Multi-cell assembly installation auxiliary equipment for repairing endometrial injury

Abstract

The invention discloses multi-cell assembly installation auxiliary equipment for repairing endometrial injury, and belongs to the technical field of medical auxiliary equipment. A multicellular assembly installation auxiliary device for repairing endometrial injury comprises an auxiliary device body. According to the multi-cell assembly installation auxiliary equipment for repairing endometrial injury, a cutting knife is adopted to cut various gel cell carriers into a layer of thin sheets and wind the thin sheets on the surface of a thin film of a reel, a plurality of sliding blocks move in opposite directions in a sliding groove, the gel cell carrier thin sheets wound on the surface of the thin film are flatly spread on the surface of a bottom film, and therefore the gel cell carriers can be fixed. According to the stacking sequence designed by an operator, the gel cell carriers are sequentially and neatly stacked up and down, so that the assembly dislocation of the gel cell carriers is prevented, the regularity and stability of the shape and the structure of the assembled cell carriers are ensured, and the gel cell carrier sheets are prevented from being damaged in the transfer and assembly process; and the effectiveness of subsequent transplantation operation in the uterine cavity of the human body and repair of endometrial injury is ensured.

Description

Technical Field

[0001] The present invention relates to the technical field of medical auxiliary equipment, and more specifically to a multi-cell assembly installation auxiliary equipment for repairing endometrial damage. Background Art

[0002] Multicellular assemblies are organoids with spatial organizational structures that are formed by assembling multiple cell types using cell carriers. They are closer to real human tissues in structure and function, and can be used as a research model to replace in vivo experiments to conduct in vitro functional research on human cells or tissues, which helps researchers to have a deeper understanding of tissue function. More importantly, the produced multicellular assemblies can be used in clinical tissue transplantation and injury repair treatment. Multicellular assemblies are three-dimensional, multi-layered, tissue-engineered structures with complex preparation and assembly processes. Therefore, it is necessary to design a multicellular assembly installation auxiliary device that can also realize preparation and assembly automation to improve operational efficiency.

[0003] Before the multi-cellular assembly is stacked and assembled, the cells need to be cultured in an existing incubator. After the cells are cultured in the incubator, the gel is added and mixed, and after a period of culture, it solidifies to form a cell carrier. When assembling a multi-cellular assembly, it is usually necessary to first mix and culture the first layer of cells and gel in a culture dish. After solidification, the second layer of cells and gel are mixed and added to the first layer, and the same process is repeated to assemble the next layer of cell carriers. However, the surfaces of different layers of cell carriers are irregular, the combination is unstable, and the shape and size of the assembly are uncontrolled. Different cell carriers can also be prepared separately, and then a push plate or tweezers are used to clamp and transfer the cell carriers for stacking and installation. However, the above-mentioned laboratory operations can only use traditional laboratory cell culture equipment, and there is no dedicated equipment that matches the assembly operation, which seriously affects the assembly process. In addition, the assembly time is long, which may affect cell activity and multi-layer cell carriers. During the stacking assembly process, traditional equipment clamping or transfer cannot guarantee the stability of the shape and structure of the assembled cell carrier, as well as the flexibility of operation. In particular, each layer of the cell carrier is relatively thin, and tweezers are used to clamp it during the assembly process. The surface integrity of each layer of the cell carrier is easily damaged. If the position of each layer of the cell carrier is tilted or offset during assembly and movement, the cell carrier assembly will be misaligned, affecting the accuracy of endometrial assembly. Currently, there is no equipment specifically used to assist in the installation of endometrial assemblies, and it can only be performed manually in the laboratory. The operation is cumbersome and rough, and the shape and structure of the assembled cell carriers are irregular, affecting the subsequent human intrauterine transplantation operation and the effectiveness of repairing endometrial damage. Summary of the invention

[0004] The purpose of the present invention is to provide a multi-cell assembly installation auxiliary device for repairing endometrial damage to solve the problems raised in the above background technology:

[0005] In order to achieve the above object, the present invention provides the following technical solutions:

[0006] A multi-cell assembly installation auxiliary device for repairing endometrial damage comprises an auxiliary device body, a workbench is fixedly installed on the top surface of the auxiliary device body, a bracket is fixedly installed on one end surface of the workbench, a slide groove is provided on the inner side surface of the bracket, a plurality of matching sliders are slidably connected inside the slide groove, a cutting knife is fixedly installed on the surface of any one of the sliders, a reel is rotatably connected to the surface of any one of the sliders, the reel is located on one side of the cutting knife, a film is fixedly coated on the surface of the reel, a first gear is coaxially fixedly installed on the surface of the reel, an incubator with the same number as the sliders is fixedly connected to the surface of the workbench, and the incubator has a plurality of sliders inside. The support is slidably connected to a culture dish matching it, a first tooth plate meshing with the first gear is fixedly installed on the inner side surface of the support, the first tooth plate is the same as the number of culture boxes, and the first tooth plate corresponds to the position of the culture boxes, a cutting table is fixedly installed on the surface of the workbench, the cutting table is located on one side of the culture box, the surface of the cutting table is provided with a paved bottom film, any of the culture boxes is provided with a gel cell carrier, the inner side surface of the support is fixedly installed with a second tooth plate corresponding to the position of the cutting table, the first gear matches the second tooth plate, a fixed seat that can move vertically up and down is provided above the cutting table, and a ring-shaped cutter is fixedly installed on the bottom surface of the fixed seat.

