Preparation method of beverage capable of rapidly dispelling effects of alcohol and protecting liver

Abstract

The invention belongs to the field of hangover alleviating and liver protecting products, and particularly discloses a preparation method of a quick hangover alleviating and liver protecting drink, the drink is prepared by compounding a chamomile extract and a plurality of plant raw materials (dandelion, fingered citron, hovenia acerba and the like), and the chamomile extract is extracted by a special process. The preparation method comprises the following steps: firstly, soaking and cooking part of the raw materials, and then crushing, soaking and extracting the other part of the raw materials; mixing the liquids obtained in the steps, adding the rest raw materials, soaking, extracting and mixing; and finally, adding the chamomile extract, uniformly mixing, pasteurizing and canning. The beverage adopts fresh plant raw materials, pressure and temperature control is emphasized in the preparation process, and the quality and the effect are ensured. The process is simple, efficient and suitable for industrial production, the prepared beverage has remarkable sobering-up and liver-protecting effects, and the healthy and effective sobering-up and liver-protecting beverage can be obtained by people.

Description

Technical Field

[0001] The invention belongs to the field of alcohol sobering products, and specifically discloses a preparation method of a quick alcohol sobering and liver protecting drink. Background Art

[0002] In today's market, there are many types of hangover relieving products, but if you look closely at these products, it is not difficult to find that most of them focus on the single function of hydration and diuresis, trying to accelerate the metabolism of alcohol in the body by increasing urine discharge. This orientation not only limits the diversified utility of products, but also fails to fully meet consumers' demand for diversified and efficient hangover relieving products. Many products rely too much on edible chemical ingredients as compound additives. Although these ingredients can assist in hangover relieving to a certain extent, their added amount often accounts for a large proportion, resulting in the weakening of the natural properties of the product and a strong sense of artificial synthesis in taste, which is difficult to win the widespread favor of consumers.

[0003] More importantly, although the use of these chemical ingredients may bring a certain hangover-relieving effect in the short term, long-term and frequent intake may have potential effects on physical health, which runs counter to the modern people's pursuit of a healthy life. Therefore, the market urgently needs a new type of hangover-relieving product that can effectively relieve hangovers while also being healthy, natural, and having a good taste.

[0004] Although there are some hangover-relieving drinks made from Chinese herbal medicines on the market, attempting to achieve the purpose of hangover-relieving and liver-protecting through the natural power of Chinese herbal medicines, the preparation process of these products is often rough, lacking refined processing and technological innovation. In terms of taste and flavor, these products often do not meet more stringent technical requirements, resulting in a strong mixed smell of medicinal properties and a poor taste, which is difficult to be accepted by the majority of consumers. Producers often use the traditional concept of "good medicine tastes bitter" to cover up their technical deficiencies, ignoring the importance of product taste for consumer choice.

[0005] In addition, the actual drinking effect of these Chinese herbal alcohol-relieving beverages is not ideal. On the one hand, due to the limitations of the preparation process, the effective ingredients of the Chinese herbal medicines may not be fully extracted and utilized, resulting in a significant reduction in the alcohol-relieving effect of the product; on the other hand, there may be unreasonable aspects in the compatibility and dosage control of the Chinese herbal medicines, which affects the overall effect of the product. Summary of the invention

[0006] In view of the problems existing in the hangover sobering products on the current market, the present invention proposes a new fast sobering and liver-protecting drink and its preparation method. The drink not only uses a variety of natural Chinese herbal medicines as raw materials, but also fully extracts and utilizes the effective ingredients of Chinese herbal medicines through a refined preparation process, and also achieves the diversified efficacy and excellent taste of the product through scientific compatibility and dosage control. At the same time, the preparation method of the drink is simple and efficient, suitable for industrial production, and is expected to bring a healthy, natural, and excellent-tasting new hangover sobering product to the market.

[0007] The purpose of the present invention is achieved through the following technical solutions.

[0008] A quick hangover sobering and liver-protecting drink, prepared by compounding chamomile extract, dandelion, bergamot, tangerine peel, peach kernel, cassia seed, amomum, purslane, polygonatum, gardenia, kudzu root, larix raphanii, mulberry, roselle, hawthorn, hemp seed, orange peel and water

[0009] Furthermore, the above-mentioned quick sobering and liver protecting drink is prepared by compounding, by weight, 1-3 parts of chamomile extract, 15-25 parts of dandelion, 3-10 parts of bergamot, 1-5 parts of bitter orange, 1-5 parts of peach kernel, 3-8 parts of cassia seed, 3-8 parts of amomum, 4-8 parts of portulaca, 6-10 parts of polygonatum, 4-8 parts of gardenia, 4-8 parts of kudzu root, 2-4 parts of larix sabdariffa, 4-8 parts of mulberry, 3-8 parts of roselle, 4-8 parts of hawthorn, 3-8 parts of hemp seed, 3-8 parts of tangerine peel and an appropriate amount of water.

