Experimental pill dropping machine and preparation method of dropping pills

Abstract

The invention discloses an experimental pill dropping machine. The experimental pill dropping machine comprises a dropping funnel, a control unit and a coolant circulating device, the control unit is placed on the shelf and comprises a heating body temperature controller, a refrigeration temperature controller, a circulating pump control switch and a main switch; the outer side of the drip chamber is coated with a heating body, the heating body is electrically connected with a heating body temperature controller, the bottom of the drip chamber is connected with a drip opening, and a control valve is arranged on the drip opening; the coolant circulating device comprises a condenser pipe, a coolant box and a circulating pump, the condenser pipe comprises a straight condenser pipe and a curved condenser pipe, and the straight condenser pipe is connected with the curved condenser pipe; the coolant box comprises a box body and a refrigeration mechanism used for cooling a coolant in the box body, a first opening and a second opening are formed in the top of the box body, and a screen disc is placed at the top of the first opening; the coolant box is connected with an inlet of the circulating pump; the circulating pump is connected with the circulating pump control switch, and an outlet of the circulating pump is connected with the straight condenser pipe.

Description

Technical Field

[0001] The invention relates to the technical field of dropping pill machines, in particular to an experimental dropping pill machine and a method for preparing the dropping pills. Background Art

[0002] The pill machine is a kind of pharmaceutical preparation machinery, which is used in food, medicine, chemical industry, metal and other industries. The pill is a unique dosage form in China's pharmaceutical industry, which is of great significance to the development and application of Chinese herbal medicine dosage forms and has a broad research space.

[0003] At present, the pill machines on the market all use compressor refrigeration systems, which require a large space inside the machine. At the same time, the feeding tank and cooling column are large in size, which consumes a lot of materials during use and takes a long time to test. It is not suitable for universities or research institutions that need a smaller test system when doing formulation research, resulting in a waste of materials and time.

[0004] At the same time, in the actual production process, the droplet speed is often affected by many factors, such as liquid viscosity, ambient temperature and mechanical vibration. If the droplet speed cannot be effectively monitored and adjusted, it may lead to different sizes of droplets and inaccurate drug dosage, thus affecting the efficacy and safety of the drug. Especially in the production of high-precision and high-standard drugs, the control requirements for the droplet speed are more stringent. Summary of the invention

[0005] The purpose of this invention is to provide an experimental dropping pill machine and a method for preparing dropping pills in order to solve the problems that the existing dropping pill machines are large in size and not suitable for scientific research experiments and the droplet speed cannot be effectively controlled.

[0006] The technical solution adopted to achieve the purpose of the present invention is:

[0007] An experimental pill dropping machine comprises a dropping bucket, a control unit and a coolant circulation device;

[0008] The control unit is placed on the shelf, and the control unit includes a heating body thermostat, a cooling thermostat, a circulation pump control switch and a main switch;

[0009] The outer side of the drip bucket is covered with a heater, the heater is electrically connected to a heater temperature controller to control the heating temperature of the heater, the bottom of the drip bucket is connected to a drip port, and the drip port is provided with a control valve for controlling the size of drug droplets;

[0010] The coolant circulation device comprises a condenser, a coolant tank and a circulation pump, wherein the condenser comprises a straight condenser and a curved condenser, wherein the straight condenser is connected to the curved condenser, wherein the top opening of the straight condenser is located directly below the drip bucket, and the outlet of the curved condenser is located above the coolant tank;

[0011] The coolant box comprises a box body and a refrigeration mechanism for cooling the coolant in the box body, the top of the box body is provided with a first opening and a second opening, and a mesh plate for filtering the pellets flowing out of the curved condenser tube is placed on the top of the first opening;

[0012] The coolant tank is connected to the inlet of the circulation pump through an input pipeline; the circulation pump is connected to a circulation pump control switch to control the circulation pump switch, and the outlet of the circulation pump is connected to the straight condenser through an output pipeline.

[0013] In the above technical scheme, the experimental pill machine also includes a bracket and a base, the bracket includes a first bracket, a second bracket and a third bracket, the first bracket, the second bracket and the third bracket are respectively fixedly mounted on the base; the shelf is fixedly mounted on the third bracket; the drip bucket is mounted on the first bracket through a first fixing clamp; the shelf is fixedly mounted on the third bracket; the straight condenser is mounted on the first bracket through a second fixing clamp, and the curved condenser is mounted on the first bracket through a third fixing clamp; the coolant tank is fixedly mounted on the second bracket through a fourth fixing clamp.

