving practicality.
[0021] 3. The cerebrospinal fluid sampling device for lymphoma detection drives the second motor to rotate the gear, and the gear cooperates with multiple protrusions to drive the rotating disk to rotate, so as to rotate the test tube on the special-shaped clamping block 120 degrees, and then drives the top block to move through the electric push rod to separate the top block from the connecting hose, so that another test tube can be sampled and collected, thereby improving the reliability of use. BRIEF DESCRIPTION OF THE DRAWINGS
[0022] Figure 1 It is a schematic diagram of the cross-sectional structure of the present invention;
[0023] Figure 2 For the present invention Figure 1 A schematic diagram of the local enlarged structure at point A in the middle;
[0024] Figure 3 For the present invention Figure 1 A schematic diagram of the local enlarged structure at B in the middle;
[0025] Figure 4 For the present invention Figure 1 A schematic diagram of the local enlarged structure at C in the middle;
[0026] Figure 5 It is a schematic diagram of the cross-sectional structure of the internal decomposition of the present invention;
[0027] Figure 6 For the present invention Figure 5A schematic diagram of the local enlarged structure at D in the middle;
[0028] Figure 7 It is a schematic diagram of the overall structure of the present invention;
[0029] Figure 8 It is a schematic diagram of the overall structure of the present invention.
[0030] In the figure: 1. puncture needle; 2. working box; 3. rotating disk; 4. connecting rod; 5. fixing plate; 6. special-shaped clamping block; 7. first sliding block; 8. second sliding block; 9. U-shaped connecting block; 10. first motor; 11. screw; 12. adjusting block; 13. connecting plate; 14. cap; 15. connecting hose; 16. sleeve; 17. top block; 18. first electric push rod; 19. second motor; 20. gear; 21. protrusion; 22. arc groove; 23. base; 24. fixing column; 25. threaded rod; 26. support block; 27. buffer pad; 28. annular groove; 29. swivel; 30. transparent observation plate; 31. guide rod; 32. limit plate; 33. handle; 34. buckle lock. DETAILED DESCRIPTION
[0031] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.
[0032] Example
[0033] See also Figure 1-8A cerebrospinal fluid sampling device for lymphoma detection includes a puncture needle 1, through which the patient's lumbar spine is punctured. It should be noted that the puncture needle 1 is a disposable item and can be replaced. It also includes a working box 2, the inner lower side wall of the working box 2 is rotatably connected to a rotating disk 3, the top of the rotating disk 3 is fixedly connected to a plurality of connecting rods 4, and the ends of the plurality of connecting rods 4 away from the rotating disk 3 are fixedly connected to a fixing plate 5, and three groups of adjustment mechanisms are installed on the fixing plate 5, and the adjustment mechanism includes a special-shaped clamping block 6, and three test tubes are clamped and fixed by three special-shaped clamping blocks 6, and the three special-shaped clamping blocks 6 are each provided with two arc grooves 22, and the adjacent arc grooves 22 on the three special-shaped clamping blocks 6 2 cooperates with each other, and the test tube is clamped and fixed by the adjacent frontal arc grooves 22 on the three special-shaped clamping blocks 6 to improve the stability of use. Three first sliding grooves are opened on the fixed plate 5, and the first sliding block 7 is slidably connected in the first sliding groove. The top of the first sliding block 7 is fixedly connected to the special-shaped clamping block 6, and the bottom of the first sliding block 7 is connected to the U-shaped connecting block 9. The top of the rotating disk 3 is installed with a first motor 10, and the output end of the first motor 10 is connected to a screw rod 11, and the other end of the screw rod 11 is rotatably connected to the fixed plate 5. An adjusting block 12 is screwed on the screw 11, and three connecting plates 13 are rotatably connected to the adjusting block 12. The other end of the connecting plate 13 is rotatably connected to the adjusting block 12, so that the first motor 10 drives The screw rod 11 rotates, so that the screw rod 11 drives the special-shaped clamping block 6 to move through the cooperation with the adjustment block 12 and the connecting plate 13. The top of the working box 2 is hinged with a cap 14 through a hinge. The internal test tube is sealed by the cooperation of the cap 14 and the working box 2. A through hole running through the top and bottom is opened on the cap 14. A connecting hose 15 is arranged in the through hole. The top of the connecting hose 15 is connected to the puncture needle 1. By setting the connecting hose 15, the position of the puncture needle 1 can be adjusted at will. At the same time, the puncture needle 1 will not affect the working box 2 when it moves, thereby improving the sampling stability. The top of the cap 14 is fixedly connected with a sleeve 16, which is connected to the through hole, and the sleeve 16 is slidably connected with the top block 1 7. A first electric push rod 18 is installed on the sleeve 16, and the output end of the first electric push rod 18 passes through the sleeve 16 and is connected to the top block 17, so that the first electric push rod 18 drives the top block 17 to move, so that the top block 17 applies pressure to the connecting hose 15 to prevent the flow of the sample inside the connecting hose 15. A second motor 19 is installed on the working box 2, and the output end of the second motor 19 passes through the working box 2 and is connected to a gear 20. A plurality of protrusions 21 are evenly fixedly connected to the top of the rotating disk 3, and the plurality of protrusions 21 are all meshed with the gear 20, so that the second motor 19 drives the gear 20 to rotate, and the gear 20 cooperates with the plurality of protrusions 21 to drive the rotating disk 3 to rotate, so as to rotate the test tube on the special-shaped clamping block 6.
