Three-chamber platelet-rich plasma preparation device

Abstract

The invention discloses a three-chamber platelet-rich plasma preparation device, and belongs to the technical field of medical instruments.The three-chamber platelet-rich plasma preparation device comprises a first main body, and the first main body is provided with a first chamber, a second chamber and a first connecting channel communicating the first chamber with the second chamber; a lower end cover capable of moving up and down is mounted at one end, close to the first cavity, of the first main body, a second main body capable of moving up and down is mounted at one end, close to the second cavity, of the first main body, and the second main body is provided with a third cavity and a second connecting channel communicating the second cavity with the third cavity; an upper end cover is installed at the end, close to the third cavity, of the second body. The platelet concentration can be efficiently improved, and the simplicity and convenience of operation and the economical efficiency of the preparation process are kept.

Description

Technical Field

[0001] The invention relates to a three-chamber platelet-rich plasma preparation device, belonging to the technical field of medical devices. Background Art

[0002] Platelet-rich plasma (PRP) is an autologous blood product rich in high-concentration platelets, obtained by centrifuging whole blood. PRP contains a variety of growth factors and cytokines, which are bioactive substances that can promote cell proliferation, differentiation and angiogenesis, thereby accelerating the process of tissue repair and regeneration. In the medical field, PRP is widely used to reduce inflammation and pain, improve skin conditions, promote hair regeneration, and increase pregnancy rates in reproductive medicine. Its anti-inflammatory and tissue healing and regeneration properties make PRP show significant effects and broad application prospects in the treatment of orthopedic injuries, plastic surgery recovery, skin beauty and various chronic diseases. Therefore, increasing the concentration of platelets in PRP is the key to achieving its therapeutic effect.

[0003] Traditional PRP preparation technology is complex to operate, costly, and difficult to flexibly adjust to accommodate individual differences. To address these challenges, there is an urgent need for a new PRP preparation device that simplifies the operating process, can efficiently increase platelet concentration, and maintains ease of operation and economy of the preparation process. Summary of the invention

[0004] The technical problem to be solved by the present invention is to overcome the deficiencies of the prior art and provide a three-chamber platelet-rich plasma preparation device that can efficiently increase the platelet concentration while maintaining the simplicity of operation and the economy of the preparation process.

[0005] The technical solution adopted by the present invention to solve the existing problems is: A three-chamber platelet-rich plasma preparation device includes a first main body, the first main body is provided with a first chamber, a second chamber and a first connecting channel connecting the first chamber with the second chamber, the first main body is provided with a lower end cover that can be moved up and down at one end close to the first chamber, and the lower end cover is provided with a lower sealing rod for controlling the opening or closing of the first connecting channel; the first main body is provided with a second main body that can be moved up and down at one end close to the second chamber, the second main body is provided with a third chamber and a second connecting channel connecting the second chamber with the third chamber; the second main body is provided with an upper end cover at one end located in the third chamber, and the upper end cover is provided with an upper sealing rod for controlling the opening or closing of the second connecting channel.

[0006] Preferably, the upper end cover is provided with a first insertion portion, the first insertion portion is a hollow structure, and a first light hole section and a first threaded hole section are provided in the first insertion portion; The upper sealing rod passes through the first insertion portion, and is provided with a first threaded shaft section and a first optical shaft section. One end of the upper sealing rod provided with the first optical shaft section extends into the third chamber, and one end of the upper sealing rod close to the first threaded section is located outside the upper end cover; The first threaded shaft section is threadedly connected with the first threaded hole section, and the outer circumferential surface of the first optical shaft section is in contact with the first optical hole section.

[0007] Preferably, a gas exhaust member and an inserting portion are provided on the top of the upper end cover, the gas exhaust member is used for exhausting gas, and the inserting portion is used for injecting liquid.

[0008] Preferably, the lower end cover is provided with a second insertion portion, the second insertion portion is a hollow structure, and a second light hole section and a second threaded hole section are provided in the second insertion portion; The lower sealing rod passes through the second insertion portion, and is provided with an isolating body, a second threaded shaft section and a second optical shaft section. One end of the lower sealing rod provided with the isolating body extends into the first chamber, and one end of the lower sealing rod close to the second optical shaft section is located outside the lower end cover; The second threaded shaft section is threadedly connected with the second threaded hole section, and the outer circumferential surface of the second optical shaft section is in contact with the second optical hole section.

[0009] Preferably, the first body is provided with an extraction portion located in the second chamber section for taking out liquid.