[0010] Furthermore, the above-mentioned quick sobering and liver protecting drink is prepared by compounding, by weight, 2 parts of chamomile extract, 20 parts of dandelion, 6 parts of bergamot, 3 parts of Citrus aurantium, 3 parts of peach kernel, 5 parts of cassia seed, 5 parts of Amomum villosum, 6 parts of Portulaca oleifera, 8 parts of Polygonatum odoratum, 6 parts of Gardenia jasminoides, 6 parts of Pueraria root, 3 parts of Leucanthemum officinale, 6 parts of mulberry, 5 parts of Roselle, 6 parts of Hawthorn, 5 parts of Cannabis seed, 5 parts of tangerine peel and an appropriate amount of water.

[0011] Furthermore, in the above-mentioned quick hangover sobering and liver protecting drink, the raw materials except chamomile extract and water are all fresh plant raw materials.

[0012] Furthermore, in the above-mentioned quick sobering and liver-protecting drink, the chamomile extract is prepared by the following steps:

[0013] S1. Raw material preparation

[0014] S1.1 Select fresh, pest-free chamomile as raw material.

[0015] S1.2 Wash the chamomile raw materials and remove impurities.

[0016] S1.3 Use a juicer or blender to crush the chamomile into fine particles.

[0017] S2. Soaking in ethanol water solution

[0018] S2.1 Mix the crushed chamomile particles with an equal mass of 50-65% ethanol aqueous solution;

[0019] S2.2 Soak for 30-50 minutes;

[0020] S3. Ultrasonic assisted extraction

[0021] S3.1 During the soaking process, the mixture is ultrasonically treated using an ultrasonic device with the frequency set to 40 kHz;

[0022] S3.2 Processing time 10-20min;

[0023] S4. Centrifugal separation

[0024] S4.1 Place the soaked chamomile liquid into a centrifuge;

[0025] S4.2 Centrifuge at 1000-1500 r / min for 10-15 min;

[0026] S5. Distillation and concentration

[0027] S5.1 distill the centrifuged liquid at 0.5-0.9 standard atmospheric pressure and 85-90°C, remove the effluent, and collect the remaining liquid to obtain a primary extract;

[0028] S5.2 Filter the extract using a 300-400 mesh sieve.

[0029] S5.3 Add 30-45 times the mass of 75-80% ethanol solution to the filtrate and mix well;

[0030] S5.4 distilling again at 0.8-1.0 standard atmospheric pressure and 90-100° C., removing the effluent, and obtaining chamomile essential oil;

[0031] S6 Supercritical Carbon Dioxide Extraction

[0032] S6.1 Add the distilled and concentrated chamomile essential oil into the extraction kettle:

[0033] Supercritical carbon dioxide fluid is introduced for continuous cycle extraction. At this stage, the following parameters need to be controlled:

[0034] Extraction kettle temperature: controlled between 30-45°C;

[0035] Extraction pressure: set at 15-25MPa, so that carbon dioxide is in a supercritical state;

[0036] Carbon dioxide flow rate: 15-20kg / h;

[0037] Extraction time: The extraction time is set to 1.5-2.5h;

[0038] S6.2 Separation

[0039] After the extraction is completed, the carbon dioxide fluid containing chamomile components is introduced into the separator for separation. In the separator, the pressure and temperature are adjusted to restore the carbon dioxide to a gaseous state, and the extract is released from the bottom of the separator. After the extract is allowed to stand, the oil and water are separated to obtain chamomile essential oil with higher purity, which is the chamomile extract.

[0040] Furthermore, the above-mentioned quick sobering and liver-protecting drink is a medicine or food.

[0041] The present invention also discloses a method for preparing the above-mentioned quick sobering up and liver protecting drink, comprising the following steps:

[0042] Step 1: Soak kudzu root, roselle and gardenia in water, heat to 115-125℃ and steam for 20-40 minutes. Cool and set aside;

[0043] Step 2: Crush bergamot, polygonatum, tangerine peel and amomum villosum, add larix raphanii, soak in water for 120-240 minutes, heat and extract, filter, and set aside the filtrate;

[0044] Step 3: Wash dandelion, purslane, hawthorn and mulberry, soak them in water for 120-240 minutes, heat and extract, filter and set aside the filtrate;

[0045] Step 4, mix the liquids from steps 1, 2, and 3 and set aside;

[0046] Step 5, soaking Cassia seed, Citrus aurantium, hemp seed and peach kernel in water for 120-240 minutes, heating and extracting, filtering and setting aside the filtrate;

[0047] Step 6: Add the liquid obtained in steps 4 and 5 to the chamomile extract and mix well. Then pasteurize and can.

[0048] Furthermore, in the preparation method of the above-mentioned quick sobering and liver-protecting drink, in the step 1, the pressurized pressure is not less than 0.2Mpa, and the cooking time is 30 minutes.

[0049] Furthermore, in the preparation method of the above-mentioned quick sobering and liver-protecting drink, in the step 6, the sterilization temperature does not exceed 90°C.

[0050] The invention also discloses use of the quick sobering up and liver protecting drink in preparing quick sobering up and liver protecting medicines.

[0051] Compared with the existing technology, the present invention has the following advantages and beneficial effects:

[0052] The present invention has carefully created a fast sobering and liver-protecting drink and a unique preparation process thereof. The drink not only combines the excellent efficacy of a variety of selected natural plant raw materials, but also strives for excellence in preparation details, thereby ensuring the product's high efficiency, safety and natural health attributes, providing an ideal sobering solution for modern consumers who pursue a healthy life.

