Compound drink with functions of clearing away lung heat, moistening lung, diminishing inflammation and resisting bacteria and preparation process thereof

Abstract

The invention relates to the field of drinks, and particularly discloses a compound drink with functions of clearing away the lung heat, moistening the lung, diminishing inflammation and resisting bacteria and a preparation process of the compound drink. The invention relates to a compound drink with lung-heat-clearing, lung-moistening, inflammation-diminishing and antibacterial functions. Comprising the following raw materials in parts by weight: 70-90 parts of elderberry concentrated juice, 30-50 parts of Pesson berry powder, 8-12 parts of Laiyang pear syrup, 20-30 parts of acerola cherry powder, 6-10 parts of sophora flower bud composite microcapsules, 18-24 parts of roxburgh rose original juice, 0.1-0.3 part of roxburgh rose powder, 0.1-0.3 part of phyllanthus emblica powder, 0.1-0.3 part of mulberry powder, 0.1-0.3 part of spirulina platensis powder and the balance of purified water. The pagodatree flower bud composite microcapsule is prepared by wrapping a pagodatree flower bud extract and pagodatree flower bud powder with a water-soluble wall material. The compound drink has the effects of clearing away the lung-heat, moistening the lung, diminishing inflammation and resisting bacteria, and has good taste and stability.

Description

Technical Field

[0001] The present application relates to the field of beverages, and more specifically, to a compound beverage having the functions of clearing, moistening, reducing inflammation and resisting bacteria, and a preparation process thereof. Background Art

[0003] Modern pharmacological research has revealed that many natural plant ingredients contain rich bioactive substances, which have good anti-inflammatory and antibacterial performance. For example, flavonoids, polyphenols, alkaloids and other ingredients in certain Chinese herbal medicines have been proven to have significant antioxidant, anti-inflammatory and antibacterial effects, which can effectively improve the lung environment and enhance the lung's self-repair ability.

[0004] However, in practical applications, a problem that cannot be ignored is that many natural plant extracts with these biological activities, such as Sophora japonica extract, have poor water solubility. As a traditional Chinese medicinal material, Sophora japonica extract is rich in flavonoids and has significant lung-clearing, lung-moistening, anti-inflammatory and antibacterial effects. However, since Sophora japonica extract is insoluble in water, if it is directly added to purified water to prepare beverages, it often forms aggregates or precipitation, resulting in uneven distribution of Sophora japonica extract in the beverage.

[0005] This uneven distribution not only affects the taste and flavor of the beverage, causing consumers to feel uncomfortable such as granularity and foreign matter, but also may reduce the nutritional value of the beverage. At the same time, as time goes by, the water-insoluble Sophora japonica extract may also stratify and precipitate in the beverage, resulting in a decrease in the stability of the beverage. This not only affects the appearance and quality of the beverage, but may also shorten its shelf life and reduce consumer acceptance.

[0006] Therefore, in order to prepare a compound beverage that has both lung-clearing and lung-moisturizing, anti-inflammatory and antibacterial functions and good taste and stability, it is necessary to solve the problem of uniform dispersion and stable dissolution of insoluble ingredients such as Sophora japonica extract in the beverage. Summary of the invention

[0007] In order to improve the stability of the compound beverage, the present application provides a compound beverage with lung-clearing, lung-moistening, anti-inflammatory and antibacterial functions and a preparation process thereof.

[0008] In the first aspect, the present application provides a compound drink with lung-clearing, lung-moistening, anti-inflammatory and antibacterial functions, which adopts the following technical scheme: A compound drink with lung-clearing, lung-moistening, anti-inflammatory and antibacterial functions, comprising the following raw materials in parts by weight: The invention comprises 70-90 parts of concentrated elderberry juice, 30-50 parts of boysenberry powder, 8-12 parts of Laiyang pear paste, 20-30 parts of acerola powder, 6-10 parts of Sophora japonica composite microcapsules, 18-24 parts of original roxburghii juice, 0.1-0.3 parts of roxburghii powder, 0.1-0.3 parts of emblica powder, 0.1-0.3 parts of mulberry powder, 0.1-0.3 parts of pure top spirulina powder, and the balance is purified water; the Sophora japonica composite microcapsules are made of Sophora japonica extract and Sophora japonica powder wrapped with water-soluble wall materials.

