Preparation method of pill traditional Chinese medicine composition

Abstract

The invention provides a preparation method of a pill traditional Chinese medicine composition, the pill traditional Chinese medicine composition is prepared by matching with a pill traditional Chinese medicine composition preparation device, and the preparation method comprises the following steps: preparing pill cores, feeding the pill cores into a pill forming part, and enabling the pill cores entering the pill forming part to sequentially pass through a plurality of groups of material adding seats I and material adding seats II; high-pressure coating powder and an atomized adhesive are input into the first material adding base and the second material adding base through a powder tank and an adhesive atomization assembly respectively, and multiple layers of coatings on the outer portions of pill cores are completed; according to the traditional Chinese medicine pellet coating device, traditional Chinese medicine pellets can be coated in the movement process, the requirement for the precision of the coating powder amount is met, after pellet cores enter a feeding sliding way, part of the pellet cores can fall into a feeding flow channel, the pellet cores are prevented from falling into the feeding flow channel, and the pellet cores are prevented from falling into the feeding flow channel. Gas containing a coating material is blown into the feeding runner and can be blown to the pellet core to move in the feeding slide way in a rotating posture, so that the coating material can be uniformly adhered to the outer part of the pellet core.

Description

Technical Field

[0001] The invention relates to the technical field of micro-pill preparation, in particular to a method for preparing a pill Chinese medicine composition. Background Art

[0002] Traditional Chinese medicine refers to medicines made from natural substances such as plants, animals, and minerals. In order to facilitate carrying and taking, Chinese medicinal materials are usually ground into powder and made into pills. Micropellets are spherical or quasi-spherical solid dosage forms with a diameter of 0.5 to 1.0 mm. They can also be loaded into capsules, pressed into tablets, or made into other preparations. Micropellets are a multi-unit oral dosage form. Usually, a single dose of medicine consists of dozens to hundreds of small pills. Different types of micropellets can be made, such as sustained-release, enteric-coated, etc. Common micropellet preparation processes include extrusion spheronization, hot-melt extrusion (spheronization), spherical agglomeration, condensation granulation, freeze-drying granulation, powder layering, etc.

[0003] A Chinese medicine pill-making machine disclosed in Chinese patent publication number CN202410910647.1 includes: a machine body and a mixing box arranged on the machine body, the mixing box is provided with a feed pipe and a discharge port, and a material extruder connected to the discharge port is arranged in the machine body; a pill-making mechanism is arranged in the machine body, the pill-making mechanism is connected to the discharge end of the material extruder; and a mixing mechanism for processing Chinese medicine. The machine body avoids the problem that most existing pill-making machines are relatively traditional, the material processing structure is simple, and it is difficult to ensure sufficient mixing of Chinese medicine, resulting in poor pill-making effect and serious impact on pill-making quality through the coordinated arrangement of the pill-making mechanism and the mixing mechanism.

[0004] Most existing preparation equipment forms pellets by mixing and rolling. However, for the production of Chinese medicine micro-pills, due to their tiny structure, even after the Chinese medicine powders are mixed, the accuracy of the ratio of each drug powder in each micro-pill cannot be guaranteed. At the same time, due to their small size, it is difficult to roll the pills, and more sophisticated pill rolling is required, which seriously reduces the preparation efficiency. Summary of the invention

[0005] 1. Technical issues to be resolved

[0006] In view of the deficiencies of the prior art, the present invention provides the following technical solution: a method for preparing a pill Chinese medicine composition, which is prepared by cooperating with a pill Chinese medicine composition preparation device, and comprises the following steps:

[0007] S1: prepare the pellet cores and send them into the pellet forming part. The pellet cores entering the pellet forming part will pass through several groups of feeding seats 1 and 2 in sequence.

[0008] S2: High-pressure coating powder and atomized adhesive are respectively input into the first and second feeding seats through the powder tank and the adhesive atomization assembly to complete several layers of coating on the outside of the pellet core;

[0009] S3: After preparation, the pills are inspected and packaged.