[0007] By adopting the above technical scheme, the movement of the slider drives the cutting knife and the scroll to move, and the cutting knife moves to cut the gel cell carrier inside the incubator. As the slider continues to move, the first gear rolls on the surface of the first tooth plate and drives the scroll to rotate. A layer of gel cell carrier cut by the cutting knife is rolled up on the surface of the film. Multiple sliders move in the opposite direction in the slide groove, and the gel cell carrier rolled up on the surface of the film follows the slider to move toward the cutting table. The first gear rolls on the surface of the second tooth plate and drives the scroll to rotate in the opposite direction, and the gel cell carrier rolled up on the surface of the film is spread out on the surface of the base film. The gel cell carriers rolled up on the surface of the film are neatly stacked up and down in sequence. Multiple scrolls correspond to the positions of multiple incubators, so that a layer of gel cell carrier is rolled up in the same position on the surface of the film, thereby preventing the gel cell carrier from being assembled misplaced. Compared with the push plate or tweezers, the use of the scroll to roll up ensures the stability of the shape and structure of the assembled cell carrier. The assembled gel cell carrier has a regular shape and structure, which ensures the effectiveness of subsequent human intrauterine transplantation operations and repair of endometrial damage.

[0008] Preferably, a support frame is fixedly mounted on the inner side surface of the bracket, an electric telescopic rod is fixedly mounted on the bottom surface of the support frame, and a telescopic end of the electric telescopic rod is fixedly connected to the surface of the fixing seat.

[0009] Preferably, a transmission device for conveying the base film is disposed inside the cutting table, a servo motor for driving the transmission device is fixedly mounted on the surface of the cutting table, and multiple layers of assembled cell carriers are stacked and placed on the surface of the base film.

[0010] Preferably, the internal rotation of the slide groove is connected with a screw rod, the slider is slidably connected to the slide groove through the screw rod, a first motor is fixedly mounted on the surface of one end of the bracket, the output end of the first motor is fixedly connected to the screw rod, a connecting frame is fixedly mounted on the inner side surface of one end of the bracket, a controller is fixedly mounted on the surface of the connecting frame, and the first motor is electrically connected to the controller through a wire.

[0011] Preferably, the electric telescopic rod is electrically connected to the controller via a wire, and the servo motor is electrically connected to the controller via a wire.

[0012] Preferably, the annular cutter includes two corresponding fixed knife plates, a first movable ring knife and a second movable ring knife, the two fixed knife plates are provided with movable grooves inside, the first movable ring knife and the second movable ring knife are both slidably connected to the fixed knife plates through the movable grooves, a partition is fixedly installed on the inner wall of the movable groove, a first spring is provided on both sides of the partition, the first movable ring knife and the second movable ring knife are elastically connected to the partition through the first spring, a fixed plate is fixedly installed between the two fixed knife plates, the corresponding end surfaces of the fixed plate are fixedly connected with threaded rods, one end of the two threaded rods respectively penetrates the first movable ring knife and the second movable ring knife, and the surfaces of the two threaded rods are provided with adjusting screws.

[0013] By adopting the above technical solution, the first movable ring knife and the second movable ring knife are moved toward the inside of the fixed knife plate to squeeze the first spring by turning the adjusting screw. During the process of adjusting the size of the ring cutter, the ruler is observed in real time, and the ring cutter is adjusted to a cutting specification suitable for the size of the endometrial damage, thereby increasing the function of the auxiliary device body and making the auxiliary device body multifunctional.

[0014] Preferably, a scale for observing the positions of the first movable ring knife and the second movable ring knife is provided on the surface of one of the fixed knife plates, and the scale is fixedly connected to the surface of the fixed knife plate.

[0015] By adopting the above technical solution and setting the scale, the movement positions of the first movable ring knife and the second movable ring knife can be observed in real time.

