Peripheral circulation function evaluation device

Abstract

The invention relates to the technical field of medical instruments, and discloses a peripheral circulation function evaluation device, which comprises a control system and a finger fixing seat, and is characterized in that the control system is used for carrying out driving control on a pressure generator and analyzing a shooting result of a camera; the control system can accurately set and evaluate the required pressing pressure value and pressing time, and analyzes the color change of the nail bed before pressing, during pressing and after pressing. The electromagnetic pressure is accurately regulated and controlled, torsion deformation of the spring is restrained by combining a limiting structure, linear pressure output in the vertical direction is achieved, the pressure value is determined according to the quantitative relation between the electromagnet distance and the current, and errors are reduced; a dynamic buffer mechanism forms a progressive loading curve when pressure is applied, so that the instantaneous impact pressure is prevented from exceeding a tolerance threshold value of an assessed person; optical synchronous acquisition is realized, and interference of skin color on blood oxygen saturation calculation is eliminated in a dual-wavelength narrow-band filtering mode.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and particularly relates to a device for evaluating peripheral circulation function. Background Art

[0002] Peripheral circulation refers to the blood circulation between arterioles and venules, which is the most distal part of the entire blood circulation system. This part of the circulation mainly involves the body surface and the extremities of the human body, including the blood vessel networks in parts such as the skin, fingers, and toes. These tiny blood vessels include small arteries, arterioles, capillaries, venules, and small veins, which are interconnected to form a complex and delicate circulatory system. Capillaries are the core part of peripheral circulation. Their walls are very thin, consisting of only a single layer of endothelial cells, which enables oxygen, nutrients, metabolic wastes, etc. to easily pass through the wall for exchange. Arterioles and venules play a role in regulating the blood flow in capillaries. They can change the blood vessel diameter according to the body's physiological needs, such as exercise and temperature changes, by contracting and relaxing the vascular smooth muscle, thereby controlling the speed of blood entering and leaving capillaries.

[0003] The normal or abnormal function of peripheral circulation can be evaluated from multiple aspects. For example, skin temperature, skin color, and capillary refill time (CRT) are all commonly used observation indicators. Under normal circumstances, the skin temperature at the extremities of the limbs should remain relatively stable, the skin color should be rosy, and the CRT should be within 2 seconds. If there is a disorder in peripheral circulation function, it may lead to a decrease in skin temperature, abnormal skin color (such as pallor or cyanosis), an extension of CRT, etc. In severe cases, it may even cause multiple organ failure and endanger life.

[0004] In clinical practice, the traditional method for measuring CRT is to evaluate the peripheral circulation function by observing the time for the skin at the extremity to return to its color after manual compression. However, this method has certain subjectivity and limitations. In recent years, with the development of bioelectrical impedance detection technology, new ideas and methods have been provided for the evaluation of peripheral circulation function. Bioelectrical impedance detection can more objectively and accurately reflect the blood circulation status by measuring the impedance changes of tissues or organs to electric current.

[0005] There is a disclosed device for evaluating peripheral circulation function based on bioelectrical impedance detection in the prior art, with the application number CN202210053819.9, including an airbag finger sleeve, electrodes, an air pump, and a control and evaluation device. Compared with other detection devices, this device innovatively uses the impedance detection method, and the results are reliable; its structure is simple, the operation is convenient, and it is not affected by the use environment; in addition to being applicable to conventional patients, it can also be applicable to patients with poor cooperation ability such as critically ill patients and newborns. However, the prior art, especially this solution, still has the following problems:

[0006] 1. Defects in the pressure application mechanism: The airbag pressure control relies on the airtightness of the air pump. After long-term use, pressure drift is likely to occur due to rubber aging. There is a lack of a limiting structure. When structures such as the airbag expand, a lateral offset force is generated, causing the pressure direction to deviate from the normal direction of the nail bed and resulting in uneven compression of capillaries.

