Food composition for promoting neural development and preparation process thereof

Abstract

The invention provides a food composition for promoting neural development and a preparation process thereof. The food composition is prepared from the following raw materials in parts by weight: 20 to 30 parts of whey protein powder, 10 to 20 parts of DHA algae oil powder, 15 to 20 parts of walnut powder, 10 to 15 parts of oat powder, 0.5 to 1.0 part of choline, 0.1 to 0.3 part of hericium erinaceus extract, 1 to 2 parts of annona squamosa polysaccharide, 0.1 to 0.3 part of vitamin C, 0.2 to 0.4 part of compound vitamin B, 0.2 to 0.5 part of folic acid, 1.0 to 1.5 parts of phosphatidylserine, 0.5 to 1.0 part of taurine and 0.05 to 0.10 part of compound trace elements. Wherein the DHA algal oil powder and the phosphatidylserine mutually promote absorption, so that the DHA algal oil powder and the phosphatidylserine are mutually linked on a nerve cell membrane, and the development and functions of nerve cells are jointly promoted. The hericium erinaceus extract and the annona squamosa polysaccharide are beneficial to maintaining normal structures and functions of neurons by resisting oxidative stress, so that the neurons can be ensured to be capable of normally synthesizing and releasing neurotransmitters, and neurodevelopment is promoted.

Description

Technical Field

[0001] The invention relates to the field of food, and in particular to a food composition for promoting nerve development and a preparation process thereof. Background Art

[0002] Neurodevelopment is extremely important to humans. First of all, the normal development of the nervous system is the basis for the development of intelligence, emotions and behavior. In the early stages of life, the neuronal connections of the brain are developing rapidly, laying the foundation for the subsequent intellectual, emotional and behavioral development of children. Neurodevelopment at this stage is not only related to innate genetic factors, but also closely related to factors such as diet and reasonable sensory stimulation. Good neurodevelopment helps children develop good communication and interpersonal skills, as well as emotional and behavioral regulation abilities. Secondly, neurodevelopment is also crucial to the health and quality of life of adults. Although the adult brain no longer increases neurons as much as in childhood, the lengthening, branching and complexity of nerve fiber networks are still ongoing. In order to promote neurodevelopment, a reasonable diet plays a vital role. Foods rich in protein, vitamins and minerals contribute to the development and health of the nervous system. The combined intake of these foods not only contributes to neurodevelopment, but also enhances learning, memory and thinking abilities, while protecting the nervous system. In the current market, food compositions specifically designed to promote neurodevelopment are relatively rare. Given the importance of neurodevelopment to the development of human intelligence, emotions and behavior, developing scientifically formulated, safe and effective food compositions that promote neurodevelopment is of great significance for meeting the nutritional needs of specific populations and improving public health. Summary of the invention

[0003] In view of this, the present invention provides a food composition for promoting neural development and a preparation process thereof to solve the above problems.

[0004] The technical solution of the present invention is achieved as follows: a food composition for promoting neural development, comprising the following raw materials in parts by weight: 20-30 parts of whey protein powder, 10-20 parts of DHA algae oil powder, 15-20 parts of walnut powder, 10-15 parts of oatmeal powder, 0.5-1.0 parts of choline, 0.1-0.3 parts of Hericium erinaceus extract, 1-2 parts of soursop polysaccharide, 0.1-0.3 parts of vitamin C, 0.2-0.4 parts of complex vitamin B, 0.2-0.5 parts of folic acid, 1.0-1.5 parts of phosphatidylserine, 0.5-1.0 parts of taurine, and 0.05-0.10 parts of complex trace elements.

[0005] Furthermore, a food composition for promoting neural development comprises the following raw materials in parts by weight: 25 parts of whey protein powder, 15 parts of DHA algae oil powder, 18 parts of walnut powder, 12 parts of oatmeal powder, 0.7 parts of choline, 0.2 parts of Hericium erinaceus extract, 1.5 parts of soursop polysaccharide, 0.2 parts of vitamin C, 0.3 parts of vitamin B complex, 0.35 parts of folic acid, 1.3 parts of phosphatidylserine, 0.75 parts of taurine, and 0.08 parts of complex trace elements.

