Nucleic acid extraction kit

Abstract

The invention relates to the technical field of nucleic acid extraction, in particular to a nucleic acid extraction kit, which comprises a protective box, a sliding rail arranged in the protective box and a mounting box slidably mounted on the sliding rail, and is characterized in that a supporting device is arranged on the mounting box and is used for supporting a reagent strip; one or more first damping rods are arranged on the inner side wall of the protection box, first damping springs are arranged on the first damping rods, when transverse vibration occurs, the damping effect can be better achieved under the action of the first damping springs and tension springs, meanwhile, the speed reduction and energy absorption effects of the first damping rods are matched, and the damping effect can be better achieved. And when longitudinal vibration occurs, a second damping rod and a second damping spring are matched with each other, longitudinal vibration energy can be absorbed, and the longitudinal buffering effect is achieved.

Description

Technical Field

[0001] The present invention relates to the technical field of nucleic acid extraction, and in particular to a nucleic acid extraction kit. Background Art

[0002] The magnetic bead-based nucleic acid extraction kit is a high-tech product that integrates biological science and nanomaterial science. It is a major breakthrough in my country's nucleic acid extraction and purification technology. First, the nucleic acid must be extracted into the kit, and the kit needs to be stored in a protective box to prevent damage and leakage of the kit due to collision during movement. Traditional protective boxes are very troublesome when storing and taking out the kit, requiring staff to be more careful.

[0003] At present, a Chinese patent with application number 2021213502529 discloses a nucleic acid extraction kit, including the above-mentioned technical solution, which has some problems when used. On the one hand, the buffering effect is very limited only by the spring. On the other hand, the setting of the handle, rotating disk and other components will take up a large storage space, which is not conducive to batch transportation. For this reason, the above-mentioned technical solution is improved, and a nucleic acid extraction kit with a small volume and efficient buffering is proposed. Summary of the invention

[0004] The purpose of the present invention is to provide a nucleic acid extraction kit to solve the problem of inconvenience in sample retention mentioned in the background technology. The specific technical solution is as follows:

[0005] To achieve the above-mentioned purpose and other related purposes, the present invention provides a nucleic acid extraction kit, including a protective box, a slide rail is arranged in the protective box, and an installation box is slidably installed on the slide rail. It is characterized in that a supporting device is arranged on the installation box, and the supporting device is used to support a reagent strip. One or more first damping rods are arranged on the inner side wall of the protective box, and a first shock-absorbing spring is arranged on the first damping rod. The end of the first damping rod is in contact with the rear surface of the installation box, and the installation box and the protective box are detachably connected by a connecting piece, and the connecting piece is connected to the protective box by a tension spring.

[0006] Preferably, the supporting device includes a second damping rod, a second shock-absorbing spring, a boss, an annular groove and a rotating mechanism, the end of the second damping rod passes through the top of the installation box and extends to the inside of the installation box, and is rotatably installed at the bottom of the installation box, the upper end of the second damping rod is provided with a boss, the second damping rod is provided with a second shock-absorbing spring, one end of the second shock-absorbing spring is fixedly connected to the second damping rod, and the other end is fixedly connected to the installation box, the second damping rod is provided with an annular groove, and the reagent strip is provided with a convex ring corresponding to the annular groove, the annular groove is provided with a notch, the notch is used for the convex ring to disengage from the annular groove, and the rotating mechanism is arranged inside the installation box.

[0007] Preferably, the rotating mechanism includes a ruler bar, a limit block, a button, a connecting rod and a gear, the ruler bar is slidably arranged on the limit block, the limit block is arranged at the bottom of the installation box, one end of the ruler bar is hinged with a connecting rod, the end of the connecting rod is hinged to the button, the upper end of the button passes through the top of the installation box and extends to the outside of the installation box, the gear is installed on the second damping rod and meshes with the ruler bar for transmission.

[0008] Preferably, the connecting member includes a groove plate, a sliding rod, a connecting plate and an elastic rod, one side of the groove plate is fixedly connected to the connecting plate, the connecting plate is connected to the protective box through a tension spring, two sliding rods are slidably arranged on the connecting plate, the sliding rod is fixedly connected to the protective box, the elastic rod is an L-shaped structure, the elastic rod is fixedly connected to the mounting box, a notch, a guide groove, a V-groove and a disengagement groove are provided on the groove plate, the notch is connected to the guide groove, the guide groove is connected to one end of the V-groove, the guide groove is arranged obliquely, the other end of the V-groove is connected to the disengagement groove, the disengagement groove is connected to the guide groove, the disengagement groove is connected to the guide groove, and the depth of the disengagement groove is less than the depth of the guide groove.

