Full-intelligent double-cavity ethylene oxide sterilization cabinet

Abstract

The invention relates to an ethylene oxide sterilization cabinet which is widely applied to the fields of medical instrument sterilization and the like, in particular to a double-cavity ethylene oxide sterilization cabinet with full-intelligent control sterilization and analysis functions. The invention provides a full-intelligent ethylene oxide sterilization cabinet, which is characterized in that: 1, the sterilization cabinet is of a double-cavity structure, and two sterilization cabinet cavities share one set of sterilization treatment system, so that the two sterilization cavities can respectively undertake a sterilization or analysis task and also can simultaneously undertake the sterilization or analysis task; 2, the sterilization cabinet is additionally provided with a circulating air preheating system and an analysis system, the preheating system is used for carrying out hot air circulating heating and humidifying treatment before sterilization so as to improve the preheating efficiency and the temperature balance effect, and meanwhile, the optimal humidifying effect can be achieved; and full-intelligent functions including dosing and analysis are realized.

Description

Technical Field

[0001] The present invention relates to an ethylene oxide sterilizer widely used in the field of medical device sterilization, in particular to a fully intelligent double-chamber ethylene oxide sterilizer with full-intelligent control sterilization and analysis functions. Background Art

[0002] Ethylene oxide is a broad-spectrum sterilant that can kill a variety of microorganisms. Moreover, it can penetrate the packaging of medical devices for sterilization and ensure the long-term sterility of sterilized items. Therefore, it is widely used for the sterilization of medical devices.

[0003] When sterilizing with ethylene oxide, a dedicated ethylene oxide sterilizer is used. The sterilizer has a large sterilization chamber with specifications ranging from 3 to 100 cubic meters, and a small one with specifications ranging from several hundred to one thousand liters. The sterilization parameters of the ethylene oxide cabinet are: the ethylene oxide sterilization concentration is about 700mg / L, the optimal sterilization temperature is about 54℃, the sterilization humidity is about 60%RH, and generally a sterilization cycle time is about 12 hours, and the complete decomposition time is about 12 hours. Medical devices sterilized with ethylene oxide will have a certain amount of ethylene oxide residue after sterilization. According to the requirements for medical devices sterilized with ethylene oxide in the national pharmacopoeia, the ethylene oxide residue must be less than 10ug / g to be safe for use. When sterilizing, the ethylene oxide sterilizer first preheats and humidifies the sterilized items to reach the effective sterilization temperature and humidity. At present, the ethylene oxide sterilizers all use the sterilizer cabinet wall heating method. The sterilized items stacked close to the cabinet wall heat up quickly, while the sterilized items far from the cabinet wall and those blocked by objects heat up slowly, which can easily cause the sterilized items to have a poor temperature balance effect. In order to ensure that all sterilized items reach the appropriate sterilization temperature, a longer temperature balance time is required; after the sterilizer is preheated, it is evacuated and the medicine is added, which not only draws out a certain amount of air, but also Gas is needed to be added in order to be able to put in an equal amount of ethylene oxide sterilization gas. At present, the dosing of ethylene oxide sterilizers, especially large-scale ethylene oxide sterilizers, is still done manually. The dosing speed and dosage are manually controlled, which not only increases labor costs but also easily causes inaccurate dosing, poor vaporization, and safety hazards. After the sterilization is completed, negative pressure analysis is used to remove the waste gas analysis, that is, a vacuum pump is used to repeatedly extract the ethylene oxide waste gas in the sterilizer for exhaust analysis. Not only is there a safety hazard, but the analysis efficiency is low, and the analysis process cannot be intelligently controlled. At present, large and medium-sized ethylene oxide sterilizers require manual dosing, so there is no ethylene oxide sterilizer that can achieve full intelligent control and efficient preheating and analysis functions. Moreover, the current ethylene oxide sterilizers have only one sterilization chamber. The sterilization chamber is occupied during sterilization and cannot be analyzed. The sterilization chamber is occupied during analysis and cannot be sterilized. Summary of the invention

[0004] In order to overcome the shortcomings of the existing ethylene oxide sterilizer.

[0005] The present invention provides a fully intelligent ethylene oxide sterilizer, which is characterized by:

[0006] 1. The sterilization cabinet of the present invention is innovatively designed into a double-chamber structure. Two sterilization cabinet chambers share a set of sterilization processing systems. In this way, the two sterilization chambers can undertake sterilization or analysis tasks separately or simultaneously. In this way, when one sterilization chamber is analyzing, the other chamber is used for sterilization as usual, which can solve the problem that the sterilization cabinet cannot sterilize during analysis, and can double the sterilization capacity when used according to the current sterilization cabinet.

