Liquid medicine mixing maintaining system and method applied to high-pressure radiography injector
By dividing the contrast agent container into a mixing chamber and an injection chamber, maintaining the uniformity of the drug solution in the injection chamber, and performing regular remix operations in the mixing chamber, the problem of uneven mixing of the contrast agent caused by standing during the injection process is solved, and the contrast imaging effect is improved.
Patent Information
- Application Number
- CN202510141703.4
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-02-08
- Publication Date
- 2025-03-07
- Estimated Expiration
- Not applicable · inactive patent
AI Technical Summary
The existing automatic contrast mixing system of contrast agents is placed in the injection device for too long due to abnormal conditions such as vascular stenosis, tumor or blood viscosity during contrast agent injection, which affects the uniformity of the contrast agent.
The contrast agent container is divided into a mixing chamber and an injection chamber. By introducing a small dose of drug solution into the injection chamber, the uniformity of the drug solution is maintained, and the mixing operation is carried out regularly in the mixing chamber according to time and ambient temperature analysis to ensure the uniform mixing state of the drug solution.
Through this method, the mixing uniformity of the contrast agent during injection is ensured, the contrast imaging effect is improved, and the problem of uneven mixing caused by standing is avoided.
Smart Images
Figure CN119564979A_ABST
Abstract
Description
Technical Field
[0001] The invention relates to the field of high-pressure angiography, and in particular to a liquid medicine mixing and maintaining system and method applied to a high-pressure angiography injector. Background Art
[0002] Contrast agents are one of the most commonly used drugs in interventional radiology operations. They are mainly used to display blood vessels and body cavities and improve the accuracy of diagnosis. There are various types of contrast agents. Currently, most contrast agents used in interventional radiology are iodine-containing preparations. When using cardiac color Doppler ultrasound, contrast agents need to be injected into the human body for observation. In the process of angiography, in order to ensure accurate vascular images, the uniform dispersion of contrast agents is very important. Therefore, in the process of preparing contrast agents, contrast agents need to be mixed manually. In order to achieve automatic mixing of contrast agents, contrast agent mixing and injection mechanisms have been invented; At present, the existing automatic contrast agent mixing system has shortcomings. The existing contrast agent mixing is generally preliminarily mixed when the contrast agent is prepared, and is directly used on the contrast injection device after mixing. In actual application, if the patient's blood vessels are narrow or aneurysmal or the blood viscosity is poor during contrast injection, the injection of the contrast agent will be affected, thereby prolonging the contrast injection time during the artificial processing, and then causing the contrast agent to be placed in the injection device for too long, thereby affecting the uniformity of the contrast agent; In view of the above technical problems, this application proposes a solution. Summary of the invention
[0003] The present invention divides the contrast agent container into a mixing chamber and an injection chamber. A small dose of liquid medicine is introduced into the injection chamber so that the liquid medicine in the injection chamber maintains the requirements for injection contrast imaging. At the same time, the liquid medicine in the mixing chamber is analyzed according to the time experienced and the influence of the external environmental temperature, and re-mixing is performed when the set indicators are reached, thereby ensuring that the liquid medicine in the mixing chamber is always maintained in a uniformly mixed state, ensuring the mixing uniformity of the contrast agent itself when the contrast agent is injected, improving the contrast imaging effect, and solving the problem that the contrast agent is easily mixed into an uneven state due to long-term standing when the injection working time is too long. A liquid medicine mixing maintenance system and method for high-pressure contrast injection syringes are proposed.
