Dynamically sealed rotary constant-pressure filling device

By designing a dynamically sealed rotary constant pressure filling device, using the cone sealing technology of line contact and the spring adjustment structure, the non-sealing and pressurized filling of the liquid storage tank of the rotary filling machine in the prior art is solved. The problems of online cleaning and online sterilization achieve high-precision constant pressure filling and low-waste liquid treatment.

CN119390002APending Publication Date: 2025-02-07CHANGSHA ZHONGYI PHARMA MACHINERY
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Patent Information

Application Number
CN202411747667.8
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-12-02
Publication Date
2025-02-07

AI Technical Summary

Technical Problem

The existing rotary filling machine cannot be sealed and pressurized in the liquid storage tank, and cannot be dynamically cleaned and sterilized, resulting in inaccurate loading errors, serious waste of medicine and low cleaning and sterilization efficiency.

Method used

A dynamically sealed rotary constant pressure filling device is designed, by providing a detachable first friction seat at the bottom of the constant pressure tank and a rotating second friction seat on the filling mechanism, between the two The first conical surface and the second conical surface are in line contact, and cooperate with the positioning rod and the spring to achieve a dynamic seal, and reduce the friction force of the conical surface by adjusting the pressure of the spring.

Benefits of technology

Constant pressure filling is realized, the filling accuracy is improved (≤±0.5%), the waste of medicine is reduced, the liquid filling is ensured that the liquid filling meets the GMP requirements, and dynamic online cleaning and online sterilization are realized.

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Abstract

The invention discloses a dynamically sealed rotary constant-pressure filling device which comprises a constant-pressure tank, a first friction seat is detachably connected to the bottom of the constant-pressure tank, a filling mechanism capable of rotating is arranged below the first friction seat, and a second friction seat extending into the first friction seat is arranged on the filling mechanism. The first friction seat and the second friction seat are respectively provided with a first conical surface and a second conical surface, the second conical surface is in linear contact with the first conical surface, the distance between the first conical surface and the second conical surface is gradually increased downwards from the connecting position, a plurality of positioning rods are arranged on the constant-pressure tank in a sliding manner, and a spring is arranged on the constant-pressure tank; the spring is used for applying downward pressure to the first conical surface, a liquid outlet of the constant-pressure tank is communicated with the second friction seat through the first friction seat, and the hardness of the first friction seat is smaller than that of the second friction seat. Compared with the prior art, the problem that a liquid storage tank of an existing filling machine cannot conduct constant-pressure filling is solved, the productivity and the filling quantity precision of the rotary filling machine are improved, and no residual tail liquid is left.
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Description

Technical Field

[0001] The invention relates to the technical field of constant pressure filling, in particular to a dynamic sealing rotary constant pressure filling device. Background Art

[0002] Filling machines are key quality control points in the production process of liquid preparations in the pharmaceutical industry. The structure and capacity of the filling machine, accurate metering, and easy cleaning and disinfection are the technical issues that need to be focused on in the production of liquid preparations in the pharmaceutical industry. The existing rotary filling machine generally adopts gravity self-flow filling. Figure 1 This method ensures the filling and metering of the liquid medicine by controlling the self-flow timing of the liquid medicine; the liquid storage tank is operated in a non-closed manner (the liquid inlet pipe is stationary and does not rotate and is separated from the liquid storage tank by a distance of 5 to 10 mm, and the liquid storage tank rotates with the main body turntable of the machine). The impact of the liquid inlet will cause large fluctuations in the liquid level, and the self-weight pressure value of the liquid medicine in the tank will also change greatly, resulting in inaccurate control of the filling error. In particular, there will be a large amount of filling tail liquid at the end, and the waste of liquid medicine is quite serious. In addition, the liquid storage tank and the filling pipeline can only be cleaned and sterilized online statically. If a rotary joint is used for filling, the friction generated by the rotary joint after a long period of friction will affect the quality of the liquid medicine; secondly, the rotary joint has many parts, which will also affect the quality of the liquid medicine, and it is also not easy to clean and sterilize. Summary of the invention

[0003] The invention provides a dynamically sealed rotary constant pressure filling device, which is used to solve the problems that the liquid storage tank of the existing rotary filling machine cannot be sealed for pressurized filling and cannot be dynamically cleaned and sterilized online.

