Traditional Chinese medicine for treating hyperthyroidism
By using formulas composed of Chinese medicinal materials such as yellow medicine, capsule dosage forms are made, which solves the problem of iodine agents in treating acute reactions and chronic iodine poisoning in hyperthyroidism, effectively alleviating the symptoms of hyperthyroidism and improving immunity, and ensuring the safety of the drug Sex and efficacy.
Patent Information
- Application Number
- CN202411730741.5
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2024-11-28
- Publication Date
- 2025-01-14
- Estimated Expiration
- Not applicable · inactive patent
AI Technical Summary
Existing iodine agents for treating hyperthyroidism may cause acute reactions and chronic iodine poisoning after taking the medication, and long-term use increases the risk of hyperthyroidism, making it difficult to effectively alleviate the symptoms of hyperthyroidism, enlargement and decreased immunity caused by hyperthyroidism.
Using the traditional Chinese medicine formula consisting of yellow yam, raw yam, oyster, sauerkum, sea pumice, raw astragalus, fritillaria, seaweed and Codonopsis, the uniformity and stability of the drug are ensured through granulation and capsule dosage forms, and targeting hyperthyroidism. The pathological characteristics of the disease regulate endocrine and relieve symptoms.
This Chinese medicine formula can effectively inhibit thyroid hormone synthesis, improve metabolic status, relieve swelling and indigestion caused by hyperthyroidism, enhance immunity, and reduce thyroid function. It has clear efficacy and low side effects, ensuring the safety and effectiveness of the drug .
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Figure CN119303034A_ABST
Abstract
Description
Technical Field
[0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine for treating hyperthyroidism. Background Art
[0002] Chinese medicine refers to medicines that are collected, processed, and prepared under the guidance of traditional Chinese medical theories, explain their mechanisms of action, and guide their clinical applications. Chinese medicine refers to substances that are used to prevent, treat, and diagnose diseases and have rehabilitation and health-care effects under the guidance of TCM theories. Chinese medicines are mainly derived from natural medicines and their processed products, including herbal medicines, animal medicines, mineral medicines, and some chemical and biological medicines. The harvesting season and method of Chinese medicines are closely related to ensuring the quality of the medicines, because the effective and harmful components contained in the medicinal parts of plants and animals at different stages of their growth and development are different, so the efficacy and toxic side effects of the medicines are often quite different, so the harvesting of medicinal materials must be timely. It must be collected at the appropriate time. Hyperthyroidism, abbreviated as hyperthyroidism, is a disease caused by excessive production and secretion of thyroid hormone due to overactive thyroid gland. There are multiple factors causing hyperthyroidism, including genetic factors and immune system dysfunction, which produces antibodies against the thyroid gland, leading to excessive secretion of thyroid hormone, and long-term excessive iodine intake. Some infections or thyroid inflammation may destroy thyroid cells and release too much thyroid hormone. Long-term mental stress, anxiety, depression and other emotional states may affect the neuroendocrine system. Diseases such as pituitary adenoma and thyroid follicular cancer may also lead to excessive secretion of thyroid hormone.
[0003] Currently, some treatments for hyperthyroidism use iodine, but iodine may cause acute reactions immediately or a few hours after administration. At the same time, iodine may induce thyroid dysfunction, including hyperthyroidism and hypothyroidism. Long-term use or excessive use may increase the risk of hyperthyroidism, and long-term use of iodine may lead to chronic iodine poisoning, which may have a certain impact on the patient's daily life. Summary of the invention
[0004] The object of the present invention is to provide a traditional Chinese medicine for treating hyperthyroidism to solve the problems raised in the above background technology.
[0005] To achieve the above purpose, the present invention provides the following technical solution: a traditional Chinese medicine for treating hyperthyroidism, comprising the following weight grams: 30 grams of Dioscorea bulbifera, 30 grams of raw yam, 20 grams of oyster, 15 grams of Prunella vulgaris, 15 grams of pumice, 15 grams of raw Astragalus, 12 grams of Fritillaria thunbergii, 12 grams of Kelp, 12 grams of Sargassum and 12 grams of Codonopsis pilosula.
[0006] The present invention also provides a method for preparing a traditional Chinese medicine for treating hyperthyroidism, comprising the following steps:
[0007] S1. Preparation and pretreatment of medicinal materials: wash each medicinal material separately, and then dry, crush and screen the medicinal materials;
[0008] S2, mixing and blending: weighing the raw materials according to the formula and then mixing them;
[0009] S3, granulation and drying: adding the uniformly mixed powder into a granulator, granulating it, and then drying the prepared granules;
[0010] S4, capsule filling and packaging: filling the dried granules into capsules, and then packaging the capsules;
[0011] S5. Quality inspection and packaging: Carry out quality inspection on the manufactured capsules, and then package the qualified capsules.
