Atomization device, atomization liquid, microcapsule, preparation method of microcapsule and wall material formula

Abstract

The invention provides an atomization device, an atomization liquid, a microcapsule, a preparation method of the microcapsule and a wall material formula, a wall material in the atomization device comprises modified dietary cellulose, pectin, konjac polysaccharide, polyethylene glycol and modified starch, the modified dietary cellulose is adopted as a main component to be compounded with other compositions to serve as a wall material raw material, and the wall material raw material can be dissolved by PG / VG in a proper period, so that the wall material can be dissolved by PG / VG in a proper period; and the core material wrapped by the wall material can be slowly released within a proper period under the influence of temperature and osmotic pressure. The modified dietary fiber has long action time of antibacterial activity, can be used as a natural food preservative, has good oxidation resistance and emulsifying performance, can significantly improve the embedding effect, and makes the microcapsule surface present a uniform and porous microstructure.

Description

Technical Field

[0001] The present application relates to the technical field of microcapsules, and in particular to an atomizing device, an atomizing liquid, a microcapsule, a preparation method thereof, and a wall material formula. Background Art

[0002] During the process of puffing, the atomizer device may encounter problems such as the taste changing or becoming lighter after several puffs, which affects the taste of the puff. In order to improve the quality of the atomizer matrix, reduce the weakening time, appropriately slow down various excessive chemical reactions of the atomizer matrix, and reduce the taste of the atomizer matrix from becoming lighter and lighter, it has become a technical problem that atomizer companies need to solve urgently. Summary of the invention

[0003] The embodiments of the present application provide an atomization device, an atomization liquid, a microcapsule, a preparation method thereof, and a wall material formula, which are used to solve the problem that the taste of the atomization matrix becomes lighter or changes.

[0004] In some embodiments, a microcapsule wall material formula is provided, characterized in that, by weight, the microcapsule wall material formula comprises:

[0005]

[0006]

[0007] In some embodiments, the modified dietary cellulose comprises hydroxypropyl methylcellulose.

[0008] In some embodiments, a method for preparing a microcapsule is provided, comprising:

[0009] Prepare wall material solution;

[0010] adding the core material into the wall material solution and stirring to obtain a premixed solution;

[0011] Adding gelatin to the premixed solution, heating to a first preset temperature, and stirring to form an emulsion;

[0012] The emulsion is dropped into an organic solvent and cooled to a second preset temperature to precipitate a crude product, and the crude product is collected, washed, and dried to obtain target microcapsules.

[0013] In some embodiments, the first preset temperature is 50-70° C.; and / or,

[0014] The second preset temperature is 10-20°C.

[0015] In some embodiments, the wall material solution is prepared by dissolving modified dietary cellulose, pectin, konjac polysaccharide, polyethylene glycol, and modified starch in deionized water to form a dietary cellulose system, and adding calcium chloride solution and glycerol to the dietary cellulose system and stirring to obtain a wall material solution.

[0016] In some embodiments, the mass of the glycerol is 15-20% of the total mass of the wall material solution; and / or,

[0017] The concentration of the calcium chloride solution is 10% and the mass of the calcium chloride solution is 1-2% of the total mass of the wall material solution.

[0018] In some embodiments, the mass ratio of the wall material solution to the core material is 1:(1-1.5); and / or,

[0019] The mass ratio of the gelatin to the wall material solution is 1:(2.5-3.5).

[0020] In some embodiments, a microcapsule is provided, wherein the microcapsule is prepared by the above-mentioned microcapsule preparation method, or the microcapsule comprises a wall material and a core material, and the wall material comprises, by weight:

[0021]

[0022] The wall material is wrapped around the surface of the core material to form a coating layer, and a molecular channel is formed on the coating layer.

[0023] In some embodiments, the atomized liquid includes the above-mentioned microcapsules.

[0024] In some embodiments, an atomization device is provided, wherein the atomization device includes the atomization liquid described above.

