High-pressure-resistant immobilized continuous production equipment with adjustable filling height

Abstract

The invention discloses high-pressure-resistant immobilized continuous production equipment with adjustable filling height. The high-pressure-resistant immobilized continuous production equipment comprises a reaction chamber, a solid carrier filler feeder, a bottom solid carrier baffle, a bottom high-pressure sealing ring, a bottom fixing part, a top solid carrier baffle, a top high-pressure sealing ring, a top fixing part, temperature detection equipment and an external heating device. The problems that the filler height of a traditional immobilized reactor cannot be adjusted at will, and solid carrier filler filling is tedious can be solved; the problem of non-uniform filling of solid objects is solved; the problem of high pressure resistance of the immobilized reactor is solved; the problem of immobilization of the immobilized filler in the reactor is solved, so that reactants can enter the reactor from bottom to top; the design structure is optimized, pipeline connection penetrating through the heat exchange layer and the reactor is avoided, and the safety problem is solved; the maximization of the use of the immobilized reactor is realized, and the consumption of manpower and material resources is reduced.

Description

Technical Field

[0001] The invention belongs to the technical field of chemical industry and pharmaceutical industry, and in particular relates to a high-pressure resistant and continuous production solid-load reactor, and specifically relates to a high-pressure resistant solid-load continuous production device with adjustable filling height. Background Art

[0002] In the continuous chemical manufacturing process, common types of immobilized reactions include enzyme immobilized reactions, acid immobilized reactions, and catalyst immobilized reactions. These reactions require filling and replacing the immobilized materials, and ensuring that the immobilized materials are immobilized to promote uniform contact with the reaction liquid. Some reactions may involve violent heat release, high temperature and pressure, or gas-liquid two-phase, which requires the immobilized reactor to have good heat transfer, pressure resistance, and corrosion resistance.

[0003] The solid-loaded reactors commonly used in industry are mainly divided into two types: 1. Low-pressure bottom-in and top-out spiral pressure-loaded reactor; 2. High-pressure top-in and bottom-out filling pressure-loaded reactor. However, both types of solid-loaded reactors have their inevitable disadvantages.

[0004] Attached Figure 1 The figure shows a partial view of a low-pressure bottom-in and top-out spiral pressure solid-loaded reactor, in which the temperature display 81, solid load inlet 82, heat exchange jacket 83, material outlet 84, filter head 85, heat exchange liquid outlet 86, solid load filler 87, lifting screw 88, pressure material rotating handshake 89 and other components are marked. The disadvantage of this solid-loaded reactor is that it relies solely on the contact and seal between the filter head 85 and the inside of the cavity, which is not resistant to high pressure. In addition, the filter head 85 moves up and down with the pressure material rotating handshake 89, causing the filter head 85 and the sealing ring inside the cavity to be scratched, resulting in airtight leakage. At the same time, the thermometer needs to pass through the heat exchange jacket 83 to contact the solid load filler 87. If the connection is not handled properly, the joint buried in the heat exchange liquid will leak, which will cause pollution and danger.

[0005] Attached Figure 2 The figure shows a schematic diagram of the local structure of a high-pressure top-in and bottom-out filling-type pressurized solid-loaded reactor, in which components such as a temperature display 91, a solid-loaded material inlet 92, a heat exchange jacket 93, a material inlet 94, a pressurized material 95, a heat exchange liquid outlet 96, and a solid-loaded material filler 97 are marked. The disadvantage of this solid-loaded reactor is that the material can only be in the form of top-in and bottom-out. If the material is in the form of bottom-in and top-out, the solid-loaded material filler 97 will move and run away. In addition, the material cannot fill the entire reaction column with top-in and bottom-out, which reduces the contact time between the material and the solid-loaded material. Summary of the invention

[0006] In view of the fact that the solid-loaded reactor in the prior art cannot simultaneously meet the requirements of high pressure resistance, material inlet and outlet, and equipment matching requirements for different filling heights, the present invention provides a high-pressure resistant solid-loaded continuous production equipment with adjustable filling height. The specific technical solution adopted by the present invention is as follows:

[0007] A high-pressure resistant solid continuous production equipment with adjustable filling height, characterized in that it comprises a reaction chamber, a solid filler feeder, a bottom solid baffle, a bottom high-pressure sealing ring, a bottom fixing component, a top solid baffle, a top high-pressure sealing ring, a top fixing component, a temperature detection device, and an external heating device;

[0008] The end of the solid filler feeder is communicated with the wall of the reaction chamber, and the solid filler enters the reaction chamber through the solid filler feeder;

[0009] The bottom solid load baffle is installed on the bottom of the equipment by the bottom fixing component, and the bottom solid load baffle supports the solid load filler;

[0010] The top solid carrier baffle is installed on the top of the device by the top fixing component; the bottom solid carrier baffle, the top solid carrier baffle and the reaction chamber form a closed space;

[0011] The temperature detection device comprises a temperature detector and a temperature sleeve, wherein the detection head of the temperature detector is located between the top solid support baffle and the bottom solid support baffle in the reaction chamber;

[0012] The reaction chamber is also provided with a material inlet and a material outlet. The material inlet is arranged at the lower end of the reaction chamber, and the material outlet is arranged at the upper end of the reaction chamber.

[0013] In some specific embodiments, the cross section of the bottom solid support baffle is annular, a filter screen is provided inside the bottom solid support baffle, and the bottom tip of the bottom solid support baffle is through and connected to the solid support filler outlet pipe to form a solid support filler outlet.

[0014] In some specific embodiments, the bottom fixing component includes a bottom flange, a flange fixing hoop, a flange fixing cover, and a bottom ferrule; the bottom flange includes a bottom upper flange and a bottom lower flange, which are captured by the flange fixing hoop and the flange fixing cover; the bottom ferrule fixes the bottom lower flange to the solid load filler outlet pipe.

[0015] In some specific embodiments, the cross section of the top solid load baffle is annular, a filter screen is provided inside the top solid load baffle, and the top tip of the top solid load baffle is through and connected to the temperature sleeve to form a passage for the temperature probe to pass through.

[0016] In some specific embodiments, the top fixing component includes a top flange, a flange fixing hoop, a flange fixing cover, a first high-pressure ferrule, a second high-pressure ferrule, and a lifting screw; the top flange includes a top upper flange and a top lower flange, which are captured by the flange fixing hoop and the flange fixing cover; the first high-pressure ferrule fixes the top upper flange to the temperature sleeve, and the second high-pressure ferrule fixes the lifting screw to the temperature sleeve.

[0017] In some specific embodiments, the external heating device is a heat exchange jacket, the heat exchange liquid inlet is arranged below the heat exchange jacket, and the heat exchange liquid outlet is arranged above the heat exchange jacket.

[0018] In some specific embodiments, a heat-insulating layer is further disposed outside the external heating device.

[0019] In some specific embodiments, a sealing opening is provided at the lower end of the reaction chamber near the bottom solid support baffle, and the sealing opening is stepped and used for accommodating the bottom high-pressure sealing ring.

[0020] In some specific embodiments, the temperature detection device also includes a temperature display.

[0021] In some specific embodiments, a plurality of the devices are connected in series in sequence through a pipeline, and the material outlet of the front-end device is connected to the material inlet of the back-end device through the pipeline.

[0022] Compared with the prior art, the present invention has the following beneficial effects:

[0023] Solve the problem that traditional solid-loaded reactors cannot simultaneously meet the requirements of high pressure resistance and bottom-in and top-out; solve the problem that the height of the solid-loaded filler cannot be adjusted arbitrarily and the loading of the solid-loaded filler is cumbersome; maximize the use of the solid-loaded reactor and reduce the consumption of manpower and material resources.

[0024] The concept, specific structure and technical effects of the present invention will be further described below in conjunction with the accompanying drawings to fully understand the purpose, characteristics and effects of the present invention. BRIEF DESCRIPTION OF THE DRAWINGS

[0025] Figure 1 It is a schematic diagram of the partial structure of a low-pressure bottom-in and top-out spiral pressure-pressed solid-loaded reactor.