[0010] As a preferred embodiment of the present invention, the device for preparing the Chinese medicine composition in pill form comprises a pill forming part and a material part, and a driving component is installed on one side of the material part;

[0011] The pelletizing part comprises a support frame, one side of the support frame is provided with a feed channel, the other side of the support frame is provided with a discharge channel, and an equal number of feeding seats 1 and 2 are provided inside the support frame, and the feeding seats 1 and 2 are arranged in sequence;

[0012] The material part includes a mounting frame, and the mounting frame is provided with powder tanks whose number is equal to that of the feeding seat 1 and corresponds to each other. A discharge cavity and a powder cavity are sequentially provided inside the powder tank in the vertical direction, and the discharge cavity is separated from the powder cavity. A conveying assembly is installed inside the powder tank, and a vibrating filter plate is slidably connected inside the powder cavity. An adhesive atomization assembly is installed inside the feeding seat 1.

[0013] As a preferred embodiment of the present invention, one side of the feeding seat is provided with several groups of feeding chutes which are arranged through the feeding seat, and a feed channel and a discharge channel are provided inside the feeding seat, and the feed channel is connected with the bottom of the several groups of feeding chutes. When the ball core is inside the feeding chute, 1 / 3 of its area extends into the feed channel.

[0014] As a preference of this embodiment, the feed channel is communicated with an end of the discharge channel, and the other end of the feed channel and the discharge channel is communicated with the corresponding powder tank.

[0015] As a preferred embodiment of the present invention, a plurality of guide grooves are provided on one side of the second adding seat, a docking groove is provided on one side of the second adding seat, an aerosol flow channel is provided inside the second adding seat, a plurality of air holes connected to the guide grooves are provided at the bottom of the aerosol flow channel, and the aerosol flow channel is connected to the output end of the adhesive atomization assembly.

[0016] As a preferred embodiment of this embodiment, the feeding slide and the guide groove are both inclined, the inclination height difference of the guide groove is at most half of the inclination height difference of the feeding slide, and the docking groove is connected to the lowest point of the guide groove.

[0017] As a preferred embodiment of this embodiment, the conveying assembly includes a main shaft and a sleeve, one end of the main shaft is fixedly connected with a meshing tooth, a conveying dragon is installed on the outside of the main shaft, one end of the sleeve adjacent to the meshing tooth is fixedly connected to the outside of the main shaft, and the other end of the sleeve is fixedly connected to the outside of the slow-speed filter plate.

[0018] As a preference of this embodiment, the discharge chamber is communicated with the feed channel, the powder chamber is communicated with the discharge channel, and a discharge groove is formed outside the area where the sleeve is arranged inside the discharge chamber.

[0019] As a preferred embodiment of this embodiment, a lifting groove is provided on the upper end surface of the slow filter plate, and a plurality of lifting blocks are fixedly connected inside the lifting groove. At least one group of support columns is fixedly connected to the lower end surface of the vibration filter plate, and the support columns are slidably connected inside the lifting groove.

[0020] As a preference of this embodiment, the driving assembly includes a driving motor, an output end of the driving motor is fixedly connected to a rotating shaft, a bevel gear is arranged outside the rotating shaft, and the bevel gear meshes with the meshing teeth.

[0021] (II) Beneficial effects

[0022] The present invention provides a method for preparing a pill Chinese medicine composition, which has the following beneficial effects:

[0023] The present invention uses a plurality of groups of feeding seats 1 and 2 arranged in sequence, so that the Chinese medicine micro-pills can be coated during movement, and the coating powder is formed on the outside of the pill core in an adhered manner, which can ensure the accuracy of the amount of coating powder. After the pill core enters the inside of the feeding chute, a part of the area will fall into the inside of the feeding flow channel. By blowing the gas containing the coating material into the inside of the feeding flow channel, the pill core can be blown to move in the inside of the feeding chute in a rotating posture, so that the coating material can be evenly adhered to the outside of the pill core.

[0024] At the same time, after the pills enter the guide groove, the guide groove gradually rises along the moving direction, which can reduce the flow speed of the pills, and the atomized adhesive enters the guide groove through the air vents and adheres to the surface of the pills. In addition, the pills will compact the coating material adhered to the inside of the feeding slideway during the movement, thereby ensuring that the preparation of the pills can be completed after passing through the first and second feeding seats, effectively improving the preparation efficiency.

