Composition for improving dark skin color and resisting wrinkles as well as preparation method and application of composition

Abstract

The invention discloses a composition for improving dark skin color and resisting wrinkles as well as a preparation method and application of the composition. The composition comprises the following components in percentage by mass: 2%-4% of an emulsifier, 20%-25% of grease, 5%-7% of a first anti-wrinkle agent, 2.5%-13.5% of a second anti-wrinkle agent, 5%-8% of polyol, 9%-12% of a coloring agent, 1%-4% of a filling agent, 0.5%-1.5% of a preservative and the balance of water, wherein the total mass of the composition is 100%; the filling agent comprises mica, silica, pearl powder and lauroyl lysine; the first anti-wrinkle agent comprises a first component and a second component, the first component comprises one or more of sucrose acetate isobutyrate, bio-saccharide gum and pullulan, and the second component comprises trimethylsiloxy silicate ester. The composition for improving the dark skin color and resisting the wrinkles has the effect of nourishing the skin while improving the anti-dark effect and the makeup maintaining effect of base makeup.

Description

Technical Field

[0001] The present application relates to the field of cosmetics, and in particular to a composition for improving dull skin tone and anti-wrinkle, and a preparation method and application thereof. Background Art

[0002] At present, the problems with base makeup mainly focus on increasing the makeup lasting time and brightening the skin tone. The above problems can be solved to a certain extent by increasing the content of artificial synthetic colorants and artificial synthetic film-forming agents in the formula, but long-term use of the base makeup with the above formula will lead to clogged pores, acne, and sweating, which will lead to skin aging and dull skin tone. In addition, by increasing the content of artificial synthetic colorants, whitening effects can be achieved, but it will make it difficult to completely remove makeup or require multiple makeup removals, causing secondary damage to the skin. Therefore, how to make the base makeup have both the effects of lasting makeup and nourishing the skin is a technical problem that needs to be solved urgently. Summary of the invention

[0003] The embodiments of the present application provide a composition for improving dull skin tone and anti-wrinkle, a preparation method and application thereof, which can enhance the anti-dullness effect and makeup-lasting effect of base makeup while also having the effect of nourishing the skin.

[0004] In the first aspect, the embodiments of the present application propose a composition for improving dull skin color and anti-wrinkle. Taking the total mass of the composition as 100%, the composition includes the following components: 2%-4% emulsifier, 20%-25% oil, 5%-7% first anti-wrinkle agent, 2.5%-13.5% second anti-wrinkle agent, 5%-8% polyol, 9%-12% colorant, 1%-4% filler, 0.5%-1.5% preservative, and the balance is water; the filler includes mica, silica, pearl powder and lauroyl lysine; the first anti-wrinkle agent includes a first component and a second component, the first component includes one or more of sucrose acetate isobutyrate, biosaccharide gum and pullulan, and the second component includes trimethylsiloxysilicate.

[0005] According to one aspect of an embodiment of the present application, the mass ratio of the first component to the second component is (0.5-9):(0.5-3), and can be optionally (1-9):(1-2).

[0006] According to one aspect of the embodiment of the present application, the first component includes sucrose acetate isobutyrate, biosaccharide gum and pullulan.

[0007] According to one aspect of the embodiments of the present application, the mass ratio of sucrose acetate isobutyrate, biosaccharide gum and pullulan is (0.5-3): (0.5-4): (0.5-1).

[0008] According to one aspect of the embodiment of the present application, the second anti-wrinkle agent includes galactosidase fermentation broth and Changbai Mountain ginseng extract.

[0009] According to one aspect of the embodiments of the present application, the mass ratio of galactosidase fermentation broth to Changbai Mountain ginseng extract is (4-10): (1-2).

[0010] According to one aspect of the embodiment of the present application, the filler includes mica and lauroyl lysine.

[0011] According to one aspect of an embodiment of the present application, the mass ratio of mica to lauroyl lysine is (1-3): (1-2).

[0012] According to one aspect of an embodiment of the present application, the mass ratio of the first anti-wrinkle agent to the second anti-wrinkle agent is (5.5-6.8):(3-12).

[0013] According to one aspect of an embodiment of the present application, the emulsifier includes one or more of sorbitan sesquioleate, cetyl PEG / PPG-10 / 1 dimethicone, polyglyceryl-2 diisostearate, PEG / PPG-18 / 18 dimethicone and lauryl PEG-10 tri(trimethylsiloxy)silylethyl dimethicone.

[0014] According to one aspect of an embodiment of the present application, the oil includes one or more of cyclopentasiloxane, isohexadecane, caprylyl polymethicone, trimethyl pentaphenyl trisiloxane, caprylic / capric triglyceride and dipentaerythritol hexahydroxystearate / hexastearate / hexarosinate.

[0015] According to one aspect of the embodiment of the present application, the polyol includes one or more of glycerol, butylene glycol, propylene glycol and dipropylene glycol.

