Gene test method and gene test device

Abstract

The invention provides a gene testing method and a gene testing device. The gene test device (1) further comprises a calculation unit (2d) that adds a standby time corresponding to the priority of the sample to a time when the sample is introduced, and calculates a target time until the dispensing of the sample is completed, and the control unit (2c) performs dispensing processing of the sample in the order of the target time. As a result, it is possible to prioritize the measurement of specimens having high priorities, and to prevent the measurement of specimens having low priorities from becoming long-standing even if specimens having high priorities are continuously introduced.

Description

Technical Field

[0001] The present invention relates to a gene testing method and a gene testing device for extracting nucleic acid from a biological sample and performing gene amplification using a polymerase chain reaction (hereinafter referred to as PCR). Background Art

[0002] As an example of a specimen processing device that prevents the deterioration of specimens and reagents associated with a longer standby time other than reaction and achieves improved operating efficiency of the device, the following is recorded in Patent Document 1: It comprises: a plurality of reaction units, at least two of which independently react the specimens; an input / output terminal for inputting an upper limit of the standby time other than reaction of the specimen and a reaction time of the specimen; a schedule management unit that determines any one or more of the time of specimen input, the reaction unit used for processing the specimen, and the standby time other than reaction of the specimen based on the upper limit of the standby time other than reaction input by the input / output terminal and the reaction time; and an overall control unit that performs control so that the specimen is processed through the plurality of reaction units according to the decision of the schedule management unit.

[0003] Prior art literature

[0004] Patent Literature

[0005] Patent Document 1: Japanese Patent Application Publication No. 2008-039556 Summary of the invention

[0006] Problems to be solved by the invention

[0007] The PCR method is used in devices that analyze nucleic acids contained in samples from organisms such as blood and urine (so-called biological samples). The PCR method is a technology that uses heat-resistant polymerase and primers to amplify target nucleic acids by raising and lowering the temperature, and is widely used in the fields of genetic engineering, biological experiments, and biological detection methods.

[0008] The principle of PCR is to amplify the target DNA in a geometric manner by repeating a cycle according to a thermal profile (temperature rise and fall) multiple times.

[0009] Quantitative testing methods that apply such PCR methods include real-time PCR or quantitative polymerase chain reaction (hereinafter referred to as qPCR). qPCR is a highly sensitive gene analysis method, and its application in clinical tests such as quantitative gene expression analysis, pathogen detection, and pharmaceutical target verification is being promoted.

[0010] Genetic testing using these technologies requires about 2 hours because the extraction process and PCR measurement process are performed all at once. In addition, genetic testing using these technologies is generally a batch processing method in which a plurality of biological samples are processed all at once.

[0011] In recent years, these gene testing devices have become popular, mainly in university hospitals and clinical testing centers that need to process biological samples of many patients in a short period of time. However, in these hospitals, the rapid diagnosis of patients who need to be treated urgently is a problem. In addition, in projects such as airborne infections using air as a medium, if the results cannot be judged quickly, it will also lead to secondary infections in the hospital. Therefore, there is a very high demand for the rapid diagnosis required to take quick measures.

[0012] Under these circumstances, there is an increasing demand for rapid measurement of emergency specimens in gene testing devices.

[0013] As a prior art, attempts to rapidly measure urgent specimens have been proposed. For example, Patent Document 1 proposes setting an upper limit on the waiting time of specimens other than reaction and controlling the loading of specimens within this time.

[0014] However, in actual operation in hospitals, blood samples are collected and collected in advance, and these samples are put into the device at any time after arriving at the examination room. In other words, it can be said that the device is the main body and it is difficult to control the timing of the sample to be carried in.

[0015] As mentioned above, gene testing devices are generally batch processing systems that process multiple biological samples at once. This is because one measurement takes several hours, so the number of measurements per unit time is ensured by measuring multiple identical measurements simultaneously. In the case of use for research purposes such as pharmaceuticals, the priority of each specimen is the same, and the items to be measured are also the same, so even this method does not cause any major problems.

[0016] However, when measuring biological samples of unspecified patients, the priority and the inspection items also differ for each sample. Furthermore, the conditions under which the sample arrives at the inspection room and becomes ready for measurement also differ for each sample.

