Electrochemical detection kit and automatic detection device thereof

By designing an electrochemical detection kit and its automatic detection device, the existing electrochemical detection devices are solved, and the problem of low efficiency and low integration in large-scale detection is achieved, and efficient and automated electrochemical detection is achieved, which is suitable for small-scale detection. The organization has improved the testing efficiency and utilization rate of equipment.

CN119310296AInactive Publication Date: 2025-01-14T J BIOTECH TIANJIN
View PDF 0 Cites 0 Cited by

Patent Information

Application Number
CN202411669142.7
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-11-21
Publication Date
2025-01-14
Estimated Expiration
Not applicable · inactive patent

AI Technical Summary

Technical Problem

The existing electrochemical detection devices are low in efficiency, low in integration, and have large space and poor suitability in large-scale detection. Especially in small testing institutions, it is difficult to achieve efficient and automated testing.

Method used

An electrochemical detection kit and its automatic detection device were designed, including an electrochemical detection kit, a sample kit, an electrolyte injection and extraction device, a sample injection device, an electrode detection device, a sample encoding detection device, a cleaning device, and a discharge device. The liquid device, electrode secondary detection device, waste collection box, circuit and gas circuit control device, and automatic lifting device simplifies the electrode detection process through automated and integrated design, and realizes rapid liquid discharge and compact space device layout.

Benefits of technology

It improves the efficiency and integration of electrochemical detection, reduces the burden on operators, saves medical equipment space, is suitable for large-scale inspection, and improves the detection efficiency and equipment utilization rate.

✦ Generated by Eureka AI based on patent content.

Smart Images

  • Figure CN119310296A_ABST
    Figure CN119310296A_ABST
Patent Text Reader

Abstract

The invention discloses an electrochemical detection kit and an automatic detection device thereof, and belongs to the technical field of medical treatment. The working platform is divided into three layers, the first layer is an electrochemical detection kit feeding platform and is located on the uppermost portion of the platform; the second layer is a pretreatment platform, and the middle part of the platform comprises a sample kit, an electrolyte injection and extraction device, a sample coding detection device, an electrode detection device and a sample injection device; the third layer is an electrochemical detection platform which is located on the lowermost layer of the platform and comprises a cleaning device, a drainage device, an electrode secondary detection device, an electrolyte injection device and a waste collection box; the electrochemical detection kit lifting device is positioned on the side of the platform; the electrochemical detection kit is integrated with an electrode detection plug and a waste liquid discharge channel; the circuit and gas circuit control device is arranged at the lowermost part of the platform; the device improves the integration degree of sample detection, and the integrated electrochemical detection kit improves the sample detection efficiency.
Need to check novelty before this filing date? Find Prior Art

Description

Technical Field

[0001] The invention belongs to the field of medical technology, and in particular relates to an electrochemical detection kit and an automatic detection device thereof. Background Art

[0002] Sample testing is often used in the field of medical testing. Routine body fluid testing includes blood testing, urine testing, pleural and abdominal effusion testing, etc. Blood testing can clearly detect a variety of blood indicators such as hemoglobin levels, blood sugar, blood lipids, liver function, kidney function, platelet count and other blood indicators. Urine testing can detect indicators such as urine composition, urine enzymes, and urine protein composition. Pleural and abdominal effusion testing can detect indicators such as protein composition and white blood cell count. Body fluid testing can help doctors diagnose diseases and monitor health conditions.

[0003] Electrochemical detection is used in different fields including medical detection, environmental and gas detection, chemical production and other fields such as measuring blood sugar, active enzymes, sulfur dioxide concentration, etc. Electrochemical sensors can be designed in different styles for different application scenarios. They can be two-electrode or three-electrode, and can be potentiometers, voltammeters or ammeters. Some electrochemical detection sensors are based on organic matter and nano-accessories for detection.

