Multi-hole-site reference solution preparation instrument

Abstract

The invention discloses a multi-hole-site reference solution preparation instrument, which comprises a preparation box, a placing mechanism, a dissolution promoting monitoring mechanism and a quantitative preparation mechanism, the placing mechanism is used for placing a plurality of reference containers, and the quantitative preparation mechanism is used for quantitatively conveying a solvent in a solvent box into the reference containers; the dissolution promoting monitoring mechanism comprises a plurality of dissolution promoting monitoring assemblies, and the plurality of dissolution promoting monitoring assemblies are arranged; according to the multi-hole-site reference substance solution preparation instrument, the placement mechanism capable of placing a plurality of reference containers is arranged in the preparation box and is matched with the quantitative preparation mechanism for use, so that a solvent in the solvent box can be conveyed into the reference containers in a quantitative and positioned manner; the dissolution promoting monitoring mechanism can heat and oscillate the reference substance solvent in the reference container and then monitor the clarity, in the preparation process, errors caused by different transferring tools and manual judgment are reduced, the problem that the real concentration of the reference substance solvent is biased is solved, and the reference substance solvent is prepared more accurately.

Description

Technical Field

[0001] The invention belongs to the technical field of drug inspection, in particular to a multi-porous reference solution configuration instrument. Background Art

[0002] The accuracy of reference sample configuration is crucial to the results of drug testing. Currently, reference samples are manually prepared and volumetric flasks are used for dilution. If reference sample dilution is involved, a pipette or a pipette gun is often used to pipette and then adjust the volume to the specified volume. However, the accuracy of the reference sample in the entire preparation process is often affected by factors such as the increase in configuration steps, the accuracy of the pipetting tool, and differences in human judgment, resulting in bias in the true concentration of the reference sample. Therefore, in response to the above problems, the present application provides a multi-porous reference sample solution preparation instrument that reduces the errors of different pipetting tools and human judgment while achieving more accurate configuration of reference samples. Summary of the invention

[0003] Purpose of the invention: To provide a multi-porous reference solution preparation instrument, which can achieve more accurate preparation of reference solutions while reducing errors caused by different pipetting instruments and human judgment.

[0004] Technical solution:

[0005] A multi-porous reference solution preparation instrument, comprising a preparation box, a placement mechanism, a dissolution-promoting monitoring mechanism and a quantitative preparation mechanism, wherein the placement mechanism and the dissolution-promoting monitoring mechanism are both arranged in the preparation box, the quantitative preparation mechanism is located above the preparation box and connected to a solvent box arranged on a support platform, the placement mechanism is used to place a plurality of reference containers, the quantitative preparation mechanism quantitatively transports the solvent in the solvent box to the reference containers, the dissolution-promoting monitoring mechanism comprises a plurality of dissolution-promoting monitoring components, and the plurality of dissolution-promoting monitoring components are used to respectively heat, oscillate and monitor the reference solution solvents in the plurality of reference containers;

[0006] The support platform is also provided with a cleaning and recovery mechanism, which is located at one side of the quantitative configuration mechanism. The support platform is connected to the base through a lifting component, and the lifting component drives the support platform to move up and down along the height direction of the configuration box. The base is connected to the bottom of the configuration box through a moving mechanism, and the moving mechanism is used to drive the configuration box to reciprocate under the quantitative configuration mechanism and the cleaning and recovery mechanism, so that after the reference substance solution in the configuration box is configured at the quantitative configuration mechanism, the configuration box moves to the cleaning and recovery mechanism to complete the cleaning operation of the reference container;

[0007] The configuration box is also provided with an air-drying mechanism, and the air-drying component performs an air-drying operation on the control container after the cleaning operation is completed.

[0008] In a further embodiment, the placement mechanism includes a placement plate fixed in the configuration box, the placement plate is provided with a plurality of placement holes for placing control containers, and each of the placement holes is correspondingly provided with one of the dissolution-promoting monitoring components;

[0009] The dissolution-promoting monitoring component includes a heating element, an oscillating element and a solution clarity monitoring element. The heating element is arranged on the inner wall of the placement hole and wrapped around the outside of the control container. The oscillating element is located below the placement hole and adheres to the bottom of the control container. The solution clarity monitoring element is arranged above the placement hole to monitor the reference solvent in the control container.