[0025] In addition, the coated powder is inside the powder chamber and needs to be filtered twice by the vibrating filter plate and the slow-speed filter plate before entering the conveying position of the conveying dragon, ensuring the fineness of the powder conveyed to the discharge chamber. When the main shaft rotates, the support column will slowly rise and then fall instantly when passing through the lifting block, ensuring that there is sufficient coating powder to be conveyed. BRIEF DESCRIPTION OF THE DRAWINGS

[0026] Figure 1 It is a flow chart of the preparation method of the pill Chinese medicine composition of the present invention;

[0027] Figure 2 This is a schematic diagram of the structure of the device for preparing the pill Chinese medicine composition of the present invention;

[0028] Figure 3 It is a schematic diagram of the structure of the pill-forming part of the present invention;

[0029] Figure 4 This is a schematic cross-sectional structural diagram of a material adding seat according to the present invention;

[0030] Figure 5 This is a schematic cross-sectional view of the structure of the second material adding seat of the present invention;

[0031] Figure 6 It is a schematic diagram of the material part structure of the present invention;

[0032] Figure 7 This is a schematic diagram of the internal structure of the powder tank of the present invention;

[0033] Figure 8 It is a schematic diagram of the structure of the conveying assembly of the present invention;

[0034] Fig. 9 for Figure 8 A magnified view of the structure;

[0035] Fig.10 It is a schematic diagram of the fixed disk structure of the present invention.

[0036] In the figure: 100 pill forming unit, 101 feeding seat 1, 102 feeding seat 2, 103 feeding slide, 104 feed flow channel, 105 discharge flow channel, 106 aerosol flow channel, 107 guide groove, 108 docking groove, 200 material unit, 201 powder tank, 202 adhesive atomization component, 203 discharge chamber, 204 powder chamber, 205 conveying component, 206 vibrating filter plate, 207 sleeve, 208 meshing teeth, 209 discharge groove, 210 slow filter plate, 211 conveying dragon, 212 lifting groove, 213 lifting block, 300 driving component, 301 driving motor, 302 rotating shaft. DETAILED DESCRIPTION

[0037] The embodiments of the present invention are described in detail below, examples of which are shown in the accompanying drawings, wherein the same or similar reference numerals throughout represent the same or similar elements or elements having the same or similar functions. The embodiments described below with reference to the accompanying drawings are exemplary and are only used to explain the present invention, and cannot be understood as limiting the present invention.

[0038] In the description of the present invention, it should be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", "clockwise", "counterclockwise" and the like indicate positions or positional relationships based on the positions or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as limiting the present invention. In addition, the terms "first" and "second" are only used for descriptive purposes, and cannot be understood as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Therefore, the features defined as "first" and "second" may explicitly or implicitly include one or more features. In the description of the present invention, the meaning of "multiple" is two or more, unless otherwise clearly and specifically defined.

[0039] In the description of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "installed", "connected", and "connected" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection, an electrical connection, or mutual communication; it can be a direct connection, or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0040] In the present invention, unless otherwise clearly specified and limited, a first feature being "above" or "below" a second feature may include that the first and second features are in direct contact, or may include that the first and second features are not in direct contact but are in contact through another feature between them. Moreover, a first feature being "above", "above" and "above" a second feature includes that the first feature is directly above and obliquely above the second feature, or simply indicates that the first feature is higher in level than the second feature. A first feature being "below", "below" and "below" a second feature includes that the first feature is directly below and obliquely below the second feature, or simply indicates that the first feature is lower in level than the second feature.

[0041] The disclosure below provides many different embodiments or examples to realize different structures of the present invention. In order to simplify the disclosure of the present invention, the parts and settings of specific examples are described below. Of course, they are only examples, and the purpose is not to limit the present invention. In addition, the present invention can repeat reference numbers and / or reference letters in different examples, and this repetition is for the purpose of simplicity and clarity, which itself does not indicate the relationship between the various embodiments and / or settings discussed. In addition, the present invention provides various specific examples of processes and materials, but those of ordinary skill in the art can be aware of the application of other processes and / or the use of other materials.

