Novel nucleic acid extractor

By designing a new type of nucleic acid extractor, using electric push rod and electric slide rail technology, the movement of the magnetic rod body and the magnetic rod sleeve is realized, and the nucleic acid is moved to different solutions of the reagent strip, which solves the problem of waste of consumables in the existing technology, and improves the applicability and extraction efficiency.

CN120059938AInactive Publication Date: 2025-05-30JINAN YOUKE BIOTECHNOLOGY CO LTD
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Patent Information

Application Number
CN202510306744.4
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-03-15
Publication Date
2025-05-30
Estimated Expiration
Not applicable · inactive patent

AI Technical Summary

Technical Problem

The existing nucleic acid extractor has a small sample size, and the use of 96 deep-well plates as consumables has resulted in wasting consumables, which is poor in applicability and is difficult to meet the testing needs of scientific research or small sample size.

Method used

A new type of nucleic acid extractor is designed, using technologies such as electric push rods and electric slides to realize the movement of the magnetic rod body and magnetic rod sleeve, which can move the nucleic acid into different solutions of the reagent strips, and combine with the extraction components inside the protective case to realize nucleic acid extraction. In this device, each reagent strip is arranged longitudinally and the magnetic rod body is arranged horizontally. Each reagent strip can be detected separately and adapted to the extraction of different numbers of nucleic acid samples.

Benefits of technology

Through this device, the waste of deep-well plates can be effectively avoided, and the applicability can be improved. It is suitable for the extraction of different numbers of nucleic acid samples, achieving an efficient nucleic acid extraction process.

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Abstract

The invention discloses a novel nucleic acid extractor which comprises a protective shell, a groove is formed in the front side of the protective shell, an electric sliding rail is fixedly connected to the top of the groove, an electric push rod is slidably connected to the bottom of the electric sliding rail through a sliding block, and a connecting box is fixedly connected to the bottom end of the electric push rod. The vertical center line of the connecting box coincides with the central axis of the electric push rod, the bottom of the connecting box is fixedly connected with a plurality of magnetic rod bodies, the outer sides of the plurality of magnetic rod bodies are fixedly connected with detection rings, and the bottom of the groove is provided with a movable carrying box. According to the invention, each reagent strip is longitudinally arranged in the carrying box, and the magnetic bar bodies are transversely arranged, so that each reagent strip can be independently detected by each independent magnetic bar body and magnetic bar sleeve, when different quantities of nucleic acid samples are extracted, only a corresponding quantity of reagent strips need to be placed, and waste of deep-hole plates is not caused; therefore, the applicability of the device is improved.
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Description

Technical Field

[0001] The present invention belongs to the technical field of nucleic acid extractors, and specifically relates to a novel nucleic acid extractor. Background Art

[0002] A nucleic acid extractor is an instrument used to automatically extract nucleic acids (DNA or RNA) from biological samples. It utilizes specific groups on the surface of magnetic beads to specifically adsorb nucleic acids. Under the action of a lysis solution, cells rupture to release nucleic acids. Through steps such as washing and separation, the magnetic beads are separated from other impurities by a magnetic field, and finally pure nucleic acids are eluted. It can realize functions such as sample loading, lysis, and mixing of samples. Some are equipped with robotic arms and pipetting needles, which can accurately aspirate and dispense samples and reagents. It is mainly used for detecting pathogen nucleic acids, such as the nucleic acid detection of the novel coronavirus; it can also be used for tumor gene detection to assist in the early diagnosis of cancer, etc. In experiments such as gene cloning, gene expression analysis, and research on the structure and function of genetic materials, it is an important tool for extracting high-quality nucleic acids.