[0026] Figure 2 It is a schematic diagram of the partial structure of a high-pressure top-in and bottom-out filling type pressurized solid-loaded reactor.

[0027] Figure 3 It is a schematic diagram of the structure of the solid-supported reactor of the present invention.

[0028] Figure 4The bottom structure diagram of the solid-supported reactor of the present invention is shown in FIG. 1 , wherein (a) is a schematic diagram of the structure before assembly, and (b) is a schematic diagram of the structure after assembly.

[0029] Figure 5 The following are partial structural diagrams of the bottom solid load baffle of the present invention. (a) is a structural diagram of the bottom solid load baffle being fixed to the bottom lower flange; (b) is a structural diagram of the bottom solid load baffle and the high-pressure sealing ring.

[0030] Figure 6 Schematic diagram of the top structure of the solid support reactor of the present invention. (a) is a schematic diagram of the structure when the support filler is reinforced; (b) is a schematic diagram of the structure after the support filler is reinforced.

[0031] Figure 7 The schematic diagram of the local structure of the top solid load baffle of the present invention is shown in Figure 1. (a) is a schematic diagram of the structure of the top solid load baffle and the temperature sleeve; (b) is a schematic diagram of the structure of the top solid load baffle and the high-pressure sealing ring.

[0032] Figure 8 It is a schematic diagram of the internal structure of the high-pressure ferrule of the present invention.

[0033] Fig. 9 It is a schematic diagram of the serial use of multiple solid-supported reactors of the present invention.

[0034] Description of the markings in the figure:

[0035] 1. Solid load filler inlet; 2. Insulation layer; 3. Heat exchange jacket; 4. Temperature sleeve; 5. Solid load filler; 6. Bottom solid load baffle; 7. Solid load filler outlet; 8. Temperature display; 9. Lifting filter head; 10. Top flange connection; 11. Material outlet; 12. Heat exchange liquid outlet; 13. Heat exchange liquid inlet; 14. Material inlet; 15. Bottom flange connection; 16. Top solid load baffle.

[0036] 21. Sealing port; 22. High-pressure sealing ring; 23. Flange fixing cover; 24. Half-moon flange fixing hoop; 25. Solid load filler outlet; 26. Filter screen; 27. Bottom lower flange; 28. Bottom ferrule.

[0037] 31. Lifting screw; 32. Solid filler feeder; 33. High-pressure ferrule.

[0038] 41. Compression fitting; 42. High-pressure sealing ring; 43. Filter; 44. Straight-through part of casing.

[0039] 51. High-pressure front ferrule; 52. High-pressure rear ferrule; 53. High-pressure ferrule cap.

[0040] 81. Temperature display; 82. Solid load inlet; 83. Heat exchange jacket; 84. Material outlet; 85. Filter head; 86. Heat exchange liquid outlet; 87. Solid filler; 88. Lifting screw; 89. Pressing and rotating handshake.

[0041] 91. Temperature display; 92. Solid load inlet; 93. Heat exchange jacket; 94. Material inlet; 95. Filling press; 96. Heat exchange liquid outlet; 97. Solid load filler. DETAILED DESCRIPTION

[0042] In order to make the technical means, creative features, objectives and effects of the invention easier to understand, the invention is further described below with reference to specific diagrams. However, the invention is not limited to the following implementation cases.

[0043] It should be noted that the structures, proportions, sizes, etc. illustrated in the drawings in this specification are only used to match the contents disclosed in the specification so as to facilitate understanding and reading by persons familiar with this technology. They are not used to limit the conditions under which the present invention can be implemented, and therefore have no substantive technical significance. Any structural modification, change in proportion or adjustment of size, without affecting the effects and purposes that can be achieved by the present invention, should still fall within the scope of the technical contents disclosed by the present invention.