[0004] Different detection indicators in the field of medical testing have different detection modes. According to different detection reagents and different detection bases, different pre-treatments are performed on the test samples. After the test, different equipment is used for post-processing to finally obtain the final detection parameters, which are used as the basis for clinical diagnosis. The essence of electrochemical detection is to convert identifiable features into current signals. There are currently various methods to modify electrochemical sensors. When the electrochemical sensor binds to the target, it will cause changes in the effective aperture of the channel, the inner surface charge, and the inner wall wettability, thereby causing changes in the ion current. The current detection device detects the change in the original current value, thereby detecting the corresponding indicators.

[0005] For general testing departments and institutions, different detection devices are generally configured, different pretreatments are performed according to different test samples, and the tests are performed on the corresponding detection devices. This method is suitable for departments or institutions with sufficient testing space. However, for general testing institutions, due to the small space and complicated pretreatment and testing processes, improper testing is likely to affect the testing efficiency and quality. Most of the existing electrochemical detection devices are single detection devices with complex detection processes and low detection rates, which are not suitable for large-scale electrochemical detection. Based on the above-mentioned electrochemical detection principles and application scenarios, it is necessary to design an electrochemical detection kit and its automatic detection device; the detection device has a high degree of integration, occupies less space, and has a high degree of automation in the pretreatment and detection processes, which is suitable for large-scale testing. Summary of the invention

[0006] In view of the characteristics and application scenarios of electrochemical detection, and the current situation that most existing electrochemical detection devices are for single-person detection, the detection process is complicated, the detection efficiency is low, and the device integration is low, an electrochemical detection kit and an automatic detection device are provided.

[0007] An embodiment of the present invention provides an electrochemical detection kit and an automated detection device thereof, including: an electrochemical detection kit, a sample kit, an electrolyte injection and extraction device, a sample injection device, an electrode detection device, a sample coding detection device, a cleaning device, a drainage device, an electrode secondary detection device, a waste collection box, a circuit and gas path control device, an electrolyte injection device, an automatic lifting device, an automatic lifting platform, an upper platform, a middle platform and a lower platform.

[0008] First aspect:

[0009] The invention provides an electrochemical automatic detection device, including an electrochemical detection kit, an electrolyte injection and extraction device, a sample injection device, an electrode detection device, a sample coding detection device, a cleaning device, a drainage device, an electrode secondary detection device, a waste collection box, a circuit and gas path control device, an automatic lifting device, an upper platform, a middle platform and a lower platform.

[0010] The automatic lifting device is provided with a guide rail parallel to the X-axis, and the automatic lifting platform can move along the guide rail; the upper surface of the automatic lifting platform is provided with a Y-axis guide rail, and the Y-axis guide rail of the automatic lifting platform is consistent with the Y-axis guide rails of the upper platform, the middle platform and the lower platform.

[0011] The working platform is divided into an upper platform, a middle platform and a lower platform. The electrochemical detection kit is located on the upper platform; the electrolyte injection and extraction device, the sample injection device, the sample coding detection device, the electrode detection device and the sample kit are located on the middle platform; the cleaning device, the drainage device, the electrolyte injection device, the electrochemical secondary detection device and the waste collection box are located on the lower platform; the automatic lifting device is located on one side of the upper, middle and lower platforms, and the electrochemical detection kits are transported to the upper, middle and lower platforms through the automatic lifting platform; the waste collection box is located on the other side of the upper, middle and lower platforms and is parallel to the lower platform, and is used to collect the electrochemical detection kit after the detection is completed.

[0012] The electrolyte injection and extraction device is located on the middle platform, including an electrolyte storage tank and an electrolyte pipette for electrolyte injection and extraction. The electrolyte injection and extraction device is fixedly connected to a liftable air path guide parallel to the X-axis; the injection and extraction of the electrolyte, as well as the rise and fall of the air path guide can be achieved through air path control.

[0013] The sample injection device includes a sample injection probe, a guide rail that can move parallel to the Y axis, and a screw structure that can be raised and lowered along the X axis; the sample injection probe is installed with a pipette from the sample reagent box, and extracts the sample from the sample holding device, and finally injects the sample into the detection slot of the electrochemical detection reagent box.

