Hot compress medicine guiding system and method

Through heat conduction or thermal radiation heating and real-time concentration temperature adjustment, the problems of low drug penetration efficiency and instability in traditional transdermal drug delivery systems are solved, and efficient transdermal drug delivery effect is achieved.

CN119280642APending Publication Date: 2025-01-10YUNNAN PROVINCIAL HOSPITAL OF TRADITIONAL CHINESE MEDICINE
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Patent Information

Application Number
CN202411347572.7
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-09-26
Publication Date
2025-01-10

AI Technical Summary

Technical Problem

In traditional transdermal drug delivery systems, drug penetration efficiency is low and individual differences are large. The heat compress is unstable and uneven, resulting in insufficient drug absorption rate.

Method used

Heat conduction or thermal radiation is used for stable and uniform heating, and the heating temperature is adjusted in real time through the concentration monitoring unit and the control unit to ensure that the drug concentration is within the set range, select suitable heat transfer methods and materials, and combine temperature and concentration monitoring to achieve continuous and effective Heat compress and guide the medicine.

Benefits of technology

It significantly improves the absorption rate of transdermal drug delivery, ensures that the drug concentration is within a safe range, forms a continuous and effective drug delivery closed loop, and improves the therapeutic effect.

✦ Generated by Eureka AI based on patent content.

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Abstract

The invention discloses a hot compress medicine guiding system and method. The method comprises the following steps that S1, the type of a medicine bag is determined; s2, initial parameters are set, specifically, the monitoring range of a concentration monitoring unit and the heating temperature and working time of a heating unit are set according to the medicine bag type determined in S1; s3, selecting a heat transfer mode: determining to use heat conduction or heat radiation to transfer heat based on the wearing position of the medicine bag; and S4, monitoring the drug concentration in real time and adjusting the temperature: continuously monitoring the drug concentration through a concentration monitoring unit, and dynamically adjusting the temperature of a heating unit by a control unit according to a concentration monitoring result so as to maintain the drug concentration within a set range. The device is simple in structure, can continuously act on a drug needing transdermal delivery at a specific temperature for several hours, and automatically adjusts the temperature by identifying the drug concentration, so that the transdermal delivery absorption rate is greatly improved, and a continuous and effective transdermal delivery closed loop is formed.
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Description

Technical Field

[0001] The present invention relates to the technical field of transdermal drug delivery, in particular to a hot compress drug delivery system and method. Background Art

[0002] Transdermal drug delivery system is a method of delivering drugs into the body through the skin. This method avoids the first-pass effect in the liver and gastrointestinal side effects that may be caused by oral administration, while providing continuous and stable drug release. However, traditional transdermal drug delivery systems face the problems of low drug penetration efficiency and large individual differences. Hot compress, as a means of promoting drug penetration, can enhance the transdermal absorption of drugs by dilating blood vessels, increasing skin blood flow and reducing skin resistance.

[0003] Traditional hot compress uses a hot towel or a general heating element to wrap the part to be heated. The towel hot compress heats by thermal convection, which is unstable and uneven, and the heating time is limited. A hot compress drug guide system and method are proposed. Heat can be transferred by heat conduction or thermal radiation to heat stably and evenly, and the heating time can last for several hours, so as to ensure that the transdermal drug delivery absorption rate of the drug package is greatly improved. Summary of the invention

[0004] The object of the present invention is to provide a hot compress medicine guiding system and method to solve the problems raised in the above-mentioned background technology.

[0005] To achieve the above object, the present invention provides the following technical solution: a hot compress medicine guiding method, comprising the following steps:

[0006] S1. Determine the type of medicine package;

[0007] S2. Setting initial parameters: according to the drug package type determined in S1, setting the monitoring range of the concentration monitoring unit, as well as the heating temperature and working time of the heating unit;

[0008] S3. Select the heat transfer method: based on the wearing position of the medicine pack, decide whether to use heat conduction or heat radiation to transfer heat;

[0009] S4. Real-time monitoring of drug concentration and temperature adjustment: The drug concentration is continuously monitored by the concentration monitoring unit, and the control unit dynamically adjusts the temperature of the heating unit according to the concentration monitoring result to maintain the drug concentration within the set range.

[0010] As a further solution of the present invention: the specific steps of step 3 are as follows:

[0011] S3.1. When the heating unit is in direct contact with the medicine package, heat is directly transferred from the heating unit to the medicine package by heat conduction;

[0012] S3.2 When the heating unit and the medicine package are not in direct contact, heat is transferred from the heating unit to the medicine package by thermal radiation.