[0017] Therefore, it is necessary to perform processing according to the priority order corresponding to the specimen and the inspection item. In particular, it is necessary to preferentially measure an urgent specimen determined to have a high priority.

[0018] However, if priority processing is simply performed based on the priority of the specimens, for example, when specimens with high priority are continuously input, the processing of specimens with low priority will be constantly put on hold, and results may not be obtained at any time.

[0019] In addition, in such a gene testing device for hospitals, the structure is that only the specimen is inserted at the place where the specimen is inserted. That is, the inspection technician only inserts the arrived specimens one by one. On the other hand, inside the device, it is a structure that extracts and processes multiple specimens together. In addition, the PCR process also becomes a structure that measures and processes multiple specimens together. That is, if multiple items are not measured and processed together, there is still a problem of reduced overall efficiency.

[0020] Furthermore, since PCR measurement also requires several hours, if the sample is left at room temperature for an excessively long period of time, it may cause evaporation and other degradation of the sample, which is not preferable.

[0021] Therefore, the input samples should be processed quickly, but it is necessary to implement measurement processing that is also aware of the priority of the samples and the operating efficiency of the equipment.

[0022] The present invention provides a gene testing method and a gene testing device which can give priority to the measurement of a sample with a high priority and avoid the long waiting time for the measurement of a sample with a low priority even if the samples with a high priority are continuously input.

[0023] Means for solving problems

[0024] The present invention includes multiple means for solving the above-mentioned problems. As an example, a genetic testing method executes: an input step of inputting a sample; a pretreatment step of obtaining biological molecules containing a measurement object from the sample input in the input step; a measurement step of measuring the biological molecules obtained in the pretreatment step; and an analytical data processing step of performing analytical calculations based on the measurement results in the measurement step. The genetic testing method also executes: an calculation step of adding a standby time corresponding to the priority of the sample to the time when the sample is input, and calculating a target time until the injection of the sample is completed, and performing injection processing of the sample in the order of the target times.

[0025] Effects of the Invention

[0026] According to the present invention, it is possible to prioritize the measurement of samples with high priority, and even if samples with high priority are continuously input, it is possible to avoid long waiting for the measurement of samples with low priority. Other problems, structures, and effects will become clear from the following description of the embodiments. BRIEF DESCRIPTION OF THE DRAWINGS

[0027] Figure 1 This is a diagram showing an embodiment of a gene testing device to which the present invention is applied.

[0028] Figure 2This is a diagram showing a setting screen for a sample to be aliquoted used in one embodiment of a genetic testing apparatus to which the present invention is applied.

[0029] Figure 3 This is a diagram showing a sample and a sample rack used in one embodiment of a gene testing apparatus to which the present invention is applied.

[0030] Figure 4 This is an example of a flow chart for calculating the end-of-injection target in one embodiment of the gene testing device to which the present invention is applied.

[0031] Figure 5 This is a diagram showing an example of an injection order management table in one embodiment of the gene testing device to which the present invention is applied.

[0032] Figure 6 This is a diagram showing an example of an injection order management table in one embodiment of the gene testing device to which the present invention is applied.

[0033] Figure 7 This is a diagram showing an example of an injection order management table in one embodiment of the gene testing device to which the present invention is applied. DETAILED DESCRIPTION

[0034] use Figures 1 to 7 Embodiments of the gene testing method and the gene testing device of the present invention will be described. In the drawings used in this specification, the same or corresponding components are denoted by the same or similar reference numerals, and repeated descriptions of these components may be omitted.

[0035] First, use Figure 1 The overall structure of the gene testing device is described. Figure 1 1 is a block diagram showing an outline of the gene testing apparatus of this embodiment. Here, it is assumed that the gene testing apparatus 1 transports a specimen rack carrying a plurality of specimen containers.

[0036] Figure 1 The gene testing apparatus 1 shown includes a sample rack input unit 11, a sample rack buffer unit 12, a first dispensing unit 16a, nucleic acid extracting units 13a, 13b, a second dispensing unit 16b, amplifying units 14a, 14b, 14c, a control computer 2, and the like.