[0007] 2. The sterilization cabinet of the present invention is innovatively designed with two heating systems, namely a hot air circulation heating and humidification preheating system and a cabinet wall heating and insulation system. The hot air circulation heating and humidification preheating system is used in the preheating and humidification process before sterilization in the sterilization cabinet. The use of the preheating system for hot air circulation heating and humidification can improve the preheating efficiency and temperature balance effect, while achieving the best humidification effect. The preheating and humidification process is intelligently controlled through temperature and humidity sensor sampling and computer analysis. The information sent by the temperature and humidity sensor and the detection equipment is used to analyze the preheating process intelligently. In addition to the auxiliary sterilization cabinet preheating function, the cabinet wall heating and insulation system mainly uses cabinet wall heating to maintain a constant temperature in the cabinet during the sterilization process, and can intelligently control the sterilization cabinet wall temperature through temperature and humidity sampling and analysis to ensure a constant temperature sterilization process.

[0008] 3. The sterilization cabinet of the present invention is innovatively designed with a set of automatic parsing system, which performs parsing after sterilization is completed. The parsing system uses the fan in the hot air circulation heating and humidification preheating system to perform parsing on the sterilization cabinet in a positive pressure manner (currently all ethylene oxide sterilization cabinets use a vacuum pump to perform exhaust parsing in a negative pressure manner with repeated air extraction and ventilation). At the same time, the system sets an ethylene oxide gas detection device at the exhaust port of the sterilization cabinet, and uses a computer to sample and analyze the ethylene oxide residue in the sterilization cabinet through the ethylene oxide detection device, thereby intelligently controlling the parsing process.

[0009] 4. The sterilizing cabinet of the present invention adopts a special ethylene oxide sterilizing agent automatic vaporizer. The sterilizing agent capacity of the ethylene oxide sterilizing agent automatic vaporizer is the same as the dosage of the sterilizing cabinet each time, and its heating and vaporization time is synchronized with the dosage time of the sterilizing cabinet.

[0010] The technical solution adopted by the present invention to solve its technical problem is:

[0011] Firstly, we designed and developed a fully intelligent control software. The control procedure of this software is as follows: after the sterilization cabinet has completed the sterilization preparation work, it will start (sterilization chamber 1 or 2) and then enter the fully intelligent control state, and perform the whole sterilization analysis and record the whole information. First, sterilization preheating and humidification are started. The preheating temperature set in the program is 54°C and the humidity is 60%RH. When the set temperature and humidity are reached and stabilized (the constant temperature time is set), the next step is automatically carried out; the next step is evacuation, and the vacuum pump starts working (for example, the vacuum degree is set to -40Kpa). When the set vacuum degree is reached, the vacuum pump stops, and the program enters the pressure holding stage (such as setting the pressure holding time to 10 minutes or 20 minutes). When the pressure holding is completed and the vacuum degree remains within the normal range, it means that the sterilization chamber is well sealed, and the next step of drug administration is automatically carried out (the drug administration time is set to ensure that all the drugs are vaporized and enter the sterilizer); when entering the drug administration program, the drug administration pipeline valve of the sterilizer is opened, and the heating power of the automatic drug vaporizer is turned on, and the vaporizer is heated (the vaporization temperature of ethylene oxide drugs is 10.5°C). In this way, the vaporizer in the vaporizer The ethylene oxide agent will be completely vaporized and enter the sterilizer; after the administration is completed, the sterilization program will begin (such as setting the sterilization time to 480 minutes). At this time, the sterilization constant temperature of the sterilizer (54℃±5℃) is guaranteed by controlling the heating of the cabinet wall; when the sterilization is completed, the analysis program will automatically begin. At this time, the corresponding analysis valve will open, the analysis fan will start working, and the ethylene oxide gas detector will also start working. The operation of the analysis fan will be controlled by the ethylene oxide gas detector. When ethylene oxide gas is detected, the analysis fan will start running. When the detector cannot detect ethylene oxide gas, the analysis fan will stop. When the sterilized items evaporate ethylene oxide residual gas, the ethylene oxide detector will detect it and start the analysis fan again. This cycle will be repeated until the ethylene oxide residual amount of the sterilized items reaches the qualified standard, and all the sterilization and analysis programs are completed.