[0006] Furthermore, the Hericium erinaceus extract is obtained by the following method: dried Hericium erinaceus fruiting bodies are crushed using a crusher to obtain Hericium erinaceus powder, and purified water is added to the Hericium erinaceus powder for extraction, wherein the amount of water added for the first time is 6-10 times the weight of the Hericium erinaceus powder, and the extraction time is 2-4 hours; the amount of water added for the second time is 8-12 times the weight of the Hericium erinaceus powder, and the extraction time is 1.5-2.5 hours; after the extraction is completed, the extraction is filtered, the filtrate is taken, and it is concentrated under reduced pressure to 30-50% of the volume of the original solution; the concentrated filtrate is extracted with water-saturated n-butanol, wherein the volume ratio of the filtrate to n-butanol is 1:1-3, and extraction is performed 2 to 4 times; after the extraction is completed, the n-butanol extraction layer is decompressed to recover the solvent to obtain an extract; the extract is dried at 60-70°C, and then crushed to obtain the Hericium erinaceus extract.

[0007] Furthermore, the extraction is carried out in a water bath under heating conditions, and the heating temperature is 85-100°C.

[0008] Furthermore, the soursop polysaccharide is obtained by the following method: peeling and core-removing the soursop fruit, taking the pulp part, crushing the pulp into a pulp with a pulper to obtain pulp pulp, soaking the pulp pulp with ethanol, filtering out the ethanol after soaking, and taking the pulp pulp; drying the treated pulp pulp at 55-65° C., then crushing it with a crusher, adding distilled water to the pulp pulp at a solid-liquid ratio of 1:5-10, adjusting the pH value to neutral, placing it in a water bath for heating extraction, controlling the temperature at 75-85° C., and extracting for 2-4 hours; filtering and taking the filtrate after the extraction is completed, vacuum concentrating the filtrate to 20-30% of the volume of the original solution, adding a chloroform-n-butanol mixed solution to the concentrated filtrate, shaking at room temperature for 15-25 minutes, and then 2 The method comprises the steps of: centrifuging at 500-3500 rpm for 15-25 min, filtering and removing protein precipitates; repeating this step 3-5 times, wherein the volume ratio of the concentrated filtrate to the chloroform-n-butanol mixed solution is 1:3-4, wherein the chloroform-n-butanol mixed solution is composed of chloroform and n-butanol in a volume ratio of 4-5:1; adding 95 wt % edible alcohol to the filtrate after protein removal, wherein the amount of edible alcohol added is 40-60 % of the volume of the filtrate, standing at 4-6 DEG C for 10-12 h, then centrifuging at 4000-6000 rpm for 10-20 min, filtering and collecting precipitates, washing with 80 wt % ethanol for 2-3 times, and then drying the precipitates at 55-65 DEG C to constant weight, thereby obtaining soursop polysaccharide.

[0009] Furthermore, soaking with ethanol specifically comprises: soaking the pulp slurry with 95wt% ethanol, the volume ratio of the pulp slurry to the ethanol is 1:2-4, and the soaking condition is soaking at 40-50°C for 10-15h.

[0010] Furthermore, the vitamin B complex consists of B1, B6, and B12 in a mass ratio of (8-12):(4-7):(2-5).

[0011] Furthermore, the composite trace elements are composed of zinc, iron, copper and selenium in a mass ratio of (2.0-4.0):(2.0-3.5):(1.0-1.8):(0.5-0.9).

[0012] Furthermore, the preparation process of the above-mentioned food composition for promoting neural development comprises the following steps:

[0013] S1, weigh the raw materials by weight and set aside;

[0014] S2, adding whey protein powder, DHA algae oil powder, walnut powder and oatmeal powder into a blender for preliminary mixing to obtain mixture I;

[0015] S3, gradually adding choline, Hericium erinaceus extract, soursop polysaccharide, vitamin C, vitamin B complex, folic acid, phosphatidylserine, taurine and complex trace elements to mixed material I, stirring while adding, to obtain mixed material II;

[0016] S4. Place the mixture II into a dryer for drying to obtain a food composition for promoting nerve development.

[0017] Furthermore, in S2, the initial stirring speed is 100-200 rpm, and the stirring time is 10-15 min; in S3, the stirring speed while adding is 800-1200 rpm, and the stirring time is 5-10 min; in S4, the drying temperature is 40-60° C., and the drying time is 2-4 h.

