Wound ointment
By developing a trauma ointment containing catecha, Viagra, Atractylodes macrocephala, Astragalus, Dragon Blood Fever and White Vaseline, the shortcomings of existing skin trauma treatment drugs in terms of treatment effects, pain relief and scar prevention have been solved, and the effect of quickly reducing pain, promoting neocutaneous production and speeding up recovery has been achieved.
Patent Information
- Application Number
- CN202411662846.1
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2024-11-20
- Publication Date
- 2025-03-04
AI Technical Summary
The existing drugs for treating skin trauma have shortcomings in the treatment effect, pain relief and scar prevention, and the treatment cycle is long and the efficacy is slow.
Provide a wound ointment containing catecha, Viagra, Atractylodes, Astragalus, Dragon Blood Fever and White Vaseline, which is made into a paste by grinding and heating for direct application or bandaging.
This wound ointment can quickly penetrate deep into the skin, relieve pain, promote the generation of new skin, speed up the patient's recovery progress, improve the quality of life, and be pain-free, anti-infection during the treatment process, remove volatilization, and heal quickly.
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Abstract
Description
Technical Field
[0001] The invention belongs to the technical field of traditional Chinese medicines, in particular to a wound ointment for treating skin wounds such as knife wounds, scalds or bedsores. Background Art
[0002] Skin trauma such as knife wounds and burns are common accidental injuries in people's daily lives. For long-term bedridden patients, due to long-term pressure on local tissues, blood circulation is blocked, and continuous ischemia, hypoxia, and malnutrition occur, resulting in tissue ulceration and necrosis, that is, bedsores (also known as pressure ulcers). These skin traumas will destroy the normal skin's natural antibacterial barrier defense ability, which will not only cause severe pain to the patient, but also easily lead to deeper and deeper wounds, complicated by infection, and thus cause internal injuries to the patient. There are many existing drugs for the treatment of skin trauma, including traditional Chinese medicine and Western medicine. According to many years of clinical observation, the existing traditional Chinese medicine has slow pain relief, poor treatment effect, and is easy to leave scars; while Western medicine is mainly anti-inflammatory and bactericidal, mainly relying on the patient's own repair ability to heal the wound, with a long treatment cycle and slow efficacy. Summary of the invention
[0003] The purpose of the present invention is to provide a wound ointment for the treatment of large-area skin wounds such as knife wounds, scalds or bedsores, which can increase blood circulation to remove inflammatory mediators, relieve pain, promote new skin formation, and accelerate the patient's recovery progress.
[0004] In order to solve the above technical problems, the present invention provides a wound ointment, comprising the following components in parts by weight: 2-4 parts of catechu, 30-60 parts of clematis, 10-20 parts of atractylodes, 45-50 parts of astragalus, 4-6 parts of dragon's blood, and 100 parts of white vaseline;
[0005] The preparation method thereof is:
[0006] (1) Grind catechu, clematis root, atractylodes macrocephala, astragalus root and dragon's blood into Chinese medicinal powder according to proportion and mix them evenly;
[0007] (2) Add the evenly mixed Chinese medicine powder to white vaseline, stir evenly and heat to 50°C and boil for 20-30 minutes to make a paste. After cooling, put it into a sterilized medicine box and seal it for later use.
[0008] Furthermore, the wound plaster of the present invention preferably comprises the following components in parts by weight: 3 parts of catechu, 50 parts of clematis, 15 parts of atractylodes, 50 parts of astragalus, 5 parts of dragon's blood, and 100 parts of white vaseline.
[0009] Catechu can not only promote blood circulation and stop bleeding, reduce swelling and relieve pain, but also kill bacteria and have good antibacterial effects on Staphylococcus aureus, Gram-positive cocci and Gram-negative bacilli; Clematis has the effects of dredging meridians, antibacterial and anti-inflammatory, and analgesic, and also has a diuretic effect, which helps to regulate the body's metabolism and relieve swelling to a certain extent, and relieves the patient's pain and discomfort; Atractylodes macrocephala polysaccharide has the effect of enhancing the body's immune function, can improve cellular immune function, and promote skin regeneration; Astragalus can play a role in healing wounds and promoting tissue regeneration after sores and ulcers have ruptured and cannot heal; Dragon's Blood has the effects of promoting blood circulation and dispersing blood stasis, relieving pain and stopping bleeding, healing wounds and promoting tissue regeneration, and can activate coagulation factors, so that the blood in a low coagulation state can coagulate at the rupture to stop bleeding. Dragon's Blood contains plant defensins, which have antifungal and antiseptic effects, can remove dead tissue and promote tissue regeneration, can effectively control wound infection, and promote wound healing; White Vaseline has an excellent moisturizing effect, can form a special protective film on the skin, and effectively block the influence of external factors on the skin.
