Culture device for preparing immune cells
By using the rubber ring and the groove wheel in the culture device prepared by immune cells, the excessive splashing and damage of the material caused by shaking inertia is solved, and the safety and stability of the culture material during shaking is achieved.
Patent Information
- Application Number
- CN202411645305.8
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2024-11-18
- Publication Date
- 2025-03-04
- Estimated Expiration
- Not applicable · inactive patent
AI Technical Summary
During the shaking process of existing culture devices for immune cells, the material vibration amplitude is too large due to the shaking inertia, causing excessive splashing of the material or damage to the culture material.
A culture device including a mating of a rubber ring and a groove wheel is designed. Through the close fit between the rubber pad and the groove wheel surface, friction is increased, and the rotation of the groove wheel is restricted, and the material is prevented from excessive splashing or damage.
It effectively prevents excessive splashing and damage of the material due to shaking inertia, and ensures the safety and stability of the cultured material during shaking.
Smart Images
Figure CN119552741A_ABST
Abstract
Description
Technical Field
[0001] The invention relates to the technical field of cell culture, in particular to a culture device for preparing immune cells. Background Art
[0002] At present, the culture devices for preparing immune cells mainly include carbon dioxide incubators, shaker culture devices, bioreactors and rotary culture devices, among which the shaker culture device is mainly composed of a shaker platform, a drive motor, a control system, etc. The shaker platform can perform horizontal or inclined reciprocating motion, and culture containers such as culture bottles and culture dishes are placed on it. Through continuous shaking, the cells can be evenly exposed to nutrients and oxygen in the culture solution, which promotes cell growth and metabolism, can effectively increase the contact area and frequency between cells and the culture solution, increase the nutrient supply and oxygen exchange of cells, and is conducive to the rapid growth and proliferation of cells; When the shaking culture equipment is working, during the shaking process, due to the shaking inertia, the material vibration amplitude is too large, causing excessive splashing of the material or causing the culture material to be damaged during the vibration generated by the shaking. Summary of the invention
[0003] To achieve the above objectives, the present invention is implemented through the following technical solutions: A culture device for preparing immune cells, comprising: A cabinet, a heater is fixedly installed on the top of the cabinet, a water outlet pipe and a water inlet pipe are installed at the water inlet and the water outlet of the heater respectively, and cylinders are fixedly installed on both sides of the cabinet; A shaking mechanism, which is used to shake the culture bottle, and the shaking mechanism is installed inside the cabinet, and the output end of the cylinder is connected to the shaking mechanism; A water bed mechanism, which is used to contain warm water and is installed inside the shaking mechanism; A fixing mechanism, which is used to fix the culture bottle, and the fixing mechanism is installed inside the shaking mechanism, and the fixing mechanism is located above the water bed mechanism; The shaking mechanism comprises side plates, which are symmetrically mounted on the inner wall of the cabinet along the axis center position of the cabinet, an inner slide plate is slidably mounted between the side plates, groove blocks are fixedly mounted on the opposite surfaces of the inner slide plate, and connecting blocks are fixedly mounted on the non-opposite surfaces of the inner slide plate, the bottom of the connecting block is connected to the output end of the cylinder, the groove blocks are symmetrically mounted along the axis center position of the inner slide plate, and a wheel groove is provided on the outer side of the groove block, a groove wheel is rotatably mounted at the wheel groove of the groove block, a rubber pad is fixedly mounted on the inner wall of the groove block, and the groove wheel moves up and down on the connecting plate through the cooperation of the rubber ring and the groove wheel, and during the rotation, the groove wheel rotates in the wheel groove of the groove block, and the friction force of the groove wheel during the rotation is increased by the close fit between the rubber pad and the surface of the groove wheel, and the rotation of the groove wheel and the connecting plate is limited in the process of no external force driving the groove wheel to rotate, so as to prevent the material from vibrating too much due to the shaking inertia during the shaking of the culture material, causing excessive splashing of the material or causing damage to the culture material during the vibration caused by the shaking, and the opposite surface of the rubber pad is in close contact with the outer side of the groove wheel.
