Device and method for preparing and purifying high performance liquid chromatography (HPLC) solvent

Abstract

The invention belongs to the technical field of liquid chromatography (HPLC) solvent preparation equipment, and discloses a high performance liquid chromatography (HPLC) solvent preparation and purification device which comprises four supporting legs, and top plates are fixedly mounted at the tops of the four supporting legs. By arranging the movable block, the stirring blade bodies and the flexible spring, when the movable rod drives the three stirring blade bodies to rotate, materials in the mixing reaction box can be mixed, stirred and reacted, and when an exhaust pipe introduces gas into the movable rod and the gas cannot be exhausted, the movable rod can be driven by the exhaust pipe to rotate. When the gas in the movable rod can be exhausted, the three stirring blade bodies are reset due to the elastic force recovery effect of the flexible spring, so that the gas in the movable rod can be exhausted, and the stirring and mixing positions of the three stirring blade bodies can be changed. And the three stirring blade bodies can do lifting reciprocating motion in the stirring and mixing process.

Description

Technical Field

[0001] The invention belongs to the technical field of liquid chromatography HPLC solvent preparation equipment, and specifically relates to a high performance liquid chromatography HPLC solvent preparation and purification device and method. Background Art

[0002] High Performance Liquid Chromatography (HPLC) is an ideal analytical tool that can achieve rapid separation and determination of chemical substances with high precision and sensitivity. The normal operation of the HPLC system depends on pure solvents. Special applications require special pure solvents. HPLC is used to study the properties of separation, determination and characterization of substances, and these studies are all based on solvents.

[0003] At present, when enterprises produce and prepare HPLC solvents, they often use relevant purification devices to enable mixing reactions between various materials so that operators can obtain the required solvents. In actual use, the existing purification devices will have a stirring mechanism inside them, so as to utilize the rotation of the stirring mechanism to promote the mixing reaction between various materials and solvents. However, the stirring mechanism mainly utilizes the rotation of stirring blades. In the prior art, there are gaps between the stirring blades. In this way, when the stirring mechanism is rotating, it is easy to cause the solution in the gap to fail to be fully stirred, which will increase the mixing time between the materials and bring inconvenience to the operator's operation.

[0004] At the same time, when the operator adds some solid materials into the purification device, if the solid materials are a little damp or the inlet of the purification device is a little damp, some solid materials will be attached to the inlet. At this time, the added solid materials will not be able to enter the interior of the purification device smoothly, which not only causes a certain degree of waste of materials, but also has a certain adverse effect on the quality of the solvent generated by the mixed reaction.

[0005] Moreover, when some solid materials enter the interior of the purification device, most of the solid materials will fall vertically due to the influence of gravity, which will cause some solid materials to be unable to be effectively and evenly dispersed inside the purification device. When most of the solid materials are concentrated in one place, it will cause the subsequent solid materials to be mixed fully and evenly in a short time during the stirring and mixing process, which will extend the time for solvent preparation and is not conducive to the use of operators. Therefore, it needs to be improved. Summary of the invention

[0006] The object of the present invention is to provide a high performance liquid chromatography (HPLC) solvent preparation and purification device and method to solve the problems raised in the above background technology.

[0007] In order to achieve the above-mentioned purpose, the present invention provides the following technical scheme: a high performance liquid chromatography (HPLC) solvent preparation and purification device, comprising support legs, the number of the support legs is four, the tops of the four support legs are fixedly mounted with a top plate, the interior of the top plate is fixedly sleeved with a mixing reaction box, the top and bottom ends of the mixing reaction box respectively penetrate the top plate and extend to the top and bottom of the top plate, the top of the mixing reaction box is provided with a feed inlet, the interior of the bottom end of the mixing reaction box is movably sleeved with a movable rod, the top end of the movable rod penetrates the mixing reaction box and extends to the inside of the feed inlet, the bottom end of the movable rod penetrates the mixing reaction box and extends to the mixing reaction box A driven gear is fixedly sleeved at the bottom, and a vertical groove located inside the mixing reaction box is opened on the outer surface of the movable rod, and a movable block is movably sleeved inside the vertical groove, and the outer surface of the movable block is movably connected to the inner surface of the movable rod. There are three movable blocks, and connecting rods are fixedly sleeved between the insides of the three movable blocks. A flexible spring is fixedly connected to the bottom of the movable block, and the other end of the flexible spring is fixedly connected to the bottom of the inner cavity of the movable rod. The outer surface of the movable block is fixedly connected to a stirring blade body located outside the movable rod, and there are three stirring blade bodies, and the inner surfaces of the three stirring blade bodies are movably connected to the outer surface of the movable rod.

