A tablet hardness testing device

Abstract

The present invention relates to a hardness detection device for tablet drugs applied in the technical field of hardness detection, including a device table, a placement groove, a soaking tray, tablets, a hardness detection module, a coating film, a lifting module, and a pressing cylinder. In the present invention, the tablets are placed in the soaking tray for soaking to simulate the softening of the tablets in the human body. Then, the lifting module drives the pressing cylinder to descend, pressing the coating film on the upper surface of the tablets, thereby effectively improving the fixing effect of the softened tablets, effectively avoiding the damage to the tablets caused by the existing rigid clamping structure, facilitating the hardness detection module to detect the hardness of the tablets, and separating the probe of the hardness detection module from the tablets through the coating film, effectively preventing the softened medicinal mud from adhering to the probe of the hardness detection module, facilitating the cleaning and arrangement of the hardness detection module. The coating film is transmitted from the film release wheel to the film winding wheel, realizing the rapid replacement of the coating film, thereby effectively improving the efficiency of tablet hardness detection.

Description

Technical Field

[0001] A hardness detection device involved in the present invention, in particular, a hardness detection device for tablet drugs applied to the technical field of hardness detection technology. Background Art

[0002] Sustained-release tablets are a type of pharmaceutical preparation designed to release drugs slowly and continuously in the body to extend the drug's action time, reduce the frequency of drug administration, improve patient compliance, and reduce side effects. Hardness is one of the important parameters for tablet quality control. If the tablets are too hard, they may be difficult to break, thus affecting drug release and absorption.

[0003] The specification of Chinese invention patent CN202420347233.8 discloses "A Tablet Hardness Tester with a Structure for Preventing Tablet Displacement". By operating the drive motor, the gear can be driven to rotate, thereby driving two racks, two support plates, two connecting plates, and two clamping frames to move simultaneously and at the same speed in opposite or relative directions, enabling clamping treatment of the tablets, facilitating operation and control, and improving stability during hardness detection.

[0004] In the moist digestive system, the tablets will swell due to the digestive environment. Therefore, it is necessary to detect the hardness of the tablets in a moist environment and then design the drug release effect of the tablets at different time periods. After the tablets are soaked, the outermost periphery of the tablets will swell, and at this time, the tablets cannot be positioned and fixed by clamping, which affects the hardness detection efficiency of the tablets. Summary of the Invention

[0005] Aiming at the above-mentioned prior art, the technical problem to be solved by the present invention is that after the tablets are soaked, the outermost periphery of the tablets will swell, and at this time, the tablets cannot be positioned and fixed by clamping, which affects the hardness detection efficiency of the tablets.

[0006] To solve the above problems, the present invention provides a hardness detection device for tablet drugs, including a device table. A placement groove is opened at the top of the device table, and an immersion tray is placed inside the placement groove. The immersion tray is in a long strip shape, and a plurality of tablets are sequentially placed inside the immersion tray. A detection bracket is slidably connected to the top of the rear end of the device table, and a hardness detection module is fixedly connected to the top of the detection bracket. The probe of the hardness detection module corresponds vertically to the tablets;

[0007] A coating film is transmitted between the probe of the hardness detection module and the tablets. A lifting module is fixedly connected to the outside of the detection bracket, and a pressing cylinder is fixedly connected to the movable end of the lifting module. The bottom end of the pressing cylinder contacts the upper surface of the coating film, and the inner diameter of the pressing cylinder is larger than the diameter of the tablets;

[0008] A film releasing wheel is rotatably connected to the back of the detection bracket. A synchronous bracket is fixedly connected to the bottom of the detection bracket. The front end of the synchronous bracket extends to the front bottom of the device table, and a film winding wheel is rotatably connected to the front end of the synchronous bracket. The coated film is transmitted between the film winding wheel and the film releasing wheel.