[0053] In terms of raw material selection, the drink carefully mixes a variety of natural plant raw materials with alcohol sobering and liver protection effects, such as chamomile extract, dandelion, bergamot, citrus aurantium, peach kernel, cassia seed, amomum, portulaca, polygonatum, gardenia, kudzu root, larix raphanii, mulberry, roselle, hawthorn, hemp seed, tangerine peel, etc. These raw materials can work synergistically through scientific compatibility, quickly decompose alcohol, reduce the burden on the liver, and provide rich nutrients, which help repair damaged liver cells and promote liver health.

[0054] It is particularly worth mentioning that the chamomile extract in the drink is prepared using a special process. Through multiple fine steps such as raw material preparation, ethanol-water solution soaking, ultrasonic-assisted extraction, centrifugal separation, distillation concentration, and supercritical carbon dioxide extraction, the effective ingredients in chamomile are successfully extracted, which not only improves the extraction efficiency, but also ensures the purity and activity of the extract, laying a solid foundation for the drink's alcohol-relief and liver-protection effects.

[0055] In terms of preparation technology, the invention also pays attention to details and scientificity. Through pressure cooking, fine extraction and scientific mixing technology, the effective ingredients in the raw materials are fully extracted, while maintaining the excellent taste and natural color of the beverage. In addition, the sterilization temperature and time are strictly controlled during the preparation process, which not only ensures the safety and stability of the product, but also avoids the destruction of the nutritional components of the beverage by high temperature, ensuring the quality and effect of the beverage.

[0056] In summary, the fast sobering and liver-protecting drink and its preparation method provided by the present invention not only integrate the excellent effects of multiple natural plant raw materials, but also strive for excellence in preparation details, achieving the remarkable effects of efficient sobering and protecting the liver. The drink has a refreshing taste, is natural and healthy, and is an ideal choice for modern consumers who pursue a healthy life. At the same time, the invention also provides new ideas and new directions for the research and development of sobering products, and has broad market prospects and medicinal value. BRIEF DESCRIPTION OF THE DRAWINGS

[0057] Figure 1 Comparison of intoxication duration in mice;

[0058] Figure 2 Comparison of sleep duration in mice;

[0059] Figure 3 Comparison of attachment time in mice. DETAILED DESCRIPTION

[0060] A quick hangover sobering and liver-protecting drink, which is prepared by compounding, by weight, 1-3 parts of chamomile extract, 15-25 parts of dandelion, 3-10 parts of bergamot, 1-5 parts of Citrus aurantium, 1-5 parts of peach kernel, 3-8 parts of cassia seed, 3-8 parts of Amomum villosum, 4-8 parts of Portulaca oleracea, 6-10 parts of Polygonatum odoratum, 4-8 parts of Gardenia jasminoides, 4-8 parts of Pueraria root, 2-4 parts of Leucanthemum officinale, 4-8 parts of mulberry, 3-8 parts of roselle, 4-8 parts of hawthorn, 3-8 parts of hemp seed, 3-8 parts of tangerine peel and an appropriate amount of water;

[0061] All ingredients except chamomile extract and water are fresh plant materials;

[0062] The method for preparing the above-mentioned quick hangover sobering and liver protecting beverage comprises the following steps:

[0063] Step 1: Soak kudzu root, roselle and gardenia in water, pressurize to 0.2Mpa, heat to 115-125℃ and cook, keep warm for 20-40min, cool and set aside;

[0064] Step 2: Crush bergamot, polygonatum, tangerine peel and amomum villosum, add larix raphanii, soak in water for 120-240 minutes, heat and extract, filter, and set aside the filtrate;

[0065] Step 3: Wash dandelion, purslane, hawthorn and mulberry, soak them in water for 120-240 minutes, heat and extract, filter and set aside the filtrate;

[0066] Step 4, mix the liquids from steps 1, 2, and 3 and set aside;

[0067] Step 5, soaking Cassia seed, Citrus aurantium, hemp seed and peach kernel in water for 120-240 minutes, heating and extracting, filtering and setting aside the filtrate;

[0068] Step 6: Add the liquid obtained in steps 4 and 5 to the chamomile extract and mix well. Evaporate at 40-50°C to a density of 1.03-1.08 g / mL. Pasteurize at a temperature not exceeding 90°C and can.

[0069] In order to make the purpose, technical scheme and advantages of the present invention clearer, the present invention is further described in detail below through the accompanying drawings and embodiments. However, it should be understood that the specific embodiments described herein are only used to explain the present invention and are not intended to limit the scope of the present invention. In addition, in the following description, the description of known structures and technologies is omitted to avoid unnecessary confusion of the concept of the present invention.

[0070] It should be noted that, in the absence of conflict, the embodiments and features in the embodiments of the present application can be combined with each other. The present invention will be described in detail below in conjunction with the embodiments.

[0071] The chamomile extract in Examples 1-3 is common chamomile extract purchased from Shanyang Lianfeng Biotechnology Co., Ltd.