[0004] Preferably, a connecting plate is fixedly installed on the opposite surface of the groove wheel, and an arc panel is fixedly installed on the outer side of the connecting plate, the outer side of the arc panel is an arc surface, and the arc panel is installed diagonally on the outer side of the connecting plate, and a ball block is fixedly installed on the outer side of the side plate, and the ball head of the ball block contacts the arc surface of the arc panel. In the process of the connecting plate moving up and down, the arc panel is restricted by the fixed ball block, so that the connecting plate is driven by the arc panel to rotate, thereby achieving shaking of the culture material. At the same time, in the process of rotation, the arc surface of the arc surface block is used to control the rotation amplitude to avoid excessive rotation angle, which causes splashing of the shaking culture material. The ball block is provided with a ball head, and the ball head of the ball block contacts the arc surface of the arc panel. The opposite surface of the connecting plate is connected to the fixing mechanism, and a slot rod is fixedly installed on the outer side of the side plate, and the opposite surface of the slot rod is symmetrically provided with grooves, and the slot rod is clamped with the water bed mechanism through the groove.
[0005] Preferably, the fixing mechanism includes a circular groove plate, both ends of the circular groove plate are fixedly connected to the opposite surfaces of the connecting plate, and the top of the circular groove plate is evenly provided with circular grooves along the axial direction, and annular pads are fixedly installed at the circular grooves of the circular groove plate, and the circular grooves of the circular groove plate are fixed by the annular pads. During the shaking of the conical flask, when the conical flask contacts the annular pads, the conical flask is protected to prevent the conical flask from swinging and breaking due to incomplete fixation during the shaking process, and a fixing block is fixedly installed on the top of the circular groove plate, and the fixing block is symmetrically installed along the center position of the circular groove axis of the circular groove plate, and a threaded ring is rotatably installed on the opposite surface of the fixing block, and a threaded rod is slidably installed on the inner wall of the fixing block.
[0006] Preferably, the outer side of the threaded rod is threadedly connected to the inner wall of the threaded ring, and an arc clamp block is fixedly installed at one end of the threaded rod, the side of the arc clamp block away from the threaded rod is an arc surface, and the outer side of the threaded ring is fixedly installed with a side block, and the side blocks are symmetrically installed along the center position of the axis of the threaded ring, and an elastic ring is provided at the bottom of the threaded ring. Through the elastic deformation of the elastic ring, during the shaking of the conical flask, through the contact between the side block and the elastic ring, after the threaded ring shows a tendency of relative rotation, the tendency is transmitted to the elastic ring through the side block, so that the elastic ring synchronously deforms and expands, thereby increasing the contact pressure with the threaded ring, limiting the rotation of the threaded ring, and preventing the threaded rod from moving during the shaking process, which causes the fixing effect of the conical flask to be reduced, and the two sides of the elastic ring are in contact with the bottom of the side block.
[0007] Preferably, the water bed mechanism includes a water tank box, the bottom of the water tank box is clamped with the groove of the tank rod, and the inner wall of the water tank box is fixedly installed with a fixed pipe and a water guide cover, the water guide cover and the fixed pipe are installed diagonally along the water tank box, the bottom of the water guide cover is fixedly installed with a connecting pipe, the end of the connecting pipe away from the water guide cover is connected to the water outlet pipe, and the bottom end of the fixed pipe is connected to the water inlet pipe, the top of the inner wall of the water guide cover is clamped with a filter hole cover, the center position of the bottom of the filter hole cover protrudes upward, and the flowing water is filtered through the inner filter holes of the filter hole cover, and the upward protrusion of the center position causes the filtered foreign matter to accumulate around the inner cavity of the filter hole cover to avoid the filter hole cover being completely blocked, resulting in the water in the water tank box being unable to circulate, heat and flow, resulting in the water temperature being unable to be constant, and the inner wall of the water guide cover is fixedly installed with a support ring, and the inner wall of the support ring is rotatably installed with a rotating wheel.
[0008] The present invention provides a culture device for preparing immune cells, which has the following beneficial effects: 1. The culture device for preparing immune cells moves up and down on the connecting plate through the cooperation between the rubber ring and the groove wheel. During the rotation, the groove wheel rotates in the wheel groove of the groove block. The rubber pad is closely fitted with the surface of the groove wheel to increase the friction force when the groove wheel rotates. In the process where there is no external force to drive the groove wheel to rotate, the rotation of the groove wheel and the connecting plate is limited to prevent the material from vibrating too much due to the shaking inertia during the shaking of the culture material, causing excessive splashing of the material or causing the culture material to be damaged during the vibration generated by the shaking.