[0010] In a further embodiment, the quantitative delivery mechanism includes a quantitative delivery pump and a plurality of quantitative delivery pipes, the quantitative delivery pump is fixed on the support platform, the suction end of the quantitative delivery pump extends into the solvent tank, and the delivery end of the quantitative delivery pump is connected to the plurality of quantitative delivery pipes through a first main pipe;

[0011] A plurality of the quantitative delivery tubes are arranged in one-to-one correspondence with a plurality of the control containers, and first solenoid valves are installed at both ends of the quantitative delivery tubes.

[0012] In a further embodiment, the cleaning and recovery mechanism comprises a cleaning water delivery pump and a waste liquid recovery pump, both of which are fixed on the support platform, the suction end of the cleaning water delivery pump and the delivery end of the waste liquid recovery pump extend into the cleaning liquid tank and the waste liquid recovery tank respectively, the delivery end of the cleaning water delivery pump and the suction end of the waste liquid recovery pump are connected to a second main pipe, a cleaning valve and a recovery valve are provided on the second main pipe, the recovery valve is used to control the closing and opening of the waste liquid recovery pump and the second main pipe, and the cleaning valve is used to control the closing and opening of the cleaning and recovery pump and the second main pipe;

[0013] The second main pipe is connected with a plurality of cleaning recovery pipes, and the plurality of cleaning recovery pipes are arranged in one-to-one correspondence with the plurality of control containers. A second solenoid valve is provided at one end of the plurality of cleaning recovery pipes connected with the second main pipe.

[0014] In a further embodiment, the air drying mechanism includes an air supply assembly provided on one side of the outside of the configuration box, a plurality of air drying pipes and a first power member, one end of the plurality of air drying pipes is located in the configuration box and is arranged one-to-one with the plurality of control containers, the other ends of the plurality of air drying pipes all pass through the configuration box to connect to the air supply assembly, the air supply assembly includes a hot air blower and an air supply main pipe, and the air supply main pipe inputs the hot air output by the hot air blower into the plurality of air drying pipes;

[0015] The air drying pipe is in an inverted "L" shape, and includes a vertical air supply part and a transverse connecting part that are interconnected. The transverse connecting part is an accordion-type telescopic structure. The bottom end of the vertical air supply part corresponds to the control container, and the top end is connected to one end of the transverse connecting part. The other end of the transverse connecting part is connected to the air supply main pipe.

[0016] The first power member is connected to the transverse connecting portion to drive the transverse connecting portion to move horizontally along the radial direction of the placement hole above the control container.

[0017] In a further embodiment, the first power member comprises a telescopic electric cylinder, a fixed end of the telescopic electric cylinder is fixed on the configuration box, the telescopic end is connected to a push plate, and the push plate is connected to a plurality of the transverse connecting parts.

[0018] In a further embodiment, the air-drying mechanism further includes a drying component, the drying component is disposed on the inner wall of the configuration box, and the drying component includes a heating tube.

[0019] In a further embodiment, the moving mechanism comprises a moving motor and a moving member, the moving motor is mounted on the base and connected to the configuration box via the moving member;

[0020] The moving part includes a moving nut and a moving lead screw matched with the moving nut. The moving nut is fixedly connected to the bottom of the configuration box. One end of the moving lead screw is installed on the output end of the moving motor, and the other end is rotatably connected to the base.

[0021] In a further embodiment, a sliding connection is provided between the base and the configuration box, and the sliding connection includes a slider installed at the bottom of the configuration box, and the slider slides horizontally in a slide groove opened on the base; the stability of the cover movement and covering can be improved.