[0072] Example 1

[0073] A quick hangover sobering and liver-protecting drink, calculated by weight, is prepared by compounding 1 part of chamomile extract, 15 parts of dandelion, 3 parts of bergamot, 1 part of Citrus aurantium, 1 part of peach kernel, 3 parts of cassia seed, 3 parts of Amomum villosum, 4 parts of Portulaca oleracea, 6 parts of Polygonatum odoratum, 4 parts of Gardenia jasminoides, 4 parts of Pueraria root, 2 parts of Leucanthemum officinale, 4 parts of mulberry, 3 parts of Roselle, 4 parts of Hawthorn, 3 parts of Cannabis seed, 3 parts of Tangerine peel and an appropriate amount of water;

[0074] All ingredients except chamomile extract and water are fresh plant materials;

[0075] The method for preparing the above-mentioned quick hangover sobering and liver protecting beverage comprises the following steps:

[0076] Step 1: Soak kudzu root, roselle and gardenia in water, pressurize to 0.2Mpa, heat to 115℃ and cook, keep warm for 40min, cool and set aside;

[0077] Step 2: Crush bergamot, polygonatum, tangerine peel and amomum villosum, add larix raphanii, soak in water for 120-240 minutes, heat and extract, filter, and set aside the filtrate;

[0078] Step 3: Wash dandelion, purslane, hawthorn and mulberry, soak them in water for 120-240 minutes, heat and extract, filter and set aside the filtrate;

[0079] Step 4, mix the liquids from steps 1, 2, and 3 and set aside;

[0080] Step 5, soaking Cassia seed, Citrus aurantium, hemp seed and peach kernel in water for 120-240 minutes, heating and extracting, filtering and setting aside the filtrate;

[0081] Step 6: Add the liquid obtained in steps 4 and 5 to the chamomile extract and mix well. Evaporate at 40-50℃ to a density of 1.05g / mL. Then pasteurize at a temperature not exceeding 90℃ and can.

[0082] Example 2

[0083] A quick hangover sobering and liver-protecting drink, calculated by weight, is prepared by compounding 2 parts of chamomile extract, 20 parts of dandelion, 6 parts of bergamot, 3 parts of Citrus aurantium, 3 parts of peach kernel, 5 parts of cassia seed, 5 parts of Amomum villosum, 6 parts of Portulaca oleracea, 8 parts of Polygonatum odoratum, 6 parts of Gardenia jasminoides, 6 parts of Pueraria root, 3 parts of Leucanthemum officinale, 6 parts of mulberry, 5 parts of Roselle, 6 parts of Hawthorn, 5 parts of Cannabis seed, 5 parts of Tangerine peel and an appropriate amount of water;

[0084] All ingredients except chamomile extract and water are fresh plant materials;

[0085] The method for preparing the above-mentioned quick hangover sobering and liver protecting beverage comprises the following steps:

[0086] Step 1: Soak kudzu root, roselle and gardenia in water, pressurize to 0.2Mpa, heat to 120℃ and cook, keep warm for 30min, cool and set aside;

[0087] Step 2: Crush bergamot, polygonatum, tangerine peel and amomum villosum, add larix raphanii, soak in water for 120-240 minutes, heat and extract, filter, and set aside the filtrate;

[0088] Step 3: Wash dandelion, purslane, hawthorn and mulberry, soak them in water for 120-240 minutes, heat and extract, filter and set aside the filtrate;

[0089] Step 4, mix the liquids from steps 1, 2, and 3 and set aside;

[0090] Step 5, soaking Cassia seed, Citrus aurantium, hemp seed and peach kernel in water for 120-240 minutes, heating and extracting, filtering and setting aside the filtrate;

[0091] Step 6: Add the liquid obtained in steps 4 and 5 to the chamomile extract and mix well. Evaporate at 40-50℃ to a density of 1.05g / mL. Then pasteurize at a temperature not exceeding 90℃ and can.

[0092] Example 3

[0093] A quick hangover sobering and liver-protecting drink, calculated by weight, is prepared by compounding 3 parts of chamomile extract, 25 parts of dandelion, 10 parts of bergamot, 5 parts of Citrus aurantium, 5 parts of peach kernel, 8 parts of cassia seed, 8 parts of Amomum villosum, 8 parts of Portulaca oleracea, 10 parts of Polygonatum odoratum, 8 parts of Gardenia jasminoides, 8 parts of Pueraria root, 4 parts of Leucanthemum officinale, 8 parts of mulberry, 8 parts of Roselle, 8 parts of Hawthorn, 8 parts of Cannabis seed, 8 parts of Tangerine peel and an appropriate amount of water;

[0094] All ingredients except chamomile extract and water are fresh plant materials;

[0095] The method for preparing the above-mentioned quick hangover sobering and liver protecting beverage comprises the following steps:

[0096] Step 1: Soak kudzu root, roselle and gardenia in water, pressurize to 0.2Mpa, heat to 125℃ and cook, keep warm for 20min, cool and set aside;

[0097] Step 2: Crush bergamot, polygonatum, tangerine peel and amomum villosum, add larix raphanii, soak in water for 120-240 minutes, heat and extract, filter, and set aside the filtrate;

[0098] Step 3: Wash dandelion, purslane, hawthorn and mulberry, soak them in water for 120-240 minutes, heat and extract, filter and set aside the filtrate;

[0099] Step 4, mix the liquids from steps 1, 2, and 3 and set aside;

[0100] Step 5, soaking Cassia seed, Citrus aurantium, hemp seed and peach kernel in water for 120-240 minutes, heating and extracting, filtering and setting aside the filtrate;

[0101] Step 6: Add the liquid obtained in steps 4 and 5 to the chamomile extract and mix well. Evaporate at 40-50℃ to a density of 1.05g / mL. Then pasteurize at a temperature not exceeding 90℃ and can.