[0009] 2. The culture device for preparing immune cells has a ball head of a ball block in contact with the arc surface of an arc panel. During the up and down movement of the connecting plate, the arc panel is restricted by the fixed ball block, so that the connecting plate is driven by the arc panel to rotate, thereby shaking the culture material. At the same time, during the rotation, the arc surface of the arc surface block controls the rotation amplitude to avoid excessive rotation angles, which would cause splashing of the shaking culture material.
[0010] 3. The culture device for preparing immune cells is fixed at the circular groove of the circular groove plate by the annular pad. When the conical flask contacts the annular pad during shaking, the conical flask is protected to prevent the conical flask from swinging and breaking due to incomplete fixation during shaking.
[0011] 4. The culture device for preparing immune cells, through the elastic deformation of the elastic ring, during the shaking of the conical flask, through the contact between the side block and the elastic ring, after the threaded ring shows a tendency to relatively rotate, the tendency is transmitted to the elastic ring through the side block, so that the elastic ring synchronously deforms and expands, increases the contact pressure with the threaded ring, limits the rotation of the threaded ring, prevents the threaded rod from moving during the shaking process, and causes a reduction in the fixing effect of the conical flask.
[0012] 5. The culture device for preparing immune cells filters the flowing water through the inner filter holes of the filter cover. At the same time, the upward protrusion at the center position allows the filtered foreign matter to accumulate around the inner cavity of the filter cover, thereby preventing the filter cover from being completely blocked, resulting in the inability to circulate, heat and flow the water in the water tank, resulting in the water temperature not being constant. BRIEF DESCRIPTION OF THE DRAWINGS
[0013] Figure 1 A schematic diagram of the external structure of a culture device for preparing immune cells according to the present invention; Figure 2 This is a structural anatomical diagram of a culture device for preparing immune cells according to the present invention; Figure 3 It is a schematic diagram of the structure of the shaking mechanism of the present invention; Figure 4 It is a side view of the shaking mechanism structure of the present invention; Figure 5 It is a partial structural schematic diagram of the shaking mechanism of the present invention; Figure 6 It is a schematic diagram of the fixing mechanism structure of the present invention; Figure 7 It is a partial structural schematic diagram of the fixing mechanism of the present invention; Figure 8 It is a schematic diagram of the water bed structure of the present invention; Fig. 9 It is a partial structural schematic diagram of the water bed mechanism of the present invention; Fig.10 It is a partial structural dissection diagram of the water bed mechanism of the present invention.
[0014] In the figure: 1, cabinet; 2, shaking mechanism; 3, water bed mechanism; 4, fixing mechanism; 5, cylinder; 6, water outlet pipe; 7, heater; 8, water inlet pipe; 201, side plate; 202, inner slide plate; 203, connecting block; 204, connecting plate; 205, groove rod; 206, groove wheel; 207, rubber pad; 208, groove block; 209, arc panel; 210, ball block; 31, water tank box; 32, connecting pipe; 33, fixing pipe; 34, water guide cover; 35, filter hole cover; 36, support ring; 37, rotating wheel; 41, circular groove plate; 42, annular pad; 43, fixing block; 44, threaded rod; 45, threaded ring; 46, elastic ring; 47, arc clamp block; 48, side block. DETAILED DESCRIPTION
[0015] The present invention is further described in detail below in conjunction with the accompanying drawings and specific embodiments. The embodiments of the present invention are provided for the purpose of illustration and description, and are not intended to be exhaustive or to limit the present invention to the disclosed forms. Many modifications and variations will be apparent to those of ordinary skill in the art. The embodiments are selected and described in order to better illustrate the principles and practical applications of the present invention, and to enable those of ordinary skill in the art to understand the present invention and thereby design various embodiments with various modifications suitable for specific uses.