[0044] Example 1

[0045] Figure 3 Schematic diagram of the structure of the solid-loaded reactor of the present invention, in which are marked a solid-loaded filler inlet 1, a thermal insulation layer 2, a heat exchange jacket 3, a temperature sleeve 4, a solid-loaded filler 5, a bottom solid-loaded baffle 6, a solid-loaded filler outlet 7, a temperature display 8, a lifting filter head 9, a top flange connection 10, a material outlet 11, a heat exchange liquid outlet 12, a heat exchange liquid inlet 13, a material inlet 14, a bottom flange connection 15, and a top solid-loaded baffle 16.

[0046] The solid filler 5 enters the reaction chamber through the solid filler inlet 1. A bottom solid filler baffle 6 is provided at the bottom of the reaction chamber for receiving the solid filler 5. A top solid filler baffle 16 is provided at the top of the reaction chamber. In the working state, the solid filler 5 is located between the top solid filler baffle 16 and the bottom solid filler baffle 6, and the upper and lower ends of the solid filler 5 are in close contact with the top solid filler baffle 16 and the bottom solid filler baffle 6, respectively.

[0047] like Figure 4 , Figure 5As shown, the cross section of the bottom solid carrier baffle 6 is annular, and in the working state, it is in close contact with the annular high-pressure sealing ring 22 to form a good airtightness. A filter screen 26 is provided in the bottom solid carrier baffle 6. When the reaction material enters from the bottom and exits from the top, it can flow through the filter screen 26 and then flow through the solid carrier filler 5. The bottom tip of the bottom solid carrier baffle 6 is penetrated and connected to the solid carrier filler outlet pipe to form a solid carrier filler outlet 7. Before the reaction, the bottom solid carrier baffle 6 is adjusted to a suitable position, for example, after its upper end is in close contact with the high-pressure sealing ring 22 placed at the sealing port 21, the bottom lower flange 27 is pushed to a position close to the bottom upper flange, and the bottom lower flange 27 is fixed to the solid carrier filler outlet pipe by the bottom clamp 28, and then the flange device is locked, so that the position of the bottom solid carrier baffle 6 can be fixed.

[0048] like Figure 6 , Figure 7 As shown, the cross section of the top solid baffle 16 is annular, and in the working state, it is in close contact with the annular high-pressure sealing ring 42 to form a good airtightness. A filter screen 43 is provided in the top solid baffle 16. When the reaction material enters from the bottom and exits from the top, it can flow through the solid filler 5 and then through the filter screen 43. The top tip of the top solid baffle 16 is penetrated and connected to the temperature sleeve 4 to form a passage for the temperature detector to pass through. Before the reaction, the solid filler is first added to the reaction chamber, and then the top solid baffle 16 is adjusted to a suitable position and locked, for example, the top solid baffle 16 is naturally dropped to the top of the solid filler 5 and then locked in position.

[0049] The temperature detector is connected to the external temperature display 8, so that the temperature in the reaction chamber can be quickly displayed on the temperature display 8. A heat exchange jacket 3 is provided on the outside of the reaction chamber for passing the heat exchange liquid, thereby changing the temperature in the reaction chamber. An insulation layer 2 is also provided on the outside of the heat exchange jacket 3 for maintaining the temperature of the heat exchange liquid and reducing the heat energy loss of the heat exchange liquid. The reaction material enters the reaction chamber from the material inlet 14, and then passes through the filter screen 26 in the bottom solid support baffle 6, and is fully in contact with the solid support filler 5 filled in the reaction chamber. Afterwards, the reaction material passes through the filter screen 43 in the top solid support baffle 16, and leaves the solid support reactor through the material outlet 11, forming a material flow from bottom to top. At the same time, the heat exchange liquid enters the heat exchange jacket 3 from the heat exchange liquid inlet 13, and leaves the solid support reactor through the heat exchange liquid outlet 12. Since the entire reaction chamber remains in a closed state, the system can be maintained in a high pressure state.

