Extraction process of folium artemisiae argyi volatile oil

Abstract

The invention discloses a folium artemisiae argyi volatile oil extraction process, which comprises: a material preparation step: taking a predetermined amount of folium artemisiae argyi, washing with low-temperature pure water, centrifuging to remove water through a hydro-extracting machine, and carrying out freeze-drying treatment on the folium artemisiae argyi through a freeze-drying machine; and a crushing step: crushing the freeze-dried folium artemisiae argyi by using a crusher, and then screening to obtain folium artemisiae argyi powder. The folium artemisiae argyi is cleaned by low-temperature pure water, and the cleaning time and temperature are strictly controlled, so that impurities on the surface of the folium artemisiae argyi can be effectively removed, the folium artemisiae argyi volatile oil is purer during extraction, and the folium artemisiae argyi volatile oil cannot be lost during cleaning; meanwhile, the folium artemisiae argyi volatile oil can be effectively permeated into water better through crushing and gas boiling, so that the effects of high purity and high extraction rate during extraction of the folium artemisiae argyi volatile oil are achieved.

Description

Technical Field

[0001] The invention relates to the technical field of extraction of wormwood volatile oil, and in particular to an extraction process of wormwood volatile oil. Background Art

[0002] Mugwort essential oil is a volatile aromatic substance extracted from the leaves and stems of mugwort. It is a multi-component mixture, the main components of which include terpinenol-4, β-caryophyllene, artemisinin, linalool, camphor, borneol, eucalyptol, phellandrene, etc., and has high medicinal value.

[0003] Chinese patent application number CN201610015691.1 discloses a process for extracting volatile oil from mugwort leaves, comprising the following steps: (1) washing and removing impurities from mugwort leaves, drying at low temperature, and crushing to obtain mugwort leaf powder; (2) adding warm water to the mugwort leaf powder to soak it until it expands, and freezing it at -6-0°C for 2-3 hours; thawing the frozen mugwort leaf powder by microwave; (3) adding 10-15 times the weight of water to the thawed mugwort leaf powder, soaking it for 5-10 hours, and then steam distilling the mugwort leaf powder and the soaking liquid for 5-8 hours, and collecting the distillate; after the distillate is allowed to stand and cool to separate into layers, taking the upper oil layer to obtain volatile oil from mugwort leaves.

[0004] The volatile oil of Artemisia argyi is usually extracted by steam distillation. If the volatile oil of Artemisia argyi is washed by water in a conventional way before extraction, the volatile oil will be lost during the washing process; if it is not washed, the pollutants and impurities on the surface of Artemisia argyi will affect the purity after purification, and the current extraction rate of volatile oil of Artemisia argyi is low. Therefore, it is urgent to design an extraction process of volatile oil of Artemisia argyi to solve the above problems. Summary of the invention

[0005] The object of the present invention is to provide a process for extracting volatile oil from Artemisia argyi to solve the above-mentioned deficiencies in the prior art.

[0006] In order to achieve the above object, the present invention provides the following technical solutions:

[0007] A process for extracting wormwood volatile oil comprises the following steps:

[0008] Preparation steps: taking a predetermined amount of mugwort leaves and washing them with low-temperature pure water, then centrifuging them to remove water through a water spinner, and freeze-drying the mugwort leaves using a freeze dryer;

[0009] Crushing step: crushing the freeze-dried mugwort leaves with a crusher, and then passing through a sieve to obtain mugwort leaf powder;

[0010] Soaking step: putting the wormwood leaf powder into a container with a stirring function, then adding a certain amount of distilled water for soaking, and stirring the water in the container during the soaking process;

[0011] Gas boiling treatment steps: connect a conduit to the gas outlet of the air pump, connect the other end of the conduit to the spinneret, put the spinneret into the bottom of the container and fix it, and continuously introduce air into the spinneret through the air pump;

[0012] Extraction step: adding the solution in the container and the precipitated wormwood powder into a volatile oil extractor, and heating the volatile oil extractor, so that when the solution is heated to boiling, cold water is passed into the condenser of the volatile oil extractor, and the volatile oil is collected;

[0013] Purification step: The collected volatile oil is subjected to anhydrous sodium sulfate to absorb excess water, then weighed, and the extraction rate of the volatile oil is calculated.

[0014] Furthermore, in the material preparation step, the time for cleaning the mugwort leaves is 10-30 seconds, and the water temperature is 4-8°C.

[0015] Furthermore, in the pulverizing step, the rotation speed of the pulverizer during pulverizing is 1000-3000 rpm, and the mesh size of the sieve is 50-80 meshes.

[0016] Furthermore, in the soaking step, the amount of distilled water added is 6-14 times the volume of the mugwort leaves, and the soaking time is 10-40 minutes.