[0008] Preferably, a driving motor is fixedly installed on the left side of the bottom of the mixing reaction box, the other end of the output shaft of the driving motor is fixedly sleeved with a rotating shaft, the outer surface of the top end of the rotating shaft is fixedly sleeved with a driving gear, and the outer surface of the driving gear is meshedly connected with the outer surface of the driven gear.

[0009] Preferably, a mounting plate is fixedly installed on the top of the right side of the mixed reaction box, a fixing frame is fixedly installed on the right side of the top of the mixed reaction box, an air pump is fixedly installed on the top of the mounting plate, a vacuum pipe is fixedly installed on the front of the air pump, an exhaust pipe is fixedly connected to the top of the air pump, the other end of the exhaust pipe passes through the fixing frame and extends to the interior of the top end of the movable rod, and the outer surface of the bottom end of the exhaust pipe is movably connected to the inner surface of the top end of the movable rod.

[0010] Preferably, a dust-proof and breathable net is fixedly sleeved on the outer surface of the mixing reaction box and is located above the stirring blade body and below the mounting plate. The dust-proof and breathable net is distributed around the inner part of the outer surface of the mixing reaction box.

[0011] Preferably, a scraper blade located inside the feed inlet is fixedly sleeved on the outer surface of the top end of the movable rod, and the outer surface of the scraper blade is movably connected to the inner surface of the feed inlet.

[0012] Preferably, a first opening is opened on the outer surface of the bottom end of the exhaust pipe, and the first opening is evenly surrounded by the outer surface of the bottom end of the exhaust pipe.

[0013] Preferably, the outer surface of the movable rod is provided with a second opening located between the top of the stirring blade body and the bottom of the feed inlet, the second opening is located outside the first opening, and the size of the second opening is the same as that of the first opening.

[0014] Preferably, a control valve is fixedly installed at the bottom end of the left side of the mixing reaction box, and the interior of the control valve is communicated with the interior of the mixing reaction box.

[0015] Preferably, the method comprises the following steps:

[0016] First, the operator starts the drive motor. The operation of the drive motor will cause the shaft to drive the driving gear to rotate. At this time, the outer surface of the driving gear will mesh with the outer surface of the driven gear, thereby driving the movable rod to rotate as a whole. Then the operator starts the air pump. The operation of the air pump will extract external gas through the exhaust pipe and then introduce it into the interior of the movable rod through the exhaust pipe.

[0017] The operator adds the materials that need to be stirred and mixed into the mixing reaction box through the feeding port in turn, and the movable rod as a whole will drive the scraper blade to rotate inside the feeding port during the rotation process, and the outer surface of the scraper blade will scrape the inner surface of the feeding port so that the attached materials can smoothly fall into the mixing reaction box, and when the movable rod as a whole rotates, the first opening and the second opening will be constantly staggered and overlapped, and when the first opening and the second opening are staggered, the materials falling from the feeding port will fall vertically, and when the first opening and the second opening are overlapped, the gas entering the movable rod will be discharged through the first opening and the second opening in turn, and the gas discharged from the second opening will blow the materials falling from the feeding port so that the materials can be scattered to the inside of the mixing reaction box, so that the materials can be initially evenly distributed inside the mixing reaction box;

[0018] Furthermore, when the movable rod rotates, it will also drive the three stirring blade bodies to rotate, thereby stirring and mixing the materials inside the mixing reaction box. When the first port and the second port are staggered, the gas introduced into the movable rod through the exhaust pipe will push the three movable blocks to drive the connecting rod to move downward and squeeze the flexible spring. At this time, the positions of the three stirring blade bodies for stirring and mixing the materials inside the mixing reaction box will change, thereby achieving the effect of improving the stirring and mixing of the materials inside the mixing reaction box. At the same time, when the first port and the second port overlap again, the gas above the movable block will be discharged through the first port and the second port in turn. At this time, due to the elastic reset effect of the flexible spring, the three stirring blade bodies will also reset, thereby achieving the purpose of lifting and stirring the three stirring blade bodies.