[0016] The first embodiment, as Figures 1 to 5 As shown, the present invention provides a technical solution: a culture device for preparing immune cells, comprising: A cabinet 1, a heater 7 is fixedly installed on the top of the cabinet 1, a water outlet pipe 6 and a water inlet pipe 8 are installed at the water inlet and the water outlet of the heater 7 respectively, and a cylinder 5 is fixedly installed on both sides of the cabinet 1; A shaking mechanism 2, which is used to shake the culture bottle, and the shaking mechanism 2 is installed inside the cabinet 1, and the output end of the cylinder 5 is connected to the shaking mechanism 2; A water bed mechanism 3, which is used to contain warm water and is installed inside the shaking mechanism 2; A fixing mechanism 4, which is used to fix the culture bottle, and the fixing mechanism 4 is installed inside the shaking mechanism 2, and the fixing mechanism 4 is located above the water bed mechanism 3; The rocking mechanism 2 includes a side plate 201, which is symmetrically mounted on the inner wall of the cabinet 1 along the center position of the axis of the cabinet 1, and an inner slide plate 202 is slidably mounted between the side plates 201. The opposite surfaces of the inner slide plate 202 are fixedly mounted with groove blocks 208, and the non-opposite surfaces of the inner slide plate 202 are fixedly mounted with connecting blocks 203. The bottom of the connecting block 203 is connected to the output end of the cylinder 5. The groove block 208 is symmetrically mounted along the center position of the axis of the inner slide plate 202, and a wheel groove is provided on the outer side of the groove block 208. A groove wheel 206 is rotatably mounted at the wheel groove of the groove block 208. During the movement, the ball head of the ball block 210 is contacted through the arc panel 209, and the ball block 210 is moved by the side After the plate 201 is fixed, during the up and down movement of the groove block 208, the arc plate 209 drives the connecting plate 204 to move up and down and rotate left and right. At the same time, the fixing mechanism 4 drives the conical flask to shake, so that the culture liquid in the conical flask shakes. At the same time, during the rotation of the connecting plate 204, the groove wheel 206 rotates with the connecting plate 204. When the groove wheel 206 rotates in the wheel groove of the groove block 208, the rubber pad 207 fits tightly with the surface of the groove wheel 206, so that the rubber pad 207 and the surface of the groove wheel 206 generate greater friction. The inner wall of the groove block 208 is fixedly installed with the rubber pad 207, and the opposite surface of the rubber pad 207 fits tightly with the outer side of the groove wheel 206.
[0017] A connecting plate 204 is fixedly installed on the opposite surface of the groove wheel 206, and an arc panel 209 is fixedly installed on the outer side of the connecting plate 204. The outer side of the arc panel 209 is an arc surface, and the arc panel 209 is installed diagonally on the outer side of the connecting plate 204. A ball block 210 is fixedly installed on the outer side of the side plate 201. The ball block 210 is provided with a ball head, and the ball head of the ball block 210 contacts the arc surface of the arc panel 209. In the process of driving the shaking mechanism 2 to move by the cylinder 5, it is connected to the connecting block 203 through the cylinder 5, so that the output end drives the inner slide 202 to move up and down through the connecting block 203, so that the inner slide 202 drives the groove block 208 to move together, and the opposite surface of the connecting plate 204 is connected to the fixing mechanism 4. A groove rod 205 is fixedly installed on the outer side of the side plate 201, and the opposite surface of the groove rod 205 is symmetrically provided with grooves, and the groove rod 205 is clamped with the water bed mechanism 3 through the groove.
[0018] The second embodiment is based on the first embodiment. Figure 6 to Figure 7As shown, the fixing mechanism 4 includes a circular groove plate 41, both ends of which are fixedly connected to the opposite surfaces of the connecting plate 204, and the top of the circular groove plate 41 is uniformly provided with circular grooves along the axial direction, and annular pads 42 are fixedly installed at the circular grooves of the circular groove plate 41, and a fixing block 43 is fixedly installed on the top of the circular groove plate 41, which is fixedly connected to the connecting plates 204 on both sides through the circular groove plate 41, so that the connecting plates 204 move up and down and rotate, and the fixing block 43 is driven to move together through the circular groove plate 41. When fixing the conical flask loaded with culture materials, the threaded rods 44 on both sides are moved close to the center position by rotating the threaded ring 45, and the conical flask is clamped and fixed by the arc clamping block 47 contacting the bottleneck of the conical flask. The fixing block 43 is symmetrically installed along the center position of the circular groove axis of the circular groove plate 41, and the opposite surface of the fixing block 43 is rotatably installed with the threaded ring 45, and the inner wall of the fixing block 43 is slidably installed with the threaded rod 44.