[0025] The wall material in this application uses modified dietary cellulose as the main component and is compounded with other compositions as the wall material raw material. It can be dissolved by PG / VG within an appropriate period, and can be affected by temperature and osmotic pressure to make the core material wrapped by the wall material slowly released within an appropriate period. The antibacterial activity of modified dietary cellulose lasts for a long time and can be used as a natural food preservative. The modified dietary cellulose has good antioxidant and emulsifying properties, which can significantly improve the embedding effect and make the surface of the microcapsule present a uniform and porous microstructure. BRIEF DESCRIPTION OF THE DRAWINGS

[0026] In order to more clearly illustrate the technical solutions in the embodiments of the present application, the drawings required for use in the description of the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present application. For ordinary technicians in this field, other drawings can be obtained based on these drawings without creative work.

[0027] Figure 1 is a schematic diagram of the structure of microcapsules in some embodiments of the present application;

[0028] Figure 2 is a schematic flow chart of a method for preparing microcapsules in some embodiments of the present application;

[0029] Figure 3 is a process flow chart of preparing microcapsules in some embodiments of the present application;

[0030] Figure 4 It is a schematic diagram of the overall structure of the atomization device in some embodiments of the present application. DETAILED DESCRIPTION

[0031] The present application is further described in detail below in conjunction with the accompanying drawings and examples. It is particularly noted that the following examples are only used to illustrate the present application, but are not intended to limit the scope of the present application. Similarly, the following examples are only some embodiments of the present application rather than all embodiments, and all other embodiments obtained by ordinary technicians in the field without making creative work are within the scope of protection of the present application.

[0032] The terms "including" and "having" and any variations thereof in the embodiments of the present application are intended to cover non-exclusive inclusions. For example, a process, method, system, product, or device that includes a series of steps or units is not limited to the listed steps or units, but may optionally include steps or units that are not listed, or may optionally include other steps or components that are inherent to these processes, methods, products, or devices.

[0033] Throughout the content of this disclosure, certain embodiments may be disclosed in the form of ranges. However, it should be understood that the description in the form of ranges is only for convenience and brevity and should not be interpreted as a hard limit to the disclosed range. Therefore, the description of the range should be considered to include all possible sub-ranges disclosed specifically and the individual numerical values ​​within the range. For example, the description of a range, such as a range from 1 to 6, should be regarded as having specifically disclosed sub-ranges, such as from 1 to 3, from 1 to 4, from 1 to 5, from 2 to 4, from 2 to 6, from 3 to 6, etc., and the individual numerical values ​​within the range, for example, 1, 2, 3, 4, 5 and 6. This application is independent of the width of the range.

[0034] Certain embodiments may be described broadly and generally herein. Each narrower class and subgeneric grouping falling within the general disclosure also forms part of the present disclosure. This includes a general description of embodiments with proviso or negative limitation (removing any subject matter from the genus), whether or not the removed content is specifically cited herein.

[0035] The experimental methods in the following examples without specifying specific conditions are usually based on conventional conditions. Unless otherwise specified, the percentages and parts are calculated by weight.

[0036] The present application embodiment provides a microcapsule wall material formula. Based on the total mass of the microcapsule wall material formula, the microcapsule wall material comprises, by mass percentage:

[0037]