[0016] Preferably, a vertical plate is fixedly connected to the interior of the auxiliary equipment body, a movable groove is provided on the surface of the vertical plate, a movable frame matching the vertical plate is slidably connected to the interior of the movable groove, a movable plate is fixedly connected to one end of the movable frame, and the top surface of the movable plate is fixedly mounted with ramp blocks the same number as the incubator, a guide rod is slidably connected to the bottom surface of the incubator, one end of the guide rod is fixedly connected to the bottom surface of the culture dish, and the other end of the guide rod is fixedly connected to a ball head in contact with the ramp block, and a second spring is elastically connected between the culture dish and the incubator.

[0017] By adopting the above technical solution, the reciprocating motion of the moving plate causes the multiple ramp blocks to move, so that the ramp blocks squeeze the ball head to different degrees, and the guide rod follows the movement of the ball head to move the culture dish to stretch the second spring. The movement of the culture dish pushes the gel cell carrier inside the incubator out, and the ramp blocks squeeze the ball head to different degrees, so that the height of the gel cell carrier leaking out of the incubator can be adjusted, thereby achieving the cutting knife being able to cut gel cell carriers of different thicknesses.

[0018] Preferably, the bottom surface of the movable plate is fixedly connected to a third tooth plate, the bottom surface of the third tooth plate is rotatably connected to a second gear meshing therewith, a second motor is fixedly mounted on the surface of the vertical plate, and the output end of the second motor is fixedly connected to the second gear.

[0019] Preferably, one end of the second spring is fixedly connected to the bottom surface of the culture dish, and the other end of the second spring is fixedly connected to the inner bottom surface of the incubator.

[0020] Compared with the prior art, the present invention has the following beneficial effects:

[0021] 1) When the multi-cellular assembly installation auxiliary device for repairing endometrial damage is in operation, the movement of the slider drives the cutting knife and the reel to move, and the cutting knife moves to cut the gel cell carrier inside the incubator. As the slider continues to move, the first gear rolls on the surface of the first tooth plate and drives the reel to rotate. A layer of gel cell carrier cut by the cutting knife is rolled up on the surface of the film. Multiple sliders move in the opposite direction in the slide groove, and the gel cell carrier rolled up on the surface of the film moves toward the cutting table following the slider. The first gear rolls on the surface of the second tooth plate and drives the reel to rotate in the opposite direction, and the gel cell carrier rolled up on the surface of the film is spread out on the surface of the base film. The gel cell carriers rolled up on the surface of the film are neatly stacked up and down in sequence. Multiple reels correspond to the positions of multiple incubators, so that a layer of gel cell carrier is rolled up in the same position on the surface of the film, thereby preventing the gel cell carrier from being assembled misplaced. Compared with the push plate or tweezers, the use of the reel to roll up ensures the stability of the shape and structure of the assembled cell carrier. The assembled gel cell carrier has a regular shape and structure, which ensures the effectiveness of subsequent human intrauterine transplantation operations and repairing endometrial damage.

[0022] 2) When the multicellular assembly installation auxiliary device for repairing endometrial damage is in operation, the first movable ring knife and the second movable ring knife are moved toward the inside of the fixed knife plate to squeeze the first spring by turning the adjusting screw. During the process of adjusting the size of the annular cutter, the ruler is observed in real time, and the annular cutter is adjusted to a cutting specification suitable for the size of the endometrial damage, thereby increasing the function of the auxiliary device body and making the auxiliary device body multifunctional.

[0023] 3) When the multi-cellular assembly installation auxiliary device for repairing endometrial damage is in operation, the moving plate moves back and forth with the multiple ramp blocks, so that the ramp blocks squeeze the ball head to different degrees, and the guide rod follows the movement of the ball head to move the culture dish to stretch the second spring. The movement of the culture dish pushes the gel cell carrier inside the incubator out, and the ramp blocks squeeze the ball head to different degrees, so that the height of the gel cell carrier leaking out of the incubator is adjustable, so that the cutting knife can cut gel cell carriers of different thicknesses. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] Figure 1 It is a schematic diagram of the overall structure of the present invention;

[0025] Figure 2 It is a schematic diagram of the surface structure of the workbench of the present invention;

[0026] Figure 3 It is a schematic diagram of the position structure of the slide groove and the slider of the present invention;

[0027] Figure 4 It is a schematic diagram of the position structure of the movable plate and the ramp block of the present invention;

[0028] Figure 5 It is a schematic diagram of the position structure of the incubator and the first tooth plate of the present invention;

[0029] Figure 6 It is a schematic diagram of the cutting table structure of the present invention;

[0030] Figure 7 It is a schematic diagram of the structure of the annular cutter of the present invention;

[0031] Figure 8 It is a schematic diagram of the installation position structure of the fixing plate and the threaded rod of the present invention;

[0032] Fig. 9 It is a schematic diagram of the position structure of the movable frame and the movable plate of the present invention;

[0033] Fig.10 It is a schematic diagram of the internal structure of the incubator of the present invention.

