Composition for preventing and treating coronary heart disease and preparation method thereof

By using raw materials such as Chuanxiong, borneol and honey to prepare powders or pills, the problem of complex ingredients and poor treatment effects of traditional Chinese medicine products is solved, effective prevention and treatment of coronary heart disease is achieved, and the production process is simplified and costs are reduced.

CN119318674APending Publication Date: 2025-01-17张晓燕
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Patent Information

Application Number
CN202411500989.2
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-10-25
Publication Date
2025-01-17

AI Technical Summary

Technical Problem

The existing finished Chinese medicines have complex ingredients, poor treatment effects and lack the effect of preventing coronary heart disease.

Method used

Chuanxiong and borneol are used as the main raw materials and combined with honey to prepare into powder or pills. Through the crushing and mixing process, the production process is simplified, and the active ingredients of the raw materials are used to provide a composition that promotes blood circulation, removes blood stasis, calms the mind and wakes up the brain. It is suitable for external use and internal use.

Benefits of technology

It has achieved simplification and cost reduction of drug ingredients, and has significant effects on preventing and treating coronary heart disease. It has refreshed the mind and prevented attacks through the volatile ingredients of the powder, and relieved symptoms in emergencies, providing time for better treatment.

✦ Generated by Eureka AI based on patent content.

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Abstract

The invention provides a composition for treating cerebral anoxia and coronary heart disease and a preparation method thereof, and relates to the field of traditional Chinese medicinal materials. The traditional Chinese medicine composition comprises the following raw materials by weight: 3 qian of ligusticum wallichii and 2 qian of borneol. Comprising the following steps: drying ligusticum wallichii, and pulverizing into powder in a pulverizer; the preparation method comprises the following steps: grinding borneol into powder, uniformly mixing with ligusticum wallichii powder to prepare powder, or adding honey, uniformly stirring, and extruding to prepare pills. The traditional Chinese medicine composition has the effects of promoting blood circulation to remove blood stasis and promoting qi circulation, soothing nerves and restoring consciousness. The traditional Chinese medicine composition can be used for preventing coronary heart disease and relieving sudden course of hypoxia caused by delayed cerebral blood supply, and the situation that the best medical care opportunity is lost due to sudden or lack of timely energy supplement is reduced.
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Description

Technical Field

[0001] The present invention relates to the field of Chinese medicinal materials, and in particular to a composition for preventing and treating coronary heart disease and a preparation method thereof. Background Art

[0002] Coronary heart disease is a type of heart disease characterized by atheromatous coronary arteries, which are narrowed or blocked. Typical symptoms include chest pain and tightness, which worsens after activity. It is more common in people over 40 years old. If coronary heart disease is not effectively controlled, it can easily cause myocardial ischemia and hypoxia, leading to angina pectoris, myocardial infarction, sudden death, etc.

[0003] At present, there are two ways to treat coronary heart disease: drug treatment and surgical treatment. Drug treatment mainly includes lipid-lowering drugs: such as statins, atorvastatin calcium tablets, etc., which are used to control blood lipids and stabilize coronary artery plaques. Antiplatelet drugs: such as aspirin, used to prevent thrombosis. Nitrate drugs: such as nitroglycerin, used to dilate coronary arteries and improve myocardial blood supply. Calcium ion antagonists: such as verapamil, used to increase coronary blood supply and reduce myocardial oxygen consumption. β-blockers: such as metoprolol, used to lower heart rate, reduce myocardial oxygen consumption, and increase coronary blood flow. There are also drugs to improve the myocardium, such as angiotensin-converting enzyme inhibitors. Surgical treatments include coronary intervention and coronary artery bypass grafting.