[0014] The electrochemical detection device and the electrochemical secondary detection device can realize translational movement along the Z axis by means of a guide rail parallel to the Z axis installed on the platform. The electrochemical detection device and the electrochemical secondary detection device have multiple electrode detection connectors, and electrical signal detection is realized by inserting the external electrode connector of the electrochemical detection kit.

[0015] The sample test kit includes a waste disposal position, a pipette installation device and a sample holding device. The waste disposal position is located at the rear of the sample test kit, the pipette installation device is located in the middle, and the sample holding device is located in the front. The sample test kit can perform translational movement along the guide rail of the middle platform parallel to the Y-axis.

[0016] The drainage device includes a drainage probe and a drainage duct. The drainage probe can perform translational motion along the air path guide rail parallel to the X-axis; the drainage probe is connected to the circuit and the air path control device, and the extraction effect is achieved by applying negative pressure. The top of the drainage probe is an arc-shaped structure that can match the drainage channel at the bottom of the electrochemical detection kit to achieve sealing and drainage. The number of drainage probes is consistent with the number of detection slots of the electrochemical detection kit; the drainage duct is connected to the circuit and the air path control device to discharge waste liquid.

[0017] Second aspect:

[0018] The present invention provides an electrochemical detection kit and an electrochemical detection method thereof. The electrochemical detection kit comprises a plurality of detection slots, built-in electrodes, external electrode connectors, a sensor placement area, a drain valve and a drain channel. The electrochemical detection kit can be connected to the guide rails of an automatic lifting platform and the guide rails of upper, middle and lower three-layer platforms through a bottom track, thereby realizing translational movement along the Y axis.

[0019] Every two detection slots of the electrochemical detection kit form a group of detection slots. The built-in electrodes are located at both ends of each group of detection slots and are connected to external electrode connectors through built-in wires. Each group of built-in electrodes is connected to an external electrode connector through wires to form a detection circuit.

[0020] The sensor placement area is located between the two detection slots of each group of detection slots. A square slot is provided on the top of the sensor placement area to accommodate the sensor. A circular through hole is opened on the side of the sensor placement area to conduct the current path between the two detection slots.

[0021] The drain valve and drain channel are located at the bottom of each detection tank. The drain valve will only open when negative pressure is applied; and the drain valve is a one-way flow valve, and the flow direction is that the liquid in the detection tank flows through the drain valve to the drain channel.

[0022] The present invention provides an electrochemical testing process including:

[0023] S1: Transport the electrochemical detection kit from the upper platform to the bottom of the electrolyte injection and extraction device on the middle platform, and inject electrolyte into all detection slots.

[0024] S2: The electrode detection device detects the current I0 flowing through the sensor, and the electrochemical detection kit returns to the bottom of the electrolyte injection and extraction device to extract the electrolyte.

[0025] S3: The sample coding detection device scans the sample and encodes it. The sample injection probe is equipped with a pipette. After the sample is sucked up, an equal amount of the sample is injected into each detection slot. After the injection is completed, the waste pipette is moved to the waste disposal position and discarded.

[0026] S4: After the sample contacts the sensor and the reaction is completed, the electrochemical detection kit is transported to the cleaning device and the drainage device on the lower platform. The drainage probe is inserted into the drainage channel to apply negative pressure, and the drainage valve is opened to discharge the sample liquid in the detection tank. The cleaning device injects purified water into the detection tank and performs ultrasonic cleaning. The drainage probe applies negative pressure again to discharge the cleaned wastewater.

[0027] S5: The electrochemical detection kit is moved to the bottom of the electrolyte injection device, the electrolyte injection device injects electrolyte into the detection tank, and the electrode secondary detection device measures the current I1 flowing through the sensor, and enters the data after comparing with I0 to complete the detection process, and sends the electrochemical detection kit after the test to the waste collection box.