[0004] The purpose of the present invention can be achieved through the following technical solutions: A drug liquid mixing and maintaining system applied to a high-pressure contrast injection syringe comprises an injection control unit, which collects the injection speed of the drug liquid and generates a control signal according to the collected injection speed of the drug liquid to control the injection speed of the drug liquid; a liquid medicine analysis unit, wherein the liquid medicine analysis unit analyzes the injection time of the liquid medicine according to the injection speed of the liquid medicine, obtains the maximum liquid medicine storage volume, and sends the maximum liquid medicine storage volume to the liquid medicine separation unit; A drug-liquid separation unit, which can collect drug-liquid parameters in the mixing chamber and the injection chamber, and transfer the drug-liquid in the mixing chamber to the injection chamber; A medicine quantity input unit, which obtains the quantity of medicine entering the mixing chamber, generates a mixing time signal according to the obtained result, and sends the mixing time signal to the mixing control unit; A mixing control unit, which can control the mixing operation of the liquid medicine according to the mixing time signal, calculate the real-time mixing time and the real-time maintenance interval according to the environmental interference characteristic value, and re-mix the liquid medicine according to the real-time mixing time and the real-time maintenance interval; A hybrid maintenance unit, wherein the hybrid maintenance unit obtains a hybrid timing signal through a hybrid control unit, collects environmental information, performs collection and analysis based on hybrid interference items in the environmental information, and generates a hybrid interference characteristic value based on the collection and analysis results.
[0005] As a preferred embodiment of the present invention, the injection control unit obtains the injection speed by manual input, and sends the injection speed to the liquid analysis unit; The drug liquid analysis unit obtains the drug liquid injection speed through the injection control unit, calculates the drug liquid injection speed and the drug liquid standing time, obtains the maximum drug liquid storage volume, and sends the maximum drug liquid storage volume to the drug liquid separation unit.
[0006] As a preferred embodiment of the present invention, the drug dosage input unit obtains the amount of drug entering the mixing chamber by manual input, and calculates the amount of solvent used for drug mixing by the set mixing ratio, and obtains the mixing time by multiplying the solvent amount by the set mixing diffusion speed, and sends the mixing time to the mixing control unit. The mixing control unit controls the stirring and mixing time in the mixing chamber according to the mixing time, and records the solvent amount as the initial drug amount in the mixing chamber.
[0007] As a preferred implementation of the present invention, the mixing maintenance unit collects the ambient temperature and calculates the mixing interference characteristic value according to the ambient temperature, and the mixing maintenance unit sends the mixing characteristic interference value to the mixing control unit.
[0008] As a preferred embodiment of the present invention, the drug-liquid separation unit is used to control the flow of drugs in the mixing chamber to the injection chamber. When the drug-liquid separation unit transfers the drugs through the mixing chamber to the injection chamber, the drug-liquid separation unit records the amount of drugs transferred and sends it to the mixing control unit. The mixing control unit calculates the difference between the initial amount of drugs and the amount of drugs transferred to obtain the remaining amount of drugs in the mixing chamber.
[0009] As a preferred embodiment of the present invention, after obtaining the mixing time, the mixing control unit analyzes the mixing time, the amount of medicine remaining in the mixing chamber and the mixing interference characteristic value through a formula to obtain the real-time mixing time, and the mixing control unit sends the real-time mixing time to the medicine-liquid separation unit.
[0010] As a preferred embodiment of the present invention, after the drug-liquid separation unit obtains the real-time mixing time, it multiplies the real-time mixing time and the drug-liquid injection speed to obtain the minimum storage volume of the drug-liquid.
[0011] As a preferred embodiment of the present invention, when the drug liquid separation unit transfers the drug liquid to the injection chamber through the mixing chamber, it controls the amount of drug existing in the injection chamber at the same time not to exceed the maximum storage capacity of the drug liquid. At the same time, before stirring, the mixing control unit obtains the real-time amount of drug liquid in the injection chamber, compares the real-time amount of drug liquid with the minimum storage capacity of drug liquid, and generates a mixing permission signal or a mixing non-permit signal based on the comparison result. The drug liquid is transferred from the mixing chamber to the injection chamber so that the drug liquid in the injection chamber is greater than the set minimum storage capacity of drug liquid, and then the mixing permission signal is generated.
[0012] As a preferred embodiment of the present invention, when the hybrid control unit collects the ambient temperature, a collection frequency is preset, and the collection frequency is the frequency of obtaining the temperature. The hybrid control unit obtains the characteristic interference value G in real time at the collection frequency, and obtains the real-time maintenance interval at the same frequency. The hybrid control unit obtains the inverse of the collection frequency and records it as the collection interval. After each real-time maintenance interval is obtained, the ratio of the collection interval to the real-time maintenance interval is calculated to obtain the equivalent interval ratio.