[0034] Explanation of the numbers in the figure: 1. Auxiliary equipment body; 2. Workbench; 3. Bracket; 4. Slide; 5. Slider; 6. Cutter; 7. Scroll; 8. Film; 9. First gear; 10. Incubator; 11. First tooth plate; 12. Cutting table; 13. Transmission equipment; 14. Bottom film; 15. Gel cell carrier; 16. Support frame; 17. Electric telescopic rod; 18. Fixed seat; 19. Annular cutter; 20. Second tooth plate; 21. Screw; 22. First motor; 23. Connecting frame; 24. Controller; 25. Assemble the cell carrier; 26, servo motor; 27, first movable ring knife; 28, second movable ring knife; 29, movable groove; 30, partition; 31, first spring; 32, ruler; 33, fixed plate; 34, threaded rod; 35, adjustment screw; 36, vertical plate; 37, movable frame; 38, movable plate; 39, second motor; 40, movable groove; 41, third gear plate; 42, ramp block; 43, second gear; 44, culture dish; 45, guide rod; 46, ball head; 47, second spring; 48, fixed knife plate. DETAILED DESCRIPTION

[0035] Example 1

[0036] See also Figures 1 to 10, a multi-cell assembly installation auxiliary device for repairing endometrial damage, comprising an auxiliary device body 1, the auxiliary device body 1 can automatically produce multi-cell assemblies, a workbench 2 is fixedly installed on the top surface of the auxiliary device body 1, a bracket 3 is fixedly installed on one end surface of the workbench 2, a slide groove 4 is provided on the inner side of the bracket 3, a plurality of sliders 5 matching therewith are slidably connected inside the slide groove 4, a cutting knife 6 is fixedly installed on the surface of any slider 5, a reel 7 is rotatably connected to the surface of any slider 5, the reel 7 is located on one side of the cutting knife 6, a film 8 is fixedly coated on the surface of the reel 7, and a multilayer film 8 can be wound on the surface of the reel 7 according to the height of the gel cell carrier 15, so that the film 8 and the gel cell carrier 15 are located at the same The surface of the reel 7 is coaxially fixed with a first gear 9, which is meshed with a first tooth plate 11, and the first gear 9 rotates on the surface of the first tooth plate 11 in units of circles. The surface of the workbench 2 is fixedly connected with a culture box 10 of the same number as the slider 5, and the interior of the culture box 10 is slidably connected with a culture dish 44 matched thereto, and the culture dish 44 and the inner wall of the culture box 10 form a culture space. The culture box 10 is a conventional small temperature-controlled culture box 10 in the prior art. Cells are added to a culture space formed by the culture dish 44 and the inner wall of the culture box 10. The culture box 10 works to culture the cells for 30 to 60 minutes. After the cell culture is completed, gel is added (the viscosity of the gel is adjustable). After the cell block is stabilized, the culture dish 44 rises to The formed gel cells are pushed out, and then the next step of cutting, stacking and assembling is carried out. A first tooth plate 11 meshing with the first gear 9 is fixedly installed on the inner side of the bracket 3. The number of the first tooth plates 11 and the incubator 10 is the same, and the first tooth plates 11 correspond to the positions of the incubator 10. A cutting table 12 is fixedly installed on the surface of the workbench 2. The cutting table 12 is located on one side of the incubator 10. A paved bottom film 14 is provided on the surface of the cutting table 12. A gel cell carrier 15 is provided inside any incubator 10. The gel cell carrier 15 is a gel cell carrier 15 solidified by adding gel in the prior art. A second tooth plate 20 corresponding to the position of the cutting table 12 is fixedly installed on the inner side of the bracket 3. The first gear 9 matches the second tooth plate 20. The wheel 9 rotates in circles on the surface of the second tooth plate 20. A fixed seat 18 that can move vertically up and down is provided above the cutting table 12. A circular cutter 19 is fixedly installed on the bottom surface of the fixed seat 18. The movement of the slider 5 drives the cutting knife 6 and the reel 7 to move. The cutting knife 6 moves to cut the gel cell carrier 15 inside the incubator 10. As the slider 5 continues to move, the first gear 9 rolls on the surface of the first tooth plate 11 and drives the reel 7 to rotate. A layer of gel cell carrier 15 cut by the cutting knife 6 is rolled up on the surface of the film 8. Multiple sliders 5 move in the opposite direction in the slide groove 4. The gel cell carrier 15 rolled up on the surface of the film 8 follows the slider 5 to move toward the cutting table 12. The first gear 9 rolls on the surface of the second tooth plate 20 and drives the reel 7 to rotate in the opposite direction.The gel cell carrier 15 rolled up on the surface of the film 8 is spread flat on the surface of the base film 14, and the gel cell carriers 15 rolled up on the surface of the film 8 are stacked neatly up and down in sequence. The positions of multiple reels 7 correspond to the positions of multiple incubators 10, so that the positions of a layer of gel cell carrier 15 rolled up on the surface of the film 8 are consistent, thereby preventing the assembly of the gel cell carrier 15 from being misplaced. Compared with the push plate or tweezers, the shape and structure stability of the assembled cell carrier 25 are ensured by using the reel 7 for rolling up. The assembled gel cell carrier 15 has a regular shape and structure, which ensures the effectiveness of subsequent human intrauterine transplantation operations and repair of endometrial damage.