[0016] According to one aspect of the embodiment of the present application, the colorant includes one or more of CI 77891, CI 77499, CI 77492 and CI77491.

[0017] According to one aspect of the embodiment of the present application, the preservative includes phenoxyethanol.

[0018] In a second aspect, the present application provides a method for preparing a composition for improving dull skin tone and anti-wrinkle according to the first aspect of the present application, comprising performing multiple homogenization treatments on the components of the composition for improving dull skin tone and anti-wrinkle, wherein the multiple homogenization treatments include:

[0019] Mixing an emulsifier, oil, colorant and filler, and performing a first homogenization process to obtain a first mixture;

[0020] The obtained first mixture is mixed with a first anti-wrinkle agent, a polyol, a preservative, and water, and subjected to a second homogenization treatment to obtain a second mixture;

[0021] The obtained second mixture is mixed with the second anti-wrinkle agent, and then subjected to a third homogenization treatment to obtain a composition for improving dull skin tone and anti-wrinkle.

[0022] According to another aspect of the embodiment of the present application, the temperature of the first homogenization treatment is 75-85° C., the rotation speed of the first homogenization treatment is 12000-14000 rpm, and the time of the first homogenization treatment is 4-6 min.

[0023] According to another aspect of the embodiment of the present application, the temperature of the second homogenization treatment is 60-70° C., the rotation speed of the second homogenization treatment is 7000-9000 rpm, and the time of the second homogenization treatment is 2.5-3.5 min.

[0024] According to another aspect of the embodiment of the present application, the temperature of the third homogenization treatment is 10-40° C., the rotation speed of the third homogenization treatment is 9500-10500 rpm, and the time of the third homogenization treatment is 1-2 min.

[0025] In a third aspect, the embodiments of the present application propose the use of the composition of the first aspect of the present application, or the composition for improving dull skin tone and anti-wrinkle prepared by the preparation method of the second aspect of the present application in cosmetics.

[0026] The embodiment of the present application adds a specific amount of the first anti-wrinkle agent and the second anti-wrinkle agent to the composition, and the anti-wrinkle effect can be improved by the mutual cooperation of the first anti-wrinkle agent and the second anti-wrinkle agent. The first anti-wrinkle agent includes a first component and a second component, the first component includes one or more of sucrose acetate isobutyrate, biosaccharide gum and pullulan, and the second component includes trimethylsiloxysilicate. The first component and the second component cooperate with each other to increase the makeup-lasting effect while making the skin feel less tight, and also enhance the instant anti-wrinkle effect. Fillers are added to the composition, and the fillers include mica, silica, pearl powder and lauroyl lysine. By adding the above fillers at the same time, dullness of the skin can be reduced. By compounding components such as oils, colorants, and fillers in the composition, the anti-dullness effect and makeup-lasting effect of the product can be further improved, and it has the effect of nourishing the skin. BRIEF DESCRIPTION OF THE DRAWINGS

[0027] The features, advantages and technical effects of exemplary embodiments of the present application will be described below with reference to the accompanying drawings.

[0028] Figure 1 Schematic diagram of the preparation method of the present invention;

[0029] Figure 2 This is a test chart of the anti-dullness effect of Example 1 (from left to right: the subject's base, 0 hours after applying makeup, and 8 hours after applying makeup);

[0030] Figure 3This is the anti-dullness effect test diagram of Example 2 (from left to right: the subject's base, 0 hours after applying makeup, and 8 hours after applying makeup);

[0031] Figure 4 This is the anti-dullness effect test diagram of Example 3 (from left to right: the subject's base, 0 hours after applying makeup, and 8 hours after applying makeup);

[0032] Figure 5 This is the anti-dullness effect test diagram of Example 4 (from left to right: the subject's base, 0 hours after applying makeup, and 8 hours after applying makeup);

[0033] Figure 6 This is the anti-dullness effect test diagram of Example 5 (from left to right: the subject's base, 0 hours after applying makeup, and 8 hours after applying makeup);

[0034] Figure 7 This is the anti-dullness effect test chart of Comparative Example 3 (from left to right: the subject's base, 0 hours after applying makeup, and 8 hours after applying makeup);

[0035] Figure 8 This is the anti-dullness effect test chart of Comparative Example 4 (from left to right: the subject's base, 0 hours after applying makeup, and 8 hours after applying makeup);

[0036] Fig. 9 It is a microscopic picture of cells cultured in the culture medium containing galactose yeast fermentation liquid and Changbai Mountain ginseng extract at 0h (scale bar is 100μm);

[0037] Fig.10 It is a microscopic picture of cells cultured in the culture medium containing galactose yeast fermentation liquid and Changbai Mountain ginseng extract for 24 hours (the scale bar is 100 μm);

[0038] Fig.11 It is a microscopic picture of cells cultured in the culture medium without galactose yeast fermentation liquid and Changbai Mountain ginseng extract at 0 h (scale bar is 100 μm);