[0010] Preferably, the first body and the second body are marked with scale lines for injecting and extracting a required dose.

[0011] Compared with the prior art, the present invention has the following beneficial effects: The present invention innovatively adopts a technology that does not require manual extraction of excess plasma. It simplifies the operation process by optimizing the centrifugation process, reduces the required tools, avoids the inversion of the device during secondary centrifugation, reduces the size of the equipment and reduces costs. This innovative preparation device can efficiently increase platelet concentration while maintaining the simplicity of operation and the economy of the preparation process, which helps to meet the personalized treatment needs of different patients and promote the further development of PRP in clinical applications. BRIEF DESCRIPTION OF THE DRAWINGS

[0012] Figure 1 This is a structural diagram of a three-chamber platelet-rich plasma preparation device of the present invention; Figure 2 A full cross-sectional view of a three-chamber platelet-rich plasma preparation device of the present invention; Figure 3 This is a partial enlarged view of point A of the full cross-sectional view of a three-chamber platelet-rich plasma preparation device of the present invention; Figure 4 This is a partial enlarged view of point B of the full cross-sectional view of a three-chamber platelet-rich plasma preparation device of the present invention.

[0013] In the figure: 1. first body, 101. first chamber, 102. first connecting channel, 103. second chamber, 104. extraction part, 105. first sealing body, 2. second body, 201. second connecting channel, 202. third chamber, 203. second sealing body, 3. upper end cover, 301. exhaust member, 302. insertion part, 303. first insertion part, 3031. first light hole section, 3032. first threaded hole section, 30 4. Third sealing body, 4. Upper sealing rod, 401. First threaded shaft section, 402. First optical axis section, 403. Fourth sealing body, 404. Fifth sealing body, 5. Lower end cover, 501. Second extension portion, 502. Second optical hole section, 503. Second threaded hole section, 6. Lower sealing rod, 601. Isolation body, 602. Sixth sealing body, 603. Second threaded shaft section, 604. Second optical axis section, 605. Seventh sealing body. DETAILED DESCRIPTION

[0014] This specification and claims do not use differences in names as a way to distinguish components, but use differences in the functions of components as the criteria for distinction. In the description of the present invention, it should be understood that the terms "upper", "lower", "front", "back", "left", "right", "horizontal", etc. indicate positions or positional relationships based on the positions or positional relationships shown in the accompanying drawings, which are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on the present invention. In the present invention, unless otherwise clearly specified and limited, the terms "install", "connect", "connect", "fix", etc. should be understood in a broad sense, and for ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to the specific circumstances.

[0015] like Figure 1-Figure 4 A three-chamber platelet-rich plasma preparation device is shown, comprising a first main body 1, the first main body 1 is provided with a first chamber 101, a second chamber 103 and a first connecting channel 102 connecting the first chamber 101 and the second chamber 103, and a lower end cover 5 that can move up and down is installed at one end of the first main body 1 close to the first chamber 101, the first main body 1 is threadedly connected to the lower end cover 5, and the lower end cover 5 is threadedly connected to the first main body 1 to move up and down.

[0016] The first body 1 is provided with a second body 2 that can move up and down at one end close to the second chamber 103. The first body 1 is threadedly connected to the second body 2. The second body 2 is threadedly connected to the first body 1 to move up and down. The second body 2 is provided with a third chamber 202 and a second connecting channel 201 that connects the second chamber 103 and the third chamber 202. An upper end cover 3 is provided at one end of the second body 2 located at the third chamber 202. The upper end cover 3 is provided with a first insertion portion 303 . The first insertion portion 303 is a hollow structure. A first light hole section 3031 and a first threaded hole section 3032 are provided in the first insertion portion 303 .

[0017] The upper end cover 3 is provided with an upper sealing rod 4 for controlling the opening or closing of the second connecting channel 201. The upper sealing rod 4 passes through the first extension portion 303. The upper sealing rod 4 is provided with a first threaded shaft section 401 and a first optical axis section 402. One end of the upper sealing rod 4 provided with the first optical axis section 402 extends into the third chamber 202, and the end of the upper sealing rod 4 close to the first threaded shaft section 401 is located outside the upper end cover 3.

[0018] The first threaded shaft section 401 is threadedly connected with the first threaded hole section 3032, and the outer circumferential surface of the first optical shaft section 402 abuts against the first optical hole section 3031. The upper sealing rod 4 can be rotated to move up and down on the first extending portion 303.