[0013] As a further solution of the present invention: the specific steps in step 4 are as follows:

[0014] S4.1. Select two specific values ​​within the drug package concentration monitoring range as trigger points for controlling the heating unit, which are defined as a first set value and a second set value: the first set value represents a higher concentration threshold, and the second set value represents a lower concentration threshold;

[0015] S4.2, when it is detected that the concentration of the drug package reaches or exceeds the first set value, the heating unit stops heating and enters the insulation mode to keep the concentration of the drug package stable within the set range to avoid abnormal concentration increase caused by overheating;

[0016] S4.3. When it is detected that the concentration of the medicine package is lower than the second set value: start the heating unit to increase the temperature of the medicine package to make the concentration return to the set safety range.

[0017] A hot compress medicine guiding system comprises a control unit and a heating unit controlled by the control unit, wherein the control unit monitors the temperature of a medicine package through a temperature monitoring unit, and the control unit monitors the medicine concentration of the medicine package through a concentration monitoring unit, and is configured to adjust the heating temperature in real time under different medicine concentration requirements.

[0018] As a further solution of the present invention: the control unit includes a temperature control module, an overheat protection module and a timing shutdown module, and the temperature control module, the overheat protection module and the timing shutdown module are all connected to the heating unit.

[0019] As a further solution of the present invention: the temperature monitoring unit is composed of a temperature sensor, and the temperature sensor is connected to the control unit.

[0020] Compared with the prior art, the present invention has the following beneficial effects:

[0021] The present application can continuously act on drugs that require transdermal administration at a specific temperature for several hours, and automatically adjust the temperature by identifying the drug concentration, thereby greatly improving the absorption rate of transdermal administration and forming a continuous and effective transdermal administration closed loop. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] Figure 1 This is a schematic diagram of the principle of the hot compress medicine guiding system of the present invention;

[0023] Figure 2 It is a schematic diagram of the principles of the control unit and the heating unit of the present invention;

[0024] In the figure: 1. control unit; 2. heating unit; 3. temperature monitoring unit; 4. concentration monitoring unit; 5. medicine package. DETAILED DESCRIPTION

[0025] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0026] See also Figure 1 In an embodiment of the present invention, a hot compress medicine guiding method comprises the following steps:

[0027] S1, determine the type of medicine package 5;

[0028] S2, setting initial parameters: according to the type of drug package 5 determined in S1, setting the monitoring range of the concentration monitoring unit 4, and the heating temperature and working time of the heating unit 2;

[0029] S3, select a heat transfer method: based on the wearing position of the medicine package 5, decide to use heat conduction or heat radiation to transfer heat, so as to ensure that the selected heat transfer method can continuously maintain the heat of the medicine package 5 without being affected by other factors;

[0030] The specific steps of step 3 are as follows:

[0031] S3.1, when the heating unit 2 is in direct contact with the medicine package 5, heat is directly transferred from the heating unit 2 to the medicine package 5 by heat conduction;

[0032] S3.2 When the heating unit 2 and the medicine package 5 are not in direct contact, heat is transferred from the heating unit 2 to the medicine package 5 by thermal radiation.

[0033] S4. Real-time monitoring of drug concentration and temperature adjustment: The drug concentration is continuously monitored by the concentration monitoring unit 4, and the control unit 1 dynamically adjusts the temperature of the heating unit 2 according to the concentration monitoring result to maintain the drug concentration within the set range.

[0034] S4.1. Select two specific values ​​within the concentration monitoring range of the drug package 5 as trigger points for controlling the heating unit 2, which are defined as a first set value and a second set value: the first set value represents a higher concentration threshold, and the second set value represents a lower concentration threshold;

[0035] S4.2, when it is detected that the concentration of the medicine package 5 reaches or exceeds the first set value, the heating unit 2 stops heating and enters the heat preservation mode to keep the concentration of the medicine package 5 stable within the set range to avoid abnormal concentration increase caused by overheating;

[0036] S4.3, when it is detected that the concentration of the medicine package 5 is lower than the second set value: start the heating unit 2 to increase the temperature of the medicine package 5 to promote the concentration to return to the set safety range.

[0037] A hot compress medicine guiding system comprises a control unit 1 and a heating unit 2 controlled by the control unit 1, wherein the control unit 1 monitors the temperature of a medicine package 5 via a temperature monitoring unit 3, and the control unit 1 monitors the medicine concentration of the medicine package 5 via a concentration monitoring unit 4, and is configured to adjust the heating temperature in real time under different drug concentration requirements.

[0038] Specifically, the device transfers heat by heat conduction or heat radiation by selecting and using materials with excellent electrical and thermal conductivity; the control unit is used to adjust the temperature and working time of the heating unit; the drug concentration monitoring unit is used to monitor the concentration of drugs to be absorbed transdermally, and the monitoring device sets a value of 0-100 to monitor the drug concentration in real time; for example, a medicine package for treating knee pain, the drug concentration needs to be maintained at about 80 to meet the needs of continuous hot compress and drug conduction for 4 hours, and the effect is the best. Initially, the drug package 5 is heated by the heating unit 2, and the drug concentration monitoring unit 4 monitors in real time. When the drug concentration reaches 80, the heating unit 2 stops heating and enters the insulation state. When the concentration monitoring unit 4 monitors the concentration to be lower than about 70, the heating unit 2 starts heating to form a closed loop, which greatly improves the absorption rate of transdermal drug delivery and significantly improves the treatment effect.