[0102] Example 4

[0103] A quick hangover sobering and liver-protecting drink, calculated by weight, is prepared by compounding 2 parts of chamomile extract, 20 parts of dandelion, 6 parts of bergamot, 3 parts of Citrus aurantium, 3 parts of peach kernel, 5 parts of cassia seed, 5 parts of Amomum villosum, 6 parts of Portulaca oleracea, 8 parts of Polygonatum odoratum, 6 parts of Gardenia jasminoides, 6 parts of Pueraria root, 3 parts of Leucanthemum officinale, 6 parts of mulberry, 5 parts of Roselle, 6 parts of Hawthorn, 5 parts of Cannabis seed, 5 parts of Tangerine peel and an appropriate amount of water;

[0104] All ingredients except chamomile extract and water are fresh plant materials;

[0105] The chamomile extract is prepared by the following steps:

[0106] S1. Raw material preparation

[0107] S1.1 Select fresh, pest-free chamomile as raw material.

[0108] S1.2 Wash the chamomile raw materials and remove impurities.

[0109] S1.3 Use a juicer or blender to crush the chamomile into fine particles.

[0110] S2. Soaking in ethanol water solution

[0111] S2.1 Mix the crushed chamomile particles with an equal mass of 60% ethanol aqueous solution;

[0112] S2.2 Soak for 40 minutes;

[0113] S3. Ultrasonic assisted extraction

[0114] S3.1 During the soaking process, the mixture is ultrasonically treated using an ultrasonic device with the frequency set to 40 kHz;

[0115] S3.2 Processing time 15min;

[0116] S4. Centrifugal separation

[0117] S4.1 Place the soaked chamomile liquid into a centrifuge;

[0118] S4.2 Centrifuge at 1250 r / min for 15 min;

[0119] S5. Distillation and concentration

[0120] S5.1 distill the centrifuged liquid at 0.8 standard atmospheric pressure and 85-90°C, remove the effluent, collect the remaining liquid, and obtain a primary extract;

[0121] S5.2 Filter the extract using a 300-400 mesh sieve.

[0122] S5.3 Add 40 times the mass of 75-80% ethanol solution to the filtrate and mix well;

[0123] S5.4 distill again at 0.9 standard atmospheric pressure and 95°C, remove the effluent, and obtain chamomile essential oil;

[0124] S6 Supercritical Carbon Dioxide Extraction

[0125] S6.1 Add the distilled and concentrated chamomile essential oil into the extraction kettle:

[0126] Supercritical carbon dioxide fluid is introduced for continuous cycle extraction. At this stage, the following parameters need to be controlled:

[0127] Extraction kettle temperature: controlled between 30-45°C;

[0128] Extraction pressure: set at 20MPa, so that carbon dioxide is in a supercritical state;

[0129] Carbon dioxide flow rate: 18kg / h;

[0130] Extraction time: The extraction time was set to 2.0h;

[0131] S6.2 Separation

[0132] After the extraction is completed, the carbon dioxide fluid containing chamomile components is introduced into the separator for separation. In the separator, the pressure and temperature are adjusted to restore the carbon dioxide to a gaseous state, and the extract is released from the bottom of the separator. After the extract is allowed to stand, the oil and water are separated to obtain chamomile essential oil with higher purity, which is the chamomile extract.

[0133] The method for preparing the above-mentioned quick hangover sobering and liver protecting beverage comprises the following steps:

[0134] Step 1: Soak kudzu root, roselle and gardenia in water, pressurize to 0.2Mpa, heat to 120℃ and cook, keep warm for 30min, cool and set aside;

[0135] Step 2: Crush bergamot, polygonatum, tangerine peel and amomum villosum, add larix raphanii, soak in water for 120-240 minutes, heat and extract, filter, and set aside the filtrate;

[0136] Step 3: Wash dandelion, purslane, hawthorn and mulberry, soak them in water for 120-240 minutes, heat and extract, filter and set aside the filtrate;

[0137] Step 4, mix the liquids from steps 1, 2, and 3 and set aside;

[0138] Step 5, soaking Cassia seed, Citrus aurantium, hemp seed and peach kernel in water for 120-240 minutes, heating and extracting, filtering and setting aside the filtrate;

[0139] Step 6: Add the liquid obtained in steps 4 and 5 to the chamomile extract and mix well. Evaporate at 40-50℃ to a density of 1.05g / mL. Then pasteurize at a temperature not exceeding 90℃ and can.

