Sampling equipment for biological medicine

By designing sealing components and driving components in biomedical sampling equipment, the problems of drug liquid leakage and rotation direction control are solved, and efficient and reliable drug liquid transmission and the adaptation of complex sampling processes are achieved.

CN119666473APending Publication Date: 2025-03-21厦门海万生物科技有限公司
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Patent Information

Application Number
CN202411867922.2
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-12-18
Publication Date
2025-03-21

AI Technical Summary

Technical Problem

Existing biomedical sampling equipment is prone to leakage of medicine after sampling is completed, and it lacks flexible control of the rotation direction of the extrusion roller, resulting in frequent manual intervention in the complex sampling process, affecting efficiency.

Method used

A biomedical sampling device including a peristaltic pump body and a sampling mechanism is designed. The sealing assembly ensures that the interface between the hose and the sampling bag is closely connected, and is automatically closed after sampling is completed to prevent leakage of the drug liquid. The combination of the drive assembly, guide assembly and positioning assembly provides power and flexible adjustment of the rotation direction of the turntable and extrusion roller to avoid deviation of the rotation direction.

Benefits of technology

It prevents the leakage of the medicine liquid during the sampling process, and adapts to the complex sampling process without complex debugging, improving the efficiency and reliability of the equipment.

✦ Generated by Eureka AI based on patent content.

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Abstract

The invention relates to the technical field of pharmaceutical engineering, and discloses biomedical sampling equipment which comprises a mounting box, a hose fixedly connected to the inner surface of the mounting box, and a turntable arranged in an inner cavity of the mounting box, the sampling mechanism comprises a sealing assembly which is matched with the hose to prevent liquid medicine leakage in the sampling process, a mounting frame which is fixedly connected to the outer surface of the mounting box, a driving assembly which is matched with and drives the extrusion roller to extrude the hose, and a guide assembly which is matched with and changes the extrusion direction of the extrusion roller. By means of the sealing assembly, it can be ensured that the connector of the hose and the connector of the sampling bag are tightly connected in the sampling process, and the connector of the hose and the connector of the sampling bag can be automatically closed after sampling is completed; through direct cooperation of all parts in the driving assembly, the guiding assembly and the positioning assembly, rotating power can be provided for the rotating disc and the extrusion roller, the rotating direction of the rotating disc and the extrusion roller can be flexibly adjusted, and deviation of the rotating direction of the rotating disc and the extrusion roller is effectively prevented.
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Description

Technical Field

[0001] The invention relates to the technical field of pharmaceutical engineering, and in particular to a sampling device for biomedicine. Background Art

[0002] In recent years, sampling equipment for biomedicine has indeed made significant technological progress. Peristaltic Pump, as a common liquid medicine transmission device, is increasingly widely used in various sampling tasks in modern laboratories. Peristaltic pumps transmit liquid medicine by squeezing soft pipes. Its working principle is based on "peristaltic" action, that is, a series of rollers or pressure blocks move along the pipe to push the liquid medicine forward. Because the liquid medicine only contacts the inside of the pipe and will not contact other parts of the pump, cross contamination can be effectively avoided. Only the pipe needs to be replaced, which is simple to maintain and suitable for processing different types of samples.

[0003] After sampling is completed, some peristaltic pumps in the prior art usually have the problem of easy leakage of drug solution due to the lack of sealing mechanism at the interface between the hose and the sampling container. The leakage of drug solution may cause the sample to contact with the external environment, introduce impurities or pollutants, and affect the accuracy of the experimental results. Some peristaltic pumps can usually only realize basic start and stop and speed adjustment functions, and lack the ability to control the rotation direction of the extrusion roller. In some complex sampling processes, such as collecting samples from different containers and transmitting them to different analytical instruments respectively, the peristaltic pump that lacks bidirectional rotation function will increase the frequency and complexity of manual intervention by the user. Although the use of servo motors can flexibly control the rotation direction of the peristaltic pump, the servo motor is more dependent on the closed-loop control system, and the parameters need to be precisely adjusted to ensure the stability and response speed of the system. Debugging is usually time-consuming, which may greatly reduce the efficiency of the sampling work. Summary of the invention

[0004] In view of the above problems existing in the existing biomedical sampling equipment, the present invention is proposed.