[0013] As a preferred embodiment of the present invention, the hybrid control unit calculates the equivalent interval ratio each time the real-time maintenance interval is obtained, and sums up all the equivalent interval ratios obtained by calculation, multiplies the summation result by the latest obtained real-time maintenance interval, and records the calculation result as the equivalent experienced time.
[0014] As a preferred embodiment of the present invention, the hybrid control unit obtains the set regular maintenance interval f, and calculates according to the hybrid characteristic interference value G and the regular maintenance interval f to obtain the real-time maintenance interval F. , where y is the set weight coefficient. Whenever the equivalent experience time reaches the real-time maintenance interval F, the mixing control unit performs a mixing operation on the medicine in the mixing chamber. The time of each mixing operation is the real-time mixing time.
[0015] A method for maintaining liquid mixing applied to a high-pressure contrast injection syringe comprises the following steps: Step 1: Calculate the maximum storage volume of the drug solution; Step 2: Calculate the initial drug volume and mixing time; Step 3: Calculate the real-time maintenance interval; Step 4: Control the storage volume of the drug solution; Step 5: Control the time for remixing the solution.
[0016] Compared with the prior art, the present invention has the following beneficial effects: 1. In the present invention, the contrast agent container is divided into a mixing chamber and an injection chamber. A small dose of liquid medicine is introduced into the injection chamber so that the liquid medicine in the injection chamber maintains the requirements for injection contrast. At the same time, the liquid medicine in the mixing chamber is analyzed according to the time experienced and the influence of the external environment temperature, and re-mixing is performed when the set indicators are reached, thereby ensuring that the liquid medicine in the mixing chamber is always maintained in a uniformly mixed state, ensuring the mixing uniformity of the contrast agent itself when the contrast agent is injected, and improving the contrast imaging effect.
[0017] 2. In the present invention, when the contrast agent is mixed again, the interference value is analyzed according to the ambient temperature, so that the time elapsed is equivalently accumulated according to the real-time environmental interference value, and the result of the equivalent accumulation is compared with the obtained mixing interval, so that when the temperature fluctuates, the impact of the changing temperature can be integrated and accumulated to ensure the scientific and effective mixing interval.
[0018] 3. In the present invention, when transferring the medicine liquid to the injection chamber, the upper limit of the constant temperature standing time of the medicine liquid and the time required for re-mixing in the mixing chamber are calculated in real time. Therefore, when the mixing chamber is re-mixing and cannot supply liquid to the injection chamber, it is ensured in advance that there is sufficient medicine liquid in the mixing chamber for injection. At the same time, the amount of medicine liquid in the injection chamber can be completely injected when the maximum standing time is reached, avoiding the situation where the mixing state of the medicine liquid in the injection chamber becomes uneven. BRIEF DESCRIPTION OF THE DRAWINGS
[0019] In order to facilitate understanding by those skilled in the art, the present invention is further described below with reference to the accompanying drawings.