[0022] In a further embodiment, a covering mechanism is further provided in the configuration box, the covering mechanism comprising two cover plates symmetrically arranged about the center line of the length direction of the placement plate, the cover plates being connected to a second power member, the second power member driving the two cover plates to move toward each other to cover the top of the control container;

[0023] The second power member includes a power motor and a long rod, the power motor is installed on one side of the inner part of the configuration box, one end of the long rod is connected to the output end of the power motor, and the other end is rotatably connected to the inner wall of the configuration box, the long rod is provided with two threaded areas with opposite screw directions, each of the threaded areas is threadedly sleeved with a threaded moving sleeve, and each of the threaded moving sleeves is fixedly connected to one end of a cover plate;

[0024] The other end of the cover is connected to an auxiliary sliding member, which includes a sliding sleeve installed on the other end of the cover, and the sliding sleeve is arranged on a sliding rod, which is parallel to the long rod and fixed on the other side of the configuration box; an oscillating member can be configured to maintain the stability of the control container.

[0025] Beneficial effects of the present invention:

[0026] (1) By providing a placement mechanism capable of placing a plurality of control containers in the configuration box and cooperating with the quantitative configuration mechanism located above the configuration box, the solvent in the solvent box can be quantitatively positioned and delivered to the corresponding control container through the quantitative configuration mechanism, and the dissolution-promoting monitoring mechanism provided in the configuration box can first heat and oscillate the reference substance solvent in the control container and then monitor whether the clarity of the reference substance solvent meets expectations. In this configuration process, the errors caused by different pipetting instruments and human judgment are reduced, the problem of bias in the actual concentration of the reference substance solvent is reduced, and the reference substance solvent can be configured more accurately.

[0027] (2) A cleaning and recovery mechanism is also provided on one side of the quantitative configuration mechanism. When the configuration box completes the configuration operation, the moving mechanism on the base operates to move the configuration box to the cleaning and recovery mechanism. The cleaning and recovery mechanism can clean the control container. There is no need to manually take out the control container and clean it separately. This is more convenient and the efficiency is effectively improved. BRIEF DESCRIPTION OF THE DRAWINGS

[0028] Figure 1 It is a right side cross-sectional structural schematic diagram of the present invention.

[0029] Figure 2 It is a left side structural schematic diagram of the present invention.

[0030] Figure 3 It is a schematic diagram of the partial cross-sectional structure of the front side of the present invention.

[0031] Figure 4 The present invention Figure 1 Enlarged structural diagram at A in the middle.

[0032] Figure 5 The present invention Figure 3 Enlarged structural diagram at B in the middle.

[0033] Figure 6 It is a schematic diagram of the top view structure of the configuration box of the present invention.

[0034] Figure 7 It is a schematic structural diagram of the right side of the present invention under the solvent delivery state.

[0035] Figure 8 It is a schematic diagram of the top view of the support platform of the present invention.

[0036] Fig. 9 It is a schematic diagram of the top view of the base structure of the present invention.

[0037] The figures are marked as follows: configuration box 1, placement plate 2, placement hole 21, control container 22, heating element 23, oscillating element 24, solution clarity monitoring element 25, quantitative conveying mechanism 3, solvent box 31, support platform 4, lifting assembly 41, cleaning and recovery mechanism 5, cleaning liquid box 51, waste liquid recovery box 52, base 6, moving mechanism 61, sliding connection 62, air-drying mechanism 7, air-drying pipe 71, air supply assembly 72, first power element 73, drying element 8, covering mechanism 9, cover plate 91, second power element 92, auxiliary sliding element 93. DETAILED DESCRIPTION

[0038] In the following description, a large number of specific details are provided to provide a more thorough understanding of the present invention. However, it is apparent to those skilled in the art that the present invention can be implemented without one or more of these details. In other examples, in order to avoid confusion with the present invention, some technical features well known in the art are not described.

[0039] The present invention is further described in detail below in conjunction with the accompanying drawings.