[0039] Fig.12 It is a microscopic picture of cells cultured in the culture medium without galactose yeast fermentation liquid and Changbai Mountain ginseng extract for 24 hours (scale bar is 100 μm);

[0040] Fig.13 Microscope images of β-galactosidase staining experiments of HSF cells in galactose-free yeast fermentation broth and Changbai Mountain ginseng extract culture broth (the left scale is 250 μm, and the right scale is 100 μm);

[0041] Fig.14 The microscope images of the β-galactosidase staining experiment of HSF cells containing galactose yeast fermentation broth and Changbai Mountain ginseng extract culture broth (the left scale is 250μm, and the right scale is 100μm);

[0042] Fig.15 It is a bar graph of the clinical wrinkle width measurement results of Examples 1-7 and Comparative Examples 1-2. DETAILED DESCRIPTION

[0043] The features and exemplary embodiments of various aspects of the present application will be described in detail below. In the detailed description below, many specific details are proposed to provide a comprehensive understanding of the present application. However, it is obvious to those skilled in the art that the present application can be implemented without the need for some of these specific details. The following description of the embodiments is only to provide a better understanding of the present application by illustrating examples of the present application. In the accompanying drawings and the following description, at least some of the known structures and technologies are not shown to avoid unnecessary ambiguity in the present application; and, for clarity, the size of some structures may be exaggerated. In addition, the features, structures or characteristics described below may be combined in one or more embodiments in any suitable manner.

[0044] It should be noted that, in this application, the terms "first", "second", etc. are used to distinguish similar objects, and are not used to describe a specific order or sequence. Moreover, the term "comprising" or any other variant thereof is intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also includes other elements not explicitly listed, or also includes elements inherent to such process, method, article or device. In the absence of further restrictions, the elements defined by the sentence "comprising..." do not exclude the existence of other identical elements in the process, method, article or device including the elements.

[0045] Unless otherwise specified, the values ​​of the parameters mentioned in this application can be measured by various measurement methods commonly used in the art (for example, they can be tested according to the methods given in the examples of this application). Unless otherwise specified, the test temperature of the parameters mentioned in this application is 25° C. and the test pressure is standard atmospheric pressure.

[0046] A list of items connected by the term "one or more of" may mean any combination of the listed items. The term "plurality" means more than two.

[0047] Bright, young and healthy skin is the pursuit of every beauty lover. With the increase of life pressure and age, the skin color gradually darkens, brown spots and fine lines appear, resulting in a dull face and poor complexion. People hope that cosmetics have multiple functions. In the related art, one liquid foundation has the effect of removing acne while maintaining makeup, and another liquid foundation has the effect of nourishing the skin while increasing the effect of makeup. However, anti-dullness cosmetics only have the effect of anti-dullness, and do not have the effect of nourishing the skin, which cannot meet the needs of consumers for base makeup.

[0048] The present application embodiment proposes a composition for improving dull skin color and anti-wrinkle. The composition comprises the following components based on the total mass of the composition as 100%: 2%-4% emulsifier, 20%-25% oil, 5%-7% first anti-wrinkle agent, 2.5%-13.5% second anti-wrinkle agent, 5%-8% polyol, 9%-12% colorant, 1%-4% filler, 0.5%-1.5% preservative, and the balance is water;

[0049] Fillers include mica, silica, pearl powder, and lauroyl lysine;

[0050] The first anti-wrinkle agent includes a first component and a second component, the first component includes one or more of sucrose acetate isobutyrate, biosaccharide gum and pullulan, and the second component includes trimethylsiloxysilicate.

[0051] The embodiment of the present application adds a specific amount of the first anti-wrinkle agent and the second anti-wrinkle agent to the composition, and the anti-wrinkle effect can be improved by the mutual cooperation of the first anti-wrinkle agent and the second anti-wrinkle agent. The first anti-wrinkle agent includes a first component and a second component, the first component includes one or more of sucrose acetate isobutyrate, biosaccharide gum and pullulan, and the second component includes trimethylsiloxysilicate. The first component and the second component cooperate with each other to increase the makeup-lasting effect while making the skin feel less tight, and also enhance the instant anti-wrinkle effect. Fillers are added to the composition, and the fillers include mica, silica, pearl powder and lauroyl lysine. By adding the above fillers at the same time, dullness of the skin can be reduced. By compounding components such as oils, colorants, fillers, etc. in the composition for improving dull skin color and anti-wrinkle, the anti-dullness effect and base makeup lasting effect of the product can be further improved, and it has the effect of nourishing the skin.

[0052] In some optional embodiments, the mass ratio of the first component to the second component may be (0.5-9):(0.5-3), or optionally (1-9):(1-2).