[0050] Example 2

[0051] Figure 4 is a schematic diagram of the bottom structure of the solid-supported reactor of the present invention, Figure 5 It is a schematic diagram of the local structure of the bottom solid load baffle of the present invention.

[0052] Before the reaction starts, first place the high-pressure sealing ring 22 on the step of the sealing port 21, and place the bottom solid load baffle 6 close to the high-pressure sealing ring 22. Clamp the bottom upper and lower flanges through the half-moon flange fixing hoop 24, and lock the bottom solid load baffle 6 with the bottom lower flange 27 through the bottom clamp 28. Cover the annular flange fixing cover 23 on the double half-moon flange fixing hoop 24 to prevent the double half-moon flange fixing hoop 24 from being separated from the left and right. Lock the screw on the double half-moon flange fixing hoop 24 to lock the upper and lower flanges; lock the screw on the annular flange fixing cover 23 to connect it with the double half-moon flange fixing hoop 24.

[0053] Example 3

[0054] Figure 6 is a schematic diagram of the top structure of the solid-supported reactor of the present invention, Figure 7 It is a schematic diagram of the local structure of the top solid load baffle of the present invention.

[0055] Before reinforcing the solid filler, first loosen the two high-pressure ferrules 33, then adjust the lifting screw 31 to raise the top solid baffle 16 to the upper end of the solid feed port, open the valve of the solid filler feeder 32, and add the solid filler to the reactor. After the filling is completed, adjust the lifting screw 31 so that the top solid baffle 16 naturally falls to the top of the solid filler 5. Lock the fixing bolts on the lifting screw 31 so that it is connected to the reactor itself to achieve the purpose of locking. Then lock the high-pressure ferrule 33 to achieve the purpose of high-pressure sealing.

[0056] Figure 7 A ferrule joint 41 is fixed on the temperature sleeve 4 in (a), and the ferrule joint 41 is connected to the lower component in the figure by using existing technology such as threading.

[0057] Figure 8 The schematic diagram of the internal structure of the high-pressure ferrule is shown, including a high-pressure sealing ring 22, a high-pressure front ferrule 51, a high-pressure rear ferrule 52, and a high-pressure ferrule cap 53. During operation, the above components are tightly connected, the high-pressure sealing ring 22 is placed on the high-pressure front ferrule 51, the high-pressure front ferrule 51 and the high-pressure rear ferrule 52 are tightly matched together, the high-pressure ferrule cap 53 tightly buckles the high-pressure front ferrule 51 and the high-pressure rear ferrule 52, and the temperature sleeve 4 passes through the middle of the above components.

[0058] Example 4

[0059] In some cases, multiple solid-supported reactors can be used in series, such as Fig. 9 As shown, the material outlet of the front-end device is connected to the material inlet of the back-end device through a pipeline, and a suitable number of solid-loaded reactors are used as needed to achieve the purpose of expanding production capacity.

[0060] The present invention designs a high-pressure resistant solid-load continuous production equipment with easy replacement of solid fillers, reasonable design position of temperature probe, and arbitrary filling height that allows materials to enter and exit from the bottom, thereby maximizing the use of solid-load equipment, improving equipment utilization, reducing the use of solid-load fillers, and reducing the consumption of manpower and material resources. The present invention can solve the problem that the filling height of traditional solid-load reactors cannot be arbitrarily adjusted and the loading of solid-load fillers is cumbersome; solve the problem of uneven solid-load filling; solve the problem of high-pressure resistance of solid-load reactors; solve the problem of fixing solid-load fillers in the reactor, so that reactants can enter and exit the reactor from the bottom; optimize the design structure, eliminate the pipe connection that runs through the heat exchange layer and the reactor, and solve the safety problem; maximize the use of solid-load reactors and reduce the consumption of manpower and material resources.

[0061] The preferred specific embodiments of the present invention are described in detail above. It should be understood that ordinary technicians in the field can make many modifications and changes based on the concept of the present invention without creative work. Therefore, all technical solutions that can be obtained by technicians in the technical field based on the concept of the present invention through logical analysis, reasoning or limited experiments on the basis of the prior art should be within the scope of protection determined by the claims.