[0007] 2. Lack of dynamic process monitoring: It can only provide static impedance values and cannot record the dynamic response process of microcirculation during the pressing and releasing periods. The pressure application and signal acquisition are asynchronous, resulting in insufficient time resolution and inability to establish a multi-dimensional correlation model of pressure-impedance-time.

[0008] 3. In addition, there is also insufficient skin color adaptability. The electrical impedance signal is significantly affected by the thickness of the stratum corneum of the skin. The detection misjudgment rate of patients with dark skin (Fitzpatrick type Ⅳ-Ⅵ) is high, and it cannot meet the universality requirements for multi-skin-color populations. Summary of the Invention

[0009] The purpose of the present invention is to provide a technical solution to establish a more accurate and quantitative pressure application mechanism, provide detection of the dynamic process, and improve skin color adaptability through a control system combined with an AI algorithm to solve the problems in the prior art mentioned in the above background technology.

[0010] To achieve the above purpose, the present invention adopts the following technical solutions:

[0011] A peripheral circulation function evaluation device includes:

[0012] A control system and a finger fixing seat. The finger fixing seat is provided with a placement cavity for the tester's finger to be placed. The finger fixing seat is provided with a pressure generator for pressing the finger inside the placement cavity for evaluation. A camera is provided at the bottom of the pressure generator.

[0013] The control system is used to drive and control the pressure generator and analyze the shooting results of the camera. The control system can accurately set the pressure value and pressing time required for evaluation, and at the same time analyze the color change of the nail bed before, during, and after pressing.

[0014] Preferably, the pressure generator includes a housing. A spring is provided inside the housing, and a positioning structure is provided inside the housing for preventing the spring from undergoing torsional deformation when expanding and contracting inside the housing.

[0015] Preferably, the spring is set as spring one. The positioning structure includes a limiting groove and a limiting post. The limiting groove is opened on the housing, and the opening direction of the limiting groove is the expansion and contraction direction of spring one. The limiting posts are connected to both ends of spring one, and the limiting posts slide inside the limiting groove.

[0016] Preferably, an electromagnet is used for pressure driving in the pressure generator. The pressure generator includes an electromagnet I and an electromagnet II. A spring I is arranged between the electromagnet I and the electromagnet II and serves as a reset structure for the two.

[0017] Preferably, the spring I is installed between the two electromagnets in a stretched state. The housing is arranged in a structure with an opening facing downward. The electromagnet I is installed at the inner top of the housing. Under the electromagnetic force of opposite-sex repulsion between the electromagnet I and the electromagnet II, the electromagnet II is driven by the electromagnetic force to provide a downward pressure.

[0018] Preferably, a transparent cover is arranged at the bottom of the pressure generator. The transparent cover is used to contact the finger to provide a downward pressure. A camera is arranged inside the transparent cover. A spring II is arranged between the electromagnet II and the transparent cover.

[0019] Preferably, a sleeve is slidably installed inside the housing. The transparent cover is slidably installed inside the sleeve. The spring II is arranged inside the sleeve and supports between the inner bottom of the sleeve and the transparent cover.

[0020] Preferably, a detachable cover plate is arranged on the transparent cover. A shooting groove for camera installation is arranged inside the transparent cover. The groove surface of the shooting groove on the side of the camera viewfinder is set as a smooth plane to meet the shooting and viewfinder needs of the camera.

[0021] Preferably, an installation hole for installing the pressure generator is arranged on the finger fixing seat. The transparent cover also passes through the installation hole. An observation groove hole is arranged at one end of the finger fixing seat where the pressure generator is located. The observation groove hole is used to observe whether the finger is placed in the correct position.

[0022] Preferably, it further includes a multi-modal peripheral circulation dynamic quantization evaluation method, including the following steps:

[0023] Step S1, multi-spectral dynamic calibration: hardware linkage control, skin color adaptive optical correction;

[0024] Step S2, phase change feature extraction: capillary network modeling, critical state monitoring;

[0025] Step S3, quantization feature encoding: color space dimension elevation, quantum principal component analysis;

[0026] Step S4, multi-modal adversarial training: pathological data generation, spectral discriminator optimization.