[0009] In the above tablet hardness detection device, multiple tablets are successively soaked in the soaking tray. The soaked tablets are covered and fixed by the coated film, so that the hardness detection module can detect the hardness of the softened tablets, and at the same time keep the probe on the hardness detection module clean.

[0010] As a further improvement of the present application, elastic pieces are fixedly connected to both the left and right ends of the bottom of the pressing cylinder. A lining ring is fixedly connected between the bottom ends of the two elastic pieces. The lining ring is located on the lower surface of the coated film. The lining ring is vertically corresponding to the pressing cylinder, and the inner diameter of the lining ring is the same as that of the pressing cylinder. During the process of the pressing cylinder pressing down the coated film, the lining ring contacts the bottom of the soaking tray first, and then the coated film is clamped and fixed by the pressing cylinder and the lining ring, effectively improving the covering stability of the coated film on the tablets.

[0011] As a further improvement of the present application, the elastic piece is bent in a U shape and is made of spring steel sheet, and the lining ring is made of stainless steel material. The elastic effect of the elastic piece is used to automatically push open the pressing cylinder and the lining ring, facilitating the transmission of the coated film between the pressing cylinder and the lining ring.

[0012] As a further improvement of the present application, a hollow groove is formed in the middle of the elastic piece. Fixed hole pages and limit bolts are respectively fixedly connected to the top and bottom of the hollow groove. The limit bolt penetrates through the fixed hole page, and a nut is threadedly connected to the top of the limit bolt. The nut is located on the upper surface of the fixed hole page. The maximum expansion degree of the elastic piece is limited by the limit bolt, so that the lining ring provides support for the transmitted coated film, effectively improving the transmission stability effect of the coated film.

[0013] As another improvement of the present application, a cleaning fluff piece is fixedly inlaid at one end of the upper surface of the lining ring corresponding to the output direction of the coated film. The cleaning fluff piece is in sliding contact with the lower surface of the coated film. When the coated film slides on the lining ring, the lower surface of the coated film is cleaned by the cleaning fluff piece. The main cleaning object is the softened medicine mud, so as to avoid the medicine mud contaminating the detection environment along with the transmission of the coated film.

[0014] As a further improvement supplement of the present application, an arch arm is fixedly connected to the top of the front end of the synchronization bracket. A film pressing strip is fixedly connected to one end of the arch arm away from the synchronization bracket. The upper surface of the cleaning fluff sheet is higher than the lower surface of the film pressing strip. The lower surface of the film pressing strip is slidably connected to the covering film. The film pressing strip is used to apply a downward pressure on the covering film, improving the contact effect between the covering film and the cleaning fluff sheet on the lining ring, thereby improving the cleaning effect of the cleaning fluff sheet on the mud on the lower surface of the covering film.

[0015] As a further improvement supplement of the present application, transverse brackets are fixedly connected to both the left and right ends of the arch arm. Tension springs are fixedly connected to both ends of the transverse bracket. A film drum sheet is fixedly connected between the bottom ends of the two tension springs. The film drum sheet is slidably connected to the lower surface of the covering film. The film drum sheet is used to provide an arched support for the covering film before winding, providing a buffer for the downward pressure of the covering film, thereby preventing the covering film from being overstretched and deformed due to the downward pressure, and effectively avoiding the subsequent transmission and replacement of the covering film.

[0016] As yet another improvement of the present application, one end of the film drum sheet is hinged to the front end of the synchronization bracket, and the other end of the film drum sheet is vertically corresponding to the film pressing strip, effectively improving the flipping motion stability of the film drum sheet and at the same time restricting the maximum flipping angle of the film drum sheet.