[0040] Reference Figure 1-9, is a multi-porous reference solution preparation instrument disclosed in the present invention, comprising a preparation box 1, a placement mechanism, a dissolution-promoting monitoring mechanism and a quantitative preparation mechanism, wherein the placement mechanism and the dissolution-promoting monitoring mechanism are both arranged in the preparation box 1, the quantitative preparation mechanism is located above the preparation box 1 and is connected to a solvent box 31 arranged on a support table 4, the placement mechanism is used to place a plurality of control containers 22, the quantitative preparation mechanism quantitatively transports the solvent in the solvent box 31 to the control container 22 to obtain a reference solution solvent, the dissolution-promoting monitoring mechanism comprises a plurality of dissolution-promoting monitoring components, and the plurality of dissolution-promoting monitoring components are used to heat, oscillate and monitor the reference solution solvents in the plurality of control containers 22 respectively; a cleaning and recovery mechanism 5 is also provided on the support table 4, the cleaning and recovery mechanism 5 Located on one side of the quantitative configuration mechanism, the support platform 4 is connected to the base 6 through a lifting component 41, and the lifting component 41 drives the support platform 4 to move up and down along the height direction of the configuration box 1. The lifting component 41 includes a lifting electric cylinder, and the base 6 is connected to the bottom of the configuration box 1 through a moving mechanism 61. The moving mechanism 61 is used to drive the configuration box 1 to move back and forth under the quantitative configuration mechanism and the cleaning and recovery mechanism 5, so that after the reference product solution in the configuration box 1 is configured at the quantitative configuration mechanism, the configuration box 1 moves to the cleaning and recovery mechanism 5 to complete the cleaning operation of the control container 22; the configuration box 1 is also provided with an air-drying mechanism 7, and the air-drying component performs an air-drying operation on the control container 22 after the cleaning operation is completed.

[0041] The placement mechanism includes a placement plate 2 fixed in the configuration box 1, and a plurality of placement holes 21 for placing control containers 22 are provided on the placement plate 2, and each of the placement holes 21 is correspondingly provided with a dissolution-promoting monitoring component; the dissolution-promoting monitoring component includes a heating element 23, an oscillating element 24 and a solution clarity monitoring element 25, the heating element 23 is arranged on the inner wall of the placement hole 21 and wrapped around the outer side of the control container 22, the oscillating element 24 is located below the placement hole 21 and adheres to the bottom of the control container 22, the solution clarity monitoring element 25 is arranged above the placement hole 21 for monitoring the reference substance solvent in the control container 22, the heating element 23 includes a heating ring, the oscillating element 24 includes a vortex oscillator, the solution clarity monitoring element 25 includes a camera, the heating element 23 , the oscillating element 24 and the solution clarity monitoring element 25 are all electrically connected to the background control system, so that the control signal can be obtained, and then the use parameters of each component can be adjusted according to different needs. For poorly soluble or high-concentration reference substances, a heating module is selected, and the heating template is used to control the heating element 23, and the heating temperature and time can be set. The oscillation module is selected to control the oscillating element 24, and then the oscillation frequency and time can be set, so that the reference substance is fully dissolved in the solution. The solution clarity monitoring module controls the solution clarity monitoring element 25 to perform clarity detection on the configured reference substance solution. According to the results, it can be judged whether the reference substance is completely dissolved, whether there are undissolved fine particles, that is, invisible to the naked eye, and whether the solution is a homogeneous system, that is, whether the clarity values ​​of each part of the solution are consistent, so as to judge the degree of solubility of the reference substance solution.

[0042] The quantitative delivery mechanism 3 includes a quantitative delivery pump and a plurality of quantitative delivery pipes, the quantitative delivery pump is fixed on the support platform 4, the suction end of the quantitative delivery pump extends into the solvent tank 31, and the delivery end of the quantitative delivery pump is connected to the quantitative delivery pipes through the first main pipe; the plurality of quantitative delivery pipes are arranged in a one-to-one correspondence with the plurality of control containers 22, and the first solenoid valves are installed at both ends of the quantitative delivery pipes. According to the configuration requirements, the quantitative delivery pump first absorbs a certain amount of solvent in the solvent tank 31, and then the quantitative delivery pipe of the control container 22 that needs to be configured is connected to the first main pipe at one end. The first solenoid valve is opened, so that the solvent in the first main pipe enters the quantitative delivery pipe according to the configuration. The first main pipe is in an inverted "T" shape. At this time, the first solenoid valve at one end of the quantitative delivery pipe facing the control container 22 is in a closed state. According to the configuration requirements, when a certain amount of solvent is transported into one or more quantitative delivery pipes, the lifting assembly 41 drives the support platform 4 to descend until the lower part of the quantitative delivery pipe enters the control container 22. At this time, the first solenoid valve in the closed state is opened, so that the solvent enters the control container 22 from the quantitative delivery pipe, thereby preventing the solvent from splashing to the outside when flowing out of the quantitative delivery pipe.