[0004] In the field of traditional Chinese medicine, the main herbs for treating coronary heart disease include those that promote blood circulation and dissipate blood stasis: salvia miltiorrhiza, peach kernel, safflower, red peony root, Panax notoginseng, etc., which can improve the blood circulation of the heart and brain and relieve symptoms. Qi-tonifying and heart-nourishing herbs: ginseng, astragalus, codonopsis, etc., which help improve heart function and relieve symptoms of coronary heart disease. Warming and promoting heart yang herbs: cinnamon twig, asarum, aconite, etc., which help warm and promote heart yang and improve heart function. Blood-tonifying and yin-nourishing herbs: angelica, raw rehmannia, peony, etc., which can nourish blood and yin and have an auxiliary therapeutic effect on coronary heart disease.

[0005] However, the finished Chinese herbal medicines currently in use have complex ingredients, poor therapeutic effects, and do not have the function of preventing coronary heart disease. Summary of the invention

[0006] The purpose of the present invention is to provide a composition for preventing and treating coronary heart disease, which has the effects of promoting blood circulation, removing blood stasis and promoting qi circulation, calming the nerves and refreshing the brain, and can be used externally and orally to reduce the occurrence of situations in which the best time for medical care is lost due to sudden attacks or lack of timely energy supplementation.

[0007] Another object of the present invention is to provide a method for preparing a composition for preventing and treating coronary heart disease, wherein the raw material is directly crushed into powder, the process is simple, and the effective components of the raw material can be fully utilized. When the powder is taken, it is taken with warm water, so that the medicinal effect can be exerted on the internal organs. When it is combined with honey to make a pill, no water is needed when taking it, and it can be taken by chewing it independently under the premise of clear consciousness.

[0008] The present invention solves the technical problem by adopting the following technical solutions.

[0009] On the one hand, an embodiment of the present invention provides a composition for preventing and treating coronary heart disease, which comprises the following raw materials by weight: 1-5 qian of Chuanxiong and 1-5 qian of borneol.

[0010] In some embodiments of the present invention, 1-5 grams of honey is also included by weight.

[0011] In some embodiments of the present invention, the following raw materials are included by weight: 3 qian of Chuanxiong and 2 qian of Borneol.

[0012] In some embodiments of the present invention, the following raw materials are included by weight: 3 qian of Chuanxiong, 3 qian of borneol, and 3 qian of honey.

[0013] On the other hand, an embodiment of the present invention provides a method for preparing a composition for preventing and treating coronary heart disease, comprising: drying Chuanxiong rhizome, and then crushing it into powder in a crusher; and uniformly mixing it with borneol.

[0014] Alternatively, the Chuanxiong is dried and then crushed into powder in a grinder; borneol is ground into powder, honey is added to the Chuanxiong powder and borneol powder, the mixture is stirred evenly, and then squeezed into pills.

[0015] Compared with the prior art, the embodiments of the present invention have at least the following advantages or beneficial effects:

[0016] The composition provided by the embodiment of the present invention has simple drug ingredients and low cost. It has a certain preventive effect on coronary heart disease. When the disease has not occurred, the powder of the composition can be put into a sachet, and the volatile components in the powder can refresh the mind and prevent the onset of coronary heart disease; when the coronary heart disease suddenly occurs, the powder can be taken to slow down the course of the disease, provide sufficient time to wait for better treatment, and reduce the occurrence of the best medical care opportunity lost due to sudden onset or lack of timely energy supplementation.

[0017] The preparation method provided by the embodiment of the present invention is simple to operate and has low requirements on equipment. The raw materials are directly crushed into powder, which is conducive to the volatilization of the effective ingredients in the raw materials, so that when the sachet containing the powder is worn, it can have an excellent preventive effect; when taken orally, the crushed medicine can be fully absorbed by the body, so that the medicinal power can be exerted in the internal organs and the therapeutic effect is improved. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings required for use in the embodiments are briefly introduced below. It should be understood that the following drawings only show certain embodiments of the present invention and therefore should not be regarded as limiting the scope. For ordinary technicians in this field, other related drawings can be obtained based on these drawings without creative work.