[0028] The benefits of the present invention are as follows: through structural innovation of the electrochemical detection kit, built-in electrodes are arranged on both sides of the detection tank, and the external electrode connector is integrated into one side of the detection tank, and the built-in electrodes and the external electrodes are connected through built-in wires to form a current loop, which simplifies the electrode detection process and improves the integration of the electrochemical detection kit, so that the electrode detection device can detect the current without being inserted into the electrolyte, thereby improving the detection efficiency; by arranging a drain valve in the detection tank, the detection tank of the electrochemical detection kit can be quickly drained, reducing the burden on operators; by arranging the upper working platform as the electrochemical detection kit loading platform, the middle platform as the pretreatment platform, and the lower platform as the detection platform, the space of medical equipment is saved, the overall device is made more compact, and the utilization rate and integration level of the equipment are improved. BRIEF DESCRIPTION OF THE DRAWINGS

[0029] Figure 1It is a schematic diagram of the overall structure of the present invention.

[0030] Figure 2 It is a schematic diagram of the structure of the sample kit of the present invention.

[0031] Figure 3 It is a schematic diagram of the structure of the liquid discharge device of the present invention.

[0032] In the figure: 1. electrochemical detection kit; 2. electrode detection probe device; 3. sample injection device; 4. sample kit; 5. sample coding detection device; 6. electrode secondary detection device; 7. waste collection box; 8. drainage device; 9. electrolyte injection device; 10. cleaning device; 11. circuit and gas circuit control device; 12. automatic lifting platform; 13. lower platform; 14. middle platform; 15. electrolyte injection and extraction device; 16. upper platform; 17. automatic lifting device; 21. electrode detection device guide rail; 31. sample probe guide rail; 32. sample injection probe; 41. sample holding device; 42. pipette installation device; 43. waste disposal position; 61. electrode secondary detection device guide rail; 81. drainage probe; 82. drainage catheter; 121. automatic lifting platform guide rail; 131. lower platform guide rail; 141. middle platform guide rail; 161. upper platform guide rail. DETAILED DESCRIPTION

[0033] In order to present the features, advantages and technical solutions of the present invention more clearly and intuitively, the embodiments of the present invention will be explained in full, detail and clarity in combination with the drawings and descriptions of the examples of the present invention. Obviously, the described embodiments are part of the embodiments of the present invention, not all of them. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0034] In the following, in conjunction with the accompanying drawings, an electrochemical detection kit and an automatic detection device thereof provided by an embodiment of the present invention are explained through specific embodiments.

[0035] See also Figure 1 The embodiment of the present invention provides an automatic detection device including 1. an electrochemical detection kit; 2. an electrode detection device; 3. a sample injection device; 4. a sample reagent kit; 5. a sample coding detection device; 6. an electrode secondary detection device; 7. a waste collection box; 8. a drainage device; 9. an electrolyte injection device; 10. a cleaning device; 11. a circuit and gas path control device; 12. an automatic lifting platform; 13. a lower platform; 14. a middle platform; 15. an electrolyte injection and extraction device; 16. a upper platform; 17. an automatic lifting device.