[0042] like Figure 1 As shown, this embodiment provides a method for preparing a Chinese medicine composition in the form of a pill, which is used for making Chinese medicine micro-pellets, the particle size of which is 1-5 mm, and is prepared by a Chinese medicine composition preparation device in the form of a pill, comprising the following steps:

[0043] S1: preparing pellet cores and feeding the pellet cores into the pellet forming unit 100. The pellet cores entering the pellet forming unit 100 will pass through a plurality of groups of feeding seats 1 101 and feeding seats 2 102 in sequence;

[0044] S2: High-pressure coating powder and atomized adhesive are respectively input into the feeding seat 1 101 and the feeding seat 2 102 through the powder tank 201 and the adhesive atomization assembly 202 to complete several layers of coating on the outside of the pellet core;

[0045] S3: After preparation, the pills are inspected and packaged.

[0046] like Figure 2-6 As shown, the device for preparing a pill Chinese medicine composition comprises a pill forming part 100 and a material part 200, and a driving component 300 is installed on one side of the material part 200;

[0047] The pelletizing unit 100 includes a support frame, a feeding slide is installed on one side of the support frame, a discharging slide is installed on the other side, and an equal number of feeding seats 101 and feeding seats 2 102 are installed inside, and the feeding seats 101 and the feeding seats 2 102 are arranged in sequence;

[0048] There are at least one group of the first adding seat 101 and the second adding seat 102, and the feed port of the first group of the first adding seat 101 is connected to the feed chute, and the discharge port of the last group of the second adding seat 102 is connected to the discharge chute.

[0049] The material section 200 includes a mounting frame, inside which powder tanks 201 are arranged in the same number as the feeding seat 101, and correspond one to one. A discharge chamber 203 and a powder chamber 204 are arranged in sequence along the vertical direction inside the powder tank 201, and the discharge chamber 203 is separated from the powder chamber 204. A conveying assembly 205 is installed inside the powder tank 201, and a vibrating filter plate 206 is slidably connected inside the powder chamber 204. An adhesive atomization assembly 202 is installed inside the feeding seat 101.

[0050] like Figure 4 As shown, one side of the feeding seat 101 is provided with a plurality of groups of feeding slides 103 which are arranged through the feeding seat 101, and a feeding channel 104 and a discharging channel 105 are provided inside the feeding seat 101. The feeding channel 104 is connected with the bottom of the plurality of groups of feeding slides 103. When the pellet core is inside the feeding slide 103, 1 / 3 of its area extends into the feed channel 104.

[0051] Specifically, after the ball core enters the feeding chute 103, part of the area will fall into the feeding channel 104. By blowing the coating material-containing gas into the feeding channel 104, the ball core can be blown to move in the feeding chute 103 in a rotating posture, so that the coating material can be evenly adhered to the outside of the ball core.

[0052] Furthermore, the end of the feed channel 104 is connected to the end of the discharge channel 105 , and the other end of the feed channel 104 and the discharge channel 105 is connected to the corresponding powder tank 201 .

[0053] like Figure 5 As shown, a plurality of guide grooves 107 are provided on one side of the second adding seat 102, a docking groove 108 is provided on one side of the second adding seat 102, an aerosol flow channel 106 is provided inside the second adding seat 102, a plurality of air holes connected to the guide grooves 107 are provided at the bottom of the aerosol flow channel 106, and the aerosol flow channel 106 is connected to the output end of the adhesive atomization assembly 202.

[0054] Furthermore, the material adding slide 103 and the guide groove 107 are both inclined, and the height difference of the guide groove 107 is at most half of the height difference of the material adding slide 103 , and the docking groove 108 is connected to the lowest point of the guide groove 107 .

[0055] It should be noted that the docking groove 108 is opened on the side of the feeding seat 102 adjacent to the feed channel, and the pills discharged from the feeding seat 101 will enter the guide groove 107 through the docking groove 108, and the lowest point of the guide groove 107 is not higher than the lowest point of the feeding slide 103.