[0037] The specimen rack loading unit 11 is a part for loading and collecting specimen racks, and has a barcode reader 11a for reading the priority of specimens when the specimens are loaded. The specimen rack loading unit 11 appropriately performs a loading step for loading specimens, and the barcode reader 11a appropriately performs a reading step for reading the priority of specimens when the specimens are loaded.

[0038] The specimen rack buffer 12 is a portion that temporarily stores one or more specimen racks that hold specimen containers containing specimens to be analyzed that are loaded from the specimen rack loading unit 11 and temporarily stores one or more specimen racks before being collected.

[0039] The first dispensing unit 16a is a part that dispenses samples from the sample container placed on the sample rack on the sample rack input unit 11 or the sample rack buffer unit 12 to the nucleic acid extraction units 13a and 13b, and has a driving mechanism and a dispensing probe in the X-axis, Y-axis and Z-axis directions, and moves above the sample rack input unit 11, the sample rack buffer unit 12 and the nucleic acid extraction units 13a and 13b. In the first dispensing unit 16a, the first dispensing step of dispensing the sample from the input step to the pretreatment step is appropriately performed.

[0040] The nucleic acid extracting units 13a and 13b are parts that obtain biological molecules including the measurement target from the sample loaded into the sample rack loading unit 11. In the nucleic acid extracting units 13a and 13b, a pre-processing step for obtaining biological molecules including the measurement target from the sample loaded in the loading step is appropriately performed.

[0041] The second dispensing unit 16b is a part that dispenses biomolecules from the nucleic acid extraction units 13a and 13b to the amplification units 14a, 14b and 14c. Like the first dispensing unit 16a, it has a driving mechanism and a dispensing probe in the X-axis, Y-axis and Z-axis directions, and moves above the nucleic acid extraction units 13a and 13b and the amplification units 14a, 14b and 14c. In the second dispensing unit 16b, the second dispensing step of dispensing biomolecules from the pretreatment step to the measurement step is appropriately performed.

[0042] The amplification units 14a, 14b, and 14c are parts for measuring the biomolecules obtained by the nucleic acid extraction units 13a and 13b. In the amplification units 14a, 14b, and 14c, a measurement step for measuring the biomolecules obtained in the pre-processing step is appropriately performed.

[0043] Here, an example is shown in which the nucleic acid extraction units 13a and 13b are composed of two units, a and b, and the amplification units 14a, 14b, and 14c are composed of three units, a, b, and c, but this number is an example, and it can be one or more than four. Similarly, an example is shown in which the first dispensing unit 16a or the second dispensing unit 16b is also composed of one unit, but it can also be composed of two or more units.

[0044] Furthermore, the control computer 2 is connected to the gene testing device 1 via a communication line 3 .

[0045] The control computer 2 is composed of a display unit 2a, an analysis data processing unit 2b, a control unit 2c, a calculation unit 2d, an information storage unit 2e, and the like.

[0046] The display unit 2a is a touch panel type display also serving as an input unit, and displays various information related to the gene testing apparatus 1, information related to the sample to be analyzed, and information required for executing the analysis. In addition, the input unit may include an input device such as a mouse or a keyboard.

[0047] The analysis data processing unit 2b is a part that performs analysis calculation processing based on the measurement results in the amplification units 14a, 14b, and 14c. The analysis data processing unit 2b appropriately executes an analysis data processing step of performing analysis calculation processing based on the measurement results in the measurement step.

[0048] The control unit 2c is a part that controls the operation of each unit in the gene testing device 1 individually or as a whole. In the present embodiment, the control unit 2c controls the operation of the first dispensing unit 16a so as to perform the dispensing process of the specimen in the order of the target time obtained in the calculation unit 2d described later, specifically, the dispensing process of the specimen is performed in the order of the target time.

[0049] In addition, the control unit 2c can issue a warning when the target time has passed.

[0050] In the control unit 2c, a warning step of issuing a warning is executed when the target time has passed, and a first dispensing step is executed so that the sample dispensing process is performed in the order of the target time.