[0020] Figure 1 is a system block diagram of the present invention; Figure 2 It is a system flow chart of the present invention. DETAILED DESCRIPTION
[0021] The technical scheme of the present invention will be described clearly and completely in conjunction with the embodiments below. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention. Embodiment 1:
[0022] See also Figure 1 - Figure 2 As shown, a drug liquid mixing and maintaining system applied to a high-pressure contrast injection syringe includes an injection control unit, a drug liquid analysis unit, a drug liquid separation unit, a mixing control unit, a drug amount input unit and a mixing maintaining unit; The injection control unit obtains the set injection speed by manual input and sends the injection speed to the liquid analysis unit; The drug liquid analysis unit obtains the drug liquid injection speed through the injection control unit, and calculates the drug liquid injection speed and the drug liquid standing time to obtain the maximum storage volume of the drug liquid, and sends the maximum storage volume of the drug liquid to the drug liquid separation unit, wherein the drug liquid standing time is the time when the drug liquid stands in a constant environment in the injection chamber, resulting in uneven distribution such as precipitation of the mixed drug again; The drug quantity input unit obtains the drug quantity entering the mixing chamber by manual input, and calculates the amount of solvent used for drug mixing according to the set mixing ratio, and obtains the mixing time by multiplying the amount of solvent by the set mixing diffusion speed, and sends the mixing time to the mixing control unit, which controls the stirring and mixing in the mixing chamber according to the mixing time, so that the stirring and mixing device operates according to the calculated mixing time, and records the amount of solvent as the initial drug quantity in the mixing chamber; The mixed maintenance unit collects the ambient temperature and calculates the mixed interference characteristic value through the ambient temperature. , where T is the ambient temperature, q is the preset weight coefficient, and the mixing maintenance unit sends the mixing characteristic interference value to the mixing control unit; The drug-liquid separation unit is used to control the flow of drugs in the mixing chamber to the injection chamber. When the drug-liquid separation unit transfers the drugs from the mixing chamber to the injection chamber, the transferred amount of drugs is recorded and sent to the mixing control unit. The mixing control unit calculates the difference between the initial amount of drugs and the amount of drugs transferred to obtain the remaining amount of drugs in the mixing chamber. After obtaining the mixing time, the mixing control unit records the mixing time as tm, and analyzes the real-time change value of the mixing time through formula analysis to obtain the real-time mixing time ts. , where k is the set weight coefficient, s is the amount of medicine remaining in the mixing chamber, G is the mixing interference characteristic value, and the mixing control unit sends the real-time mixing time to the drug-liquid separation unit; After the drug-liquid separation unit obtains the real-time mixing time, it multiplies the real-time mixing time and the drug-liquid injection speed to obtain the minimum storage volume of the drug-liquid; When the medicine liquid separation unit transfers the medicine liquid to the injection chamber through the mixing chamber, it controls the amount of medicine existing in the injection chamber at the same time not to exceed the maximum storage capacity of the medicine liquid. At the same time, the mixing control unit obtains the real-time amount of medicine liquid in the injection chamber before stirring, and compares the real-time amount of medicine liquid with the minimum storage capacity of medicine liquid. If the real-time amount of medicine liquid is greater than the minimum storage capacity of medicine liquid, a signal allowing mixing is generated; if the real-time amount of medicine liquid is less than or equal to the minimum storage capacity of medicine liquid, a signal not allowing mixing is generated, and the medicine liquid is transferred to the injection chamber through the mixing chamber so that the medicine liquid in the injection chamber is greater than the set minimum storage capacity of medicine liquid. Subsequently, a signal allowing mixing is generated to ensure that when the medicine liquid in the mixing chamber cannot be transferred to the injection chamber during the mixing maintenance period, there is sufficient medicine liquid in the injection chamber. Embodiment 2:
[0023] See also Figure 1 - Figure 2 As shown, the hybrid control unit obtains the set regular maintenance interval f, and calculates the real-time maintenance interval F according to the hybrid characteristic interference value G and the regular maintenance interval f. , where y is the set weight coefficient. Whenever the equivalent experience time reaches the real-time maintenance interval F, the mixing control unit performs a mixing operation on the medicine in the mixing chamber. The time of each mixing operation is the real-time mixing time. The method for the hybrid control unit to obtain the equivalent elapsed time is: When the hybrid control unit collects the ambient temperature, a collection frequency is preset, and the collection frequency is the frequency of obtaining the temperature. The hybrid control unit obtains the characteristic interference value G in real time at the collection frequency, and obtains the real-time maintenance interval at the same frequency; The hybrid control unit obtains the inverse of the acquisition frequency and records it as the acquisition interval, and after each acquisition of the real-time maintenance interval, calculates the ratio of the acquisition interval to the real-time maintenance interval to obtain an equivalent interval ratio; Each time the hybrid control unit obtains the real-time maintenance interval, it calculates the equivalent interval ratio, sums up all the equivalent interval ratios obtained by calculation, multiplies the summation result by the latest obtained real-time maintenance interval, and records the calculation result as the equivalent experienced time. Embodiment three:
[0024] See also Figure 1 - Figure 2 As shown, the liquid mixing and maintaining method applied to the high-pressure contrast injection syringe comprises the following steps: Step 1: Obtain the set rest time and injection speed, and calculate the maximum storage volume of the drug solution; Step 2: Calculate the amount of solvent by the amount of drug to obtain the initial amount of drug and mixing time; Step 3: Collect the ambient temperature in real time, obtain the real-time mixed interference characteristic value, and calculate the real-time maintenance interval according to the mixed interference characteristic value; Step 4: Calculate the minimum storage volume of the drug solution according to the real-time mixing time, and control the drug in the injection chamber according to the maximum storage volume of the drug solution and the minimum storage volume of the drug solution; Step 5: Calculate the remixing time of the drugs in the mixing chamber according to the real-time maintenance interval, and remix after the equivalent experience time reaches the real-time maintenance interval.