[0003] In the prior art, the patent of Chinese Patent CN222139067U discloses a nucleic acid extractor, including an instrument box body. A sample dispensing box is placed inside the instrument box body. There is a magnetic rod module above the sample dispensing box. There is an XY-axis movement module at the bottom inside the instrument box body. The XY-axis movement module carries the sample dispensing box. There is a Z-axis movement module and a Z-axis movement motor on the back of the instrument box body. The slider of the Z-axis movement module is connected to a magnetic rod module frame, and the magnetic rod module frame carries the magnetic rod module. This utility model can simultaneously perform nucleic acid extraction on a relatively large number of samples. When performing nucleic acid extraction on a relatively large number of samples, the translation and lifting structures of the samples and the magnetic rods are simple, the control program is concise, and when the magnetic rod descends, it enters into the magnetic rod sleeve, avoiding direct contact between the magnetic rod and the sample liquid, and it is more convenient and simple to disassemble the magnetic rod and the magnetic rod sleeve.

[0004] However, when the nucleic acid extractor provided in the above technical solution is actually used, there are still many drawbacks. For example, in existing nucleic acid extractors, due to the huge sample volume, 96-well deep plates are mostly used as consumables, which will cause waste of consumables when used in scientific research and for cases with a small sample volume, making it not suitable for scientific research or the inspection requirements with a small sample volume, resulting in poor applicability. Summary of the Invention

[0005] The purpose of this part is to outline some aspects of the embodiments of the present invention and briefly introduce some preferred embodiments. Some simplifications or omissions may be made in this part, as well as in the abstract and title of the present application, to avoid obscuring the purpose of this part, the abstract, and the title. However, such simplifications or omissions cannot be used to limit the scope of the present invention.

[0006] To solve the problem of the existing nucleic acid extractor in the above-mentioned background technology, due to the huge sample volume, 96-well deep plates are mostly used as consumables, which will cause waste of consumables when used for scientific research and in the case of a small sample volume, making it unsuitable for the inspection needs of scientific research or small sample volumes, resulting in poor applicability. The present invention adopts the following technical solutions.

[0007] A new type of nucleic acid extractor includes a protective shell. A groove is provided on the front side of the protective shell. An electric slide rail is fixedly connected to the top of the groove. The bottom of the electric slide rail is slidably connected with an electric push rod through a slider. The bottom end of the electric push rod is fixedly connected with a connection box. The vertical center line of the connection box coincides with the central axis of the electric push rod. A plurality of magnetic rod bodies are fixedly connected to the bottom of the connection box. Detection rings are fixedly connected to the outer sides of the plurality of magnetic rod bodies. The central axis of the magnetic rod body coincides with the central axis of the detection ring. A movable carrier box is provided at the bottom of the groove. A plurality of reagent strips are arranged inside the carrier box. One end of the reagent strip is inserted with a magnetic rod sleeve. An induction coil is provided at the top edge of the magnetic rod sleeve. The central axis of the induction coil coincides with the central axis of the magnetic rod sleeve.

[0008] Preferably, an extraction component is provided inside the protective shell. A control panel is provided on the top of the protective shell. A plurality of feet are fixedly connected to the bottom of the protective shell. The plurality of feet are symmetric about the vertical center line of the protective shell.

[0009] Preferably, the plurality of reagent strips are evenly distributed about the horizontal center line of the carrier box. The magnetic rod bodies are evenly distributed about the horizontal center line of the connection box. The distance between adjacent two magnetic rod bodies is equal to the distance between adjacent two magnetic rod sleeves.

[0010] Preferably, a plurality of round grooves for loading solutions are provided on the reagent strip. The plurality of round grooves are evenly distributed about the long side of the reagent strip. The outer size of the magnetic rod sleeve is in conformity with the inner size of the induction coil.

[0011] Preferably, a round hole plate is provided on the top of the carrier box. The round hole plate is inserted with the reagent strip. The inner diameter of the round hole of the round hole plate is in conformity with the outer diameter of the round groove of the reagent strip. The bottom surface of the round hole plate is in contact with the top surface of the carrier box. The outer size of the round hole plate is in conformity with the outer size of the carrier box. A handle is fixedly connected to one side of the round hole plate.