[0005] Therefore, an object of the present invention is to provide a sampling device for biomedicine.

[0006] In order to solve the above technical problems, the present invention provides the following technical solutions: comprising:

[0007] The peristaltic pump body comprises a mounting box, a hose fixedly connected to the inner surface of the mounting box, a turntable arranged in the inner cavity of the mounting box, and extrusion rollers fixedly mounted on the inner walls of both sides of the turntable through bearings;

[0008] The sampling mechanism includes a sealing component used in conjunction with the hose to prevent leakage of liquid medicine during the sampling process, a mounting frame fixedly connected to the outer surface of the mounting box, a driving component used in conjunction with driving the squeezing roller to squeeze the hose, a guiding component used in conjunction with changing the squeezing direction of the squeezing roller, and a positioning component used in conjunction with fixing the conduction direction of the guiding component.

[0009] As a preferred solution of the biomedical sampling device of the present invention, both ends of the hose extend to the outside of the installation box, and the outer surface of the squeezing roller is in sliding contact with the outer surface of the hose.

[0010] As a preferred embodiment of the biomedical sampling device described in the present invention, the sealing assembly includes a connecting tube connected to the inner cavity of the hose, a sliding sleeve slidably mounted on the outer surface of the connecting tube, a first spring mounted on the outer surface of the connecting tube and used in conjunction with the sliding sleeve, a second spring fixedly mounted on the inner wall of the connecting tube, a first hollow plug fixedly connected to the other end of the second spring, and a plurality of balls distributed in a circular array in the inner cavity of the connecting tube.

[0011] As a preferred solution of the biomedical sampling device described in the present invention, the sealing assembly also includes a plug-in tube arranged on the outside of the connecting tube, a third spring fixedly installed on the inner wall of the plug-in tube, a second hollow plug fixedly connected to the other end of the third spring and used in conjunction with the first hollow plug, a groove opened on the outside of the plug-in tube and used in conjunction with the ball, and a sampling bag connected to the inner cavity of the plug-in tube and used in conjunction with the hose.

[0012] As a preferred solution of the biomedical sampling device described in the present invention, the driving assembly includes a fixing plate fixedly connected to the bottom of the mounting frame, a motor adapted to be mounted on the top of the fixing plate, a driving column fixedly mounted on the output end of the motor through a coupling, a first pulley fixedly mounted on the outer surface of the driving column, a belt mounted on the outer surface of the first pulley, a second pulley mounted on the inner surface of the other end of the belt, a driven column fixedly connected to the outer end surface of the second pulley, a driving gear fixedly mounted on the through end of the driven column, and a driven gear meshed with the outer surface of the driving gear.

[0013] As a preferred solution of the biomedical sampling device of the present invention, the driving gear and the driven gear are both located on the inner side of the mounting frame, and the outer end surfaces of the driving gear and the driven gear are fixedly mounted on the inner wall of the mounting frame through bearings.

[0014] As a preferred embodiment of the biomedical sampling device described in the present invention, the guide assembly includes a fixed sleeve fixedly connected to the outer surface of the fixed plate, a rotating shaft in rotational contact with the inner wall of the fixed sleeve, a swing block fixedly sleeved on the outer surface of the rotating shaft, a support shaft in rotational contact with the inner surface of the swing block, a guide gear and a synchronous gear respectively fixedly sleeved on both side surfaces of the support shaft, a transmission gear meshed with the outer surface of the synchronous gear, and a transmission shaft fixedly connected to the inner surface of the transmission gear and used in conjunction with the turntable.

[0015] As a preferred solution of the biomedical sampling device described in the present invention, the outer end surface of the rotating shaft is fixedly mounted on the outer surface of the mounting frame through a bearing, the through end of the transmission shaft is fixedly connected to the outer surface of the turntable, and a bearing sleeve for matching rotation is installed at the connection between the transmission shaft and the mounting box.

[0016] As a preferred solution of the biomedical sampling device described in the present invention, the positioning component includes a knob slidably mounted on the outer surface of the rotating shaft, a fixing column fixedly connected to the outer surface of the knob, a groove opened on the outer surface of the fixing sleeve and used in conjunction with the fixing column, and a fourth spring mounted on the outer surface of the rotating shaft and used in conjunction with the knob.