[0012] Preferably, in said S1, when washing the medicinal materials, it is necessary to remove impurities such as dirt and dust on the surface of the medicinal materials, and the washed medicinal materials are dried in an oven.
[0013] Preferably, in said S1, after the medicinal materials are dried, the medicinal materials are put into a grinder for grinding, and after grinding, they are screened by a sifter to remove larger particles.
[0014] Preferably, in said S2, when weighing the medicinal material powder, it is necessary to use an electronic scale to accurately weigh it, and in said S2, when mixing the medicinal material powder, it is necessary to check the mixing uniformity.
[0015] Preferably, in S3, when the medicinal material powder is granulated, the granulation pressure is set at 10-50 MPa, the granulation temperature is room temperature-60°C, the particle size is 0.5-2 mm, and the particles are screened through a sieve after the granulation is completed.
[0016] Preferably, in S3, the screened particles need to be placed in an oven for drying to remove excess moisture.
[0017] Preferably, in S4, it is necessary to select a suitable capsule model according to the size and shape of the particles, control the filling amount during the filling process, and after the filling is completed, the capsule is packaged by a packaging machine.
[0018] Preferably, in S5, after the capsules are packaged, the capsules need to be inspected for appearance, weight and drug content.
[0019] Preferably, in S5, when packaging the drug, the drug name, specification, production date, expiration date, batch number and manufacturer need to be indicated.
[0020] Compared with the prior art, the present invention has the following beneficial effects:
[0021] The present invention provides Dioscorea bulbifera, which can inhibit the synthesis of thyroid hormones, and can help relieve the symptoms of hypermetabolism and increased excitability caused by hyperthyroidism by reducing the secretion of thyroid hormones. It also has the effect of resolving phlegm and dispersing nodules, and can improve the symptoms of goiter caused by hyperthyroidism. Raw yam, the nutrients contained in yam are helpful to improve the metabolic status of patients, and yam is rich in dietary fiber, which can promote gastrointestinal motility and help relieve the symptoms of indigestion in patients with hyperthyroidism. Oysters are provided, which have the effect of softening and dispersing nodules, and have a certain effect on the treatment of goiter. At the same time, Prunella vulgaris can clear the heat in the body, reduce thyroid function, and relieve the eye symptoms caused by hyperthyroidism, such as proptosis, red and swollen eyes, etc. The sea pumice is provided, which has a salty taste and cold nature, belongs to the lung meridian, and has the effects of clearing lung fire, The effect of relieving cough and relieving asthma, the thyroid hormone level of hyperthyroidism patients is high, and they may experience breathing difficulties. Drinking a moderate amount of pumice soaked in water can help alleviate the symptoms. Codonopsis pilosula and Astragalus membranaceus can enhance the patient's physique, improve the body's immunity, and help patients better cope with the problems of physical exhaustion and decreased immunity caused by hyperthyroidism. Seaweed, kelp and Fritillaria thunbergii help to reduce goiter and relieve the compression symptoms caused by hyperthyroidism. At the same time, the medicinal materials in the present invention are all traditional Chinese medicines commonly used in the treatment of hyperthyroidism. These Chinese medicines have been clinically verified for a long time, have clear therapeutic effects and low side effects, and ensure the safety and effectiveness of the drugs. The weight of various medicinal materials is reasonably designed. According to the pathological characteristics of hyperthyroidism, the therapeutic effect is achieved by regulating the endocrine system and balancing the thyroid function, thereby enhancing the pertinence and efficacy of the drugs. BRIEF DESCRIPTION OF THE DRAWINGS
[0022] Figure 1 The present invention is a schematic structural diagram of a preferred embodiment of a traditional Chinese medicine for treating hyperthyroidism provided by the present invention. DETAILED DESCRIPTION
[0023] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.
[0024] See also Figure 1As shown, a traditional Chinese medicine for treating hyperthyroidism includes the following weights: 30 grams of Dioscorea bulbifera, 30 grams of raw yam, 20 grams of oyster, 15 grams of Prunella vulgaris, 15 grams of pumice, 15 grams of raw Astragalus, 12 grams of Fritillaria thunbergii, 12 grams of Kelp, 12 grams of seaweed and 12 grams of Codonopsis pilosula.