[0043] The cleaning and recovery mechanism 5 includes a cleaning water delivery pump and a waste liquid recovery pump, both of which are fixed on the support platform 4, the suction end of the cleaning water delivery pump and the delivery end of the waste liquid recovery pump extend into the cleaning liquid tank 51 and the waste liquid recovery tank 52 respectively, the delivery end of the cleaning water delivery pump and the suction end of the waste liquid recovery pump are connected to the second main pipe, the second main pipe is provided with a cleaning valve and a recovery valve, the recovery valve is used to control the closing and opening of the waste liquid recovery pump and the second main pipe, the cleaning valve is used to control the closing and opening of the cleaning and recovery pump and the second main pipe; the second main pipe is connected with a plurality of cleaning and recovery pipes, the plurality of cleaning and recovery pipes are arranged in a one-to-one correspondence with the plurality of control containers 22, and a plurality of cleaning and recovery pipes are connected to the second main pipe. A second solenoid valve is provided at each end, and the second main pipe is in the shape of an "I". When the control container 22 needs to be cleaned, after the configuration box 1 is moved to the bottom of the cleaning recovery mechanism 5, the support table 4 descends, so that the cleaning recovery pipe approaches and enters the control container 22, and the cleaning valve and the cleaning water delivery pump are opened, and the second solenoid valve on the cleaning recovery pipe of the control container 22 that needs to be cleaned is also opened, so that the cleaning water delivery pump inputs the cleaning liquid in the cleaning liquid tank 51 into the control container 22 through the cleaning recovery pipe opened at the corresponding position to complete the cleaning operation, and then the cleaning water delivery pump and the cleaning valve are closed, and the waste liquid recovery pump and the recovery valve are opened. The waste liquid recovery pump can absorb the waste liquid after cleaning and recover it into the waste liquid recovery box 52 through the cleaning recovery pipe that opens the second solenoid valve, and then the support table 4 rises, and the control container 22 completes the cleaning operation.

[0044] The air-drying mechanism 7 includes an air supply assembly 72, a plurality of air-drying pipes 71 and a first power member 73, which are arranged on one side of the outside of the configuration box 1. One end of the plurality of air-drying pipes 71 is located in the configuration box 1 and is arranged one-to-one with the plurality of control containers 22. The other ends of the plurality of air-drying pipes 71 all pass through the configuration box 1 and are connected to the air supply assembly 72. The air supply assembly 72 includes a hot air blower and an air supply main pipe. The air supply main pipe inputs the hot air output by the hot air blower into the plurality of air-drying pipes 71. An opening and closing solenoid valve is arranged between each air-drying pipe 71 and the air supply main pipe. Selecting to open the opening and closing solenoid valve can connect the air-drying pipe 71 at the corresponding position with the air supply main pipe. The air-drying pipe 71 is in an inverted "L" shape. 1 comprises a vertical air supply part and a transverse connecting part which are interconnected, the transverse connecting part is an accordion-type telescopic structure, the bottom end of the vertical air supply part corresponds to the control container 22, the top end is connected to one end of the transverse connecting part, and the other end of the transverse connecting part is connected to the air supply main pipe; the first power member 73 is connected to the transverse connecting part to drive the transverse connecting part to move horizontally along the radial direction of the placement hole 21 above the control container 22. When cleaning is completed, the first power member 73 drives the transverse connecting part to extend close to the control container 22 until the bottom end of the vertical air supply part corresponds to the top of the control container 22, and then the hot air blower and the opening and closing solenoid valve at the corresponding position are turned on to complete the heating and air-drying operation of the control container 22 by delivering hot air.