[0051] The operation unit 2d is a part that calculates a target time until the aliquoting of the specimen is completed by adding a waiting time corresponding to the priority of the specimen to the time when the specimen is introduced. In the operation unit 2d, an operation step of calculating a target time until the aliquoting of the specimen is completed by adding a waiting time corresponding to the priority of the specimen to the time when the specimen is introduced is appropriately performed.

[0052] The information storage unit 2e is a recording medium that stores, for example, control parameters corresponding to each unit, sample information related to various samples, and confirms and stores priorities. The information storage step of confirming and storing priorities is appropriately performed in the information storage unit 2e.

[0053] The analysis data processing unit 2b, the control unit 2c and the computing unit 2d in the control computer 2 can be constituted as hardware by a dedicated circuit substrate, or can be constituted by software executed by a computer. In the case of being constituted by hardware, it can be realized by integrating multiple computing units that perform processing on a wiring substrate, or in a semiconductor chip or package. In the case of being constituted by software, it can be realized by carrying a high-speed general-purpose CPU on the computer and executing a program for executing the desired computing processing. It is also possible to upgrade the existing device by recording the program on a recording medium. In addition, these devices, circuits, and computers are connected by a wired or wireless network to appropriately send and receive data.

[0054] The above is the structure of the gene testing device 1 of this embodiment.

[0055] The following briefly describes the flow of analysis in the gene testing device 1 .

[0056] The sample rack 31 on which the sample containers 33 are placed is provided in the sample rack loading section 11 , and when the analysis is started, the sample rack is introduced into the sample rack buffer section 12 .

[0057] In accordance with the requested items, the nucleic acid extraction units 13a and 13b perform the operation of extracting nucleic acid.

[0058] The extracted extract is transferred to the amplification sections 14a, 14b, and 14c, and reacts with the reagents set in the reagent setting section 15. Here, by repeatedly performing temperature control according to the thermal profile, the target DNA is amplified geometrically and detected.

[0059] The specimen container 33 is installed on Figure 3 The specimen rack 31 shown in the figure. Generally speaking, the specimen rack 31 has different colors according to the priority of the specimen to be set up. For example, the specimen rack for setting up emergency specimens is red, and the specimen rack for setting up general specimens is gray. This is used for the inspection technician to easily identify the specimen rack to be set up according to the priority of the specimen when setting up the specimen.

[0060] As a device, when directly recognizing colors, it is necessary to assemble expensive equipment such as image processing. Therefore, information that can identify the priority of the sample rack is recorded in the rack barcode 32, and the information is read by the barcode reader 11a, thereby identifying the priority of each sample mounted on the rack.

[0061] A sample barcode 34 for identifying the sample itself is attached to the sample container 33. This information is read by the barcode reader 11a, thereby identifying each sample.

[0062] Although not described in this document, the barcode information of the specimen and the request information for the specimen are registered as a pair in a host computer such as HIS (Hospital Information System). After reading the barcode information of the specimen, the device inquires the host computer to determine the request information to be measured for the specimen.

[0063] In addition, in this embodiment, a genetic testing device using a specimen rack is described, but the specimen does not necessarily need to be inserted through the specimen rack. It can be a genetic testing device using a specimen holder, or it can be a genetic testing device with a structure in which a testing technician directly sets the specimen.

[0064] In addition, the specimen rack is also Figure 3 Although five sample containers are arranged above, the number may be one, or may be ten or other different numbers, and there is no particular limitation.

[0065] The priority of the brought-in specimens is defined based on information from a host computer (omitted for convenience of illustration) or from specimen information, etc. Generally, there are general specimens that are handled as normal patient specimens and emergency specimens that must be measured quickly.

[0066] In the present embodiment, two priorities are defined, but three or more priorities may be set, such as 4. In this case, the configuration is such that the available waiting time is set for each priority, and the target time until each dispensing is completed is calculated.

[0067] exist Figure 2 In the example, a sample-to-be-aliquoted setting screen 21 for registering the time during which the sample can wait in the apparatus is displayed on the display unit 2a according to these sample priorities.