[0017] In summary, in the present invention, the tablets are placed in the soaking tray for soaking to simulate the softening of the tablets in the human body. When detecting the hardness of the softened tablets, the lifting module drives the pressing cylinder to descend, pressing the covering film on the upper surface of the tablets, thereby effectively improving the fixing effect of the softened tablets, effectively avoiding the damage to the tablets caused by the existing rigid clamping structure, facilitating the hardness detection module to detect the hardness of the tablets, and separating the probe of the hardness detection module from the tablets through the covering film, effectively preventing the softened mud from adhering to the probe of the hardness detection module, facilitating the cleaning and arrangement of the hardness detection module. The covering film is transmitted from the film releasing wheel to the film winding wheel, realizing the rapid replacement of the covering film, thereby effectively improving the efficiency of tablet hardness detection. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 It is a three-dimensional structure diagram of the first embodiment of the present application;

[0019] Figure 2 It is a three-dimensional structure diagram of the soaking tray and the tablets of the first embodiment of the present application;

[0020] Figure 3 It is a plane cross-sectional view of the soaking tray and the pressing cylinder of the first embodiment of the present application;

[0021] Figure 4 It is a demonstration diagram of the covering film wrapping the tablets of the first embodiment of the present application;

[0022] Figure 5 Stereoscopic structure diagram of the synchronous support in the first implementation mode of this application;

[0023] Figure 6 Enlarged view of the elastic sheet in the first implementation mode of this application;

[0024] Figure 7 Stereoscopic structure diagram of the gasket in the first implementation mode of this application;

[0025] Figure 8 Demonstration diagram of the cleaning felt piece cleaning the coating film in the second implementation mode of this application;

[0026] Figure 9 Demonstration diagram of the gasket immersed in the soaking tray in the second implementation mode of this application;

[0027] Figure 10 Stereoscopic structure diagram of the film drum piece of the arch arm box in the second implementation mode of this application;

[0028] Figure 11 Demonstration diagram of the film drum piece being pressed, flipped and lowered in the second implementation mode of this application.

[0029] Explanation of the reference numerals in the figure:

[0030] 1. Device table; 101. Placing groove; 102. Soaking tray; 103. Detection support; 104. Hardness detection module; 2. Tablet; 3. Coating film; 301. Lifting module; 302. Rolling cylinder; 303. Film release wheel; 304. Synchronous support; 305. Film winding wheel; 4. Gasket; 401. Elastic sheet; 402. Hollow groove; 403. Fixed hole page; 404. Limit bolt; 405. Nut; 406. Cleaning felt piece; 5. Arch arm; 501. Film pressing strip; 502. Horizontal support; 503. Tension spring; 504. Film drum piece. Specific implementation mode

[0031] The following will make a detailed description of the two implementation modes of this application with reference to the accompanying drawings.

[0032] The first implementation mode:

[0033] Figures 1 to 2 As shown, a tablet hardness detection device includes a device table 1. A placing groove 101 is opened at the top of the device table 1. An soaking tray 102 is placed inside the placing groove 101. The soaking tray 102 is in a long strip shape, and a plurality of tablets 2 are sequentially placed inside the soaking tray 102. The detection support 103 is slidably connected to the top of the rear end of the device table 1. The hardness detection module 104 is fixedly connected to the top of the detection support 103. The probe of the hardness detection module 104 is vertically corresponding to the tablet 2;

[0034] When measuring the hardness of the softened tablets 2, first pour a simulated solution into the soaking tray 102, which is used to simulate the moist environment of the digestive tract. Then, put multiple tablets 2 into the soaking tray 102 in sequence, and place the soaking tray 102 in the placement groove 101 for static placement. After soaking for a specified time, operate the hardness detection module 104 to measure the hardness of the softened tablets 2 in the soaking tray 102 in sequence. The detection interval between adjacent two tablets 2 can also be set to increase the soaking time of the tablets 2 in sequence. The hardness detection module 104 also measures the tablets 2 with different soaking degrees in sequence, effectively improving the hardness detection efficiency of the tablets 2.