[0019] The beneficial effects of the present invention are as follows:

[0020] 1. The present invention provides a movable block, a stirring blade body and a flexible spring. When the movable rod drives the three stirring blade bodies to rotate, the materials inside the mixing reaction box can be mixed and stirred. After the exhaust pipe introduces gas into the interior of the movable rod, when the gas cannot be discharged, the gas will push the three movable blocks to drive the connecting rod to move downward as a whole and squeeze the flexible spring. At this time, the stirring and mixing positions of the three stirring blade bodies will also change. When the gas inside the movable rod can be discharged, the three stirring blade bodies will be reset due to the elastic recovery effect of the flexible spring, so that the three stirring blade bodies can be realized to perform a lifting and reciprocating motion during the stirring and mixing process, and then the gaps between the three stirring blade bodies can be effectively stirred and mixed, thereby improving the stirring and mixing reaction effect between the materials.

[0021] 2. The present invention sets a feed port and scrapers. When the movable rod rotates as a whole, it will also drive the three scrapers to rotate. At this time, the three scrapers will scrape the materials attached to the inside of the feed port, so that the materials inside the feed port can smoothly fall into the inside of the mixing reaction box. At this time, the utilization efficiency of the materials will be effectively improved, and at the same time, it will ensure that the solvent prepared subsequently has a good quality standard, which is convenient for the operator's operation.

[0022] 3. The present invention sets a first opening and a second opening. When the movable rod as a whole rotates, it will also drive the second opening to rotate. When the positions of the first opening and the second opening are staggered, the gas introduced into the movable rod by the exhaust pipe will push the three movable blocks to drive the connecting rod to move downward, and no gas is discharged. At this time, the solid material falling from the feed port will fall vertically, and when the first opening and the second opening coincide with each other, the gas entering the movable rod will be discharged through the first opening and the second opening in turn, and then the falling solid material can be blown away, so that the solid material can be evenly distributed inside the mixing reaction box, so as to increase the time for subsequent stirring and mixing reactions between materials. BRIEF DESCRIPTION OF THE DRAWINGS

[0023] Figure 1 It is a structural schematic diagram of the present invention;

[0024] Figure 2 It is a bottom view structural schematic diagram of the present invention;

[0025] Figure 3 It is a schematic cross-sectional structural diagram of the front side of the present invention;

[0026] Figure 4 It is a schematic cross-sectional structural diagram of the side of the present invention;

[0027] Figure 5 It is a schematic diagram of the separation structure of the movable rod of the present invention;

[0028] Figure 6 It is a schematic cross-sectional structural diagram of the top of the movable rod of the present invention;

[0029] Figure 7 It is a schematic diagram of the cross-sectional structure of the top of the first opening and the second opening of the present invention;

[0030] Figure 8 for Figure 3 Schematic diagram of the local enlarged structure at point A in the middle.

[0031] In the figure: 1. supporting leg; 2. top plate; 3. mixing reaction box; 4. movable rod; 5. driven gear; 6. driving motor; 7. rotating shaft; 8. driving gear; 9. vertical slot; 10. movable block; 11. connecting rod; 12. stirring blade body; 13. flexible spring; 14. air pump; 15. suction pipe; 16. exhaust pipe; 17. feeding port; 18. first opening; 19. second opening; 20. mounting plate; 21. scraper; 22. dust-proof and breathable net; 23. control valve; 24. fixing frame. DETAILED DESCRIPTION