[0004] The present invention provides a dynamically sealed rotary constant-pressure filling device, comprising a constant-pressure tank, wherein a first friction seat is detachably connected to the bottom of the constant-pressure tank, a rotatable filling mechanism is provided below the first friction seat, a second friction seat extending into the first friction seat is provided on the filling mechanism, the first friction seat and the second friction seat are respectively provided with a first conical surface and a second conical surface, the second conical surface is in line contact with the first conical surface, the distance between the first conical surface and the second conical surface gradually increases from the connection position downward, a plurality of positioning rods are slidably arranged on the constant-pressure tank, a spring is provided on the constant-pressure tank, the spring is used to apply downward pressure to the first conical surface, the liquid outlet of the constant-pressure tank is connected with the second friction seat through the first friction seat, and the hardness of the first friction seat is less than that of the second friction seat.

[0005] Preferably, a support plate is fixed on the constant pressure tank, the positioning rod is slidably connected to the support plate, the spring is located on the positioning rod above the support plate, and the positioning rod is threadedly connected with an adjusting nut above the spring.

[0006] Preferably, the positioning rod is threadedly connected to a limiting nut below the support plate.

[0007] Preferably, a pressing sleeve is provided on the outer side of the first friction seat, a pressing plate is provided on the lower end of the pressing sleeve, and the pressing sleeve is fixed to the constant pressure tank via bolts above the first friction seat and the pressing plate.

[0008] Preferably, a first sealing ring is provided between the first friction seat and the constant pressure tank.

[0009] Preferably, a third conical surface is provided on the inner side of the first friction seat above the first conical surface, and the inclination direction of the third conical surface is opposite to the inclination direction of the first conical surface.

[0010] Preferably, the second friction seat is fixed to the filling mechanism by bolts.

[0011] Preferably, a fourth conical surface is provided at the inner upper end of the second friction seat, and the inclination direction of the fourth conical surface is opposite to the inclination direction of the second conical surface.

[0012] Preferably, the first friction seat is made of polyetheretherketone, and the second friction seat is made of stainless steel.

[0013] Preferably, the cone angle of the first friction seat is 40°, and the cone angle of the second friction seat is 38°.

[0014] Compared with the prior art, in the present invention, the first conical surface and the second conical surface are designed to be in line contact, and the distance between the first conical surface and the second conical surface gradually increases downward from the connection position thereof. In combination with the positioning rod and the spring, and the structural design that the hardness of the first friction seat is less than the hardness of the second friction seat, the first conical surface and the second conical surface are dynamically sealed when the constant pressure tank is under pressure, and the problem that the liquid storage tank of the existing rotary filling machine cannot be filled at constant pressure is solved. The design improves the production capacity and filling accuracy of the rotary filling machine (filling accuracy: ≤±0.5%), and does not leave residual tail liquid, reducing the waste of liquid medicine. After long-term use, the first conical surface and the second conical surface can still maintain a state of line contact and maintain good sealing performance. The debris generated by the friction of the conical surface will be discharged downward from the gap between the first conical surface and the second conical surface, ensuring that the filling of the liquid medicine meets the GMP requirements. Secondly, the overall structure is simple, and only the first friction seat and the second friction seat are in contact with the liquid, and the upper end of the conical surface can always be kept in sealed contact during use, leaving no dead corners for cleaning and sterilization. Fourthly, the first friction seat with a detachable structure design is convenient for later maintenance. Fifth, by adjusting the pressure of the spring, the friction of the cone surface can be reduced as much as possible under the premise of good sealing, so as to extend the service life of the friction seat. Sixth, line contact reduces the friction area and friction resistance. Seventh, dynamic online cleaning and online sterilization are realized. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] In order to more clearly illustrate the technical solutions in the present invention or the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0016] Figure 1 It is a structural schematic diagram of the prior art;

[0017] Figure 2 It is a structural schematic diagram of the present invention;

[0018] Figure 3 It is a cross-sectional schematic diagram of the present invention;

[0019] Figure 4 for Figure 3 A magnified schematic diagram of the structure in the middle.

[0020] Reference numerals:

[0021] 1. Constant pressure tank, 2. First friction seat, 3. Filling mechanism, 4. Second friction seat, 5. Positioning rod, 6. Spring, 7. Support plate, 8. Adjusting nut, 9. Limiting nut, 10. Pressing sleeve, 11. First sealing ring, 12. Telescopic tube, 13. Frame, 14. Liquid storage tank, 15. Liquid inlet pipe, 16. Turntable, 011. Liquid outlet, 021. First cone surface, 022. Third cone surface, 041. Second cone surface, 042. Fourth cone surface, 0101. Pressing plate. DETAILED DESCRIPTION