[0017] As a preferred solution of the biomedical sampling device of the present invention, the outer surface of the knob is movably connected to the inner wall of the fixed sleeve, and the fourth spring is located inside the fixed sleeve.

[0018] The beneficial effects of the present invention are as follows: through the sealing component, not only can the interface of the hose and the sampling bag be ensured to be tightly connected during the sampling process, but also the interface of the hose and the sampling bag can be automatically sealed after the sampling is completed, so as to avoid leakage of the liquid medicine while ensuring the safety and reliability of the liquid medicine transmission; through the direct cooperation of the components in the driving component, the guide component and the positioning component, not only can the turntable and the extrusion roller be provided with rotational power, but also the rotation direction of the turntable and the extrusion roller can be flexibly adjusted, and the rotation direction of the turntable and the extrusion roller can be effectively prevented from being offset, so as to achieve the effect that the peristaltic pump body can adapt to more complex sampling processes without the need for complex debugging. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the following briefly introduces the drawings required for describing the embodiments. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without creative work. Among them:

[0020] Figure 1It is a schematic diagram of the overall structure of the present invention.

[0021] Figure 2 For the present invention Figure 1 A schematic diagram of the enlarged structure of the local area in the middle.

[0022] Figure 3 It is a schematic diagram of the structure inside the sealing component of the present invention.

[0023] Figure 4 It is a structural schematic diagram of another viewing angle of the present invention as a whole.

[0024] Figure 5 For the present invention Figure 4 Schematic diagram of the enlarged structure of the local area B in the middle.

[0025] Figure 6 This is a structural schematic diagram of the peristaltic pump body in the present invention from another perspective.

[0026] Figure 7 It is a schematic diagram of the overall structure of the positioning component in the present invention.

[0027] In the figure: 100, peristaltic pump body; 101, installation box; 102, hose; 103, turntable; 104, squeeze roller; 200, sampling mechanism; 201, sealing assembly; 201a, connecting pipe; 201b, sliding sleeve; 201c, first spring; 201d, second spring; 201e, first hollow plug; 201f, ball; 201g, plug-in tube; 201h, third spring; 201i, second hollow plug; 201j, groove; 201k, sampling bag; 202, installation frame; 203, drive assembly; 203a, fixing plate; 203b, Motor; 203c, driving column; 203d, first pulley; 203e, belt; 203f, second pulley; 203g, driven column; 203h, driving gear; 203i, driven gear; 204, guide assembly; 204a, fixed sleeve; 204b, rotating shaft; 204c, swing block; 204d, supporting shaft; 204e, guide gear; 204f, synchronous gear; 204g, transmission gear; 204h, transmission shaft; 205, positioning assembly; 205a, knob; 205b, fixed column; 205c, M-shaped groove; 205d, fourth spring. DETAILED DESCRIPTION

[0028] In order to make the above-mentioned objects, features and advantages of the present invention more obvious and easy to understand, the specific implementation methods of the present invention are described in detail below in conjunction with the accompanying drawings.

[0029] In the following description, many specific details are set forth to facilitate a full understanding of the present invention, but the present invention may also be implemented in other ways different from those described herein, and those skilled in the art may make similar generalizations without violating the connotation of the present invention. Therefore, the present invention is not limited to the specific embodiments disclosed below.

[0030] Secondly, the term "one embodiment" or "embodiment" as used herein refers to a specific feature, structure, or characteristic that may be included in at least one implementation of the present invention. The term "in one embodiment" that appears in different places in this specification does not necessarily refer to the same embodiment, nor does it refer to a separate or selective embodiment that is mutually exclusive with other embodiments.

[0031] Secondly, the present invention is described in detail with reference to the schematic diagram. When describing the embodiments of the present invention in detail, for the sake of convenience, the cross-sectional diagrams showing the device structure will not be partially enlarged according to the general scale, and the schematic diagrams are only examples, which should not limit the scope of protection of the present invention. In addition, in actual production, the three-dimensional dimensions of length, width and depth should be included.