[0025] The preferred embodiments of the present invention disclosed above are only used to help explain the present invention. The preferred embodiments do not describe all the details in detail, nor do they limit the invention to only specific implementation methods. Obviously, many modifications and changes can be made according to the content of this specification. This specification selects and specifically describes these embodiments in order to better explain the principles and practical applications of the present invention, so that those skilled in the art can understand and use the present invention well. The present invention is limited only by the claims and their full scope and equivalents.
Claims
1. A liquid mixing and maintaining system for a high-pressure contrast injection syringe, characterized in that: The injection control unit includes an injection control unit, which collects the injection speed of the liquid medicine and generates a control signal according to the collected injection speed of the liquid medicine to control the injection speed of the liquid medicine; a liquid medicine analysis unit, wherein the liquid medicine analysis unit analyzes the injection time of the liquid medicine according to the injection speed of the liquid medicine, obtains the maximum liquid medicine storage volume, and sends the maximum liquid medicine storage volume to the liquid medicine separation unit; A drug-liquid separation unit, which can collect drug-liquid parameters in the mixing chamber and the injection chamber, and transfer the drug-liquid in the mixing chamber to the injection chamber; A medicine quantity input unit, which obtains the quantity of medicine entering the mixing chamber, generates a mixing time signal according to the obtained result, and sends the mixing time signal to the mixing control unit; A mixing control unit, which can control the mixing operation of the liquid medicine according to the mixing time signal, calculate the real-time mixing time and the real-time maintenance interval according to the environmental interference characteristic value, and re-mix the liquid medicine according to the real-time mixing time and the real-time maintenance interval; A hybrid maintenance unit, wherein the hybrid maintenance unit obtains a hybrid timing signal through a hybrid control unit, collects environmental information, performs collection and analysis based on hybrid interference items in the environmental information, and generates a hybrid interference characteristic value based on the collection and analysis results.
2. The liquid mixing and maintaining system for high-pressure contrast injection syringe according to claim 1, characterized in that: The injection control unit obtains the injection speed by manual input and sends the injection speed to the liquid analysis unit; The drug liquid analysis unit obtains the drug liquid injection speed through the injection control unit, calculates the drug liquid injection speed and the drug liquid standing time, obtains the maximum drug liquid storage volume, and sends the maximum drug liquid storage volume to the drug liquid separation unit.
3. The liquid mixing and maintaining system for high-pressure contrast injection syringe according to claim 1, characterized in that: The drug quantity input unit obtains the drug quantity entering the mixing chamber by manual input, and calculates the amount of solvent used for drug mixing according to the set mixing ratio, and obtains the mixing time by multiplying the solvent quantity by the set mixing diffusion speed, and sends the mixing time to the mixing control unit. The mixing control unit controls the stirring and mixing time in the mixing chamber according to the mixing time, and records the solvent quantity as the initial drug quantity in the mixing chamber.