[0009] By adopting the above technical scheme, elderberry concentrate juice and boysenberry powder are the main ingredients of the compound drink, which are rich in antioxidants and vitamins, can effectively remove lung free radicals, relieve respiratory inflammation, and achieve the effect of clearing and moistening the lungs. The addition of Laiyang pear paste further enhances the effect of moistening the lungs and relieving coughs, and has a positive effect on improving respiratory health and relieving symptoms such as coughs. Sophora japonica extract and acerola powder are rich in natural antibacterial ingredients, which can inhibit the growth and reproduction of bacteria and reduce the risk of infection. At the same time, Sophora japonica powder also has a certain anti-inflammatory effect, which can reduce respiratory inflammation, promote the disappearance of inflammation, and promote the absorption and utilization of flavonoids in Sophora japonica extract. These ingredients in the compound drink cooperate with each other to form a powerful anti-inflammatory and antibacterial system, which helps to protect lung health. Rosa roxburghii original juice and Rosa roxburghii powder are rich in vitamin C and various minerals, which can enhance the body's immunity and improve resistance. Phyllanthus emblica powder, mulberry powder and pure top spirulina powder are rich in various antioxidants and trace elements, which can supplement the nutrients needed by the human body and promote physical health. The addition of these ingredients makes the compound drink not only have the functions of clearing and moistening the lungs, reducing inflammation and antibacterial, but also provides comprehensive nutritional support for the human body.

[0010] Among them, Sophora japonica root, as a traditional Chinese medicinal material, has the effects of clearing heat and cooling blood, stopping bleeding and anti-inflammation, and plays an important role in compound drinks. However, the beneficial ingredients in its extracts, such as rutin and quercetin, are difficult to dissolve in water. They are not stable when preparing drinks, and the uneven dispersion affects the taste and nutritional value of the compound drink. Therefore, water-soluble wall materials are used to wrap them and then added to encapsulate the Sophora japonica root extract and Sophora japonica root powder in tiny capsules. These microcapsules can be evenly dispersed in water, avoiding the occurrence of agglomeration or precipitation, improving the taste and nutritional value of the compound drink, and also enhancing its anti-inflammatory and anti-inflammatory effects.

[0011] Optionally, the sophora japonica flower composite microcapsules are prepared by the following steps: (1) mixing a Sophora japonica extract with Sophora japonica powder to obtain a Sophora japonica composite powder, dissolving the Sophora japonica composite powder in an ethanol solution, adding an emulsifier and stirring to disperse the mixture to obtain a core material solution; preparing 5-8% by mass hydroxypropyltrimethylammonium chloride chitosan and sodium alginate solutions respectively and mixing the solutions to obtain a wall material solution; (2) slowly adding the core material solution to the wall material solution, stirring and emulsifying, so that the core material and the wall material are fully mixed to form a stable emulsion, adjusting the pH of the solution to 4.5-5.8 with acetic acid, reacting at 5-8°C for 10-20 minutes, spray drying, and cooling to room temperature to obtain Sophora japonica composite microcapsules.

[0012] By adopting the above technical scheme, in the preparation process of Sophora japonica composite microcapsules, the addition of emulsifiers and high-speed stirring ensure the full mixing and uniform dispersion of the core material and the wall material. Not only can the stability of the microcapsules in the compound drink be further improved, but the overall taste and uniformity of the drink can also be significantly improved, so that consumers can get a better drinking experience. As an important component of the compound drink, the Sophora japonica composite microcapsules can stably release effective ingredients that can synergize with other plant extracts (such as elderberry concentrate juice, boysenberry powder, etc.) to clear and moisturize the lungs. Hydroxypropyl trimethyl ammonium chloride chitosan and sodium alginate were selected as wall materials. Hydroxypropyl trimethyl ammonium chloride chitosan itself has good antibacterial and anti-inflammatory effects, which can further improve the antibacterial and anti-inflammatory properties of the compound drink, help reduce inflammatory reactions, promote the repair and regeneration of damaged tissues, and help improve lung health.