[0032] Example 1

[0033] Reference Figure 1 to Figure 3 , as a first embodiment of the present invention, provides a sampling device for biomedicine, the device comprising:

[0034] The peristaltic pump body 100 includes a mounting box 101, a hose 102 fixedly connected to the inner surface of the mounting box 101, a turntable 103 disposed in the inner cavity of the mounting box 101, and squeezing rollers 104 fixedly mounted on the inner walls of both sides of the turntable 103 through bearings;

[0035] It should be noted that the mounting box 101 is the basic structure of the peristaltic pump body 100, which is used to accommodate and fix all other components. It ensures that the peristaltic pump body 100 remains stable during operation by providing mechanical support and protects the internal components from the influence of the external environment. The hose 102 serves as a transmission channel for the liquid medicine. It adopts PVC material with good elasticity and strong resistance to chemical corrosion. It can quickly return to its original state after being squeezed to ensure the continuous transmission of the liquid medicine. The turntable 103 is responsible for driving the squeezing roller 104 to rotate, so that the squeezing roller 104 can realize the transmission of the liquid medicine by periodically compressing the hose 102. The working principle of the squeezing roller 104 is based on the "peristaltic" action, that is, a series of squeezing rollers 104 move along the hose 102 to provide power for the turntable 103 and the squeezing roller 104. This is a prior art, and this scheme will not be described in detail, and personnel in this technical field can clearly understand its working principle.

[0036] The sampling mechanism 200 includes a sealing component 201 used in conjunction with the hose 102 to prevent leakage of the liquid medicine during the sampling process, a mounting frame 202 fixedly connected to the outer surface of the mounting box 101, a driving component 203 used in conjunction with the driving squeezing roller 104 to extrude the hose 102, a guide component 204 used in conjunction with changing the squeezing direction of the squeezing roller 104, and a positioning component 205 used in conjunction with fixing the conduction direction of the guide component 204.

[0037] It should be noted that the sealing component 201 can not only ensure that the interface between the hose 102 and the sampling bag 201k is tightly connected during the sampling process, but also automatically seal the interface between the hose 102 and the sampling bag 201k after the sampling is completed, thereby avoiding leakage of the liquid medicine. The mounting frame 202 is used to provide stable support for the driving component 203 and the guide component 204. The driving component 203 is used to provide power for the turntable 103 and the squeezing roller 104 to achieve the transportation of the liquid medicine. The guide component 204 can flexibly adjust the rotation direction of the turntable 103 and the squeezing roller 104 without debugging. The positioning component 205 is used to fix the rotation direction of the turntable 103 and the squeezing roller 104 to avoid failure of the sampling work due to the deviation of the rotation direction of the turntable 103 and the squeezing roller 104.

[0038] Specifically, both ends of the hose 102 extend to the outside of the installation box 101 , and the outer surface of the squeezing roller 104 is in sliding contact with the outer surface of the hose 102 .

[0039] Furthermore, the sealing assembly 201 includes a connecting tube 201a connected to the inner cavity of the hose 102, a sliding sleeve 201b slidably mounted on the outer surface of the connecting tube 201a, a first spring 201c mounted on the outer surface of the connecting tube 201a and used in conjunction with the sliding sleeve 201b, a second spring 201d fixedly mounted on the inner wall of the connecting tube 201a, a first hollow plug 201e fixedly connected to the other end of the second spring 201d, and a plurality of balls 201f distributed in a circular array in the inner cavity of the connecting tube 201a.

[0040] It should be further explained that the first hollow plug 201e can block the inner cavity of the connecting tube 201a in the initial state, and can release the blockage of the inner cavity of the connecting tube 201a when the first hollow plug 201e moves toward the direction close to the second spring 201d.

[0041] Among them, the sealing assembly 201 also includes a plug-in tube 201g arranged on the outside of the connecting tube 201a, a third spring 201h fixedly installed on the inner wall of the plug-in tube 201g, a second hollow plug 201i fixedly connected to the other end of the third spring 201h and used in conjunction with the first hollow plug 201e, a groove 201j opened on the outside of the plug-in tube 201g and used in conjunction with the ball 201f, and a sampling bag 201k connected to the inner cavity of the plug-in tube 201g and used in conjunction with the hose 102.

[0042] It should be explained that the plug tube 201g, the third spring 201h, the second hollow plug 201i and the sampling bag 201k are all relatively low-cost medical consumables, which are uniformly moved to a suitable area for centralized recycling and treatment after a single use.