[0025] refer to Figure 1 The present invention also provides a method for preparing a traditional Chinese medicine for treating hyperthyroidism, comprising the following steps:
[0026] S1. Preparation and pretreatment of medicinal materials: Each medicinal material is cleaned separately, and then dried, crushed and screened. Cleaning can remove dirt, impurities and microorganisms on the surface of the medicinal materials, improving the sanitary quality of the medicinal materials. The drying process can remove excess moisture in the medicinal materials to prevent mildew and bacterial growth. Crushing and screening make the medicinal materials easier for subsequent processing and the uniformity of the preparation. At the same time, particles of appropriate size are screened out to ensure the effective release of the drug and the comfort of the patient.
[0027] S2. Mixing and blending: Weigh the raw materials according to the formula and then mix them. Accurately weighing each raw material according to the formula can ensure the correct proportion of each ingredient to achieve the desired therapeutic effect. The mixing process makes the various ingredients evenly distributed, avoiding local concentrations that are too high or too low, and improving the stability and reliability of the drug.
[0028] S3, granulation and drying: Add the evenly mixed powder into the granulator, granulate it, and then dry the granules; through the precise control of the granulator, the size, shape and hardness of the granules can be adjusted to meet the needs of different drugs. The drying process removes excess moisture in the granules, improves the stability and shelf life of the drug, and also facilitates subsequent packaging and storage.
[0029] S4. Capsule filling and packaging: Fill the dried granules into capsules, and then package the capsules; filling the dried granules into capsules can protect the drugs from the external environment, and the packaging process ensures the integrity and sealing of the capsules, preventing the drugs from being contaminated or deteriorating during storage and transportation. The capsule dosage form is also convenient for patients to carry and take
[0030] S5. Quality inspection and packaging: Carry out quality inspection on the manufactured capsules, and then package the qualified capsules.
[0031] In S1, when washing the medicinal materials, it is necessary to remove impurities such as dirt and dust on the surface of the medicinal materials, and the washed medicinal materials are dried in an oven. Washing the medicinal materials can effectively remove the dirt, dust and impurities on the surface, ensure the purity of the medicinal materials, thereby improving the quality and safety of the medicines. Drying the medicinal materials can remove excess moisture and prevent the medicinal materials from mold and deterioration during storage, which is also beneficial to the subsequent crushing and granulation operations.
[0032] In S1, after the medicinal materials are dried, they are put into a grinder for crushing. After crushing, they are screened by a sifter to remove larger particles. Crushing the medicinal materials into powder can improve the solubility and bioavailability of the drug, and the screening operation can remove larger particles, ensuring the uniformity and fineness of the medicinal material powder, which is beneficial to subsequent mixing and granulation.
[0033] In S2, when weighing the medicinal powder, it is necessary to use an electronic scale to accurately weigh it. In S2, when mixing the medicinal powder, it is necessary to check its mixing uniformity. Using an electronic scale for accurate weighing can ensure that the amount of each medicinal material is accurate, thereby ensuring the accuracy of the drug formula and the stability of the efficacy. The mixing uniformity check can ensure that the medicinal powder is evenly distributed in the mixture to avoid the situation where the local concentration is too high or too low.
[0034] In S3, when granulating the medicinal powder, the granulation pressure is set at 10-50MPa, the granulation temperature is room temperature-60℃, the particle size is 0.5-2mm, and the particles are screened through a sieve after granulation. The granulation operation can make the medicinal powder into granules, which is convenient for patients to swallow and digest. At the same time, by adjusting the pressure and temperature of the granulator, the size and shape of the particles can be controlled to meet the needs of different patients. The screening operation can remove particles that do not meet the requirements to ensure the uniformity and consistency of the particles.
[0035] In S3, the screened particles need to be placed in an oven for drying to remove excess moisture. The drying operation can remove excess moisture from the particles and prevent the drug from becoming moldy and deteriorating due to excessive moisture during storage. At the same time, the dried particles are easier to package and store, which is also beneficial to improving the stability of the drug and extending its shelf life.
[0036] In S4, it is necessary to select the appropriate capsule model according to the size and shape of the particles, control the filling amount during the filling process, and after the filling is completed, the capsule is encapsulated by the encapsulation machine. Selecting the appropriate capsule model according to the size and shape of the particles can ensure the filling amount and uniformity of the drug in the capsule, and controlling the filling amount can ensure that the drug content in each capsule is consistent, thereby ensuring the stability of the therapeutic effect. The encapsulation operation can protect the drug from the influence of the external environment and improve the hygiene and safety of the drug.