[0012] With the control software, the technical solution for further innovation of hardware suitable for software control is:

[0013] 1. Design two sterilization chambers (such as a single-door refrigerator and a double-door refrigerator). These two identical sterilization chambers share a set of sterilization and analysis systems, and the solenoid valve can be used to control which sterilization chamber is connected to the sterilization system and the analysis system. The two sterilization chambers can be used separately or simultaneously. Through the control of the computer program, these two chambers can be used for sterilization at the same time, and one chamber can be sterilized while the other chamber is analyzed, without delaying each other. Because a normal sterilization cycle time is about 12 hours, and the analysis time is also about 12 hours. If there is only one sterilization chamber, it is impossible to perform sterilization again during the analysis process. The present invention has two sterilization chambers. For example, when one sterilization chamber is performing analysis work, the other chamber can perform sterilization work as usual.

[0014] 2. The preheating of the sterilizing cabinet of the present invention is based on the wall heating of the current sterilizing cabinet, and a hot air circulation heating and analysis system is additionally provided. That is, ventilation holes are opened on the top and bottom of the sterilizing cabinet cavity and connected to the circulating ventilation duct, and a valve is provided to control the opening of the duct. The ventilation duct is connected to the air inlet and outlet of the hot air heating equipment to form a closed circulating heating and humidification system. Before sterilization, the hot air circulation heating and analysis system starts to execute the preheating working procedure, the heating unit of the hot air circulation heating and analysis system works, and the circulating fan is started. At this time, hot air enters from the opening on the top of the sterilizing cabinet and is treated to uniformly heat and humidify the sterilized items. The heated air enters the air inlet of the hot air heating equipment through the duct from the front and rear air outlets opened at the bottom of the sterilizing cabinet (to facilitate uniform heating of the items), and circulates into the sterilizing cabinet to heat the sterilized items after heating. This greatly improves the preheating efficiency and the temperature balance effect. At the same time, the preheating and humidification process is intelligently controlled through sampling by temperature and humidity sensors and computer analysis. After preheating, close the ventilation duct to keep the sterilizer sealed. During the sterilization process, use cabinet wall heating to maintain a constant temperature inside the cabinet. Through temperature and humidity sampling and analysis, the temperature of the sterilizer wall is intelligently controlled to ensure a constant temperature sterilization process.

[0015] 3. After the sterilization is completed, the parsing program is entered. At this time, the parsing system starts the parsing work, because the parsing work and preheating work are done after sterilization and before sterilization respectively, and the two will not work at the same time. Therefore, the two can share the sterilizer inlet and outlet and the common circulating fan. During parsing, the circulating fan is the same as preheating. Hot air is blown into the sterilizer from the pipe above the sterilizer and discharged from the exhaust pipe below the sterilizer. Unlike the circulating air preheating, the circulating air preheating adopts a closed circulation method, while the parsing adopts a non-circulating method of open air intake and open exhaust, and is controlled by the control valve of the pipeline, that is, the control valve of the hot air circulation and heating parsing system and the air outlet pipe at the bottom of the sterilizer is closed, and the gas discharged from the sterilizer cannot be circulated into the hot air circulation and heating parsing system, but enters the parsing exhaust pipe connected to the outlet tee (the control valve of the exhaust pipe is open at this time), and the sterilization waste gas of the sterilizer is discharged through the exhaust pipe for parsing. At the same time, the air intake of the circulating heating parsing system is through the air inlet connected to the pipe tee (the control valve of the air inlet pipe is open at this time). In this way, during analysis, the sterilization cabinet of the present invention adopts a positive pressure blowing method for exhaust analysis (currently all ethylene oxide sterilization cabinets adopt a negative pressure method of a vacuum pump to repeatedly evacuate and exchange air for exhaust analysis). At the same time, an ethylene oxide gas detection device (including a sensor) is installed in the sterilization cabinet. During analysis, the ethylene oxide residual amount in the sterilization cabinet is detected and analyzed by the installed ethylene oxide gas detection device (including a sensor). When ethylene oxide gas is detected, the heating and analysis system is started for analysis to eliminate the residual ethylene oxide waste gas in the sterilization cabinet. When no ethylene oxide gas is detected, the heating and analysis system is stopped, and the ethylene oxide residue in the sterilized items is precipitated into the sterilization cabinet. The ethylene oxide gas detection device detects the ethylene oxide waste gas and starts the warm analysis system for analysis again. In this way, the analysis process can be intelligently judged and controlled by repeating the process until the ethylene oxide gas detection device (including the sensor) can no longer detect the ethylene oxide waste gas, and the analysis work is completed, thereby realizing an intelligent analysis program.