[0053] The first component is a film-forming agent for the soft film component, and the second component is a film-forming agent for the hard film component. By adjusting the mass ratio of the first component to the second component within the above range, the first component and the second component can be made to cooperate with each other, that is, the soft film component and the hard film component cooperate with each other. The hard film component has a strong ability to prevent scratches, but it is brittle and not foldable. The soft film component is softer, more adherent and foldable. The combined use of the two film-forming agents can make the makeup more natural and form a breathable film on the skin surface, effectively reducing the makeup from falling off due to oiliness, sweating or external environment in summer, and increasing the makeup lasting effect.

[0054] In some optional embodiments, the first component may include sucrose acetate isobutyrate, biosaccharide gum and pullulan.

[0055] The embodiment of the present application can form a soft natural film on the skin surface by selecting the above-mentioned first component, and can absorb moisture in the air and lock it on the skin surface, making the skin feel less tight. It can also enhance the instant anti-wrinkle effect by cooperating with the second component.

[0056] In some optional embodiments, the mass ratio of sucrose acetate isobutyrate, biosaccharide gum and pullulan can be (0.5-3): (0.5-4): (0.5-1).

[0057] By setting the mass ratio of sucrose acetate isobutyrate, biosaccharide gum and pullulan within the above range, sucrose acetate isobutyrate, biosaccharide gum and pullulan can be better matched to further enhance the instant anti-wrinkle effect.

[0058] In some optional embodiments, the second anti-wrinkle agent may include galactosaccharomyces fermentation broth and Changbai Mountain ginseng extract.

[0059] The first anti-wrinkle agent in the embodiment of the present application is an instant anti-wrinkle agent, and its anti-wrinkle principle is physical anti-wrinkle. The second anti-wrinkle agent is a long-acting anti-wrinkle agent. The Changbai Mountain ginseng extract is rich in a large number of polysaccharides, flavonoids, alkaloids and other active substances. Polysaccharides can stimulate fibroblast proliferation, thereby promoting the synthesis of collagen, making the skin firmer and more elastic. Galacto-saccharomyces galactosus fermentation broth contains a large number of small molecule amino acids, polyphenols and other active substances, which have good antioxidant, moisturizing, cell proliferation and other effects. In addition, galacto-saccharomyces galactosus contains a variety of antioxidants, which can inhibit the process of skin aging, slow down the speed of wrinkles and age spots on the skin, and small molecule active substances can more easily penetrate the bottom layer of the skin to exert their effects. The two substances complement each other and are applied to base makeup products. Long-term use has an effective anti-wrinkle effect, achieving the effect of nourishing the skin with makeup.

[0060] In some optional embodiments, the mass ratio of the galactosidase fermentation broth to the Changbai Mountain ginseng extract may be (4-10): (1-2).

[0061] The embodiment of the present application can further nourish the skin and achieve a long-lasting anti-wrinkle effect by setting the mass ratio of galactose yeast fermentation liquid and Changbai Mountain ginseng extract within the above range.

[0062] In some alternative embodiments, the filler may include mica and lauroyl lysine.

[0063] The embodiment of the present application compounds mica with lauroyl lysine, and the natural flaky powder can effectively increase the glossiness of the skin, reduce the volatilization of skin moisture, and improve the skin's moisturizing ability, thereby significantly enhancing the anti-dullness effect of the composition.

[0064] In some optional embodiments, the mass ratio of mica to lauroyl lysine can be (1-3): (1-2).

[0065] In the embodiment of the present application, by setting the mass ratio of mica to lauroyl lysine within the above range, the glossiness of the skin can be improved, and the anti-dullness effect of the composition can be further enhanced.

[0066] In some optional embodiments, the mass ratio of the first anti-wrinkle agent to the second anti-wrinkle agent may be (5.5-6.8):(3-12).

[0067] By setting the mass ratio of the first anti-wrinkle agent to the second anti-wrinkle agent within the above range, the first anti-wrinkle agent and the second anti-wrinkle agent can be better matched to further enhance the immediate anti-wrinkle effect and the long-lasting anti-wrinkle effect.

[0068] In some optional embodiments, the emulsifier may include one or more of sorbitan sesquioleate, cetyl PEG / PPG-10 / 1 dimethicone, polyglyceryl-2 diisostearate, PEG / PPG-18 / 18 dimethicone, and lauryl PEG-10 tris(trimethylsiloxy)silylethyl dimethicone.

[0069] In some optional embodiments, the oil may include one or more of cyclopentasiloxane, isohexadecane, caprylyl polymethicone, trimethyl pentaphenyl trisiloxane, caprylic / capric triglyceride and dipentaerythritol hexahydroxystearate / hexastearate / hexarosinate.

[0070] In some optional embodiments, the polyol may include one or more of glycerol, butylene glycol, propylene glycol, and dipropylene glycol.

[0071] In some optional embodiments, the colorant may include one or more of CI 77891, CI 77499, CI 77492 and CI77491.

[0072] In some optional embodiments, the preservative may include phenoxyethanol.

[0073] Through its antimicrobial activity, phenoxyethanol can inhibit or even eliminate large doses of Gram-positive and Gram-negative microorganisms, and has a significant inhibitory effect on a variety of common bacteria such as Escherichia coli and Staphylococcus aureus.