[0014] In the above technical solution, the lower side wall of the straight condenser is detachably connected with a glass bend tube, and the outlet of the glass bend tube is fixedly connected to the inlet of the curved condenser.

[0015] In the above technical solution, the outlet of the circulation pump is connected to an output pipeline, and the other end of the output pipeline is connected to the straight condenser through a glass elbow.

[0016] In the above technical solution, a heat-insulating layer for keeping the coolant in the box warm is provided on the outer side of the box.

[0017] In the above technical scheme, the refrigeration mechanism is a semiconductor refrigeration system or a compressor refrigeration system, and the semiconductor refrigeration system includes a semiconductor refrigeration temperature control probe, a semiconductor refrigeration sheet, a heat sink fin and a fan. The semiconductor refrigeration temperature control probe enters from the second opening and contacts the coolant in the box body. The semiconductor refrigeration temperature control probe is connected to the refrigeration temperature controller to control the cooling temperature; the semiconductor refrigeration sheet is fixedly installed on the side wall and / or the bottom of the box body, and a mounting hole is formed in the middle position of the semiconductor refrigeration sheet. The fourth bracket passes through the mounting hole and is fixedly installed on the bottom of the box body. Multiple groups of heat sink fins are symmetrically installed on both sides of the fourth bracket, and a fan is fixedly installed in the middle position of the multiple groups of heat sink fins to cool the heat sink.

[0018] In the above technical solution, the circulation pump is a diaphragm pump.

[0019] In the above technical solution, the experimental pill machine also includes a counting and speed measurement control system, which includes a controller and a counting sensor, a servo and a touch screen electrically connected to the controller. The counting sensor is used to obtain real-time information on the dripping of the drug at the dripping mouth. The controller is electrically connected to the servo to control the rotation angle of the servo, and the opening of the control valve is controlled by controlling the rotation angle of the servo.

[0020] In the above technical solution, the controller is an STM32 controller.

[0021] A method for preparing dropping pills using an experimental dropping pill machine comprises the following steps:

[0022] Step 1, using a semiconductor refrigeration temperature control probe to detect the temperature of the coolant inside the box. If the temperature of the coolant inside the box does not meet the standard, the semiconductor refrigeration chip is connected through the refrigeration thermostat, and the semiconductor refrigeration chip is used to exchange heat with the coolant inside the box. The fan is started, and the heat dissipation fins are used to dissipate heat and cool the semiconductor refrigeration chip, thereby exchanging heat and cooling the coolant inside the box to make the coolant temperature meet the standard;

[0023] Step 2, turning on the circulating pump through the circulating pump control switch, and using the circulating pump to pump the coolant with the temperature reaching the standard inside the box into the straight condenser tube, so that the coolant height in the straight condenser tube and the curved condenser tube reaches a preset height;

[0024] Step 3, pouring the melted medicine into the dripping funnel, setting the heating temperature of the heating body to heat the medicine in the dripping funnel, and when the heating body thermostat detects that the temperature of the medicine in the dripping funnel reaches the dripping requirement, using the control valve to control the medicine dripping port switch, so that the medicine in the dripping funnel drips into the straight condenser through the dripping port, and using the coolant in the straight condenser to quickly cool the medicine to form dripping pills;

[0025] Step 4, the pellets formed in the straight condenser tube flow out to the curved condenser tube along with the coolant, and flow out to the mesh plate along the curved condenser tube, the pellets are trapped in the mesh plate, and the coolant flows into the box through the mesh plate, and steps 1-2 are repeated again to realize the recycling of the coolant;

[0026] Step 5, remove the sieve plate and pour the pellets into a storage container to complete the preparation of the pellets.

[0027] Compared with the prior art, the present invention has the following beneficial effects:

[0028] 1. The experimental pill making machine of the present invention is small in size, can prepare qualified pills, and each component can be flexibly disassembled.

[0029] 2. The refrigeration mechanism of the present invention adopts a semiconductor structure, which can better control the temperature and increase the refrigeration speed, and does not need to add refrigerants such as Freon, which is beneficial to environmental protection.