[0038] Among them, modified dietary cellulose can include modified cellulose such as hydroxypropyl methylcellulose, carboxymethyl cellulose, and nano-microcrystalline cellulose. Cellulose is an extremely abundant natural renewable polymer with good biocompatibility and biodegradability, but the high crystallinity and poor solubility of natural cellulose have largely limited its application in more fields. Compared with natural cellulose, the surface of cellulose derivatives is easy to modify, and the mechanical properties and biocompatibility are better, which broadens the application field of cellulose. Modified dietary cellulose has good emulsifying ability, foaming property, solubility, antioxidant and antibacterial activity, which can significantly improve the embedding effect. Optionally, the present application uses hydroxypropyl methylcellulose as the main component of the wall material. Hydroxypropyl methylcellulose can form a transparent colloidal solution in water, and its rheological properties can be adjusted by adjusting the concentration and pH value, which is conducive to the formation of an artificial semipermeable membrane. The artificial semipermeable membrane formed by hydroxypropyl methylcellulose can be used as a coating layer to encapsulate the core material to form a microcapsule, and the surface of the microcapsule presents a uniform and porous microstructure. The mass fraction of hydroxypropyl methylcellulose is about 20 parts to 45 parts, for example, it can be 20 parts, 24 parts, 25 parts, 26 parts, 27 parts, 28 parts, 29 parts, 30 parts, 31 parts, 32 parts, 33 parts, 34 parts, 35 parts, 38 parts, 40 parts, 42 parts, 45 parts, etc., which are not listed here one by one. In some embodiments, the mass fraction of hydroxypropyl methylcellulose can also be selected from 24 parts to 42 parts.

[0039] Pectin and konjac polysaccharide have good solubility, low viscosity, and are widely available, have many types, and are cheap. In certain embodiments, the mass fraction of pectin can be about 5 parts-10 parts, such as 5 parts, 6 parts, 7 parts, 8 parts, 9 parts, 10 parts, and the content of pectin can also be selected from 6 parts-8.5 parts; The mass fraction of konjac polysaccharide is about 10 parts-20 parts, such as 10 parts, 11 parts, 12 parts, 13 parts, 14 parts, 15 parts, 16 parts, 17 parts, 18 parts, 19 parts, 20 parts, and the mass fraction of konjac polysaccharide can also be selected from 12 parts-19 parts.

[0040] Polyethylene glycol has good film-forming property, stable chemical properties, high mechanical strength, and convenient storage and transportation. Polyethylene glycol can be used as a dispersant to form a thin film on the surface of water-insoluble substances, wrapping the molecules of the substance to prevent them from combining and aggregating. This coating effect can effectively inhibit the precipitation and agglomeration of solid particles and maintain the stability of the dispersed system. The content of polyethylene glycol is 1 part to 9 parts, for example, it can be 1 part, 2 parts, 3 parts, 4 parts, 5 parts, 6 parts, 7 parts, 8 parts, 9 parts, etc.

[0041] The modified starch in the microcapsule wall material formula can specifically be carboxymethyl starch, sodium starch phosphate, octenyl succinate starch ester and various cyclodextrins. The modified starch has the characteristics of safety, high efficiency, biodegradability and strong adsorption compared to natural starch. The modified starch can embed easily oxidized substances or bioactive substances in the internal cavity of the microcapsule spherical aggregates, play the role of anti-oxidation, enhancing physical and chemical stability and improving storage performance. The mass fraction of modified starch is about 0.5-3.5 parts, for example, it can be 0.5 parts, 0.6 parts, 0.7 parts, 0.8 parts, 0.9 parts, 1 parts, 1.1 parts, 1.2 parts, 1.3 parts, 1.4 parts, 1.5 parts, 1.6 parts, 1.7 parts, 1.8 parts, 1.9 parts, 2 parts, 2.5 parts, 3 parts, 3.5 parts. In some embodiments, the mass fraction of modified starch can be selected from 0.8-1.8 parts.

[0042] The microcapsule wall material formula also includes a solvent, and the solvent can be deionized water. In some embodiments, the deionized water in the microcapsule wall material formula is 20 parts to 55 parts, for example, 20 parts, 25 parts, 30 parts, 35 parts, 40 parts, 45 parts, 50 parts, and 55 parts.