[0074] Figure 1 Schematic diagram of the preparation method of the present application example, as shown in Figure 1 As shown, the present application embodiment proposes a method for preparing a composition for improving dull skin tone and anti-wrinkle, comprising performing multiple homogenization treatments on the components of the composition, and the multiple homogenization treatments include the following steps:

[0075] S10: mixing the emulsifier, the oil, the colorant and the filler, and performing a first homogenization process to obtain a first mixture;

[0076] S20: mixing the obtained first mixture with the first anti-wrinkle agent, polyol, preservative, and water, and performing a second homogenization treatment to obtain a second mixture;

[0077] S30: After mixing the obtained second mixture with the second anti-wrinkle agent, a third homogenization treatment is performed to obtain a composition for improving dull skin tone and anti-wrinkle.

[0078] The embodiments of the present application can make the composition more evenly dispersed by subjecting each component to multiple homogenization treatments, which is beneficial to the effectiveness of each component in the composition, so that the composition can enhance the anti-dullness effect while also having the effect of nourishing the skin.

[0079] In some optional embodiments, the temperature of the first homogenization process may be 75-85° C., the rotation speed of the first homogenization process may be 12000-14000 rpm, and the time of the first homogenization process may be 4-6 min.

[0080] By adjusting one or more of the temperature, rotation speed or time of the first homogenization treatment within the above range, the colorant and the oil can be mixed more evenly, that is, the colorant is dispersed more evenly in the oil, so that the colorant is more firmly in the system, and the anti-dullness effect is further improved. A homogeneous and fine powder can also be obtained, the specific surface area of ​​the powder is increased, and the mixing of the first mixture is made more uniform, thereby increasing the fit of the colorant to the skin, making the makeup last longer, and not prone to floating powder or sticking powder.

[0081] It should be noted that the treatment temperature of the first homogenization treatment is relatively high, the homogenization speed is relatively fast, and the time of the first homogenization treatment should be controlled within a relatively long time. Because if the time of the first homogenization treatment is too short, the dispersion effect of the colorant in the oil will be poor. Prolonging the time of the first homogenization treatment appropriately is conducive to better grinding of the colorant, so that the dispersion effect of the colorant in the oil is better, thereby helping to improve the anti-dullness effect of the product.

[0082] In some optional embodiments, the temperature of the second homogenization process may be 60-70° C., the rotation speed of the second homogenization process may be 7000-9000 rpm, and the time of the second homogenization process may be 2.5-3.5 min.

[0083] By adjusting one or more of the temperature, rotation speed or time of the second homogenization treatment within the above range, the water phase can be emulsified and mixed, and high-speed homogenization can reduce the demulsification phenomenon of the system. In addition, the oil and water can be fully mixed to form an ultra-microemulsion, and the average particle size of the microemulsion can be adjusted between 10-15nm, which is conducive to the microemulsion entering the skin better, bringing in the active substances, and better exerting the efficacy.

[0084] It should be noted that the homogenization time of the second homogenization treatment is relatively short, thereby reducing the damage to the structure of the film-forming agent.

[0085] In some optional embodiments, the temperature of the third homogenization process may be 10-40° C., the rotation speed of the third homogenization process may be 9500-10500 rpm, and the time of the third homogenization process may be 1-2 min.

[0086] By adjusting one or more of the temperature, rotation speed or time of the third homogenization treatment within the above range, the substances that are easy to agglomerate in the powder can be dispersed into the system, improving the performance of the substance and increasing the makeup-lasting effect. At the same time, high-speed homogenization can reduce the particle size of the substance, making it easier to be absorbed by the skin and achieving the effect of nourishing the skin. The third homogenization treatment mixes the oil phase, the water phase and the active substance, disperses the substances that are easy to agglomerate in the powder into the system, and after mixing evenly, acts more fully and evenly on the face, improving the performance of the substance and increasing the makeup-lasting effect. At the same time, high-speed homogenization reduces the particle size of the substance, making it easier to be absorbed by the skin and achieving the effect of nourishing the skin.

[0087] The embodiments of the present application propose a composition for improving dull skin tone and anti-wrinkle, or the use of the composition for improving dull skin tone and anti-wrinkle prepared by the preparation method of the present application in cosmetics.

[0088] The specific state of the cosmetics in the embodiments of the present application can be solid, liquid or pressurized liquid, and of course can also be made into cream, gel or powder. Cosmetics include but are not limited to liquid foundation, BB cream, contouring liquid, contouring pen, or other base makeup and color makeup systems.

[0089] Example

[0090] The following examples describe the disclosure of the present application in more detail, and these examples are for illustrative purposes only, as various modifications and variations within the scope of the disclosure of the present application are apparent to those skilled in the art. Unless otherwise stated, all parts, percentages, and ratios reported in the following examples are by mass, and all reagents used in the examples are commercially available or synthesized according to conventional methods and can be used directly without further treatment, and the instruments used in the examples are commercially available.