[0034] It should also be noted that a base 23 is fixedly connected to the bottom end of the working box 2, and a plurality of fixing columns 24 are evenly fixedly connected to the bottom end of the base 23. A threaded hole is provided at the bottom end of the fixing column 24, and a threaded rod 25 is threadedly connected in the threaded hole. A supporting block 26 is fixedly connected to the bottom end of the threaded rod 25. The threaded rod 25 is rotated by the supporting block 26, so that the cooperation of the plurality of threaded rods 25 can adjust the balance of the device to improve practicality. The bottom ends of the plurality of supporting blocks 26 are all fixedly connected with a buffer pad 27. By providing the buffer pad, the buffer pad 27 can buffer the device to reduce the bump of the device. An annular groove 28 is provided on the fixing plate 5, and a swivel 29 is rotatably sleeved on the annular groove 28. The swivel 29 is fixedly connected to the inner wall of the working box 2. The cooperation of the annular groove 28 and the swivel 29 can reduce the shaking generated when the fixing plate 5 rotates, and improve the rotation stability of the fixing plate 5. An installation opening is provided on the cover cap 14, and a mounting hole is installed in the installation opening. A transparent observation plate 30 is provided, and the transparent observation plate 30 is provided to facilitate observation of the internal test tube through the transparent observation plate 30. A plurality of guide holes are provided on the sleeve 16, and a guide rod 31 is slidably connected in the guide hole. The guide rod 31 is fixedly connected to the top block 17, and the other ends of the plurality of guide rods 31 are fixedly connected to the limiting plate 32. The top block 17 is guided by the cooperation of the plurality of guide rods 31, and the guide rod 31 is limited by the limiting plate 32. A handle 33 is fixedly connected to the cap 14, and the handle 33 is used to facilitate the movement of the device, and the cap 14 is connected to the working box 2 by a buckle lock 34. Six second sliding grooves are provided on the fixed plate 5, and second sliding blocks 8 are slidably connected in the second sliding grooves. The six second sliding blocks 8 are fixedly connected to the three special-shaped clamping blocks 6 respectively, and the three special-shaped clamping blocks 6 are guided by the six second sliding blocks 8. The bottom ends of the six second sliding blocks 8 are fixedly connected to the limiting blocks.
[0035] In summary, the working principle and working process of the cerebrospinal fluid sampling device for lymphoma detection are as follows: when in use, first move the device to the desired position, place three test tubes between the three special-shaped clamping blocks 6, then turn on the first motor 10, so that the first motor 10 drives the screw 11 to rotate, so that the screw 11 drives the special-shaped clamping block 6 to move by cooperating with the adjustment block 12 and the connecting plate 13, so that the three special-shaped clamping blocks 6 cooperate to clamp and fix the three test tubes, then close the cap 14, and use the buckle lock 34 to connect the cap 14 to the working box 2, and then connect the puncture needle 1 to the connecting hose 15, so that the connecting hose 15 passes through the sleeve 16 and extends to the inside of the cap 14, so that the bottom of the connecting hose 15 The end is aligned with the test tube mouth, and then the patient's lumbar spine is punctured through the puncture needle 1 for sampling, and the internal test tube is observed through the transparent observation plate 30. When the sampling in the test tube is completed, the electric push rod is turned on to drive the top block 17 to move, so that the top block 17 applies pressure to the connecting hose 15 to prevent the sample inside the connecting hose 15 from flowing, and then the second motor 19 is turned on to drive the gear 20 to rotate, so that the gear 20 cooperates with the multiple protrusions 21 to drive the rotating disk 3 to rotate, so as to rotate the test tube on the special-shaped clamping block 6 by 120 degrees, and then the top block 17 is driven by the electric push rod to move, so that the top block 17 is separated from the connecting hose 15, so that another test tube can be sampled and collected.