[0019] The outer side of the threaded rod 44 is threadedly connected to the inner wall of the threaded ring 45, and an arc clamp block 47 is fixedly installed at one end of the threaded rod 44. The side of the arc clamp block 47 away from the threaded rod 44 is an arc surface. The outer side of the threaded ring 45 is fixedly installed with a side block 48. The side block 48 is symmetrically installed along the center position of the axis of the threaded ring 45. In the process of shaking the conical flask, the elastic ring 46 restricts the side block 48, so that in the process of shaking the conical flask, the threaded ring 45 is restricted by the side block 48. When the threaded ring 45 has a tendency to rotate, the rotation tendency is transmitted to the elastic ring 46 through the side block 48, so that the elastic ring 46 has a tendency to deform and expand, increasing the friction between the threaded ring 45 and the threaded ring 45. The rotation of the threaded ring 45 is restricted, and then the position of the threaded rod 44 is restricted. The bottom of the threaded ring 45 is provided with an elastic ring 46, and the two sides of the elastic ring 46 are in contact with the bottom of the side block 48.
[0020] The third embodiment is based on the first and second embodiments. Figures 8 to 10As shown, the water bed mechanism 3 includes a water tank box 31, the bottom of the water tank box 31 is clamped with the groove of the groove rod 205, and the inner wall of the water tank box 31 is fixedly installed with a fixed pipe 33 and a water guide cover 34, the water guide cover 34 and the fixed pipe 33 are installed along the diagonal of the water tank box 31, and the water tank box 31 carries warm water, so that the water in the water tank box 31 flows out through the water outlet pipe 6, is introduced into the heater 7 for heating, and then is introduced into the water tank box 31 through the water inlet pipe 8, so that the water in the water tank box 31 is at a constant temperature range, and the culture material in the conical flask is heated by the contact of the warm water with the conical flask, so that the culture material is at a suitable temperature, thereby accelerating the culture speed, and the bottom of the water guide cover 34 is fixedly installed with a connecting pipe 32, and the connecting pipe 32 is away from the guide pipe 34. One end of the water cover 34 is connected to the water outlet pipe 6, and the bottom end of the fixed pipe 33 is connected to the water inlet pipe 8. The top of the inner wall of the water guide cover 34 is clamped with a filter hole cover 35, and the center position of the bottom of the filter hole cover 35 protrudes upward. When water flows, it is connected to the water inlet pipe 8 through the fixed pipe 33, so that the heated water is introduced into the water tank box 31. The water in the water tank box 31 is discharged through the water guide cover 34 and connected to the water outlet pipe 6 through the connecting pipe 32 at the bottom of the water guide cover 34, so that the water in the water tank box 31 circulates, heats and flows. At the same time, when the water in the water tank box 31 is discharged, the water flowing through is filtered by the filter hole cover 35. A support ring 36 is fixedly installed on the inner wall of the water guide cover 34, and a rotating wheel 37 is rotatably installed on the inner wall of the support ring 36.
[0021] When in use, workers put the prepared culture materials into the conical flask, and then fix the conical flask through the fixing mechanism 4. After the conical flask is fixed, the water inlet of the heater 7 is connected to the water outlet pipe 6, and the water inlet pipe 8 is connected to the water outlet of the heater 7. The heater 7 drives water to circulate and heat the water flowing through, so that the temperature of the water in the water bed mechanism 3 is within a constant range. The temperature of the culture solution is controlled by the contact between the water and the conical flask. At the same time, the cylinder 5 drives the shaking mechanism 2, so that the shaking mechanism 2 drives the fixing mechanism 4 to shake the conical flask.