[0091] Example 1

[0092] The components and contents of the composition of Example 1 are shown in Table 1.

[0093] Table 1

[0094]

[0095]

[0096] The preparation method is as follows:

[0097] Phase A: emulsifier, oil and phase C: colorant, filler are mixed, heated to 80°C, stirred at a speed of 13500 rpm for 5 min, and subjected to a first homogenization treatment to obtain a first mixture;

[0098] The obtained first mixture is mixed with phase B: the first anti-wrinkle agent, polyol, preservative, and water, heated to 65° C., stirred at a speed of 8000 rpm for 3 minutes, and subjected to a second homogenization treatment to obtain a second mixture;

[0099] After the obtained second mixture is mixed with phase D: the second anti-wrinkle agent, the temperature is lowered to room temperature 25°C, the stirring speed is 10000 rpm, the time is 2 minutes, and the third homogenization treatment is performed to obtain a composition for improving dull skin color and anti-wrinkle.

[0100] Example 2

[0101] The components and contents of the composition of Example 2 are shown in Table 2.

[0102] Table 2

[0103]

[0104]

[0105] Example 3

[0106] The components and contents of the composition of Example 3 are shown in Table 3.

[0107] Table 3

[0108]

[0109] Example 4

[0110] The components and contents of the composition of Example 4 are shown in Table 4.

[0111] Table 4

[0112]

[0113] Example 5

[0114] The components and contents of the composition of Example 5 are shown in Table 5.

[0115] Table 5

[0116]

[0117]

[0118] Example 6

[0119] Except for sucrose acetate isobutyrate, biosaccharide gum, pullulan, and trimethylsiloxysilicate in a mass ratio of 4:4.5:1:0.5, the remaining ingredients in the composition and the preparation method are the same as those in Example 2.

[0120] Example 7

[0121] Except for sucrose acetate isobutyrate, biosaccharide gum, pullulan, and trimethylsiloxysilicate in a mass ratio of 7:1:1:1, the remaining ingredients in the composition and the preparation method are the same as those in Example 2.

[0122] Comparative Example 1

[0123] The remaining components and preparation method of the composition are the same as those of Example 2, except that the composition and content of the first anti-wrinkle agent in the composition are different, that is, the first anti-wrinkle agent is trimethylsiloxysilicate.

[0124] Comparative Example 2

[0125] Except that the composition and content of the first anti-wrinkle agent in the composition are different, the first anti-wrinkle agent is sucrose acetate isobutyrate, biosaccharide gum, and pullulan, and the mass ratio is 4:3:3. The remaining ingredients and preparation method of the composition are the same as those in Example 2.

[0126] Comparative Example 3

[0127] The composition and the preparation method of the composition are the same as those in Example 2 except that the composition and the content of the filler in the composition are different, the filler is silica, pearl powder, and lauroyl lysine, and the mass ratio is 2:2:6.

[0128] Comparative Example 4

[0129] The composition and the preparation method of the composition are the same as those of Example 2 except that the composition and the content of the filler in the composition are different, the filler is mica, silica, and pearl powder, and the mass ratio is 7:2:1.

[0130] Comparative Example 5

[0131] Except that only one homogenization treatment is performed in the preparation method, all the components of the composition are mixed according to the contents in Table 2 of Example 2, and then treated according to the following treatment conditions: heating to 65° C., stirring speed of 5000 rpm, and time for 10 minutes.

[0132] Comparative Example 6

[0133] In addition to the preparation method, only two homogenization treatments are performed. The conditions of the first homogenization treatment are as follows: the emulsifier, oil, colorant, filler, and first anti-wrinkle agent are mixed, heated to 80° C., stirred at a speed of 5000 rpm, and stirred for 7 minutes to obtain a first mixture. The conditions of the second homogenization treatment are as follows: the first mixture obtained is mixed with polyol, preservative, second anti-wrinkle agent, and water, heated to 55° C., stirred at a speed of 7000 rpm, and stirred for 3 minutes. The composition of the composition is the same as that of Example 2.

[0134] Test Section

[0135] (1) Anti-dullness effect test

[0136] The subjects used the product on their entire face. Before using the product, and at 0h and 8h after using the product, the subjects' facial images were taken, analyzed using Antera 3D's own software, and photographed for record. The subjects lived a normal life with makeup on during the entire test process. Each follow-up visit required the subjects to sit quietly in a constant temperature and humidity room with a temperature of 21±1℃ and a relative humidity of 50±10% for 20 minutes.