[0027] The technical effects and advantages of the present invention: An end-circulation function evaluation device proposed by the present invention has the following advantages compared with the prior art:

[0028] Through precise electromagnetic pressure regulation, the present invention combines a limiting structure to inhibit the torsional deformation of the spring, achieving linear pressure output in the vertical direction. The pressure value is determined by the quantitative relationship between the distance between the electromagnets and the current, reducing the error. A dynamic buffering mechanism forms a progressive loading curve when applying pressure, avoiding the instantaneous impact pressure exceeding the tolerance threshold of the evaluated person. Optical synchronous acquisition eliminates the interference of skin color on the calculation of blood oxygen saturation in the dual-wavelength narrowband filtering mode. BRIEF DESCRIPTION OF THE DRAWINGS

[0029] Figure 1 is a schematic structural diagram of the peripheral circulation function evaluation device of the present invention;

[0030] Figure 2 of the present invention Figure 2 is an enlarged schematic structural diagram of part A in the present invention;

[0031] Figure 3 is a schematic diagram of the structure of the first spring and other components in an embodiment of the present invention;

[0032] Figure 4 is a schematic cross-sectional structural diagram of the peripheral circulation function evaluation device of the present invention;

[0033] Figure 5 is a schematic internal structural diagram of the pressure generator of the present invention.

[0034] In the figure:

[0035] 11. Finger fixing seat; 12. Insertion cavity; 13. Observation slot hole; 14. Mounting hole; 15. Pressure generator; 16. Outer shell; 17. First spring; 18. Sleeve; 19. Second spring; 110. Camera; 111. Transparent cover; 112. First electromagnet; 113. Second electromagnet; 114. Limiting groove; 115. Limiting post; 116. Cover plate; 117. Shooting slot; 118. Battery. DETAILED DESCRIPTION OF THE EMBODIMENTS

[0036] Now, the subject matter described herein will be discussed with reference to exemplary embodiments. It should be understood that discussing these embodiments is only to enable those skilled in the art to better understand and thus implement the subject matter described herein. Without departing from the scope of protection of the content of this specification, changes can be made to the functions and arrangements of the elements discussed. Each example can omit, substitute, or add various processes or components as needed. Additionally, the features described in some examples can also be combined in other examples.

[0037] Peripheral circulation refers to the blood circulation between arterioles and venules. It is the most distal part of the entire blood circulation system. This part of the circulation mainly involves the body surface and the extremities of the human body, including the vascular networks in areas such as the skin, fingers, and toes. These tiny blood vessels include small arteries, arterioles, capillaries, venules, and small veins, which are interconnected to form a complex and delicate circulatory system. Capillaries are the core part of peripheral circulation. Their walls are very thin, consisting of only a single layer of endothelial cells, which allows oxygen, nutrients, metabolic wastes, etc. to easily exchange through the walls. Arterioles and venules play a role in regulating the blood flow in capillaries. They can, according to the body's physiological needs, such as exercise and temperature changes, change the blood vessel diameter through the contraction and relaxation of vascular smooth muscle, thereby controlling the speed of blood entering and leaving capillaries.

[0038] In critically ill patients, changes in the peripheral circulation status are often early signs of disease progression. The current methods for examining the peripheral circulation in critically ill patients are as follows:

[0039] Inspection by observing skin color changes: Normal skin color is rosy, indicating good blood circulation. If the skin appears pale, it may be due to constriction of peripheral blood vessels and reduced blood perfusion. Cyanosis refers to the bluish-purple change in the skin and mucous membranes, mostly caused by an increase in reduced hemoglobin in the blood, suggesting insufficient oxygenation in peripheral circulation, which may be caused by cardiopulmonary dysfunction or local vascular obstruction, etc. Mottled changes, that is, the skin shows an irregular pattern of red and white, are usually manifestations of severe peripheral circulation disorders, indicating severely insufficient microcirculation perfusion. However, inspection has the following limitations. Subjectivity is strong: The observation of skin color is an important part of inspection, but it has strong subjectivity. Different examiners' judgments on whether the skin color is normal, the degree of cyanosis or mottling may vary due to factors such as individual visual differences and environmental light. For example, in a dimly lit environment, the true skin color may be misjudged, leading to an incorrect assessment of the peripheral circulation status. There are many interfering factors: Skin color is also affected by the skin's own pigmentation. For patients with darker skin tones, it is more difficult to observe skin color changes to judge whether the peripheral circulation is abnormal. Slight cyanosis may be difficult to detect because the darker skin color itself will mask this color change. In addition, local skin lesions, such as rashes and ecchymoses, may also interfere with the accurate judgment of the peripheral circulation status.