[0012] Preferably, a plurality of cylinders are provided at the rear end of the carrier box. The ends of the cylinders are fixedly connected to the protective shell. The plurality of cylinders are symmetric about the vertical center line of the carrier box. A plurality of guide rails are provided at the bottom of the groove. The guide rails are slidably connected with the carrier box through sliders. The guide rails are symmetric about the vertical center line of the carrier box. The two sides of the carrier box are in contact with the inner walls of the groove.

[0013] Preferably, a heater is provided at the front end of the cartridge, the heater communicates with the inside of the cartridge, and the horizontal center line of the heater coincides with the horizontal center of the cartridge.

[0014] Preferably, a flip cover is provided at the bottom of the front end of the protective shell. One side of the flip cover is rotatably connected to the protective shell through a hinge. A sealing ring is fixedly connected to one side of the flip cover, and the outer size of the sealing ring matches the inner size of the groove.

[0015] Preferably, a plurality of heat dissipation holes are provided on both sides of the protective shell. The plurality of heat dissipation holes are arranged in a rectangular array on the side surface of the protective shell. A heat dissipation fan is fixedly connected to the rear side of the protective shell, and the back of the heat dissipation fan is a mesh structure.

[0016] Preferably, a connecting wire is fixedly connected to the rear side of the protective shell. A horn tube is provided at the connection between the protective shell and the connecting wire, and the horn tube is fixedly connected to the protective shell.

[0017] Beneficial Effects

[0018] Compared with the prior art, the beneficial effects of the present invention are as follows:

[0019] 1. In the present invention, the electric push rod can be used to lower the connection box, facilitating the insertion of multiple magnetic rod bodies into the magnetic rod sleeves of different reagent strips. In combination with the use of the electric slide rail and the slider, the magnetic rod body and the magnetic rod sleeve can be moved, so that the nucleic acid can be moved into different solutions of the reagent strip. At the same time, in combination with the extraction component inside the protective shell, the purpose of nucleic acid extraction can be achieved. In this device, each reagent strip is longitudinally arranged in the cartridge, and the magnetic rod bodies are horizontally arranged, so that each individual magnetic rod body and magnetic rod sleeve can be used to individually detect each reagent strip. When extracting different numbers of nucleic acid samples, only the corresponding number of reagent strips need to be placed, without causing waste of deep-hole plates, thereby improving the applicability of this device.

[0020] 2. In the present invention, the flip cover can be rotated through the hinge, facilitating the opening of the groove of the protective shell. Closing the flip cover can protect the devices inside the groove. The setting of the sealing ring can enhance the tightness when the flip cover is closed. Through the control panel, this device can be operated. The setting of the reagent strip is convenient for loading nucleic acid samples and magnetic beads. The round hole plate can be used to place multiple individual reagent strips, facilitating the user to select the appropriate number of samples for nucleic acid extraction according to actual needs.

[0021] 3. The present invention utilizes a connecting wire to connect this device to an external power supply device, facilitating the provision of power to this device. The setting of the horn tube plays a protective role in the connection between the connecting wire and the protective shell, preventing wear of the connecting wire. Through the combined use of heat dissipation holes and a heat dissipation fan, when this device is in use, it can dissipate heat from the circuit components inside the protective shell, preventing the device from getting hot during long-term use. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] Figure 1 is a schematic perspective view of the overall structure of the present invention;

[0023] Figure 2 is a schematic perspective view of the back structure of the present invention;

[0024] Figure 3 is a schematic perspective view of a partial structure of the present invention;

[0025] Figure 4 is a schematic perspective view of the carrier box of the present invention;

[0026] Figure 5 is a schematic perspective view of the reagent strip of the present invention;

[0027] Figure 6 is a schematic perspective view of the bottom structure of the present invention;

[0028] Figure 7 is a schematic perspective view of the magnetic rod body of the present invention;

[0029] Figure 8 of the present invention Figure 4 is an enlarged schematic view of part A in the figure.