[0036] The above-mentioned embodiments only express the specific implementation of the present invention, and the description is relatively specific and detailed, but it cannot be understood as limiting the scope of the present invention. The second motor is a stepper motor, and the rotation angle of the stepper motor can be controlled by the existing installation and adjustment methods. At the same time, it should be pointed out that for ordinary technicians in this field, several modifications and improvements can be made without departing from the concept of the present invention, which all belong to the protection scope of the present invention.
Claims
1. A cerebrospinal fluid sampling device for lymphoma detection, comprising a puncture needle (1), characterized in that: The invention also comprises a working box (2), wherein the inner lower side wall of the working box (2) is rotatably connected with a rotating disk (3), the top end of the rotating disk (3) is fixedly connected with a plurality of connecting rods (4), one end of the plurality of connecting rods (4) away from the rotating disk (3) is fixedly connected with a fixed plate (5), and three groups of adjustment mechanisms are installed on the fixed plate (5), wherein the adjustment mechanism comprises a special-shaped clamping block (6), the fixed plate (5) is provided with three first sliding grooves, a first sliding block (7) is slidably connected in the first sliding groove, the top end of the first sliding block (7) is fixedly connected with the special-shaped clamping block (6), the bottom end of the first sliding block (7) is connected with a U-shaped connecting block (9), the top end of the rotating disk (3) is installed with a first motor (10), the output end of the first motor (10) is connected with a screw rod (11), the other end of the screw rod (11) is rotatably connected with the fixed plate (5), an adjustment block (12) is screwed on the screw rod (11), and the adjustment block (12) is rotatably connected with three connecting plates ( 13), the other end of the connecting plate (13) is rotatably connected to the adjusting block (12), the top end of the working box (2) is hingedly connected to a cover cap (14) through a hinge, the cover cap (14) is provided with a through hole extending upward and downward, a connecting hose (15) is arranged in the through hole, the top end of the connecting hose (15) is connected to the puncture needle (1), the top end of the cover cap (14) is fixedly connected to a sleeve (16), the sleeve (16) is communicated with the through hole, and a top is slidably connected in the sleeve (16). A first electric push rod (18) is installed on the sleeve (16), the output end of the first electric push rod (18) passes through the sleeve (16) and is connected to the top block (17), a second motor (19) is installed on the working box (2), the output end of the second motor (19) passes through the working box (2) and is connected to a gear (20), and a top end of the rotating disk (3) is evenly fixedly connected with a plurality of protrusions (21), and the plurality of protrusions (21) are all meshed with the gear (20).
2. A cerebrospinal fluid sampling device for lymphoma detection according to claim 1, characterized in that: Two arc-shaped grooves (22) are provided on each of the three special-shaped clamping blocks (6), and the adjacent arc-shaped grooves (22) on the three special-shaped clamping blocks (6) match each other.
3. A cerebrospinal fluid sampling device for lymphoma detection according to claim 2, characterized in that: The bottom end of the working box (2) is fixedly connected to a base (23), the bottom end of the base (23) is evenly fixedly connected to a plurality of fixing columns (24), the bottom end of the fixing columns (24) is provided with a threaded hole, a threaded rod (25) is threadedly connected in the threaded hole, and the bottom end of the threaded rod (25) is fixedly connected to a support block (26).
4. A cerebrospinal fluid sampling device for lymphoma detection according to claim 3, characterized in that: The bottom ends of the plurality of support blocks (26) are all fixedly connected with a buffer pad (27).
5. A cerebrospinal fluid sampling device for lymphoma detection according to claim 4, characterized in that: The fixing plate (5) is provided with an annular groove (28), a rotating ring (29) is rotatably sleeved on the annular groove (28), and the rotating ring (29) is fixedly connected to the inner wall of the working box (2).
6. A cerebrospinal fluid sampling device for lymphoma detection according to claim 5, characterized in that: The cover cap (14) is provided with a mounting opening, and a transparent observation plate (30) is installed in the mounting opening.
7. A cerebrospinal fluid sampling device for lymphoma detection according to claim 6, characterized in that: The sleeve (16) is provided with a plurality of guide holes, in which guide rods (31) are slidably connected, the guide rods (31) are fixedly connected to the top block (17), and the other ends of the plurality of guide rods (31) are fixedly connected to a limiting plate (32).
8. A cerebrospinal fluid sampling device for lymphoma detection according to claim 7, characterized in that: A handle (33) is fixedly connected to the cover cap (14), and the cover cap (14) is connected to the working box (2) via a buckle lock (34).
9. A cerebrospinal fluid sampling device for lymphoma detection according to claim 8, characterized in that: The fixed plate (5) is provided with six second sliding grooves, in which second sliding blocks (8) are slidably connected, and the six second sliding blocks (8) are respectively fixedly connected to the three special-shaped clamping blocks (6), and the bottom ends of the six second sliding blocks (8) are fixedly connected to the limiting blocks.