[0035] Figures 1 to 5 As shown, a coating film 3 is transmitted between the probe of the hardness detection module 104 and the tablet 2. An elevating module 301 is fixedly connected to the outside of the detection bracket 103. The movable end of the elevating module 301 is fixedly connected to an expanding cylinder 302. The bottom end of the expanding cylinder 302 contacts the upper surface of the coating film 3, and the inner diameter of the expanding cylinder 302 is larger than the diameter of the tablet 2. A film releasing wheel 303 is rotatably connected to the back of the detection bracket 103. A synchronous bracket 304 is fixedly connected to the bottom of the detection bracket 103. The front end of the synchronous bracket 304 extends to the bottom of the front end of the device table 1, and a film winding wheel 305 is rotatably connected to the front end of the synchronous bracket 304. The coating film 3 is transmitted between the film winding wheel 305 and the film releasing wheel 303.

[0036] Before fixing and detecting the softened tablets 2, the coating film 3 is transmitted from the film releasing wheel 303 to the film winding wheel 305, so that the coating film 3 is transmitted to the top of the tablet 2. The elevating module 301 drives the expanding cylinder 302 to descend, and the expanding cylinder 302 presses the coating film 3 to cover the top of the tablet 2, realizing the covering and fixing of the tablet 2, effectively reducing the damage to the softened tablet 2. Then, the probe of the hardness detection module 104 indirectly applies pressure to the tablet 2 through the coating film 3, thereby detecting the hardness of the tablet 2. The coating film 3 separates the probe of the hardness detection module 104 and the tablet 2, effectively preventing the softened medicine mud from adhering to the probe of the hardness detection module 104 and facilitating the cleaning and arrangement of the hardness detection module 104.

[0037] Figure 1 and Figures 4 to 7It is shown that elastic pieces 401 are fixedly connected to both the left and right ends of the bottom of the pressing cylinder 302. A lining ring 4 is fixedly connected between the bottom ends of the two elastic pieces 401. The lining ring 4 is located on the lower surface of the covering film 3. The lining ring 4 is vertically corresponding to the pressing cylinder 302, and the inner diameter of the lining ring 4 is the same as that of the pressing cylinder 302. During the process of the pressing cylinder 302 pressing down the covering film 3, the lining ring 4 contacts the bottom of the soaking tray 102 first, and then the pressing cylinder 302 and the lining ring 4 clamp and fix the covering film 3, effectively improving the covering stability of the covering film 3 on the tablets. The elastic piece 401 is arranged in a U-shaped bend and is made of spring steel sheet. The lining ring 4 is made of stainless steel material. The elastic effect of the elastic piece 401 is used to automatically push open the pressing cylinder 302 and the lining ring 4, facilitating the transmission of the covering film 3 between the pressing cylinder 302 and the lining ring 4;

[0038] During the process of the pressing cylinder 302 pushing the covering film 3 down, the lining ring 4 contacts the bottom of the soaking tray 102 first, and then the pressing cylinder 302 continues to descend. The U-shaped bent elastic piece 401 is bent and folded and deformed. Finally, the pressing cylinder 302 and the lining ring 4 clamp and fix the covering film 3, effectively improving the covering stability of the covering film 3 on the tablets. When the pressing cylinder 302 does not press down the covering film 3, the pressing cylinder 302 and the lining ring 4 are separated and pushed open by the elastic piece 401, facilitating the transmission of the covering film 3 between the pressing cylinder 302 and the lining ring 4.

[0039] The second implementation mode:

[0040] Compared with the first implementation mode, a cleaning fluff piece 406 is mainly added. The specific added structure is as follows, and the rest of the structures are the same as those of the first implementation mode.