[0137] (2) Anti-wrinkle efficacy test

[0138] Cellular Anti-Wrinkle Efficacy Test

[0139] HSF cell scratch assay:

[0140] 1. HDF-α cells were revived and cultured in DMEM medium containing 10% FBS;

[0141] 2. Digest the cells with 0.25% trypsin, and inoculate 24-well plates with 1×104 cells / well in DMEM containing 10% FBS as the culture medium, with a total volume of 500 μL, and culture in a 37°C, 5% CO2 incubator for 24 h;

[0142] 3. After culturing in an incubator (37°C, 5% CO2) for 24 hours, use a 200 μL pipette tip to scratch a "lesion" on a 24-well plate, wash the cells three times with PBS, and remove the scratched cells;

[0143] 4. Dilute the sample with culture medium to the concentration to be tested, place in an incubator (37°C, 5% CO2) and culture for 24 hours. Set up 3 parallels for each group.

[0144] 5. Use an inverted microscope to take photos of each group of migrating cells.

[0145] HSF cell β-galactosidase staining experiment

[0146] 1. Resuscitation of fibroblasts HDF-a, cultured in DMEM medium containing 10% FBS;

[0147] 2. Digest the cells with 0.25% trypsin, and inoculate 24-well plates with 1×104 cells / well in DMEM containing 10% FBS as the culture medium, with a total volume of 500 μL, and culture in a 37°C, 5% CO2 incubator for 24 h;

[0148] 3. Observe cell growth under a microscope;

[0149] 4. Experimental grouping: The experiment needs to set up a blank control group (no H2O2 stimulation), a negative control group (H2O2 stimulation), a positive control group (H2O2 stimulation + vitamin C) and a sample group (H2O2 stimulation + sample). Each group has 4 replicate wells and incubated in a 37°C, 5% CO2 incubator for 24 hours;

[0150] The configuration table is shown in Table 6.

[0151] Table 6

[0152]

[0153] 5. Remove the cell culture medium, wash once with PBS, add 100 μL of β-Gal fixative, and fix at room temperature for 15 minutes;

[0154] 6. Remove the cell fixative and wash the cells 3 times with 1X PBS, 3 minutes each time. Then use reagent (E): β-Gal staining solution C instead of PBS for washing and incubation;

[0155] 7. Prepare the staining working solution according to the proportion. Aspirate the β-Gal cleaning solution and add 1 ml of staining working solution to each well;

[0156] 8. Incubate at 37°C overnight. You can seal the plate with a sealing film or plastic wrap to prevent evaporation.

[0157] Observe under an ordinary optical microscope. If it is not possible to observe and count in time, remove the staining working solution, add 2ml PBS, and store at 2-8℃ for several days;

[0158] (3) Immediate anti-wrinkle clinical effect test

[0159] The subjects used the product on their entire face. The softplus device measured the width of the subjects' wrinkles before and at 0h, 4h, 8h, and 12h after using the product. The subjects lived a normal life with makeup on during the entire test. Each time the subjects returned for a visit, they had to sit quietly in a constant temperature and humidity room with a temperature of 21±1℃ and a relative humidity of 50±10% for 20 minutes.

[0160] The emulsion state test results of Example 2 and Comparative Examples 5-6 are shown in Table 7.

[0161] Table 7

[0162] Serial number Moisture Emulsion fineness Emulsion gloss Fit Comparative Example 5 - - - - Comparative Example 6 - + + - Example 2 ++ ++ ++ ++

[0163] In Table 7: “—” is not good, “+” is good, and “++” is very good.

[0164] The above results show that multiple homogenization treatments can obtain a composition with moderate viscosity, finer texture, better glossiness and better overall color development than single or double homogenization treatments.

[0165] The wrinkle width reduction rates of the subjects in Examples 1-7 at 4h, 8h, and 12h are shown in Table 8.

[0166] Table 8

[0167]

[0168] Note: The wrinkle width reduction rate / % of the subjects at different times is (the wrinkle width of the subjects at time 0 - the wrinkle width of the subjects during the test) / the wrinkle width of the subjects at time 0 × 100%.

[0169] From Examples 1-5, Comparative Examples 3-4 and Figure 2-8 The test results show that Examples 1-5 correspond to Figure 2-6 After 8 hours of wearing the product, the face shows a bright and soft luster, corresponding to the comparison of 3-4 Figure 7-8 After 8 hours of applying the product, the face became noticeably dull and gray. This shows that the combination of mica and lauroyl lysine has a good anti-dullness effect, and the lack of any one ingredient will reduce the anti-dullness effect of the combination.

[0170] Depend on Figure 9-12 The test results show that the galactose yeast fermentation broth and Changbai Mountain ginseng extract in the composition have the effect of promoting cell proliferation and repairing damaged cells.

[0171] Depend on Figure 13-14 The test results show that the combination of galactose yeast fermentation broth and Changbai Mountain ginseng extract has a good anti-wrinkle effect from the cellular level.

[0172] Although the hard film component trimethylsiloxysilicate in the formula of comparative example 1 can instantly resist wrinkles, it makes the skin feel tight after applying makeup, and many subjects said that the makeup feels poor and uncomfortable. The soft film formers sucrose acetate isobutyrate, biosaccharide gum, and pullulan in the formula of comparative example 2 cannot reduce the width of wrinkles in a short time. Therefore, the composition adopts the first component and the second component to make the two film formers complement each other, achieve instant anti-wrinkle effect, and at the same time have a good skin feel, which can meet the needs of applying makeup for a day.