[0022] In order to make the purpose, technical solution and advantages of the present invention clearer, the technical solution of the present invention will be clearly and completely described below in conjunction with the drawings of the present invention. Obviously, the described embodiments are part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0023] See attached Figure 3 and attached Figure 4The present embodiment provides a dynamically sealed rotary constant pressure filling device, comprising a constant pressure tank 1, a first friction seat 2 being detachably connected to the bottom of the constant pressure tank 1, a rotatable filling mechanism 3 being arranged below the first friction seat 2, a second friction seat 4 extending into the first friction seat 2 being arranged on the filling mechanism 3, the first friction seat 2 and the second friction seat 4 being respectively provided with a first conical surface 021 and a second conical surface 041, the second conical surface 041 being in line contact with the first conical surface 021, which can effectively reduce the friction area and friction resistance, the first conical surface 021 and the second conical surface 041 are in line contact with the first conical surface 021, The distance between the surfaces 041 gradually increases downward from the connection position. A plurality of positioning rods 5 are slidably arranged on the constant pressure tank 1. The constant pressure tank 1 can only float up and down along the positioning rods 5 to ensure that when the second friction seat 4 rotates, the first friction seat 2 and the second friction seat 4 always maintain a coaxial arrangement; a spring 6 is arranged on the constant pressure tank 1, and the spring 6 is used to apply downward pressure to the first conical surface 021 to ensure that the first conical surface 021 and the second conical surface 041 can be effectively sealed and the friction force of the conical surface can be reduced as much as possible, so as to extend the service life of the first friction seat 2 and the second friction seat 4. Specifically, the pressure of the conical surface seal comes from the sum of the dead weight of the constant pressure tank 1 and the internal liquid medicine and the pressure of the spring 6, ensuring that the first conical surface 021 and the second conical surface 041 can be effectively sealed even when there is pressure in the constant pressure tank 1. The liquid outlet 011 of the constant pressure tank 1 is connected to the second friction seat 4 through the first friction seat 2. The hardness of the first friction seat 2 is less than that of the second friction seat 4. The first cone surface 021 is worn first during friction. This setting ensures that the first cone surface 021 and the second cone surface 041 remain in a linear contact state after long-term friction. In the present invention, the constant pressure tank 1 and the first friction seat 2 are stationary, and the filling mechanism 3 drives the second friction seat 4 to rotate in the first friction seat 2. This structural design makes it unnecessary to separate the constant pressure tank 1 and the liquid inlet pipe 15, and constant pressure filling can be achieved. In the present invention, by designing the first conical surface 021 and the second conical surface 041 to be in line contact, the distance between the first conical surface 021 and the second conical surface 041 gradually increases downward from the connection position thereof, and in combination with the positioning rod 5 and the spring 6, and the structural design that the hardness of the first friction seat 2 is less than the hardness of the second friction seat 4, the first conical surface 021 and the second conical surface 041 are dynamically sealed when the constant pressure tank 1 is under pressure, and the problem that the liquid storage tank 14 of the existing rotary filling machine cannot be pressurized for filling is solved. The design improves the production capacity and filling accuracy (filling accuracy: ≤±0.5%) of the rotary filling machine, and does not leave residual tail liquid, thereby reducing the waste of liquid medicine. After long-term use, the first conical surface 021 and the second conical surface 041 can still maintain a state of line contact and maintain good sealing, and the debris generated by the friction of the conical surfaces will be discharged downward from the gap between the first conical surface 021 and the second conical surface 041, ensuring that the filling of liquid medicine meets the GMP requirements. Secondly, the overall structure is simple, and only the first friction seat 2 and the second friction seat 4 are in contact with the liquid. In addition, the upper end of the cone surface can always maintain sealed contact during use, leaving no dead corners for cleaning and sterilization.Fourthly, the first friction seat 2 with a detachable structure design is convenient for later maintenance.

[0024] As another embodiment of the present invention: Figure 2 A support plate 7 is fixed on the constant pressure tank 1, a positioning rod 5 is slidably connected to the support plate 7, a spring 6 is located on the positioning rod 5 above the support plate 7, the positioning rod 5 is threadedly connected with an adjusting nut 8 above the spring 6, and the positioning rod 5 is fixed on the frame 13. The pressure of the spring 6 can be adjusted appropriately by adjusting the nut 8 to ensure that it can be sealed well without leakage and the friction of the cone surface can be reduced as much as possible to extend the service life of the friction seat.

[0025] Specifically, there are two adjusting nuts 8 on the positioning rod 5 .

[0026] As another embodiment of the present invention: the positioning rod 5 is threadedly connected with a limiting nut 9 below the support plate 7, and the limiting nut 9 is used to limit the support plate 7 to prevent the first friction seat 2 from excessively moving downward during operation.