[0037] A support frame 16 is fixedly installed on the inner side surface of the bracket 3, and an electric telescopic rod 17 is fixedly installed on the bottom surface of the support frame 16. The electric telescopic rod 17 is a conventional electric control push rod in the prior art. The telescopic end of the electric telescopic rod 17 is fixedly connected to the surface of the fixed seat 18. The electric telescopic rod 17 provides power for the movement of the annular cutter 19.

[0038] A conveying device 13 for conveying a base film 14 is provided inside the cutting table 12. The conveying device 13 is a conventional device for conveying a base film 14 in the prior art. A servo motor 26 for driving the conveying device 13 is fixedly mounted on the surface of the cutting table 12. Multiple layers of assembled cell carriers 25 are stacked on the surface of the base film 14. The servo motor 26 is a conventional servo rotation device in the prior art.

[0039] The internal rotation of the slide groove 4 is connected with a screw rod 21, and the slider 5 is slidably connected to the slide groove 4 through the screw rod 21. A first motor 22 is fixedly installed on the surface of one end of the bracket 3. The first motor 22 is a conventional forward and reverse motor in the prior art. The output end of the first motor 22 is fixedly connected to the screw rod 21. A connecting frame 23 is fixedly installed on the inner side surface of one end of the bracket 3. A controller 24 is fixedly installed on the surface of the connecting frame 23. The first motor 22 is electrically connected to the controller 24 through a wire. The controller 24 is a conventional programmable controller 24 in the prior art.

[0040] The electric telescopic rod 17 is electrically connected to the controller 24 via a wire, and the servo motor 26 is electrically connected to the controller 24 via a wire.

[0041] The use steps of the present invention are as follows: when the multi-cell assembly installation auxiliary device for repairing endometrial damage is in use, in the initial position, multiple culture boxes 10 and multiple sliders 5 are arranged at staggered intervals. When multiple layers of cell carriers are superimposed, by operating the controller 24, the first motor 22 rotates forward and drives the lead screw 21 to rotate, and multiple equidistant sliders 5 move simultaneously in the slide groove 4. The movement of the slider 5 drives the cutting knife 6 and the reel 7 to move. The cutting knife 6 moves to cut the gel cell carrier 15 in the culture box 10. The surface of the reel 7 is at the same height as the gel cell carrier 15. When the first gear 9 moves to engage with the first tooth plate 11, as the slider 5 continues to move, the first gear 9 rolls on the surface of the first tooth plate 11 and drives the reel 7 to rotate. The surface of 7 is fixedly coated with a film 8, and a layer of gel cell carrier 15 cut by the cutting knife 6 is rolled up on the surface of the film 8. When the reel 7 completes the rolling of a layer of gel cell carrier 15, the first gear 9 is separated from the first tooth plate 11, and the multiple reels 7 complete the rolling of multiple layers of gel cell carriers 15. The first motor 22 reverses and drives the multiple sliders 5 to move in the opposite direction in the slide slot 4. At this time, the gel cell carrier 15 rolled up on the surface of the film 8 follows the slider 5 to move toward the cutting table 12. During the movement of the gel cell carrier 15 rolled up on the surface of the film 8, it will not contact the uncut surface of the gel cell carrier 15 inside the incubator 10. When the first gear 9 moves to contact with the second tooth plate 20, as the first The gear 9 rolls on the surface of the second tooth plate 20 and drives the reel 7 to rotate in the opposite direction. The servo motor 26 is started in advance, so that the transmission device 13 works to lay the base film 14 on the surface of the cutting table 12. The reel 7 rotates in the opposite direction to spread the gel cell carrier 15 rolled up on the surface of the film 8 on the surface of the base film 14. The gel cell carriers 15 rolled up on the surface of the film 8 are stacked neatly up and down in sequence. After the stacking is completed, the electric telescopic rod 17 extends and moves downward with the annular cutter 19 to cut the neatly stacked multi-layer assembled cell carriers 25. After the cutting is completed, the electric telescopic rod 17 retracts and resets the annular cutter 19. At this time, the assembled cell carrier 25 after cutting is removed from the surface of the cutting table 12. By operating the controller 24 again, multiple sliders are 5 moves to reset to the initial position, adjusts the height of the gel cell carrier 15, and repeats the above steps again. In this scheme, the slider 5 moves with the cutting knife 6 and the reel 7, and the cutting knife 6 moves to cut the gel cell carrier 15 inside the incubator 10. As the slider 5 continues to move, the first gear 9 rolls on the surface of the first tooth plate 11 and rotates with the reel 7. A layer of gel cell carrier 15 cut by the cutting knife 6 is rolled up on the surface of the film 8. Multiple sliders 5 move in the opposite direction in the slide 4. The gel cell carrier 15 rolled up on the surface of the film 8 follows the slider 5 to move toward the cutting table 12. The first gear 9 rolls on the surface of the second tooth plate 20 and rotates with the reel 7 in the opposite direction, and the gel cell carrier 15 rolled up on the surface of the film 8 is spread out on the surface of the base film 14.The gel cell carriers 15 rolled up on the surface of the film 8 are neatly stacked up and down in sequence. The positions of multiple reels 7 and multiple incubators 10 correspond to each other, so that the positions of a layer of gel cell carriers 15 rolled up on the surface of the film 8 are consistent, thereby preventing the gel cell carriers 15 from being assembled misplaced. Compared with the push plate or tweezers, the shape and structure stability of the assembled cell carriers 25 are ensured by rolling up with the reel 7. The assembled gel cell carriers 15 have regular shapes and structures, which ensures the effectiveness of subsequent human intrauterine transplantation operations and repair of endometrial damage.