[0022] In the process of driving the shaking mechanism 2 to move by the cylinder 5, the cylinder 5 is connected to the connecting block 203, so that the output end drives the inner slide plate 202 to move up and down through the connecting block 203, and the inner slide plate 202 drives the groove block 208 to move together. At the same time, during the movement, the arc panel 209 contacts the ball head of the ball block 210. At the same time, after the ball block 210 is fixed by the side plate 201, during the up and down movement of the groove block 208, the arc panel 209 drives the connecting plate 204 to move up and down and rotate left and right. At the same time, the conical flask is shaken through the fixing mechanism 4, so that the culture solution in the conical flask is shaken. At the same time, during the rotation of the connecting plate 204, the groove wheel 206 rotates with the connecting plate 204. When the groove wheel 206 rotates in the wheel groove of the groove block 208, the rubber pad 207 is closely fitted with the surface of the groove wheel 206, so that the rubber pad 207 and the surface of the groove wheel 206 generate greater friction.
[0023] When the fixing mechanism 4 is driven by the shaking mechanism 2, the circular groove plate 41 is fixedly connected to the connecting plates 204 on both sides, so that the connecting plates 204 move up and down and rotate, and the circular groove plate 41 drives the fixing block 43 to move together. When fixing the conical flask loaded with culture material, the threaded rods 44 on both sides are moved closer to the center position by rotating the threaded ring 45, and the conical flask is clamped and fixed by the arc clamp block 47 contacting the bottleneck of the conical flask. At the same time, in the process of shaking the conical flask, the elastic ring 46 restricts the side block 48, so that in the process of shaking the conical flask, the threaded ring 45 is restricted by the side block 48. When the threaded ring 45 has a tendency to rotate, the rotation tendency is transmitted to the elastic ring 46 through the side block 48, so that the elastic ring 46 has a tendency to deform and expand, thereby increasing the friction between the threaded ring 45 and the threaded ring 45, thereby restricting the rotation of the threaded ring 45, and then restricting the position of the threaded rod 44.
[0024] When water is carried by the water bed mechanism 3, warm water is carried by the water tank box 31, so that the water in the water tank box 31 flows out through the water outlet pipe 6, is introduced into the heater 7 for heating, and then is introduced into the water tank box 31 through the water inlet pipe 8, so that the water in the water tank box 31 is at a constant temperature range, and the culture material in the conical flask is heated by the contact of the warm water with the conical flask, so that the culture material is at a suitable temperature and the culture speed is accelerated. At the same time, when the water flows, it is connected to the water inlet pipe 8 through the fixed pipe 33, so that the heated water is introduced into the water tank box 31, and the water in the water tank box 31 is discharged through the water guide cover 34, and is connected to the water outlet pipe 6 through the connecting pipe 32 at the bottom of the water guide cover 34, so that the water in the water tank box 31 is circulated, heated and flows, and at the same time, when the water in the water tank box 31 is discharged, the water flowing through is filtered by the filter hole cover 35.
[0025] Obviously, the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field and related fields without creative work should fall within the scope of protection of the present invention. The structures, devices and operating methods not specifically described and explained in the present invention are implemented according to the conventional means in the field unless otherwise specified and limited.
Claims
1. A culture device for preparing immune cells, characterized in that: include: A cabinet (1), a heater (7) being fixedly mounted on the top of the cabinet (1), a water outlet pipe (6) and a water inlet pipe (8) being mounted on the water inlet and the water outlet of the heater (7), respectively, and cylinders (5) being fixedly mounted on both sides of the cabinet (1); A shaking mechanism (2), the shaking mechanism (2) being used to shake the culture bottle, and the shaking mechanism (2) being installed inside the cabinet (1), and the output end of the cylinder (5) being connected to the shaking mechanism (2); A water bed mechanism (3), the water bed mechanism (3) being used to contain warm water, and the water bed mechanism (3) being installed inside the shaking mechanism (2); A fixing mechanism (4), the fixing mechanism (4) being used to fix the culture bottle, and the fixing mechanism (4) being installed inside the shaking mechanism (2), and the fixing mechanism (4) being located above the water bed mechanism (3); The rocking mechanism (2) comprises a side plate (201), the side plate (201) being symmetrically mounted on the inner wall of the cabinet (1) along the central position of the axis of the cabinet (1), an inner slide plate (202) being slidably mounted between the side plates (201), groove blocks (208) being fixedly mounted on the opposite surfaces of the inner slide plates (202), connecting blocks (203) being fixedly mounted on the non-opposite surfaces of the inner slide plates (202), the bottom of the connecting block (203) being connected to the output end of the cylinder (5), the groove blocks (208) being symmetrically mounted along the central position of the axis of the inner slide plates (202), a wheel groove being formed on the outer side of the groove blocks (208), a groove wheel (206) being rotatably mounted at the wheel groove of the groove blocks (208), a rubber pad (207) being fixedly mounted on the inner wall of the groove blocks (208), the opposite surface of the rubber pad (207) being tightly fitted to the outer side of the groove wheel (206).