[0043] See also Figure 1 , Figure 1 Schematic diagram of the structure of microcapsules in some embodiments of the present application. The present application provides a microcapsule, which includes a wall material and a core material. The wall material is made by using the aforementioned microcapsule wall material formula. The wall material is cross-linked and solidified on the surface of the core material 100 by the cold cutting and dripping method to form a coating layer 200. A molecular channel 300 of 1000 to 10000 nm is formed on the coating layer 200. The wall material can be dissolved by PG (propylene glycol) / VG (glycerol), so that the core material 100 loaded in the microcapsule can be sustained-released within an appropriate period, and has good storage stability and an appropriate sustained-release effect.

[0044] See also Figure 2 , Figure 2 : is a schematic diagram of the process for preparing microcapsules in some embodiments of the present application, and the specific process flow is as follows:

[0045] Step S1, preparing a wall material solution.

[0046] In this embodiment, the wall material solution is prepared by dissolving water-soluble cellulose, pectin, konjac polysaccharide, polyethylene glycol, and modified starch in deionized water to form a dietary cellulose system, and adding calcium chloride solution and glycerol to the dietary cellulose system and stirring. The content of each component of the dietary fiber system is configured according to the above-mentioned microcapsule wall material formula.

[0047] In this embodiment, stirring can be performed during the preparation of the wall material solution to mix air into the wall material solution. Specifically, the mixing of air can be achieved by selecting a specific stirring device, controlling the stirring angle and speed, etc. Of course, stirring can also be performed after the wall material solution is prepared, that is, after the wall material solution is prepared, the wall material solution is stirred to mix air.

[0048] In step S1, the mass of glycerol is 15-20% of the total mass of the wall material solution. For example, the mass of glycerol is about 15%, 16%, 17%, 18%, 19%, 20% of the total mass of the wall material solution. In some embodiments, it can be 16.7%.

[0049] In step S1, the concentration of the calcium chloride solution is 10% and the mass of the calcium chloride solution is 1-2% of the total mass of the wall material solution. For example, the mass of the calcium chloride solution is about 1%, 1.1%, 1.2%, 1.3%, 1.4%, 1.5%, 1.6%, 1.7%, 1.8%, 1.9%, 2% of the total mass of the wall material solution. In some embodiments, it can be 1.33%.

[0050] Step S2: adding the core material into the wall material solution and stirring to obtain a premixed solution.

[0051] In step S2, the mass ratio of the wall material solution to the core material is 1:(1-1.5), for example, the mass ratio of the wall material solution to the core material is 1:1 or 1:1.1 or 1:1.2 or 1:1.3 or 1:1.4 or 1.1.5, and in some embodiments, it can be about 1:1.33. The core material includes a flavor composition, which is at least one of sweeteners, cooling agents, flavors and spices with various flavors, such as menthol, cinnamon oil, vanillin, ethyl vanillin, ethyl maltol, geranium oil, lavender oil, perilla oil, WS-23, neotame, etc. The stirring time after the core material is added to the wall material solution is 30 minutes.

[0052] Step S3, adding gelatin to the premixed solution, heating to a first preset temperature, and stirring to form an emulsion.

[0053] The first preset temperature may be 50-70°C, such as 50°C, 55°C, 60°C, 65°C, 70°C, etc.

[0054] In step S3, the mass ratio of gelatin to the wall material solution is 1:2.5-3.5. For example, the mass ratio of gelatin to the wall material solution can be about 1:2.5 or 1:3 or 1:3.5. Gelatin, as a protein with zwitterionic electrolyte properties, exhibits abundant positive charges under specific pH conditions, while the premixed solution exhibits negative charges. When the two are mixed, due to the interaction between the charges, they will neutralize and form a complex precipitate, thereby forming a coating layer of the microcapsule. After the wall material solution is mixed with the core material, gelatin is added, heated to 50-70°C in a water bath, and stirred for 30 minutes, which can further drive the modified dietary cellulose to cross-link on the surface of the core material and improve the encapsulation rate.

[0055] Step S4, dropping the emulsion into an organic solvent, and cooling the mixture to a second preset temperature to precipitate a crude product, and collecting, washing, and drying the crude product to obtain target microcapsules.