[0140] Comparative Example 1

[0141] A quick hangover sobering and liver-protecting drink, calculated by weight, is prepared by compounding 20 parts of dandelion, 6 parts of bergamot, 3 parts of Citrus aurantium, 3 parts of peach kernel, 5 parts of cassia seed, 5 parts of Amomum villosum, 6 parts of Portulaca oleracea, 8 parts of Polygonatum odoratum, 6 parts of Gardenia jasminoides, 6 parts of Pueraria root, 3 parts of Leucanthemum officinale, 6 parts of mulberry, 5 parts of Roselle, 6 parts of Hawthorn, 5 parts of Cannabis seed, 5 parts of Tangerine peel and an appropriate amount of water;

[0142] The raw materials are all fresh plant materials;

[0143] The method for preparing the above-mentioned quick hangover sobering and liver protecting beverage comprises the following steps:

[0144] Step 1: Soak kudzu root, roselle and gardenia in water, pressurize to 0.2Mpa, heat to 120℃ and cook, keep warm for 30min, cool and set aside;

[0145] Step 2: Crush bergamot, polygonatum, tangerine peel and amomum villosum, add larix raphanii, soak in water for 120-240 minutes, heat and extract, filter, and set aside the filtrate;

[0146] Step 3: Wash dandelion, purslane, hawthorn and mulberry, soak them in water for 120-240 minutes, heat and extract, filter and set aside the filtrate;

[0147] Step 4, mix the liquids from steps 1, 2, and 3 and set aside;

[0148] Step 5, soaking Cassia seed, Citrus aurantium, hemp seed and peach kernel in water for 120-240 minutes, heating and extracting, filtering and setting aside the filtrate;

[0149] Step 6: Mix the liquids obtained in steps 4 and 5 evenly, evaporate at 40-50°C to a density of 1.05 g / mL, then pasteurize at a temperature not exceeding 90°C and can.

[0150] This comparative example does not contain chamomile extract, and the rest is the same as Example 2.

[0151] Comparative Example 2

[0152] A quick sobering and liver-protecting drink, calculated by weight, is prepared by compounding 2 parts of chamomile extract, 3 parts of peach kernel, 5 parts of cassia seed, 5 parts of amomum villosum, 6 parts of purslane, 8 parts of polygonatum, 6 parts of gardenia, 6 parts of kudzu root, 3 parts of larix raphani, 6 parts of mulberry, 5 parts of roselle, 6 parts of hawthorn, 5 parts of hemp seed, 5 parts of tangerine peel and an appropriate amount of water;

[0153] All ingredients except chamomile extract and water are fresh plant materials;

[0154] The method for preparing the above-mentioned quick hangover sobering and liver protecting beverage comprises the following steps:

[0155] Step 1: Soak kudzu root, roselle and gardenia in water, pressurize to 0.2Mpa, heat to 120℃ and cook, keep warm for 30min, cool and set aside;

[0156] Step 2: Grind polygonatum odoratum, tangerine peel and amomum villosum, add larix raphanii, soak in water for 120-240 minutes, heat and extract, filter, and set aside the filtrate;

[0157] Step 3: Wash purslane, hawthorn and mulberry, soak them in water for 120-240 minutes, heat and extract, filter and set aside the filtrate;

[0158] Step 4, mix the liquids from steps 1, 2, and 3 and set aside;

[0159] Step 5, soaking Cassia seed, hemp seed and peach kernel in water for 120-240 minutes, heating and extracting, filtering and setting aside the filtrate;

[0160] Step 6: Add the liquid obtained in steps 4 and 5 to the chamomile extract and mix well. Evaporate at 40-50℃ to a density of 1.05g / mL. Then pasteurize at a temperature not exceeding 90℃ and can.

[0161] This comparative example does not contain dandelion, citron, and trifoliate orange, and the rest is the same as Example 2.

[0162] Comparative Example 3

[0163] A quick sobering and liver-protecting drink, which is prepared by mixing, by weight, 3 parts of peach kernel, 5 parts of cassia seed, 5 parts of amomum villosum, 6 parts of purslane, 8 parts of polygonatum, 6 parts of gardenia, 6 parts of kudzu root, 3 parts of larix raphani, 6 parts of mulberry, 5 parts of roselle, 6 parts of hawthorn, 5 parts of hemp seed, 5 parts of tangerine peel and an appropriate amount of water;

[0164] All ingredients except chamomile extract and water are fresh plant materials;

[0165] The method for preparing the above-mentioned quick hangover sobering and liver protecting beverage comprises the following steps:

[0166] Step 1: Soak kudzu root, roselle and gardenia in water, pressurize to 0.2Mpa, heat to 120℃ and cook, keep warm for 30min, cool and set aside;

[0167] Step 2: Grind polygonatum odoratum, tangerine peel and amomum villosum, add larix raphanii, soak in water for 120-240 minutes, heat and extract, filter, and set aside the filtrate;

[0168] Step 3: Wash purslane, hawthorn and mulberry, soak them in water for 120-240 minutes, heat and extract, filter and set aside the filtrate;

[0169] Step 4, mix the liquids from steps 1, 2, and 3 and set aside;

[0170] Step 5, soaking Cassia seed, hemp seed and peach kernel in water for 120-240 minutes, heating and extracting, filtering and setting aside the filtrate;

[0171] Step 6: Mix the liquids obtained in steps 4 and 5 evenly, evaporate at 40-50°C to a density of 1.05 g / mL, then pasteurize at a temperature not exceeding 90°C and can.

[0172] This comparative example does not contain chamomile extract, dandelion, bergamot, and bitter orange, and the rest is the same as Example 2.

[0173] Positive control example

[0174] Guangda is a reliable alcohol-relieving oral liquid.