[0043] When in use, slide sleeve 201b to a suitable position, release the limit on ball 201f, and apply pressure to first spring 201c. At this time, ball 201f can move freely, align plug 201g with connecting tube 201a, and insert slowly. During the insertion process, the front end of plug 201g will gradually contact the first hollow plug 201e and the second hollow plug 201i, which squeeze each other, respectively release the blockage of connecting tube 201a and plug 201g, so that hose 102 is connected with sampling bag 201k. With the further insertion of plug 201g, second spring 201d and third spring 201h are compressed to ensure that plug 201g can smoothly enter connecting tube 201a. When plug 201g is fully inserted, ball 201f is guided in the inner cavity of connecting tube 201a. Guided down, correctly embedded in the groove 201j outside the plug-in tube 201g, forming a mechanical limit, ensuring the tight connection between the plug-in tube 201g and the connecting tube 201a, releasing the pressure on the sliding sleeve 201b, and the sliding sleeve 201b automatically resets through the reaction force of the first spring 201c, and limits the ball 201f again. At this time, the ball 201f is not only limited by the sliding sleeve 201b, but also mechanically limits the plug-in tube 201g by embedding in the groove 201j, ensuring that the plug-in tube 201g will not fall off easily;

[0044] During sampling: the other end of the hose 102 is connected to the area to be sampled, and the driving assembly 203 and the guide assembly 204 are controlled to drive the turntable 103 and the squeezing roller 104 to rotate, so that the squeezing roller 104 periodically compresses the hose 102 to push the liquid medicine forward. The hose 102 quickly returns to its original shape after being squeezed, and a negative pressure area is formed in the tube, thereby achieving the effect of transporting the sample liquid medicine from the hose 102 to the sampling bag 201k;

[0045] After the sampling is completed: slide the sleeve 201b to a suitable position again, and slowly pull the plug tube 201g out of the connecting tube 201a. As the plug tube 201g is pulled out, the ball 201f gradually disengages from the groove 201j and returns to the free state of the inner cavity of the connecting tube 201a. After the plug tube 201g is completely pulled out, the sliding sleeve 201b is no longer subjected to external pressure, and the reaction force of the first spring 201c causes it to automatically reset and limit the ball 201f again. The ball 201f is limited by the sliding sleeve 201b and cannot move anymore, ensuring that the connecting tube 201g is completely pulled out. The inner cavity of the connecting tube 201a remains in a closed state, and the second spring 201d quickly returns to its original state after losing the squeezing of the plug-in tube 201g, pushing the first hollow plug 201e to move toward the inner cavity of the connecting tube 201a, and re-blocking the inner cavity of the connecting tube 201a. At the same time, the third spring 201h also returns to its original state, pushing the second hollow plug 201i to move toward the inner cavity of the plug-in tube 201g, and re-blocking the inner cavity of the plug-in tube 201g. The first hollow plug 201e and the second hollow plug 201i respectively block the inner cavities of the connecting tube 201a and the plug-in tube 201g to ensure that the drug solution does not leak.

[0046] In summary, the sealing component 201 can not only ensure that the interface between the hose 102 and the sampling bag 201k is tightly connected during the sampling process, but also automatically seal the interface between the hose 102 and the sampling bag 201k after the sampling is completed, so as to avoid leakage of the drug solution while ensuring the safety and reliability of the drug solution transmission.

[0047] Example 2

[0048] Reference Figure 1 , Figure 3 to Figure 7 , which is the second embodiment of the present invention. This embodiment is different from the first embodiment in that: this embodiment provides a driving component 203 for providing power to the turntable 103 and the squeezing roller 104, a guide component 204 for flexibly adjusting the rotation direction of the turntable 103 and the squeezing roller 104, and a positioning component 205 for preventing the rotation direction of the turntable 103 and the squeezing roller 104 from being offset.

[0049] Preferably, the driving assembly 203 includes a fixing plate 203a fixedly connected to the bottom of the mounting frame 202, a motor 203b adapted to be mounted on the top of the fixing plate 203a, a driving column 203c fixedly mounted on the output end of the motor 203b via a coupling, a first pulley 203d fixedly mounted on the outer surface of the driving column 203c, a belt 203e mounted on the outer surface of the first pulley 203d, a second pulley 203f mounted on the inner surface of the other end of the belt 203e, a driven column 203g fixedly connected to the outer end surface of the second pulley 203f, a driving gear 203h fixedly mounted on the through end of the driven column 203g, and a driven gear 203i meshed with the outer surface of the driving gear 203h.