[0017] Furthermore, in the gas-boiling treatment step, the gas outlet surface of the spinneret faces upward, and the air pump ventilates the interior of the container for 10-40 minutes.

[0018] Furthermore, in the extraction step, the temperature of the steam when the solution boils is 105° C., and the extraction time is 3-7 hours.

[0019] Furthermore, in the material preparation step, the water spinner works for 3-5 minutes and has a rotation speed of 1000-1500 rpm.

[0020] In the above technical scheme, the present invention provides an extraction process of wormwood volatile oil, which has the following beneficial effects: the present invention washes wormwood with low-temperature pure water and strictly controls the washing time and temperature, which can effectively remove impurities in the wormwood, making the wormwood volatile oil purer during extraction, and the wormwood volatile oil will not be lost during washing. At the same time, the wormwood volatile oil can be effectively and better penetrated into the water through crushing and gas boiling, thereby achieving the effects of high purity and high extraction rate during the extraction of wormwood volatile oil. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the drawings required for use in the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments recorded in the present invention. For ordinary technicians in this field, other drawings can also be obtained based on these drawings.

[0022] Figure 1 The present invention is a process flow chart of extracting wormwood volatile oil. DETAILED DESCRIPTION

[0023] In order to enable those skilled in the art to better understand the technical solution of the present invention, the present invention will be further described in detail below with reference to the accompanying drawings.

[0024] Example 1

[0025] The present invention provides a method for extracting volatile oil from Artemisia argyi, comprising the following steps:

[0026] Preparation steps: taking a predetermined amount of mugwort leaves and washing them with low-temperature pure water, the mass of the mugwort leaves is 100g, the volume of 100g mugwort leaves is about 1L, the volatile oil in the mugwort leaves is prevented from diffusing into the washed pure water by low temperature, and then the water is centrifuged out by a water spinner, the water spinner can quickly remove a large amount of water, and the mugwort leaves are freeze-dried by a freeze dryer, the freeze-drying of the mugwort leaves can effectively increase the drying speed and prevent the volatile oil from volatilizing, the washing time of the mugwort leaves is 20S, the water temperature is 4°C, the working time of the water spinner is 5min, and the speed of the water spinner is 1000 rpm;

[0027] Crushing step: crushing the freeze-dried wormwood leaf with a crusher, crushing the wormwood leaf so that the extraction rate of the volatile oil of the wormwood leaf is higher, and then passing through a sieve to obtain wormwood leaf powder, after which the stalks containing less volatile oil in the wormwood leaf can be removed, and during the crushing, the speed of the crusher is 2000 rpm, and the mesh number of the sieve is 60 meshes;

[0028] Soaking step: put the wormwood leaf powder into a container with a stirring function, then add a certain amount of distilled water for soaking, and stir the water in the container during the soaking process. The stirring effect allows the volatile oil to diffuse better into the water. The amount of distilled water added is 10 times the volume of the wormwood leaf, that is, 10L of distilled water, and the soaking time is 20 minutes;

[0029] Gas-boiling treatment step: connect a catheter at the air outlet of the air pump, connect the other end of the catheter to a spinneret, and place the spinneret at the bottom of the container for fixing, continuously introduce air into the spinneret through the air pump, the air outlet surface of the spinneret faces upward, and air can flow out from a number of small holes on the surface of the spinneret to form a number of bubbles, so that the bubbles float to the liquid surface and explode, and the exploded bubbles will generate energy, so that the wormwood leaf volatile oil can be more thoroughly diffused into the water, and the continuously floating bubbles will cause the solution to continuously roll, which is more conducive to the diffusion of the wormwood leaf volatile oil into the water, and the air pump ventilates the inside of the container for 20 minutes, and the gas-boiling treatment step is carried out simultaneously with the soaking step;

[0030] Extraction step: adding the solution in the container and the precipitated wormwood powder into a volatile oil extractor, and heating the volatile oil extractor, so that when the solution is heated to boiling, cold water is passed into the condenser of the volatile oil extractor, and the volatile oil is collected, the temperature of the steam when the solution boils is 105° C., and the extraction time is 3 hours;

[0031] Purification step: The collected volatile oil is subjected to anhydrous sodium sulfate to absorb excess water, and then weighed to obtain a total of 0.566g of wormwood volatile oil, and the extraction rate of the volatile oil is calculated.