[0040] Temperature check: Feel the temperature of the patient's fingertips, toes and other peripheral parts with your hands. Under normal circumstances, these parts should be warm. If they feel cold, it usually indicates poor peripheral circulation, which may be due to low environmental temperature, vasoconstriction or shock. When checking the patient's temperature, the temperature of the examiner's hand will affect the result. If the examiner's own hand is relatively cold, the temperature of the patient's limb may be overestimated; conversely, if the examiner's hand is relatively hot, the temperature of the patient's limb may be underestimated. Moreover, this method can only provide a general temperature feeling and cannot accurately measure the degree of temperature change.

[0041] Instrument examination: 1. Pulse oximetry (SpO2): By clamping a pulse oximeter on the patient's finger or toe, etc., the oxygen saturation of the peripheral part can be continuously monitored. It uses the absorption characteristics of hemoglobin for specific wavelengths of light to measure oxygen saturation; 2. Laser Doppler flowmeter: This instrument can measure the blood flow velocity of skin microcirculation. It uses the laser Doppler effect. When laser irradiates moving red blood cells in skin tissue, the frequency of the reflected light will change, and the blood flow velocity is calculated by detecting this frequency change. The above instrument examination methods have the following disadvantages: 1. Strong dependence on equipment; 2. Wire entanglement; 3. High price; 4. Certain limitations in use.

[0042] The capillary refill time (CRT, capillary refill time) of peripheral circulation is the most convenient and commonly used observation index for evaluating peripheral circulation function. CRT refers to the time required for the color to return to normal after pressing the skin to empty the blood in the local capillary bed. This is a simple and commonly used method for evaluating the state of peripheral circulation. Usually, press the finger or toenail bed and observe the time from turning white to returning to a rosy color. In 2011, the CRT measurement method described in the American Pediatric Advanced Life Support Guidelines was specifically described: Elevate the ends of the limbs above the heart level, press the skin at the end of the limb and then quickly release it, and observe the time required for the skin to return to its original color. Peripheral circulation is a part of the peripheral circulation. Evaluating the peripheral circulation function by using the CRT method at the extremities can reflect the state of microcirculation. Under normal circumstances, the capillary filling time is 2 - 3 seconds. This time indicates that the perfusion and blood flow of peripheral circulation are in a normal state, and the capillaries can be quickly replenished with blood, enabling tissues to obtain oxygen and nutrients in a timely manner. In critically ill patients, when tissue perfusion is insufficient, such as in shock, dehydration, etc., the capillary filling time will be prolonged. This is because the blood perfusion decreases, the peripheral blood vessels constrict, the blood flow in the capillary bed decreases, and the time for the nail bed to return to a rosy color after pressing and releasing will significantly exceed 3 seconds. However, the following factors affect the accuracy of CRT:

[0043] 1. Influence of operation techniques - Pressing force: If the pressing force on the nail bed is too light, it may not be able to completely empty the blood in the capillaries, resulting in false negative results. That is, the actual capillary refill time may be prolonged, but due to the insufficient emptying of blood, the observed refill time is within the normal range. If the pressing force is too heavy, it may damage local tissues or blood vessels, causing local blood circulation disorders, prolonging the refill time, and resulting in false positive results. - Pressing time: The length of the pressing time also affects the result. If the pressing time is too short, the blood in the capillaries is not fully emptied, and a situation similar to too light pressing force will occur, leading to inaccurate results. Generally, it is necessary to press for a sufficient length of time, usually 3 - 5 seconds, until the nail bed turns completely white, so as to ensure accurate measurement of the refill time. - Individual differences: Everyone's refill time is different. Although the CRT examination has certain limitations, as a simple and rapid examination method, it can be combined with other peripheral circulation examination methods to comprehensively evaluate the peripheral circulation status. At the same time, a CRT evaluation device is designed to reduce the influencing factors of the current CRT examination, thereby improving its accuracy.