[0030] 3. The experimental pill machine of the present invention also includes a counting and speed measurement control system, which can monitor the dripping speed of the experimental pill machine in real time, and automatically adjust the opening of the control valve according to the actually measured dripping speed to keep the dripping speed of the experimental pill machine within the set target range, which can significantly improve the stability and consistency of the experimental pill production and ensure the high-quality production of the drug; the touch screen also displays a touch option for manually adjusting the servo angle, which can enable the operator to directly control the drug dripping speed. BRIEF DESCRIPTION OF THE DRAWINGS

[0031] Figure 1 Shown is a structural diagram of an experimental pill dropping machine of the present invention.

[0032] Figure 2 Shown is a disassembled structural diagram of the experimental pill-dropping machine of the present invention.

[0033] In the figure: 1-drip bucket, 11-heating body, 111-temperature controller, 12-control valve, 13-drip port, 2-condenser, 21-straight condenser, 211-inlet, 22-curved condenser, 3-coolant tank, 31-screen plate, 32-semiconductor refrigeration sheet, 34-heat dissipation fins, 35-fan, 36-semiconductor refrigeration temperature control probe, 37-box, 371-thermal insulation layer, 38-first opening, 39-second opening, 4-circulating pump 41-oil drain valve, 51-first fixing clamp, 52-second fixing clamp, 53-third fixing clamp, 6-first bracket, 7-base, 8-second bracket, 9-input pipeline, 10-output pipeline. DETAILED DESCRIPTION

[0034] The present invention is further described in detail below in conjunction with specific embodiments. It should be understood that the specific embodiments described herein are only used to explain the present invention and are not used to limit the present invention.

[0035] Example 1

[0036] An experimental pill dropping machine, see Figure 1 , Figure 2 , including a drip bucket 1, a bracket, a control unit, a coolant circulation device and a base 7; the bracket includes a first bracket 6, a second bracket 8 and a third bracket, and the first bracket 6, the second bracket 8 and the third bracket are fixedly mounted on the base 7 respectively.

[0037] The control unit is placed on a shelf, and the shelf is fixedly mounted on a third bracket, wherein the control unit includes a heating body thermostat, a cooling thermostat, a circulation pump control switch and a main switch.

[0038] The drip bucket 1 is installed on the first bracket 6 by a detachable first fixing clip 51, and the first fixing clip 51 can drive the drip bucket 1 to move up and down along the first bracket 6; the outer side of the drip bucket 1 is covered with a heating body 11, and the heating body 11 is electrically connected to a heating body thermostat, and the heating body thermostat can be used to control the heating temperature of the heating body, thereby controlling the temperature of the drip bucket 1. The heating body 11 is preferably an electrically heated mica sheet, and the heating body 11 can also be other heating bodies; a drip outlet 13 is connected to the bottom of the drip bucket 1, and a control valve 12 is provided on the drip outlet 13 for controlling the droplet size of the drug.

[0039] The coolant circulation device includes a condenser 2 , a coolant tank 3 and a circulation pump 4 .

[0040] The condenser 2 includes a straight condenser 21 and a curved condenser 22. The straight condenser 21 is installed on the first bracket 6 through a second fixing clamp 52, and the curved condenser 22 is installed on the first bracket 6 through a third fixing clamp 53. The lower side wall of the straight condenser 21 is detachably connected (or integrated) with a glass bend, and the outlet of the glass bend is fixedly connected to the inlet of the curved condenser 22. The top opening of the straight condenser 21 is located directly below the drip bucket 1, so that the medicine in the drip bucket 1 that reaches the dripping requirement can be dripped into the straight condenser 21, cooled in the straight condenser 21 to form droplets, and the droplets flow out into the glass bend along with the coolant, and then flow into the curved condenser 22 through the glass bend, and flow out along the curved condenser 22 along with the coolant; the straight condenser 21 and the curved condenser 22 are made of glass or acrylic; the outlet of the curved condenser 22 is located above the coolant tank 3.