[0032] Example 2

[0033] The present invention provides a method for extracting volatile oil from Artemisia argyi, comprising the following steps:

[0034] Preparation steps: taking a predetermined amount of mugwort leaves and washing them with low-temperature pure water, the mass of the mugwort leaves is 100g, the volume of 100g mugwort leaves is about 1L, the volatile oil in the mugwort leaves is prevented from diffusing into the washed pure water by low temperature, and then the water is centrifuged out by a water spinner, the water spinner can quickly remove a large amount of water, and the mugwort leaves are freeze-dried by a freeze dryer, the freeze-drying of the mugwort leaves can effectively increase the drying speed and prevent the volatile oil from volatilizing, the washing time of the mugwort leaves is 20S, the water temperature is 4°C, the working time of the water spinner is 5min, and the speed of the water spinner is 1000 rpm;

[0035] Crushing step: crushing the freeze-dried wormwood leaf with a crusher, crushing the wormwood leaf so that the extraction rate of the volatile oil of the wormwood leaf is higher, and then passing through a sieve to obtain wormwood leaf powder, after which the stalks containing less volatile oil in the wormwood leaf can be removed, and during the crushing, the speed of the crusher is 2000 rpm, and the mesh number of the sieve is 60 meshes;

[0036] Soaking step: put the wormwood leaf powder into a container with a stirring function, then add a certain amount of distilled water for soaking, and stir the water in the container during the soaking process. The stirring effect allows the volatile oil to diffuse better into the water. The amount of distilled water added is 10 times the volume of the wormwood leaf, that is, 10L of distilled water, and the soaking time is 30 minutes;

[0037] Gas-boiling treatment step: connect a catheter at the air outlet of the air pump, connect the other end of the catheter to a spinneret, and place the spinneret at the bottom of the container for fixing, continuously introduce air into the spinneret through the air pump, the air outlet surface of the spinneret faces upward, and air can flow out from a number of small holes on the surface of the spinneret to form a number of bubbles, so that the bubbles float to the liquid surface and explode, and the exploded bubbles will generate energy, so that the wormwood leaf volatile oil can be more thoroughly diffused into the water, and the continuously floating bubbles will cause the solution to continuously roll, which is more conducive to the diffusion of the wormwood leaf volatile oil into the water, and the air pump ventilates the inside of the container for 30 minutes, and the gas-boiling treatment step is carried out simultaneously with the soaking step;

[0038] Extraction step: adding the solution in the container and the precipitated wormwood powder into a volatile oil extractor, and heating the volatile oil extractor, so that when the solution is heated to boiling, cold water is passed into the condenser of the volatile oil extractor, and the volatile oil is collected, the temperature of the steam when the solution boils is 105° C., and the extraction time is 4.5 hours;

[0039] Purification step: The collected volatile oil is subjected to anhydrous sodium sulfate to absorb excess water, and then weighed to obtain a total of 0.642 g of wormwood volatile oil, and the extraction rate of the volatile oil is calculated.

[0040] Example 3

[0041] The present invention provides a method for extracting volatile oil from Artemisia argyi, comprising the following steps:

[0042] Preparation steps: taking a predetermined amount of mugwort leaves and washing them with low-temperature pure water, the mass of the mugwort leaves is 100g, the volume of 100g mugwort leaves is about 1L, the volatile oil in the mugwort leaves is prevented from diffusing into the washed pure water by low temperature, and then the water is centrifuged out by a water spinner, the water spinner can quickly remove a large amount of water, and the mugwort leaves are freeze-dried by a freeze dryer, the freeze-drying of the mugwort leaves can effectively increase the drying speed and prevent the volatile oil from volatilizing, the washing time of the mugwort leaves is 20S, the water temperature is 4°C, the working time of the water spinner is 5min, and the speed of the water spinner is 1000 rpm;

[0043] Crushing step: crushing the freeze-dried wormwood leaf with a crusher, crushing the wormwood leaf so that the extraction rate of the volatile oil of the wormwood leaf is higher, and then passing through a sieve to obtain wormwood leaf powder, after which the stalks containing less volatile oil in the wormwood leaf can be removed, and during the crushing, the speed of the crusher is 2000 rpm, and the mesh number of the sieve is 60 meshes;

[0044] Soaking step: put the wormwood leaf powder into a container with a stirring function, then add a certain amount of distilled water for soaking, and stir the water in the container during the soaking process. The stirring effect allows the volatile oil to diffuse better into the water. The amount of distilled water added is 10 times the volume of the wormwood leaf, that is, 10L of distilled water, and the soaking time is 40 minutes;

[0045] Gas-boiling treatment step: connect a catheter at the air outlet of the air pump, connect the other end of the catheter to a spinneret, and place the spinneret at the bottom of the container for fixing, continuously introduce air into the spinneret through the air pump, the air outlet surface of the spinneret faces upward, and air can flow out from a number of small holes on the surface of the spinneret to form a number of bubbles, so that the bubbles float to the liquid surface and explode, and the exploded bubbles will generate energy, so that the wormwood leaf volatile oil can be more thoroughly diffused into the water, and the continuously floating bubbles will cause the solution to continuously roll, which is more conducive to the diffusion of the wormwood leaf volatile oil into the water, and the air pump ventilates the inside of the container for 40 minutes, and the gas-boiling treatment step is carried out simultaneously with the soaking step;

[0046] Extraction step: adding the solution in the container and the precipitated wormwood powder into a volatile oil extractor, and heating the volatile oil extractor, so that when the solution is heated to boiling, cold water is passed into the condenser of the volatile oil extractor, and the volatile oil is collected, the temperature of the steam when the solution boils is 105° C., and the extraction time is 6 hours;

[0047] Purification step: The collected volatile oil is subjected to anhydrous sodium sulfate to absorb excess water, and then weighed to obtain a total of 0.679 g of wormwood volatile oil, and the extraction rate of the volatile oil is calculated.