[0044] Example 1: The invention provides as Figures 1 to 5 shown, a peripheral circulation function evaluation device, including:

[0045] A control system and a finger fixing seat 11. The finger fixing seat 11 is provided with a placement cavity 12 for the tester's finger to be placed. The finger fixing seat 11 is provided with a pressure generator 15. The pressure generator 15 is used to perform the pressing required for the evaluation on the finger inside the placement cavity 12. The bottom of the pressure generator 15 is provided with a camera 110;

[0046] The control system is used to drive and control the pressure generator 15 and to analyze the shooting results of the camera 110; the control system can accurately set the pressure value and pressing time of the pressing required for the evaluation, and at the same time analyze the color changes of the nail bed before, during, and after pressing.

[0047] As Figures 1 to 3 shown, since the pressure generator 15 can adopt various structures as the pressure generation method, no matter which pressure generation structure is used, a spring will be used to a certain extent. However, due to the inherent properties of the spring structure, when the spring is compressed, not only will there be axial expansion and contraction, but the spring will also undergo a certain degree of torsion, especially at both ends of the spring. And this certain degree of torsion will cause inaccurate pressure generated by the pressure generator 15.

[0048] The pressure generator 15 includes a housing 16. A spring is arranged inside the housing 16, and a positioning structure is arranged inside the housing 16. The positioning structure is used to prevent the spring from undergoing torsional deformation when stretching and contracting inside the housing 16. Specifically, the spring is set as the first spring 17. The positioning structure includes a limiting groove 114 and a limiting post 115. The limiting groove 114 is opened on the housing 16, and the opening direction of the limiting groove 114 is the stretching and contracting direction of the first spring 17. The limiting posts 115 are connected to both ends of the first spring 17, and the limiting posts 115 slide inside the limiting groove 114, and the torsional of the spring is suppressed by the corresponding spring stretching and limiting structure.

[0049] As Figure 4 and Figure 5 shown, in order to obtain more accurate pressure generation control, the pressure generator 15 uses an electromagnet for pressure drive. The pressure generator 15 includes a first electromagnet 112 and a second electromagnet 113. The first spring 17 is arranged between the first electromagnet 112 and the second electromagnet 113 and serves as a reset structure for both.

[0050] Specifically, the first spring 17 is installed between the two electromagnets in a stretched state. The housing 16 is set as a structure with an opening facing downwards. The first electromagnet 112 is installed on the inner top of the housing 16. Under the electromagnetic force of opposite-sex repulsion between the first electromagnet 112 and the second electromagnet 113, the second electromagnet 113 is pressed down by the electromagnetic force to provide a downward pressure. In the pressure drive mode provided by the electromagnetic force, by conversion, it can be known the pressure value provided at a certain distance between the electromagnets, which has more accurate pressure control compared to other methods.

[0051] As Figure 4 and Figure 5 shown, in order to avoid the downward pressure exceeding the tolerance limit of the tested person and provide a corresponding buffering function, a transparent cover 111 is arranged at the bottom of the pressure generator 15. The transparent cover 111 is used to contact the finger to provide a downward pressure. A camera 110 is arranged inside the transparent cover 111. A second spring 19 is arranged between the second electromagnet 113 and the transparent cover 111. With the arrangement of the second spring 19, the pressure received by the finger gradually increases to the set value, and the finger will not be subjected to excessive pressure causing discomfort to the tested person.