[0009] Preferably, a box cover is rotatably provided on the protective box.

[0010] Preferably, the groove plate is made of Teflon plastic.

[0011] Preferably, the elastic rod is made of spring steel.

[0012] Beneficial effects of the present invention:

[0013] 1. By pressing the installation box backward, the first shock-absorbing spring is compressed, and the installation box is connected to the protective box through a connecting piece. After loosening the installation box, the first shock-absorbing spring pushes the installation box, and the tension spring is stretched until a balance is reached between the tension spring and the first shock-absorbing spring. When encountering lateral shocks, under the action of the first shock-absorbing spring and the tension spring, it can better play a shock-absorbing role. At the same time, with the deceleration and energy absorption of the first damping rod, the buffering effect can be further improved, and the reagent strip can be better protected. When longitudinal shocks occur, the second damping rod and the second shock-absorbing spring cooperate with each other to absorb longitudinal vibration energy and play a longitudinal buffering role.

[0014] 2. By setting the connecting piece, when the installation box is pressed backward and released, the first shock-absorbing spring pushes the installation box forward, and the elastic rod enters the V-shaped groove under the action of its own elasticity and is fixed in the middle of the V-shaped groove. The installation box is installed in the protective box and pressed backward again. The elastic rod disengages from the V-shaped groove and enters the disengagement groove under its own elasticity, so that the installation box can be pushed backward once to be fixed and pushed again to be released. It is more convenient to use and can reduce the occupied volume. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0016] Figure 1 It is a schematic diagram of the overall structure of a nucleic acid extraction kit according to the present invention;

[0017] Figure 2 It is a schematic diagram of the internal structure of a nucleic acid extraction kit according to the present invention;

[0018] Figure 3 yes Figure 2 Schematic diagram of the structure from another perspective;

[0019] Figure 4 It is a schematic diagram of the structure of the connecting parts;

[0020] Figure 5 It is a partial structural schematic diagram of the supporting device. DETAILED DESCRIPTION

[0021] The following is a further detailed description of a nucleic acid extraction kit proposed by the present invention in conjunction with the accompanying drawings and specific embodiments. According to the following description, the advantages and features of the present invention will become clearer. It should be noted that the accompanying drawings are all in a very simplified form and are not in precise proportions, and are only used to conveniently and clearly assist in explaining the purpose of the embodiments of the present invention.

[0022] In the description of the present invention, the terms "first" and "second" are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of the features. In the description of the present invention, the meaning of "plurality" is at least two, such as two, three, etc., unless otherwise clearly and specifically defined.

[0023] It should be noted that the illustrations provided in the following embodiments are only used to illustrate the basic concept of the present invention in a schematic manner, and thus the illustrations only show components related to the present invention rather than being drawn according to the number, shape and size of components in actual implementation. In actual implementation, the form, quantity and proportion of each component may be changed arbitrarily, and the component layout may also be more complicated.

[0024] To this end, the present invention provides a nucleic acid extraction kit, such as Figure 1-5 As shown, it includes a protective box 100, a slide rail 110 is arranged inside the protective box 100, an installation box 200 is slidably installed on the slide rail 110, a supporting device 300 is arranged on the installation box 200, and the supporting device 300 is used to support the reagent strip 400, one or more first damping rods 500 are arranged on the inner wall of the protective box 100, a first shock-absorbing spring 600 is arranged on the first damping rod 500, and the end of the first damping rod 500 contacts the rear surface of the installation box 200, and the installation box 200 and the protective box 100 are detachably connected through a connecting piece 700, and the connecting piece 700 is connected to the protective box 100 through a tension spring 800.

[0025] When in use, the installation box 200 is pressed backwards, the first shock-absorbing spring 600 is compressed, and the installation box 200 is connected to the protective box 100 through the connecting piece 700. After the installation box 200 is released, the first shock-absorbing spring 600 pushes the installation box 200, and the tension spring 800 is stretched until a balance is reached between the tension spring 800 and the first shock-absorbing spring 600. When encountering lateral shocks, under the action of the first shock-absorbing spring 600 and the tension spring 800, it can better play a shock-absorbing role. At the same time, with the deceleration and energy absorption of the first damping rod 500, it can further improve the buffering effect and better protect the reagent strip 400.