[0041] The coolant tank 3 is fixedly mounted on the second bracket 8 by a fourth fixing clamp. The coolant tank 3 includes a tank body 37 and a refrigeration mechanism for cooling the coolant in the tank body. The top of the tank body 35 is provided with a first opening 38 and a second opening 39. A mesh plate 31 is placed on the top of the first opening 38 for filtering the droplets flowing out of the curved condenser 22 and allowing the coolant to flow into the tank body 35. The refrigeration mechanism is a semiconductor refrigeration system or a compressor refrigeration system. The semiconductor refrigeration system includes a semiconductor refrigeration temperature control probe 36, a semiconductor refrigeration sheet 32, a heat sink fin 34 and a fan 35. The semiconductor refrigeration temperature control probe 36 enters from the second opening 39 and is fixedly mounted on the inner wall of the tank body 35, in contact with the coolant in the tank body 35, and is used to detect the inside of the tank body 37. The temperature of the coolant; the semiconductor refrigeration temperature control probe 36 is connected to the refrigeration thermostat, and is used to feed back the detected temperature of the coolant inside the box 37 to the refrigeration thermostat, and the cooling temperature of the semiconductor refrigeration plate 32 is controlled by the refrigeration thermostat. The semiconductor refrigeration plate 32 is fixedly installed on the side wall and / or the bottom of the box 37, and is used to cool the coolant in the box 35. The top of the semiconductor refrigeration plate 32 is completely in contact with the bottom surface of the box 37; a mounting hole is formed in the middle position of the semiconductor refrigeration plate 32, and the fourth bracket is fixedly installed on the bottom of the box 37 through the mounting hole, and multiple groups of heat dissipation fins 34 are symmetrically installed on both sides of the fourth bracket, and a fan 35 is fixedly installed in the middle position of the multiple groups of heat dissipation fins 34, and the heat dissipation fins 34 are used to dissipate heat and cool the semiconductor refrigeration plate 32.

[0042] Furthermore, the box body 37 is made of metal, which can better complete the heat exchange between the semiconductor refrigeration plate 32 and the coolant in the box body 37; the outer side of the box body 37 is provided with a thermal insulation layer 371 for insulating the coolant in the box body 37; the semiconductor refrigeration plate 32 is located between the side wall of the box body 37 and the thermal insulation layer 371; each heat pipe is snapped into place with the semiconductor refrigeration plate 32 through a metal seat snap-on.

[0043] The coolant tank 3 is connected to the inlet of the circulation pump 4 through the input pipeline 9, and is used to pump out the cooled coolant in the tank 37; the circulation pump 4 is connected to the circulation pump control switch, and the circulation pump switch is controlled by the circulation pump control switch; the outlet of the circulation pump 4 is connected to the output pipeline 10, and the other end of the output pipeline 10 is connected to the straight condenser 21 through a glass bend pipe, and is used to pump the cooled coolant into the straight condenser 21 to achieve the recycling of the coolant. Among them, the circulation pump 4 is a diaphragm pump. Among them, the input pipeline 8 is connected to the coolant tank 3 through the oil drain valve 41, and the output pipeline 9 is connected to the straight condenser 21 through the coolant inlet 211.

[0044] Example 2

[0045] Based on Example 1, a method for preparing an experimental dropping pill comprises the following steps:

[0046] Step 1, use the semiconductor refrigeration temperature control probe 36 to detect the temperature of the coolant inside the box 37. If the temperature of the coolant inside the box 37 does not meet the standard, the semiconductor refrigeration plate 32 is connected through the refrigeration thermostat 36, and the semiconductor refrigeration plate 32 is used to exchange heat with the coolant inside the box 37. The fan is started and the heat dissipation fins 34 are used to dissipate heat and cool down the semiconductor refrigeration plate 32, thereby exchanging heat and cooling the coolant inside the box 37 to make the coolant temperature meet the standard.

[0047] Step 2, turn on the circulation pump through the circulation pump control switch, and use the circulation pump 4 to pump the coolant with the temperature reaching the standard inside the box 37 into the straight condenser 21, so that the coolant height in the straight condenser 21 and the curved condenser 22 reaches a preset height (a height suitable for dripping medicine).

[0048] Step 3, pour the melted medicine into the dripping funnel 1, set the heating temperature of the heating body 11 to heat the medicine in the dripping funnel 1, and when the heating body thermostat detects that the temperature of the medicine in the dripping funnel 1 reaches the dripping requirement, use the control valve 12 to control the medicine dripping port switch, so that the medicine in the dripping funnel 1 drips into the straight condenser 21 through the dripping port 13, and uses the coolant in the straight condenser 21 to quickly cool the medicine to form dripping pills.

[0049] In step 4, the pellets formed in the straight condenser 21 flow out to the curved condenser 22 along with the coolant, and flow out to the mesh plate 31 along the curved condenser 22. The pellets are retained in the mesh plate 31, and the coolant flows into the box 37 through the mesh plate 31. Steps 1-2 are performed again to realize the recycling of the coolant.

[0050] Step 5, remove the sieve plate 31 and pour the pellets into a storage container, thus completing the preparation of the pellets.