[0018] Compared with the prior art, the invention has the following beneficial effects: by adding Hericium erinaceus extract, the invention can significantly reduce the number of active oxygen and increase the content of antioxidant enzymes, which helps to protect nerve cells from damage caused by oxidative stress, thereby maintaining the normal function of the nervous system. Through the antioxidant effect, it helps to protect neurons from damage caused by oxidative stress and helps the synthesis and release of neurotransmitters. By adding soursop polysaccharide, the damage of oxidative stress to neurons is reduced, which helps to maintain the normal structure and function of neurons and ensure that they can synthesize and release neurotransmitters normally. Soursop polysaccharide can be decomposed into glucose in the body to provide energy for neurons. By providing energy support, it helps to promote the synthesis and release of neurotransmitters. Through the mutual promotion and absorption of DHA algae oil powder and phosphatidylserine, the two are connected to each other on the nerve cell membrane and jointly promote the development and function of nerve cells. At the same time, the synergistic effect of the two can significantly improve the efficiency of nerve transmission, thereby helping to improve nerve development. DETAILED DESCRIPTION

[0019] In order to better understand the technical content of the present invention, specific embodiments are provided below to further illustrate the present invention.

[0020] Unless otherwise specified, the experimental methods used in the embodiments of the present invention are all conventional methods.

[0021] Unless otherwise specified, the materials, reagents, etc. used in the embodiments of the present invention can be obtained from commercial sources.

[0022] Example 1

[0023] A food composition for promoting neural development, comprising the following raw materials in parts by weight: 20 parts of whey protein powder, 10 parts of DHA algae oil powder, 15 parts of walnut powder, 10 parts of oatmeal powder, 0.5 parts of choline, 0.1 parts of Hericium erinaceus extract, 1 part of soursop polysaccharide, 0.1 parts of vitamin C, 0.2 parts of vitamin B complex, 0.2 parts of folic acid, 1.0 parts of phosphatidylserine, 0.5 parts of taurine, and 0.05 parts of complex trace elements. Among them, the vitamin B complex is composed of B1, B6, and B12 in a mass ratio of 8:4:2, and the complex trace elements are composed of zinc, iron, copper, and selenium in a mass ratio of 2.0:2.0:1.0:0.5.

[0024] The Hericium erinaceus extract is obtained by the following method: using a pulverizer to grind the dried Hericium erinaceus fruiting bodies to obtain Hericium erinaceus powder, adding purified water to the Hericium erinaceus powder for extraction, and performing water bath heating extraction under heating conditions, the heating temperature is 85°C, the amount of water added for the first time is 6 times the weight of the Hericium erinaceus powder, and the extraction time is 4h; the amount of water added for the second time is 8 times the weight of the Hericium erinaceus powder, and the extraction time is 2.5h; after the extraction is completed, filtering is performed, and the filtrate is taken and concentrated under reduced pressure to 50% of the volume of the original solution; the concentrated filtrate is extracted with water-saturated n-butanol, wherein the volume ratio of the filtrate to n-butanol is 1:1, and extraction is performed twice; after the extraction is completed, the n-butanol extraction layer is decompressed to recover the solvent to obtain an extract; the extract is dried at 60°C and then pulverized to obtain the Hericium erinaceus extract.

[0025] The soursop polysaccharide is obtained by the following method: peeling and core-removing soursop fruits, taking the pulp part, crushing the pulp into a pulp by a pulper to obtain pulp pulp, soaking the pulp pulp with 95wt% ethanol, the volume ratio of pulp pulp to ethanol is 1:2, and the soaking condition is soaking at 40°C for 15h, filtering out the ethanol after soaking, and taking the pulp pulp; drying the treated pulp pulp at 55°C, then crushing it with a grinder, adding distilled water at a solid-liquid ratio of 1:5, adjusting the pH value to neutral, placing it in a water bath for heating extraction, controlling the temperature at 75°C, and extracting for 4h; filtering and taking the filtrate after the extraction is completed, vacuum concentrating the filtrate to 30% of the volume of the original solution, and adding the concentrated filtrate to the filtrate. A chloroform-butanol mixture is added, shaken at room temperature for 15 minutes, then centrifuged at 2500 rpm for 25 minutes, and filtered to remove protein precipitation; repeat this step 3 times, wherein the volume ratio of the concentrated filtrate to the chloroform-butanol mixture is 1:3, and the chloroform-butanol mixture consists of chloroform and n-butanol in a volume ratio of 4:1; 95wt% edible alcohol is added to the filtrate after protein removal, wherein the amount of edible alcohol added is 40% of the volume of the filtrate, and the mixture is allowed to stand at 6°C for 12 hours, then centrifuged at 4000 rpm for 20 minutes, filtered and collected the precipitate, washed twice with 80wt% ethanol, and then dried the precipitate at 55°C to constant weight, so as to obtain soursop polysaccharide.