[0027] As another embodiment of the present invention, a telescopic tube 12 is provided between the adjusting nut 8 and the supporting plate 7 , and the spring 6 is located in the telescopic tube 12 .

[0028] An embodiment of the detachable connection between the first friction seat 2 and the constant pressure tank 1: a pressing sleeve 10 is provided on the outside of the first friction seat 2, a pressing plate 0101 is provided at the lower end of the pressing sleeve 10, the first friction seat 2 is located above the pressing plate 0101, the pressing sleeve 10 is fixed to the constant pressure tank 1 by bolts, and the first friction seat 2 is fixed between the pressing sleeve 10 and the constant pressure tank 1 by pressing. Unscrew the bolts, remove the pressing sleeve 10, and then take the first friction seat 2 out of the pressing sleeve 10. This structural design facilitates the replacement of the first friction seat 2.

[0029] As another embodiment of the present invention: a first sealing ring 11 is provided between the first friction seat 2 and the constant pressure tank 1 , and the structural design is used to ensure the sealing performance between the first friction seat 2 and the constant pressure tank 1 .

[0030] As another embodiment of the present invention: a third conical surface 022 is provided on the inner side of the first friction seat 2 above the first conical surface 021, and the inclination direction of the third conical surface 022 is opposite to the inclination direction of the first conical surface 021. This structural design can effectively reduce dead corners for cleaning and sterilization.

[0031] As another embodiment of the present invention: the second friction seat 4 is fixed to the filling mechanism 3 by bolts. This structural design facilitates the later replacement of the second friction seat 4.

[0032] As another embodiment of the present invention: a second sealing ring is provided between the second friction seat 4 and the filling mechanism 3 , and the structural design is used to ensure the sealing performance between the second friction seat 4 and the filling mechanism 3 .

[0033] As another embodiment of the present invention: a fourth conical surface 042 is provided at the inner upper end of the second friction seat 4, and the inclination direction of the fourth conical surface 042 is opposite to the inclination direction of the second conical surface 041. This structural design can effectively reduce the dead angles of cleaning and sterilization.

[0034] As another embodiment of the present invention: the material of the first friction seat 2 is polyetheretherketone, and the material of the second friction seat 4 is stainless steel. This structural design ensures that it can meet three requirements: first, it meets the quality requirements of liquid medicine filling, second, it meets the wear resistance, and third, it meets the first cone surface 021 that can wear before the second cone surface 041.

[0035] As another embodiment of the present invention: the cone angle of the first friction seat 2 is 40°, and the cone angle of the second friction seat 4 is 38°.

[0036] As another embodiment of the present invention: a slot matched with the pressing plate 0101 is provided at the lower end of the first friction seat 2 , and the bottom of the first friction seat 2 is flush with the bottom of the pressing plate 0101 .

[0037] In the present invention, the constant pressure tank 1 does not rotate, which facilitates the air intake pressurization in the tank to become a constant pressure, which is beneficial to improving the capacity of the filling machine. The second stainless steel friction seat 4 below performs a rotating circular motion, and the friction sealing surface is in contact with the upper end line of the cone surface, which reduces the friction area and friction resistance. The manipulator clamps the bottles on the bottle feed dial wheel in turn, and enters the corresponding filling station in turn to perform constant pressure metering filling. The pressure in the constant pressure tank 1 is kept relatively constant through program control, and the liquid medicine is filled into the bottle after the diaphragm valve is opened.

[0038] Constant pressure tank 1 constant pressure control principle: high-precision liquid level detector, pneumatic diaphragm proportional valve (PID control) for liquid inlet, pneumatic proportional valve (PID control) for clean compressed air inlet, pressure sensor with accurate pressure feedback, spray ball for cleaning, various pneumatic diaphragm valves, safety valves and other components are connected to the corresponding interfaces through sanitary fast cards. After the liquid (water, steam), electricity and gas media are connected, the liquid surface pressure reduces the impact fluctuation of liquid inlet through the pre-setting of parameters (liquid level, pressure, temperature) and the joint feedback of electric and gas components. Ensure The comprehensive pressure value of the liquid at the bottom of the tank body (the sum of the deadweight pressure of the liquid in the tank and the clean compressed air pressure above the liquid in the tank) is constant, thereby ensuring that the pressure value of the liquid flowing in the filling pipe connected to the filling head is stable. It is only necessary to accurately adjust the liquid filling time of each filling head on the operation screen to control the precise filling measurement of each filling head. Cleaning and sterilization and other parameter settings and simple operations can be performed on the operation screen to carry out the cleaning and sterilization processes. It is easy to control and adjust, and is applicable to both large-capacity and small-capacity liquid filling machines, with stable and reliable performance.