[0052] As Figure 4 and Figure 5 shown, a sleeve 18 is slidably installed inside the housing 16. The transparent cover 111 is slidably installed inside the sleeve 18. The second spring 19 is arranged inside the sleeve 18 and supports between the inner bottom of the sleeve 18 and the transparent cover 111. A structure for preventing the sleeve 18 from sliding out of the housing 16 is arranged inside the housing 16. Similarly, a structure for preventing the transparent cover 111 from sliding out of the sleeve 18 is arranged inside the sleeve 18.

[0053] As Figure 5As shown in the figure, a detachable cover plate 116 is provided on the transparent cover 111. Inside the transparent cover 111, a shooting groove 117 for installing the camera 110 is provided. The groove surface of the shooting groove 117 on the side where the camera 110 views is set as a smooth plane to meet the shooting and viewing requirements of the camera 110. The disassembly and assembly of the camera 110 can be achieved by removing the cover plate 116.

[0054] As Figure 4 shown in the figure, an installation hole 14 for installing the pressure generator 15 is provided on the finger fixing seat 11. The transparent cover 111 also passes through the installation hole 14. An observation slot hole 13 is provided at one end of the finger fixing seat 11 where the pressure generator 15 is located. The setting of the observation slot hole 13 enables the observation of whether the finger is placed in the correct position. The correct position should place the nail bed of the finger directly below the transparent cover 111. Specifically, the pressure generator 15 includes a battery 118, and the battery 118 can be used for driving and power supply of the electromagnet and power consumption of the camera 110, etc.

[0055] Specifically, the camera 110 transmits image data to the control system via Bluetooth or other wireless devices. The transparent cover 111 is set as a transparent high-strength protective cover to prevent excessive deformation of the transparent cover 111 under electromagnetic pressure, which may lead to abnormal downward pressure on the nail bed and affect the evaluation result. The control system can be a mobile phone APP or a central monitor. The preset pressing pressure value and pressing time can be set using the control system, and at the same time, the color change of the nail bed during and after pressing can be analyzed. Through artificial training and big data analysis, a more accurate scoring standard can be achieved.

[0056] Place the target finger of the patient into the cavity of the finger fixing seat 11 so that the nail bed is at the front end of the pressure generator 15. The color of the nail bed without pressure can be recorded by the camera 110. Set the pressing pressure value and pressing time through the control system to press the nail bed and record the color of the nail bed under pressure. After reaching the pressing pressure value and pressing time, stop pressing and record the color change process of the nail bed without pressure after pressing. Judge the capillary refill time of the peripheral circulation through artificial training and big data analysis.

[0057] In summary, the present solution also has the following comprehensive effects: precise electromagnetic pressure regulation. Through the repulsive force between like poles of electromagnet 112 and electromagnet 113, combined with the limit structure of spring 17, the torsional deformation of the spring is suppressed, realizing linear pressure output in the vertical direction. The pressure value is determined by the quantitative relationship between the distance between electromagnets and the current, reducing the error; dynamic buffering mechanism. A spring 19 is arranged between the transparent cover 111 and the electromagnet 113, forming a progressive loading curve when pressure is applied, avoiding the instantaneous impact pressure exceeding the tolerance threshold of the evaluated person; optical synchronous acquisition. The camera 110 obtains the reflectance of the RGB three channels of the nail bed in real time through the smooth plane of the shooting groove 117 of the transparent cover 111. In the 530nm / 660nm dual-wavelength narrow-band filtering mode, the interference of skin color on the calculation of blood oxygen saturation is eliminated. The pressure control accuracy is improved, and the electromagnetic drive and spring limit structure reduce the standard deviation of pressure fluctuation; microcirculation dynamics capture. By analyzing the RGB gradient change rate during the pressing period and the release period, the sensitivity for detecting the subclinical characteristics of the coordinated closure of the capillary network is improved; the structural reliability is enhanced. The nested design of the sleeve 18 and the limit groove 114 limits the maximum deflection angle of the spring within a certain range; the clinical applicability is extended. The high-strength transparent cover 111 has a small deformation under pressure, ensuring a reduced optical detection error for patients with dark skin tones.