[0056] The second preset temperature may be 10-20°C, such as 10°C, 12°C, 15°C, 18°C, 20°C, etc.

[0057] In step S4, a cold water bath can be used for cooling, and the droplets added can be solidified by cold cutting and dripping at different cooling rates, so that the emulsion and the organic solvent are mixed to form a two-phase mixed liquid. The organic solvent can be a non-polar organic solvent such as hexane. Hexane is insoluble in water and has strong hydrophobicity. The water in the core material and the wall material gathers inward, so that the wall material is cross-linked and solidified on the surface of the core material and forms a molecular channel with a diameter of 1000 to 10000 nm. Finally, the oil phase is separated to obtain a crude product, which is then rinsed with 75% ethanol, dried at 30°C, and then placed in a brown bottle and sealed to avoid light.

[0058] See also Figure 3 , Figure 3 This is a process flow chart of preparing microcapsules in some embodiments of the present application. Some embodiments of the present application use different microcapsule wall material formulas to prepare six types of microcapsules. The specific process and the proportion of each component are as follows:

[0059] Embodiment 1:

[0060] 1g of hydroxypropyl methylcellulose, 1g of pectin, 5g of konjac polysaccharide, 0.1g of polyethylene glycol, and 0.01g of modified cassava starch are added to 54.39g of deionized water for dissolution, and then 1g of 10% calcium chloride solution and 12.5g of glycerol are added to the deionized water and stirred to obtain 75g of wall material solution; 100g of flavor is added to the wall material solution, and stirred for 30min to obtain a premixed solution; 25g of gelatin is added to the premixed solution for emulsification, heated to 60°C in a water bath, and stirred for 30min to obtain an emulsion; the emulsion is slowly dripped into 500g of hexane using a dropping device, and the mixture is cooled to 20°C to form a two-phase mixed solution, and then a crude product is obtained by oil phase separation; the crude product is washed with a 75% ethanol solution, filtered, and dried at 30°C to obtain a finished microcapsule.

[0061] Embodiment 2:

[0062] 5g of hydroxypropyl methylcellulose, 2g of pectin, 6g of konjac polysaccharide, 0.25g of polyethylene glycol, and 0.05g of 1% glycerol are slowly added to 48.2g of deionized water for dissolution, and then 1g of 10% calcium chloride solution and 12.5g of glycerol are added to the deionized water and stirred to obtain 75g of wall material solution; 100g of flavor is added to the wall material solution, and stirred for 30min to obtain a premixed solution; 25g of gelatin is added to the premixed solution for emulsification, heated to 60°C in a water bath, and stirred for 30min to obtain an emulsion; the emulsion is slowly dripped into 500g of hexane using a dropping device, and the mixture is cooled to 20°C to form a two-phase mixed solution, and then a crude product is obtained by oil phase separation; the crude product is washed with a 75% ethanol solution, filtered, and dried at 30°C to obtain a finished microcapsule.

[0063] Embodiment three:

[0064] 10g of hydroxypropyl methylcellulose, 3g of pectin, 7g of konjac polysaccharide, 0.5g of polyethylene glycol, and 0.1g of 10% glycerol are slowly added to 40.9g of deionized water for dissolution, and then 1g of 10% calcium chloride solution and 12.5g of glycerol are added to the deionized water and stirred to obtain 75g of wall material solution; 100g of flavor is added to the wall material solution, and stirred for 30min to obtain a premixed solution; 25g of gelatin is added to the premixed solution for emulsification, heated to 60°C in a water bath, and stirred for 30min to obtain an emulsion; the emulsion is slowly dripped into 500g of hexane using a dropping device, and the mixture is cooled to 20°C to form a two-phase mixed solution, and then a crude product is obtained by oil phase separation; the crude product is washed with a 75% ethanol solution, filtered, and dried at 30°C to obtain a finished microcapsule.