[0039] Since the comprehensive pressure value of the liquid at the bottom of the tank is controlled to be constant, when the liquid level drops in the final stage of filling, the air supply of the air intake proportional valve (PID control) above the liquid surface is increased, thereby ensuring that all the liquid medicine in the tank is filled, without any residual tail liquid, reducing the waste of liquid medicine.

[0040] The present invention achieves the following beneficial effects:

[0041] (1) The dynamic and static coordination of the constant pressure filling device of the present invention adopts 38° and 40° cone sealing technology, which always maintains the sealing contact of the upper end of the matching cone surface, leaving no dead angle for cleaning and sterilization, and the lower end of the matching cone surface is a clearance fit, which is convenient for friction removal of the matching cone surface.

[0042] (2) The pressure of the conical surface seal comes from the sum of the weight of the constant pressure tank 1 and the internal liquid medicine and the pressure of the spring 6 on the three positioning columns. The pressure of the spring 6 can be adjusted by adjusting the nut 8 to ensure that it can be sealed well without leakage and the friction of the conical surface can be reduced as much as possible to extend the service life of the friction seat.

[0043] (3) The constant pressure tank 1 of the present invention is fixed and does not rotate, which is convenient for the air intake and constant pressure in the tank, improves the filling machine's production capacity and filling accuracy (filling accuracy: ≤±0.5%), and does not leave residual tail liquid, reducing the waste of liquid medicine. The second friction seat 4 below rotates in a circular motion, and the friction sealing surface is in line contact with the upper end of the cone surface, which reduces the friction area and friction resistance.

[0044] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit it. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the aforementioned embodiments, or make equivalent replacements for some of the technical features therein. However, these modifications or replacements do not deviate the essence of the corresponding technical solutions from the spirit and scope of the technical solutions of the embodiments of the present invention.

Claims

1. A dynamic sealing rotary constant pressure filling device, characterized in that: It includes a constant pressure tank, the bottom of which is detachably connected to a first friction seat, a rotatable filling mechanism is provided below the first friction seat, the filling mechanism is provided with a second friction seat extending into the first friction seat, the first friction seat and the second friction seat are respectively provided with a first conical surface and a second conical surface, the second conical surface is in line contact with the first conical surface, the distance between the first conical surface and the second conical surface gradually increases from the connection position downward, a plurality of positioning rods are slidably arranged on the constant pressure tank, a spring is provided on the constant pressure tank, the spring is used to apply downward pressure to the first conical surface, the liquid outlet of the constant pressure tank is connected with the second friction seat through the first friction seat, and the hardness of the first friction seat is less than that of the second friction seat.

2. The dynamic sealing rotary constant pressure filling device according to claim 1 is characterized in that: A support plate is fixed on the constant pressure tank, the positioning rod is slidably connected to the support plate, the spring is located on the positioning rod above the support plate, and the positioning rod is threadedly connected with an adjusting nut above the spring.

3. The dynamic sealing rotary constant pressure filling device according to claim 2 is characterized in that: The positioning rod is threadedly connected with a limiting nut below the supporting plate.

4. The dynamic sealing rotary constant pressure filling device according to claim 1, characterized in that: A pressing sleeve is provided on the outer side of the first friction seat, a pressing plate is provided on the lower end of the pressing sleeve, and the pressing sleeve is fixed to the constant pressure tank via bolts above the first friction seat and the pressing plate.

5. The dynamic sealing rotary constant pressure filling device according to claim 4 is characterized in that: A first sealing ring is provided between the first friction seat and the constant pressure tank.

6. The dynamic sealing rotary constant pressure filling device according to claim 5, characterized in that: A third conical surface is provided on the inner side of the first friction seat above the first conical surface, and the inclination direction of the third conical surface is opposite to the inclination direction of the first conical surface.

7. The dynamic sealing rotary constant pressure filling device according to claim 1, characterized in that: The second friction seat is fixed on the filling mechanism by means of bolts.

8. The dynamic sealing rotary constant pressure filling device according to claim 7, characterized in that: A fourth conical surface is disposed at the inner upper end of the second friction seat, and the inclination direction of the fourth conical surface is opposite to the inclination direction of the second conical surface.

9. The dynamic sealing rotary constant pressure filling device according to claim 1, characterized in that: The material of the first friction seat is polyetheretherketone, and the material of the second friction seat is stainless steel.

10. The dynamic sealing rotary constant pressure filling device according to claim 1, characterized in that: The cone angle of the first friction seat is 40°, and the cone angle of the second friction seat is 38°.

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