[0026] Example 2

[0027] A food composition for promoting neural development, comprising the following raw materials in parts by weight: 30 parts of whey protein powder, 20 parts of DHA algae oil powder, 20 parts of walnut powder, 15 parts of oatmeal powder, 1.0 part of choline, 0.3 parts of Hericium erinaceus extract, 2 parts of soursop polysaccharide, 0.3 parts of vitamin C, 0.4 parts of complex vitamin B, 0.5 parts of folic acid, 1.5 parts of phosphatidylserine, 1.0 parts of taurine, and 0.10 parts of complex trace elements. The complex vitamin B is composed of B1, B6, and B12 in a mass ratio of 12:4:2, and the complex trace elements are composed of zinc, iron, copper, and selenium in a mass ratio of 4.0:3.5:1.8:0.9.

[0028] The Hericium erinaceus extract is obtained by the following method: using a pulverizer to grind the dried Hericium erinaceus fruiting bodies to obtain Hericium erinaceus powder, adding purified water to the Hericium erinaceus powder for extraction, and performing water bath heating extraction under heating conditions, the heating temperature is 100°C, the amount of water added for the first time is 10 times the weight of the Hericium erinaceus powder, and the extraction time is 2h; the amount of water added for the second time is 12 times the weight of the Hericium erinaceus powder, and the extraction time is 1.5h; after the extraction is completed, filtering is performed, and the filtrate is taken and concentrated under reduced pressure to 30% of the volume of the original solution; the concentrated filtrate is extracted with water-saturated n-butanol, wherein the volume ratio of the filtrate to n-butanol is 1:3, and extraction is performed 4 times; after the extraction is completed, the n-butanol extraction layer is decompressed to recover the solvent to obtain an extract; the extract is dried at 70°C and then pulverized to obtain the Hericium erinaceus extract.

[0029] The soursop polysaccharide is obtained by the following method: peeling and core-removing soursop fruits, taking the pulp part, crushing the pulp into a pulp by a pulper to obtain pulp pulp, soaking the pulp pulp with 95wt% ethanol, the volume ratio of pulp pulp to ethanol is 1:4, and the soaking condition is immersion at 50°C for 10h, filtering out the ethanol after soaking, and taking the pulp pulp; drying the treated pulp pulp at 65°C, then crushing it with a grinder, adding distilled water at a solid-liquid ratio of 1:10, adjusting the pH value to neutral, placing it in a water bath for heating extraction, controlling the temperature at 85°C, and extracting for 2h; after the extraction is completed, filtering and taking the filtrate, vacuum concentrating the filtrate to 20% of the volume of the original solution, and adding The mixture was added with chloroform-butanol mixed solution, shaken at room temperature for 25 minutes, then centrifuged at 3500rpm for 15 minutes, and filtered to remove protein precipitate; this step was repeated 5 times, wherein the volume ratio of the concentrated filtrate to the chloroform-butanol mixed solution was 1:4, and the chloroform-butanol mixed solution consisted of chloroform and n-butanol in a volume ratio of 5:1; 95wt% edible alcohol was added to the filtrate after protein removal, wherein the amount of edible alcohol added was 60% of the volume of the filtrate, and the mixture was allowed to stand at 4°C for 10 hours, then centrifuged at 6000rpm for 10-20 minutes, filtered and collected the precipitate, washed with 80wt% ethanol 3 times, and then dried the precipitate at 65°C to constant weight, so as to obtain soursop polysaccharide.