[0058] The accuracy of traditional CRT evaluation decreases in patients with dark skin tones and cannot capture the non-linear microcirculation dynamics characteristics in the pre-shock stage, such as the coordinated closure of the capillary network.

[0059] Embodiment 2: On the basis of Embodiment 1, the present invention also provides a multi-modal dynamic quantification evaluation method for peripheral circulation, which is based on magnetic-optical collaborative phase change detection and includes the following steps:

[0060] Step 1: Multi-spectral dynamic calibration;

[0061] 1. Hardware linkage control;

[0062] When the pressure generator is started, the camera 110 synchronously switches to the narrow-band filtering mode (530nm±5nm, 660nm±5nm dual channels), and the real-time mapping of the displacement h of the electromagnet B and the pressure p:

[0063]

[0064] where γ = 0.15 is the hysteresis compensation factor, and the measured pressure fluctuation < 0.02N;

[0065] 2. Skin color adaptive optical correction;

[0066] Collect the nail bed reflection spectrum R(λ) in the pre-pressing stage and calculate the skin light transmittance parameter:

[0067]

[0068] Dynamically adjust the RGB channel weights through the Beer-Lambert law:

[0069]

[0070] Step 2: Phase transition feature extraction;

[0071] 1. Capillary network modeling;

[0072] Divide the nail bed area into 20×20 microgrids, and each grid corresponds to the spin state s of the Ising model i Monte Carlo simulation of energy evolution:

[0073]

[0074] Among them, the magnetic field strength h(t) is positively correlated with the measured blood flow velocity v(t);

[0075] 2. Critical state monitoring

[0076] Calculate the change rate of program parameters:

[0077]

[0078] Trigger an early warning when the phase transition condition is met:

[0079]

[0080] Step 3: Quantum feature encoding;

[0081] 1. Color space dimensionality increase;

[0082] Map RGB pixels to a 31-dimensional Hilbert space:

[0083]

[0084] Among them, φ n is the Legendre polynomial basis function;

[0085] 2. Quantum principal component analysis;

[0086] Construct the density matrix;

[0087]

[0088] Extract the eigenvalues λ1 > λ2 > λ3 corresponding to the first 3 eigenstates as topological features;

[0089] Step 4: Multimodal adversarial training;

[0090] 1. Pathological data generation;

[0091] The generator G receives: the real data distribution z, skin parameters T s , and pathological label y;

[0092] Synthesize venous occlusion features through the physical rendering layer:

[0093]

[0094] where f c is positively correlated with the venous pressure, and σ characterizes the lesion range;

[0095] 2. Optimization of the spectral discriminator;

[0096] Design a dual-branch discrimination loss:

[0097]

[0098] Verification of implementation effect: Among them, AUC (Area Under ROC Curve) is the core index for evaluating the performance of a binary classification model. The inclusion criteria for the dataset are patients with Fitzpatrick skin types IV - VI (dark skin). The data source is a multi-center clinical trial combined with an open dataset. The specific implementation effects are as follows:

[0099]

[0100] Combined with the verification results of the implementation effect, the solution of this embodiment has the following effects:

[0101] 1. Magneto-optical coupling calibration: When inferring the pressure p through the displacement h of the electromagnet, the Landau-Lifshitz equation is introduced to describe the magnetic domain motion:

[0102]

[0103] Realize the cross-compensation of pressure-optical parameters, reducing the dark skin error to 3.2%;

[0104] 2. Quantum-classical hybrid architecture: Implement a variational quantum circuit (4 qubits) of quantum principal component analysis on an FPGA, which performs parallel operations with a traditional CNN, and the feature extraction speed is increased several times.

[0105] The above describes the embodiments of the present invention, but the present invention is not limited to the above specific implementation manners. The above specific implementation manners are merely illustrative and not restrictive. Under the inspiration of the present invention, those of ordinary skill in the art can also make many forms, all of which fall within the protection scope of the present invention.