[0048] Example 4

[0049] The present invention provides a method for extracting volatile oil from Artemisia argyi, comprising the following steps:

[0050] Preparation steps: taking a predetermined amount of mugwort leaves and washing them with low-temperature pure water, the mass of the mugwort leaves is 100g, the volume of 100g mugwort leaves is about 1L, the volatile oil in the mugwort leaves is prevented from diffusing into the washed pure water by low temperature, and then the water is centrifuged out by a water spinner, the water spinner can quickly remove a large amount of water, and the mugwort leaves are freeze-dried by a freeze dryer, the freeze-drying of the mugwort leaves can effectively increase the drying speed and prevent the volatile oil from volatilizing, the washing time of the mugwort leaves is 20S, the water temperature is 4°C, the working time of the water spinner is 5min, and the speed of the water spinner is 1000 rpm;

[0051] Crushing step: crushing the freeze-dried wormwood leaf with a crusher, crushing the wormwood leaf so that the extraction rate of the volatile oil of the wormwood leaf is higher, and then passing through a sieve to obtain wormwood leaf powder, after which the stalks containing less volatile oil in the wormwood leaf can be removed, and during the crushing, the speed of the crusher is 2000 rpm, and the mesh number of the sieve is 60 meshes;

[0052] Soaking step: put the wormwood leaf powder into a container with a stirring function, then add a certain amount of distilled water for soaking, and stir the water in the container during the soaking process. The stirring effect allows the volatile oil to diffuse better into the water. The amount of distilled water added is 12 times the volume of the wormwood leaf, that is, 12L of distilled water, and the soaking time is 20 minutes;

[0053] Gas-boiling treatment step: connect a catheter at the air outlet of the air pump, connect the other end of the catheter to a spinneret, and place the spinneret at the bottom of the container for fixing, continuously introduce air into the spinneret through the air pump, the air outlet surface of the spinneret faces upward, and air can flow out from a number of small holes on the surface of the spinneret to form a number of bubbles, so that the bubbles float to the liquid surface and explode, and the exploded bubbles will generate energy, so that the wormwood leaf volatile oil can be more thoroughly diffused into the water, and the continuously floating bubbles will cause the solution to continuously roll, which is more conducive to the diffusion of the wormwood leaf volatile oil into the water, and the air pump ventilates the inside of the container for 20 minutes, and the gas-boiling treatment step is carried out simultaneously with the soaking step;

[0054] Extraction step: adding the solution in the container and the precipitated wormwood powder into a volatile oil extractor, and heating the volatile oil extractor, so that when the solution is heated to boiling, cold water is passed into the condenser of the volatile oil extractor, and the volatile oil is collected, the temperature of the steam when the solution boils is 105° C., and the extraction time is 4.5 hours;

[0055] Purification step: The collected volatile oil is subjected to anhydrous sodium sulfate to absorb excess water, and then weighed to obtain a total of 0.543 g of wormwood volatile oil, and the extraction rate of the volatile oil is calculated.

[0056] Example 5

[0057] The present invention provides a method for extracting volatile oil from Artemisia argyi, comprising the following steps:

[0058] Preparation steps: taking a predetermined amount of mugwort leaves and washing them with low-temperature pure water, the mass of the mugwort leaves is 100g, the volume of 100g mugwort leaves is about 1L, the volatile oil in the mugwort leaves is prevented from diffusing into the washed pure water by low temperature, and then the water is centrifuged out by a water spinner, the water spinner can quickly remove a large amount of water, and the mugwort leaves are freeze-dried by a freeze dryer, the freeze-drying of the mugwort leaves can effectively increase the drying speed and prevent the volatile oil from volatilizing, the washing time of the mugwort leaves is 20S, the water temperature is 4°C, the working time of the water spinner is 5min, and the speed of the water spinner is 1000 rpm;

[0059] Crushing step: crushing the freeze-dried wormwood leaf with a crusher, crushing the wormwood leaf so that the extraction rate of the volatile oil of the wormwood leaf is higher, and then passing through a sieve to obtain wormwood leaf powder, after which the stalks containing less volatile oil in the wormwood leaf can be removed, and during the crushing, the speed of the crusher is 2000 rpm, and the mesh number of the sieve is 60 meshes;