[0016] 4. The sterilizer of the present invention adopts a special ethylene oxide sterilizer automatic vaporizer. The sterilizer capacity of the designed ethylene oxide sterilizer automatic vaporizer is the same as the dosage of the sterilizer used each time. That is, the ethylene oxide sterilizer automatic vaporizer of the corresponding specification is designed according to the sterilization volume specification of the sterilizer, so that the sterilizer capacity loaded by this automatic vaporizer is exactly the sterilization dosage required by the sterilizer of the volume specification. For example, a sterilizer with a volume specification of 20 cubic meters requires 14 kilograms of ethylene oxide agent for sterilization, and its corresponding ethylene oxide sterilizer automatic vaporizer is also loaded with 14 kilograms of ethylene oxide agent. This sterilant automatic vaporizer consists of a heating belt wrapped around the outside of the medicine tank and a temperature control system. The power supply of the heating belt is intelligently controlled by the control program of the sterilizer. When in use, the outlet of the sterilizer automatic vaporizer is connected to the sterilizer dosing port pipe, and the sterilizer dosing port pipe is controlled by a control valve to control opening and closing. When the sterilizer control program is executed to dosing, the program controls the sterilizer dosing port pipe to be opened by the control valve, and at the same time controls the connection of the power supply of the heating belt of the sterilizer automatic vaporizer to start heating the sterilizer automatic vaporizer. In this way, the ethylene oxide sterilant in the vaporizer will be automatically vaporized and put into the sterilizer until the sterilizer is completely vaporized and put into the sterilizer. The dosing program ends, and the program controls to cut off the power supply of the heating belt of the automatic vaporizer and close the dosing pipe control valve to complete the dosing process, thereby realizing intelligent control of the dosing process.

[0017] The beneficial effects of the present invention are:

[0018] The innovative use of ethylene oxide sterilizer automatic vaporizer and automatic analysis system realizes fully intelligent control of the entire sterilization and analysis process, improving the quality of sterilization and analysis; and the novel design of the double-chamber structure improves the utilization efficiency of the sterilization cabinet, combined with the innovative design of hot air circulation preheating and positive pressure analysis device, improves the sterilization and analysis efficiency and enhances practicality.

[0019] The present invention is further described below in conjunction with the accompanying drawings and embodiments. BRIEF DESCRIPTION OF THE DRAWINGS

[0020] Attached Figure 1 It is a working principle diagram of the present invention.