[0050] Among them, the motor 203b directly drives the driving column 203c to rotate through the coupling, the first pulley 203d on the driving column 203c drives the second pulley 203f to rotate through the belt 203e, the second pulley 203f drives the driven column 203g and the driving gear 203h to rotate accordingly, and then drives the driven gear 203i to rotate in opposite directions through the driving gear 203h.

[0051] It should be noted that the driving gear 203h and the driven gear 203i are both located inside the mounting frame 202, and the outer end surfaces of the driving gear 203h and the driven gear 203i are fixedly mounted on the inner wall of the mounting frame 202 via bearings.

[0052] Furthermore, the guide assembly 204 includes a fixed sleeve 204a fixedly connected to the outer surface of the fixed plate 203a, a rotating shaft 204b in rotational contact with the inner wall of the fixed sleeve 204a, a swing block 204c fixedly sleeved on the outer surface of the rotating shaft 204b, a support shaft 204d in rotational contact with the inner surface of the swing block 204c, a guide gear 204e and a synchronous gear 204f respectively fixedly sleeved on the two side surfaces of the support shaft 204d, a transmission gear 204g meshing with the outer surface of the synchronous gear 204f, and a transmission shaft 204h fixedly connected to the inner surface of the transmission gear 204g and used in conjunction with the turntable 103.

[0053] It should be noted that when the rotating shaft 204b rotates, it can drive the swing block 204c, the support shaft 204d, the guide gear 204e and the synchronous gear 204f to move. When the swing block 204c drives the guide gear 204e to engage with the driving gear 203h, it can drive the support shaft 204d, the synchronous gear 204f, the transmission gear 204g, the transmission shaft 204h, the turntable 103 and the extrusion roller 104 to rotate. When the swing block 204c drives the guide gear 204e to engage with the driven gear 203i, it can drive the support shaft 204d, the synchronous gear 204f, the transmission gear 204g, the transmission shaft 204h, the turntable 103 and the extrusion roller 104 to rotate in the opposite direction.

[0054] Furthermore, the outer end surface of the rotating shaft 204b is fixedly mounted on the outer surface of the mounting frame 202 through a bearing, the through end of the transmission shaft 204h is fixedly connected to the outer surface of the turntable 103, and a bearing sleeve for matching rotation is installed at the connection between the transmission shaft 204h and the mounting box 101.

[0055] Furthermore, the positioning assembly 205 includes a knob 205a slidably mounted on the outer surface of the rotating shaft 204b, a fixed column 205b fixedly connected to the outer surface of the knob 205a, an M-shaped groove 205c opened on the outer surface of the fixed sleeve 204a and used in conjunction with the fixed column 205b, and a fourth spring 205d mounted on the outer surface of the rotating shaft 204b and used in conjunction with the knob 205a.

[0056] It should be further explained that the knob 205a can rotate or move linearly in the fixed sleeve 204a. When the knob 205a moves linearly, it can drive the fixed column 205b to move to the connecting area of ​​the M-shaped groove 205c to release the limitation of the M-shaped groove 205c on the fixed column 205b, so that the knob 205a can drive the fixed column 205b to rotate in the connecting area of ​​the M-shaped groove 205c. When the knob 205a rotates, it can also drive the rotating shaft 204b to rotate synchronously. When the knob 205a moves linearly, it can also apply pressure to the fourth spring 205d.

[0057] Specifically, the outer surface of the knob 205a is movably connected to the inner wall of the fixed sleeve 204a, and the fourth spring 205d is located inside the fixed sleeve 204a.