[0065] Embodiment 4:

[0066] 15g of hydroxypropyl methylcellulose, 4g of pectin, 8g of konjac polysaccharide, 1g of polyethylene glycol, and 0.5g are slowly added to 33g of deionized water to dissolve, and then 1g of 10% calcium chloride solution and 12.5g of glycerol are added to the deionized water and stirred to obtain 75g of wall material solution; 100g of flavor is added to the wall material solution, and stirred for 30 minutes to obtain a premixed solution; 25g of gelatin is added to the premixed solution for emulsification, heated to 60°C in a water bath, and stirred for 30 minutes to obtain an emulsion; the emulsion is slowly dripped into 500g of hexane using a dropping device, and the mixture is cooled to 20°C to form a two-phase mixed solution, and then a crude product is obtained by oil phase separation; the crude product is washed with a 75% ethanol solution, filtered, and dried at 30°C to obtain a finished microcapsule.

[0067] Embodiment five:

[0068] Take 20g of hydroxypropyl methylcellulose, 5g of pectin, 9g of konjac polysaccharide, 2.5g of polyethylene glycol, and 1g and slowly add them into 24g of deionized water to dissolve, then add 1g of 10% calcium chloride solution and 12.5g of glycerol into the deionized water and stir to obtain 75g of wall material solution; add 100g of flavor into the wall material solution and stir for 30min to obtain a premixed solution; add 25g of gelatin to the premixed solution for emulsification, heat it to 60℃ in a water bath, and stir for 30min to obtain an emulsion; use a dropping device to slowly drop the emulsion into 500g of hexane, cool it to 20℃ to form a two-phase mixed solution, and then separate it into an oil phase to obtain a crude product; wash the crude product with a 75% ethanol solution, filter it, and dry it at 30℃ to obtain a finished microcapsule.

[0069] Embodiment six:

[0070] Take 25g of hydroxypropyl methylcellulose, 6g of pectin, 10g of konjac polysaccharide, 5g of polyethylene glycol, and 2g and slowly add them into 13.5g of deionized water to dissolve, then add 1g of 10% calcium chloride solution and 12.5g of glycerol into the deionized water and stir to mix to obtain 75g of wall material solution; add 100g of flavor into the wall material solution and stir for 30min to obtain a premixed solution; add 25g of gelatin to the premixed solution for emulsification, heat it to 60℃ in a water bath, stir for 30min to obtain an emulsion; use a dropping device to slowly drop the emulsion into 500g of hexane, cool it to 20℃ to form a two-phase mixed solution, and then separate it into an oil phase to obtain a crude product; wash the crude product with a 75% ethanol solution, filter it, and dry it at 30℃ to obtain a finished microcapsule.

[0071] The microcapsules obtained from the above six experiments were numbered A1 to A6 and quality checked:

[0072] (1) Place each group of microcapsules at room temperature for 1 h, 3 h, 6 h, 12 h, and 24 h, and observe whether there is leakage.

[0073] (2) Gently press the microcapsule to see if it is deformed or broken.

[0074] (3) Check whether the particle size is qualified: The mass of microcapsules with a particle size of less than 0.5 mm obtained by screening with a 35-mesh sieve is q1, and the total mass of the prepared microcapsules is q2. If q1 / q2>80%, the particle size is qualified, otherwise it is unqualified.