[0068] In the sample setting screen 21 for aliquoting displayed on the display unit 2a, a general sample standby time setting column 22 for setting the standby time of the sample rack buffer 12 for general samples and an emergency sample standby time setting column 23 for setting the standby time of the sample rack buffer 12 for emergency samples can be input. The input setting of the general sample standby time setting column 22 and the emergency sample standby time setting column 23 constitutes a time setting step for setting the standby time.

[0069] The settings of the sample setting screen 21 are set in advance by the hospital manager or by the service personnel when the device is installed.

[0070] When the OK button 26 is pressed, the input value is recorded as the available waiting time, and when the Cancel button 27 is pressed, the sample to be aliquoted setting screen 21 is closed.

[0071] Next, use Figures 4 to 7 The process of scheduling sample aliquoting and analysis, which is the gist of the present invention, will be described.

[0072] As described above, generally speaking, regarding the specimen, the specimen container containing the specimen is placed on the specimen rack 31, and the rack barcode 32 and the specimen barcode 34 are read by the barcode reader 11a and then placed in the specimen rack loading unit 11. Figure 4 The process determines the target time for ending the bet.

[0073] like Figure 4 As shown, in the calculation unit 2d, the aliquoting end target time calculation process is started when the sample is put in.

[0074] First, the sample priority is determined in the calculation unit 2d (S101). If the sample priority is a general sample, the process proceeds to S102, and the sample standby time, i.e., the target time for the dispensing to be completed, is determined by the calculation formula "target dispensing completion time" = "rack input time" + "general sample standby time (time input to the general sample standby time setting column 22)", and the process is terminated.

[0075] In contrast, when the specimen priority is an emergency specimen, the processing enters S103, and the specimen waiting time, i.e., the target time for the aliquoting to end (S103), is determined by the calculation formula "target time for the aliquoting to end" = "time when the rack is put into the rack" + "emergency specimen waiting time (time entered into the emergency specimen waiting time setting column 23)", and the processing is ended.

[0076] This result is reflected in Figure 5 The dispensing order management table 201 is in the dispensing order management table 201.

[0077] Here, it is assumed that the waiting time for general specimens is set to 40 minutes and the waiting time for emergency specimens is set to 20 minutes. As specimens are sequentially introduced from 08:45 to 09:00, a target dispensing completion time is determined, and therefore, the specimens are sequentially arranged according to the time.

[0078] Afterwards, if Figure 6 As shown, when an urgent specimen with specimen ID 0000101 is carried in at 09:15, the target aliquoting completion time is calculated to be 09:35 in S103, and these information are generated as the aliquoting order management table 202.

[0079] This information is added to the dispensing order management table 201, such as Figure 7 As shown, the aliquoting order management table 203 after the emergency specimen is brought in is created. Here, the target aliquoting completion time of the additional emergency specimen is 09:35, so it is the same time as the specimen ID, 0000003. If it is the same time, it is registered first according to the priority of the specimen. There is no problem in the logic of giving priority to the first input.

[0080] The sample introduced into the apparatus is dispensed according to the dispensing order management table 203, and is measured through the nucleic acid extraction units 13a, 13b, and the amplification units 14a, 14b, and 14c.

[0081] If we simply consider it, the aliquoting order management table 203 is created according to the priority of the specimens. In this case, the emergency specimen with specimen ID 0000101 is arranged at the front. After that, if the emergency specimens arrive successively, the emergency specimens are allocated before the general specimen with specimen ID 0000001, and the general specimens cannot be measured no matter how much time has passed. In other words, there is a possibility that the specimens will deteriorate.

[0082] However, in this embodiment, a waiting time limit is set for general samples, so that the rapidity of measurement based on the insertion of emergency samples can be maintained, and the delay of general samples caused by the insertion can be minimized. That is, a genetic testing device can be provided that can prevent the degradation of samples that affect the analysis performance due to long-term waiting in the device.

[0083] Here, in this embodiment, a system is considered in which there are two nucleic acid extraction units 13a and 13b and three amplification units 14a, 14b, and 14c.