[0032] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0033] like Figures 1 to 8As shown, in an embodiment of the present invention, a high performance liquid chromatography HPLC solvent preparation and purification device comprises support legs 1, the number of support legs 1 is four, a top plate 2 is fixedly installed on the top of each of the four support legs 1, a mixing reaction box 3 is fixedly sleeved inside the top plate 2, the top and bottom ends of the mixing reaction box 3 respectively penetrate the top plate 2 and extend to the top and bottom of the top plate 2, a feed inlet 17 is provided on the top of the mixing reaction box 3, a movable rod 4 is movably sleeved inside the bottom end of the mixing reaction box 3, the top end of the movable rod 4 penetrates the mixing reaction box 3 and extends to the inside of the feed inlet 17, the bottom end of the movable rod 4 penetrates the mixing reaction box 3 and extends to the bottom of the mixing reaction box 3 and is fixedly sleeved with The movable gear 5 and the movable rod 4 have a vertical groove 9 on their outer surfaces which is located inside the mixing reaction box 3. A movable block 10 is movably sleeved inside the vertical groove 9. The outer surface of the movable block 10 is movably connected to the inner surface of the movable rod 4. There are three movable blocks 10. A connecting rod 11 is fixedly sleeved between the insides of the three movable blocks 10. A flexible spring 13 is fixedly connected to the bottom of the movable block 10. The other end of the flexible spring 13 is fixedly connected to the bottom of the inner cavity of the movable rod 4. The outer surface of the movable block 10 is fixedly connected to a stirring blade body 12 located outside the movable rod 4. There are three stirring blade bodies 12. The inner surfaces of the three stirring blade bodies 12 are movably connected to the outer surface of the movable rod 4.

[0034] When gas enters the interior of the movable rod 4, the air pressure will push the three movable blocks 10 to drive the connecting rod 11 to move downward and squeeze the flexible spring 13. At this time, the four stirring blade bodies 12 will also be driven by the three movable blocks 10 to move, thereby changing the stirring positions of the three stirring blade bodies 12 in the initial state, so that the movable rod 4 drives the three stirring blade bodies 12 to move up and down during the stirring process. This will effectively improve the stirring and mixing effect of the materials inside the mixing reaction box 3 and increase the chemical reaction rate of the materials inside it.

[0035] Among them, a driving motor 6 is fixedly installed on the left side of the bottom of the mixing reaction box 3, and the other end of the output shaft of the driving motor 6 is fixedly sleeved with a rotating shaft 7, and the outer surface of the top of the rotating shaft 7 is fixedly sleeved with a driving gear 8, and the outer surface of the driving gear 8 is meshed and connected with the outer surface of the driven gear 5.

[0036] Therefore, when the driving motor 6 is running, the rotating shaft 7 will drive the driving gear 8 to rotate, and through the engagement between the outer surface of the driving gear 8 and the outer surface of the driven gear 5, the driven gear 5, the movable rod 4 and the stirring blade body 12 can be driven to rotate as a whole, so as to meet the stirring and mixing effect of the three stirring blade bodies 12 on the materials inside the mixing reaction box 3.

[0037] Among them, a mounting plate 20 is fixedly installed on the top of the right side of the mixing reaction box 3, a fixing frame 24 is fixedly installed on the right side of the top of the mixing reaction box 3, an air pump 14 is fixedly installed on the top of the mounting plate 20, a vacuum pipe 15 is fixedly installed on the front of the air pump 14, and an exhaust pipe 16 is fixedly connected to the top of the air pump 14. The other end of the exhaust pipe 16 passes through the fixing frame 24 and extends to the inside of the top end of the movable rod 4. The outer surface of the bottom end of the exhaust pipe 16 is movably connected to the inner surface of the top end of the movable rod 4.

[0038] When the air pump 14 is running, it will draw external gas through the exhaust pipe 15 and then introduce it into the interior of the movable rod 4 through the exhaust pipe 16.

[0039] The outer surface of the mixing reaction box 3 is fixedly sleeved with a dustproof and breathable net 22 located above the stirring blade body 12 and below the mounting plate 20 . The dustproof and breathable net 22 surrounds and is distributed inside the outer surface of the mixing reaction box 3 .