[0037] In S5, after the capsules are packaged, they need to be inspected for appearance, weight, and drug content. Quality inspections such as appearance inspection, weight inspection, and drug content inspection can ensure that the quality of the capsules meets the standards, which can not only improve the safety of medication for patients, but also enhance patients' trust and satisfaction with the drugs.
[0038] In S5, when packaging, the drug name, specifications, production date, expiration date, batch number and manufacturer need to be indicated.
[0039] Embodiment 1
[0040] The formula is according to the following weights: 30 grams of Dioscorea bulbifera, 35 grams of raw yam, 20 grams of oyster, 15 grams of Prunella vulgaris, 15 grams of pumice, 10 grams of raw Astragalus, 12 grams of Fritillaria thunbergii, 12 grams of Laminaria japonica, 12 grams of seaweed and 12 grams of Codonopsis pilosula. First, the medicinal materials are washed, and after washing, the medicinal materials are dried in an oven. After drying, the medicinal materials are crushed by a grinder, and then the medicinal material powders are screened. After screening, various medicinal material powders are mixed to make the various medicinal material powders evenly mixed. After mixing, the powders are added into a granulator for granulation, and the granulation pressure is controlled to be set at 10-50MPa, the granulation temperature is room temperature-60°C, and the particle size is 0.5-2mm. Then, the granulated particles are dried, and then the particles are directly filled into capsules, and the capsules are sealed. At the same time, when the capsules are taken, the frequency of taking is two to three times a day, and the dosage is four capsules at a time.
[0041] Embodiment 2
[0042] The formula is according to the following weights: 35 grams of Dioscorea bulbifera, 28 grams of raw yam, 18 grams of oyster, 13 grams of Prunella vulgaris, 13 grams of pumice, 14 grams of raw Astragalus, 11 grams of Fritillaria thunbergii, 10 grams of kelp, 10 grams of seaweed and 10 grams of Codonopsis pilosula. First, the medicinal materials are washed, and after washing, the medicinal materials are dried in an oven. After drying, the medicinal materials are crushed by a grinder, and then the medicinal material powders are screened. After screening, various medicinal material powders are mixed to make the various medicinal material powders evenly mixed. After mixing, the powders are added into a granulator for granulation, and the granulation pressure is controlled to be set at 10-50MPa, the granulation temperature is room temperature-60°C, and the particle size is 0.5-2mm. Then, the granulated particles are dried, and then the particles are directly filled into capsules, and the capsules are sealed. At the same time, when the capsules are taken, the frequency of taking is two to three times a day, and the dosage is four capsules at a time.
[0043] Embodiment 3
[0044] The formula is in accordance with the following weights: 30 grams of Dioscorea bulbifera, 30 grams of raw yam, 20 grams of oyster, 15 grams of Prunella vulgaris, 15 grams of pumice, 15 grams of raw Astragalus, 12 grams of Fritillaria thunbergii, 12 grams of kelp, 12 grams of seaweed and 12 grams of Codonopsis pilosula. First, the medicinal materials are washed, and after washing, the medicinal materials are dried in an oven, and after drying, the medicinal materials are crushed by a grinder, and then the medicinal material powders are screened, and after screening, various medicinal material powders are mixed so that the various medicinal material powders are mixed evenly, and after mixing, the powders are added into a granulator for granulation, and the granulation pressure is controlled to be set at 10-50MPa, the granulation temperature is room temperature-60°C, and the particle size is 0.5-2mm, and then the granules after granulation are dried, and then the particles are directly filled into capsules, and the capsules are sealed, and when the capsules are taken, the frequency of taking is two to three times a day, and the dosage is four capsules at a time.
[0045] According to the above embodiments, the capsule prepared in Embodiment 3 has a better effect, and it treats the pathological characteristics of hyperthyroidism, relieves symptoms, and improves the health of patients.