[0030] Example 3

[0031] A food composition for promoting neural development, comprising the following raw materials in parts by weight: 25 parts of whey protein powder, 15 parts of DHA algae oil powder, 18 parts of walnut powder, 12 parts of oatmeal powder, 0.7 parts of choline, 0.2 parts of Hericium erinaceus extract, 1.5 parts of soursop polysaccharide, 0.2 parts of vitamin C, 0.3 parts of vitamin B complex, 0.35 parts of folic acid, 1.3 parts of phosphatidylserine, 0.75 parts of taurine, and 0.08 parts of complex trace elements. Among them, the vitamin B complex is composed of B1, B6, and B12 in a mass ratio of 10:5.5:3.5, and the complex trace elements are composed of zinc, iron, copper, and selenium in a mass ratio of 3.0:2.8:1.4:0.7.

[0032] The Hericium erinaceus extract is obtained by the following method: using a pulverizer to grind the dried Hericium erinaceus fruiting bodies to obtain Hericium erinaceus powder, adding purified water to the Hericium erinaceus powder for extraction, and performing water bath heating extraction under heating conditions, the heating temperature is 92°C, the amount of water added for the first time is 8 times the weight of the Hericium erinaceus powder, and the extraction time is 3 hours; the amount of water added for the second time is 10 times the weight of the Hericium erinaceus powder, and the extraction time is 2.0 hours; after the extraction is completed, filtering is performed, and the filtrate is taken and concentrated under reduced pressure to 40% of the volume of the original solution; the concentrated filtrate is extracted with water-saturated n-butanol, wherein the volume ratio of the filtrate to n-butanol is 1:2, and extraction is performed 3 times; after the extraction is completed, the n-butanol extraction layer is decompressed to recover the solvent to obtain an extract; the extract is dried at 65°C and then pulverized to obtain the Hericium erinaceus extract.

[0033] The soursop polysaccharide is obtained by the following method: peeling and core-removing soursop fruits, taking the pulp part, crushing the pulp into a pulp by a pulper to obtain pulp pulp, soaking the pulp pulp with 95wt% ethanol, the volume ratio of pulp pulp to ethanol is 1:3, the soaking condition is immersion at 45°C for 12.5h, filtering out the ethanol after soaking, and taking the pulp pulp; drying the treated pulp pulp at 60°C, then crushing it with a grinder, adding distilled water at a solid-liquid ratio of 1:7.5, adjusting the pH value to neutral, placing it in a water bath for heating extraction, controlling the temperature at 80°C, and extracting for 3h; after the extraction is completed, filtering and taking the filtrate, vacuum concentrating the filtrate to 25% of the volume of the original solution, and adding the concentrated filtrate to the filtrate. Add a chloroform-butanol mixture, shake at room temperature for 20 minutes, then centrifuge at 3000rpm for 20 minutes, and filter to remove protein precipitates; repeat this step 4 times, wherein the volume ratio of the concentrated filtrate to the chloroform-butanol mixture is 1:3.5, and the chloroform-butanol mixture consists of chloroform and n-butanol in a volume ratio of 4.5:1; add 95wt% edible alcohol to the filtrate after protein removal, wherein the amount of edible alcohol added is 50% of the volume of the filtrate, stand at 5°C for 11 hours, then centrifuge at 5000rpm for 15 minutes, filter and collect the precipitate, wash it with 80wt% ethanol 3 times, and then dry the precipitate at 60°C to constant weight, so as to obtain soursop polysaccharide.

[0034] The food composition for promoting neural development described in the above embodiments 1-3 is prepared according to the following process, comprising the following steps:

[0035] S1. Weigh the raw materials by weight and set aside.

[0036] S2. Add whey protein powder, DHA algae oil powder, walnut powder and oatmeal powder into a blender for preliminary mixing, and stir at 150 rpm for 12.5 min to obtain mixture I.

[0037] S3. Gradually add choline, Hericium erinaceus extract, soursop polysaccharide, vitamin C, vitamin B complex, folic acid, phosphatidylserine, taurine and complex trace elements to mixture I, stirring at 1000 rpm for 7.5 minutes to obtain mixture II.