[0013] Optionally, the weight ratio of the Sophora japonica extract, Sophora japonica powder and emulsifier added to the core material solution is 5:0.1-0.3:3-5; The weight ratio of the hydroxypropyltrimethylammonium chloride chitosan solution to the sodium alginate solution is 2-3:5; The weight ratio of the core material solution to the wall material solution is 1:4-6.

[0014] By adopting the above technical scheme, the ratio of Sophora japonica extract to Sophora japonica powder ensures the content of active ingredients in the core material. At the same time, the addition of emulsifier can effectively reduce the surface tension of the solution, making the core material easier to disperse in the wall material solution to form a stable emulsion, thereby improving the stability of the microcapsule.

[0015] The appropriate ratio can form microcapsules with a compact structure, avoid leakage and loss of core material components, and improve the stability of microcapsules. The microcapsules finally prepared by selecting the above addition ratio have better comprehensive performance.

[0016] Optionally, the emulsifier is an aqueous solution prepared by dissolving starch phosphate in water, with a mass concentration of 0.4%-0.5%.

[0017] By adopting the above technical scheme, the emulsifier can form a protective layer on the surface of the droplets of Sophora japonica extract and Sophora japonica powder, thereby reducing the coagulation between them. Selecting starch phosphate as an emulsifier can more effectively reduce the surface tension of the solution, promote the uniform dispersion of Sophora japonica extract and Sophora japonica powder in the wall material solution, and at the same time improve the stability and biocompatibility of the microcapsules, optimize the taste and texture of the compound drink, and ensure the effective use of its healthy ingredients.

[0018] Optionally, the raw materials also include 0.1-0.2 parts of xanthan gum.

[0019] By adopting the above technical solution, xanthan gum has good emulsifying and suspending properties, which can make the different ingredients in the compound drink better mixed together to form a stable emulsion or suspension, and further improve the overall uniformity and stability of the drink.

[0020] Optionally, 0.2-0.4 parts of γ-cyclodextrin are also added to the raw materials.

[0021] By adopting the above technical solution, γ-cyclodextrin can mask or conceal the unpleasant flavors of certain raw materials, further improving the taste and flavor of the compound drink, while helping the active ingredients to be more evenly dispersed in the drink, thereby improving the stability of the entire drink.

[0022] Optionally, the raw materials include the following raw materials in parts by weight: The invention comprises 79-81 parts of concentrated elderberry juice, 39-41 parts of boysenberry powder, 9-11 parts of Laiyang pear paste, 24-26 parts of acerola powder, 7-9 parts of locust bean composite microcapsules, 19-21 parts of original roxburghii juice, 0.1-0.2 parts of roxburghii powder, 0.1-0.2 parts of emblica powder, 0.1-0.2 parts of mulberry powder, 0.1-0.2 parts of pure spirulina powder, 0.3-0.4 parts of gamma-cyclodextrin, and the balance is purified water; the locust bean composite microcapsules are made of locust bean extract and locust bean powder wrapped with water-soluble wall materials.

[0023] In the second aspect, the present application provides a method for preparing a compound drink having the functions of clearing the lungs, moistening the lungs, reducing inflammation and resisting bacteria, using the following technical scheme: A method for preparing a compound drink with lung-clearing, lung-moistening, anti-inflammatory and antibacterial functions comprises the following preparation steps: a. Mix boysenberry powder, acerola powder, roxburghii powder, emblica powder, mulberry powder and pure spirulina powder to form a solid mixture; b. Add purified water to the solid mixture and stir evenly to form a preliminary composite beverage solution; c. Add the Sophora japonica microcapsules, elderberry juice concentrate, roxburghii juice and Laiyang pear paste to the preliminary composite beverage solution, continue stirring and homogenizing; d. sterilizing the homogenized composite beverage solution, filling, sealing and labeling to obtain the composite beverage product.

[0024] In summary, this application has the following beneficial effects: 1. Since the present application forms a strong synergistic effect with the Sophora japonica composite microcapsules through a variety of natural plant extracts with lung-clearing and lung-moistening, anti-inflammatory and antibacterial functions such as elderberry concentrated juice, boysenberry powder, and Laiyang pear paste, the Sophora japonica composite microcapsules not only stably release the beneficial ingredients such as rutin and quercetin in the Sophora japonica, but also further enhance the anti-inflammatory and antibacterial effect of the composite drink through the antibacterial and anti-inflammatory effects of hydroxypropyltrimethylammonium chloride chitosan. The various natural plant ingredients in the composite drink cooperate with each other to form a powerful anti-inflammatory and antibacterial system, which helps to protect lung health. The stable release of the Sophora japonica composite microcapsules also enables these active ingredients to play a more effective role.