[0019] The top of the upper end cover 3 is provided with an exhaust member 301 and an insertion portion 302. The exhaust member 301 is used to exhaust the air in the device when liquid is injected into the device through the insertion portion 302, and the insertion portion 302 is used for injecting liquid.

[0020] The lower end cover 5 is provided with a second insertion portion 501 . The second insertion portion 501 is a hollow structure. A second light hole section 502 and a second threaded hole section 503 are provided in the second insertion portion 501 .

[0021] The lower end cover 5 is provided with a lower sealing rod 6 for controlling the opening or closing of the first connecting channel 102. The lower sealing rod 6 passes through the second extension portion 501. The lower sealing rod 6 is provided with an isolation body 601, a second threaded shaft segment 603 and a second optical axis segment 604. One end of the lower sealing rod 6 provided with the isolation body 601 extends into the first chamber 101, and the end of the lower sealing rod 6 close to the second optical axis segment 604 is located outside the lower end cover 5.

[0022] The second threaded shaft section 603 is threadedly connected with the second threaded hole section 503, and the outer circumferential surface of the second optical shaft section 604 abuts against the second optical hole section 502. The lower sealing rod 6 is rotated to move up and down on the second extending portion 501.

[0023] The first body 1 is provided with an extraction portion 104 located in the second chamber 103 for taking out liquid.

[0024] The first body 1 and the second body 2 are marked with scale lines to facilitate accurate injection and extraction of required doses.

[0025] In order to further enhance the sealing performance of the three-chamber platelet-rich plasma preparation device, prevent liquid leakage, and avoid cross infection, the three-chamber platelet-rich plasma preparation device is provided with a sealing system, which includes a first sealing body 105, a second sealing body 203, a third sealing body 304, a fourth sealing body 403, a fifth sealing body 404, a sixth sealing body 602, and a seventh sealing body 605. The first sealing body 105 is arranged at the connection between the lower end cover 5 and the first main body 1, and is used for sealing between the lower end cover 5 and the first main body 1. The second sealing body 203 is arranged at the connection between the first main body 1 and the second main body 2, and is used for sealing between the first main body 1 and the second main body 2. The third sealing body 304 is arranged at the connection between the upper end cover 3 and the second main body 2, and is used for sealing between the upper end cover 3 and the second main body 2. The fourth sealing body 403 is arranged at the connection between the first optical axis section 402 and the first optical hole section 3031, and is used for sealing between the upper sealing rod 4 and the upper end cover 3. The fifth sealing body 404 is arranged on the first optical axis section 402 of the upper sealing rod 4 close to the second connecting channel 201, and is used for sealing between the upper sealing rod 4 and the second connecting channel 201 when the upper sealing rod 4 is connected to the second connecting channel 201. The sixth sealing body 602 is arranged on the isolation body 601, and is used for sealing between the isolation body 601 and the first connecting channel 102 when the isolation body 601 is connected to the first connecting channel 102. The seventh sealing body 605 is arranged at the connection between the second optical axis section 604 and the second optical hole section 502, and is used for sealing between the lower end cover 5 and the lower sealing rod 6.

[0026] The preparation method of the three-chamber platelet-rich plasma preparation device is as follows: 1. Blood injection: First, the collected blood is injected into the device through the insertion portion 302 on the upper end cover 3. At this time, the blood will fill the first chamber 101, the first connecting channel 102, the second chamber 103, the second connecting channel 201 and the lower part of the third chamber 202 of the entire device; 2. Initial centrifugation: Place the device in a centrifuge for the first centrifugation. After centrifugation, the blood will be separated into three layers: the red blood cell layer at the bottom, the plasma layer at the top, and the white membrane layer rich in white blood cells and platelets in the middle; 3. Red blood cell separation: Rotate and adjust the position of the lower end cap 5 so that it moves axially close to the first connecting channel 102. As the volume of the first chamber 101 decreases, the blood will gradually flow to the second chamber 103 and the third chamber 202. When the buffy coat layer completely enters the first connecting channel 102, stop adjusting the position of the lower end cap 5. 4. Sealing the red blood cell layer: Rotate the lower sealing rod 6 until the isolating body 601 completely enters the first connecting channel 102 and forms a closed space, ensuring that the red blood cell layer is isolated in the first chamber 101, while the buffy coat layer and the plasma layer are located in the second chamber 103 and the third chamber 202, respectively; 5. Second centrifugation: The buffy coat layer has entered the second chamber 103 and can be centrifuged for the second time without inversion. In order to further concentrate the platelets in the buffy coat layer, the device is placed in the centrifuge again for the second centrifugation operation; 6. Concentration adjustment: according to the required platelet concentration, the upper end cover 3 is rotated to move downward in the axial direction, thereby squeezing the upper plasma into the third chamber 202. When the plasma layer in the second chamber 103 reaches the required liquid level, the upper end cover 3 is stopped from rotating, and the upper sealing rod 4 is rotated until the upper sealing rod 4 completely seals the second connecting channel 201. 7. Extracting PRP: Finally, the evenly mixed buffy coat layer and the remaining plasma are collected through the extraction portion 104 at the second chamber 103, so as to obtain platelet-rich plasma of the desired concentration.