[0038] S4. Place the mixture II in a dryer and dry it at 50° C. for 3 hours to obtain a food composition for promoting neural development.

[0039] Example 4

[0040] Compared with Example 3, this embodiment is different in that the food composition for promoting neural development is prepared according to the following process, including the following steps:

[0041] S1. Weigh the raw materials by weight and set aside.

[0042] S2. Add whey protein powder, DHA algae oil powder, walnut powder and oatmeal powder into a blender for preliminary mixing, and stir at 100 rpm for 15 min to obtain mixture I.

[0043] S3. Gradually add choline, Hericium erinaceus extract, soursop polysaccharide, vitamin C, vitamin B complex, folic acid, phosphatidylserine, taurine and complex trace elements to mixed material I, stirring at 800 rpm for 10 minutes to obtain mixed material II.

[0044] S4. Place the mixture II in a dryer and dry it at 40° C. for 4 hours to obtain a food composition for promoting neural development.

[0045] Example 5

[0046] Compared with Example 3, this embodiment is different in that the food composition for promoting neural development is prepared according to the following process, including the following steps:

[0047] S1. Weigh the raw materials by weight and set aside.

[0048] S2. Add whey protein powder, DHA algae oil powder, walnut powder and oatmeal powder into a blender for preliminary mixing, and stir at 200 rpm for 10 min to obtain mixture I.

[0049] S3. Gradually add choline, Hericium erinaceus extract, soursop polysaccharide, vitamin C, vitamin B complex, folic acid, phosphatidylserine, taurine and complex trace elements to mixed material I, stirring at 1200 rpm for 5 minutes to obtain mixed material II.

[0050] S4, placing the mixed material II in a dryer and drying it at 60°C for 2 hours to obtain a food composition that promotes neural development

[0051] Comparative Example 1

[0052] The difference between this comparative example and Example 3 is that the raw material does not contain Hericium erinaceus extract.

[0053] Comparative Example 2

[0054] The difference between this comparative example and Example 3 is that the raw material does not contain soursop polysaccharide.

[0055] Comparative Example 3

[0056] The difference between this comparative example and Example 3 is that the raw material does not contain DHA algae oil powder.

[0057] Comparative Example 4

[0058] The difference between this comparative example and Example 3 is that the raw material does not contain phosphatidylserine.

[0059] Animal experiments

[0060] Select 25-day-old weaned mice, weighing 19-20g, of which 50 female mice and 50 male mice were randomly divided into 10 groups, each group of 5 female mice and 5 male mice, and fed the food compositions of Examples 1-5 and Comparative Examples 1-4 in equal amounts every day, and another group was fed with commercially available feed as a control example. When the mice were 45 days old, blood was collected from the experimental mice using anticoagulant tubes after anesthesia. The blood samples were centrifuged at 3000r / min for 15min at 4°C to separate the plasma. The plasma samples were stored in a -70°C refrigerator for standby use. Take out the plasma samples and thaw at room temperature. Measure the plasma samples, add formic acid methanol and vortex to mix, place at 4°C for 20min, then centrifuge at 15000rpm for 15min, take the supernatant to determine the content of acetylcholine, dopamine, 5-hydroxytryptamine, and norepinephrine, and the average value of the results of each group is recorded in Table 1.

[0061] Table 1

[0062]

[0063]

[0064] As can be seen from Table 1, the acetylcholine, dopamine, 5-hydroxytryptamine and norepinephrine contents of Examples 1-5 are all higher than those of Comparative Examples 1-4, and the acetylcholine, dopamine, 5-hydroxytryptamine and norepinephrine contents of Examples 1-5 and Comparative Examples 1-4 are all higher than those of the control example, which shows that the food composition of the present invention can effectively promote neural development.