[0030] The corresponding relationship between the reference numerals and the component names in the figures is as follows:

[0031] 1, protective shell; 2, groove; 3, electric push rod; 4, detection ring; 5, magnetic rod body; 6, carrier box; 7, reagent strip; 8, magnetic rod sleeve; 9, induction coil; 10, control panel; 11, foot pad; 12, round hole plate; 13, connection box; 14, handle; 15, guide rail; 16, heater; 17, flip cover; 18, sealing ring; 19, heat dissipation hole; 20, heat dissipation fan; 21, connecting wire; 22, horn tube; 23, cylinder; 24, electric slide rail. DETAILED DESCRIPTION OF THE EMBODIMENTS

[0032] In order to make the above objects, features, and advantages of the present invention more obvious and understandable, the following detailed description of the specific embodiments of the present invention is provided in conjunction with the accompanying drawings of the specification.

[0033] In the following description, numerous specific details are set forth in order to provide a thorough understanding of the present invention. However, the present invention may be practiced in other ways different from those described herein. Persons skilled in the art can make similar extensions without departing from the spirit of the present invention. Therefore, the present invention is not limited by the specific embodiments disclosed below.

[0034] Secondly, the so-called "one embodiment" or "embodiment" herein refers to a specific feature, structure, or characteristic that may be included in at least one implementation manner of the present invention. The phrase "in one embodiment" that appears in different places in this specification does not necessarily refer to the same embodiment, nor is it an individual or alternative embodiment that is mutually exclusive with other embodiments. The present invention provides the following embodiments.

[0035] Please refer to Figures 1-8 , an embodiment provided by the present invention: a novel nucleic acid extractor, including a protective shell 1. A groove 2 is provided on the front side of the protective shell 1. In this embodiment, an extraction component is provided inside the protective shell 1. A control panel 10 is provided on the top of the protective shell 1. A plurality of feet 11 are fixedly connected to the bottom of the protective shell 1. The plurality of feet 11 are symmetric about the vertical center line of the protective shell 1. By means of the feet 11, the device can be placed on an external horizontal plane and propped up, preventing wear between the bottom of the protective shell 1 and the external horizontal plane.

[0036] In this embodiment, a connecting line 21 is fixedly connected to the rear side of the protective shell 1. A horn tube 22 is provided at the connection between the protective shell 1 and the connecting line 21. The horn tube 22 is fixedly connected to the protective shell 1. By means of the connecting line 21, the device can be connected to an external power supply device, facilitating the supply of power to the device. The setting of the horn tube 22 protects the connection between the connecting line 21 and the protective shell 1, preventing wear of the connecting line 21.

[0037] In this embodiment, a plurality of heat dissipation holes 19 are provided on both sides of the protective shell 1. The plurality of heat dissipation holes 19 are distributed in a rectangular array on the side surface of the protective shell 1. A heat dissipation fan 20 is fixedly connected to the rear side of the protective shell 1. The back surface of the heat dissipation fan 20 is of a mesh structure. By the combined use of the heat dissipation holes 19 and the heat dissipation fan 20, when the device is in use, the circuit components inside the protective shell 1 can be dissipated heat, preventing the device from getting hot during long-term use.

[0038] In this embodiment, a flip cover 17 is provided at the bottom of the front end of the protective shell 1. One side of the flip cover 17 is rotatably connected to the protective shell 1 through a hinge. A sealing ring 18 is fixedly connected to one side of the flip cover 17. The outer dimension of the sealing ring 18 matches the inner dimension of the groove 2. The flip cover 17 can be rotated through the hinge, facilitating the opening of the groove 2 of the protective shell 1. Closing the flip cover 17 can protect the components inside the groove 2. The setting of the sealing ring 18 can enhance the tightness when the flip cover 17 is closed.