[0026] In order to improve the protection capability and increase the longitudinal buffering capability of the reagent strip 400, the supporting device 300 further comprises a second damping rod 310, a second shock absorbing spring 320, a boss 330, an annular slot 340 and a rotating mechanism 350. The end of the second damping rod 310 extends through the top of the installation box 200 to the inside of the installation box 200 and is rotatably mounted on the bottom of the installation box 200. The upper end of the second damping rod 310 is provided with a boss 330. The second damping rod 310 is provided with a second shock absorbing spring 320. One end of the second shock absorbing spring 320 is provided with a boss 330. One end is fixedly connected to the second damping rod 310, and the other end is fixedly connected to the installation box 200. The second damping rod 310 is provided with an annular groove 340, and the reagent strip 400 is provided with a convex ring 360 corresponding to the annular groove 340. The annular groove 340 is provided with a notch 370, and the notch 370 is used for the convex ring 360 to be separated from the annular groove 340. The rotating mechanism 350 is arranged inside the installation box 200, and is used to control the rotation of the second damping rod 310 so that the notch 370 rotates to a position corresponding to the convex ring 360.

[0027] When in use, the reagent strip 400 is inserted between the four supporting devices 300, and the four supporting devices 300 jointly fix one reagent strip 400, and the reagent strip 400 is pressed downward so that the convex ring 360 on the reagent strip 400 is stuck in the annular groove 340. After the reagent strip 400 is released, the reagent strip 400 is supported by the second damping rod 310 under the action of the second shock-absorbing spring 320, and is fixed by the annular groove 340 and the boss 330. When vibration occurs, the second damping rod 310 and the second shock-absorbing spring 320 cooperate with each other to absorb longitudinal vibration energy and play a buffering role. When the reagent strip 400 needs to be taken out, it is only necessary to control the rotating mechanism 350 to rotate the second damping rod 310 and rotate the notch 370 to the position of the convex ring 360. At this time, the annular groove 340 releases the limit on the convex ring 360, and the reagent strip 400 can be directly taken out. After taking it out, the second damping rod 310 is reset under the action of the second shock-absorbing spring 320.

[0028] For the convenience of operation, further, the rotating mechanism 350 includes a ruler bar 351, a limit block 352, a button 353, a connecting rod 354 and a gear 355. The ruler bar 351 is slidably arranged on the limit block 352, and the limit block 352 is arranged at the bottom of the installation box 200. One end of the ruler bar 351 is hinged with a connecting rod 354, and the end of the connecting rod 354 is hinged with a button 353. The upper end of the button 353 passes through the top of the installation box 200 and extends to the outside of the installation box 200. The gear 355 is installed on the second damping rod 3 10, and meshes with the ruler bar 351 for transmission. By pressing the button 353, the button 353 moves downward, and the button 353 pushes the ruler bar 351 to slide in the limit block 352 through the connecting rod 354. The ruler bar 351 drives the gear 355 to rotate together with the second damping rod 310, thereby rotating the notch 370 to the position of the convex ring 360. If the second shock-absorbing spring 320 cannot accurately reset the second damping rod 310, a torsion spring can be added between the second damping rod 310 and the mounting box 200 to allow the second damping rod 310 to be reset more accurately.

[0029] In order to facilitate the connection and disassembly between the installation box 200 and the protective box 100, the connecting member 700 further includes a groove plate 710, a slide bar 720, a connecting plate 730 and an elastic rod 740. One side of the groove plate 710 is fixedly connected to the connecting plate 730. The connecting plate 730 is connected to the protective box 100 through a tension spring 800. Two slide bars 720 are slidably arranged on the connecting plate 730. The slide bar 720 is fixedly connected to the protective box 100. The elastic rod 740 is an L-shaped structure. The elastic rod 740 is connected to the installation box 200. The box 200 is fixedly connected, and the groove plate 710 is provided with a notch 711, a guide groove 712, a V-shaped groove 713 and a disengagement groove 714, the notch 711 is connected with the guide groove 712, the guide groove 712 is connected with one end of the V-shaped groove 713, the guide groove 712 is arranged obliquely, the other end of the V-shaped groove 713 is connected with the disengagement groove 714, the disengagement groove 714 is connected with the guide groove 712, the disengagement groove 714 is connected with the guide groove 712, and the depth of the disengagement groove 714 is less than the depth of the guide groove 712.