[0025] 2. The preferred compound drink in this application contains sophora japonica extract, acerola cherry powder and other natural antibacterial ingredients, which can inhibit the growth and reproduction of bacteria and form a powerful anti-inflammatory and antibacterial system. In particular, the addition of sophora japonica composite microcapsules, through its encapsulated microstructure, not only enables the effective ingredients to act more efficiently on the infected site, reduces the risk of infection, promotes the disappearance of inflammation and tissue repair, but also solves the problem of easy precipitation and agglomeration of the compound drink sophora japonica extract, and improves the stability and dispersibility of the sophora japonica extract and sophora japonica powder in the compound drink.

[0026] 3. The compound drink of the present application is also rich in a variety of nutrients that are beneficial to the human body, such as vitamin C and minerals in the original juice of roxburghii and roxburghii powder, antioxidant substances and trace elements in emblica powder, mulberry powder and pure spirulina powder, etc. The addition of these ingredients not only provides comprehensive nutritional support for the human body, but also can enhance the body's immunity, improve resistance, and further improve the anti-inflammatory and antibacterial capabilities of the compound drink.

[0027] 4. The uniform dispersion of Sophora japonica seed composite microcapsules makes the taste of the beverage more delicate, avoiding discomfort such as granularity and foreign body sensation, while retaining the natural flavor of various plant ingredients. DETAILED DESCRIPTION

[0028] The present application is further described in detail below with reference to the embodiments.

[0029] If the specific conditions are not specified in the examples, the experiments were carried out under conventional conditions or conditions recommended by the manufacturer. If the manufacturers of the reagents or instruments are not specified, they are all conventional products that can be purchased commercially.

[0030] Preparation examples of raw materials and / or intermediates Preparation Example 1 A kind of Sophora japonica flower composite microcapsule, the preparation comprises the following steps: (1) 20 g of Sophora japonica extract and 0.4 g of Sophora japonica powder were mixed to obtain Sophora japonica composite powder, which was dissolved in 120 g of ethanol solution, and 20 g of 0.5% phosphorylated distarch phosphate aqueous solution (emulsifier) ​​was added and stirred to disperse to obtain a core material solution, and 6.5% hydroxypropyl trimethyl ammonium chloride chitosan and 5% sodium alginate solutions were prepared respectively, and 56.28 g of hydroxypropyl trimethyl ammonium chloride chitosan solution was mixed with 93.72 g of sodium alginate solution to obtain a wall material solution; (2) 30 g of the core material solution was slowly added to the wall material solution, stirred and emulsified to allow the core material and the wall material to be fully mixed and form a stable emulsion, the pH of the solution was adjusted to 5.1 with acetic acid, reacted at 8° C. for 10 min, heated and spray-dried, and cooled to room temperature to obtain Sophora japonica composite microcapsules.

[0031] Preparation Example 2 A kind of Sophora japonica flower composite microcapsule, the preparation comprises the following steps: (1) 20 g of Sophora japonica extract and 0.2 g of Sophora japonica powder were mixed to obtain Sophora japonica composite powder, which was dissolved in 120 g of ethanol solution, and 16 g of 0.4% phosphorylated distarch phosphate aqueous solution (emulsifier) ​​was added and stirred to disperse to obtain a core material solution, and 5% hydroxypropyl trimethyl ammonium chloride chitosan and 8% sodium alginate solutions were prepared respectively, and 34.3 g of hydroxypropyl trimethyl ammonium chloride chitosan solution was mixed with 85.7 g of sodium alginate solution to obtain a wall material solution; (2) 30 g of the core material solution was slowly added to the wall material solution, stirred and emulsified to allow the core material and the wall material to be fully mixed and form a stable emulsion, the pH of the solution was adjusted to 4.5 with acetic acid, reacted at 6.5° C. for 15 min, heated and spray-dried, and cooled to room temperature to obtain Sophora japonica composite microcapsules.