[0042] Example 2

[0043] When repairing endometrial damage, it is necessary to select a multilayer assembled cell carrier 25 of appropriate size according to the size of the damage. The assembled cell carrier 25 needs to be cut into assembled cell carriers 25 of different sizes in advance. The problem is solved by the following solution.

[0044] See also Figures 1 to 10 , combined with the basis of Example 1, the difference is that the annular cutter 19 includes two corresponding fixed blade plates 48, a first movable ring knife 27 and a second movable ring knife 28, the two fixed blade plates 48 are provided with movable grooves 29 inside, the first movable ring knife 27 and the second movable ring knife 28 are both slidably connected to the fixed blade plates 48 through the movable grooves 29, a partition 30 is fixedly installed on the inner wall of the movable groove 29, and first springs 31 are provided on both sides of the partition 30, the first movable ring knife 27 and the second movable ring knife 28 are elastically connected to the partition 30 through the first spring 31, and a fixed plate 33 is fixedly installed between the two fixed blade plates 48, The corresponding end surfaces of the fixed plate 33 are fixedly connected with threaded rods 34, and one end of the two threaded rods 34 passes through the first movable ring knife 27 and the second movable ring knife 28 respectively. The surfaces of the two threaded rods 34 are provided with adjusting screws 35. By rotating the adjusting screws 35, the first movable ring knife 27 and the second movable ring knife 28 move toward the inside of the fixed knife plate 48 to squeeze the first spring 31. During the process of adjusting the size of the annular cutter 19, the scale 32 is observed in real time, and the annular cutter 19 is adjusted to a cutting specification suitable for the size of the endometrial damage, thereby increasing the function of the auxiliary device body 1 and making the auxiliary device body 1 multifunctional.

[0045] The surface of one of the fixed knife plates 48 is provided with a scale 32 for observing the positions of the first movable ring knife 27 and the second movable ring knife 28. The scale 32 is fixedly connected to the surface of the fixed knife plate 48. The setting of the scale 32 can observe the movement positions of the first movable ring knife 27 and the second movable ring knife 28 in real time.

[0046] The use steps of the present invention are as follows: when the multi-cellular assembly installation auxiliary device for repairing endometrial damage is in use, before the annular cutter 19 cuts the neatly stacked assembled cell carriers 25, the overall size of the annular cutter 19 is adjusted according to the size of the endometrial damage. During the adjustment, the first movable annular cutter 27 and the second movable annular cutter 28 are moved toward the inside of the fixed knife plate 48 to squeeze the first spring 31 by rotating the adjusting screw 35. During the process of adjusting the size of the annular cutter 19, the ruler 32 is observed in real time, so that the annular cutter 19 is adjusted to a cutting specification that is suitable for the size of the endometrial damage. This scheme increases the function of the auxiliary device body 1 and makes the auxiliary device body 1 multifunctional.

[0047] Example 3

[0048] The thickness of the assembled cell carrier 25 is different, so the gel cell carriers 15 of different thicknesses inside the incubator 10 need to be cut. The problem can be solved by the following solution.