[0036] Specifically, the electrochemical detection kit 1 is used to realize the detection based on the electrochemical sensor. The built-in sensor can be modified by different test samples to detect different indicators such as liver function, kidney function, CA50, alpha-fetoprotein and other indicators. The electrode detection device 2 is used to detect the current flowing through the sensor. At this time, the sensor is not modified by the sample, and the measured current is the initial current. The electrolyte is injected into the detection tank, and the electrode detection device detects and obtains the initial current I0 flowing through the sensor. The sample injection device 3 extracts the sample in the sample reagent box to inject the sample into each detection tank. The sample kit 4 includes a sample holding device 41, a straw installation device 42 and a waste disposal position 43. Specifically, the sample holding device 41 is used to hold the test sample, the straw installation device 42 is used to install the sample straw, and the waste disposal position 43 is used to store the discarded straw. The sample coding detection device 5 is used to encode and record the sample. The electrode secondary detection device 6 is used to detect the current I1 flowing through the sensor after the sample modification. By comparing the difference between I1 and I0, the corresponding detection data can be obtained. The waste collection box 7 is used to collect the electrochemical detection kit 1 after the test is completed. The drainage device 8 is used to extract the sample after the test in the detection tank and to extract the wastewater after the detection tank is cleaned. The electrolyte injection device 9 injects electrolyte into the detection tank after the cleaning is completed to detect the secondary current of the sensor. The cleaning device 10 includes a purified water syringe and an ultrasonic probe for cleaning the detection tank and cleaning the sample residue in the detection tank. The circuit and gas path control device 11 includes accessories such as circuit wires, gas path conduits, air pumps, motors and solenoid valves, and controls the entire detection process through an external processor. The automatic lifting platform 12 can accommodate the electrochemical detection kit 1, and realize the lifting operation under the traction of the automatic lifting device 17, so that the electrochemical detection kit 1 can be moved to different platforms. The lower platform 13 is used to realize the detection process of the sample. The middle platform 14 is used to realize the pretreatment process of the sample. The electrolyte injection and extraction device 15 is used to realize the injection and extraction of electrolyte in the detection tank. The upper platform 16 is used to implement the loading process of the electrochemical detection kit 1. The automatic lifting device 17 is used to realize the operation of raising and lowering the automatic lifting platform, and the automatic lifting device 17 is located on the side of the three-layer platform. The above-mentioned detection units are arranged on the upper platform, the middle platform and the lower platform, and each platform realizes different functions respectively, vertically utilizing the effective space, and through the collaborative operation of different functional modules, the effective utilization of space is realized, and the degree of integration of the detection device is improved.

[0037] The built-in electrodes of the electrochemical detection kit 1 are connected to the external electrode connector via built-in wires, thereby realizing electrode integration and simplifying the detection process. Through the automated and integrated electrochemical detection kit, the detection efficiency is improved and the amount of manual work is reduced.

[0038] See also Figure 1 and Figure 2 The loading device is located on the upper platform 16 and is provided with a guide rail 161 parallel to the X-axis. The electrochemical detection kit 1 can move forward and backward along the guide rail 161 in the X-axis direction to complete the loading operation. The upper platform 16 can place multiple electrochemical detection kits 1 in parallel, thereby achieving the effect of uninterrupted loading. The automatic lifting platform 12 can make a translational movement along the Y-axis under the traction of the automatic lifting device 17. The automatic lifting platform 12 includes a guide rail 121 parallel to the X-axis. The guide rail 121 is consistent with the upper platform guide rail 161. The electrochemical detection kit 1 can move to the guide rail 121 through the guide rail 161 and then reach the middle platform 14 and the lower platform 13 through the traction of the automatic lifting device 17. The electrochemical detection kit 1 can translate along the X-axis and Y-axis through the guide rails. The function of the guide rails is to transfer the electrochemical detection kit 1 to different workstations to complete operations of different processes. The design of the guide rail enables the device to achieve precise displacement and position control in different directions, thereby adapting to the position requirements of different process operations. Programming control of displacement and position can improve the accuracy of equipment operation and reduce errors compared to manual operation. The guide rail under programmed control can achieve multiple precise reciprocating movements, improve work efficiency, reduce human operation resources, improve the stability and accuracy of device operation, and improve overall operating efficiency.

[0039] It should be noted that the upper platform 16 can accommodate multiple electrochemical detection kits 1. The multiple electrochemical detection kits 1 are placed side by side and transported to the automatic lifting platform 12 in sequence through the guide rails, thereby increasing the detection efficiency.