[0032] Preparation Example 3 A kind of Sophora japonica flower composite microcapsule, the preparation comprises the following steps: (1) 20 g of Sophora japonica extract and 0.6 g of Sophora japonica powder were mixed to obtain Sophora japonica composite powder, which was dissolved in 120 g of ethanol solution, and 12 g of 0.5% phosphorylated distarch phosphate aqueous solution (emulsifier) ​​was added and stirred to obtain a core material solution, and 6.5% hydroxypropyl trimethyl ammonium chloride chitosan and 5% sodium alginate solutions were prepared respectively, and 60 g of hydroxypropyl trimethyl ammonium chloride chitosan solution was mixed with 120 g of sodium alginate solution to obtain a wall material solution; (2) 30 g of the core material solution was slowly added to the wall material solution, stirred and emulsified to fully mix the core material and the wall material to form a stable emulsion, the pH of the solution was adjusted to 4.5 with acetic acid, reacted at 6°C for 20 min, heated and spray-dried, and cooled to room temperature to obtain Sophora japonica composite microcapsules.

[0033] Preparation Example 4 A sophora japonica seed composite microcapsule, which is different from Preparation Example 1 in that the wall material solution in this Preparation Example is a sodium alginate solution, and the preparation comprises the following steps: (1) 20 g of Sophora japonica extract and 0.4 g of Sophora japonica powder were mixed to obtain Sophora japonica composite powder, which was dissolved in 120 g of ethanol solution, and 20 g of starch phosphate (emulsifier) ​​was added and stirred to obtain a core material solution, and a sodium alginate solution with a mass fraction of 5% was prepared to obtain a wall material solution; (2) 30 g of the core material solution and 150 g of the wall material solution were taken, and the core material solution was slowly added to the wall material solution, and the core material and the wall material were stirred and emulsified to fully mix and form a stable emulsion. The pH of the solution was adjusted to 5.1 with acetic acid, and the reaction was carried out at 8° C. for 10 min, and then the temperature was raised and spray-dried, and the mixture was cooled to room temperature to obtain Sophora japonica composite microcapsules.

[0034] Preparation Example 5 A sophora japonica flower composite microcapsule, which is different from Preparation Example 1 in that the emulsifier used in this Preparation Example is an aqueous solution of sodium dodecyl sulfate. Example

[0035] Example 1 A compound drink with lung-clearing, lung-moistening, anti-inflammatory and antibacterial functions, the preparation of which comprises the following steps: a. Mix 40g of Boysenberry powder, 25g of Acerola powder, 0.2g of Rosa roxburghii powder, 0.1g of Phyllanthus emblica powder, 0.1g of mulberry powder, and 0.1g of pure Spirulina powder to form a solid mixture; b. Add 816.5 g of purified water to the solid mixture and stir to form a preliminary composite beverage solution; c. Add 8g of Sophora japonica microcapsules, 80g of elderberry juice concentrate, 20g of roxburghii juice and 10g of Laiyang pear paste to the preliminary composite drink solution, continue stirring and homogenizing; d. Sterilize the homogenized composite beverage solution, then fill, seal and label it to obtain the composite beverage product. The composite microcapsules of Sophora japonica seed are prepared in Preparation Example 1.

[0036] Example 2-3 A compound drink with lung clearing, moistening, anti-inflammatory and antibacterial functions, which is different from Example 1 in that its raw material components and their corresponding weight portions are shown in Table 1, and the Sophora japonica seed composite microcapsules used are prepared in Preparation Examples 2 and 3 respectively.

[0037] Table 1 Raw materials and their weights in Examples 1-3 (g) Example 4 A compound drink with lung clearing, lung moistening, anti-inflammatory and antibacterial functions, which is different from Example 1 in that the sophora japonica flower complex microcapsules are prepared in Preparation Example 4.

[0038] Example 5 A compound drink with lung clearing, lung moistening, anti-inflammatory and antibacterial functions, which is different from Example 1 in that the sophora japonica flower complex microcapsules are prepared in Preparation Example 5.