[0046] Working principle: When the user uses traditional Chinese medicine to treat hyperthyroidism, first weigh 30 grams of Dioscorea bulbifera, 30 grams of raw yam, 20 grams of oyster, 15 grams of Prunella vulgaris, 15 grams of pumice, 15 grams of raw Astragalus, 12 grams of Fritillaria thunbergii, 12 grams of kelp, 12 grams of seaweed and 12 grams of Codonopsis pilosula. First, wash each medicinal material to remove impurities such as dirt and dust on the surface. After washing, dry it in an oven to ensure the dryness and hygiene of the medicinal materials. After drying, put the medicinal materials into a grinder for crushing, and screen them through a sifter to remove larger particles to ensure the uniformity and fineness of the medicinal powder. Then, accurately weigh the raw materials according to the formula, use an electronic scale to ensure that the amount of each medicinal material is accurate, and then mix the medicinal powder. During the mixing process, its uniformity needs to be checked to ensure that each medicinal material can be evenly distributed in the mixture. Add the evenly mixed powder to the granulator, and adjust the pressure and temperature of the granulator. The granulation pressure is set at 10-50MPa, and the granulation temperature is room temperature-60℃. The powder is made into granules, and the particle size is controlled between 0.5 and 2㎜ to ensure that it is easy to swallow and digest. After the granulation is completed, the particles are screened through a sieve to remove particles that do not meet the requirements. Then, the screened particles are placed in an oven for drying to remove excess moisture to ensure their stability and shelf life. Then, according to the size and shape of the particles, the appropriate capsule model is selected. During the filling process, the filling amount is controlled to ensure that the drug content in each capsule is consistent. After filling is completed, the capsules are packaged by a packaging machine to ensure their sealing and hygiene. The finished capsules are then subjected to quality inspection, including appearance inspection, weight inspection and drug content inspection, etc., to ensure that they meet quality standards. Then, qualified capsules are packaged, and the drug name, specifications, production date, expiration date, batch number and manufacturer and other information are marked on the packaging for easy use and management by patients.
[0047] It should be noted that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device. In the absence of further restrictions, the elements defined by the sentence "comprise a ..." do not exclude the existence of other identical elements in the process, method, article or device including the elements.
[0048] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.
Claims
1. A Chinese medicine for treating hyperthyroidism, characterized in that: It includes the following weights in grams: 30 grams of Dioscorea bulbifera, 30 grams of raw yam, 20 grams of oyster, 15 grams of Prunella vulgaris, 15 grams of pumice, 15 grams of raw Astragalus, 12 grams of Fritillaria thunbergii, 12 grams of kelp, 12 grams of seaweed and 12 grams of Codonopsis pilosula.
2. A method for preparing a traditional Chinese medicine for treating hyperthyroidism according to claim 1, characterized in that: The following steps are involved: S1. Preparation and pretreatment of medicinal materials: Each medicinal material is cleaned separately, and then dried, crushed and screened; S2, mixing and blending: weighing the raw materials according to the formula and then mixing them; S3, granulation and drying: adding the uniformly mixed powder into a granulator, granulating it, and then drying the prepared granules; S4, capsule filling and packaging: filling the dried granules into capsules, and then packaging the capsules; S5. Quality inspection and packaging: Carry out quality inspection on the manufactured capsules, and then package the qualified capsules.
3. A method for preparing a traditional Chinese medicine for treating hyperthyroidism according to claim 2, characterized in that: In S1, when washing the medicinal materials, it is necessary to remove impurities such as dirt and dust on the surface of the medicinal materials, and the washed medicinal materials are dried in an oven.
4. A method for preparing a traditional Chinese medicine for treating hyperthyroidism according to claim 2, characterized in that: In the step S1, after the medicinal materials are dried, the medicinal materials are put into a grinder for grinding. After grinding, the medicinal materials are screened by a sifter to remove larger particles.
5. A method for preparing a traditional Chinese medicine for treating hyperthyroidism according to claim 2, characterized in that: In the above S2, when the medicinal material powder is weighed, it is necessary to use an electronic scale to accurately weigh it. In the above S2, when the medicinal material powder is mixed, it is necessary to check the mixing uniformity.
6. A method for preparing a traditional Chinese medicine for treating hyperthyroidism according to claim 2, characterized in that: In S3, when the medicinal material powder is granulated, the granulation pressure is set at 10-50 MPa, the granulation temperature is room temperature-60°C, the particle size is 0.5-2 mm, and the particles are screened through a sieve after the granulation is completed.
7. A method for preparing a traditional Chinese medicine for treating hyperthyroidism according to claim 2, characterized in that: In S3, the screened particles need to be placed in an oven for drying to remove excess moisture.
8. A method for preparing a traditional Chinese medicine for treating hyperthyroidism according to claim 2, characterized in that: In S4, it is necessary to select a suitable capsule model according to the size and shape of the particles, control the filling amount during the filling process, and after the filling is completed, the capsule is packaged by a packaging machine.
9. A method for preparing a traditional Chinese medicine for treating hyperthyroidism according to claim 2, characterized in that: In S5, after the capsules are packaged, the capsules need to be inspected for appearance, weight and drug content.
10. The method for preparing a traditional Chinese medicine for treating hyperthyroidism according to claim 2, characterized in that: In S5, when packaging the drug, the drug name, specification, production date, expiration date, batch number and manufacturer need to be indicated.