[0051] Example 3

[0052] On the basis of Example 1, a plurality of heat pipes may be symmetrically arranged on the bottom surface of the semiconductor cooling sheet 32 ​​for heat exchange with the semiconductor cooling sheet 32. The fan is turned on, and the heat dissipation fins 34 are used to dissipate heat from the heat pipes and the semiconductor cooling sheet 32, thereby achieving heat exchange and cooling of the coolant inside the box 37, so that the temperature of the coolant meets the standard and the heat dissipation efficiency is increased. The diameter and number of the heat pipes are set according to the experimental requirements. The larger the diameter and the more the number of heat pipes, the higher the cooling efficiency.

[0053] Example 4

[0054] On the basis of Example 1, the experimental pill machine also includes a counting and speed measurement control system, which is connected to the control valve 12 and is used to monitor the dripping rate of the experimental pill machine in real time, and automatically or manually adjust the opening of the control valve 12 according to the monitored dripping rate to control the dripping speed of the drug.

[0055] The counting and speed control system includes a controller (the controller is preferably an STM32 controller, i.e., STM32F407VGT6) and a counting sensor, a servo and a touch screen electrically connected to the controller. The counting sensor is used to obtain real-time information of drug dripping at the drip outlet 13. The controller is electrically connected to the servo to control the rotation angle of the servo, and the opening of the control valve 12 is controlled by controlling the rotation angle of the servo.

[0056] The counting sensor is used to obtain real-time information of drug dripping at the dripping port 13, and output a signal according to the real-time information of drug dripping, wherein when the counting sensor detects drug dripping, the output signal is a PNP signal (low level), and when the counting sensor does not detect drug dripping, the output signal is an NPN signal (high level), and the NPN signal and the NPN signal are a common sensor output type. The controller reads the real-time information of drug dripping obtained by the counting sensor, calculates the amount and speed of drug dripping according to the real-time information of drug dripping, and automatically adjusts the opening of the control valve 12 according to the speed of drug dripping and using the PID control algorithm (servo control algorithm), that is, automatically adjusts the speed of drug dripping.

[0057] The counting sensor of this embodiment is preferably a QL2932 photoelectric sensor, whose parameters can sense the needs of experimental pills. Among them, the QL2932 photoelectric sensor has a detection range of 29mm×32mm and a detection accuracy of >2mm, which can accurately detect experimental pills with a minimum diameter of 2mm, meeting the detection requirements of the experimental pill machine, and the response time of 1.4ms ensures that the sensor can quickly capture the passage of each droplet, thereby providing reliable data support for real-time speed calculation; the NPN output signal of the QL2932 photoelectric sensor is captured by the high-precision timer of the STM32 controller, and the controller can accurately record the passage time of each droplet to ensure accurate measurement of the drug dripping speed; the operating temperature range of the QL2932 photoelectric sensor is -30℃ to 70℃, which adapts to the high temperature environment of the top heating part of the experimental pill machine, ensuring the stable operation of the counting sensor under harsh conditions.

[0058] The controller is connected to the steering gear, and sends a control signal to the steering gear according to the calculated drug dripping speed. The steering gear adjusts the angle according to the control signal, thereby adjusting the opening of the control valve 12 to achieve direct control of the drug dripping speed.

[0059] The PWM timer of the STM32 controller can accurately generate a pulse width signal to ensure that the servo can achieve precise angle control, thereby finely adjusting the speed of drug dripping; the high processing speed and FPU of the Cortex-M4 core of the STM32 controller support real-time execution of the PID control algorithm, which can quickly respond to changes in the drug dripping speed and ensure the stability of the drug dripping speed. Among them, the STM32 controller cooperates with the QL2932 to achieve precise control and stable measurement of the droplet speed, ensuring the reliability and efficiency of the entire system.

[0060] The high-precision timer of the STM32 controller can accurately capture the NPN signal of the counting sensor, ensure accurate recording of the drug dripping time, and meet the high requirements of the system for measuring the drug dripping speed; the Cortex-M4 core quickly processes the real-time information of the drug dripping obtained by the counting sensor, realizes the real-time calculation of the drug dripping speed, and provides accurate feedback signals for controlling the steering gear, thereby ensuring that the system is timely adjusted and accurately controlled to the drug dripping speed. The STM32 controller, with its high-performance ARM Cortex-M4 core, rich timer resources, DSP and FPU functions, provides strong support for the use of three key devices (steering gear, counting sensor and touch screen) in the drug drop counting and speed measurement system, which can not only accurately control the angle of the steering gear, display and adjust the information on the touch screen in real time, but also efficiently process the signal input of the counting sensor, ensuring the accuracy, real-time and reliability of the whole system.