[0058] When in use, the motor 203b directly drives the driving column 203c and the first pulley 203d to rotate synchronously through the coupling, and the first pulley 203d drives the second pulley 203f and the driven column 203g to rotate accordingly through the belt 203e, and the driven column 203g drives the driving gear 203h and the driven gear 203i to rotate in opposite directions, thereby generating two opposite output powers;

[0059] When the rotation direction of the squeezing roller 104 needs to be controlled: linear movement releases the limit of the M-shaped groove 205c on the fixed column 205b, so that the knob 205a can drive the fixed column 205b to rotate in the connecting area of ​​the M-shaped groove 205c, and the knob 205a drives the rotating shaft 204b, the swing block 204c, the support shaft 204d, the guide gear 204e and the synchronous gear 204f to move, and the swing block 204c drives the guide gear 204e to engage with the driving gear 203h or the driven gear 203i, thereby driving the support shaft 204d, the synchronous gear 204f, the transmission gear 204g, the transmission shaft 204h, the turntable 103 and the squeezing roller 104 to rotate clockwise or counterclockwise, so as to achieve the effect of flexibly adjusting the rotation direction of the squeezing roller 104;

[0060] The fourth spring 205d provides a reset force to ensure that the knob 205a drives the fixed column 205b to automatically reset, and re-limits the knob 205a and the rotating shaft 204b to prevent the rotation direction of the rotating turntable 103 and the squeezing roller 104 from being offset.

[0061] In summary, through the direct cooperation of the components in the driving assembly 203, the guide assembly 204 and the positioning assembly 205, not only can the turntable 103 and the squeezing roller 104 be provided with rotational power, but the rotation direction of the turntable 103 and the squeezing roller 104 can also be flexibly adjusted, and the rotation direction of the turntable 103 and the squeezing roller 104 can be effectively prevented from being offset, so as to achieve the effect that the peristaltic pump body 100 can adapt to more complex sampling processes without the need for complex debugging.

[0062] Importantly, it should be noted that the construction and arrangement of the present application shown in a plurality of different exemplary embodiments are only exemplary. Although only a few embodiments are described in detail in this disclosure, it should be readily understood by those who refer to this disclosure that many modifications are possible (e.g., the size, scale, structure, shape and proportion of various elements, and parameter values ​​(e.g., temperature, pressure, etc.), installation arrangement, use of materials, color, directional changes, etc.) without substantially departing from the novel teachings and advantages of the subject matter described in the application. For example, the element shown as integrally formed can be composed of multiple parts or elements, the position of the element can be inverted or otherwise changed, and the nature or number or position of the discrete element can be changed or changed. Therefore, all such modifications are intended to be included in the scope of the present invention. The order or sequence of any process or method steps can be changed or reordered according to alternative embodiments. In the claims, any "device plus function" clause is intended to cover the structure of performing the function described herein, and is not only structurally equivalent but also equivalent structure. Without departing from the scope of the present invention, other replacements, modifications, changes and omissions can be made in the design, operating conditions and arrangement of the exemplary embodiments. Therefore, the invention is not limited to a specific embodiment, but extends to numerous modifications still falling within the scope of the appended claims.

[0063] Additionally, in order to provide a concise description of exemplary embodiments, all features of an actual embodiment (ie, those features that are not relevant to the best mode presently contemplated for carrying out the invention or those that are not relevant to implementing the invention) may not be described.

[0064] It should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention rather than to limit it. Although the present invention has been described in detail with reference to the preferred embodiments, those skilled in the art should understand that the technical solutions of the present invention may be modified or replaced by equivalents without departing from the spirit and scope of the technical solutions of the present invention, which should all be included in the scope of the claims of the present invention.

Claims

1. A sampling device for biomedicine, characterized in that: include, A peristaltic pump body (100) comprises a mounting box (101), a hose (102) fixedly connected to the inner surface of the mounting box (101), a rotating disk (103) arranged in the inner cavity of the mounting box (101), and squeezing rollers (104) fixedly mounted on the inner walls of both sides of the rotating disk (103) via bearings; The sampling mechanism (200) comprises a sealing component (201) used in conjunction with the hose (102) to prevent leakage of liquid medicine during the sampling process, a mounting frame (202) fixedly connected to the outer surface of the mounting box (101), a driving component (203) used in conjunction with driving the squeezing roller (104) to squeeze the hose (102), a guiding component (204) used in conjunction with changing the squeezing direction of the squeezing roller (104), and a positioning component (205) used in conjunction with fixing the conduction direction of the guiding component (204).

2. The biomedical sampling device according to claim 1, characterized in that: Both ends of the hose (102) extend to the outside of the installation box (101), and the outer surface of the squeezing roller (104) is in sliding contact with the outer surface of the hose (102).