[0019] Figure 1 The powder prepared in Example 1 of the present invention;

[0020] Figure 2 The prepared pills are according to Example 4 of the present invention. DETAILED DESCRIPTION

[0021] In order to make the purpose, technical scheme and advantages of the embodiments of the present invention clearer, the technical scheme in the embodiments of the present invention will be described clearly and completely below. If the specific conditions are not specified in the embodiments, they are carried out according to conventional conditions or conditions recommended by the manufacturer. If the manufacturer of the reagents or instruments used is not specified, they are all conventional products that can be purchased commercially.

[0022] It should be noted that, in the absence of conflict, the embodiments of the present invention and the features in the embodiments may be combined with each other. The present invention will be described in detail below with reference to specific embodiments.

[0023] On the one hand, an embodiment of the present invention provides a composition for preventing and treating coronary heart disease, which comprises the following raw materials by weight: 1-5 qian of Chuanxiong and 1-5 qian of borneol.

[0024] Chuanxiong is mainly used to promote blood circulation, dispel wind and relieve pain. It can improve the blood supply of cardiovascular and cerebrovascular diseases and is a commonly used drug in the clinic for cardiovascular and cerebrovascular diseases. Chuanxiong can be used to treat various symptoms caused by qi stagnation and blood stasis, such as chest pain, chest tightness and shortness of breath. Chuanxiong also has the effects of vasodilation, lowering blood pressure, increasing coronary flow, and improving microcirculation.

[0025] Borneol is mainly used to invigorate the brain and relieve headaches and dizziness caused by cerebral blood vessel blockage. It can also be used to treat hemiplegia and slurred speech caused by sequelae of stroke.

[0026] The formula provided by the present invention adopts a simple combination of entering the qi and blood, so that the Chinese herbal medicine can be better applied in real life through the transformation form of powder or pill, and uses sachets and sachets as carriers, which not only retains beauty and practicality, but also increases the actual medicinal value. Daily wearing can refresh the mind and prevent coronary heart disease. When the disease occurs, the patient can take medicine to alleviate the course of the disease and buy time for rescue.

[0027] Chuanxiong enters both the blood and qi, activates blood circulation and qi, dispels wind and relieves pain, is pungent, warm, and enters the liver, gallbladder, and pericardium meridians. It can ascend to the head. It contains alkaloids, volatile oils, folic acid, visfatin, and vitamin A.

[0028] Borneol, aromatic, awakens the mind and refreshes the brain. Borneol has many sources, one of which is extracted and processed from plants of the Lauraceae family, the main ingredient of which is dextrorotatory borneol, and the other is extracted and processed from the fresh leaves of the Asteraceae plant Blumea balsamifera, the main ingredient of which is l-borneol. Most of the borneol on the market is synthetic, the main ingredient of which is turpentine, camphor, etc. as raw materials, synthesized by chemical methods, also known as machine-made borneol, which contains a large amount of isoborneol.

[0029] Natural borneol is cool, synthetic borneol and moxa slices are slightly cold, the three are pungent, bitter, and enter the heart, spleen, and lung meridians, all of which have the effects of opening the orifices and refreshing the mind, clearing away heat and relieving pain, and are applied to fever, coma, shock, stroke, phlegm deficiency, chest pain, and heartache, and have the effects of opening all the orifices and dispersing stagnant fire. Borneol is pungent, fragrant, and strong, good at dispersing and unblocking, and is very effective for all sudden and violent qi stagnation, phlegm and coma. In the embodiment of the present invention, the borneol used is natural borneol, and the main component is d-borneol or levorotatory borneol.

[0030] In some embodiments of the present invention, 1-5 grams of honey is also included by weight.

[0031] Honey has the effect of relieving fatigue. It has high fructose and glucose content, which is easily absorbed and utilized by the body, and helps to relieve fatigue. Eliminate food stagnation: Honey can promote the normal secretion of gastric acid, enhance intestinal peristalsis, and shorten defecation time. Sober up: The fructose in honey can promote the decomposition and absorption of alcohol, which is conducive to quick sobering up and relieving the headache after drinking. Calm and sleep: The glucose, vitamins, magnesium, phosphorus, and calcium in honey can regulate the function of the nervous system, relieve nervous tension, and promote sleep. In an embodiment of the present invention, honey can not only play its own effect, but also serve as a binder, which is convenient for squeezing Chuanxiong powder and borneol powder into pills.