4. The liquid mixing and maintaining system for high-pressure contrast injection syringe according to claim 1, characterized in that: The mixing maintenance unit collects the ambient temperature and calculates the mixing interference characteristic value according to the ambient temperature. The mixing maintenance unit sends the mixing characteristic interference value to the mixing control unit.
5. The liquid mixing and maintaining system for high-pressure contrast injection syringe according to claim 1, characterized in that: The drug-liquid separation unit is used to control the flow of drugs in the mixing chamber to the injection chamber. When the drug-liquid separation unit transfers the drugs through the mixing chamber to the injection chamber, the transferred amount of drugs is recorded and sent to the mixing control unit. The mixing control unit calculates the difference between the initial amount of drugs and the transferred amount of drugs to obtain the remaining amount of drugs in the mixing chamber.
6. The liquid mixing and maintaining system for high-pressure contrast injection syringe according to claim 5, characterized in that: After obtaining the mixing time, the mixing control unit analyzes the mixing time, the amount of medicine remaining in the mixing chamber and the mixing interference characteristic value through a formula to obtain the real-time mixing time, and sends the real-time mixing time to the medicine-liquid separation unit.
7. The liquid mixing and maintaining system for high-pressure contrast injection syringe according to claim 5, characterized in that: After obtaining the real-time mixing time, the drug-liquid separation unit calculates the product of the real-time mixing time and the drug-liquid injection speed to obtain the minimum storage volume of the drug-liquid.
8. The liquid mixing and maintaining system for high-pressure contrast injection syringe according to claim 7, characterized in that: When the drug liquid separation unit transfers the drug liquid to the injection chamber through the mixing chamber, it controls the amount of drug existing in the injection chamber at the same time so as not to exceed the maximum storage capacity of the drug liquid. At the same time, before stirring, the mixing control unit obtains the real-time amount of drug liquid in the injection chamber, compares the real-time amount of drug liquid with the minimum storage capacity of drug liquid, and generates a mixing permission signal or a mixing non-permitting signal based on the comparison result. The drug liquid is transferred from the mixing chamber to the injection chamber so that the drug liquid in the injection chamber is greater than the set minimum storage capacity of drug liquid, and then a mixing permission signal is generated.
9. The liquid mixing and maintaining system for high-pressure contrast injection syringe according to claim 1, characterized in that: When the hybrid control unit collects the ambient temperature, a collection frequency is preset, which is the frequency of obtaining the temperature. The hybrid control unit obtains the characteristic interference value G in real time at the collection frequency, and obtains the real-time maintenance interval at the same frequency. The hybrid control unit obtains the inverse of the collection frequency and records it as the collection interval. After each real-time maintenance interval is obtained, the ratio of the collection interval to the real-time maintenance interval is calculated to obtain the equivalent interval ratio.
10. The liquid mixing and maintaining system for high-pressure contrast injection syringe according to claim 9, characterized in that: The hybrid control unit calculates the equivalent interval ratio each time the real-time maintenance interval is obtained, sums all the equivalent interval ratios obtained by calculation, multiplies the summation result by the latest obtained real-time maintenance interval, and records the calculation result as the equivalent elapsed time.
11. The liquid mixing and maintaining system for high-pressure contrast injection syringe according to claim 10, characterized in that: The hybrid control unit obtains the set regular maintenance interval f, and calculates the real-time maintenance interval F according to the hybrid characteristic interference value G and the regular maintenance interval f. , where y is the set weight coefficient. Whenever the equivalent experience time reaches the real-time maintenance interval F, the mixing control unit performs a mixing operation on the medicine in the mixing chamber. The time of each mixing operation is the real-time mixing time.
12. A method for maintaining mixing of liquid medicine applied to a high-pressure contrast injection syringe, applicable to the system for maintaining mixing of liquid medicine applied to a high-pressure contrast injection syringe as claimed in claim 7, characterized in that: The method comprises the following steps: Step 1: Calculate the maximum storage volume of the drug solution; Step 2: Calculate the initial drug volume and mixing time; Step 3: Calculate the real-time maintenance interval; Step 4: Control the storage volume of the drug solution; Step 5: Control the time for remixing the solution.