[0040] Due to the design of the dust-proof and breathable net 22, the effect of exhausting the gas inside the mixing reaction box 3 can be met, and at the same time, the materials added inside the mixing reaction box 3 can be prevented from escaping to the outside of the mixing reaction box 3, and the materials added inside the mixing reaction box 3 need to be located below the dust-proof and breathable net 22.

[0041] The outer surface of the top end of the movable rod 4 is fixedly sleeved with a scraper blade 21 located inside the feed inlet 17 , and the outer surface of the scraper blade 21 is movably connected to the inner surface of the feed inlet 17 .

[0042] When the movable rod 4 is rotating, it will not only drive the three stirring blade bodies 12 to rotate, but also drive the scraper blade 21 to rotate. At this time, the outer surface of the scraper blade 21 will scrape the inside of the feed port 17, so that the material attached to the inner surface of the feed port 17 can fall smoothly into the mixing reaction box 3, avoiding material waste.

[0043] A first opening 18 is formed on the outer surface of the bottom end of the exhaust pipe 16 , and the first opening 18 evenly surrounds the outer surface of the bottom end of the exhaust pipe 16 .

[0044] Due to the surrounding design of the first opening 18 , the airflow between the movable rod 4 and the inside of the exhaust pipe 16 can be discharged through the first opening 18 .

[0045] The outer surface of the movable rod 4 is provided with a second opening 19 located between the top of the stirring blade body 12 and the bottom of the feed inlet 17 . The second opening 19 is located outside the first opening 18 , and the size of the second opening 19 is the same as that of the first opening 18 .

[0046] When the movable rod 4 is rotating as a whole, it will also drive the second port 19 to rotate. When the position of the second port 19 coincides with the position of the first port 18, the gas discharged from the exhaust pipe 16 will be ejected through the first port 18 and the second port 19 in turn, and then the material falling from the feed port 17 can be blown away so that it can be distributed at the bottom of the inner cavity of the mixing reaction box 3. When the second port 19 is staggered with the first port 18, the airflow will not be able to be discharged. At this time, when the material inside the feed port 17 falls, it will fall vertically due to gravity. By combining the blowing of the material and the vertical falling, it is ensured that the material can be evenly dispersed inside the mixing reaction box 3, so that the subsequent three stirring blade bodies 12 can fully and evenly stir the material inside the mixing reaction box 3, and the mixing reaction time between the materials is greatly reduced.

[0047] A control valve 23 is fixedly installed at the bottom end of the left side of the mixing reaction box 3 , and the interior of the control valve 23 is communicated with the interior of the mixing reaction box 3 .

[0048] When the control valve 23 is opened, the material inside the mixing reaction box 3 can be discharged from the control valve 23 .

[0049] The steps include:

[0050] First, the operator starts the driving motor 6. The operation of the driving motor 6 will cause the rotating shaft 7 to drive the driving gear 8 to rotate. At this time, the outer surface of the driving gear 8 will mesh with the outer surface of the driven gear 5, thereby driving the movable rod 4 to rotate as a whole. Then the operator starts the air pump 14. The operation of the air pump 14 will extract external gas through the exhaust pipe 15, and then introduce it into the interior of the movable rod 4 through the exhaust pipe 16.

[0051] The operator adds the materials to be stirred and mixed into the mixing reaction box 3 through the feed inlet 17 in sequence, and the movable rod 4 as a whole will drive the scraper 21 to rotate inside the feed inlet 17 during the rotation process. At this time, the outer surface of the scraper 21 will scrape the inner surface of the feed inlet 17, so that the attached materials can smoothly fall into the mixing reaction box 3, and when the movable rod 4 as a whole rotates, the first opening 18 and the second opening 19 will be constantly staggered and overlapped. When the first opening 18 and the second opening 19 are staggered, the materials falling from the inside of the feed inlet 17 will fall vertically, and when the first opening 18 and the second opening 19 overlap, the gas entering the movable rod 4 will be discharged through the first opening 18 and the second opening 19 in sequence. At this time, the gas discharged from the second opening 19 will blow the materials falling from the feed inlet 17, so that the materials can be scattered to the inside of the mixing reaction box 3, so that the materials can be initially evenly distributed inside the mixing reaction box 3;