[0056] Specifically, after the pills enter the guide groove 107, the guide groove 107 gradually rises along the direction of movement, which can reduce the flow speed of the pills, and the atomized adhesive enters the guide groove 107 through the air holes and adheres to the surface of the pills. In the process of movement, the pills will compact the coating material adhered to the inside of the feeding slide 103.

[0057] The atomized adhesive is in an atomized state, and is a mixture of honey and water. The atomized adhesive can also promote the movement of the pills to prevent the pills from flowing back.

[0058] like Figure 7-9 As shown, the conveying assembly 205 includes a main shaft and a sleeve 207, one end of the main shaft is fixedly connected with a meshing tooth 208, a conveying dragon 211 is installed on the outside of the main shaft, one end of the sleeve 207 adjacent to the meshing tooth 208 is fixedly connected to the outside of the main shaft, and the other end of the sleeve 207 is fixedly connected to the outside of the slow-speed filter plate 210.

[0059] Furthermore, the discharge chamber 203 is communicated with the feed channel 104 , the powder chamber 204 is communicated with the discharge channel 105 , and the sleeve 207 is disposed in an area inside the discharge chamber 203 and has a discharge groove 209 outside.

[0060] Furthermore, a lifting groove 212 is provided on the upper end surface of the slow filter plate 210, and a plurality of lifting blocks 213 are fixedly connected inside the lifting groove 212. At least one group of support columns is fixedly connected to the lower end surface of the vibration filter plate 206, and the support columns are slidably connected inside the lifting groove 212.

[0061] Specifically, the coated powder is inside the powder chamber 204, and the coated powder needs to be filtered twice by the vibrating filter plate 206 and the slow filter plate 210 before entering the conveying position of the conveying dragon 211, ensuring the fineness of the powder conveyed to the discharge chamber 203. When the main shaft rotates, the support column will slowly rise and then fall instantly when passing through the lifting block 213, ensuring that there is sufficient coating powder to be conveyed.

[0062] It should be noted that the powder cavity 204 is connected to the output end of the induced draft fan through an air pipe, and the input end of the induced draft fan is connected to the discharge channel 105.

[0063] like Fig.10 As shown, the driving assembly 300 includes a driving motor 301 , the output end of the driving motor 301 is fixedly connected to a rotating shaft 302 , a bevel gear is disposed outside the rotating shaft 302 , and the bevel gear is meshed with the meshing teeth 208 .

[0064] The coating processing equipment provided by the present invention: through a plurality of groups of feeding seats 101 and 102 arranged in sequence, the Chinese medicine micro-pills can be coated during movement, and the coating powder is formed on the outside of the pellet core in an adhered manner, which can ensure the accuracy of the amount of coating powder. After the pellet core enters the inside of the feeding chute 103, a part of the area will fall into the inside of the feeding flow channel 104. By blowing the gas containing the coating material into the inside of the feeding flow channel 104, the pellet core can be blown to move in the inside of the feeding chute 103 in a rotating posture, so that the coating material can be evenly adhered to the outside of the pellet core;

[0065] At the same time, after the pills enter the guide groove 107, the guide groove 107 gradually rises along the moving direction, which can reduce the flow speed of the pills, and the atomized adhesive enters the guide groove 107 through the air holes and adheres to the surface of the pills, and the pills will compact the coating material adhered to the inside of the feeding slide 103 during the movement, thereby ensuring that the preparation of the pills can be completed after passing through the first and second feeding seats, effectively improving the preparation efficiency;

[0066] In addition, the coated powder is inside the powder chamber 204, and the coated powder needs to be filtered twice by the vibrating filter plate 206 and the slow filter plate 210 before entering the conveying position of the conveying dragon 211, ensuring the fineness of the powder conveyed to the discharge chamber 203. When the main shaft rotates, the support column will slowly rise and then fall instantly when passing through the lifting block 213, ensuring that there is sufficient coating powder to be conveyed.