[0040] See also Figure 1 , Figure 2 and Figure 3 , the middle platform 14 is located below the upper platform 16, and the middle platform 14 is provided with a guide rail 141 parallel to the X-axis and a Z-axis guide rail 21 located in the same plane as and perpendicular to the X-axis. The electrochemical detection kit 1 can be moved to the middle platform 14 via the automatic lifting platform 12 to complete the pretreatment process. The electrode detection device 2, the blood sample injection device 3, the sample kit 4, the sample detection encoding device 5 and the electrolyte injection and extraction device 15 are located on the middle platform 14. The electrochemical detection kit 1 first moves to the electrolyte injection and extraction device 15, and the electrolyte pipette injects electrolyte into the detection tank 16 of the electrochemical detection kit. After the injection is completed, the electrochemical detection kit 1 moves along the guide rail 141 to the electrode detection device 2, and the electrode detection connector of the electrode detection device 2 is inserted into the external electrode connector of the electrochemical detection kit 1 for detection. Figure 1The electrode probe 2 shown can perform translational movement along the guide rail 21 parallel to the Z axis, and the electrode detection connector of the electrode detection device 2 can fully cooperate with the external electrode connector of the electrochemical detection kit 1 to measure and record the initial current I0 passing through the sensor. After the measurement is completed, the electrochemical detection kit 1 moves along the guide rail 141 to the electrolyte injection and extraction device 15, and the electrolyte pipette extracts the electrolyte in the detection tank 16. After the extraction is completed, the electrochemical detection kit 1 moves along the guide rail 141 to the sample injection device 3, and the sample injection probe 32 can perform translational movement along the guide rail 31 parallel to the X axis, and can also perform translational movement along the lead screw parallel to the Z axis. The sample injection probe installs the pipette from the pipette installation device 42 of the sample reagent box 4, moves along the guide rail 31 to the top of the sample holding device 41 to be tested, and is translated to below the sample liquid surface by the lead screw to perform extraction operations. After the extraction is completed, it moves to the top of the detection slot of the electrochemical detection reagent box 1 to inject the sample into each detection slot respectively. After the injection is completed, it is translated along the guide rail 31 to the top of the waste disposal position 43 of the sample reagent box 1, and the pipette that completes the extraction and injection operations is discarded at the waste disposal position 43. The electrochemical detection reagent box 1 after the sample is injected moves along the guide rail 141 to the automatic lifting platform 12, and the automatic lifting platform 12 reaches the lower platform 13 under the traction of the automatic lifting device 17. After the sample reagent box 4 completes the sample extraction of all groups, it can be replaced with a new sample reagent box 4, and the pipette waste in the waste material discarding box 43 can be recycled or discarded. By setting a multi-degree-of-freedom sample injection probe to absorb and move samples, the accuracy of sample absorption is improved and the workload of staff is reduced. By integrating the pipette installation device 42, the waste material discarding box 43 and the sample containing device 41 into the sample reagent box 4, the space utilization rate of the device is improved, and the integrated sample reagent box 4 facilitates the collection of discarded pipettes. The process of sucking samples, injecting samples and discarding pipettes can be realized by only translating along the X-axis 31 guide rail and translating along the Z-axis lead screw 32. The programming and operation during use are relatively simple, and there are many applicable scenarios, which improves the degree of automation of detection.

[0041] It should be noted that the sample detection encoding device 5 can enter the patient's basic information into the detection system by scanning the barcode attached to the sample test tube. The basic information includes: the patient's age, gender, name, sample collection time, sample collection source, patient's medical history, sample test items, etc. Registering the patient's basic information by scanning the barcode increases the efficiency and accuracy of information entry compared to traditional manual registration.