[0084] If any one of the devices fails, for example, one of the nucleic acid extraction units 13a and 13b fails and only one of them has to operate, the nucleic acid extraction process of all the specimens must be processed, so the overall processing speed has to be reduced. In such a case, the specimen dispensing may not be completed before the target dispensing completion time, and there is a high possibility that it will exceed the target dispensing completion time.

[0085] In order to prevent such a situation, a warning can be issued to the operator according to the setting of the possible standby time exceeded warning setting column 24. The operator can recognize that the set time has been exceeded by this warning.

[0086] When the target time has passed, the measurement continuation setting field 25 for setting whether to perform the measurement of the corresponding sample when the available waiting time has passed can be used to directly wait for aliquoting even if the time has passed, or to cancel the measurement and collect the sample.

[0087] When the input setting of the measurement continuation setting field 25 when the available standby time is exceeded exceeds the target time, it becomes a setting step to set whether to perform the measurement of the corresponding sample.

[0088] Next, the effects of this embodiment will be described.

[0089] The genetic testing device 1 of the present embodiment described above comprises: a specimen rack insertion section 11 for inserting a specimen; a nucleic acid extraction section 13a, 13b for obtaining biological molecules containing a measurement object from the specimen inserted into the specimen rack insertion section 11; an amplification section 14a, 14b, 14c for measuring the biological molecules obtained by the nucleic acid extraction section 13a, 13b; an analysis data processing section 2b for performing analysis and calculation based on the measurement results in the amplification sections 14a, 14b, 14c; and a control section 2c for controlling the operation of each section in the device individually or as a whole, and further comprises a calculation section 2d for calculating a target time until the injection of the specimen is completed by adding a standby time corresponding to the priority level of the specimen to the time when the specimen is inserted, and the control section 2c performs the injection processing of the specimen in the order of the target times.

[0090] In such a gene testing device 1, by processing samples in order of the shortest validity period to the longest, the measurement of samples with high priority can be prioritized. On the other hand, since the processing is not performed only by priority, even if samples with high priority are continuously input, the measurement of samples with low priority can be prevented from having to wait for a long time.

[0091] In addition, there are a general sample standby time setting column 22 and an emergency sample standby time setting column 23 for setting the standby time. Therefore, the standby time can be changed in time according to the operation status of the device and the actual situation of the operator, which can realize more flexible analysis.

[0092] Furthermore, the barcode reader 11a is provided to read the priority of the specimen when the specimen is put in, thereby eliminating the need for the user to manually input the priority one by one, and thus the burden can be reduced.

[0093] Furthermore, the control unit 2c issues a warning when the target time has passed, thereby being able to determine whether measures such as recollection or re-injection of the sample are necessary, thereby being able to obtain accurate analysis results even when a failure or the like occurs.

[0094] Furthermore, there is a setting column 25 for setting whether to carry out the measurement of the corresponding sample when the target time is exceeded, thereby making it possible to set whether to directly analyze the sample that may deteriorate due to long-term standby time according to the operating status of the device and the actual situation of the operator, thereby achieving more flexible analysis.

[0095] In addition, there is also a first dispensing unit 16a for dispensing the sample from the sample rack input unit 11 to the nucleic acid extraction units 13a, 13b, and a second dispensing unit 16b for dispensing biological molecules from the nucleic acid extraction units 13a, 13b to the amplification units 14a, 14b, 14c. The control unit 2c controls the operation of the first dispensing unit to perform the sample dispensing process in the order of target time. Thus, the operation of the first dispensing unit 16a for directly dispensing the sample that has the greatest impact on the degradation of the sample can be used as an action to give priority to the measurement of the high-priority sample and also avoid making the measurement of the low-priority sample wait for a long time.

[0096] <Others>

[0097] The present invention is not limited to the above-described embodiments, and various modifications and applications are possible. The above-described embodiments are examples described in detail to explain the present invention in an easy-to-understand manner, and are not necessarily limited to having all the described structures.