[0032] In some embodiments of the present invention, the following raw materials are included by weight: 3 qian of Chuanxiong and 2 qian of Borneol.

[0033] In some embodiments of the present invention, the following raw materials are included by weight: 3 qian of Chuanxiong, 3 qian of borneol, and 3 qian of honey.

[0034] On the other hand, an embodiment of the present invention provides a method for preparing a composition for preventing and treating coronary heart disease, which comprises: drying Chuanxiong, crushing it into powder in a crusher, and mixing it evenly with block borneol. Block borneol will become smaller as it evaporates, and the volatilization time of block borneol is long.

[0035] Alternatively, the Chuanxiong is dried and then crushed into powder in a grinder; borneol is ground into powder, honey is added to the Chuanxiong powder and borneol powder, the mixture is stirred evenly, and then squeezed into pills.

[0036] The features and performance of the present invention are further described in detail below in conjunction with the embodiments.

[0037] Example 1

[0038] Prepare the raw materials according to the following ratio:

[0039] Chuanxiong 3 qian, Borneol 2 qian;

[0040] After the rhizome of Chuanxiong is dried, it is crushed into powder in a pulverizer and mixed evenly with borneol to obtain the powder of the present embodiment. When in use, the powder is put into a gauze bag, and then placed in a sachet or a bag with small holes, and carried with you, and the powder is replaced every 2-3 days. The unused powder is sealed and stored.

[0041] Example 2

[0042] Prepare the raw materials according to the following ratio:

[0043] Chuanxiong 3 qian, Borneol 3 qian;

[0044] After the Chuanxiong is dried, it is crushed into powder in a grinder; and mixed evenly with the block-shaped borneol. The powder of this embodiment is obtained. When in use, the powder is put into a gauze bag, and then placed in a sachet or a bag with small holes, and carried with you. The powder is replaced every 2-3 days. Unused powder is sealed and stored.

[0045] Example 3

[0046] Prepare the raw materials according to the following ratio:

[0047] Chuanxiong 3 qian, Borneol 3 qian;

[0048] After the Chuanxiong is dried, it is crushed into powder in a grinder; and mixed evenly with the block-shaped borneol. The powder of this embodiment is obtained. When in use, the powder is put into a gauze bag, and then placed in a sachet or a bag with small holes, and carried with you. The powder is replaced every 2-3 days. Unused powder is sealed and stored.

[0049] Example 4

[0050] Prepare the raw materials according to the following ratio:

[0051] 3 qian of Chuanxiong, 3 qian of borneol, and 3 qian of honey.

[0052] After drying Chuanxiong, crush it into powder in a grinder; grind borneol into powder, mix it evenly with Chuanxiong powder, add honey, stir evenly, squeeze it into a mold, and make it into pills, each about 6-8g. When using, put the pills into the mouth and chew them while the patient is conscious.

[0053] Example 5

[0054] Prepare the raw materials according to the following ratio:

[0055] Chuanxiong 3 qian, Borneol 3 qian, Honey 3 qian

[0056] After drying Chuanxiong, crush it into powder in a grinder; grind borneol into powder, mix it evenly with Chuanxiong powder, add honey, stir evenly, squeeze it into a mold, and make it into pills, each about 6-8g. When using, put the pills into the mouth and chew them while the patient is conscious.

[0057] Example 6

[0058] Prepare the raw materials according to the following ratio:

[0059] Chuanxiong 3 qian, Borneol 3 qian, Honey 3 qian

[0060] After drying Chuanxiong, crush it into powder in a grinder; grind borneol into powder, mix it evenly with Chuanxiong powder, add honey, stir evenly, squeeze it into a mold, and make it into pills, each about 6-8g. When using, put the pills into the mouth and chew them while the patient is conscious.