[0041] Figures 6 to 9 It is shown that a cleaning fluff piece 406 is fixedly inlaid at one end of the upper surface of the lining ring 4 corresponding to the output direction of the covering film 3. The cleaning fluff piece 406 is in sliding contact with the lower surface of the covering film 3. When the covering film 3 slides on the lining ring 4, the cleaning fluff piece 406 is used to clean the lower surface of the covering film 3. The main cleaning object is the softened medicinal mud, thus avoiding the pollution of the detection environment by the medicinal mud following the transmission of the covering film 3. A hollow-out groove 402 is formed in the middle of the elastic piece 401. A fixing hole page 403 and a limit bolt 404 are fixedly connected to the top and bottom of the hollow-out groove 402 respectively. The limit bolt 404 penetrates through the fixing hole page 403. A nut 405 is threadedly connected to the top of the limit bolt 404. The nut 405 is located on the upper surface of the fixing hole page 403. The maximum expansion degree of the elastic piece 401 is restricted by the limit bolt 404, so as to realize the support of the lining ring 4 for the transmitted covering film 3 and effectively improve the transmission stability effect of the covering film 3;

[0042] When the coating film 3 is transmitted between the embossing cylinder 302 and the gasket 4, the lower surface of the coating film 3 is in sliding contact with the cleaning fluff 406 on the gasket 4, so as to clean the medicinal mud attached to the lower surface of the coating film 3. This medicinal mud adheres when the coating film 3 covers the tablet 2. After cleaning, the coating film 3 is more convenient for the winding and recycling of the film winding wheel 305. When the embossing cylinder 302 pushes the coating film 3 downward, the gasket 4 sinks into the soaking tray 102 one step earlier, so that the cleaning fluff 406 on the gasket 4 is immersed in the solution in the soaking tray 102, so that the medicinal mud on the cleaning fluff 406 scatters, realizing the automatic cleaning of the cleaning fluff 406 and facilitating the repeated use of the cleaning fluff 406.

[0043] Figure 3 and Figures 10 to 11 As shown, a cambered arm 5 is fixedly connected to the top of the front end of the synchronous bracket 304. One end of the cambered arm 5 away from the synchronous bracket 304 is fixedly connected with a film pressing strip 501. The upper surface of the cleaning fluff 406 is higher than the lower surface of the film pressing strip 501. The lower surface of the film pressing strip 501 is slidably connected with the coating film 3. The film pressing strip 501 is used to apply a downward pressure on the coating film 3 to improve the contact effect between the coating film 3 and the cleaning fluff 406 on the gasket 4, so as to improve the cleaning effect of the cleaning fluff 406 on the medicinal mud on the lower surface of the coating film 3. Transverse brackets 502 are fixedly connected to both the left and right ends of the cambered arm 5. Tension springs 503 are fixedly connected to both ends of the transverse brackets 502. A film drum piece 504 is fixedly connected between the bottom ends of the two tension springs 503. The film drum piece 504 is slidably connected with the lower surface of the coating film 3. The coating film 3 before winding is arched and supported by the film drum piece 504 to provide a buffer for the downward pressure of the coating film 3, so as to prevent the coating film 3 from being over-stretched and deformed due to the downward pressure, thus effectively avoiding the subsequent transmission and replacement of the coating film 3. One end of the film drum piece 504 is hinged to the front end of the synchronous bracket 304, and the other end of the film drum piece 504 is vertically corresponding to the film pressing strip 501, effectively improving the flipping motion stability of the film drum piece 504 and at the same time limiting the maximum flipping angle of the film drum piece 504;

[0044] When the coating film 3 is transmitted between the embossing cylinder 302 and the gasket 4, the film pressing strip 501 on the cambered arm 5 is used to apply a downward pressure on the coating film 3, effectively increasing the contact pressure between the coating film 3 and the cleaning fluff 406, so as to effectively improve the cleaning effect of the lower surface of the coating film 3. The coating film 3 is arched and supported by the film drum piece 504, that is, the transmission length of the coating film 3 is extended. When the coating film 3 is pressed downward, the longer coating film 3 can better buffer the tension caused by the tightness, so as to effectively prevent the coating film 3 from being over-stretched and deformed due to the downward pressure, facilitating the subsequent transmission and replacement of the coating film 3.