[0061] The servo of this embodiment is preferably a DS3120 high-precision metal gear servo, whose parameters can meet the requirements of the control valve 12. Among them, the high torque of the DS3120 high-precision metal gear servo can support the precise control of the opening of the control valve 12 (the DS3120 high-precision metal gear servo provides a torque of up to 22kg / cm, which means that it can exert sufficient force to control the rotation of various mechanical switches, even heavier or tighter switches. This high torque ensures that the servo can smoothly and accurately control the opening and closing of the switch under different load conditions); the DS3120 high-precision metal gear servo has a fast response speed (at a voltage of 7.2V, the speed of the DS3120 high-precision metal gear servo is 0.14 seconds / 60°, which shows that the servo can complete a large angle of rotation in a very short time. This fast response is very critical for the real-time adjustment of the drug dripping speed. It can ensure that the system quickly adjusts the switch angle after detecting the deviation of the drug dripping speed and promptly restores to the pre-set drug dripping speed. The fast response speed also enables the servo to find a balance between fast adjustment and stable control to avoid overshoot or insufficient adjustment); the DS3120 high-precision metal gear servo has a small dead zone and high control precision. The DS3120 high-precision metal gear servo has a high degree of accuracy (the dead zone of the DS3120 high-precision metal gear servo is 3μs, which means that it is very sensitive to small changes in the input control signal and can accurately respond to the instructions issued by the controller; this is very important for subtle adjustments to the drug dripping speed, because even small speed changes require the servo to quickly and accurately adjust the switch angle); the DS3120 high-precision metal gear servo has a wide operating voltage range (the DS3120 high-precision metal gear servo supports an operating voltage of 4.8V to 7.2V, has strong adaptability, and can work stably under different power supply conditions. This feature makes it more reliable in complex industrial environments and ensures the continuous stability of switch control); the DS3120 high-precision metal gear servo has a high metal gear control frequency (the DS3120 high-precision metal gear servo is equipped with metal gears, which can improve the durability and accuracy of the servo, and can work for a long time under high load conditions without being easily worn. The control frequency of the metal gears is as high as 330Hz, which enables the servo to quickly receive and respond to control signals, further improving the control speed and accuracy of the system). The high torque, fast response, low dead zone and wide operating voltage range of the DS3120 high-precision metal gear servo make it very suitable for accurately controlling the rotation of mechanical switches, especially in droplet speed control systems. Through the precise PWM control of the STM32 controller, the servo can quickly and accurately adjust the switch angle in response to the real-time detected droplet speed changes, ensuring the system's fine control of speed and ensuring consistency and efficiency in the pill machine production process.

[0062] The controller is connected to the touch screen and is used to send the drug dripping speed and the angle of the servo to the touch screen. The touch screen displays the drug dripping speed and the angle of the servo in real time, helping the operator to monitor the working process of the experimental pill machine in real time and provide a reference for adjusting the opening of the control valve 12; the touch screen also displays a touch option for manually adjusting the servo angle, enabling the operator to directly control the drug dripping speed.

[0063] The touch screen of this embodiment has a rich peripheral interface (such as SPI, I2C, FSMC), supports high-speed communication between the controller and the touch screen, and ensures a smooth user operation experience; and can update the speed of drug dripping and the angle of the servo displayed on the touch screen in real time, and supports the user to manually adjust the angle of the servo through the touch screen, simplifying the operation process. The touch screen is preferably a Taojingchi T1 capacitive screen, and its parameters can meet the display parameters and control the needs of the pill machine. Among them, the Taojingchi T1 capacitive screen is 4.3 inches and has a display ratio of 16:9, which is suitable for displaying complex operation interfaces. At the same time, its operating voltage is 4.5-6.0V, which is compatible with the voltage requirements of the STM32 controller. The operating temperature range of the screen is -20°C to 70°C, which adapts to the temperature requirements of the industrial environment and ensures stable operation in the pill machine system; the Taojingchi T1 capacitive screen has 3584Bytes of running memory and a main control frequency of 64MHz, which can support efficient touch operations and interface updates. The capacitive touch type provides users with accurate touch feedback and smooth operation experience, which makes it more intuitive and convenient to adjust the angle of the servo and monitor the speed of drug dripping in real time in the counting and speed control system; the Taojingchi T1 capacitive screen is widely used in smart homes, lighting and industrial equipment, and its stability and reliability have been verified. It is also reasonable to use it in the counting and speed control system of the pill machine, and can meet the high requirements for real-time display and operation feedback.