[0175] Test Case

[0176] (1) 100 Kunming mice were randomly divided into 5 groups, with 20 mice in each group. The mice were gavaged with 52% liquor at a dose of 15, 17.5, 20, 22.5, and 25 ml / kg, respectively. The mice were observed for drunkenness and death 2 hours later. The mice were gently placed in the cage with their backs facing down. If the mice maintained the back-down posture for more than 30 seconds, the righting reflex was considered to be lost, i.e., drunkenness. The test results are shown in Table 1:

[0177] Table 1: Drunkenness

[0178] Input quantity Number of non-intoxicated Number of drunkenness Number of deaths 15ml / kg 20 6 14 0 17.5ml / kg 20 4 16 0 20ml / kg 20 0 20 0 22.5ml / kg 20 0 20 1 25ml / kg 20 0 20 2

[0179] From the results in Table 1, 20 ml / kg was selected as the subsequent experimental dose.

[0180] (2) Experimental Kunming mice were raised in the laboratory for 5 days, fasted for 12 hours, and randomly divided into negative control group, Guangda Credible Alcohol Relief Oral Liquid (positive control group), and experimental group (Example 1-4, Comparative Example 1-3), with 20 mice in each group. All mice were given 20 ml / kg of experimental liquor by gavage, and then the negative control group mice were given 10 ml / kg of distilled water by gavage; the positive control group was given 10 ml / kg of Guangda Credible Alcohol Relief Oral Liquid by gavage; and the experimental group was given 10 ml / kg of beverage by gavage.

[0181] The time from the time of liquor gavage was counted, and the time when the righting reflex of the mouse disappeared was recorded as the drunkenness time; the time from the disappearance of the righting reflex of the mouse to the recovery of the righting reflex was the sleep duration; after the righting reflex was recovered, the mouse was placed on a vertical metal net, and the end point was when the mouse fell off the metal net, which was the time when the mouse was attached to the metal net. The drunkenness time, sleep duration and attachment time of the mice are shown in Table 2 and Figure 1-3 (average value).

[0182] Table 2 Data on drunkenness time, sleep duration and clinging time of mice

[0183] Group Drunk time (min) Sleep duration (min) Climbing time(s) Negative control group 46.8 282.4 187.2 Positive control group 28.3 228.2 256.4 Example 1 26.1 188.5 276.5 Example 2 25.3 185.6 281.3 Example 3 25.7 187.4 278.6 Example 4 22.3 163.4 311.2 Comparative Example 1 33.5 244.2 234.8 Comparative Example 2 37.9 252.5 243.6 Comparative Example 3 39.2 263.1 223.1

[0184] The above test data show that: compared with the negative control, the sobering and liver-protecting drinks (Examples 1-4) disclosed in the present invention can significantly shorten the drunkenness time (more than 30%), reduce the sleep duration of mice (more than 25%), and greatly increase the clinging time (s) after sobering up (i.e., rapid recovery of physical strength); at the same time, its effect is better than the common sobering drinks on the market (positive control); further analysis of the data of Example 2 and Comparative Examples 1-3 shows that the addition of chamomile extract and dandelion, bergamot, and Citrus aurantium can produce a synergistic effect and improve the sobering effect of this product; further analysis of the data differences between Example 2 and Example 4 shows that the extraction method of chamomile extract disclosed in the present invention has a better and faster sobering effect than purchased ordinary chamomile extract.

[0185] (3) Subjective taste test

[0186] Thirty volunteers conducted a subjective taste test on Example 2, Example 4 and Guangda Credible Alcohol Relief Oral Liquid of the present invention. The results showed that the drinks prepared in Examples 2 and 4 of the present invention had a refreshing taste, less bitter taste of traditional Chinese medicine, a very light taste of traditional Chinese medicine, and an aroma of fresh plants. In particular, the drink prepared in Example 4 had a better taste.

[0187] The above examples show that the present invention proposes a new fast sobering liver-protecting drink and a preparation method thereof. The drink not only uses a variety of natural Chinese herbal medicines as raw materials, fully extracts and utilizes the effective ingredients of Chinese herbal medicines through a refined preparation process, but also achieves the diversified efficacy and excellent taste of the product through scientific compatibility and dosage control. At the same time, the preparation method of the drink is simple and efficient, suitable for industrial production, and is expected to bring a healthy, natural, and excellent-tasting new type of sobering product to the market.

[0188] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention rather than to limit the protection scope of the present invention. Therefore, based on the innovative concept of the present invention, changes and modifications to the embodiments described herein, or equivalent structural or equivalent process transformations made using the contents of the specification and drawings of the present invention, directly or indirectly applying the above technical solutions to other related technical fields are all included in the protection scope of the patent of the present invention.

Claims

1. A quick sobering and liver-protecting drink, characterized in that: The medicine is prepared by compounding chamomile extract, dandelion, bergamot, citrus aurantium, peach kernel, cassia seed, amomum villosum, portulaca oleracea, polygonatum odoratum, gardenia, kudzu root, leucanthemum officinale, mulberry, roselle, hawthorn, hemp seed, tangerine peel and water.