[0045] Combined with the current actual requirements, the above-mentioned implementation manner adopted in this application, the scope of protection is not limited thereto. Within the scope of knowledge possessed by those skilled in the art, various changes made without departing from the concept of this application still fall within the scope of protection of the present invention.

Claims

1. A tablet hardness detection device, characterized in that: It includes a device table (1), a placement groove (101) is formed at the top of the device table (1), an immersion tray (102) is placed inside the placement groove (101), the immersion tray (102) is in a long strip shape, and a plurality of tablets (2) are sequentially placed inside the immersion tray (102). A detection bracket (103) is slidably connected to the top of the rear end of the device table (1), a hardness detection module (104) is fixedly connected to the top of the detection bracket (103), and the probe of the hardness detection module (104) is vertically corresponding to the tablet (2). A coating film (3) is transmitted between the probe of the hardness detection module (104) and the tablet (2). A lifting module (301) is fixedly connected to the outside of the detection bracket (103), a pressing cylinder (302) is fixedly connected to the movable end of the lifting module (301), the bottom end of the pressing cylinder (302) is in contact with the upper surface of the coating film (3), and the inner diameter of the pressing cylinder (302) is larger than the diameter of the tablet (2). A film release wheel (303) is rotatably connected to the back of the detection bracket (103), a synchronous bracket (304) is fixedly connected to the bottom of the detection bracket (103), the front end of the synchronous bracket (304) extends to the bottom of the front end of the device table (1), and a film winding wheel (305) is rotatably connected to the front end of the synchronous bracket (304). The coating film (3) is transmitted between the film winding wheel (305) and the film release wheel (303). Elastic pieces (401) are fixedly connected to both the left and right ends of the bottom of the pressing cylinder (302). A gasket (4) is fixedly connected between the bottom ends of the two elastic pieces (401). The gasket (4) is located on the lower surface of the coating film (3). The gasket (4) is vertically corresponding to the pressing cylinder (302), and the inner diameter of the gasket (4) is the same as that of the pressing cylinder (302). The elastic piece (401) is bent in a U shape and is made of spring steel sheet. The gasket (4) is made of stainless steel material. A hollow groove (402) is formed in the middle of the elastic piece (401). Fixed hole pages (403) and limit bolts (404) are respectively fixedly connected to the top and bottom of the hollow groove (402). The limit bolt (404) penetrates through the fixed hole page (403), and a nut (405) is threadedly connected to the top of the limit bolt (404). The nut (405) is located on the upper surface of the fixed hole page (403).

2. The hardness detection device for tablet drugs according to claim 1, wherein: A cleaning fluff piece (406) is fixedly inlaid at one end of the upper surface of the gasket (4) corresponding to the output direction of the coating film (3). The cleaning fluff piece (406) is in sliding contact with the lower surface of the coating film (3).

3. The hardness detection device for tablet drugs according to claim 2, characterized in that: An arch arm (5) is fixedly connected to the top of the front end of the synchronous bracket (304). A film pressing strip (501) is fixedly connected to the end of the arch arm (5) away from the synchronous bracket (304). The upper surface of the cleaning fluff piece (406) is higher than the lower surface of the film pressing strip (501). The lower surface of the film pressing strip (501) is in sliding connection with the coating film (3).

4. The hardness detection device for tablet drugs according to claim 3, wherein: Both the left and right ends of the arch arm (5) are fixedly connected with transverse brackets (502). Both ends of the transverse brackets (502) are fixedly connected with tension springs (503). A film drum piece (504) is fixedly connected between the bottom ends of the two tension springs (503). The film drum piece (504) is slidably connected with the lower surface of the coating film (3).

5. The hardness detection device for tablet drugs according to claim 4, characterized in that: One end of the film drum piece (504) is hinged to the front end of the synchronous bracket (304), and the other end of the film drum piece (504) is vertically corresponding to the film pressing strip (501).

Images