[0049] See also Figures 1 to 10 , the difference from the embodiment 1 is that a vertical plate 36 is fixedly connected inside the auxiliary device body 1, a movable groove 40 is opened on the surface of the vertical plate 36, a movable frame 37 matching with it is slidably connected inside the movable groove 40, a movable plate 38 is fixedly connected to one end of the movable frame 37, and the top surface of the movable plate 38 is fixedly installed with the same number of slope blocks 42 as the incubator 10, and a guide rod 45 is slidably connected to the bottom surface of the incubator 10, one end of the guide rod 45 is fixedly connected to the bottom surface of the culture dish 44, and the other end of the guide rod 45 is fixedly connected to a ball head 46 in contact with the slope block 42 A second spring 47 is elastically connected between the culture dish 44 and the incubator 10. The movable plate 38 reciprocates to move the multiple ramp blocks 42, so that the ramp blocks 42 squeeze the ball heads 46 to different degrees. The guide rod 45 follows the movement of the ball heads 46 to move the culture dish 44 to stretch the second spring 47. The movement of the culture dish 44 pushes the gel cell carrier 15 inside the incubator 10 out. The ramp blocks 42 squeeze the ball heads 46 to different degrees, so that the height of the gel cell carrier 15 leaking out of the incubator 10 is adjustable, so that the cutting knife 6 can cut gel cell carriers 15 of different thicknesses.

[0050] The bottom surface of the movable plate 38 is fixedly connected to a third tooth plate 41, and the bottom surface of the third tooth plate 41 is rotatably connected to a second gear 43 meshing therewith. A second motor 39 is fixedly installed on the surface of the vertical plate 36, and the output end of the second motor 39 is fixedly connected to the second gear 43. The second motor 39 is a conventional forward and reverse motor in the prior art.

[0051] One end of the second spring 47 is fixedly connected to the bottom surface of the culture dish 44 , and the other end of the second spring 47 is fixedly connected to the inner bottom surface of the incubator 10 . The second spring 47 is used to reset the culture dish 44 .

[0052] The use steps of the present invention are as follows: when the multi-cellular assembly installation auxiliary device for repairing endometrial damage is used, the controller 24 is operated, and the second motor 39 rotates forward and reversely with the second gear 43, so that the movable plate 38 reciprocates and moves with the multiple ramp blocks 42, so that the ramp blocks 42 squeeze the ball head 46 to different degrees, and the guide rod 45 follows the movement of the ball head 46 to move the culture dish 44 to stretch the second spring 47, and the culture dish 44 moves to push out the gel cell carrier 15 inside the incubator 10. This scheme uses the movable plate 38 to reciprocate and move with the multiple ramp blocks 42, so that the ramp blocks 42 squeeze the ball head 46 to different degrees, and the guide rod 45 follows the movement of the ball head 46 to move the culture dish 44 to stretch the second spring 47, and the culture dish 44 moves to push out the gel cell carrier 15 inside the incubator 10. The ramp block 42 squeezes the ball head 46 to different degrees, so that the height of the gel cell carrier 15 leaking out of the incubator 10 is adjustable, so that the cutting knife 6 can cut gel cell carriers 15 of different thicknesses.

[0053] The above shows and describes the basic principles, main features and advantages of the present invention. Those skilled in the art should understand that the present invention is not limited by the above embodiments. The above embodiments and descriptions are only preferred examples of the present invention and are not intended to limit the present invention. Without departing from the spirit and scope of the present invention, the present invention may have various changes and improvements, which fall within the scope of the present invention. The scope of protection of the present invention is defined by the attached claims and their equivalents.

Claims

1. A multi-cell assembly installation auxiliary device for repairing endometrial damage, comprising an auxiliary device body (1), characterized in that: A workbench (2) is fixedly mounted on the top surface of the auxiliary equipment body (1), a bracket (3) is fixedly mounted on one end surface of the workbench (2), a slide groove (4) is provided on the inner side surface of the bracket (3), a plurality of sliders (5) matching therewith are slidably connected inside the slide groove (4), a cutting knife (6) is fixedly mounted on the surface of any one of the sliders (5), a reel (7) is rotatably connected to the surface of any one of the sliders (5), the reel (7) is located on one side of the cutting knife (6), a film (8) is fixedly coated on the surface of the reel (7), a first gear (9) is coaxially fixedly mounted on the surface of the reel (7), the surface of the workbench (2) is fixedly connected with the same number of incubators (10) as the sliders (5), the interior of the incubators (10) is slidably connected with culture dishes (44) matching therewith, the inner side of the bracket (3) A first tooth plate (11) meshing with a first gear (9) is fixedly installed on the surface of the workbench (2), the number of the first tooth plates (11) is the same as that of the incubator (10), and the positions of the first tooth plates (11) and the incubator (10) correspond. A cutting table (12) is fixedly installed on the surface of the workbench (2), the cutting table (12) is located on one side of the incubator (10), the surface of the cutting table (12) is provided with a paved bottom film (14), and a gel cell carrier (15) is provided inside any of the incubators (10). A second tooth plate (20) corresponding to the position of the cutting table (12) is fixedly installed on the inner side surface of the bracket (3), the first gear (9) matches the second tooth plate (20), a fixed seat (18) capable of vertical up and down movement is provided above the cutting table (12), and a ring-shaped cutter (19) is fixedly installed on the bottom surface of the fixed seat (18).