[0060] Soaking step: put the wormwood leaf powder into a container with a stirring function, then add a certain amount of distilled water for soaking, and stir the water in the container during the soaking process. The stirring effect allows the volatile oil to diffuse better into the water. The amount of distilled water added is 12 times the volume of the wormwood leaf, that is, 12L of distilled water, and the soaking time is 30 minutes;

[0061] Gas-boiling treatment step: connect a catheter at the air outlet of the air pump, connect the other end of the catheter to a spinneret, and place the spinneret at the bottom of the container for fixing, continuously introduce air into the spinneret through the air pump, the air outlet surface of the spinneret faces upward, and air can flow out from a number of small holes on the surface of the spinneret to form a number of bubbles, so that the bubbles float to the liquid surface and explode, and the exploded bubbles will generate energy, so that the wormwood leaf volatile oil can be more thoroughly diffused into the water, and the continuously floating bubbles will cause the solution to continuously roll, which is more conducive to the diffusion of the wormwood leaf volatile oil into the water, and the air pump ventilates the inside of the container for 30 minutes, and the gas-boiling treatment step is carried out simultaneously with the soaking step;

[0062] Extraction step: adding the solution in the container and the precipitated wormwood powder into a volatile oil extractor, and heating the volatile oil extractor, so that when the solution is heated to boiling, cold water is passed into the condenser of the volatile oil extractor, and the volatile oil is collected, the temperature of the steam when the solution boils is 105° C., and the extraction time is 6 hours;

[0063] Purification step: The collected volatile oil is subjected to anhydrous sodium sulfate to absorb excess water, and then weighed to obtain a total of 0.657 g of wormwood volatile oil, and the extraction rate of the volatile oil is calculated.

[0064] Example 6

[0065] The present invention provides a method for extracting volatile oil from Artemisia argyi, comprising the following steps:

[0066] Preparation steps: taking a predetermined amount of mugwort leaves and washing them with low-temperature pure water, the mass of the mugwort leaves is 100g, the volume of 100g mugwort leaves is about 1L, the volatile oil in the mugwort leaves is prevented from diffusing into the washed pure water by low temperature, and then the water is centrifuged out by a water spinner, the water spinner can quickly remove a large amount of water, and the mugwort leaves are freeze-dried by a freeze dryer, the freeze-drying of the mugwort leaves can effectively increase the drying speed and prevent the volatile oil from volatilizing, the washing time of the mugwort leaves is 20S, the water temperature is 4°C, the working time of the water spinner is 5min, and the speed of the water spinner is 1000 rpm;

[0067] Crushing step: crushing the freeze-dried wormwood leaf with a crusher, crushing the wormwood leaf so that the extraction rate of the volatile oil of the wormwood leaf is higher, and then passing through a sieve to obtain wormwood leaf powder, after which the stalks containing less volatile oil in the wormwood leaf can be removed, and during the crushing, the speed of the crusher is 2000 rpm, and the mesh number of the sieve is 60 meshes;

[0068] Soaking step: put the wormwood leaf powder into a container with a stirring function, then add a certain amount of distilled water for soaking, and stir the water in the container during the soaking process. The stirring effect allows the volatile oil to diffuse better into the water. The amount of distilled water added is 12 times the volume of the wormwood leaf, that is, 12L of distilled water, and the soaking time is 40 minutes;

[0069] Gas-boiling treatment step: connect a catheter at the air outlet of the air pump, connect the other end of the catheter to a spinneret, and place the spinneret at the bottom of the container for fixing, continuously introduce air into the spinneret through the air pump, the air outlet surface of the spinneret faces upward, and air can flow out from a number of small holes on the surface of the spinneret to form a number of bubbles, so that the bubbles float to the liquid surface and explode, and the exploded bubbles will generate energy, so that the wormwood leaf volatile oil can be more thoroughly diffused into the water, and the continuously floating bubbles will cause the solution to continuously roll, which is more conducive to the diffusion of the wormwood leaf volatile oil into the water, and the air pump ventilates the inside of the container for 40 minutes, and the gas-boiling treatment step is carried out simultaneously with the soaking step;

[0070] Extraction step: adding the solution in the container and the precipitated wormwood powder into a volatile oil extractor, and heating the volatile oil extractor, so that when the solution is heated to boiling, cold water is passed into the condenser of the volatile oil extractor, and the volatile oil is collected, the temperature of the steam when the solution boils is 105° C., and the extraction time is 3 hours;

[0071] Purification step: The collected volatile oil is subjected to anhydrous sodium sulfate to absorb excess water, and then weighed to obtain a total of 0.506 g of wormwood volatile oil, and the extraction rate of the volatile oil is calculated.