[0039] Example 6 A composite drink with lung-clearing, lung-moistening, anti-inflammatory and antibacterial functions, which is different from Example 1 in that 0.1 g of xanthan gum is further added to the raw materials and added to the solid mixture. The preparation differences are as follows: a. 40 g of boysenberry powder, 25 g of acerola powder, 0.2 g of roxburghii powder, 0.1 g of emblica powder, 0.1 g of mulberry powder, 0.1 g of pure spirulina powder and 0.1 g of xanthan gum were mixed to form a solid mixture; the remaining steps were the same as in Example 1.

[0040] Example 7 A compound drink with lung-clearing, lung-moistening, anti-inflammatory and antibacterial functions, which is different from Example 6 in that 0.2 g of xanthan gum is added.

[0041] Example 8 A compound drink with lung-clearing, lung-moistening, anti-inflammatory and antibacterial functions, which is different from Example 1 in that 0.2 g of γ-cyclodextrin is further added to the raw materials and added to the solid mixture. The preparation differences are as follows: a. 40 g of boysenberry powder, 25 g of acerola powder, 0.2 g of roxburghii powder, 0.1 g of emblica powder, 0.1 g of mulberry powder, 0.1 g of pure spirulina powder and 0.2 g of γ-cyclodextrin were mixed to form a solid mixture; the remaining steps were the same as in Example 1.

[0042] Example 9 A compound drink with lung-clearing, lung-moistening, anti-inflammatory and antibacterial functions, which is different from Example 8 in that 0.4 g of γ-cyclodextrin is added.

[0043] Comparative Example Comparative Example 1 A compound drink with lung-clearing, lung-moistening, anti-inflammatory and antibacterial functions, which is different from Example 1 in that in this comparative example, the sophora japonica extract and sophora japonica powder are not made into microcapsules, but are directly added to the raw materials in powder form, and the preparation comprises the following steps: a. 40g Boysenberry powder, 25g Acerola powder, 0.2g Rosa roxburghii powder, 0.1g Phyllanthus emblica powder, 0.1g mulberry powder, 0.1g pure Spirulina powder, 5g Sophora japonica extract and 0.1g Sophora japonica powder were mixed to form a solid mixture; b. Add 816.5 g of purified water to the solid mixture and stir to form a preliminary composite beverage solution; c. Add 80g of elderberry juice concentrate, 20g of roxburghii juice and 10g of Laiyang pear paste to the preliminary composite drink solution, continue stirring and homogenizing; d. sterilizing the homogenized composite beverage solution, filling, sealing and labeling to obtain the composite beverage product.

[0044] Comparative Example 2 A compound drink with lung clearing, lung moistening, anti-inflammatory and antibacterial functions, which is different from Example 1 in that no acerola cherry powder is added in this comparative example.

[0045] Comparative Example 3 A compound drink with lung-clearing, lung-moistening, anti-inflammatory and antibacterial functions, which is different from Example 1 in that no original squeezed fruit juice of roxburghii is added in this comparative example.

[0046] Comparative Example 4 A compound drink with lung clearing, lung moistening, anti-inflammatory and antibacterial functions, which is different from Example 1 in that boysenberry powder is not added in this comparative example.

[0047] Comparative Example 5 A compound drink with lung clearing, lung moistening, anti-inflammatory and antibacterial functions, which is different from Example 1 in that elderberry concentrated juice is not added in this comparative example.

[0048] Performance testing Detection method / test method Sensory evaluation: Please ask people from 5-17 years old, 18-25 years old, 26-45 years old, 46-60 years old to form an evaluation team, and score the sensory indicators of the product with reference to the sensory evaluation method in Table 1. The 15-point scoring principle is adopted. The larger the value, the better the sensory quality of the product, and the more people will accept and like it.

[0049] Table 2 Stability: Take 10mL of the compound drink, centrifuge at 5000r / min for 10min, measure the absorbance A1 before centrifugation and the absorbance A0 of the supernatant after centrifugation at 660nm, and use distilled water as blank. Calculate the stability according to R=A0 / A1, where: A0 is the absorbance of the supernatant at 660nm after centrifugation; A1 is the absorbance of the drink at 660nm before centrifugation; R is the ratio of the absorbance before and after centrifugation, indicating stability. The larger the R value, the better the stability.