[0064] Example 5

[0065] Based on embodiments 1-4, the working principle of the counting and speed measurement control system includes:

[0066] The PWM timer of the STM32 controller generates a pulse width signal to control the rotation angle of the DS3120 servo; the duty cycle of the PWM signal determines the specific angle of the servo, and the counting and speed control system controls the adjustment of the duty cycle of the PWM signal according to the real-time calculated drug dripping speed to adjust the servo angle, thereby adjusting the opening of the control valve 12 to control the drug dripping speed. Among them, the counting and speed control system monitors the execution results of the servo in real time, and confirms the accuracy of the angle adjustment through the feedback mechanism to ensure that the servo can accurately execute the required opening change.

[0067] The timer of the STM32 controller is used to capture the NPN signal output by the QL2932 photoelectric sensor. When the droplet passes through the detection area of ​​the QL2932 photoelectric sensor, the QL2932 photoelectric sensor outputs a low-level signal. The STM32 controller detects this change through an external interrupt or timer capture function. By recording the time difference between the two low-level signals, the time interval between the droplet passing is calculated. According to the time interval, the counting and speed control system calculates the current drug dripping speed in real time and compares it with the preset drug dripping speed. In order to eliminate possible noise influences, a filtering algorithm is used to process the detection results to ensure the stability and accuracy of the speed calculation.

[0068] The I2C interface of the STM32 controller is used to communicate with the 4.3-inch capacitive touch screen. The I2C bus is first initialized in the software, including setting parameters such as communication rate and address mode to ensure stable communication with the touch screen. The microcontroller transmits key data such as droplet speed and servo angle to the touch screen in real time through the I2C protocol. After receiving the data, the touch screen updates the display content to provide users with real-time operation feedback; the capacitive touch function of the touch screen allows users to adjust the servo angle directly through the touch screen. The microcontroller reads the touch data of the touch screen through I2C, adjusts the servo control parameters according to user input, and responds to user operations in real time.

[0069] For ease of explanation, spatial relative terms such as "upper", "lower", "left", "right" and the like are used in the embodiments to illustrate the relationship of one element or feature shown in the figure relative to another element or feature. It should be understood that, in addition to the orientation shown in the figure, the spatial terms are intended to include different orientations of the device in use or operation. For example, if the device in the figure is inverted, the element described as being "under" other elements or features will be positioned "on" other elements or features. Therefore, the exemplary term "under" can include both upper and lower orientations. The device can be positioned in other ways (rotated 90 degrees or in other orientations), and the spatial relative descriptions used here can be interpreted accordingly.

[0070] Furthermore, relational terms such as “first” and “second” and the like are merely used to distinguish one component from another having the same name, but do not necessarily require or imply any such actual relationship or order between these components.

[0071] The above is only a preferred embodiment of the present invention. It should be pointed out that, for ordinary technicians in this technical field, several improvements and modifications can be made without departing from the principle of the present invention. These improvements and modifications should also be regarded as the scope of protection of the present invention.

Claims

1. An experimental pill machine, characterized in that: It includes a drip bucket, a control unit and a coolant circulation device; The control unit is placed on the shelf, and the control unit includes a heating body thermostat, a cooling thermostat, a circulation pump control switch and a main switch; The outer side of the drip bucket is covered with a heater, the heater is electrically connected to a heater temperature controller to control the heating temperature of the heater, the bottom of the drip bucket is connected to a drip port, and the drip port is provided with a control valve for controlling the size of drug droplets; The coolant circulation device comprises a condenser, a coolant tank and a circulation pump, wherein the condenser comprises a straight condenser and a curved condenser, wherein the straight condenser is connected to the curved condenser, wherein the top opening of the straight condenser is located directly below the drip bucket, and the outlet of the curved condenser is located above the coolant tank; The coolant box comprises a box body and a refrigeration mechanism for cooling the coolant in the box body, the top of the box body is provided with a first opening and a second opening, and a mesh plate for filtering the pellets flowing out of the curved condenser tube is placed on the top of the first opening; The coolant tank is connected to the inlet of the circulation pump through an input pipeline; the circulation pump is connected to a circulation pump control switch to control the circulation pump switch, and the outlet of the circulation pump is connected to the straight condenser through an output pipeline.