[0045] The first power member 73 includes a telescopic electric cylinder, a fixed end of which is fixed on the configuration box 1, and the telescopic end is connected to a push plate, and the push plate is connected to a plurality of the transverse connecting parts. When the telescopic electric cylinder is extended or retracted, the push plate can simultaneously drive a plurality of air-drying pipes 71 to complete the telescopic movement. When performing cleaning, recovery and quantitative configuration, the telescopic electric cylinder shrinks to the minimum position. At this time, the air-drying pipe 71 is away from the symmetrical container and will not hinder the descending quantitative delivery pipe and the cleaning and recovery pipe.

[0046] The air-drying mechanism 7 also includes a drying member 8, which is arranged on the inner wall of the configuration box 1. The drying member 8 includes a heating tube, which can be turned on during the air-drying operation to improve the efficiency of heating and air-drying.

[0047] The moving mechanism 61 includes a moving motor and a moving part, the moving motor is installed on the base 6 and connected to the configuration box 1 through the moving part; the moving part includes a moving nut and a moving screw rod cooperating with the moving nut, the moving nut is fixedly connected to the bottom of the configuration box 1, one end of the moving screw rod is installed on the output end of the moving motor, and the other end is rotatably connected to the base 6. When the moving motor is running, the moving screw rod rotates and drives the moving nut and the configuration box 1 to move along the length direction of the moving screw rod to complete the configuration cleaning operation.

[0048] A sliding connection 62 is also provided between the base 6 and the configuration box 1. The sliding connection 62 includes a slider installed at the bottom of the configuration box 1. The slider slides horizontally in a slide groove opened on the base 6. The sliding direction and sliding range of the slider in the slide groove are consistent with the moving direction and moving range of the moving nut on the moving screw rod.

[0049] A covering mechanism 9 is also provided in the configuration box 1, and the covering mechanism 9 includes two cover plates 91 symmetrically arranged about the center line of the length direction of the placement plate 2, and the cover plates 91 are connected to a second power member 92, and the second power member 92 drives the two cover plates 91 to move toward each other to cover the top of the control container 22, and a flexible rubber layer is provided on the side of the cover plate 91 facing the top of the control container 22, so that when the cover plate 91 is translated to the top of the control container 22, it will not produce excessive friction with it, and the sealing performance is also good. The sum of the areas of the two cover plates 91 is equal to the area of ​​the placement plate 2, so that when they are moved toward each other and close to closing, they can completely cover and close a number of placement holes 21, thereby improving the stability of the control container 22 during the oscillation process; the second power member 92 includes a power motor and a long rod, and the power motor is installed on one side of the interior of the configuration box 1, one end of the long rod is connected to the output end of the power motor, and the other end is rotatably connected to the inner wall of the configuration box 1, so that The long rod is provided with two threaded areas with opposite thread directions, and each of the threaded areas is threadedly sleeved with a threaded movable sleeve, and each of the threaded movable sleeves is fixedly connected to one end of a cover plate 91; the other end of the cover plate 91 is connected to an auxiliary sliding member 93, and the auxiliary sliding member 93 includes a sliding sleeve installed at the other end of the cover plate 91, and the sliding sleeve is slidingly sleeved on the sliding rod, and the sliding rod is parallel to the long rod and fixed on the other side of the configuration box 1. After the solvent enters the control container 22, the support platform 4 is raised, and the power motor is operated, so that the two cover plates 91 move toward each other until the two cover plates 91 are closed on the top of the control container 22 to facilitate the shaking operation, and because the cover plates 91 are arranged below the solution clarity monitoring member 25 and the air drying pipe 71, when the two cover plates 91 are unfolded and moved to the maximum opposite position, the solution clarity monitoring member 25 can monitor the solvent in the control container 22, and the movement of the air drying pipe 71 will not interfere with the unfolded cover plates 91.