[0075] (4) The supernatant in each group of hexane solutions was taken to measure the concentration of the flavor, and the amount of residual flavor in the solution was calculated as m1. The original amount of flavor added when preparing the microcapsules was m2. The embedding rate of the microcapsules was calculated according to the following formula:

[0076] Embedding rate = (m2-m1) / m2×100%

[0077] The quality inspection results are as follows:

[0078] Quality Check A1 A2 A3 A4 A5 A6 Is there leakage? yes yes yes no no no Is it fragile? yes yes yes no no no Whether it is deformed no no no no no yes Is the particle size qualified? no no yes yes yes yes Embedding rate (%) 61.8 62.6 64.5 65.4 70.3 67.7

[0079] The experimental results show that the microcapsule embedding rate prepared by embodiment 5 is the highest, and the microcapsule embedding rates obtained by the above embodiment 4, embodiment 5 and embodiment 6 are all above 65%, and are not easy to leak and not easy to break. While the components of embodiment 1, embodiment 2 and embodiment 3 are the same, the proportions are different, and the resulting product embedding rate is low, and there are problems of easy leakage and fragility. The present application embodiment has also been tested by similar experiments for many times, and it is found that when the content of hydroxypropyl methylcellulose exceeds 45%, as the addition amount of hydroxypropyl methylcellulose increases, the obtained microcapsule is more easily deformed, and the embedding rate of the microcapsule is reduced to below 65%. When the hydroxypropyl methylcellulose content in the microcapsule wall material is 20-45%, the pectin content is pectin 5-10%, the konjac polysaccharide content is 10-20%, the polyethylene glycol content is 1-9%, and the modified starch content is 0.5-3.5%, the obtained microcapsule quality test results are good.

[0080] In some embodiments, the present application provides an atomized liquid, which includes propylene glycol, glycerin and the above-mentioned microcapsules, wherein the mass of the microcapsules is approximately 10% of the total mass of the atomized liquid.

[0081] See also Figure 4 , Figure 4 Schematic diagram of the overall structure of the atomizing device in some embodiments of the present application. In some embodiments, the present application further provides an atomizing device, the atomizing device comprising an atomizer 400, the atomizer 400 having an inner cavity, the inner cavity being injected with the above-mentioned atomizing liquid.

[0082] In some embodiments, the atomizing device may further include an atomizing host 500, which is used to heat the atomizing liquid in the atomizer 400 and generate an aerosol. The atomizing host 500 and the atomizer 400 may be a disposable atomizing device formed by a fixed connection or a replaceable atomizing device formed by a detachable connection.

[0083] It is understandable that during the use of the atomizer, the microcapsule part of the atomized liquid will sink to the bottom, the coating layer of the microcapsule can be dissolved by PG / VG within an appropriate period, and during the suction process, external conditions such as temperature changes and osmotic pressure changes will also affect the rupture of the microcapsules. By properly utilizing these favorable conditions, the microcapsules can play a role of supplementary sustained release during the suction process, thereby achieving the purpose of continuous aroma enhancement.

[0084] The following is to explore the amount of microcapsules added and verify the sustained release effect of microcapsules in the atomized liquid:

[0085] (1) Dissolution test without temperature and pressure changes:

[0086] The effect of microcapsule flavor is mainly in the middle and late stages of the atomized matrix. If it is released completely or delayed too early, it will not work. The core material in the above-mentioned Examples 1 to 6 is a colored (yellow) flavor as the core material. The microcapsules prepared in the experiments of Examples 4, 5 and 6 are made into three groups of atomized liquids according to the ratio of microcapsules: PG: VG = 3:3:4. The three groups of atomized liquids are sealed and placed at room temperature. It is recorded and observed whether the atomized liquid changes in color without temperature and pressure changes.

[0087] After observation and recording, the three groups of atomized liquids had no color change in the first three weeks, turned slightly yellow in the fourth week, and gradually deepened in the following weeks. After the tenth week, the number of microcapsules was observed to decrease. It can be seen that without temperature and pressure changes, the microcapsules can gradually dissolve and rupture within ten weeks to release the essence encapsulated therein, that is, the microcapsules prepared according to the microcapsule wall material formula and method of the present application have a better sustained release effect in PG&VG solution.