Claims

1. A peripheral circulation function evaluation device, characterized in that Comprising: A control system and a finger fixing seat (11). A placement cavity (12) for the tester's finger to be placed is provided on the finger fixing seat (11). A pressure generator (15) is provided on the finger fixing seat (11). The pressure generator (15) is used for pressing the finger inside the placement cavity (12) required for evaluation. A camera (110) is provided at the bottom of the pressure generator (15). The control system is used for driving and controlling the pressure generator (15) and for analyzing the shooting results of the camera (110). The control system can accurately set the pressure value and pressing time of the pressing required for evaluation, and at the same time analyze the color change of the nail bed before, during and after pressing.

2. The peripheral circulation function evaluation device according to claim 1, characterized in that The pressure generator (15) includes a housing (16). A spring is provided inside the housing (16). A positioning structure is provided inside the housing (16). The positioning structure is used to prevent the spring from undergoing torsional deformation when stretching and contracting inside the housing (16).

3. The end - circulation function evaluation device according to claim 2, wherein, The spring is set as spring one (17). The positioning structure includes a limiting groove (114) and a limiting post (115). The limiting groove (114) is opened on the housing (16). The opening direction of the limiting groove (114) is the stretching direction of spring one (17). The limiting posts (115) are connected to both ends of spring one (17). The limiting posts (115) slide inside the limiting groove (114).

4. The peripheral circulation function evaluation device according to claim 2 or 3, characterized in that, The pressure generator (15) uses an electromagnet for pressure drive. The pressure generator (15) includes electromagnet one (112) and electromagnet two (113). Spring one (17) is arranged between electromagnet one (112) and electromagnet two (113) and serves as the reset structure for both of them.

5. The peripheral circulation function evaluation device according to claim 4, characterized in that, Spring one (17) is installed between the two electromagnets in a stretched state. The housing (16) is set as a structure with an opening facing downwards. Electromagnet one (112) is installed at the inner top of the housing (16). Under the electromagnetic force of opposite-sex repulsion between electromagnet one (112) and electromagnet two (113), electromagnet two (113) is driven by the electromagnetic force to provide a downward pressure.

6. The peripheral circulation function evaluation device according to claim 5, characterized in that A transparent cover (111) is provided at the bottom of the pressure generator (15). The transparent cover (111) is used to contact the finger to provide a downward pressure. The camera (110) is arranged inside the transparent cover (111). A spring two (19) is provided between the electromagnet two (113) and the transparent cover (111).

7. An end - circulatory function evaluation device according to claim 6, characterized in that, A sleeve (18) is slidably installed inside the housing (16). The transparent cover (111) is slidably installed inside the sleeve (18). The spring two (19) is arranged inside the sleeve (18) and supports between the inner bottom of the sleeve (18) and the transparent cover (111).

8. The peripheral circulation function evaluation device according to claim 7, characterized in that, A detachable cover plate (116) is provided on the transparent cover (111). A shooting groove (117) for installing the camera (110) is provided inside the transparent cover (111). The groove surface of the shooting groove (117) on the side of the camera (110) for taking pictures is set as a smooth plane to meet the shooting and viewing requirements of the camera (110).

9. The peripheral circulation function evaluation device according to claim 8, wherein The finger fixing base (11) is provided with a mounting hole (14) for mounting the pressure generator (15), and the transparent cover (111) also passes through the mounting hole (14). An observation slot hole (13) is arranged at one end of the finger fixing base (11) where the pressure generator (15) is located, and the observation slot hole (13) is used to observe whether the finger is placed in the correct position.

10. The peripheral circulation function evaluation device according to claim 1, characterized in that It also includes a multi-modal peripheral circulation dynamic quantification evaluation method, which comprises the following steps: Step S1, multi-spectral dynamic calibration: hardware linkage control, skin color adaptive optical correction; Step S2, phase change feature extraction: capillary network modeling, critical state monitoring; Step S3, quantization feature encoding: color space dimension elevation, quantum principal component analysis; Step S4, multi-modal adversarial training: pathological data generation, spectral discriminator optimization.

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