[0010] The wound ointment of the invention is easy to disperse, is conducive to absorption by the compress, is used for treating large-area skin wounds, and has a good therapeutic effect on knife wounds, scalds and bedsores. The preparation method is simple, the dosage is easy to control, the drug quality is stable, and the patient can apply it by himself, which is relatively convenient.
[0011] The wound ointment of the present invention has the main effects of hemostasis, tissue regeneration, blood stasis and pain relief, blood circulation and swelling reduction, tissue regeneration and skin healing. It is used for the late treatment of large-area wound infection such as knife wounds, scalds or bedsores, etc., and can increase blood circulation to remove inflammatory mediators from the affected area, reduce swelling and pain of patients, promote new skin formation, accelerate the recovery progress of patients, and improve the quality of life of patients.
[0012] The wound ointment of the present invention is based on the theory of traditional Chinese medicine, and is treated according to the principle of syndrome differentiation, and is refined in close combination with modern medicine and advanced technology. As is well known, there are many similar formulas for treating diseases with Chinese medicine, but sometimes the effect of the medicine will be significantly different due to the adjustment of a medicine or a partial dose, and sometimes the effect of the medicine will be significantly different. Therefore, drug compatibility is the key to the effect of the medicine. The wound ointment of the present invention has been reasonably matched, screened, and formulated by the selected Chinese medicine for many years, and can quickly penetrate into the deep layer of the skin, clear away heat and detoxify, prevent corruption and promote muscle growth, promote blood circulation and remove blood stasis, activate tissue regeneration and memory ability, and prevent scar formation. After more than 10,000 cases of various degrees of knife wounds, scalds, and bedsores, the clinical use is non-toxic, harmless, and has no side effects, with an effective rate of 96% and a cure rate of 98%. In the whole treatment process, there is no pain, anti-infection, dehumidification and muscle growth, and the wound heals rapidly. BRIEF DESCRIPTION OF THE DRAWINGS
[0013] Figure 1 It is a comparison diagram of the wound ointment of the present invention in treating knife wounds.
[0014] Figure 2It is a comparison diagram of the wound ointment of the present invention in treating burns. DETAILED DESCRIPTION
[0015] The present invention will be further described below in conjunction with specific implementation modes.
[0016] Example 1
[0017] This embodiment provides a wound ointment, comprising the following components in parts by weight: 2 parts of catechu, 60 parts of clematis, 10 parts of atractylodes, 50 parts of astragalus, 4 parts of dragon's blood, and 100 parts of white vaseline;
[0018] The preparation method thereof is:
[0019] (1) Grind catechu, clematis root, atractylodes macrocephala, astragalus root and dragon's blood into Chinese medicinal powder according to proportion and mix them evenly;
[0020] (2) Add the evenly mixed Chinese medicine powder to white vaseline, stir evenly and heat to 50°C and boil for 20-30 minutes to make a paste. After cooling, put it into a sterilized medicine box and seal it for later use.
[0021] The method of use is: apply the wound ointment directly on the wound, or apply it on the surface of sterilized gauze and then bandage it with medicated gauze. Change the dressing every 1 to 2 days until the wound heals and new skin grows.
[0022] Example 2
[0023] The present embodiment provides a wound ointment, comprising the following components in parts by weight: 3 parts of catechu, 50 parts of clematis, 15 parts of atractylodes, 50 parts of astragalus, 5 parts of dragon's blood, and 100 parts of white vaseline.
[0024] The preparation method and use method are the same as those in Example 1.
[0025] Example 3
[0026] The present embodiment provides a wound ointment, comprising the following components in parts by weight: 4 parts of catechu, 30 parts of clematis, 20 parts of atractylodes, 50 parts of astragalus, 6 parts of dragon's blood, and 100 parts of white vaseline.
[0027] The preparation method and use method are the same as those in Example 1.
[0028] Comparative Example 1
[0029] 3 parts of catechu, 50 parts of clematis, 15 parts of atractylodes, 50 parts of astragalus, and 100 parts of white vaseline.