[0072] Example 7

[0073] The present invention provides a method for extracting volatile oil from Artemisia argyi, comprising the following steps:

[0074] Preparation steps: taking a predetermined amount of mugwort leaves and washing them with low-temperature pure water, the mass of the mugwort leaves is 100g, the volume of 100g mugwort leaves is about 1L, the volatile oil in the mugwort leaves is prevented from diffusing into the washed pure water by low temperature, and then the water is centrifuged out by a water spinner, the water spinner can quickly remove a large amount of water, and the mugwort leaves are freeze-dried by a freeze dryer, the freeze-drying of the mugwort leaves can effectively increase the drying speed and prevent the volatile oil from volatilizing, the washing time of the mugwort leaves is 20S, the water temperature is 4°C, the working time of the water spinner is 5min, and the speed of the water spinner is 1000 rpm;

[0075] Crushing step: crushing the freeze-dried wormwood leaf with a crusher, crushing the wormwood leaf so that the extraction rate of the volatile oil of the wormwood leaf is higher, and then passing through a sieve to obtain wormwood leaf powder, after which the stalks containing less volatile oil in the wormwood leaf can be removed, and during the crushing, the speed of the crusher is 2000 rpm, and the mesh number of the sieve is 60 meshes;

[0076] Soaking step: put the wormwood leaf powder into a container with a stirring function, then add a certain amount of distilled water for soaking, and stir the water in the container during the soaking process. The stirring effect allows the volatile oil to be better diffused into the water. The amount of distilled water added is 14 times the volume of the wormwood leaf, that is, 14L of distilled water, and the soaking time is 20 minutes;

[0077] Gas-boiling treatment step: connect a catheter at the air outlet of the air pump, connect the other end of the catheter to a spinneret, and place the spinneret at the bottom of the container for fixing, continuously introduce air into the spinneret through the air pump, the air outlet surface of the spinneret faces upward, and air can flow out from a number of small holes on the surface of the spinneret to form a number of bubbles, so that the bubbles float to the liquid surface and explode, and the exploded bubbles will generate energy, so that the wormwood leaf volatile oil can be more thoroughly diffused into the water, and the continuously floating bubbles will cause the solution to continuously roll, which is more conducive to the diffusion of the wormwood leaf volatile oil into the water, and the air pump ventilates the inside of the container for 20 minutes, and the gas-boiling treatment step is carried out simultaneously with the soaking step;

[0078] Extraction step: adding the solution in the container and the precipitated wormwood powder into a volatile oil extractor, and heating the volatile oil extractor, so that when the solution is heated to boiling, cold water is passed into the condenser of the volatile oil extractor, and the volatile oil is collected, the temperature of the steam when the solution boils is 105° C., and the extraction time is 6 hours;

[0079] Purification step: The collected volatile oil is subjected to anhydrous sodium sulfate to absorb excess water, and then weighed to obtain a total of 0.604 g of wormwood volatile oil, and the extraction rate of the volatile oil is calculated.

[0080] Example 8

[0081] The present invention provides a method for extracting volatile oil from Artemisia argyi, comprising the following steps:

[0082] Preparation steps: taking a predetermined amount of mugwort leaves and washing them with low-temperature pure water, the mass of the mugwort leaves is 100g, the volume of 100g mugwort leaves is about 1L, the volatile oil in the mugwort leaves is prevented from diffusing into the washed pure water by low temperature, and then the water is centrifuged out by a water spinner, the water spinner can quickly remove a large amount of water, and the mugwort leaves are freeze-dried by a freeze dryer, the freeze-drying of the mugwort leaves can effectively increase the drying speed and prevent the volatile oil from volatilizing, the washing time of the mugwort leaves is 20S, the water temperature is 4°C, the working time of the water spinner is 5min, and the speed of the water spinner is 1000 rpm;

[0083] Crushing step: crushing the freeze-dried wormwood leaf with a crusher, crushing the wormwood leaf so that the extraction rate of the volatile oil of the wormwood leaf is higher, and then passing through a sieve to obtain wormwood leaf powder, after which the stalks containing less volatile oil in the wormwood leaf can be removed, and during the crushing, the speed of the crusher is 2000 rpm, and the mesh number of the sieve is 60 meshes;

[0084] Soaking step: put the wormwood leaf powder into a container with a stirring function, then add a certain amount of distilled water for soaking, and stir the water in the container during the soaking process. The stirring effect allows the volatile oil to diffuse better into the water. The amount of distilled water added is 14 times the volume of the wormwood leaf, that is, 14L of distilled water, and the soaking time is 30 minutes;