3. The biomedical sampling device according to claim 2, characterized in that: The sealing assembly (201) comprises a connecting tube (201a) connected to the inner cavity of the hose (102), a sliding sleeve (201b) slidably sleeved on the outer surface of the connecting tube (201a), a first spring (201c) sleeved on the outer surface of the connecting tube (201a) and used in conjunction with the sliding sleeve (201b), a second spring (201d) fixedly mounted on the inner wall of the connecting tube (201a), a first hollow plug (201e) fixedly connected to the other end of the second spring (201d), and a plurality of balls (201f) distributed in a circular array in the inner cavity of the connecting tube (201a).

4. The biomedical sampling device according to claim 3, characterized in that: The sealing assembly (201) also includes a plug-in tube (201g) arranged on the outside of the connecting tube (201a), a third spring (201h) fixedly installed on the inner wall of the plug-in tube (201g), a second hollow plug (201i) fixedly connected to the other end of the third spring (201h) and used in conjunction with the first hollow plug (201e), a groove (201j) opened on the outside of the plug-in tube (201g) and used in conjunction with the ball (201f), and a sampling bag (201k) connected to the inner cavity of the plug-in tube (201g) and used in conjunction with the hose (102).

5. The biomedical sampling device according to claim 4, characterized in that: The driving assembly (203) comprises a fixing plate (203a) fixedly connected to the bottom of the mounting frame (202), a motor (203b) adapted to be mounted on the top of the fixing plate (203a), a driving column (203c) fixedly mounted on the output end of the motor (203b) via a coupling, a first pulley (203d) fixedly sleeved on the outer surface of the driving column (203c), a belt (203e) sleeved on the outer surface of the first pulley (203d), a second pulley (203f) sleeved on the inner surface of the other end of the belt (203e), a driven column (203g) fixedly connected to the outer end surface of the second pulley (203f), a driving gear (203h) fixedly mounted on the through end of the driven column (203g), and a driven gear (203i) meshed with the outer surface of the driving gear (203h).

6. The biomedical sampling device according to claim 5, characterized in that: The driving gear (203h) and the driven gear (203i) are both located on the inner side of the installation frame (202), and the outer end surfaces of the driving gear (203h) and the driven gear (203i) are fixedly mounted on the inner wall of the installation frame (202) via bearings.

7. The biomedical sampling device according to claim 6, characterized in that: The guide assembly (204) comprises a fixed sleeve (204a) fixedly connected to the outer surface of the fixed plate (203a), a rotating shaft (204b) in rotational contact with the inner wall of the fixed sleeve (204a), a swing block (204c) fixedly sleeved on the outer surface of the rotating shaft (204b), a support shaft (204d) in rotational contact with the inner surface of the swing block (204c), a guide gear (204e) and a synchronous gear (204f) respectively fixedly sleeved on both side surfaces of the support shaft (204d), a transmission gear (204g) meshed with the outer surface of the synchronous gear (204f), and a transmission shaft (204h) fixedly connected to the inner surface of the transmission gear (204g) and used in conjunction with the turntable (103).

8. The biomedical sampling device according to claim 7, characterized in that: The outer end surface of the rotating shaft (204b) is fixedly mounted on the outer surface of the installation frame (202) via a bearing, the through end of the transmission shaft (204h) is fixedly connected to the outer surface of the rotating disk (103), and a bearing sleeve for matching rotation is installed at the connection between the transmission shaft (204h) and the installation box (101).

9. The biomedical sampling device according to claim 8, characterized in that: The positioning assembly (205) includes a knob (205a) slidably mounted on the outer surface of the rotating shaft (204b), a fixing column (205b) fixedly connected to the outer surface of the knob (205a), an M-shaped groove (205c) opened on the outer surface of the fixing sleeve (204a) and used in conjunction with the fixing column (205b), and a fourth spring (205d) mounted on the outer surface of the rotating shaft (204b) and used in conjunction with the knob (205a).

10. The biomedical sampling device according to claim 9, characterized in that: The outer surface of the knob (205a) is movably connected to the inner wall of the fixed sleeve (204a), and the fourth spring (205d) is located inside the fixed sleeve (204a).