[0039] See also Figure 2 In one embodiment, in this embodiment, preferably, the control unit 1 includes a temperature control module, an overheating protection module and a timing shutdown module, and the temperature control module, the overheating protection module and the timing shutdown module are all connected to the heating unit 2.

[0040] Specifically, the overheat protection module and the timed shutdown module enable the system to have overheat protection and timed shutdown functions to prevent burns and overheating, and the temperature control module can control the heating unit 2. The heating unit 2 can use PI heating film, graphene, carbon fiber heating element or iron powder and other materials with good electrical and thermal conductivity, and generate heat through electric current heating. On the one hand, the temperature control of the medicine package 5 is more accurate, and on the other hand, it is low in cost and simple to operate. The control unit 1 monitors the temperature of the heating unit through a temperature sensor, and adjusts the heating power through a microprocessor to maintain the set treatment temperature. In addition, the device can be used for the knees, neck, shoulders, hands, elbows, waist, spine, feet, abdomen and other positions, and the design should conform to ergonomic principles to ensure wearing comfort and convenience.

[0041] See also Figure 1 In one embodiment, in this embodiment, preferably, the temperature monitoring unit is composed of a temperature sensor, and the temperature sensor is connected to the control unit. Further, the heating power is adjusted by a microprocessor to maintain the set treatment temperature.

[0042] Although this specification is described according to implementation modes, not every implementation mode includes only one independent technical solution. This description of the specification is only for the sake of clarity. Those skilled in the art should regard the specification as a whole. The technical solutions in each embodiment may also be appropriately combined to form other implementation modes that can be understood by those skilled in the art.

[0043] Therefore, the above description is only a preferred embodiment of the present application and is not intended to limit the scope of implementation of the present application; that is, all equivalent changes made according to the scope of the claims of the present application are within the protection scope of the claims of the present application.

Claims

1. A hot compress medicine guiding method, characterized in that: The following steps are involved: S1. Determine the type of medicine package; S2. Setting initial parameters: according to the drug package type determined in S1, setting the monitoring range of the concentration monitoring unit, as well as the heating temperature and working time of the heating unit; S3. Select the heat transfer method: based on the wearing position of the medicine pack, decide whether to use heat conduction or heat radiation to transfer heat; S4. Real-time monitoring of drug concentration and temperature adjustment: The drug concentration is continuously monitored by the concentration monitoring unit, and the control unit dynamically adjusts the temperature of the heating unit according to the concentration monitoring result to maintain the drug concentration within the set range.

2. The hot compress medicine guiding method according to claim 1, characterized in that: The specific steps of step 3 are as follows: S3.

1. When the heating unit is in direct contact with the medicine package, heat is directly transferred from the heating unit to the medicine package by heat conduction; S3.2 When the heating unit and the medicine package are not in direct contact, heat is transferred from the heating unit to the medicine package by thermal radiation.

3. The hot compress medicine guiding method according to claim 1, characterized in that: The specific steps in step 4 are as follows: S4.

1. Select two specific values ​​within the drug package concentration monitoring range as trigger points for controlling the heating unit, which are defined as a first set value and a second set value: the first set value represents a higher concentration threshold, and the second set value represents a lower concentration threshold; S4.2, when it is detected that the concentration of the drug package reaches or exceeds the first set value, the heating unit stops heating and enters the insulation mode to keep the concentration of the drug package stable within the set range to avoid abnormal concentration increase caused by overheating; S4.

3. When it is detected that the concentration of the medicine package is lower than the second set value: start the heating unit to increase the temperature of the medicine package to make the concentration return to the set safety range.

4. A hot compress medicine delivery system using the method according to any one of claims 1 to 3, characterized in that: It includes a control unit and a heating unit controlled by the control unit. The control unit monitors the temperature of the medicine package through a temperature monitoring unit, and the control unit monitors the drug concentration of the medicine package through a concentration monitoring unit. The control unit is configured to adjust the heating temperature in real time under different drug concentration requirements.

5. The hot compress medicine guiding system according to claim 4, characterized in that: The control unit comprises a temperature control module, an overheat protection module and a timing shutdown module, and the temperature control module, the overheat protection module and the timing shutdown module are all connected to the heating unit.

6. The hot compress medicine guiding system according to claim 4, characterized in that: The temperature monitoring unit is composed of a temperature sensor, and the temperature sensor is connected to the control unit.