2. The multi-cell assembly installation auxiliary device for repairing endometrial damage according to claim 1, characterized in that: A support frame (16) is fixedly mounted on the inner side surface of the bracket (3), an electric telescopic rod (17) is fixedly mounted on the bottom surface of the support frame (16), and the telescopic end of the electric telescopic rod (17) is fixedly connected to the surface of the fixing seat (18).

3. The multi-cell assembly installation auxiliary device for repairing endometrial damage according to claim 1, characterized in that: A transmission device (13) for transmitting a base film (14) is arranged inside the cutting table (12), a servo motor (26) for driving the transmission device (13) is fixedly mounted on the surface of the cutting table (12), and multiple layers of assembled cell carriers (25) are stacked and placed on the surface of the base film (14).

4. The multi-cell assembly installation auxiliary device for repairing endometrial damage according to claim 1, characterized in that: The slide groove (4) is internally rotatably connected with a screw rod (21), the slider (5) is slidably connected to the slide groove (4) through the screw rod (21), a first motor (22) is fixedly mounted on the surface of one end of the bracket (3), the output end of the first motor (22) is fixedly connected to the screw rod (21), a connecting frame (23) is fixedly mounted on the inner side surface of one end of the bracket (3), a controller (24) is fixedly mounted on the surface of the connecting frame (23), and the first motor (22) is electrically connected to the controller (24) through a wire.

5. The multi-cell assembly installation auxiliary device for repairing endometrial damage according to claim 3, characterized in that: The electric telescopic rod (17) is electrically connected to the controller (24) via a wire, and the servo motor (26) is electrically connected to the controller (24) via a wire.

6. The multi-cell assembly installation auxiliary device for repairing endometrial damage according to claim 1, characterized in that: The annular cutter (19) comprises two corresponding fixed blade plates (48), a first movable ring blade (27) and a second movable ring blade (28). The two fixed blade plates (48) are provided with movable grooves (29) inside. The first movable ring blade (27) and the second movable ring blade (28) are both slidably connected to the fixed blade plate (48) through the movable grooves (29). A partition plate (30) is fixedly installed on the inner wall of the movable groove (29). Both sides of the partition plate (30) are provided with first springs (31). The first movable ring knife (27) and the second movable ring knife (28) are elastically connected to the partition (30) via a first spring (31); a fixed plate (33) is fixedly installed between the two fixed knife plates (48); the corresponding end surfaces of the fixed plate (33) are fixedly connected with threaded rods (34); one end of the two threaded rods (34) respectively penetrates the first movable ring knife (27) and the second movable ring knife (28); and the surfaces of the two threaded rods (34) are provided with adjusting screws (35).

7. The multi-cell assembly installation auxiliary device for repairing endometrial damage according to claim 6, characterized in that: A scale (32) for observing the positions of the first movable ring knife (27) and the second movable ring knife (28) is provided on the surface of one of the fixed knife plates (48), and the scale (32) is fixedly connected to the surface of the fixed knife plate (48).

8. The multi-cell assembly installation auxiliary device for repairing endometrial damage according to claim 1, characterized in that: The auxiliary equipment body (1) is fixedly connected with a vertical plate (36) inside, a movable groove (40) is provided on the surface of the vertical plate (36), a movable frame (37) matching with the vertical plate (36) is slidably connected inside the movable groove (40), a movable plate (38) is fixedly connected to one end of the movable frame (37), a slope block (42) the same number as the incubator (10) is fixedly mounted on the top surface of the movable plate (38), a guide rod (45) is slidably connected to the bottom surface of the incubator (10), one end of the guide rod (45) is fixedly connected to the bottom surface of the incubator (44), the other end of the guide rod (45) is fixedly connected to a ball head (46) in contact with the slope block (42), and a second spring (47) is elastically connected between the incubator (44) and the incubator (10).

9. The multi-cell assembly installation auxiliary device for repairing endometrial damage according to claim 8, characterized in that: The bottom surface of the movable plate (38) is fixedly connected to a third tooth plate (41), and the bottom surface of the third tooth plate (41) is rotatably connected to a second gear (43) meshing therewith. A second motor (39) is fixedly mounted on the surface of the vertical plate (36), and an output end of the second motor (39) is fixedly connected to the second gear (43).

10. The multi-cell assembly installation auxiliary device for repairing endometrial damage according to claim 8, characterized in that: One end of the second spring (47) is fixedly connected to the bottom surface of the culture dish (44), and the other end of the second spring (47) is fixedly connected to the inner bottom surface of the culture box (10).

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