[0052] Furthermore, when the movable rod 4 rotates, it will also drive the three stirring blade bodies 12 to rotate, so that the materials inside the mixing reaction box 3 can be stirred and mixed. When the first opening 18 and the second opening 19 are staggered, the gas introduced into the movable rod 4 by the exhaust pipe 16 will push the three movable blocks 10 to drive the connecting rod 11 to move downward and squeeze the flexible spring 13. At this time, the positions of the three stirring blade bodies 12 for stirring and mixing the materials inside the mixing reaction box 3 will change, thereby achieving the effect of improving the stirring and mixing of the materials inside the mixing reaction box 3. At the same time, when the first opening 18 and the second opening 19 overlap again, the gas above the movable block 10 will be discharged through the first opening 18 and the second opening 19 in turn. At this time, due to the elastic reset effect of the flexible spring 13, the three stirring blade bodies 12 will also reset, thereby achieving the purpose of lifting and lowering the three stirring blade bodies 12.

[0053] It should be noted that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device.

[0054] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A high performance liquid chromatography (HPLC) solvent preparation and purification device, comprising a support leg (1), characterized in that: The number of the supporting legs (1) is four, and a top plate (2) is fixedly installed on the top of each of the four supporting legs (1). A mixing reaction box (3) is fixedly sleeved inside the top plate (2). The top and bottom ends of the mixing reaction box (3) respectively penetrate the top plate (2) and extend to the top and bottom of the top plate (2). A feed inlet (17) is provided on the top of the mixing reaction box (3). A movable rod (4) is movably sleeved inside the bottom end of the mixing reaction box (3). The top end of the movable rod (4) penetrates the mixing reaction box (3) and extends to the inside of the feed inlet (17). The bottom end of the movable rod (4) penetrates the mixing reaction box (3) and extends to the bottom of the mixing reaction box (3) and is fixedly sleeved with a driven gear (5). The outer surface of the movable rod (4) is provided with a gear located in the mixing reaction box. A vertical groove (9) is formed inside a reaction box (3), wherein a movable block (10) is movably sleeved inside the vertical groove (9), and the outer surface of the movable block (10) is movably connected to the inner surface of the movable rod (4). There are three movable blocks (10), and a connecting rod (11) is fixedly sleeved between the insides of the three movable blocks (10). A flexible spring (13) is fixedly connected to the bottom of the movable block (10), and the other end of the flexible spring (13) is fixedly connected to the bottom of the inner cavity of the movable rod (4). The outer surface of the movable block (10) is fixedly connected to a stirring blade body (12) located outside the movable rod (4). There are three stirring blade bodies (12), and the inner surfaces of the three stirring blade bodies (12) are movably connected to the outer surface of the movable rod (4).

2. A high performance liquid chromatography HPLC solvent preparation and purification device according to claim 1, characterized in that: A driving motor (6) is fixedly mounted on the left side of the bottom of the mixing reaction box (3); a rotating shaft (7) is fixedly sleeved on the other end of the output shaft of the driving motor (6); a driving gear (8) is fixedly sleeved on the outer surface of the top end of the rotating shaft (7); and the outer surface of the driving gear (8) is meshingly connected with the outer surface of the driven gear (5).

3. A high performance liquid chromatography HPLC solvent preparation and purification device according to claim 1, characterized in that: A mounting plate (20) is fixedly installed on the top of the right side of the mixing reaction box (3), a fixing frame (24) is fixedly installed on the right side of the top of the mixing reaction box (3), an air pump (14) is fixedly installed on the top of the mounting plate (20), a suction pipe (15) is fixedly installed on the front of the air pump (14), an exhaust pipe (16) is fixedly connected to the top of the air pump (14), the other end of the exhaust pipe (16) passes through the fixing frame (24) and extends to the inside of the top of the movable rod (4), and the outer surface of the bottom end of the exhaust pipe (16) is movably connected to the inner surface of the top of the movable rod (4).