2. A culture device for preparing immune cells according to claim 1, characterized in that: A connecting plate (204) is fixedly mounted on the opposite surface of the groove wheel (206); a curved panel (209) is fixedly mounted on the outer side of the connecting plate (204); the outer side of the curved panel (209) is a curved surface, and the curved panel (209) is diagonally mounted on the outer side of the connecting plate (204); a ball block (210) is fixedly mounted on the outer side of the side plate (201); the ball block (210) is provided with a ball head, and the ball head of the ball block (210) is in contact with the curved surface of the curved panel (209).
3. A culture device for preparing immune cells according to claim 2, characterized in that: The opposite surface of the connecting plate (204) is connected to the fixing mechanism (4), and a slot rod (205) is fixedly mounted on the outer side of the side plate (201). The opposite surface of the slot rod (205) is symmetrically provided with grooves, and the slot rod (205) is clamped with the water bed mechanism (3) via the grooves.
4. The culture device for preparing immune cells according to claim 3, characterized in that: The fixing mechanism (4) comprises a circular groove plate (41), the two ends of the circular groove plate (41) being fixedly connected to the opposite surfaces of the connecting plate (204), and the top of the circular groove plate (41) is evenly provided with circular grooves along the axial direction, and annular gaskets (42) are fixedly mounted at the circular grooves of the circular groove plate (41).
5. The culture device for preparing immune cells according to claim 4, characterized in that: A fixing block (43) is fixedly mounted on the top of the circular groove plate (41). The fixing block (43) is symmetrically mounted along the center position of the circular groove axis of the circular groove plate (41). A threaded ring (45) is rotatably mounted on the opposite surface of the fixing block (43). A threaded rod (44) is slidably mounted on the inner wall of the fixing block (43).
6. A culture device for preparing immune cells according to claim 5, characterized in that: The outer side of the threaded rod (44) is threadably connected to the inner wall of the threaded ring (45), and an arc clamping block (47) is fixedly mounted on one end of the threaded rod (44), and a side of the arc clamping block (47) away from the threaded rod (44) is an arc surface.
7. The culture device for preparing immune cells according to claim 6, characterized in that: A side block (48) is fixedly mounted on the outer side of the threaded ring (45), and the side block (48) is symmetrically mounted along the central position of the axis of the threaded ring (45). An elastic ring (46) is arranged at the bottom of the threaded ring (45), and two sides of the elastic ring (46) are in contact with the bottom of the side block (48).
8. The culture device for preparing immune cells according to claim 1, characterized in that: The water bed mechanism (3) comprises a water tank box (31), the bottom of the water tank box (31) being snap-fitted with a groove of a tank rod (205), and a fixed pipe (33) and a water guide cover (34) being fixedly mounted on the inner wall of the water tank box (31), the water guide cover (34) and the fixed pipe (33) being mounted along the diagonal edges of the water tank box (31).
9. A culture device for preparing immune cells according to claim 8, characterized in that: A connecting pipe (32) is fixedly mounted on the bottom of the water guide cover (34); one end of the connecting pipe (32) away from the water guide cover (34) is connected to the water outlet pipe (6), and the bottom end of the fixed pipe (33) is connected to the water inlet pipe (8).
10. The culture device for preparing immune cells according to claim 9, characterized in that: A filter hole cover (35) is clamped on the top of the inner wall of the water guide cover (34), the center position of the bottom of the filter hole cover (35) protrudes upwards, a support ring (36) is fixedly mounted on the inner wall of the water guide cover (34), and a rotating wheel (37) is rotatably mounted on the inner wall of the support ring (36).