[0021] In the attached drawings, 1 is a sterilization analysis chamber 1; 2 is a sterilization analysis chamber 2; 3 is a preheating analysis group (including a heating device and a fan); 4 is a humidifier; 5 is a vacuum pump; 6 is an automatic drug vaporizer; 7 is an ethylene oxide detector; 8 is an ethylene oxide detector; 9 is a preheating air circulation duct of the sterilization analysis chamber 1; 10 is a preheating air circulation duct of the sterilization analysis chamber 2; 11 is a analysis exhaust duct of the sterilization analysis chamber 1; 12 is a sterilization analysis chamber 2 The analytical exhaust of cavity 2; others with K prefix are control valves (including K1, k2, k3, k4, k5, k6, k7, K8, k9, k10, k11 are all pneumatic ball valves controlled by computer programs) and sensors (1-1 and 1-2 are two sets of temperature and humidity sensors for cavity 1, 1-3 is the pressure sensor for cavity 1; 2-1 and 2-2 are two sets of temperature and humidity sensors for cavity 2, 2-3 is the pressure sensor for cavity 2);. DETAILED DESCRIPTION When the sterilizing cabinet of the present invention is used for sterilization, the functions of the two sterilization chambers are the same. The chamber that is connected through the system will execute the corresponding working procedure. Take the working of chamber 1 as an example: when the sterilization chamber 1 is loaded with sterilized items and the door is sealed, the sterilization working procedure of the sterilization chamber is started. First, the preheating and humidification procedure is entered. At this time, the program controls valves k1 and k3 to open, and 3 preheating analysis groups work. The hot air circulates and heats the sterilized items in the direction shown in the figure (the cabinet wall heating is also started at the same time). If the humidity information value transmitted by sensor 1-1 is lower than the required 60%, k12 is also opened, and 4 humidifiers also start working. During the execution of this program, the temperature and humidity information transmitted by sensor 1-1 is used to automatically determine the heating and humidification status of the program. When the temperature and humidity have reached the appropriate sterilization temperature and humidity (normally 54℃±5℃ and 60%RH±10%RH), and the equilibrium time is guaranteed (such as setting the temperature equilibrium time to 60 minutes or 120 minutes), the preheating and humidification program ends, the humidifier of the 3 preheating and decomposition group (including heating equipment and fan) is turned off, and the ki, k3, and k12 control valves are closed; enter the next program - evacuation. During evacuation, the 5 vacuum pump works, and the k9 control valve is opened. When the vacuum pressure information sent by the pressure sensor of the 1-3 cavity 1 reaches the set value (for example: - 40kpa), the vacuum pump stops working, and the k9 control valve is also closed. At this time, the program enters the pressure holding state (for example, the pressure holding time is set to 10 minutes). When the pressure holding time ends, the pressure value does not exceed the value, indicating that the sterilization chamber is well sealed, and it automatically enters the next program-dosing. At this time, the power supply of the 6th agent automatic vaporizer is connected to the ethylene oxide agent for heating and vaporization, the k11 control valve is opened, and the vaporized ethylene oxide gas enters the 1st sterilization chamber. When it is ensured that all vaporization and dosing are completed (such as setting the dosing time to 20 minutes), it automatically enters the next program-sterilization. At this time, the cabinet wall is heated according to the temperature and humidity information transmitted by sensor 1-1, and the program automatic controller heats or stops to ensure the temperature value of the sterilization temperature (generally 54℃±5°). When the set sterilization time is reached (for example, the sterilization time is set to 480 minutes), the sterilization ends and enters the next program-analysis. At this time, the 3 preheating and analysis groups start to work, and the k1, k5, and k7 control valves are opened. The 3 preheating and analysis groups take in air through k7 and send air to the 1 sterilization chamber through k1, and then remove the sterilization waste in the sterilization chamber through the k5 control valve. Gas, 1 sterilization chamber and sterilized items are analyzed. At this time, 7 ethylene oxide detectors start working. When the ethylene oxide value detected by 7 ethylene oxide detectors is zero, 3 is the preheating analysis group, which temporarily stops working. At this time, the ethylene oxide residue in the sterilized items in the sterilization analysis chamber will evaporate into the room. When 7 is the ethylene oxide detector that detects the volatilized ethylene oxide, 3 preheating analysis group starts working again. This cycle repeats until the sterilized items no longer emit ethylene oxide, the surface ethylene oxide residue is qualified, and the analysis work is stopped. The entire sterilization and analysis process is completed with full intelligent control.

Claims

1. A fully intelligent ethylene oxide sterilizer, characterized by: The sterilization cabinet is innovatively designed with a dual-chamber structure, with two sterilization cabinet chambers sharing a sterilization processing system. In this way, the two sterilization chambers can undertake sterilization or analysis tasks separately or simultaneously.

2. A fully intelligent ethylene oxide sterilizer, characterized by: The sterilizer is innovatively designed with two heating systems, namely the hot air circulation heating and humidification preheating system and the cabinet wall heating and insulation system. The hot air circulation heating and humidification preheating system is used in the preheating and humidification process before sterilization in the sterilizer. Using the preheating system for hot air circulation heating and humidification can improve the preheating efficiency and temperature balance effect, while achieving the best humidification effect. The preheating and humidification process is intelligently controlled through temperature and humidity sensor sampling and computer analysis. The information sent by the temperature and humidity sensor and the detection equipment is used to analyze the intelligent control of the preheating process. In addition to the auxiliary sterilizer preheating function, the cabinet wall heating and insulation system mainly uses cabinet wall heating to keep the cabinet constant temperature during the sterilization process, and can intelligently control the sterilization cabinet wall temperature through temperature and humidity sampling and analysis to ensure the constant temperature process of sterilization.

3. A fully intelligent ethylene oxide sterilizer, characterized by: The sterilizer is innovatively designed with an automatic analysis system, which performs analysis after sterilization is completed. The system uses the fan in the hot air circulation heating and humidification preheating system to analyze the sterilizer in a positive pressure manner. At the same time, the system sets an ethylene oxide gas detection device at the exhaust port of the sterilizer, and uses a computer to sample and analyze the ethylene oxide residue in the sterilizer through the ethylene oxide detection device, and intelligently controls the analysis process.

4. A fully intelligent ethylene oxide sterilizer, characterized by: The sterilizer uses a dedicated ethylene oxide sterilant automatic vaporizer. The sterilant capacity of the ethylene oxide sterilizer automatic vaporizer is the same as the dosage of the sterilizer each time, and its heating and vaporization time is synchronized with the dosage time of the sterilizer.

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