[0050] Anti-inflammatory effect: Male ICR mice were purchased and randomly divided into an experimental group (daily gavage of 20 ml / kg·d) and a blank group (normal saline 20 mL / kg·d). Gavage was continued for 2 weeks. One hour after the last gavage, 20 μL of xylene was evenly applied on the front and back of the left ear of the mice to induce inflammation. After 30 minutes, blood was collected from the canthus of the mice and centrifuged at 3500 r / min at 4°C for 10 minutes to separate the serum. The ELISA method was used to detect the levels of TNF-α and IL-1β. For specific methods, please refer to the instruction manual of the kit.

[0051] Table 3 Test results stability / % TNF-α(pg / mL) IL-1β (pg / mL) Example 1 98.1 15.0 2.5 Example 2 97.8 14.8 2.4 Example 3 98.0 15.2 2.3 Example 4 95.6 16.5 3.4 Example 5 96.1 16.1 3.2 Example 6 98.5 14.5 2.2 Example 7 98.3 14.7 2.1 Example 8 98.6 14.4 2 Example 9 98.8 14.6 2.1 Comparative Example 1 88.9 19.4 4.0 Comparative Example 2 97.5 20.2 4.5 Comparative Example 3 97.8 20.5 4.8 Comparative Example 4 97.6 19.8 4.1 Blank group / 27.12 10.23 Table 4 Sensory test results Combining Examples 1-3 and Comparative Example 1 and Tables 3 and 4, it can be seen that the experimental data of Example 1 are all better than those of Comparative Example 1, indicating that after the Sophora japonica extract and Sophora japonica powder are microencapsulated using the method provided by the present application, the lung-clearing, lung-moisturizing, anti-inflammatory and antibacterial effects of the composite drink can be significantly improved. Microencapsulation technology not only improves the stability of the active ingredients in Sophora japonica, but also enhances its dispersibility and bioavailability in the composite drink, so that the composite drink has a better taste and a better anti-inflammatory effect.

[0052] When no acerola cherry powder, roxburgh original juice, boysenberry powder and elderberry concentrated juice were added to comparative examples 2-5, the effects were reduced and the anti-inflammatory and antibacterial effects were not significant, indicating that the several active ingredients in the present application need to be combined together to have more significant lung clearing, moisturizing, anti-inflammatory and antibacterial effects.

[0053] It can be seen from Examples 1-4 and Tables 3 and 4 that the experimental data of Examples 1-3 are better than those of Example 4, indicating that the microcapsule wall material prepared by compounding hydroxypropyltrimethylammonium chloride chitosan with sodium alginate solution can improve the stability and biocompatibility of Sophora japonica extract and Sophora japonica powder in the compound drink, and the antibacterial and anti-inflammatory effect of hydroxypropyltrimethylammonium chloride chitosan further improves the antibacterial and anti-inflammatory ability of the compound drink.

[0054] It can be seen from Examples 1-5 and Tables 3 and 4 that the experimental data of Examples 1-4 are better than those of Example 5, indicating that the microcapsules prepared using starch phosphate aqueous solution as an emulsifier have better suspension and stability in the compound drink than other emulsifiers.

[0055] Combining Example 1 with Examples 6-7 and Tables 3 and 4, it can be seen that the experimental data of Examples 6-7 are better than those of Example 1, indicating that the suspension and stability of the compound drink with the addition of xanthan gum are further improved.

[0056] Combining Example 1 with Examples 8-9 and Tables 3 and 4, it can be seen that the experimental data of Examples 8-9 are better than those of Example 1, indicating that the addition of γ-cyclodextrin can help the active ingredients to be more evenly dispersed in the beverage, improve its stability, and improve the taste and flavor of the compound beverage.

[0057] This specific embodiment is merely an explanation of the present application and is not a limitation of the present application. After reading this specification, those skilled in the art may make modifications to the present embodiment without any creative contribution as needed, but such modifications are protected by the patent law as long as they are within the scope of the claims of the present application.