[0042] See also Figure 1 , Figure 2 and Figure 3, the lower platform 13 is located below the middle platform 14, and the lower platform 13 is provided with a guide rail 131 parallel to the X-axis and a Z-axis guide rail 61 located in the same plane and perpendicular to the X-axis. The electrochemical detection kit 1 can move along the automatic lifting platform 12 to the lower platform 13 to complete the detection process. The cleaning device 10, the drainage device 8, the electrode secondary detection device 6, the electrolyte injection device 9 and the waste collection box 7 are all located on the lower platform 13. The electrochemical detection kit 1 first moves along the guide rail 131 parallel to the X-axis to the bottom of the cleaning device 10. The cleaning device 10 and the drainage device 8 are located in the same vertical plane, and the drainage device 8 is located below the lower platform. The drainage probe 81 of the drainage device 8 first passes through the circular hole of the lower platform and is inserted into the drainage channel 12 of the electrochemical detection kit. The curved surface of the drainage probe 81 can perfectly match the curved surface of the drainage channel, ensuring the sealing during drainage. The drainage probe 81 sucks the tested sample into the drainage channel 12 by applying negative pressure, and discharges it through the drainage conduit 82 connected to the outside. After the sample is discharged, the cleaning probe of the cleaning device 10 goes deep into the detection tank along the gas path parallel to the Y axis and injects purified water. The ultrasonic probes installed side by side apply ultrasonic waves to the purified water in the detection tank to achieve the cleaning effect. After the cleaning is completed, the drainage device 8 is started again to suck the waste water in the detection tank after cleaning into the external conduit 82 for discharge. After the discharge is completed, the electrochemical detection kit 1 moves along the guide rail 131 to the electrolyte injection device 9, and the electrolyte injection device 9 is inserted into the detection tank along the gas path parallel to the Y axis to inject electrolyte. After the electrolyte is injected, the electrode secondary detection device 6 is inserted into the external electrode connector of the electrochemical detection kit 1 along the guide rail 61 parallel to the Z axis, and the electrical signal I1 is detected and recorded. The required detection index can be obtained by comparing the electrical signals I1 and I0, and finally the electrochemical detection kit 1 after detection is thrown into the waste collection box 7.

[0043] The waste collection box 7 is located below one side of the lower platform 13. After moving to the end via the guide rail 131, it falls into the waste collection box 7, which improves the operating efficiency of the device and can collect waste without manual operation, avoiding possible pollution and the like, thereby enhancing the safety of the device. The drainage probe extracts waste liquid from the bottom, which saves space in the device and avoids possible leakage and the like. The ultrasonic probe of the cleaning device 10 can release ultrasonic waves to achieve a better cleaning effect. A circuit and air path control device 11 is provided below the lower platform. By integrating accessories such as air paths, air pumps, circuits, and solenoid valves into the circuit and air path control device 11, space is effectively saved.

[0044] The above are only examples of the present invention and are not intended to limit the present invention. For those skilled in the art, the present invention may have different modifications and variations. Any modification, conversion, substitution and deformation made within the scope of the principle and spirit of the present invention should be included in the scope of the claims of the present invention.

Claims

1. An electrochemical detection kit and an automatic detection device thereof, characterized in that: It comprises an electrochemical detection kit (1), an electrolyte injection and extraction device (15), a sample injection device (3), an electrode detection device (2), a sample coding detection device (5), a sample kit (4), a cleaning device (10), a liquid discharge device (8), an electrode secondary detection device (6), an electrolyte injection device (9), a waste collection box (7), a circuit and gas path control device (11), an automatic lifting device (17), an upper platform (16), a middle platform (14), a lower platform (13) and an automatic lifting platform (12); The upper platform (16) comprises: an electrochemical detection reagent kit (1); the middle platform (14) comprises: an electrolyte injection and extraction device (15), a sample injection device (3), a sample coding detection device (5), an electrode detection device (2) and a sample reagent kit (4); the lower platform (13) comprises: a cleaning device (10), a liquid discharge device (8), an electrochemical secondary detection device (6) and a waste collection box (7); The automatic lifting device (17) is located on one side of the upper platform (16), the middle platform (14) and the lower platform (13), and comprises an automatic lifting platform (12) and a guide rail parallel to the X-axis; The waste collection box (7) is located on the other side of the upper platform (16), the middle platform (14) and the lower platform (13), and below the lower platform (13); The circuit and gas circuit control device (11) is located below the lower platform (13); Guide rails parallel to the Y-axis are arranged on the surfaces of the upper platform (16), the middle platform (14) and the lower platform (13).