[0050] The implementation principle of the present invention is: the solute is first added to the corresponding control container 22, and then the quantitative delivery mechanism 3 is opened, so that the solvent in the solvent box 31 is quantitatively transferred to the quantitative delivery pipe at the corresponding position, the lifting component 41 is operated to make the support platform 4 descend, the quantitative delivery pipe approaches the control container 22 and the solvent is input into the control container 22, and the heating element 23 and the vibration element 24 are turned on to heat and vibrate the solute and the solvent to improve the configuration efficiency, and then the solvent is monitored and identified by the solution clarity monitoring element 25. After the configuration is completed, the configuration box 1 is moved to the cleaning and recovery mechanism 5 by the moving mechanism 61, and the support platform 4 is lowered again, and the control container 22 is first cleaned by the cleaning and recovery mechanism 5 and then the waste liquid after cleaning is recovered.

[0051] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

[0052] The preferred embodiments of the present invention are described in detail above in conjunction with the accompanying drawings. However, the present invention is not limited to the specific details in the above embodiments. Within the technical concept of the present invention, various equivalent transformations can be made to the technical scheme of the present invention, and these equivalent transformations all belong to the protection scope of the present invention.

Claims

1. A multi-porous reference solution preparation instrument, characterized in that: It includes a configuration box, a placement mechanism, a dissolution-promoting monitoring mechanism and a quantitative configuration mechanism, wherein the placement mechanism and the dissolution-promoting monitoring mechanism are both arranged in the configuration box, the quantitative configuration mechanism is located above the configuration box and connected to a solvent box arranged on a support table, the placement mechanism is used to place a plurality of control containers, the quantitative configuration mechanism quantitatively transports the solvent in the solvent box to the control containers, the dissolution-promoting monitoring mechanism includes a plurality of dissolution-promoting monitoring components, and the plurality of dissolution-promoting monitoring components are used to respectively heat, oscillate and monitor the reference substance solvents in the plurality of control containers; The support platform is also provided with a cleaning and recovery mechanism, which is located at one side of the quantitative configuration mechanism. The support platform is connected to the base through a lifting component, and the lifting component drives the support platform to move up and down along the height direction of the configuration box. The base is connected to the bottom of the configuration box through a moving mechanism, and the moving mechanism is used to drive the configuration box to reciprocate under the quantitative configuration mechanism and the cleaning and recovery mechanism, so that after the reference substance solution in the configuration box is configured at the quantitative configuration mechanism, the configuration box moves to the cleaning and recovery mechanism to complete the cleaning operation of the reference container; The configuration box is also provided with an air-drying mechanism, and the air-drying component performs an air-drying operation on the control container after the cleaning operation is completed.

2. A multi-porous reference solution preparation instrument according to claim 1, characterized in that: The placement mechanism comprises a placement plate fixed in the configuration box, the placement plate is provided with a plurality of placement holes for placing control containers, and each of the placement holes is correspondingly provided with a dissolution-promoting monitoring component; The dissolution-promoting monitoring component includes a heating element, an oscillating element and a solution clarity monitoring element. The heating element is arranged on the inner wall of the placement hole and wrapped around the outside of the control container. The oscillating element is located below the placement hole and adheres to the bottom of the control container. The solution clarity monitoring element is arranged above the placement hole to monitor the reference solvent in the control container.

3. The multi-porous reference solution preparation instrument according to claim 1, characterized in that: The quantitative delivery mechanism comprises a quantitative delivery pump and a plurality of quantitative delivery pipes, wherein the quantitative delivery pump is fixed on the support platform, the suction end of the quantitative delivery pump extends into the solvent tank, and the delivery end of the quantitative delivery pump is connected to the plurality of quantitative delivery pipes through a first main pipe; A plurality of the quantitative delivery tubes are arranged in one-to-one correspondence with a plurality of the control containers, and first solenoid valves are installed at both ends of the quantitative delivery tubes.