[0039] In this embodiment, the top of the groove 2 is fixedly connected to an electric slide rail 24, the bottom of the electric slide rail 24 is slidably connected to an electric push rod 3 through a slider, the bottom end of the electric push rod 3 is fixedly connected to a connecting box 13, the vertical center line of the connecting box 13 coincides with the central axis of the electric push rod 3, the bottom of the connecting box 13 is fixedly connected to a plurality of magnetic rod bodies 5, the outer sides of the plurality of magnetic rod bodies 5 are fixedly connected to a detection ring 4, the central axis of the magnetic rod body 5 coincides with the central axis of the detection ring 4, a movable carrier box 6 is provided at the bottom of the groove 2, a plurality of reagent strips 7 are provided inside the carrier box 6, a circular hole plate 12 is provided at the top of the carrier box 6, the circular hole plate 12 and the reagent strip 7 are plugged in, and the inner diameter of the circular hole of the circular hole plate 12 coincides with the outer diameter of the circular groove of the reagent strip 7 The bottom surface of the circular hole plate 12 fits with the top surface of the carrier box 6, and the outer size of the circular hole plate 12 matches the outer size of the carrier box 6. A handle 14 is fixedly connected to one side of the circular hole plate 12. A plurality of circular grooves for loading solutions are provided on the reagent strip 7. The plurality of circular grooves are evenly distributed about the long side of the reagent strip 7. The device can be operated through the control panel 10. The plurality of circular grooves provided on the reagent strip 7 can load a variety of different solutions, which is convenient for mixing different solutions. The circular hole plate 12 can be used to place a plurality of separate reagent strips 7, which is convenient for users to select a suitable number of samples for nucleic acid extraction according to actual needs. The circular hole plate 12 can be lifted by the handle 14, which is convenient for loading a plurality of reagent strips 7 into the carrier box 6.

[0040] In this embodiment, a plurality of cylinders 23 are provided at the rear end of the carrier box 6, and the ends of the cylinders 23 are fixedly connected to the protective shell 1. The plurality of cylinders 23 are symmetrical about the vertical center line of the carrier box 6. A plurality of guide rails 15 are provided at the bottom of the groove 2. The guide rails 15 are slidably connected to the carrier box 6 through sliders. The guide rails 15 are symmetrical about the vertical center line of the carrier box 6. Both sides of the carrier box 6 are in contact with the inner wall of the groove 2. The cylinders 23 can be used to move the carrier box 6 to the bottom of the magnetic rod body 5. The setting of the guide rails 15 and the slider can ensure the stability of the movement and prevent large shaking during movement.

[0041] One end of the reagent strip 7 is plugged with a magnetic rod sleeve 8. An induction coil 9 is arranged at the top edge of the magnetic rod sleeve 8. The central axis of the induction coil 9 coincides with the central axis of the magnetic rod sleeve 8. The outer dimension of the magnetic rod sleeve 8 matches the inner dimension of the induction coil 9. Multiple reagent strips 7 are evenly distributed about the horizontal center line of the carrier box 6. The magnetic rod bodies 5 are evenly distributed about the horizontal center line of the connection box 13. The distance between two adjacent magnetic rod bodies 5 is equal to the distance between two adjacent magnetic rod sleeves 8. By using the cooperation of the detection ring 4 and the induction coil 9, it is possible to detect whether there is a magnetic rod sleeve 8 below the magnetic rod body 5. When the magnetic rod sleeve 8 is detected, the connection box 13 can be lowered by the electric push rod 3, facilitating the lowering of multiple magnetic rod bodies 5 and inserting them into the magnetic rod sleeves 8 of different reagent strips 7. By using the cooperation of the electric slide rail 24 and the slider, the magnetic rod body 5 and the magnetic rod sleeve 8 can be moved, so that the nucleic acid can be moved into different solutions of the reagent strip 7. At the same time, in cooperation with the extraction component inside the protective shell 1, the purpose of nucleic acid extraction can be achieved. In this device, each reagent strip 7 is longitudinally arranged in the carrier box 6, and the magnetic rod bodies 5 are transversely arranged, so that each individual magnetic rod body 5 and magnetic rod sleeve 8 can separately detect each reagent strip 7. When extracting different numbers of nucleic acid samples, only the corresponding number of reagent strips 7 need to be placed, without causing waste of the deep-hole plate, thereby improving the applicability of this device.