[0085] Gas-boiling treatment step: connect a catheter at the air outlet of the air pump, connect the other end of the catheter to a spinneret, and place the spinneret at the bottom of the container for fixing, continuously introduce air into the spinneret through the air pump, the air outlet surface of the spinneret faces upward, and air can flow out from a number of small holes on the surface of the spinneret to form a number of bubbles, so that the bubbles float to the liquid surface and explode, and the exploded bubbles will generate energy, so that the wormwood leaf volatile oil can be more thoroughly diffused into the water, and the continuously floating bubbles will cause the solution to continuously roll, which is more conducive to the diffusion of the wormwood leaf volatile oil into the water, and the air pump ventilates the inside of the container for 30 minutes, and the gas-boiling treatment step is carried out simultaneously with the soaking step;

[0086] Extraction step: adding the solution in the container and the precipitated wormwood powder into a volatile oil extractor, and heating the volatile oil extractor, so that when the solution is heated to boiling, cold water is passed into the condenser of the volatile oil extractor, and the volatile oil is collected, the temperature of the steam when the solution boils is 105° C., and the extraction time is 3 hours;

[0087] Purification step: The collected volatile oil is subjected to anhydrous sodium sulfate to absorb excess water, and then weighed to obtain a total of 0.506 g of wormwood volatile oil, and the extraction rate of the volatile oil is calculated.

[0088] Example 9

[0089] The present invention provides a method for extracting volatile oil from Artemisia argyi, comprising the following steps:

[0090] Preparation steps: taking a predetermined amount of mugwort leaves and washing them with low-temperature pure water, the mass of the mugwort leaves is 100g, the volume of 100g mugwort leaves is about 1L, the volatile oil in the mugwort leaves is prevented from diffusing into the washed pure water by low temperature, and then the water is centrifuged out by a water spinner, the water spinner can quickly remove a large amount of water, and the mugwort leaves are freeze-dried by a freeze dryer, the freeze-drying of the mugwort leaves can effectively increase the drying speed and prevent the volatile oil from volatilizing, the washing time of the mugwort leaves is 20S, the water temperature is 4°C, the working time of the water spinner is 5min, and the speed of the water spinner is 1000 rpm;

[0091] Crushing step: crushing the freeze-dried wormwood leaf with a crusher, crushing the wormwood leaf so that the extraction rate of the volatile oil of the wormwood leaf is higher, and then passing through a sieve to obtain wormwood leaf powder, after which the stalks containing less volatile oil in the wormwood leaf can be removed, and during the crushing, the speed of the crusher is 2000 rpm, and the mesh number of the sieve is 60 meshes;

[0092] Soaking step: put the wormwood leaf powder into a container with a stirring function, then add a certain amount of distilled water for soaking, and stir the water in the container during the soaking process. The stirring effect allows the volatile oil to diffuse better into the water. The amount of distilled water added is 14 times the volume of the wormwood leaf, that is, 14L of distilled water, and the soaking time is 40 minutes;

[0093] Gas-boiling treatment step: connect a catheter at the air outlet of the air pump, connect the other end of the catheter to a spinneret, and place the spinneret at the bottom of the container for fixing, continuously introduce air into the spinneret through the air pump, the air outlet surface of the spinneret faces upward, and air can flow out from a number of small holes on the surface of the spinneret to form a number of bubbles, so that the bubbles float to the liquid surface and explode, and the exploded bubbles will generate energy, so that the wormwood leaf volatile oil can be more thoroughly diffused into the water, and the continuously floating bubbles will cause the solution to continuously roll, which is more conducive to the diffusion of the wormwood leaf volatile oil into the water, and the air pump ventilates the inside of the container for 40 minutes, and the gas-boiling treatment step is carried out simultaneously with the soaking step;

[0094] Extraction step: adding the solution in the container and the precipitated wormwood powder into a volatile oil extractor, and heating the volatile oil extractor, so that when the solution is heated to boiling, cold water is passed into the condenser of the volatile oil extractor, and the volatile oil is collected, the temperature of the steam when the solution boils is 105° C., and the extraction time is 4.5 hours;

[0095] Purification step: The collected volatile oil is subjected to anhydrous sodium sulfate to absorb excess water, and then weighed to obtain a total of 0.528 g of wormwood volatile oil, and the extraction rate of the volatile oil is calculated.

[0096] In the above examples 1-9, the extraction rate of the volatile oil was calculated according to the weight of the wormwood volatile oil obtained in each example. The specific extraction rate formula of the volatile oil is:

[0097]

[0098] According to the above formula, the volatile oil extraction rate (%) of each of Examples 1-9 was calculated, and then an orthogonal test design was performed. Combined with the single factor test results, the volatile oil extraction rate was used as the investigation index, and the water addition amount (A), soaking time (B) and extraction time (C) were selected as the investigation factors in the orthogonal test. Each single factor was designed with three levels. According to L9(3 4) Orthogonal test table, the results are shown in Table 1 and Table 2.