[0030] Comparative Example 2
[0031] 50 parts of Clematidis Radix, 15 parts of Atractylodes Macrocephala, 50 parts of Radix Astragali, 5 parts of Dragon's Blood Jelly, and 100 parts of white vaseline.
[0032] Comparative Example 3
[0033] 10 parts of catechu, 50 parts of clematis, 15 parts of atractylodes, 50 parts of astragalus, 1 part of dragon's blood, and 100 parts of white vaseline.
[0034] Knife wound treatment effect:
[0035] A total of 28 healthy adult mice, half male and half female, were depilated on the back to form a 2cm×3cm depilated surface, and scratched with a knife to form a wound of about 2cm in length and about 0.2cm in depth. The mice were randomly divided into a blank group, a control group and an experimental group, with 4 mice in each group, 2 of which were male and 2 were female. The blank group was only debrided and disinfected, the control group was bandaged with gauze coated with the ointment of Comparative Examples 1-3 after debriding and disinfection, and the experimental group was bandaged with gauze coated with the wound ointment of Examples 1-3 after cleaning and disinfection. The dressing was changed once a day, and the wound was cleaned and disinfected before each dressing change (the blank group was only cleaned and disinfected). The scab time and scab rate were compared, and the results are shown in Table 1.
[0036] As can be seen from Table 1, the wound ointment of the present invention can generally heal by scab within 5 days, the scab rate of the blank group in 5 days was only 56%, and the scab healed after 11 days, and the wound was uneven and had scars; the control group healed by scab in 8 days, and after the experimental group continued to administer the drug for 3 days, the scab fell off, and the wound was flat without scars, indicating that the wound ointment of the present invention is fast in effect in treating knife wounds, and has a good effect without leaving scars.
[0037] Typical cases:
[0038] Patient, male, 43 years old, had glass piercing his toe. The broken glass was removed with tweezers and disinfected with hydrogen peroxide, and then bandaged with gauze coated with Example 3 wound ointment. The coated gauze was disinfected and replaced twice a day for the first 2 days, once a day for the next 3 days, and once every two days for the next 5 days. On the 5th day, the pain basically disappeared, with only slight discomfort. After 10 days, the pain completely disappeared, and the wound began to heal. Figure 1 shown.
[0039] Table 1 Wound recovery in blank group, control group and experimental group
[0040]
[0041] Typical cases of burn treatment:
[0042] The patient, a 68-year-old female, had second-degree burns on both legs. The burns were large in area. She started taking medication on the second day. Before taking the medication, there were dense blisters on the wound surface. Figure 2As shown, the tingling sensation was obvious. The blisters were punctured with a sterile needle and bandaged with gauze coated with the wound ointment of Example 3. The tingling sensation was significantly relieved on the same day. The dressing was changed every two days thereafter, and the wound surface was not exposed to water during the period. The pain basically disappeared on the 5th day of applying the medicine. On the 15th day of applying the medicine (the 16th day of scalding), the scalded skin on the wound surface began to scab and fall off, and new skin was generated, as shown in FIG. Figure 2 shown.
[0043] The above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit them. A person skilled in the art should understand that the technical solutions described in the above embodiments may still be modified, or some of the technical features may be replaced by equivalents. However, these modifications or replacements will not cause the essence of the corresponding technical solutions to deviate from the protection scope of the present invention.
Claims
1. A wound ointment, characterized in that: Contains the following components in parts by weight: 2-4 servings of catechu; 30-60 portions of Clematis chinensis; 10-20 portions of Atractylodes macrocephala; 45-50 parts of Astragalus; 4-6 parts of dragon's blood; 100 parts of white vaseline; The preparation method is: (1) Grind catechu, clematis root, atractylodes macrocephala, astragalus root and dragon's blood into powder according to proportion and mix them evenly; (2) Add the evenly mixed Chinese medicine powder to white vaseline, stir evenly and heat to 50°C and boil for 20-30 minutes to make a paste. After cooling, put it into a sterilized medicine box and seal it for later use.
2. The wound ointment according to claim 1, wherein The composition comprises the following components in parts by weight: catechu 3 parts; Clematis 50 parts; Atractylodes macrocephala 15 parts; Astragalus 50 parts; 5 parts of dragon's blood; 100 parts of white vaseline.
3. Application of the trauma ointment according to claim 1 or 2 in treating knife wounds.
4. Application of the trauma ointment according to claim 1 or 2 in treating scalds.
5. Use of the trauma ointment according to claim 1 or 2 in treating bedsores.