[0042] In this embodiment, a heater 16 is arranged at the front end of the carrier box 6. The heater 16 communicates with the inside of the carrier box 6. The horizontal center line of the heater 16 coincides with the horizontal center of the carrier box 6. By means of the heater 16, the sample in the reagent strip 7 can be heated during extraction.

[0043] Working principle: When using this device, first, the device can be placed on an external horizontal surface and propped up by the foot pads 11 to prevent wear between the bottom of the protective shell 1 and the external horizontal surface. The connection line 21 can be used to connect this device with an external power supply device to facilitate power supply for this device. The setting of the horn tube 22 plays a protective role in the connection between the connection line 21 and the protective shell 1, preventing wear of the connection line 21. By using the cooperation of the heat dissipation holes 19 and the heat dissipation fan 20, when this device is in use, the circuit components inside the protective shell 1 can be dissipated heat to prevent the device from getting hot during long-term use.

[0044] The flip cover 17 can be rotated by the hinge to open the groove 2 of the protective shell 1. Closing the flip cover 17 can protect the device inside the groove 2. The setting of the sealing ring 18 can enhance the tightness of the flip cover 17 when it is closed. The device can be operated through the control panel 10. The multiple circular grooves set on the reagent strip 7 can load a variety of different solutions, which is convenient for mixing different solutions. The circular hole plate 12 can be used to place multiple separate reagent strips 7, which is convenient for users to select a suitable number of samples for nucleic acid extraction according to actual needs. The circular hole plate 12 can be lifted by the handle 14 to facilitate loading multiple reagent strips 7 into the carrier box 6. The cylinder 23 can be used to move the carrier box 6 to the bottom of the magnetic rod body 5. The setting of the guide rail 15 and the slider can ensure the stability of the movement and prevent large shaking during movement. The magnetic rod can be adjusted by the use of the detection ring 4 and the induction coil 9. Whether there is a magnetic rod sleeve 8 under the body 5 is detected. When the magnetic rod sleeve 8 is detected, the connecting box 13 can be moved downward by the electric push rod 3, so that multiple magnetic rod bodies 5 can be lowered and inserted into the magnetic rod sleeves 8 of different reagent strips 7. The use of the electric slide rail 24 and the slider can make the magnetic rod body 5 and the magnetic rod sleeve 8 move, so that the nucleic acid can be moved to different solutions of the reagent strip 7. At the same time, with the extraction component inside the protective shell 1, the purpose of nucleic acid extraction can be achieved. In this device, each reagent strip 7 is arranged longitudinally in the carrier box 6, and the magnetic rod body 5 is arranged transversely, so that each individual magnetic rod body 5 and the magnetic rod sleeve 8 can perform separate detection on each reagent strip 7. When extracting different numbers of nucleic acid samples, only the corresponding number of reagent strips 7 need to be placed, and no waste of deep-well plates will be caused, thereby improving the applicability of the device. The heater 16 can heat the sample in the reagent strip 7 during extraction.

[0045] The above content is a further detailed description of the present invention in combination with specific implementation methods. It cannot be determined that the specific implementation of the present invention is limited to these descriptions. For ordinary technicians in the technical field to which the present invention belongs, several simple deductions or substitutions can be made without departing from the concept of the present invention, which should be regarded as belonging to the scope of protection determined by the claims submitted for the present invention.

Claims

1. A novel nucleic acid extraction instrument, comprising a protective shell (1), characterized in that: The front side of the protective shell (1) is provided with a groove (2), the top of the groove (2) is fixedly connected to an electric slide rail (24), the bottom of the electric slide rail (24) is slidably connected to an electric push rod (3) via a slider, the bottom end of the electric push rod (3) is fixedly connected to a connection box (13), the vertical center line of the connection box (13) coincides with the center axis of the electric push rod (3), the bottom of the connection box (13) is fixedly connected to a plurality of magnetic rods (5), and the plurality of magnetic rods (5) are fixedly connected to the bottom of the connection box (13). ) are fixedly connected to the outer side of the magnetic rod body (5), the central axis of the magnetic rod body (5) coincides with the central axis of the detection ring (4), a movable carrier box (6) is arranged at the bottom of the groove (2), a plurality of reagent strips (7) are arranged inside the carrier box (6), one end of the reagent strip (7) is plugged with a magnetic rod sleeve (8), the top edge of the magnetic rod sleeve (8) is provided with an induction coil (9), and the central axis of the induction coil (9) coincides with the central axis of the magnetic rod sleeve (8).