[0098] Explanation of symbols

[0099] 1: Genetic testing device

[0100] 2: Control computer

[0101] 2a: Display unit

[0102] 2b: Analytical Data Processing Department

[0103] 2c: Control Unit

[0104] 2d: Operation unit

[0105] 2e: Information storage unit

[0106] 3: Communication lines

[0107] 11: Sample rack loading section (loading section)

[0108] 11a: Barcode reader

[0109] 12: Specimen rack buffer

[0110] 13a, 13b: Nucleic acid extraction unit (pretreatment unit)

[0111] 14a, 14b, 14c: Amplification section (measurement section)

[0112] 15: Reagent Setting Section

[0113] 16a: First note section

[0114] 16b: Second Note

[0115] 21: Sample setup screen

[0116] 22: General specimen standby time setting column

[0117] 23: Emergency specimen standby time setting column

[0118] 24: Warning setting column when standby time exceeds

[0119] 25: Setting column for continuing measurement when standby time is exceeded (setting section)

[0120] 26: OK button

[0121] 27: Cancel button

[0122] 31: Specimen rack

[0123] 32: Barcode rack

[0124] 33: Sample container

[0125] 34: Sample barcode

[0126] 201, 202, 203: Note order management table.

Claims

1. A genetic testing method, performing: Input step: input the specimen; a pre-processing step of obtaining biological molecules including a measurement target from the sample introduced in the introducing step; a measuring step of measuring the biomolecules obtained in the pretreatment step; and an analysis data processing step of performing analysis calculation processing based on the measurement results in the measurement step, It is characterized in that The gene testing method further comprises: a calculation step of adding a waiting time corresponding to the priority of the sample to the time when the sample is injected, and calculating a target time until the injection of the sample is completed; The sample aliquoting process is performed in the order of the target time.

2. The gene testing method according to claim 1, characterized in that: The gene inspection method further performs: a time setting step of setting the standby time.

3. The gene testing method according to claim 1, characterized in that: The gene testing method further includes executing a reading step of reading a priority level of the sample when the sample is input.

4. The gene testing method according to claim 1, characterized in that: The gene inspection method further performs: an information storage step of confirming and storing the priority.

5. The gene testing method according to claim 1, characterized in that: The gene inspection method further executes: a warning step of issuing a warning when the target time is exceeded.

6. The gene testing method according to claim 1, characterized in that: The gene testing method further includes performing a setting step of setting whether to perform measurement of the corresponding sample when the target time has passed.

7. The gene testing method according to claim 1, characterized in that: The gene testing method further comprises: a first dispensing step of dispensing the sample from the inputting step to the pre-processing step; and The second dispensing step is to dispense the biomolecule from the pretreatment step to the measurement step, The first dispensing step is executed so as to perform dispensing processing of the sample in the order of the target time.

8. A gene testing device comprising: an input section for inputting a specimen; a pre-processing unit for obtaining biological molecules including a measurement target from the sample introduced into the introduction unit; a measuring unit that measures the biomolecules obtained by the pre-processing unit; an analysis data processing unit that performs analysis calculation processing based on the measurement results in the measurement unit; and A control unit that controls the operation of each unit in the device individually or as a whole, It is characterized in that The gene testing device further comprises: a calculation unit that adds a waiting time corresponding to the priority of the sample to the time when the sample is injected, and calculates a target time until the injection of the sample is completed. The control unit performs aliquoting of the sample in the order of the target time.

9. The gene testing device according to claim 8, characterized in that: The gene testing device further includes a time setting unit that sets the possible standby time.

10. The gene testing device according to claim 8, characterized in that: The gene testing device further includes a reading unit that reads the priority level of the sample when the sample is input.

11. The gene testing device according to claim 8, characterized in that: The gene testing device further includes an information storage unit that confirms and stores the priority level.

12. The gene testing device according to claim 8, characterized in that: The control unit issues a warning when the target time has passed.

13. The gene testing device according to claim 8, characterized in that: The gene testing device further includes a setting unit that sets whether to perform measurement of the corresponding sample when the target time has passed.

14. The gene testing device according to claim 8, characterized in that The gene testing device further comprises: a first dispensing unit that dispenses the sample from the input unit to the pretreatment unit; and a second dispensing unit for dispensing the biomolecule from the pretreatment unit to the measurement unit, The control unit controls the operation of the first dispensing unit so as to perform the dispensing process of the sample in the order of the target time.

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