Claims

1. A high pressure resistant solid load continuous production equipment with adjustable filling height, characterized in that: It includes a reaction chamber, a solid material filler feeder, a bottom solid material baffle, a bottom high-pressure sealing ring, a bottom fixing component, a top solid material baffle, a top high-pressure sealing ring, a top fixing component, a temperature detection device, and an external heating device; The end of the solid filler feeder is communicated with the wall of the reaction chamber, and the solid filler enters the reaction chamber through the solid filler feeder; The bottom solid load baffle is installed on the bottom of the equipment by the bottom fixing component, and the bottom solid load baffle supports the solid load filler; The top solid carrier baffle is installed on the top of the device by the top fixing component; the bottom solid carrier baffle, the top solid carrier baffle and the reaction chamber form a closed space; The temperature detection device comprises a temperature detector and a temperature sleeve, wherein the detection head of the temperature detector is located between the top solid support baffle and the bottom solid support baffle in the reaction chamber; The reaction chamber is also provided with a material inlet and a material outlet. The material inlet is arranged at the lower end of the reaction chamber, and the material outlet is arranged at the upper end of the reaction chamber.

2. The high pressure resistant solid load continuous production equipment with adjustable filling height according to claim 1 is characterized in that: The cross section of the bottom solid load baffle is annular, a filter screen is arranged inside the bottom solid load baffle, and the bottom tip of the bottom solid load baffle is through and connected to the solid load filler outlet pipe to form a solid load filler outlet.

3. The high pressure resistant solid load continuous production equipment with adjustable filling height according to claim 2 is characterized in that: The bottom fixing component includes a bottom flange, a flange fixing hoop, a flange fixing cover, and a bottom ferrule; the bottom flange includes a bottom upper flange and a bottom lower flange, which are restrained by the flange fixing hoop and the flange fixing cover; the bottom ferrule fixes the bottom lower flange to the solid load filler outlet pipe.

4. The high pressure resistant solid load continuous production equipment with adjustable filling height according to claim 1, characterized in that: The cross section of the top solid load baffle is annular, a filter screen is arranged inside the top solid load baffle, and the top tip of the top solid load baffle is penetrated and connected with the temperature sleeve to form a passage for the temperature detector to pass through.

5. The high pressure resistant solid load continuous production equipment with adjustable filling height according to claim 4, characterized in that: The top fixing component includes a top flange, a flange fixing hoop, a flange fixing cover, a first high-pressure ferrule, a second high-pressure ferrule, and a lifting screw; the top flange includes a top upper flange and a top lower flange, which are restrained by the flange fixing hoop and the flange fixing cover; the first high-pressure ferrule fixes the top upper flange to the temperature sleeve, and the second high-pressure ferrule fixes the lifting screw to the temperature sleeve.

6. The high pressure resistant solid load continuous production equipment with adjustable filling height according to claim 1, characterized in that: The external heating device is a heat exchange jacket, the heat exchange liquid inlet is arranged below the heat exchange jacket, and the heat exchange liquid outlet is arranged above the heat exchange jacket.

7. The high pressure resistant solid load continuous production equipment with adjustable filling height according to any one of claims 1 or 6, characterized in that: A heat preservation layer is also arranged outside the external heating device.

8. The high pressure resistant solid load continuous production equipment with adjustable filling height according to claim 1, characterized in that: A sealing opening is provided at the lower end of the reaction chamber near the bottom solid carrier baffle, and the sealing opening is step-shaped and is used for placing the bottom high-pressure sealing ring.

9. The high pressure resistant solid load continuous production equipment with adjustable filling height according to claim 1, characterized in that: The temperature detection device also includes a temperature display.

10. The high pressure resistant solid load continuous production equipment with adjustable filling height according to claim 1, characterized in that: The plurality of devices are connected in series in sequence through pipelines, and the material outlet of the front-end device is connected to the material inlet of the back-end device through the pipeline.

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