[0067] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A method for preparing a pill Chinese medicine composition, which is prepared by cooperating with a pill Chinese medicine composition preparation device, characterized in that: The following steps are involved: S1: prepare the pellet cores and send them into the pellet forming part. The pellet cores entering the pellet forming part will pass through several groups of feeding seats 1 and 2 in sequence. S2: High-pressure coating powder and atomized adhesive are respectively input into the first and second feeding seats through the powder tank and the adhesive atomization assembly to complete several layers of coating on the outside of the pellet core; S3: After preparation, the pills are inspected and packaged.

2. The method for preparing a pill Chinese medicine composition according to claim 1, characterized in that: The device for preparing a pill-shaped Chinese medicine composition comprises a pill-forming part and a material part, and a driving component is installed on one side of the material part; The pelletizing part comprises a support frame, one side of the support frame is provided with a feed channel, the other side of the support frame is provided with a discharge channel, and an equal number of feeding seats 1 and 2 are provided inside the support frame, and the feeding seats 1 and 2 are arranged in sequence; The material part includes a mounting frame, and the mounting frame is provided with powder tanks whose number is equal to that of the feeding seat 1 and corresponds to each other. A discharge cavity and a powder cavity are sequentially provided inside the powder tank in the vertical direction, and the discharge cavity is separated from the powder cavity. A conveying assembly is installed inside the powder tank, and a vibrating filter plate is slidably connected inside the powder cavity. An adhesive atomization assembly is installed inside the feeding seat 1.

3. The method for preparing a pill Chinese medicine composition according to claim 1, characterized in that: One side of the feeding seat is provided with several groups of feeding slides which are arranged through the feeding seat, and the inside of the feeding seat is provided with a feed channel and a discharge channel. The feed channel is connected with the bottom of the several groups of feeding slides. When the ball core is inside the feeding slide, 1 / 3 of its area extends into the inside of the feed channel.

4. The method for preparing a pill Chinese medicine composition according to claim 1, characterized in that: The feed channel is communicated with an end of the discharge channel, and the other ends of the feed channel and the discharge channel are communicated with the corresponding powder tank.

5. The method for preparing a pill Chinese medicine composition according to claim 1, characterized in that: A plurality of guide grooves are provided on one side of the second adding seat, a docking groove is provided on one side of the second adding seat, an aerosol flow channel is provided inside the second adding seat, a plurality of air holes connected to the guide grooves are provided at the bottom of the aerosol flow channel, and the aerosol flow channel is connected to the output end of the adhesive atomization component.

6. The method for preparing a pill Chinese medicine composition according to claim, characterized in that: The material-feeding slideway and the guide groove are both arranged at an inclination, and the inclination height difference of the guide groove is at most half of the inclination height difference of the material-feeding slideway, and the docking groove is connected to the lowest point of the guide groove.

7. The method for preparing a pill Chinese medicine composition according to claim 1, characterized in that: The conveying assembly includes a main shaft and a sleeve, one end of the main shaft is fixedly connected with a meshing tooth, a conveying dragon is installed on the outside of the main shaft, one end of the sleeve adjacent to the meshing tooth is fixedly connected to the outside of the main shaft, and the other end of the sleeve is fixedly connected to the outside of a slow-speed filter plate.

8. The method for preparing a pill Chinese medicine composition according to claim, characterized in that: The discharge cavity is communicated with the feed channel, the powder cavity is communicated with the discharge channel, and a discharge groove is formed outside the area where the sleeve is arranged inside the discharge cavity.

9. The method for preparing a pill Chinese medicine composition according to claim, characterized in that: The upper end surface of the slow filter plate is provided with a lifting groove, and a plurality of lifting blocks are fixedly connected inside the lifting groove. The lower end surface of the vibration filter plate is fixedly connected with at least one group of support columns, and the support columns are slidably connected inside the lifting groove.

10. The method for preparing a pill Chinese medicine composition according to claim, characterized in that: The driving assembly comprises a driving motor, an output end of the driving motor is fixedly connected to a rotating shaft, a bevel gear is arranged outside the rotating shaft, and the bevel gear is meshed with the meshing teeth.

Images