4. A multi-porous reference solution preparation instrument according to claim 1, characterized in that: The cleaning and recovery mechanism comprises a cleaning water delivery pump and a waste liquid recovery pump, both of which are fixed on the support platform, the suction end of the cleaning water delivery pump and the delivery end of the waste liquid recovery pump extend into the cleaning liquid tank and the waste liquid recovery tank respectively, the delivery end of the cleaning water delivery pump and the suction end of the waste liquid recovery pump are connected to a second main pipe, a cleaning valve and a recovery valve are provided on the second main pipe, the recovery valve is used to control the closing and connection of the waste liquid recovery pump and the second main pipe, and the cleaning valve is used to control the closing and connection of the cleaning and recovery pump and the second main pipe; The second main pipe is connected with a plurality of cleaning recovery pipes, and the plurality of cleaning recovery pipes are arranged in one-to-one correspondence with the plurality of control containers. A second solenoid valve is provided at one end of the plurality of cleaning recovery pipes connected with the second main pipe.

5. The multi-porous reference solution preparation instrument according to claim 1, characterized in that: The air-drying mechanism includes an air supply assembly arranged on one side of the outside of the configuration box, a plurality of air-drying pipes and a first power member, one end of the plurality of air-drying pipes is located in the configuration box and is arranged one-to-one with the plurality of control containers, the other ends of the plurality of air-drying pipes all penetrate the configuration box and are connected to the air supply assembly, the air supply assembly includes a hot air blower and an air supply main pipe, and the air supply main pipe inputs the hot air output by the hot air blower into the plurality of air-drying pipes; The air drying duct is in an inverted "L" shape, and comprises a vertical air supply portion and a transverse connecting portion which are interconnected, wherein the transverse connecting portion is an accordion-type telescopic structure, wherein the bottom end of the vertical air supply portion corresponds to the control container, and the top end is connected to one end of the transverse connecting portion, and the other end of the transverse connecting portion is connected to the air supply main pipe; The first power member is connected to the transverse connecting portion to drive the transverse connecting portion to move horizontally along the radial direction of the placement hole above the control container.

6. A multi-porous reference solution preparation instrument according to claim 5, characterized in that: The first power member comprises a telescopic electric cylinder, a fixed end of the telescopic electric cylinder is fixed on the configuration box, the telescopic end is connected to a push plate, and the push plate is connected to a plurality of the transverse connecting parts.

7. A multi-porous reference solution preparation instrument according to claim 5, characterized in that: The air-drying mechanism further comprises a drying component, which is arranged on the inner wall of the configuration box and comprises a heating tube.

8. The multi-porous reference solution preparation instrument according to claim 1, characterized in that: The moving mechanism includes a moving motor and a moving part, wherein the moving motor is installed on the base and connected to the configuration box through the moving part; The moving part includes a moving nut and a moving lead screw matched with the moving nut. The moving nut is fixedly connected to the bottom of the configuration box. One end of the moving lead screw is installed on the output end of the moving motor, and the other end is rotatably connected to the base.

9. A multi-porous reference solution preparation instrument according to claim 8, characterized in that: A sliding connection is also provided between the base and the configuration box. The sliding connection comprises a sliding block installed at the bottom of the configuration box. The sliding block slides horizontally in a sliding groove provided on the base.

10. The multi-porous reference solution preparation instrument according to claim 1, characterized in that: A covering mechanism is also provided in the configuration box, and the covering mechanism includes two cover plates symmetrically arranged about the center line of the length direction of the placement plate, and the cover plates are connected to a second power member, and the second power member drives the two cover plates to move toward each other to cover the top of the control container; The second power member includes a power motor and a long rod, the power motor is installed on one side of the inner part of the configuration box, one end of the long rod is connected to the output end of the power motor, and the other end is rotatably connected to the inner wall of the configuration box, the long rod is provided with two threaded areas with opposite screw directions, each of the threaded areas is threadedly sleeved with a threaded moving sleeve, and each of the threaded moving sleeves is fixedly connected to one end of a cover plate; The other end of the cover plate is connected with an auxiliary sliding member, which includes a sliding sleeve installed at the other end of the cover plate, and the sliding sleeve is arranged on a sliding rod, and the sliding rod is parallel to the long rod and fixed on the other side of the configuration box.

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