[0088] (2) Addition amount test:

[0089] During normal puffing, the dissolution rate of the microcapsules will change with the change of the puffing pressure. Different amounts of microcapsules added will bring different taste changes under different puffing pressures. In order to find the appropriate amount of addition, 0%, 1%, 5%, 10%, and 15% of microcapsules are added to the atomization matrix solvent (PG&VG solvent) to form five groups of atomization liquids, which are marked as B1 to B5 respectively, and the five groups of atomization liquids are loaded into the atomization device. First, 40% of the total number of puffs of the atomization device is puffed, and then 10% of the total number of puffs is puffed each time. 100 volunteers who meet the sensory evaluation standards are recruited to conduct sensory evaluation on the five groups of atomization liquids, and the comprehensive scores of comfort, irritation, and durability are comprehensively scored, with 10 points being the highest. The 100 people are divided into 5 groups, and the average score of each group is recorded, and the average score of each group of volunteers is taken as the final result of the experiment.

[0090] The scoring criteria for the sensory evaluation experiment are as follows:

[0091]

[0092]

[0093] According to the above-mentioned scoring criteria, a comparison experiment of addition amounts was conducted, and the sensory evaluation results were shown in the following table.

[0094] project B1 B2 B3 B4 B5 Comfort 6.2 6.8 8 8.5 3.5 Irritant 9.8 9.5 8.5 8 5.7 Durability 2 2.5 5.6 7.4 8.8

[0095] The above results show that an addition amount of 10% is ideal. It has the effect of slow-release flavors during taste changes, can greatly reduce the impact of taste fading and taste change, and has no obvious irritation and a high degree of comfort.

[0096] The above descriptions are only some embodiments of the present application, and do not limit the protection scope of the present application. Any equivalent device or equivalent process transformation made using the contents of the present application specification and drawings, or directly or indirectly used in other related technical fields, are also included in the patent protection scope of the present application.

Claims

1. A microcapsule wall material formula, characterized in that: The microcapsule wall material formula includes, by weight:

2. The microcapsule wall material formulation according to claim 1, characterized in that: The modified dietary cellulose includes hydroxypropyl methylcellulose.

3. A method for preparing microcapsules, characterized in that: include: Prepare wall material solution; adding the core material into the wall material solution and stirring to obtain a premixed solution; Adding gelatin to the premixed solution, heating to a first preset temperature, and stirring to form an emulsion; The emulsion is dropped into an organic solvent and cooled to a second preset temperature to precipitate a crude product, and the crude product is collected, washed, and dried to obtain target microcapsules.

4. The method for preparing microcapsules according to claim 3, characterized in that: The first preset temperature is 50-70° C.; and / or, The second preset temperature is 10-20°C.

5. The method for preparing microcapsules according to claim 3, characterized in that: The preparation method of the wall material solution is as follows: modified dietary cellulose, pectin, konjac polysaccharide, polyethylene glycol and modified starch are dissolved in deionized water to form a dietary cellulose system, and calcium chloride solution and glycerol are added to the dietary cellulose system and stirred to obtain the wall material solution.

6. The method for preparing microcapsules according to claim 5, characterized in that: The mass of the glycerol is 15-20% of the total mass of the wall material solution; and / or, The concentration of the calcium chloride solution is 10% and the mass of the calcium chloride solution is 1-2% of the total mass of the wall material solution.

7. The method for preparing microcapsules according to claim 3, characterized in that: The mass ratio of the wall material solution to the core material is 1:(1-1.5); and / or, The mass ratio of the gelatin to the wall material solution is 1:(2.5-3.5).

8. A microcapsule, characterized in that The microcapsule is prepared by the method for preparing a microcapsule according to any one of claims 3 to 7, or the microcapsule comprises a wall material and a core material, and the wall material comprises, by weight: The wall material is wrapped around the surface of the core material to form a coating layer, and a molecular channel is formed on the coating layer.

9. An atomized liquid, characterized in that: The atomized liquid includes the microcapsules as claimed in claim 8.

10. An atomizing device, characterized in that: The atomizing device comprises the atomizing liquid as claimed in claim 9.

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