[0061] Example 7

[0062] Prepare the raw materials according to the following ratio:

[0063] Chuanxiong 3 qian, Borneol 3 qian, Honey 5 qian

[0064] After drying Chuanxiong, crush it into powder in a grinder; grind borneol into powder, mix it evenly with Chuanxiong powder, add honey, stir evenly, squeeze it into a mold, and make it into pills, each about 6-8g. When using, put the pills into the mouth and chew them while the patient is conscious.

[0065] Effect example

[0066] 1. Wang, male, 58 years old, clinically diagnosed with coronary heart disease, occasional heart pain, chest tightness. Wear the powder prepared in Example 1, and change it every 2-3 days. During the wearing period, the number of heart pain and chest tightness symptoms decreased, the mind was clear, the body felt relaxed, and there was no chest tightness after slight exercise.

[0067] 2. Jiang, female, 53 years old, clinically diagnosed with coronary heart disease for more than 2 years, with an average of one attack per month, severe chest tightness, dizziness, and arm pain during the onset. Wear the powder prepared in Example 1 and change it every 2-3 days. During the wearing period, the self-reported body is relaxed, breathing is smooth, and there is no chest tightness. Within 1 year of wearing during the maternity period, the number of attacks has been significantly reduced, and the disease has occurred twice within half a year. Continue to wear it for 1 year, and take the pills of Example 4 once a day. No disease occurred within half a year. Stop the drug and continue to wear the sachet, and no disease occurred in the subsequent half a year.

[0068] In summary, the composition provided by the embodiment of the present invention has simple drug ingredients and low cost. It has a certain preventive effect on coronary heart disease. When the disease does not occur, the powder of the composition can be put into a sachet, and the volatile components in the powder can refresh the mind and prevent the onset of coronary heart disease; when coronary heart disease occurs suddenly, the powder can be taken to slow down the course of the disease, provide sufficient time to wait for better treatment, and reduce the occurrence of the best medical care opportunity due to sudden or lack of timely energy supplementation.

[0069] The preparation method provided by the embodiment of the present invention is simple to operate and has low requirements on equipment. The raw materials are directly crushed into powder, which is conducive to the volatilization of the effective ingredients in the raw materials, so that when the sachet containing the powder is worn, it can have an excellent preventive effect; when taken orally, the crushed medicine can be fully absorbed by the body, so that the medicinal power can be exerted in the internal organs and the therapeutic effect is improved.

[0070] The embodiments described above are part of the embodiments of the present invention, rather than all of the embodiments. The detailed description of the embodiments of the present invention is not intended to limit the scope of the invention claimed for protection, but merely represents selected embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

Claims

1. A composition for preventing and treating coronary heart disease, characterized in that: The following raw materials are included by weight: 1-5 qian of Chuanxiong and 1-5 qian of borneol.

2. The composition for preventing and treating coronary heart disease according to claim 1, characterized in that: Calculated by weight, it also includes 1-5 grams of honey.

3. The composition for preventing and treating coronary heart disease according to claim 1, characterized in that: The following raw materials are included by weight: 3 qian of Chuanxiong and 2 qian of borneol.

4. The composition for preventing and treating coronary heart disease according to claim 2, characterized in that: The following raw materials are included by weight: 3 qian of Chuanxiong, 3 qian of borneol, and 3 qian of honey.

5. A method for preparing a composition for preventing and treating coronary heart disease as claimed in any one of claims 1 or 3, characterized in that: The method comprises drying the rhizome of Chuanxiong, crushing it into powder in a crusher, and uniformly mixing it with borneol.

6. A method for preparing a composition for preventing and treating coronary heart disease as claimed in any one of claims 2 or 4, characterized in that: The method comprises the following steps: drying the rhizome of Chuanxiong and then crushing it into powder in a crusher; grinding borneol into powder, adding honey into the rhizome of Chuanxiong and the borneol powder, stirring evenly, and squeezing the mixture into pills.