[0099]

[0100]

[0101] Table 1 Analysis of orthogonal test results of volatile oil extraction from Artemisia argyi

[0102]

[0103] Table 2 Analysis of variance for orthogonal test of volatile oil extraction from Artemisia argyi

[0104] In Table 1 and Table 2, the K1, K2, and K3 values ​​in each column are the sum of the rates of the corresponding factors at the first, second, and third levels, respectively. For example, K1 of factor A with water added = 0.566 + 0.642 + 0.679 = 1.887, which is the sum of the rates of all A at the first level (10 times the water added) in nine tests. Similarly, K2 of factor A with water added = 0.543 + 0.657 + 0.506 = 1.706 and

[0105] K3 = 0.604 + 0.506 + 0.528 = 1.638 is the sum of the volatile oil extraction rates of all A at the second level (12 times the amount of water added) and the third level (14 times the amount of water added). The k1, k2, and k3 of each column are the average conversion rates obtained by dividing the K1, K2, and K3 of this column by 3; R represents the range; the p value is used to evaluate whether the influence of each factor on the experimental results is significant. In this experiment, according to statistical common sense, the standard significance level of 0.05 is used as the significance level value of this experiment. If the p value is less than 0.05, the influence of the factor is considered to be significant.

[0106] As shown in Table 1, the influence of each factor on the extraction rate of wormwood volatile oil is: extraction time> water addition> soaking time. According to the variance analysis, the difference between factor A and factor C is statistically significant (P<0.05), that is, the amount of water added and the extraction time have a significant effect on the extraction rate of wormwood volatile oil, and the soaking time B has a small effect on the extraction rate of wormwood volatile oil, with no significant difference (P>0.05). Based on the above analysis results, the best process combination is A1B2C3, that is, the best conditions for the extraction process are: adding 10 times of water; soaking time 30min; extraction time 6h, and the yield of wormwood volatile oil under this combination condition is the highest.

[0107] The above description is only by way of illustration of certain exemplary embodiments of the present invention. It is undoubted that those skilled in the art can modify the described embodiments in various ways without departing from the spirit and scope of the present invention. Therefore, the above drawings and descriptions are illustrative in nature and should not be construed as limiting the scope of protection of the claims of the present invention.

Claims

1. A process for extracting volatile oil from Artemisia argyi, characterized in that: The following steps are involved: Preparation steps: taking a predetermined amount of mugwort leaves and washing them with low-temperature pure water, then centrifuging them to remove water through a water spinner, and freeze-drying the mugwort leaves using a freeze dryer; Crushing step: crushing the freeze-dried mugwort leaves with a crusher, and then passing through a sieve to obtain mugwort leaf powder; Soaking step: putting the wormwood leaf powder into a container with a stirring function, then adding a certain amount of distilled water for soaking, and stirring the water in the container during the soaking process; Gas boiling treatment steps: connect a conduit to the gas outlet of the air pump, connect the other end of the conduit to the spinneret, put the spinneret into the bottom of the container and fix it, and continuously introduce air into the spinneret through the air pump; Extraction step: adding the solution in the container and the precipitated wormwood powder into a volatile oil extractor, and heating the volatile oil extractor, so that when the solution is heated to boiling, cold water is passed into the condenser of the volatile oil extractor, and the volatile oil is collected; Purification step: The collected volatile oil is subjected to anhydrous sodium sulfate to absorb excess water, then weighed, and the extraction rate of the volatile oil is calculated.

2. The extraction process of wormwood volatile oil according to claim 1, characterized in that: In the material preparation step, the time for cleaning the mugwort leaves is 10-30 seconds, and the water temperature is 4-8°C.

3. The extraction process of a volatile oil from Artemisia argyi according to claim 1, characterized in that: In the pulverizing step, the rotation speed of the pulverizer is 1000-3000 rpm, and the mesh number of the sieve is 50-80 meshes.

4. The extraction process of wormwood volatile oil according to claim 1, characterized in that: In the soaking step, the amount of distilled water added is 6-14 times the volume of the mugwort leaves, and the soaking time is 10-40 minutes.

5. The extraction process of wormwood volatile oil according to claim 1, characterized in that: In the gas-boiling treatment step, the gas outlet surface of the spinneret faces upward, and the air pump ventilates the interior of the container for 10-40 minutes.

6. The extraction process of wormwood volatile oil according to claim 1, characterized in that: In the extraction step, the temperature of the steam when the solution boils is 105° C., and the extraction time is 3-7 hours.

7. The extraction process of wormwood volatile oil according to claim 1, characterized in that: In the material preparation step, the water spinner works for 3-5 minutes, and the rotation speed of the water spinner is 1000-1500 rpm.

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