[0065] Compared with Comparative Example 1 from Example 3, the Hericium erinaceus extract in Example 3 has a strong antioxidant capacity, can significantly reduce the number of reactive oxygen species, and increase the content of antioxidant enzymes, which helps to protect nerve cells from damage by oxidative stress, thereby maintaining the normal function of the nervous system. In addition, the Hericium erinaceus extract can regulate signal pathways such as brain-derived neurotrophic factor, phosphatidylinositol 3-kinase, serine protein kinase, glycogen synthase kinase-3β, which play a key role in neural development and neuroprotection. By regulating these signal pathways, the Hericium erinaceus extract can enhance the survival of neurons, promote neurite growth and synapse occurrence, thereby contributing to neural development. In addition, the Hericium erinaceus extract can promote the synthesis of neurotransmitter precursors such as amino acids and monoamines, thereby promoting the synthesis of neurotransmitters. At the same time, the Hericium erinaceus polysaccharide in the Hericium erinaceus extract can also increase the release of neurotransmitters such as dopamine and acetylcholine, thereby improving the function of the nervous system. Therefore, Hericium erinaceus extract has a positive effect on the synthesis and release of neurotransmitters through multiple pathways such as anti-oxidation, regulating the expression of neurotransmitter-related genes, promoting the synthesis of neurotransmitter precursors, and enhancing the release of neurotransmitters, which helps promote neural development.

[0066] Compared with Comparative Example 2 from Example 3, the soursop polysaccharide in Example 3 can directly inhibit the production of reactive oxygen species induced by hydrogen peroxide, thereby reducing the damage of oxidative stress to neurons. At the same time, it can also inhibit excessive mitogen-activated protein kinase signaling pathways, which are activated in oxidative stress and inflammatory responses, causing damage to neurons. By protecting neurons from oxidative stress, soursop polysaccharides help maintain the normal structure and function of neurons, ensuring that they can synthesize and release neurotransmitters normally. Soursop polysaccharides can be decomposed into glucose in the body to provide energy for neurons. The synthesis and release of neurotransmitters such as acetylcholine, dopamine, 5-hydroxytryptamine, and norepinephrine all require energy consumption. Therefore, soursop polysaccharides help promote the synthesis and release of these neurotransmitters by providing energy support.

[0067] Compared with comparative examples 3-4, DHA algae oil powder must work synergistically with phosphatidylserine to achieve a more effective effect of promoting neural development, because DHA and phosphatidylserine have a mutually promoting effect in the brain. DHA can promote the accumulation of phosphatidylserine, and phosphatidylserine can help DHA to be better transported to the brain's action site. This mutually promoting absorption effect makes the two interconnected on the nerve cell membrane, and jointly promotes the development and function of nerve cells. At the same time, DHA can improve the fluidity of the cerebral cortex cell membrane and improve the quality of nerve signal transmission; while phosphatidylserine can ensure the smooth flow of the nerve conduction pathway and promote the release and transmission of neurotransmitters. The synergistic effect of the two can significantly improve the efficiency of nerve transmission, thereby contributing to the improvement of neural development.

[0068] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims

1. A food composition for promoting neural development, characterized in that: The invention comprises the following raw materials in parts by weight: 20-30 parts of whey protein powder, 10-20 parts of DHA algae oil powder, 15-20 parts of walnut powder, 10-15 parts of oatmeal powder, 0.5-1.0 parts of choline, 0.1-0.3 parts of Hericium erinaceus extract, 1-2 parts of soursop polysaccharide, 0.1-0.3 parts of vitamin C, 0.2-0.4 parts of vitamin B complex, 0.2-0.5 parts of folic acid, 1.0-1.5 parts of phosphatidylserine, 0.5-1.0 parts of taurine and 0.05-0.10 parts of complex trace elements.

2. A food composition for promoting neural development as claimed in claim 1, characterized in that: It includes the following raw materials in parts by weight: 25 parts of whey protein powder, 15 parts of DHA algae oil powder, 18 parts of walnut powder, 12 parts of oatmeal powder, 0.7 parts of choline, 0.2 parts of Hericium erinaceus extract, 1.5 parts of soursop polysaccharide, 0.2 parts of vitamin C, 0.3 parts of vitamin B complex, 0.35 parts of folic acid, 1.3 parts of phosphatidylserine, 0.75 parts of taurine, and 0.08 parts of complex trace elements.