[0173] It should be noted that the present application is not limited to the above-mentioned embodiments. The above-mentioned embodiments are only examples, and the embodiments having the same structure as the technical idea and the same effect as the technical solution of the present application are all included in the technical scope of the present application. In addition, without departing from the scope of the main purpose of the present application, various modifications that can be thought of by those skilled in the art to the embodiments and other methods of combining some of the constituent elements in the embodiments are also included in the scope of the present application.

Claims

1. A composition for improving dull skin tone and anti-wrinkle, characterized in that: Based on the total mass of the composition being 100%, the composition comprises the following components: 2%-4% of an emulsifier, 20%-25% of oil, 5%-7% of a first anti-wrinkle agent, 2.5%-13.5% of a second anti-wrinkle agent, 5%-8% of a polyol, 9%-12% of a colorant, 1%-4% of a filler, 0.5%-1.5% of a preservative, and the balance being water; The fillers include mica, silica, pearl powder and lauroyl lysine; The first anti-wrinkle agent comprises a first component and a second component, wherein the first component comprises one or more of sucrose acetate isobutyrate, biosaccharide gum and pullulan, and the second component comprises trimethylsiloxysilicate.

2. The composition according to claim 1, characterized in that The mass ratio of the first component to the second component is (0.5-9):(0.5-3), and can be optionally (1-9):(1-2).

3. The composition according to claim 1, characterized in that The first component includes sucrose acetate isobutyrate, biosaccharide gum and pullulan; Optionally, the mass ratio of sucrose acetate isobutyrate, biosaccharide gum and pullulan is (0.5-3):(0.5-4):(0.5-1).

4. The composition according to claim 1, characterized in that The second anti-wrinkle agent includes galactosidase fermentation liquid and Changbai Mountain ginseng extract; Optionally, the mass ratio of the galactose yeast fermentation broth to the Changbai Mountain ginseng extract is (4-10): (1-2).

5. The composition according to claim 1, characterized in that The fillers include mica and lauroyl lysine; Optionally, the mass ratio of the mica to the lauroyl lysine is (1-3): (1-2).

6. The composition according to claim 1, characterized in that The mass ratio of the first anti-wrinkle agent to the second anti-wrinkle agent is (5.5-6.8):(3-12).

7. The composition according to claim 1, characterized in that The components in the composition satisfy one or more of the following conditions (1)-(5): (1) The emulsifier includes one or more of sorbitan sesquioleate, cetyl PEG / PPG-10 / 1 dimethicone, polyglyceryl-2 diisostearate, PEG / PPG-18 / 18 dimethicone, and lauryl PEG-10 tris(trimethylsiloxy)silylethyl dimethicone; (2) The oil comprises one or more of cyclopentasiloxane, isohexadecane, octyl polymethicone, trimethyl pentaphenyl trisiloxane, caprylic / capric triglyceride and dipentaerythritol hexahydroxystearate / hexastearate / hexarosinate; (3) The polyol includes one or more of glycerol, butylene glycol, propylene glycol and dipropylene glycol; (4) The colorant includes one or more of CI 77891, CI 77499, CI 77492 and CI 77491; (5) The preservative includes phenoxyethanol.

8. A method for preparing the composition for improving dull skin color and anti-wrinkle according to any one of claims 1 to 7, characterized in that: The method comprises subjecting the components of the composition to multiple homogenization treatments, wherein the multiple homogenization treatments include: The emulsifier, the oil, the colorant and the filler are mixed and subjected to a first homogenization process to obtain a first mixture; The obtained first mixture is mixed with a first anti-wrinkle agent, a polyol, a preservative, and water, and subjected to a second homogenization treatment to obtain a second mixture; The obtained second mixture is mixed with the second anti-wrinkle agent, and then subjected to a third homogenization treatment to obtain a composition for improving dull skin tone and anti-wrinkle.

9. The preparation method according to claim 8, characterized in that: The multiple homogenization processes satisfy one or more of the following conditions (1)-(3): (1) The temperature of the first homogenization treatment is 75-85° C., the speed of the first homogenization treatment is 12000-14000 rpm, and the time of the first homogenization treatment is 4-6 min; (2) The temperature of the second homogenization treatment is 60-70° C., the speed of the second homogenization treatment is 7000-9000 rpm, and the time of the second homogenization treatment is 2.5-3.5 min; (3) The temperature of the third homogenization treatment is 10-40°C, the rotation speed of the third homogenization treatment is 9500-10500rpm, and the time of the third homogenization treatment is 1-2min.

10. Use of the composition according to claims 1 to 7, or the composition for improving dull skin tone and anti-wrinkle prepared by the preparation method according to claim 8 or 9 in cosmetics.

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