2. An electrochemical detection kit and automatic detection device thereof according to claim 1, characterized in that: The sample reagent box (4) is located on the middle platform (14) and can perform translational movement along a guide rail (141) of the middle platform (14) parallel to the Y axis; the sample reagent box (4) comprises a waste disposal position (43), a pipette installation device (42) and a sample containing device (41), wherein the waste disposal position (43) is located at the rear of the sample reagent box (4), the pipette installation device (42) is located in the middle, and the sample containing device (41) is located at the front.

3. The sample kit (4) according to claim 2, characterized in that: The sample containing device (41) can contain multiple groups of samples, each group of samples containing multiple samples.

4. The electrochemical detection kit and automatic detection device thereof according to claim 1, characterized in that: The upper platform (16) comprises a plurality of electrochemical detection kits (1); the electrochemical detection kits (1) are moved via a guide rail (161) arranged on the upper platform (16) and parallel to the Y axis.

5. The electrochemical detection kit and automatic detection device thereof according to claim 1, characterized in that: The electrolyte injection and extraction device (15) comprises an electrolyte storage tank and an electrolyte suction pipe for electrolyte injection and extraction, wherein the electrolyte suction pipe is fixedly connected to the electrolyte storage tank; The electrolyte storage tank is located above the electrolyte suction pipe and is fixedly connected to a gas path guide rail parallel to the X-axis. An electrolyte filling switch is provided on the top of the electrolyte storage tank. There are a plurality of electrolyte suction pipes, and their arrangement is consistent with the detection tank of the electrochemical detection kit (1). The electrolyte storage tank is connected to the circuit and gas path control device (11) through a conduit.

6. The electrochemical detection kit and automatic detection device thereof according to claim 1, characterized in that: The sample injection device (3) comprises a sample injection probe (32), a guide rail (31) parallel to the Y axis, and a lead screw structure parallel to the X axis.

7. The sample injection probe (32) according to claim 6, characterized in that: The sample injection probe (32) comprises a probe and a straw; the sample injector comprises a plurality of probes, the number of which is consistent with the number of samples contained in each group of the sample containing device (41); and the straw is consistent with the straw of the straw installation device (42).

8. An electrochemical detection kit and automatic detection device thereof according to claim 1, characterized in that: The cleaning device (10) comprises a purified water injector, an ultrasonic probe and a liftable platform parallel to the X-axis; the purified water injectors and ultrasonic probes are of the same number, and the purified water injectors and ultrasonic probes are fixedly connected to the liftable platform.

9. An electrochemical detection kit and automatic detection device thereof according to claim 1, characterized in that: The drainage device (8) comprises a drainage probe (81) and a drainage conduit (82); the drainage conduit (82) is connected to the circuit and the gas circuit control device (11); the top of the drainage probe (81) is an arc-shaped structure consistent with the outer surface contour of the drainage channel at the bottom of the electrochemical detection kit; the number of the drainage probes (81) is consistent with the number of detection slots of the electrochemical detection kit (1).

10. An electrochemical detection kit and automatic detection device thereof according to claim 1, characterized in that: The electrode detection device (2) is located on the middle platform (14), and the electrode secondary detection device (6) is located on the lower platform (13); the electrode detection device (2) and the electrode secondary detection device (6) comprise a plurality of electrode detection connectors; the electrode detection connectors can cooperate with the external electrode connectors of the electrochemical detection kit (1) to form an electrical signal detection circuit.

11. An electrochemical detection kit and automatic detection device thereof according to claim 1, characterized in that: The surface of the automatic lifting platform (12) is provided with a guide rail (121) parallel to the Y axis, and the guide rail (121) is consistent with the guide rails arranged on the surfaces of the layer platform (16), the middle platform (14) and the lower platform (13).