Claims

1. A compound drink with lung-clearing, lung-moistening, anti-inflammatory and antibacterial functions, characterized in that: The composition comprises the following raw materials in parts by weight: The invention comprises 70-90 parts of concentrated elderberry juice, 30-50 parts of boysenberry powder, 8-12 parts of Laiyang pear paste, 20-30 parts of acerola powder, 6-10 parts of Sophora japonica composite microcapsules, 18-24 parts of original roxburghii juice, 0.1-0.3 parts of roxburghii powder, 0.1-0.3 parts of emblica powder, 0.1-0.3 parts of mulberry powder, 0.1-0.3 parts of pure top spirulina powder, and the balance is purified water; the Sophora japonica composite microcapsules are made of Sophora japonica extract and Sophora japonica powder wrapped with water-soluble wall materials.

2. A compound drink with lung-clearing, lung-moistening, anti-inflammatory and antibacterial functions according to claim 1, characterized in that: The sophora japonica flower composite microcapsules are prepared by the following steps: (1) Mixing a Sophora japonica extract with Sophora japonica powder to obtain a Sophora japonica composite powder, dissolving the Sophora japonica composite powder in an ethanol solution, adding an emulsifier and stirring to disperse the mixture to obtain a core material solution; preparing 5-8% by mass hydroxypropyltrimethylammonium chloride chitosan and sodium alginate solutions respectively and mixing the solutions to obtain a wall material solution; (2) Slowly add the core material solution to the wall material solution, stir and emulsify, so that the core material and the wall material are fully mixed to form a stable emulsion, adjust the pH of the solution to 4.5-5.8 with acetic acid, react at 5-8°C for 10-20 minutes, spray dry, and cool to room temperature to obtain Sophora japonica composite microcapsules.

3. A compound drink with lung-clearing, lung-moistening, anti-inflammatory and antibacterial functions according to claim 2, characterized in that: The weight ratio of the Sophora japonica extract, Sophora japonica powder and emulsifier in the core material solution is 5:0.1-0.3:3-5; The weight ratio of the hydroxypropyltrimethylammonium chloride chitosan solution to the sodium alginate solution is 2-3:5; The weight ratio of the core material solution to the wall material solution is 1:4-6.

4. The compound drink with lung-clearing, lung-moistening, anti-inflammatory and antibacterial functions according to claim 1, characterized in that: The emulsifier is an aqueous solution prepared by dissolving starch phosphate in water, and the mass concentration is 0.4%-0.5%.

5. The compound drink with lung-clearing, lung-moistening, anti-inflammatory and antibacterial functions according to claim 1, characterized in that: The raw materials also include 0.1-0.2 parts of xanthan gum.

6. The compound drink with lung-clearing, lung-moistening, anti-inflammatory and antibacterial functions according to claim 1, characterized in that: 0.2-0.4 parts of gamma-cyclodextrin are also added to the raw materials.

7. The compound drink with lung-clearing, lung-moistening, anti-inflammatory and antibacterial functions according to claim 6, characterized in that: The raw materials include the following raw materials in parts by weight: The invention comprises 79-81 parts of concentrated elderberry juice, 39-41 parts of boysenberry powder, 9-11 parts of Laiyang pear paste, 24-26 parts of acerola powder, 7-9 parts of locust bean composite microcapsules, 19-21 parts of original roxburghii juice, 0.1-0.2 parts of roxburghii powder, 0.1-0.2 parts of emblica powder, 0.1-0.2 parts of mulberry powder, 0.1-0.2 parts of pure spirulina powder, 0.3-0.4 parts of gamma-cyclodextrin, and the balance is purified water; the locust bean composite microcapsules are made of locust bean extract and locust bean powder wrapped with water-soluble wall materials.

8. A process for preparing a compound drink having lung-clearing, lung-moistening, anti-inflammatory and antibacterial functions according to any one of claims 1 to 4, characterized in that: The method comprises the following preparation steps: a. Mix boysenberry powder, acerola powder, roxburghii powder, emblica powder, mulberry powder and pure spirulina powder to form a solid mixture; b. Add purified water to the solid mixture and stir evenly to form a preliminary composite beverage solution; c. Add the Sophora japonica microcapsules, elderberry juice concentrate, roxburghii juice and Laiyang pear paste to the preliminary composite beverage solution, continue stirring and homogenizing; d. sterilizing the homogenized composite beverage solution, filling, sealing and labeling to obtain the composite beverage product.

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