2. The novel nucleic acid extractor according to claim 1, characterized in that: An extraction component is arranged inside the protective shell (1), a control panel (10) is arranged on the top of the protective shell (1), and a plurality of feet (11) are fixedly connected to the bottom of the protective shell (1), wherein the plurality of feet (11) are symmetrical about the vertical center line of the protective shell (1).

3. The novel nucleic acid extractor according to claim 2 is characterized in that: The plurality of reagent strips (7) are evenly distributed about the horizontal center line of the carrier box (6), the magnetic rod bodies (5) are evenly distributed about the horizontal center line of the connection box (13), and the spacing between two adjacent magnetic rod bodies (5) is equal to the spacing between two adjacent magnetic rod sleeves (8).

4. The novel nucleic acid extractor according to claim 3 is characterized in that: The reagent strip (7) is provided with a plurality of circular grooves for loading solutions, and the plurality of circular grooves are evenly distributed about the long side of the reagent strip (7). The outer dimension of the magnetic rod sleeve (8) matches the inner dimension of the induction coil (9).

5. The novel nucleic acid extractor according to claim 4 is characterized in that: A circular hole plate (12) is arranged on the top of the carrier box (6), and the circular hole plate (12) is plugged into the reagent strip (7). The inner diameter of the circular hole of the circular hole plate (12) matches the outer diameter of the circular groove of the reagent strip (7). The bottom surface of the circular hole plate (12) fits the top surface of the carrier box (6), and the outer size of the circular hole plate (12) matches the outer size of the carrier box (6). A handle (14) is fixedly connected to one side of the circular hole plate (12).

6. The novel nucleic acid extractor according to claim 5 is characterized in that: A plurality of cylinders (23) are provided at the rear end of the carrier box (6), the ends of the cylinders (23) are fixedly connected to the protective shell (1), and the plurality of cylinders (23) are symmetrical about the vertical center line of the carrier box (6). A plurality of guide rails (15) are provided at the bottom of the groove (2), and the guide rails (15) are slidably connected to the carrier box (6) via sliders. The guide rails (15) are symmetrical about the vertical center line of the carrier box (6), and two sides of the carrier box (6) are in contact with the inner wall of the groove (2).

7. The novel nucleic acid extractor according to claim 6 is characterized in that: A heater (16) is provided at the front end of the carrier box (6); the heater (16) is communicated with the interior of the carrier box (6); and the horizontal center line of the heater (16) coincides with the horizontal center of the carrier box (6).

8. The novel nucleic acid extractor according to claim 7 is characterized in that: A flip cover (17) is provided at the bottom of the front end of the protective shell (1), one side of the flip cover (17) is rotatably connected to the protective shell (1) via a hinge, and one side of the flip cover (17) is fixedly connected to a sealing ring (18), and the outer size of the sealing ring (18) matches the inner size of the groove (2).

9. The novel nucleic acid extractor according to claim 8, characterized in that: Both sides of the protective shell (1) are provided with a plurality of heat dissipation holes (19), the plurality of heat dissipation holes (19) are distributed in a rectangular array on the side of the protective shell (1), the rear side of the protective shell (1) is fixedly connected with a heat dissipation fan (20), and the back side of the heat dissipation fan (20) is a mesh structure.

10. The novel nucleic acid extractor according to claim 9, characterized in that: A connecting wire (21) is fixedly connected to the rear side of the protective shell (1), a horn tube (22) is provided at the connection between the protective shell (1) and the connecting wire (21), and the horn tube (22) and the protective shell (1) are fixedly connected.

Citation Information

Patent Citations

  • Nucleic acid extractor

    CN222139067U