[0030] When the installation box 200 is pressed backward, the elastic rod 740 is inserted from the notch 711 and slidably connected with the bottom of the notch 711. The elastic rod 740 continues to be inserted. Since the depth of the escape groove 714 is less than the depth of the guide groove 712, a step is generated, so that the end of the elastic rod 740 can only slide into the guide groove 712. At this time, the elastic rod 740 is compressed. After the elastic rod 740 reaches the end of the guide groove 712, the installation box 200 is released. At this time, the first shock absorbing spring 600 pushes the installation box 200 forward, and the elastic rod 740 enters the V-groove 713 under the action of its own elasticity and is fixed in the middle of the V-groove 713, thereby installing the installation box 200 into the protective box 100. Pressing backward again, the elastic rod 740, under its own elasticity, disengages from the V-groove 713 and enters the disengagement groove 714. At this time, after releasing the installation box 200, the installation box 200 is pushed forward under the push of the first shock-absorbing spring 600, so that the installation box 200 is pushed backward once to fix it, and pushed again to release it. It is more convenient to use and can reduce the occupied volume.

[0031] Furthermore, a box cover 120 is rotatably provided on the protection box 100 .

[0032] Furthermore, the groove plate 710 is made of Teflon plastic.

[0033] Furthermore, the elastic rod 740 is made of spring steel.

[0034] Finally, it should be noted that the above embodiments are only used to illustrate the technical solution of the present invention rather than to limit it. Although the present invention has been described in detail with reference to the preferred embodiments, those skilled in the art should understand that the technical solution of the present invention can be modified or replaced by equivalents without departing from the spirit and scope of the technical solution of the present invention.

Claims

1. A nucleic acid extraction kit, comprising a protective box, wherein a slide rail is provided in the protective box, and the installation box is slidably installed on the slide rail, characterized in that: The installation box is provided with a supporting device, which is used to support the reagent strip. One or more first damping rods are provided on the inner wall of the protective box. The first damping rod is provided with a first shock-absorbing spring. The end of the first damping rod is in contact with the rear surface of the installation box. The installation box and the protective box are detachably connected via a connecting piece, and the connecting piece is connected to the protective box via a tension spring.

2. A nucleic acid extraction kit according to claim 1, characterized in that: The supporting device includes a second damping rod, a second shock-absorbing spring, a boss, an annular groove and a rotating mechanism. The end of the second damping rod passes through the top of the installation box and extends to the inside of the installation box, and is rotatably installed at the bottom of the installation box. The upper end of the second damping rod is provided with a boss. The second damping rod is provided with a second shock-absorbing spring. One end of the second shock-absorbing spring is fixedly connected to the second damping rod, and the other end is fixedly connected to the installation box. The second damping rod is provided with an annular groove, and the reagent strip is provided with a convex ring corresponding to the annular groove. The annular groove is provided with a notch, and the notch is used for the convex ring to be separated from the annular groove. The rotating mechanism is arranged inside the installation box.

3. A nucleic acid extraction kit according to claim 2, characterized in that: The rotating mechanism includes a ruler bar, a limit block, a button, a connecting rod and a gear. The ruler bar is slidably arranged on the limit block, and the limit block is arranged at the bottom of the installation box. One end of the ruler bar is hinged with a connecting rod, and the end of the connecting rod is hinged to the button. The upper end of the button passes through the top of the installation box and extends to the outside of the installation box. The gear is installed on the second damping rod and meshes with the ruler bar for transmission.

4. A nucleic acid extraction kit according to claim 1 or 2, characterized in that: The connecting member includes a groove plate, a sliding rod, a connecting plate and an elastic rod, one side of the groove plate is fixedly connected to the connecting plate, the connecting plate is connected to the protective box through a tension spring, two sliding rods are slidably arranged on the connecting plate, the sliding rod is fixedly connected to the protective box, the elastic rod is an L-shaped structure, the elastic rod is fixedly connected to the mounting box, a notch, a guide groove, a V-shaped groove and a disengagement groove are provided on the groove plate, the notch is connected to the guide groove, the guide groove is connected to one end of the V-shaped groove, the guide groove is arranged obliquely, the other end of the V-shaped groove is connected to the disengagement groove, the disengagement groove is connected to the guide groove, the disengagement groove is connected to the guide groove, and the depth of the disengagement groove is less than the depth of the guide groove.

5. A nucleic acid extraction kit according to claim 1, characterized in that: A box cover is rotatably arranged on the protection box.

6. A nucleic acid extraction kit according to claim 1, characterized in that: The groove plate is made of Teflon plastic.

7. A nucleic acid extraction kit according to claim 4, characterized in that: The elastic rod is made of spring steel.

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