2. The experimental pill machine according to claim 1, characterized in that: It also includes a bracket and a base, the bracket includes a first bracket, a second bracket and a third bracket, the first bracket, the second bracket and the third bracket are respectively fixedly mounted on the base; the shelf is fixedly mounted on the third bracket; the drip bucket is mounted on the first bracket through a first fixing clamp; the shelf is fixedly mounted on the third bracket; the straight condenser is mounted on the first bracket through a second fixing clamp, and the curved condenser is mounted on the first bracket through a third fixing clamp; the coolant tank is fixedly mounted on the second bracket through a fourth fixing clamp.

3. The experimental pill dropping machine according to claim 1, characterized in that: The lower side wall of the straight condenser is detachably connected with a glass bend tube, and the outlet of the glass bend tube is fixedly connected to the inlet of the curved condenser.

4. The experimental pill dropping machine according to claim 1, characterized in that: The outlet of the circulation pump is connected to an output pipeline, and the other end of the output pipeline is connected to a straight condenser through a glass elbow.

5. The experimental pill machine according to claim 1, characterized in that: The outer side surface of the box body is provided with a heat-insulating layer for keeping the coolant in the box body warm.

6. The experimental pill dropping machine according to claim 1, characterized in that: The refrigeration mechanism is a semiconductor refrigeration system or a compressor refrigeration system, and the semiconductor refrigeration system includes a semiconductor refrigeration temperature control probe, a semiconductor refrigeration sheet, a heat sink fin and a fan. The semiconductor refrigeration temperature control probe enters from the second opening and contacts the coolant in the box body. The semiconductor refrigeration temperature control probe is connected to the refrigeration thermostat to control the cooling temperature; the semiconductor refrigeration sheet is fixedly installed on the side wall and / or the bottom of the box body, and a mounting hole is formed in the middle position of the semiconductor refrigeration sheet. The fourth bracket passes through the mounting hole and is fixedly installed on the bottom of the box body. Multiple groups of heat sink fins are symmetrically installed on both sides of the fourth bracket, and a fan is fixedly installed in the middle position of the multiple groups of heat sink fins to cool the heat sink.

7. The experimental pill dropping machine according to claim 1, characterized in that: The circulating pump is a diaphragm pump.

8. The experimental pill dropping machine according to claim 1, characterized in that: The experimental pill machine also includes a counting and speed measurement control system, which includes a controller and a counting sensor, a servo and a touch screen electrically connected to the controller. The counting sensor is used to obtain real-time information on drug dripping at the dripping port. The controller is electrically connected to the servo to control the rotation angle of the servo, and the opening of the control valve is controlled by controlling the rotation angle of the servo.

9. The experimental pill dropping machine according to claim 8, characterized in that: The controller is an STM32 controller.

10. A method for preparing dripping pills based on the experimental dripping pill machine according to any one of claims 1 to 9, characterized in that: The following steps are involved: Step 1, using a semiconductor refrigeration temperature control probe to detect the temperature of the coolant inside the box. If the temperature of the coolant inside the box does not meet the standard, the semiconductor refrigeration chip is connected through the refrigeration thermostat, and the semiconductor refrigeration chip is used to exchange heat with the coolant inside the box. The fan is started, and the heat dissipation fins are used to dissipate heat and cool the semiconductor refrigeration chip, thereby exchanging heat and cooling the coolant inside the box to make the coolant temperature meet the standard; Step 2, turning on the circulating pump through the circulating pump control switch, and using the circulating pump to pump the coolant with the temperature reaching the standard inside the box into the straight condenser tube, so that the coolant height in the straight condenser tube and the curved condenser tube reaches a preset height; Step 3, pouring the melted medicine into the dripping funnel, setting the heating temperature of the heating body to heat the medicine in the dripping funnel, and when the heating body thermostat detects that the temperature of the medicine in the dripping funnel reaches the dripping requirement, using the control valve to control the medicine dripping port switch, so that the medicine in the dripping funnel drips into the straight condenser through the dripping port, and using the coolant in the straight condenser to quickly cool the medicine to form dripping pills; Step 4, the pellets formed in the straight condenser tube flow out to the curved condenser tube along with the coolant, and flow out to the mesh plate along the curved condenser tube, the pellets are trapped in the mesh plate, and the coolant flows into the box through the mesh plate, and steps 1-2 are repeated again to realize the recycling of the coolant; Step 5, remove the sieve plate and pour the pellets into a storage container to complete the preparation of the pellets.

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