2. A quick sobering and liver-protecting drink, characterized in that: The preparation method is prepared by compounding, by weight, 1-3 parts of chamomile extract, 15-25 parts of dandelion, 3-10 parts of bergamot, 1-5 parts of Citrus aurantium, 1-5 parts of peach kernel, 3-8 parts of cassia seed, 3-8 parts of Amomum villosum, 4-8 parts of Portulaca oleifera, 6-10 parts of Polygonatum odoratum, 4-8 parts of Gardenia jasminoides, 4-8 parts of Pueraria root, 2-4 parts of Leucanthemum officinale, 4-8 parts of mulberry, 3-8 parts of Roselle, 4-8 parts of Hawthorn, 3-8 parts of Cannabis seed, 3-8 parts of Tangerine peel and an appropriate amount of water.

3. A quick sobering and liver-protecting drink, characterized in that: The preparation method is prepared by compounding, by weight, 2 parts of chamomile extract, 20 parts of dandelion, 6 parts of bergamot, 3 parts of Citrus aurantium, 3 parts of peach kernel, 5 parts of cassia seed, 5 parts of Amomum villosum, 6 parts of Portulaca oleracea, 8 parts of Polygonatum odoratum, 6 parts of Gardenia jasminoides, 6 parts of Pueraria root, 3 parts of Leucanthemum officinale, 6 parts of mulberry, 5 parts of Roselle, 6 parts of Hawthorn, 5 parts of Cannabis seed, 5 parts of Tangerine peel and an appropriate amount of water.

4. The quick sobering and liver-protecting drink according to any one of claims 1 to 3, characterized in that: All ingredients except chamomile extract and water are fresh plant materials.

5. The quick sobering and liver-protecting drink according to any one of claims 1 to 3, characterized in that: The chamomile extract is prepared by the following steps: S1. Raw material preparation S1.1 Select fresh, pest-free chamomile as raw material. S1.2 Wash the chamomile raw materials and remove impurities. S1.3 Use a juicer or blender to crush the chamomile into fine particles. S2. Soaking in ethanol water solution S2.1 Mix the crushed chamomile particles with an equal mass of 50-65% ethanol aqueous solution; S2.2 Soak for 30-50 minutes; S3. Ultrasonic assisted extraction S3.1 During the soaking process, the mixture is ultrasonically treated using an ultrasonic device with the frequency set to 40 kHz; S3.2 Processing time 10-20min; S4. Centrifugal separation S4.1 Place the soaked chamomile liquid into a centrifuge; S4.2 Centrifuge at 1000-1500 r / min for 10-15 min; S5. Distillation and concentration S5.1 distill the centrifuged liquid at 0.5-0.9 standard atmospheric pressure and 85-90°C, remove the effluent, and collect the remaining liquid to obtain a primary extract; S5.2 Filter the extract using a 300-400 mesh sieve. S5.3 Add 30-45 times the mass of 75-80% ethanol solution to the filtrate and mix well; S5.4 distilling again at 0.8-1.0 standard atmospheric pressure and 90-100° C., removing the effluent, and obtaining chamomile essential oil; S6 Supercritical Carbon Dioxide Extraction S6.1 Add the distilled and concentrated chamomile essential oil into the extraction kettle: Supercritical carbon dioxide fluid is introduced for continuous cycle extraction. At this stage, the following parameters need to be controlled: Extraction kettle temperature: controlled between 30-45°C; Extraction pressure: set at 15-25MPa, so that carbon dioxide is in a supercritical state; Carbon dioxide flow rate: 15-20kg / h; Extraction time: The extraction time is set to 1.5-2.5h; S6.2 Separation After the extraction is completed, the carbon dioxide fluid containing chamomile components is introduced into the separator for separation. In the separator, the pressure and temperature are adjusted to restore the carbon dioxide to a gaseous state, and the extract is released from the bottom of the separator. After the extract is allowed to stand, the oil and water are separated to obtain chamomile essential oil with higher purity, which is the chamomile extract.

6. The method for preparing the quick sobering up and liver protecting drink according to any one of claims 1 to 3, characterized in that: The following steps are involved: Step 1: Soak kudzu root, roselle and gardenia in water, heat to 115-125℃ and steam for 20-40 minutes. Cool and set aside; Step 2: Crush bergamot, polygonatum, tangerine peel and amomum villosum, add larix raphanii, soak in water for 120-240 minutes, heat and extract, filter, and set aside the filtrate; Step 3: Wash dandelion, purslane, hawthorn and mulberry, soak them in water for 120-240 minutes, heat and extract, filter and set aside the filtrate; Step 4, mix the liquids from steps 1, 2, and 3 and set aside; Step 5, soaking Cassia seed, Citrus aurantium, hemp seed and peach kernel in water for 120-240 minutes, heating and extracting, filtering and setting aside the filtrate; Step 6: Add the liquid obtained in steps 4 and 5 to the chamomile extract and mix well. Then pasteurize and can.

7. The method for preparing the quick sobering and liver-protecting drink according to claim 6, characterized in that: In the first step, the pressurized pressure is not less than 0.2 MPa, and the cooking is performed for 30 minutes.

8. The method for preparing the quick sobering up and liver protecting drink according to claim 6, characterized in that: In the step 6, the sterilization temperature does not exceed 90°C.

9. The quick sobering and liver protecting drink according to any one of claims 1 to 3, characterized in that: The drink is medicine or food.

10. Use of the quick sobering up and liver protecting drink according to any one of claims 1 to 3 in the preparation of quick sobering up and liver protecting medicines.

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