3. A food composition for promoting neural development as claimed in claim 1, characterized in that: The Hericium erinaceus extract is obtained by the following method: using a pulverizer to grind dried Hericium erinaceus fruiting bodies to obtain Hericium erinaceus powder, adding purified water to the Hericium erinaceus powder for extraction, wherein the amount of water added for the first time is 6-10 times the weight of the Hericium erinaceus powder, and the extraction time is 2-4 hours; the amount of water added for the second time is 8-12 times the weight of the Hericium erinaceus powder, and the extraction time is 1.5-2.5 hours; after the extraction is completed, filtering is performed, and the filtrate is taken and concentrated under reduced pressure to 30-50% of the volume of the original solution; the concentrated filtrate is extracted with water-saturated n-butanol, the volume ratio of the filtrate to n-butanol is 1:1-3, and extraction is performed 2 to 4 times; after the extraction is completed, the n-butanol extraction layer is decompressed to recover the solvent to obtain an extract; the extract is dried at 60-70° C., and then pulverized to obtain the Hericium erinaceus extract.

4. A food composition for promoting neural development as claimed in claim 3, characterized in that: The extraction is carried out in a water bath under heating conditions, and the heating temperature is 85-100°C.

5. A food composition for promoting neural development as claimed in claim 1, characterized in that: The soursop polysaccharide is obtained by the following method: peeling and core-removing soursop fruits, taking the pulp part, crushing the pulp into pulp with a pulper to obtain pulp pulp, soaking the pulp pulp with ethanol, filtering out the ethanol after soaking, and taking the pulp pulp; drying the treated pulp pulp at 55-65° C., then crushing it with a crusher, adding distilled water to the pulp pulp at a solid-liquid ratio of 1:5-10, adjusting the pH value to neutral, placing it in a water bath for heating extraction, controlling the temperature at 75-85° C., and extracting for 2-4 hours; filtering and taking the filtrate after the extraction, vacuum concentrating the filtrate to 20-30% of the volume of the original solution, adding a chloroform-n-butanol mixed solution to the concentrated filtrate, shaking at room temperature for 15-25 minutes, and then evaporating at 25 00-3500rpm centrifugation for 15-25min, filtering to remove protein precipitate; repeating this step 3-5 times, the volume ratio of the concentrated filtrate to the chloroform-n-butanol mixed solution is 1:3-4, and the chloroform-n-butanol mixed solution consists of chloroform and n-butanol in a volume ratio of 4-5:1; adding 95wt% edible alcohol to the filtrate after protein removal, the edible alcohol added in an amount of 40-60% of the volume of the filtrate, standing at 4-6°C for 10-12h, then centrifuging at 4000-6000rpm for 10-20min, filtering and collecting the precipitate, washing with 80wt% ethanol 2-3 times, and then drying the precipitate at 55-65°C to constant weight, so as to obtain soursop polysaccharide.

6. A food composition for promoting neural development as claimed in claim 5, characterized in that The soaking with ethanol is specifically as follows: soaking the pulp slurry with 95wt% ethanol, the volume ratio of the pulp slurry to the ethanol is 1:2-4, and the soaking condition is soaking at 40-50°C for 10-15h.

7. A food composition for promoting neural development as claimed in claim 1, characterized in that: The vitamin B complex consists of B1, B6 and B12 in a mass ratio of (8-12):(4-7):(2-5).

8. A food composition for promoting neural development as claimed in claim 1, characterized in that: The composite trace elements are composed of zinc, iron, copper and selenium in a mass ratio of (2.0-4.0):(2.0-3.5):(1.0-1.8):(0.5-0.9).

9. A process for preparing a food composition for promoting neural development according to any one of claims 1 to 9, characterized in that: The following steps are involved: S1, weigh the raw materials by weight and set aside; S2, adding whey protein powder, DHA algae oil powder, walnut powder and oatmeal powder into a blender for preliminary mixing to obtain mixture I; S3, gradually adding choline, Hericium erinaceus extract, soursop polysaccharide, vitamin C, vitamin B complex, folic acid, phosphatidylserine, taurine and complex trace elements to mixed material I, stirring while adding, to obtain mixed material II; S4. Place the mixture II into a dryer for drying to obtain a food composition for promoting nerve development.

10. The preparation process of a food composition for promoting neural development according to claim 9, characterized in that: The initial stirring speed in S2 is 100-200 rpm, and the stirring time is 10-15 min; the stirring speed while adding in S3 is 800-1200 rpm, and the stirring time is 5-10 min; the drying temperature in S4 is 40-60° C., and the drying time is 2-4 h.

Images