[0027] The design of the second body 2 and the third chamber 202 of the device does not require manual extraction of excess plasma without inverting it. The required platelet-rich plasma can be extracted according to the required amount by adjusting the second body 2. This device optimizes the centrifugation process, simplifies the operation process, reduces the required tools, and avoids inverting the device during secondary centrifugation, reducing the size of the device and reducing costs. It can effectively increase the platelet concentration and help meet the personalized treatment needs of different patients.

[0028] The embodiments of the present invention are described in detail above in conjunction with the accompanying drawings, but the present invention is not limited to the above embodiments, and various changes can be made within the knowledge scope of ordinary technicians in the relevant technical field without departing from the purpose of the present invention.

Claims

1. A three-chamber platelet-rich plasma preparation device, comprising a first body (1), the first body (1) being provided with a first chamber (101), a second chamber (103) and a first connecting channel (102) connecting the first chamber (101) and the second chamber (103), characterized in that: A lower end cover (5) that can move up and down is installed at one end of the first body (1) close to the first chamber (101), and the lower end cover (5) is provided with a lower sealing rod (6) for controlling the opening or closing of the first connecting channel (102); A second body (2) that can move up and down is mounted on one end of the first body (1) close to the second chamber (103); the second body (2) is provided with a third chamber (202) and a second connecting channel (201) connecting the second chamber (103) and the third chamber (202); An upper end cover (3) is installed at one end of the second body (2) located in the third chamber (202), and the upper end cover (3) is provided with an upper sealing rod (4) for controlling the opening or closing of the second connecting channel (201).

2. The three-chamber platelet-rich plasma preparation device according to claim 1, characterized in that: The upper end cover (3) is provided with a first insertion portion (303), the first insertion portion (303) is a hollow structure, and a first light hole section (3031) and a first threaded hole section (3032) are provided in the first insertion portion (303); The upper sealing rod (4) passes through the first insertion portion (303), the upper sealing rod (4) is provided with a first threaded shaft section (401) and a first optical shaft section (402), one end of the upper sealing rod (4) provided with the first optical shaft section (402) extends into the third chamber (202), and one end of the upper sealing rod (4) close to the first threaded shaft section (401) is located outside the upper end cover (3); The first threaded shaft section (401) is threadedly connected to the first threaded hole section (3032), and the outer cylindrical surface of the first optical shaft section (402) is in abutment with the first optical hole section (3031).

3. The three-chamber platelet-rich plasma preparation device according to claim 2, characterized in that: The top of the upper end cover (3) is provided with an exhaust member (301) and an inserting portion (302); the exhaust member (301) is used for exhausting gas, and the inserting portion (302) is used for injecting liquid.

4. The three-chamber platelet-rich plasma preparation device according to claim 1, characterized in that: The lower end cover (5) is provided with a second insertion portion (501), the second insertion portion (501) is a hollow structure, and a second light hole section (502) and a second threaded hole section (503) are provided in the second insertion portion (501); The lower sealing rod (6) passes through the second insertion portion (501), and the lower sealing rod (6) is provided with an isolating body (601), a second threaded shaft section (603), and a second optical axis section (604); one end of the lower sealing rod (6) provided with the isolating body (601) extends into the first chamber (101), and one end of the lower sealing rod (6) close to the second optical axis section (604) is located outside the lower end cover (5); The second threaded shaft section (603) is threadedly connected to the second threaded hole section (503), and the outer circumferential surface of the second optical shaft section (604) is in abutment with the second optical hole section (502).

5. The three-chamber platelet-rich plasma preparation device according to claim 1, characterized in that: The first body (1) is provided with an extraction portion (104) located in the second chamber (103) for taking out liquid.

6. The three-chamber platelet-rich plasma preparation device according to claim 1, characterized in that: The first body (1) and the second body (2) are marked with scale lines for injecting and extracting a required dose.

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