4. A high performance liquid chromatography HPLC solvent preparation and purification device according to claim 1, characterized in that: The outer surface of the mixing reaction box (3) is fixedly sleeved with a dustproof and breathable net (22) located above the stirring blade body (12) and below the mounting plate (20); the dustproof and breathable net (22) is distributed around the inside of the outer surface of the mixing reaction box (3).

5. A high performance liquid chromatography HPLC solvent preparation and purification device according to claim 1, characterized in that: A scraper blade (21) located inside the feed opening (17) is fixedly sleeved on the outer surface of the top end of the movable rod (4), and the outer surface of the scraper blade (21) is movably connected to the inner surface of the feed opening (17).

6. A high performance liquid chromatography HPLC solvent preparation and purification device according to claim 3, characterized in that: The outer surface of the bottom end of the exhaust pipe (16) is provided with a first opening (18), and the first opening (18) evenly surrounds the outer surface of the bottom end of the exhaust pipe (16).

7. A high performance liquid chromatography HPLC solvent preparation and purification device according to claim 1, characterized in that: The outer surface of the movable rod (4) is provided with a second opening (19) located between the top of the stirring blade body (12) and the bottom of the feed inlet (17); the second opening (19) is located outside the first opening (18); and the size of the second opening (19) is the same as that of the first opening (18).

8. The high performance liquid chromatography (HPLC) solvent preparation and purification device according to claim 1, characterized in that: A control valve (23) is fixedly mounted on the bottom end of the left side of the mixing reaction box (3), and the interior of the control valve (23) is communicated with the interior of the mixing reaction box (3).

9. A method for preparing a solvent purification device for high performance liquid chromatography (HPLC) according to any one of claims 1 to 8, characterized in that: The following steps are involved: First, the operator starts the driving motor (6). The operation of the driving motor (6) causes the rotating shaft (7) to drive the driving gear (8) to rotate. At this time, the outer surface of the driving gear (8) will mesh with the outer surface of the driven gear (5), thereby driving the movable rod (4) to rotate as a whole. Then, the operator starts the air pump (14). The operation of the air pump (14) will extract external gas through the exhaust pipe (15) and then introduce it into the interior of the movable rod (4) through the exhaust pipe (16); The operator adds the materials to be stirred and mixed into the mixing reaction box (3) through the feed inlet (17) in sequence, and the movable rod (4) as a whole will drive the scraper (21) to rotate inside the feed inlet (17). At this time, the outer surface of the scraper (21) will scrape the inner surface of the feed inlet (17) so that the materials attached to it can fall smoothly into the mixing reaction box (3). In addition, when the movable rod (4) as a whole is rotating, the first opening (18) and the second opening (19) will be continuously staggered and overlapped. When the first opening (18) and the second opening (19) are rotated, the first opening (18) and the second opening (19) will be rotated. When the first opening (18) and the second opening (19) are staggered, the material falling from the inside of the feed port (17) will fall vertically, and when the first opening (18) and the second opening (19) overlap, the gas entering the inside of the movable rod (4) will be discharged through the first opening (18) and the second opening (19) in sequence, and the gas discharged from the second opening (19) will blow the material falling from the feed port (17) so that the material can be scattered into the inside of the mixing reaction box (3), so that the material can be initially evenly distributed inside the mixing reaction box (3); Furthermore, when the movable rod (4) rotates, it will also drive the three stirring blade bodies (12) to rotate, thereby stirring and mixing the materials inside the mixing reaction box (3). When the first opening (18) and the second opening (19) are staggered, the gas introduced into the movable rod (4) through the exhaust pipe (16) will push the three movable blocks (10) to drive the connecting rod (11) to move downward and squeeze the flexible spring (13). At this time, the positions of the three stirring blade bodies (12) for stirring and mixing the materials inside the mixing reaction box (3) will change, thereby achieving an improved effect of stirring and mixing the materials inside the mixing reaction box (3). At the same time, when the first opening (18) and the second opening (19) overlap again, the gas above the movable block (10) will be discharged through the first opening (18) and the second opening (19) in sequence. At this time, due to the elastic reset effect of the flexible spring (13), the three stirring blade bodies (12) will also reset, thereby achieving the purpose of lifting and stirring the three stirring blade bodies (12).

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